A vertical chromatographic detection device capable of self-sampling

Abstract

This invention discloses a vertical chromatography detection device with self-aspiration sampling capability, relating to the field of material analysis by determining the chemical properties of materials. It includes a sampling component and a storage component. The sampling component includes a detection tube with a buffer tube and a capillary tube at its sampling end. The buffer tube has an annular groove around its periphery. A chromatography test strip is installed inside the detection tube, and the sample application end is located inside the buffer tube. The storage component includes a storage tube, a base, and a seal. The storage tube has a frustum-shaped flange on the outer side of its port and a seal. The base has multiple limiting plates inside, at least two of which have protrusions. The storage tube is embedded between the limiting plates, and the frustum-shaped flange is inverted onto the protrusions. When the buffer tube and capillary tube are inserted into the storage tube, the annular groove covers the outside of the frustum-shaped flange. This invention utilizes a capillary tube to achieve self-aspiration sampling and uses the storage component to pre-store and release diluent, making operation simple.

Description

Technical Field

[0001] This utility model relates to the field of materials analysis by measuring the chemical properties of materials, specifically a vertical chromatography detection device capable of self-absorption sampling. Background Technology

[0002] Home testing devices for patients have received widespread attention. However, devices for testing bodily fluid samples, such as blood samples, are less commonly used. This is because the processes of blood sample collection, diluent storage and transportation, and sample loading are complex. Existing chromatography devices often require additional pipetting, making sample collection and diluent usage cumbersome and difficult for non-professionals to operate. Therefore, there is a need to design a home testing device that is easy to collect samples, simple to operate, and portable. Utility Model Content

[0003] The purpose of this invention is to provide a vertical chromatography detection device with self-absorption sampling capability, which aims to overcome the problem in the prior art that the complex processes of blood sample collection, diluent storage and transportation, and sample addition make it difficult for non-professionals to operate.

[0004] To achieve this objective, the present invention provides the following technical solution:

[0005] A vertical chromatography detection device with self-absorption sampling capability includes a sampling component and a storage component. The sampling component includes a detection tube, the sampling end of which is provided with a buffer tube and a capillary tube connected in sequence, and an annular groove is provided on the periphery of the buffer tube. A chromatography test strip is assembled inside the detection tube, and the sample application end of the chromatography test strip is located inside the buffer tube.

[0006] The liquid storage assembly includes a liquid storage tube, a base, and a seal. The outer side of the port of the liquid storage tube is provided with a frustum-shaped flange, and the port is provided with the seal. The base is provided with multiple limiting plates, and at least two of the limiting plates are provided with protrusions. The liquid storage tube is embedded between the multiple limiting plates, and the frustum-shaped flange is upside down on the protrusions. When the buffer tube and capillary tube are inserted into the liquid storage tube, the annular groove covers the outside of the frustum-shaped flange.

[0007] Furthermore, the detection tube is provided with a first connector, the base is provided with a second connector, and the outer peripheral surface of the frustum-shaped flange is provided with a flange; when the buffer tube and capillary tube are inserted into the liquid storage tube, the first connector is inserted into the second connector, and the first connector, flange and limiting plate abut against each other in sequence.

[0008] Furthermore, the outer wall of the flange abuts against the inner wall of the second connector.

[0009] Furthermore, the port of the liquid storage tube protrudes from the second connector.

[0010] Furthermore, the sampling and testing assembly also includes a mounting frame, and both sides of the mounting frame are provided with snap-fit ​​plates (22), which abut against the inner wall of the detection tube; the mounting frame is provided with a mounting groove, and one end of the mounting groove is provided with an extension, which is inserted into the inside of the buffer tube; the chromatography test strip is disposed in the mounting groove.

[0011] Furthermore, the inner wall profile of the cross-section of the detection tube is elliptical, and the snap-fit ​​plate abuts against the long axis end of the ellipse on the inner wall of the detection tube.

[0012] Furthermore, the sampling and testing assembly also includes a top cover, which is disposed at the port of the detection tube, and the two ends of the mounting bracket abut against the top cover and the detection tube, respectively.

