A clinical sample collection and multi-omics typing integrated device

Abstract

The utility model relates to clinical sample collection and multiomics analysis technical field, and disclose a kind of clinical sample collection and multiomics typing integrated device, including support, test table and several analysis probes;By controlling sample container to downwardly pressurized positioning needle, make several positioning needles below sample container move down and complete the contact of first magnet and second magnet, and further realize the fixation of sample container, and further make the device adapt to different specifications of sample container and be fixed, ensure the stability of sample container, by pulling analysis probe, make analysis probe extend to sample container, test table and cleaning box respectively and complete the acquisition, processing and cleaning of analysis probe of sample, at this time, stop exerting external force, and contraction spring can be used to pull analysis probe reset, and the bottom of support is fixedly installed with several pulleys, so that the device can be moved to ward, increase the convenience of clinical sample collection and multiomics analysis.

Description

Technical Field

[0001] This utility model relates to the field of clinical sample collection and multi-omics analysis technology, specifically to an integrated device for clinical sample collection and multi-omics typing. Background Technology

[0002] Clinical sample collection and multi-omics genotyping integrated devices represent an important development direction of modern medical testing technology. They integrate sample collection, processing and analysis functions into one, realizing full automation from "sample in" to "result out". Such devices have broad application prospects in infectious disease prevention and control, cancer screening, precision medicine and other fields, and can significantly improve testing efficiency and accuracy, and reduce operational complexity and contamination risk.

[0003] Combining sample collection, processing, and multi-omics analysis functions aims to improve sample processing efficiency and data integration capabilities in clinical research and precision medicine. However, in the process of collecting clinical samples for multi-omics analysis, it is still necessary to send the samples to the laboratory for multi-omics analysis after collection. Moreover, the specifications of the containers used for sample collection are not fixed, so it is impossible to provide suitable clamping tools. During the experimental analysis, problems such as container tipping or displacement may occur. At the same time, different analytical probes are concentrated together, which can easily cause chaos on the experimental table. Furthermore, there is the problem of timely cleaning of probes after use. Therefore, there is a need to provide an integrated device for clinical sample collection and multi-omics typing. Utility Model Content

[0004] The purpose of this invention is to provide an integrated device for clinical sample collection and multi-omics typing, in order to solve the problems of cumbersome and inefficient sample collection and multi-omics analysis steps in existing devices, as well as the confusion caused by the use of multiple probes on the test bench.

[0005] To achieve the above objectives, this utility model provides the following technical solution: a clinical sample collection and multi-omics genotyping integrated device, comprising a support, a test platform, and several analytical probes, wherein a positioning mechanism is provided on the upper side of the support; the positioning mechanism comprises a mounting box and a fixing plate, the mounting box is fixedly mounted on the upper side of the support, and several positioning pins are slidably mounted through the mounting box, a first magnet is fixedly mounted on the lower side of each of the positioning pins, and a first spring is fixedly mounted between each of the positioning pins and the mounting box; two limiting rods are fixedly mounted side by side on both sides of the fixing plate, and several second magnets are fixedly mounted on the upper side of the fixing plate, and four second springs are fixedly mounted between the fixing plate and the support.

[0006] Preferably, the mounting box has a slot in the middle, and the first spring is located between the positioning pin and the lower side of the slot.

[0007] Preferably, the positioning pins and the second magnets are arranged at equal intervals, and the positioning pins are located directly above the second magnets.

[0008] Preferably, each of the four limiting rods has a protrusion fixedly installed in the middle, and each of the four limiting rods is slidably installed on the mounting box.

[0009] Preferably, a sorting mechanism is provided on a plurality of analytical probes. The sorting mechanism includes an analytical stage and an acoustic cleaning stage. The analytical stage is fixedly installed on one side of the support, and a plurality of wires are fixedly installed between the input end of the analytical stage and the plurality of analytical probes. A contraction spring is sleeved on the outside of each of the plurality of wires. A cleaning box is movably installed on the upper part of the acoustic cleaning stage.

[0010] Preferably, the two ends of the contraction spring are fixedly connected to the test bench and the analysis probe, respectively, and the wires are all slidably mounted on the test bench.

[0011] Preferably, the test bench and the mounting box are fixedly installed side by side on the upper side of the support, and a number of pulleys are fixedly installed at the bottom of the support.

