A mixed preparation equipment for chlorpheniramine maleate tablets

Abstract

The utility model relates to the technical field of pharmaceutical preparations, concretely relates to a maleic acid chlorpheniramine maleate tablet mixed preparation equipment, including mainframe, the intermediate horizontal arrangement of mainframe is provided with stirring drive shaft, the outer end of stirring drive shaft is connected and is provided with V type mixing cylinder, the inside symmetry of V type mixing cylinder is provided with first mixing bin and second mixing bin and leans. The telescopic sleeve is driven by the pneumatic telescopic link to extend, the embedded joint is connected with the feed port or the discharge port, the center top pressure rod synchronously presses the sealing cover plate to slide to the inside to open the feed port or the discharge port to carry out the up and down material operation, and when the telescopic sleeve is driven by the pneumatic telescopic link to retract, the embedded joint is separated with the feed port or the discharge port, the sealing cover plate is reset and reseals the feed port or the discharge port through the traction sealing spring, not only guarantees the sealing property of material in the mixing process, prevents the outside pollution, and realizes the automatic operation through the pneumatic control, is favorable for improving the processing efficiency and quality.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical preparation technology, and in particular to a mixing and preparation equipment for chlorpheniramine maleate tablets. Background Technology

[0002] Chlorpheniramine maleate tablets are a classic first-generation antihistamine, primarily used to treat allergic diseases such as urticaria, eczema, and allergic rhinitis. Its core ingredient is chlorpheniramine maleate, requiring a rigorous mixing and preparation process to ensure drug homogeneity and stability. The key equipment for this mixing process is a V-type mixer, whose structure mainly consists of a symmetrical V-shaped stainless steel cylinder and a drive system. The cylinder's rotation generates material convection and diffusion, ensuring uniform mixing.

[0003] However, the current V-type mixer requires manual opening and closing of the sealing cover repeatedly during the feeding and unloading process, which is cumbersome. When feeding, the top sealing cover must be removed manually to pour out the premixed material. When unloading, the bottom valve must be adjusted and tools must be used to collect the particles. Manual operation prolongs the production cycle, increases the risk of exposure of intermediate products, and may cause microbial contamination or moisture absorption and clumping. Frequent opening of the cover disrupts the pressure gradient of the clean area, increases the risk of dust diffusion, and affects the quality of medicines. Operators need to participate in the material transfer process throughout, making it difficult to achieve continuous production. Utility Model Content

[0004] In view of this, the purpose of this utility model is to propose a mixing and preparation equipment for chlorpheniramine maleate tablets, so as to solve the problem that the current V-type mixer requires manual repeated opening and closing of the sealing cover during the feeding and unloading process, which affects the production quality and efficiency.

[0005] To achieve the above objectives, this utility model provides a mixing and preparation device for chlorpheniramine maleate tablets, including a main frame, a stirring drive shaft horizontally arranged in the middle of the main frame, and a V-shaped mixing cylinder connected to the outer end of the stirring drive shaft;

[0006] The V-shaped mixing cylinder is symmetrically and inclinedly arranged with a first mixing chamber and a second mixing chamber. The top of the first mixing chamber and the second mixing chamber are both provided with a feed inlet. The bottom of the V-shaped mixing cylinder is provided with a discharge mixing cylinder and a discharge outlet is provided at the bottom of the discharge mixing cylinder.

[0007] Both the inlet and outlet are fitted with sliding sealing covers, and the outer side of the sealing covers is connected with a traction sealing spring. The traction sealing spring keeps the sealing covers tightly fitted to the edges of the inlet and outlet to maintain a seal.

[0008] The top left and right sides of the main frame are symmetrically inclined with a feeding cylinder, and the bottom center of the main frame is provided with a feeding cylinder. The outer ends of the feeding cylinder and the feeding cylinder are both nested and slidably provided with telescopic sleeves. The outer side of the telescopic sleeve is connected with a pneumatic telescopic rod. The outer end of the telescopic sleeve is provided with a fitting interface. The fitting interface is configured to cooperate with the feed port and the discharge port. A central pressure rod is fixedly connected in the middle of the fitting interface.

