A lactoferrin molecule equilibrium extraction reaction device
The improved lactoferrin molecular balance refining reaction device, with its scraping assembly and improved centrifuge tube connection structure, solves the problems of liquid adhesion and disassembly difficulties, enabling convenient disassembly and cleaning, and ensuring refining effect and equipment life.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- NANJING BAINAFU BIOTECHNOLOGY CO LTD
- Filing Date
- 2025-03-28
- Publication Date
- 2026-06-05
AI Technical Summary
In existing lactoferrin molecular equilibrium refining reaction devices, the liquid separated from the separation cylinder may adhere to the inner wall of the cylinder, affecting liquid discharge and centrifuge cylinder disassembly, leading to cleaning difficulties and affecting subsequent use.
A scraper assembly and an improved centrifuge drum connection structure were designed, including threaded connections and spring clamp structures, combined with a motor-driven scraper assembly and an electric slide rail, to enable easy disassembly and cleaning.
It improves the ease of installation and disassembly of centrifuge tubes, ensures smooth liquid discharge, extends equipment lifespan, and guarantees product quality.
Smart Images

Figure CN224321441U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of lactoferrin extraction and processing technology, specifically to a lactoferrin molecular equilibrium extraction reaction device. Background Technology
[0002] Lactoferrin, also known as lactoferrin, is a member of the transferrin family and is widely found in various secretions, such as milk, saliva, tears, and nasal secretions. Lactoferrin is also found in the secondary granules of polymorphonuclear leukocytes and is secreted by certain acinar cells. Lactoferrin can be purified or reconstituted from milk. In the process of separating lactoferrin, centrifugation, filtration, and other methods are commonly used.
[0003] In the prior art, such as the lactoferrin molecular equilibrium extraction reaction device described in Chinese Patent No. CN221016626U, there is a device shell, a discharge valve fixedly installed at the lower end of the device shell, a cover plate snapped onto the upper end of the device shell, a centrifuge cylinder placed inside the device shell and connected to the output end of a servo motor via a fixed column, a connecting block snapped onto the connecting column, and the connecting block, together with a connecting bolt, drives the cover plate at the upper end of the device shell to form a disassembly structure, and a limiting mechanism symmetrically arranged on the left and right sides of a mesh base plate. This lactoferrin molecular equilibrium extraction reaction device facilitates the centrifugation and purification of lactoferrin precipitates, facilitates thorough cleaning of the device interior to prevent residue, facilitates reuse, and, combined with the limiting mechanism, allows for disassembly of the mesh base plate and the centrifuge cylinder, facilitating the removal of the purified lactoferrin.
[0004] Although the aforementioned patent can centrifuge lactoferrin, it still has some problems. The liquid separated from the centrifuge tube may adhere to the inner wall of the tube due to its high viscosity, which may affect the normal discharge of the liquid from the tube. At the same time, the centrifuge tube is not easy to disassemble, which may affect the subsequent cleaning of the centrifuge tube. Therefore, this utility model provides a molecular equilibrium extraction reaction device for lactoferrin. Utility Model Content
[0005] To address the shortcomings of existing technologies, this invention provides a molecular equilibrium extraction reaction device for lactoferrin, which solves the problems that the liquid separated from the centrifuge cylinder may adhere to the inner wall of the cylinder due to its high viscosity, thus affecting the normal discharge of the liquid from the cylinder. In addition, the centrifuge cylinder is not easy to disassemble, which may affect the subsequent cleaning of the centrifuge cylinder.
[0006] To achieve the above objectives, this utility model is implemented through the following technical solution: a lactoferrin molecular equilibrium refining reaction device, comprising a cylinder, a cylinder cover being provided at the top of the cylinder, a centrifugal assembly being provided at the bottom of the cylinder cover, and a scraping assembly being provided on the inner wall of the cylinder;
[0007] The centrifugal assembly includes a feed rotary tube, a connecting pipe is threaded to the outer wall of the bottom end of the feed rotary tube, the bottom end of the connecting pipe is fixedly connected to a centrifugal cylinder, and an installation circular frame is fixedly installed on the outer wall of the feed rotary tube, and two arc-shaped clamps are provided on the inner wall of the installation circular frame.
[0008] The scraping assembly includes a rotating ring, a connecting plate is fixedly installed on the outer wall of the rotating ring, and a spiral scraper is fixedly installed on one end of the outer wall of the connecting plate. The spiral scraper is fitted against the inner wall of the cylinder.
[0009] Preferably, the feed rotary tube is rotatably mounted on the top of the cylinder cover and passes through the bottom of the cylinder cover. A second external gear ring is fixedly mounted on the outer wall of the feed rotary tube. A frame is fixedly mounted on the top of the cylinder cover. A second motor is fixedly mounted on the top of the frame. The output end of the second motor passes through the outer wall of the frame and is fixedly mounted with a second gear. The second gear meshes with the second external gear ring.