[0012] Compared with the prior art, the beneficial effects of this utility model are:

[0013] 1) This clinical sample collection and multi-omics genotyping integrated device controls the downward pressure of the sample container on the positioning pins, causing several positioning pins below the sample container to move downwards to complete the contact between the first magnet and the second magnet. Under the action of magnetic attraction, the positioning pins will be fixed, thereby fixing the sample container. When the sample container is removed, the fixing plate is pressed further to move the second magnet away from the first magnet, thereby resetting the positioning pins. This allows the device to adapt to the fixing of sample containers of different sizes, ensuring the stability of the sample container.

[0014] 2) This integrated clinical sample collection and multi-omics genotyping device allows different analytical probes to be pulled to extend to the sample container, test bench, and cleaning box to complete sample acquisition, processing, and cleaning of the analytical probes. When the external force is stopped, the spring is contracted to pull the analytical probes back to their original position. Several pulleys are fixedly installed at the bottom of the support, allowing the device to be moved to the ward, increasing the convenience of clinical sample collection and multi-omics analysis. Attached Figure Description

[0015] Figure 1 This is a three-dimensional structural diagram of a clinical sample collection and multi-omics typing integrated device according to an embodiment of the present invention;

[0016] Figure 2 This is a cross-sectional view of the mounting box in an embodiment of the present utility model;

[0017] Figure 3 As an embodiment of this utility model Figure 2 Enlarged view of A in the middle;

[0018] Figure 4 This is a three-dimensional structural diagram of the first magnet and the second magnet in an embodiment of this utility model;

[0019] Figure 5 This is a three-dimensional structural exploded view of the sorting mechanism in an embodiment of this utility model.

[0020] In the diagram: 1. Support; 2. Test bench; 3. Analytical probe; 4. Positioning mechanism; 401. Mounting box; 402. Fixing plate; 403. Positioning pin; 404. First magnet; 405. First spring; 406. Limiting rod; 407. Second magnet; 408. Second spring; 5. Cleaning mechanism; 501. Analytical bench; 502. Acoustic cleaning bench; 503. Wire; 504. Retraction spring; 505. Cleaning box. Detailed Implementation

[0021] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0022] Example 1

[0023] Combination Figures 1-4 A clinical sample collection and multi-omics typing integrated device includes a support 1, a test platform 2, and several analytical probes 3. A positioning mechanism 4 is provided on the upper side of the support 1. The positioning mechanism 4 includes a mounting box 401 and a fixing plate 402. The mounting box 401 is fixedly installed on the upper side of the support 1, and several positioning pins 403 are slidably installed through the mounting box 401. A first magnet 404 is fixedly installed on the lower side of each of the positioning pins 403, and a first spring 405 is fixedly installed between each of the positioning pins 403 and the mounting box 401. Two limiting rods 406 are fixedly installed side by side on both sides of the fixing plate 402, and several second magnets 407 are fixedly installed on the upper side of the fixing plate 402. Four second springs 408 are fixedly installed between the fixing plate 402 and the support 1.

[0024] A slot is provided in the middle of the mounting box 401. The first spring 405 is located between the positioning pin 403 and the lower side of the slot. The function of the mounting box 401 is to confine the positioning pin 403 within it and prevent it from detaching from the mounting box 401. In use, when the sample container is pressed onto the positioning pins 403, it can be embedded between the positioning pins 403. The positioning pins 403 and the second magnets 407 are arranged equidistantly, and the positioning pins 403 are located directly above the second magnets 407. When the sample container is pressed onto the positioning pins 403... 3. When it moves downward, the first magnet 404 will disengage from the second magnet 407 and magnetic attraction will occur, fixing the positioning pin 403 below the sample container, thereby completing the fixing of the sample container. The four limiting rods 406 are all fixedly installed with protrusions in the middle, and the four limiting rods 406 are all slidably installed on the mounting box 401, which can ensure that the fixing plate 402 is slidably installed on the lower side of the mounting box 401. When pressure is applied downward to the fixing plate 402, the second magnet 407 will separate from the first magnet 404, thereby realizing the reset of the positioning pin 403.

[0025] Example 2

[0026] See Figure 5 A sorting mechanism 5 is provided on several analytical probes 3. The sorting mechanism 5 includes an analytical table 501 and an acoustic cleaning table 502. The analytical table 501 is fixedly installed on one side of the support 1, and several wires 503 are fixedly installed between the input end of the analytical table 501 and several analytical probes 3. Each of the several wires 503 is fitted with a contraction spring 504. A cleaning box 505 is movably installed on the upper part of the acoustic cleaning table 502.