[0013] Furthermore, the top cover is provided with a positioning block, the mounting bracket is provided with a positioning hole, and the positioning block is embedded in the positioning hole, so that the chromatography test strip is held by the positioning block and the mounting groove.

[0014] Furthermore, the inner wall of the detection tube is provided with a recess, and the top cover is provided with a convex part, with the recess and the convex part interlocking.

[0015] Furthermore, the sample application end of the chromatography strip abuts against the end face of the capillary and is located beside the opening of the capillary.

[0016] Compared with the prior art, this utility model has the following advantages:

[0017] Firstly, this invention utilizes capillary action to achieve self-absorption of samples, eliminating the need for additional pipetting equipment and reducing operational difficulty. Secondly, by incorporating a buffer tube, space is provided for contact between the sample, diluent, and chromatographic test strip, ensuring the actual amount of sample used and improving detection accuracy. Thirdly, the liquid storage component is pre-filled with liquid, and the matching structure of the annular groove and frustoconical flange forms a positioning when the sampling component and the liquid storage component are inserted, ensuring a stable and reliable detection process.

[0018] Secondly, this utility model achieves a stable connection between the sampling component and the liquid storage component through the insertion and cooperation of the first connector and the second connector, as well as the sequential abutment of the flange and the limiting plate, thus preventing loosening during use.

[0019] Thirdly, this utility model further enhances the sealing performance and connection strength between the liquid storage tube and the detection tube by abutting the outer wall of the flange with the inner wall of the second connector.

[0020] Fourth, by protruding the liquid storage tube port from the second connector, this utility model makes it easier for users to open the seal and improves operational convenience.

[0021] Fifth, this utility model, by setting up a mounting bracket, utilizes the contact between the snap-fit ​​plate and the inner wall of the detection tube, and the insertion of the extension portion into the buffer tube, to stably fix the chromatographic test strip inside the detection tube, preventing displacement. Furthermore, a positioning block and positioning hole fitting structure is provided between the top cover and the mounting bracket to further secure the mounting bracket, while simultaneously protecting the chromatographic test strip from contamination.

[0022] Sixth, this utility model achieves directional assembly of the mounting frame by setting the inner wall of the cross-section of the detection tube to an elliptical shape and having the snap-fit ​​plate abut against the end of the long axis, thus preventing the chromatography test strip from deflecting.

[0023] Seventh, this utility model improves chromatography efficiency and detection sensitivity by placing the sample application end of the chromatography test strip against the capillary end face and located beside the tube opening. Attached Figure Description

[0024] Figure 1 This is a schematic diagram of the structure of the present invention when the sampling component and the liquid storage component are not combined.

[0025] Figure 2 This is a schematic diagram of the structure of the sampling and testing component and the liquid storage component working together in this utility model.

[0026] Figure 3 For the explosion of this utility model Figure 1 .

[0027] Figure 4 For the explosion of this utility model Figure 2 .

[0028] Figure 5 This is a cross-sectional view of the sampling component and the liquid storage component in this utility model when they are working together.

[0029] Explanation of reference numerals in the attached figures

[0030] Sample collection assembly - 100; Top cover - 1; Vent hole - 11; Positioning block - 12; Protrusion - 13; Mounting bracket - 2; Positioning hole - 21; Snap-fit ​​plate - 22; Mounting groove - 23; Extension - 24; Chromatography test strip - 3; Detection tube - 4; First connector - 40; Annular groove - 41; Buffer tube - 42; Capillary tube - 43; Recess - 44.

[0031] Liquid storage assembly - 200; Liquid storage tube - 5; Frustum-shaped flange - 51; Flanged edge - 511; Base - 6; Second connector - 60; Limiting plate - 61; Protrusion - 611; Seal - 7. Detailed Implementation

[0032] The specific embodiments of this utility model are described below with reference to the accompanying drawings. Many details are described below to provide a comprehensive understanding of this utility model; however, those skilled in the art can implement this utility model without these details.