[0010] Preferably, four sliding rods slide through the outer wall of the mounting frame, and springs are sleeved on the outer walls of the four sliding rods. One end of the outer wall of each of the four sliding rods is fixedly connected to two arc-shaped clamps, one end of the outer wall of each of the four springs is fixedly connected to the outer walls of the two arc-shaped clamps, and the other end of the outer wall of each of the four springs is fixedly connected to the inner wall of the mounting frame.
[0011] Preferably, the rotating ring is rotatably mounted on the bottom end of the cylinder cover, the rotating ring is sleeved on the outer wall of the feed rotating tube, and a first external toothed ring is fixedly sleeved on the outer wall of the rotating ring.
[0012] Preferably, a first motor is fixedly installed at the top of the cylinder cover, the output shaft of the first motor passes through the bottom end of the cylinder cover, and a first gear is fixedly installed thereon, the first gear meshing with a first external gear ring.
[0013] Preferably, an electric slide rail is provided on one side of the outer wall of the cylinder, and a sliding connecting rod is provided at the output end of the electric slide rail. One end of the outer wall of the sliding connecting rod is fixedly connected to the cylinder cover. Beneficial effects
[0014] This invention provides a molecular equilibrium extraction reaction apparatus for lactoferrin. Compared with the prior art, it has the following advantages:
[0015] (1) In this lactoferrin molecular equilibrium refining reaction device, the centrifuge cylinder and the feed rotary tube are connected by threads. To improve the connection strength between the centrifuge cylinder and the feed rotary tube, when the centrifuge cylinder needs to be installed, the sliding rod is pulled to slide on the outer wall of the mounting frame, compressing or stretching the spring, thereby adjusting the distance between the two arc-shaped clamps. This allows the two arc-shaped clamps to fix the centrifuge cylinder, thus improving the connection strength between the centrifuge cylinder and the feed rotary tube. The arc-shaped clamp structure with sliding rod and spring, as well as the threaded connection between the centrifuge cylinder and the feed rotary tube, makes the centrifuge cylinder easy to disassemble and install. This facilitates cleaning and maintenance of the centrifuge cylinder after the refining process, ensuring its separation effect in subsequent use and extending the service life of the equipment.
[0016] (2) In this lactoferrin molecular equilibrium refining reaction device, when a lot of liquid adheres to the inner wall of the cylinder during centrifugation, the first motor at the top of the cylinder cover can be started. The first gear on its output shaft drives the first external gear ring fixedly sleeved on the outer wall of the rotating ring, causing the rotating ring to rotate. The rotating ring drives the spiral scraper to rotate along the inner wall of the cylinder through the connecting plate, scraping off the liquid adhering to the inner wall of the cylinder, promoting the discharge of liquid, ensuring that the liquid in the cylinder can be discharged normally, and avoiding the impact of liquid residue on subsequent refining operations and product quality. Attached Figure Description
[0017] Figure 1 This is a schematic diagram of the overall structure of this utility model;
[0018] Figure 2 This is a schematic cross-sectional view of the cylindrical body of this utility model;
[0019] Figure 3 This is a schematic diagram of the relevant structure of the cap of this utility model;
[0020] Figure 4 This is a schematic diagram of the relevant structure of the centrifuge component of this utility model;
[0021] Figure 5 This is a schematic diagram of the relevant structure of the centrifuge component of this utility model;
[0022] Figure 6 This is a schematic diagram of the relevant structure of the mounting circular frame of this utility model.
[0023] In the diagram: 1. Electric slide rail; 2. Cylinder body; 3. Sliding connecting rod; 4. Cylinder cover; 5. Scraper assembly; 51. Rotating ring; 52. First external gear ring; 53. Connecting plate; 54. Spiral scraper; 55. First motor; 56. First gear; 6. Centrifugal assembly; 61. Feed rotating tube; 62. Second external gear ring; 63. Frame; 64. Second gear; 65. Second motor; 66. Mounting circular frame; 67. Arc-shaped clamp; 68. Slide rod; 69. Connecting tube; 610. Centrifugal cylinder; 611. Spring. Detailed Implementation
[0024] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0025] This utility model provides two technical solutions:
[0026] Figures 1-6 The first embodiment is shown: a lactoferrin molecular equilibrium refining reaction device, including a cylinder 2, a cylinder cover 4 is provided at the top of the cylinder 2, a centrifugal component 6 is provided at the bottom of the cylinder cover 4, and a scraping component 5 is provided on the inner wall of the cylinder 2.