[0027] The two ends of the contraction spring 504 are fixedly connected to the test platform 2 and the analytical probe 3, respectively. Several wires 503 are slidably installed on the test platform 2, so that the contraction spring 504 provides traction between the analytical probes 3. At the same time, the wires 503 input sample information from the analytical probes 3 into the analytical platform 501. In use, the analytical probe 3 is pulled to extend it to obtain the sample in the container, and further multi-omics analysis is performed on the test platform 2. At the same time, the analytical probe 3 is cleaned in the cleaning box 505. When the external force is stopped, the contraction spring 504 can pull the analytical probe 3 back to its original position. The test platform 2 and the mounting box 401 are fixedly installed side by side on the upper side of the support 1. Several pulleys are fixedly installed at the bottom of the support 1, so that the device can be moved to the ward, increasing the convenience of clinical sample collection and multi-omics analysis.

[0028] In actual operation, by controlling the sample container to press down on the positioning pins 403, several positioning pins 403 below the sample container move downward to complete the contact between the first magnet 404 and the second magnet 407. Under the action of magnetic attraction, the positioning pins 403 will be fixed, thereby fixing the sample container. When the sample container is removed, the fixing plate 402 is pressed further to make the second magnet 407 move away from the first magnet 404, so that the positioning pins 403 can be reset.

[0029] By pulling different analytical probes 3, the analytical probes 3 can be extended to the sample container, the test bench 2 and the cleaning box 505 respectively to complete the sample acquisition, processing and cleaning of the analytical probes 3. At this time, the external force is stopped, and the spring 504 is contracted to pull the analytical probes 3 back to their original position. Several pulleys are fixedly installed at the bottom of the support 1, so that the device can be moved to the ward, increasing the convenience of clinical sample collection and multi-omics analysis.

[0030] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to the embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A clinical sample collection and multi-omics typing integrated device, comprising a support (1), a test bench (2), and a plurality of analytical probes (3), characterized in that: A positioning mechanism (4) is provided on the upper side of the support (1); The positioning mechanism (4) includes a mounting box (401) and a fixing plate (402). The mounting box (401) is fixedly installed on the upper side of the support (1), and a plurality of positioning pins (403) are slidably installed through the mounting box (401). A first magnet (404) is fixedly installed on the lower side of each of the positioning pins (403), and a first spring (405) is fixedly installed between the positioning pins (403) and the mounting box (401). Two limiting rods (406) are fixedly installed side by side on both sides of the fixing plate (402), and a plurality of second magnets (407) are fixedly installed on the upper side of the fixing plate (402). Four second springs (408) are fixedly installed between the fixing plate (402) and the support (1).

2. The integrated device for clinical sample collection and multi-omics typing according to claim 1, characterized in that: The mounting box (401) has a slot in the middle, and the first spring (405) is located between the positioning pin (403) and the lower side of the slot.

3. The integrated device for clinical sample collection and multi-omics typing according to claim 2, characterized in that: The positioning pins (403) and the second magnets (407) are arranged at equal intervals, with the positioning pins (403) located directly above the second magnets (407).

4. The integrated device for clinical sample collection and multi-omics typing according to claim 2, characterized in that: Each of the four limiting rods (406) has a protrusion fixedly installed in the middle, and each of the four limiting rods (406) is slidably installed on the mounting box (401).

5. The integrated device for clinical sample collection and multi-omics typing according to claim 2, characterized in that: A sorting mechanism (5) is provided on several of the analytical probes (3). The sorting mechanism (5) includes an analytical table (501) and an acoustic cleaning table (502). The analytical table (501) is fixedly installed on one side of the support (1). Several wires (503) are fixedly installed between the input end of the analytical table (501) and several analytical probes (3). A contraction spring (504) is sleeved on the outside of each of the several wires (503). A cleaning box (505) is movably installed on the upper part of the acoustic cleaning table (502).

6. The integrated device for clinical sample collection and multi-omics typing according to claim 5, characterized in that: The two ends of the contraction spring (504) are fixedly connected to the test bench (2) and the analysis probe (3) respectively, and several of the wires (503) are slidably installed on the test bench (2) through the test bench (2).

7. The integrated device for clinical sample collection and multi-omics typing according to claim 5, characterized in that: The test bench (2) and the mounting box (401) are fixedly installed side by side on the upper side of the support (1), and several pulleys are fixedly installed at the bottom of the support (1).

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