[0033] like Figures 1 to 5 As shown, a vertical chromatography detection device with self-priming sampling capability includes a sampling component 100 and a storage component 200. The sampling component 100 stores the chromatography test strip 3 and the sample required for detection, such as finger prick blood. The storage component 200 stores the liquid required for detection, such as a diluent. In use, the sampling component 100 and the storage component 200 work together to complete the detection.

[0034] The sampling assembly 100 includes a detection tube 4 and a chromatography strip 3. The sampling end of the detection tube 4 is provided with a buffer tube 42 and a capillary tube 43 connected in sequence. The detection tube 4 has an annular groove 41 around the buffer tube 42. The chromatography strip 3 is assembled inside the detection tube 4, and the sample application end of the chromatography strip 3 is located inside the buffer tube 42.

[0035] Preferably, the buffer tube 42, capillary tube 43, and detection tube 4 are integrally formed. Of course, it is not excluded that the buffer tube 42 and capillary tube 43 are integrally formed, and the buffer tube 42 and detection tube 4 are threaded together.

[0036] It should be noted that by designing the size of the capillary 43, the sample aspiration volume can be controlled to achieve quantitative detection.

[0037] Chromatographic test strip 3 is an existing test strip selected according to the testing requirements. Its specific structure will not be described in detail here. The above-mentioned sample application end is usually the end of the existing chromatographic test strip 3 with a sample pad.

[0038] Preferably, the sample application end of the chromatographic test strip 3 is placed against the end face of the capillary 43 to facilitate chromatography. Furthermore, the sample application end of the chromatographic test strip 3 is located beside the opening of the capillary 43 to allow the sample and solution to smoothly enter the buffer tube 42 from the capillary 43. The buffer tube 42 provides space for contact between the sample, diluent, and chromatographic test strip 3, preventing sample residue from remaining on the mounting frame 2, ensuring the actual amount of sample used, and improving detection accuracy.

[0039] It should be noted that the user can observe the detection area (such as the T line) of the chromatography strip 3 through the detection tube 4.

[0040] like Figures 2 to 5 As shown, in one specific embodiment, the sampling assembly 100 further includes a mounting bracket 2 for assembling the chromatography strip 3 inside the detection tube 4.

[0041] Specifically, the mounting frame 2 has a mounting groove 23 and snap-fit ​​plates 22 on both sides. One end of the mounting groove 23 has an extension 24. After the chromatographic test strip 3, the mounting frame 2, and the detection tube 4 are assembled, the chromatographic test strip 3 is placed in the mounting groove 23, with the sample application end of the chromatographic test strip 3 facing the extension 24; the snap-fit ​​plates 22 on both sides of the mounting frame 2 abut against the inner wall of the detection tube 4, and the extension 24 is inserted into the buffer tube 42. By utilizing the interference fit between the snap-fit ​​plates 22 and the inner wall of the detection tube 4, and the insertion fit between the extension 24 and the buffer tube 42, the mounting frame 2 is fixed inside the detection tube 4, while the sample application end of the chromatographic test strip 3 is located inside the buffer tube 42.

[0042] like Figures 2 to 5 As shown, preferably, the inner wall profile of the cross-section of the detection tube 4 is elliptical, and the snap-fit ​​plate 22 abuts against the major axis end of the ellipse on the inner wall of the detection tube 4. In other words, the width of the detection tube 4 is approximately equal to the major axis end of the ellipse on the inner wall of the detection tube 4. This allows the mounting bracket 2 and the chromatography strip 3 to be oriented and assembled inside the detection tube 4.

[0043] Preferably, the inner wall of the detection tube 4 is provided with a recess 44, and the top cover 1 is provided with a protrusion 13. After the detection tube 4 and the top cover 1 are assembled, the recess 44 and the protrusion 13 are engaged to achieve directional assembly.

[0044] Alternatively, an installation structure can be set inside the detection tube 4 to directly assemble the chromatographic test strip 3, so that the chromatographic test strip 3 is fixed and the sample application end is located inside the buffer tube 42, thus replacing the mounting bracket 2.