[0027] The centrifugal assembly 6 includes a feed rotary tube 61, and a connecting tube 69 is threaded to the outer wall of the bottom end of the feed rotary tube 61. The connecting tube 69 can be fixedly connected to the feed rotary tube 61 by rotating the connecting tube 69. The raw material can enter the centrifugal cylinder 610 through the feed rotary tube 61. The bottom end of the connecting tube 69 is fixedly connected to the centrifugal cylinder 610. A mounting circular frame 66 is fixedly installed on the outer wall of the feed rotary tube 61. Two arc-shaped clamps 67 are provided on the inner wall of the mounting circular frame 66.
[0028] The scraping assembly 5 includes a rotating ring 51, a connecting plate 53 is fixedly installed on the outer wall of the rotating ring 51, and a spiral scraper 54 is fixedly installed on one end of the outer wall of the connecting plate 53. The spiral scraper 54 is fitted against the inner wall of the cylinder 2. When the rotating ring 51 rotates, it can drive the spiral scraper 54 to rotate on the inner wall of the cylinder 2 through the connecting plate 53, thereby scraping off the liquid and other substances attached to the inner wall of the cylinder 2.
[0029] The feed rotary tube 61 is rotatably mounted on the top of the cylinder cover 4 and passes through the bottom of the cylinder cover 4. A second external gear ring 62 is fixedly mounted on the outer wall of the feed rotary tube 61. A frame 63 is fixedly mounted on the top of the cylinder cover 4. A second motor 65 is fixedly mounted on the top of the frame 63. The output end of the second motor 65 passes through the outer wall of the frame 63 and is fixedly mounted with a second gear 64. The second gear 64 meshes with the second external gear ring 62. The second motor 65 can drive the second gear 64 to rotate, thereby driving the second external gear ring 62 and the feed rotary tube 61 to rotate, which in turn drives the centrifuge cylinder 610 to rotate, thus centrifuging and purifying lactoferrin.
[0030] Four sliding rods 68 slide through the outer wall of the mounting frame 66. Each of the four sliding rods 68 has a spring 611 fitted onto its outer wall. One end of the outer wall of each sliding rod 68 is fixedly connected to two arc-shaped clamping plates 67. One end of the outer wall of each spring 611 is fixedly connected to the outer wall of the two arc-shaped clamping plates 67. The other end of the outer wall of each spring 611 is fixedly connected to the inner wall of the mounting frame 66. When the connecting pipe 69 is threadedly connected to the feed rotating pipe 61, the sliding rods 68 slide along the outer wall of the mounting frame 66, compressing or stretching the springs 611, thereby adjusting the distance between the two arc-shaped clamping plates 67. Then, under the elastic force of the springs 611, the two arc-shaped clamping plates 67 can fix the centrifuge cylinder 610, thus improving the connection strength between the centrifuge cylinder 610 and the feed rotating pipe 61.
[0031] Figures 1-6 The second embodiment is shown. The main difference from the first embodiment is that the rotating ring 51 is rotatably installed at the bottom end of the cylinder cover 4, the rotating ring 51 is sleeved on the outer wall of the feed rotating tube 61, and the outer wall of the rotating ring 51 is fixedly sleeved with the first external toothed ring 52.
[0032] A first motor 55 is fixedly installed on the top of the cylinder cover 4. The output shaft of the first motor 55 passes through the bottom of the cylinder cover 4 and is fixedly installed on a first gear 56. The first gear 56 and the first external gear ring 52 are meshed together.
[0033] An electric slide rail 1 is provided on one side of the outer wall of the cylinder 2. A sliding connecting rod 3 is provided at the output end of the electric slide rail 1. One end of the outer wall of the sliding connecting rod 3 is fixedly connected to the cylinder cover 4. The electric slide rail 1 is existing technology and can drive the cylinder cover 4 to move through the sliding connecting rod 3, so that the cylinder cover 4 can be raised, making it convenient to remove the centrifuge cylinder 610 from the cylinder 2, making it convenient to install or disassemble the centrifuge cylinder 610, and also making it convenient to clean the inner wall of the cylinder 2.
[0034] Furthermore, any content not described in detail in this specification is existing technology known to those skilled in the art.