[0009] Furthermore, a central guide sleeve is connected to the middle of the outer side of both the inlet and outlet, and a central guide rod is connected to the center of the outer side of the sealing cover. The central guide rod is nested and slidably disposed inside the central guide sleeve, and the sealing cover is slidably connected to the central guide sleeve through the central guide rod.

[0010] Furthermore, a fixed support shaft and a stirring drive shaft are respectively connected to the left and right sides of the V-shaped mixing cylinder. The fixed support shaft and the stirring drive shaft are respectively installed through the left and right side walls of the V-shaped mixing cylinder. The stirring drive shaft is fixedly connected to the V-shaped mixing cylinder. A closed bushing is provided in the middle of the left side wall of the V-shaped mixing cylinder. The fixed support shaft is rotatably connected to the V-shaped mixing cylinder through the closed bushing.

[0011] Furthermore, a main stirring shaft is provided at the center of the discharge mixing cylinder, and multiple mixing blades are evenly arranged around the outside of the main stirring shaft. The mixing blades are rotatably connected to the discharge mixing cylinder through the main stirring shaft. A main drive bevel gear is connected to the top of the main stirring shaft, and a fixed bevel gear is connected to the outer end of the fixed support shaft. The fixed bevel gear and the main drive bevel gear are meshed with each other.

[0012] Furthermore, a secondary stirring shaft is rotatably connected to the center of both the first and second mixing chambers. Multiple mixing blades are also evenly arranged around the outer side of the secondary stirring shaft. A secondary drive gear is connected to the inner end of the secondary stirring shaft. A linkage bevel gear is connected above the main drive bevel gear. The linkage bevel gear and the secondary drive gear are meshed with each other.

[0013] Furthermore, a flexible scraper is connected to the outer end of the mixing impeller, and the flexible scraper is in close contact with the inner walls of the first mixing chamber, the second mixing chamber, and the discharge mixing cylinder.

[0014] The beneficial effects of this utility model are as follows: As can be seen from the above description, the chlorpheniramine maleate tablet mixing and preparation equipment provided by this utility model allows the pneumatic telescopic rod to extend the telescopic sleeve, and the fitting interface to fit and connect with the feed port or discharge port. The central top pressure rod simultaneously presses the sealing cover plate to slide inward to open the feed port or discharge port for loading and unloading operations. When the pneumatic telescopic rod retracts the telescopic sleeve, the fitting interface separates from the feed port or discharge port, and the sealing cover plate is reset by the traction sealing spring to re-close the feed port or discharge port. This not only ensures the sealing of the material during the mixing process and prevents external contamination, but also achieves automated operation through pneumatic control, simplifying the manual intervention process and improving processing efficiency and quality. Attached Figure Description

[0015] To more clearly illustrate the technical solutions in this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only for this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0016] Figure 1 This is a front structural diagram of an embodiment of the present utility model;

[0017] Figure 2 This is a schematic diagram of the structure of the V-shaped mixing cylinder according to an embodiment of the present invention;

[0018] Figure 3 This is a schematic diagram of the internal structure of the V-shaped mixing cylinder according to an embodiment of the present invention;

[0019] Figure 4 This is a schematic diagram of the main stirring shaft in an embodiment of the present invention;

[0020] Figure 5 This is a schematic diagram of the internal structure of the discharge mixing cylinder according to an embodiment of the present invention;

[0021] Figure 6 This is a schematic diagram of the structure of the telescopic sleeve according to an embodiment of the present utility model.