[0045] like Figures 2 to 5 As shown, preferably, the sampling assembly 100 also includes a top cover 1, which is disposed at the port of the detection tube 4, and the two ends of the mounting bracket 2 abut against the top cover 1 and the detection tube 4 respectively. During assembly, the mounting bracket 2 carrying the chromatographic test strip 3 is first inserted into the detection tube 4 from the port of the detection tube 4, and then the top cover 1 is assembled at the port of the detection tube 4 to seal the chromatographic test strip 3 and prevent it from being contaminated.

[0046] like Figures 2 to 5 As shown, preferably, the top cover 1 is provided with a positioning block 12, and the mounting bracket 2 is provided with a positioning hole 21. After the top cover 1, the mounting bracket 2, and the detection tube 4 are assembled, the positioning block 12 is embedded in the positioning hole 21 to further fix the mounting bracket 2. More preferably, both ends of the mounting bracket 2 abut against the top cover 1 and the detection tube 4 respectively to further fix the mounting bracket 2.

[0047] Preferably, the top cover 1 is provided with an exhaust port 11 to balance the internal and external air pressure of the detection tube 4, making the chromatography process smoother.

[0048] like Figures 1 to 5As shown, the liquid storage assembly 200 includes a liquid storage tube 5, a base 6, and a seal 7. The outer side of the port of the liquid storage tube 5 is provided with a frustum-shaped flange 51, and the port is provided with a seal 7. The liquid storage tube 5 is pre-filled with the liquid required for testing.

[0049] like Figure 1 and Figure 3 As shown, preferably, the seal 7 is, but is not limited to, a plastic film.

[0050] like Figures 3 to 5 As shown, the base 6 has multiple limiting plates 61 inside, and at least two of the limiting plates 61 have protrusions 611; after the liquid storage tube 5 and the base 6 are assembled, the liquid storage tube 5 is embedded between the multiple limiting plates 61, and the frustum-shaped flange 51 is upside down on the protrusions 611, and the base 6 and the liquid storage tube 5 are fixed relative to each other by interference fit.

[0051] like Figure 1 , Figure 3 and Figure 5 As shown, preferably, after the liquid storage tube 5 and the base 6 are assembled, the port of the liquid storage tube 5 protrudes from the base 6, making it convenient to open the seal 7 during use.

[0052] like Figures 1 to 5 As shown, preferably, the detection tube 4 is provided with a first connector 40. The base 6 is provided with a second connector 60, and the outer peripheral surface of the frustum-shaped flange 51 is provided with a flange 511.

[0053] When the sampling component 100 is used in conjunction with the liquid storage component 200, the buffer tube 42 and the capillary tube 43 are inserted into the liquid storage tube 5. At this time, the first connector 40 is inserted into the second connector 60; the first connector 40, the flange 511 and the limiting plate 61 abut against each other in sequence; the annular groove 41 covers the outside of the frustum-shaped flange 51.

[0054] Preferably, after the liquid storage tube 5 and the base 6 are assembled, the port of the liquid storage tube 5 protrudes from the second connector 60, making it convenient to open the seal 7 during use; the outer side wall of the flange 511 abuts against the inner side wall of the second connector 60 to reinforce the liquid storage tube 5.

[0055] How to use this utility model:

[0056] After the sampling component 100 and the liquid storage component 200 are assembled separately, they are packaged separately.

[0057] First, the sample collection component 100 is used to automatically collect a sample (such as fingertip blood) using the capillary action of the capillary tube 43.

[0058] Then, open the seal 7 of the liquid storage tube 5 and place the liquid storage assembly 200 vertically upward on the table.

[0059] Finally, the buffer tube 42 and capillary tube 43 are gradually inserted into the liquid storage tube 5 from top to bottom until the sampling assembly 100 and the liquid storage assembly 200 are in the following position. Figure 2 and Figure 5 The state shown is as follows. During insertion, the sample inside the capillary 43 is pushed into the buffer tube 42, contacting the sample application end of the chromatography strip 3. At the same time, the liquid (such as diluent) in the reservoir tube 5 is pushed into the capillary 43, and then enters the buffer tube 42 to mix with the sample. The chromatography strip 3 then performs chromatography. Wait and observe the test results.