[0035] During operation, the raw materials enter the device through the feed rotary tube 61. The second motor 65 at the top of the cylinder cover 4 is started, and the second gear 64 at its output end drives the second external gear ring 62 meshing with it, causing the feed rotary tube 61 to rotate. The connecting pipe 69 connected to the bottom end of the feed rotary tube 61 rotates synchronously with the centrifuge cylinder 610, centrifuging the lactoferrin mixture raw materials entering the centrifuge cylinder 610. When a lot of liquid adheres to the inner wall of the cylinder 2 during centrifugation, the first motor 55 at the top of the cylinder cover 4 can be started, and the first gear 56 on its output shaft drives the first external gear ring 52 fixedly sleeved on the outer wall of the rotating ring 51, causing the rotating ring 51 to rotate. The rotating ring 51 drives the spiral scraper 54 to rotate along the inner wall of the cylinder 2 via the connecting plate 53, scraping off the liquid adhering to the inner wall of the cylinder 2, promoting liquid discharge, and ensuring that the liquid in the cylinder 2 can be discharged normally, avoiding the impact of liquid residue on subsequent refining operations and product quality. After centrifugation is completed, the electric slide rail 1 is turned on, and the electric slide rail 1 drives the cylinder cover 4 to move upward via the sliding connecting rod 3, so that the centrifuge cylinder 610 at the bottom of the cylinder cover 4 is removed from the cylinder 2. Then, the slide rod 68 is pulled to remove the arc-shaped clamp 67 from the surface of the connecting tube 69. At this time, the centrifuge cylinder 610 can be removed by rotating the connecting tube 69. This makes it convenient to remove the lactoferrin inside the centrifuge cylinder 610 after the refining process is completed, and also facilitates the cleaning and maintenance of the centrifuge cylinder 610, ensuring its separation effect in subsequent use and extending the service life of the equipment.
[0036] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus.
[0037] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.
Claims
1. A lactoferrin molecular equilibrium refining reaction apparatus, comprising a cylinder (2), wherein a cylinder cap (4) is provided at the top of the cylinder (2), characterized in that: The bottom end of the cylinder cover (4) is provided with a centrifugal assembly (6), and the inner wall of the cylinder (2) is provided with a scraping assembly (5). The centrifugal assembly (6) includes a feed rotary tube (61), a connecting tube (69) is threaded to the outer wall of the bottom end of the feed rotary tube (61), the bottom end of the connecting tube (69) is fixedly connected to a centrifugal cylinder (610), an mounting circular frame (66) is fixedly installed on the outer wall of the feed rotary tube (61), and two arc-shaped clamps (67) are provided on the inner wall of the mounting circular frame (66). The scraping assembly (5) includes a rotating ring (51), a connecting plate (53) is fixedly installed on the outer wall of the rotating ring (51), and a spiral scraper (54) is fixedly installed on one end of the outer wall of the connecting plate (53). The spiral scraper (54) is fitted to the inner wall of the cylinder (2).
2. The apparatus for the molecular equilibrium extraction reaction of lactoferrin according to claim 1, characterized in that: The feed rotating tube (61) is rotatably installed on the top of the cylinder cover (4) and passes through the bottom of the cylinder cover (4). A second external gear ring (62) is fixedly installed on the outer wall of the feed rotating tube (61). A frame (63) is fixedly installed on the top of the cylinder cover (4). A second motor (65) is fixedly installed on the top of the frame (63). The output end of the second motor (65) passes through the outer wall of the frame (63) and is fixedly installed with a second gear (64). The second gear (64) meshes with the second external gear ring (62).
3. The apparatus for the molecular equilibrium extraction reaction of lactoferrin according to claim 1, characterized in that: Four sliding rods (68) slide through the outer wall of the mounting frame (66). Springs (611) are fitted on the outer walls of the four sliding rods (68). One end of the outer wall of the four sliding rods (68) is fixedly connected to two arc-shaped clamps (67). One end of the outer wall of the four springs (611) is fixedly connected to the outer walls of the two arc-shaped clamps (67). The other end of the outer wall of the four springs (611) is fixedly connected to the inner wall of the mounting frame (66).
4. The apparatus for the molecular equilibrium extraction reaction of lactoferrin according to claim 1, characterized in that: The rotating ring (51) is rotatably installed at the bottom end of the cylinder cover (4). The rotating ring (51) is sleeved on the outer wall of the feed rotating tube (61). The outer wall of the rotating ring (51) is fixedly sleeved with a first external toothed ring (52).
5. The apparatus for the molecular equilibrium extraction reaction of lactoferrin according to claim 4, characterized in that: The top of the cylinder cover (4) is fixedly installed with a first motor (55). The output shaft of the first motor (55) passes through the bottom end of the cylinder cover (4) and is fixedly installed with a first gear (56). The first gear (56) and the first external gear ring (52) are meshed.
6. The apparatus for the molecular equilibrium extraction reaction of lactoferrin according to claim 1, characterized in that: An electric slide rail (1) is provided on one side of the outer wall of the cylinder (2), and a sliding connecting rod (3) is provided at the output end of the electric slide rail (1). One end of the outer wall of the sliding connecting rod (3) is fixedly connected to the cylinder cover (4).