[0022] The diagram is marked as follows:

[0023] 1. Main frame; 101. Fixed support shaft; 102. Fixed bevel gear; 103. Stirring drive shaft; 104. Mixing motor; 2. V-shaped mixing cylinder; 201. Enclosed bushing; 202. First mixing chamber; 203. Second mixing chamber; 204. Feed inlet; 3. Discharge mixing cylinder; 301. Discharge port; 302. Central guide sleeve; 4. Sealing cover plate; 401. Central guide rod; 402. Traction sealing spring; 5. Main stirring shaft; 501. Mixing and stirring paddle; 502. Main drive bevel gear; 503. Linkage bevel gear; 6. Auxiliary stirring shaft; 601. Auxiliary drive gear; 602. Flexible scraper; 7. Feeding cylinder; 8. Discharging cylinder; 9. Telescopic sleeve; 901. Pneumatic telescopic rod; 902. Fitting interface; 903. Central top pressure rod. Detailed Implementation

[0024] To make the objectives, technical solutions, and advantages of this utility model clearer, the present utility model will be further described in detail below with reference to specific embodiments.

[0025] It should be noted that, unless otherwise defined, the technical or scientific terms used in this utility model should have the ordinary meaning understood by one of ordinary skill in the art to which this utility model pertains. The terms "first," "second," and similar terms used in this utility model do not indicate any order, quantity, or importance, but are merely used to distinguish different components. Terms such as "comprising" or "including" mean that the element or object preceding the word encompasses the elements or objects listed following the word and their equivalents, without excluding other elements or objects. Terms such as "connected" or "linked" are not limited to physical or mechanical connections, but can include electrical connections, whether direct or indirect. Terms such as "upper," "lower," "left," and "right" are used only to indicate relative positional relationships; when the absolute position of the described object changes, the relative positional relationship may also change accordingly.

[0026] like Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 , Figure 6 As shown, a mixing and preparation device for chlorpheniramine maleate tablets includes a main frame 1, a stirring drive shaft 103 horizontally arranged in the middle of the main frame 1, and a V-shaped mixing cylinder 2 connected to the outer end of the stirring drive shaft 103.

[0027] The V-shaped mixing cylinder 2 is symmetrically and inclinedly provided with a first mixing chamber 202 and a second mixing chamber 203. The top of the first mixing chamber 202 and the top of the second mixing chamber 203 are provided with inlets 204. The bottom of the V-shaped mixing cylinder 2 is provided with a discharge mixing cylinder 3, and the bottom of the discharge mixing cylinder 3 is provided with a discharge outlet 301.

[0028] A sealing cover plate 4 is fitted and slidably disposed on the inner side of the inlet 204 and the outlet 301. A traction sealing spring 402 is connected to the outer side of the sealing cover plate 4. The traction sealing spring 402 keeps the sealing cover plate 4 tightly fitted with the edges of the inlet 204 and the outlet 301 to keep them sealed.

[0029] The top left and right sides of the main frame 1 are symmetrically inclined with a feeding cylinder 7, and the bottom center of the main frame 1 is provided with a feeding cylinder 8. The outer ends of the feeding cylinder 7 and the feeding cylinder 8 are both nested and slidably provided with telescopic sleeves 9. The outer side of the telescopic sleeve 9 is connected with a pneumatic telescopic rod 901. The outer end of the telescopic sleeve 9 is provided with a fitting interface 902. The fitting interface 902 is configured to cooperate with the feed port 204 and the discharge port 301. The center pressure rod 903 is fixedly connected to the middle of the fitting interface 902.