[0060] The above are merely specific embodiments of this utility model, but the design concept of this utility model is not limited thereto. Any non-substantial modifications made to this utility model using this concept shall be considered as an infringement of the protection scope of this utility model.

Claims

1. A vertical chromatography detection device capable of self-aspiration sampling, characterized in that: The sample collection unit includes a sampling component (100) and a storage component (200). The sampling component includes a detection tube (4). The sampling end of the detection tube (4) is provided with a buffer tube (42) and a capillary tube (43) connected in sequence, and an annular groove (41) is provided on the periphery of the buffer tube (42). The detection tube (4) is equipped with a chromatography test strip (3), and the sample application end of the chromatography test strip (3) is located inside the buffer tube (42). The liquid storage assembly (200) includes a liquid storage tube (5), a base (6) and a seal (7). The outer side of the port of the liquid storage tube (5) is provided with a frustum-shaped flange (51) and the port is provided with the seal (7). The base (6) is provided with multiple limiting plates (61) inside, and at least two of the limiting plates (61) are provided with protrusions (611). The liquid storage tube (5) is embedded between the multiple limiting plates (61) and the frustum-shaped flange (51) is upside down on the protrusions (611). When the buffer tube (42) and the capillary tube (43) are inserted into the liquid storage tube (5), the annular groove (41) covers the outside of the frustum-shaped flange (51).

2. The vertical chromatography detection device with self-aspiration sampling capability according to claim 1, characterized in that: The detection tube (4) is provided with a first connector (40), the base (6) is provided with a second connector (60), and the outer circumferential surface of the frustum flange (51) is provided with a flange (511); when the buffer tube (42) and the capillary tube (43) are inserted into the liquid storage tube (5), the first connector (40) is inserted into the second connector (60), and the first connector (40), the flange (511) and the limiting plate (61) abut against each other in sequence.

3. The vertical chromatography detection device with self-aspiration sampling capability according to claim 2, characterized in that: The outer wall of the flange (511) abuts against the inner wall of the second connector (60).

4. The vertical chromatography detection device with self-aspiration sampling capability according to claim 1, characterized in that: The port of the liquid storage tube (5) protrudes from the second connector (60).

5. The vertical chromatography detection device with self-aspiration sampling capability according to claim 1, characterized in that: The sampling and testing assembly also includes a mounting frame (2), with snap-fit ​​plates (22) on both sides of the mounting frame (2), which abut against the inner wall of the detection tube (4); the mounting frame (2) has a mounting groove (23), with an extension (24) at one end of the mounting groove (23), which is inserted into the buffer tube (42); the chromatography test strip (3) is set in the mounting groove (23).

6. The vertical chromatography detection device with self-aspiration sampling capability according to claim 5, characterized in that: The inner wall profile of the cross-section of the detection tube (4) is elliptical, and the snap-fit ​​plate (22) abuts against the long axis end of the elliptical inner wall of the detection tube (4).

7. A vertical chromatography detection device capable of self-aspiration sampling according to claim 5 or 6, characterized in that: The sampling and testing assembly also includes a top cover (1), which is located at the port of the detection tube (4), and the two ends of the mounting bracket (2) abut against the top cover (1) and the detection tube (4) respectively.

8. The vertical chromatography detection device with self-aspiration sampling capability according to claim 7, characterized in that: The top cover (1) is provided with a positioning block (12), the mounting bracket (2) is provided with a positioning hole (21), and the positioning block (12) is embedded in the positioning hole (21). The chromatography test strip (3) is held by the positioning block (12) and the mounting groove (23).

9. A vertical chromatography detection device capable of self-aspiration sampling according to claim 7, characterized in that: The inner wall of the detection tube (4) is provided with a recess (44), and the top cover (1) is provided with a protrusion (13), and the recess (44) and the protrusion (13) are fitted together.

10. A vertical chromatography detection device capable of self-aspiration sampling according to claim 1 or 5, characterized in that: The sample application end of the chromatography strip (3) is in contact with the end face of the capillary (43) and is located next to the opening of the capillary (43).

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