[0030] In this embodiment, the chlorpheniramine maleate tablet mixing and preparation equipment is connected to a V-shaped mixing cylinder 2 via a stirring drive shaft 103 located in the middle of the main frame 1. A first mixing chamber 202 and a second mixing chamber 203 are symmetrically and inclinedly arranged inside the V-shaped mixing cylinder 2. These two mixing chambers have inlets 204 at the top and outlets 301 at the bottom. The raw materials to be mixed can be filled through the inlets 204. The stirring drive shaft 103, driven by a mixing motor 104 connected to its end, drives the V-shaped mixing cylinder 2 to rotate up and down, generating material convection and achieving mixing. Sealing covers 4 are slidably fitted inside both the inlets 204 and the outlets 301. Traction sealing springs 402 are connected to the outer sides of the sealing covers 4 to ensure a tight seal between the sealing covers 4 and the edges of the inlets 204 and the outlets 301. Furthermore, symmetrically inclined upper feed cylinders 7 are arranged on the left and right sides of the top of the main frame 1, and a lower feed cylinder 8 is arranged in the middle of the bottom. The upper feed cylinders 7 and the lower feed cylinder 8 can be connected to... An external quantitative conveying device has a telescopic sleeve 9 nested and slidingly mounted on the outer ends of the feeding cylinder 7 and the discharging cylinder 8. A pneumatic telescopic rod 901 is connected to the outer side of the telescopic sleeve 9. The outer end of the telescopic sleeve 9 has a fitting interface 902, and a central pressure rod 903 is fixedly connected in the middle. When the pneumatic telescopic rod 901 extends the telescopic sleeve 9, the fitting interface 902 engages with the inlet 204 or outlet 301, and the central pressure rod 903 simultaneously presses the sealing cover 4 inward to open the inlet 204 or outlet 301. The discharge port 301 is used for loading and unloading operations. When the pneumatic telescopic rod 901 drives the telescopic sleeve 9 to retract, the fitting interface 902 separates from the feed port 204 or the discharge port 301. The sealing cover plate 4 is reset by the traction sealing spring 402 to re-close the feed port 204 or the discharge port 301. This not only ensures the sealing of the material during the mixing process and prevents external contamination, but also realizes automated operation through pneumatic control, simplifies the process of manual intervention, and helps to improve processing efficiency and quality.

[0031] like Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 , Figure 6 As shown, preferably, a central guide sleeve 302 is connected to the middle of the outer side of both the feed inlet 204 and the discharge outlet 301 of the equipment. A central guide rod 401 is connected to the center of the outer side of the sealing cover plate 4. The central guide rod 401 is nested and slidably disposed inside the central guide sleeve 302. The sealing cover plate 4 is slidably connected to the central guide sleeve 302 through the central guide rod 401, ensuring accurate guidance and smooth movement of the sealing cover plate 4 when opening or closing the feed inlet 204 and the discharge outlet 301, and avoiding sealing problems caused by the misalignment of the sealing cover plate 4. When the pneumatic telescopic rod 901 drives the telescopic sleeve 9 to extend, the fitting interface 902 and the feed inlet... While the inlet 204 or outlet 301 is engaged, the central pressing rod 903 simultaneously presses the central guide rod 401, thereby driving the sealing cover 4 to slide inward to open the inlet 204 or outlet 301. The central guide rod 401 slides along the central guide sleeve 302, ensuring that the operation of the sealing cover 4 is more stable and accurate. When the pneumatic telescopic rod 901 drives the telescopic sleeve 9 to retract, the engagement interface 902 separates from the inlet 204 or outlet 301. The sealing cover 4 is re-closed by the traction of the traction sealing spring 402 and the guidance of the central guide rod 401 and the central guide sleeve 302.

[0032] like Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 , Figure 6 As shown, preferably, a fixed support shaft 101 and a stirring drive shaft 103 are respectively connected to the left and right sides of the V-shaped mixing cylinder 2 of the device. The fixed support shaft 101 and the stirring drive shaft 103 pass through the left and right side walls of the V-shaped mixing cylinder 2, respectively, and are coaxially arranged. The stirring drive shaft 103 is fixedly connected to the V-shaped mixing cylinder 2 to ensure that the V-shaped mixing cylinder 2 can rotate stably during the driving process. In particular, a closed bushing 201 is provided in the middle of the left side wall of the V-shaped mixing cylinder 2. The fixed support shaft 101 is rotatably connected to the V-shaped mixing cylinder 2 through the closed bushing 201. This not only ensures the sealing between the fixed support shaft 101 and the V-shaped mixing cylinder 2, but also makes the V-shaped mixing cylinder 2 more stable and reliable when rotating. When the stirring drive shaft 103 is activated, it will drive the entire V-shaped mixing cylinder 2 to rotate around the fixed support shaft 101 and the stirring drive shaft 103, thereby achieving full mixing of the internal materials, improving the stability of the V-shaped mixing cylinder 2 when rotating, and reducing the phenomenon of uneven mixing caused by vibration or imbalance.

[0033] like Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 , Figure 6 As shown, preferably, the equipment has a main stirring shaft 5 at the center of its discharge mixing cylinder 3. Multiple mixing paddles 501 are evenly arranged around the outside of the main stirring shaft 5. These mixing paddles 501 are rotatably connected to the discharge mixing cylinder 3 through the main stirring shaft 5. A main drive bevel gear 502 is provided at the top of the main stirring shaft 5, and a fixed bevel gear 102 is connected to the outer end of the fixed support shaft 101. The two are meshed with each other. When the V-shaped mixing cylinder 2 rotates, since the fixed support shaft 101 is fixed and the V-shaped mixing cylinder 2 rotates around it, this causes relative movement between the fixed bevel gear 102 and the main drive bevel gear 502, thereby driving the main drive bevel gear 502 to rotate, which in turn drives the main stirring shaft 5 and the mixing paddles 501 to rotate and mix the materials. This allows the materials to be stirred and mixed more thoroughly during the rotation of the V-shaped mixing cylinder 2, not only can the overall materials be turned over in a large area, but the bottom materials can also be stirred and mixed more finely by the main stirring shaft 5 and the mixing paddles 501 on it, ensuring the uniformity of the materials.

[0034] like Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 , Figure 6 As shown, preferably, the device is rotatably connected to the center of the first mixing chamber 202 and the second mixing chamber 203. A plurality of mixing paddles 501 are also evenly arranged around the outside of the secondary mixing shaft 6 to ensure that the material can be fully mixed. Each auxiliary stirring shaft 6 has an auxiliary drive gear 601 connected to its inner end, and a linkage bevel gear 503 is further connected above the main drive bevel gear 502. This design allows the linkage bevel gear 503 and the auxiliary drive gear 601 to mesh with each other. When the V-shaped mixing cylinder 2 rotates, the drive between the fixed bevel gear 102 and the main drive bevel gear 502 not only drives the main stirring shaft 5 and its mixing paddle 501 to stir, but also transmits power to the auxiliary drive gear 601 through the linkage bevel gear 503, thereby driving the auxiliary stirring shaft 6 and the mixing paddle 501 to rotate, realizing all-round material stirring, which greatly improves the mixing efficiency and uniformity. In addition, flexible scrapers 602 are also connected to the outer end of the mixing paddle 501. These flexible scrapers 602 are in close contact with the inner walls of the first mixing chamber 202, the second mixing chamber 203 and the discharge mixing cylinder 3, which not only helps to effectively clean the inner walls during the stirring process and prevent materials from sticking to the inner walls, but also improves the overall mixing effect.

[0035] The chlorpheniramine maleate tablet mixing and preparation equipment provided by this utility model features a pneumatic telescopic rod 901 that extends the telescopic sleeve 9, causing the fitting interface 902 to engage with the feed inlet 204 or the discharge outlet 301. Simultaneously, the central pressure rod 903 presses the sealing cover 4 inward to open the feed inlet 204 or the discharge outlet 301 for loading and unloading. When the pneumatic telescopic rod 901 retracts the telescopic sleeve 9, the fitting interface 902 separates from the feed inlet 204 or the discharge outlet 301. The sealing cover 4 is reset and re-closed by the traction sealing spring 402. This not only ensures the sealing of the material during the mixing process and prevents external contamination, but also achieves automated operation through pneumatic control, simplifying the manual intervention process and improving processing efficiency and quality.

[0036] Those skilled in the art should understand that the discussion of any of the above embodiments is merely exemplary and is not intended to imply that the scope of this utility model is limited to these examples; within the framework of this utility model, the technical features of the above embodiments or different embodiments can also be combined, the steps can be implemented in any order, and there are many other variations of the different aspects of this utility model as described above, which are not provided in the details for the sake of brevity. Any omissions, modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this utility model should be included within the protection scope of this utility model.

Claims

1. A mixing and preparation device for chlorpheniramine maleate tablets, comprising a main frame (1), characterized in that: A stirring drive shaft (103) is horizontally arranged in the middle of the main frame (1), and a V-shaped mixing cylinder (2) is connected to the outer end of the stirring drive shaft (103); The V-shaped mixing cylinder (2) is symmetrically and inclinedly provided with a first mixing chamber (202) and a second mixing chamber (203). The top of the first mixing chamber (202) and the second mixing chamber (203) are both provided with a feed inlet (204). The bottom of the V-shaped mixing cylinder (2) is provided with a discharge mixing cylinder (3), and the bottom of the discharge mixing cylinder (3) is provided with a discharge outlet (301). A sealing cover plate (4) is fitted and slidably provided on the inner side of the inlet (204) and the outlet (301). A traction sealing spring (402) is connected to the outer side of the sealing cover plate (4). The traction sealing spring (402) keeps the sealing cover plate (4) tightly fitted with the edges of the inlet (204) and the outlet (301) to maintain a closed seal. The top left and right sides of the main frame (1) are symmetrically inclined with upper cylinders (7) and the bottom middle of the main frame (1) is provided with lower cylinders (8). The outer ends of the upper cylinders (7) and lower cylinders (8) are nested and slidably provided with telescopic sleeves (9). The outer side of the telescopic sleeves (9) is connected with a pneumatic telescopic rod (901). The outer end of the telescopic sleeves (9) is provided with a fitting interface (902). The fitting interface (902) is configured to cooperate with the feed inlet (204) and the discharge outlet (301). The center pressure rod (903) is fixedly connected to the middle of the fitting interface (902).

2. The equipment for preparing chlorpheniramine maleate tablets according to claim 1, characterized in that, A central guide sleeve (302) is connected to the middle of the outer side of both the feed inlet (204) and the discharge outlet (301). A central guide rod (401) is connected to the center of the outer side of the sealing cover (4). The central guide rod (401) is nested and slidably disposed inside the central guide sleeve (302). The sealing cover (4) is slidably connected to the central guide sleeve (302) through the central guide rod (401).

3. The equipment for preparing chlorpheniramine maleate tablets according to claim 1, characterized in that, A fixed support shaft (101) and a stirring drive shaft (103) are respectively connected to the left and right sides of the V-shaped mixing cylinder (2). The fixed support shaft (101) and the stirring drive shaft (103) pass through the left and right side walls of the V-shaped mixing cylinder (2). The stirring drive shaft (103) is fixedly connected to the V-shaped mixing cylinder (2). A closed bushing (201) is provided in the middle of the left side wall of the V-shaped mixing cylinder (2). The fixed support shaft (101) is rotatably connected to the V-shaped mixing cylinder (2) through the closed bushing (201).

4. The equipment for preparing chlorpheniramine maleate tablets according to claim 3, characterized in that, A main stirring shaft (5) is provided at the center of the discharge mixing cylinder (3). Multiple mixing and stirring paddles (501) are evenly arranged around the outside of the main stirring shaft (5). The mixing and stirring paddles (501) are rotatably connected to the discharge mixing cylinder (3) through the main stirring shaft (5). A main drive bevel gear (502) is connected to the top of the main stirring shaft (5). A fixed bevel gear (102) is connected to the outer end of the fixed support shaft (101). The fixed bevel gear (102) and the main drive bevel gear (502) are meshed with each other.

5. The equipment for preparing chlorpheniramine maleate tablets according to claim 4, characterized in that, A secondary stirring shaft (6) is rotatably connected to the center of both the first mixing chamber (202) and the second mixing chamber (203). Multiple mixing and stirring paddles (501) are also evenly arranged around the outer side of the secondary stirring shaft (6). A secondary drive gear (601) is connected to the inner end of the secondary stirring shaft (6). A linkage bevel gear (503) is connected above the main drive bevel gear (502). The linkage bevel gear (503) and the secondary drive gear (601) are meshed with each other.

6. The equipment for preparing chlorpheniramine maleate tablets according to claim 5, characterized in that, The outer end of the mixing paddle (501) is connected to a flexible scraper (602), which is in close contact with the inner walls of the first mixing chamber (202), the second mixing chamber (203) and the discharge mixing cylinder (3).

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