A multifunctional centrifuge tube processing device

Abstract

This utility model discloses a multifunctional centrifuge tube processing device, including a housing and an operation panel. The housing has a warm bath chamber connected to a drain pipe. A sealing mesh plate is provided above the warm bath chamber, and a transparent sealing frame is fixedly connected around the sealing mesh plate. A fixing column is fixedly connected to the bottom of the warm bath chamber, and a shaking assembly is connected to the upper end of the fixing column. A centrifuge motor connected to a tube rack assembly is fixedly installed at the upper end of the shaking assembly. The tube rack assembly includes a rotating shaft connected to the output end of the centrifuge motor, and a second rack plate with several insertion holes and a first rack plate with several placement holes, which are fixedly connected to the rotating shaft. A clamping sleeve for clamping centrifuge tubes is provided at the upper end of the insertion holes. This utility model can perform warm bath, shaking and mixing, and instantaneous centrifugation operations on centrifuge tubes on the same device. Experimenters do not need to frequently transfer centrifuge tubes between different devices, reducing the possibility of sample contamination and improving experimental efficiency and the accuracy of experimental results.

Description

Technical Field

[0001] This utility model relates to the field of centrifuge tube processing technology, and in particular to a multifunctional centrifuge tube processing device. Background Technology

[0002] Centrifugation technology has been widely used in biochemistry and molecular biology research. It is primarily used for the separation and preparation of various biological samples. When a biological sample suspension is placed in a centrifuge tube and rotated at high speed, the enormous centrifugal force causes the suspended microparticles to settle at a certain velocity, thus separating them from the solution. Currently, 1.5ml and 2ml centrifuge tubes are used extremely frequently in daily medical laboratory work. For example, in nucleic acid extraction experiments, samples need to be incubated at a specific temperature to promote cell lysis and nucleic acid release; afterwards, the lysis products need to be shaken to ensure sufficient contact between the reaction reagents; finally, a brief centrifugation is required to precipitate insoluble impurities and obtain a pure nucleic acid solution for subsequent detection.

[0003] Current methods for warming centrifuge tubes typically utilize water baths, metal baths, or similar equipment. After warming, the tubes are vortexed using a vortex mixer, followed by a short-term centrifugation process using a small centrifuge. Subsequent analysis is then performed after centrifugation. However, these devices are relatively simple in function, and each operates independently. Researchers must frequently transfer centrifuge tubes to different devices, which is not only time-consuming and labor-intensive, increasing the risk of sample contamination, but also can lead to inconsistencies in experimental procedures, affecting experimental efficiency and the accuracy of results. Utility Model Content

[0004] To address the technical problems of existing medical laboratory equipment having dispersed functions and the ease with which switching between different devices can lead to loose connections between experimental steps, affecting experimental efficiency and the accuracy of experimental results, this utility model provides the following technical solution.

[0005] This utility model discloses a multifunctional centrifuge tube processing device, comprising a housing and an operation screen located on one side of the housing. The housing has a warm bath chamber connected to a drain pipe. A sealing mesh plate is provided above the warm bath chamber. A transparent sealing frame is fixedly connected around the sealing mesh plate. A fixed column is fixedly connected to the bottom of the warm bath chamber. A vibration component is connected to the upper end of the fixed column. A centrifuge motor connected to a tube rack assembly is fixedly provided at the upper end of the vibration component. The tube rack assembly includes a rotating shaft connected to the output end of the centrifuge motor and a second rack plate with several insertion holes and a first rack plate with several placement holes, which are fixedly connected to the rotating shaft. A clamping sleeve for clamping centrifuge tubes is provided at the upper end of each insertion hole.

[0006] As a further technical solution, the clamping sleeve includes a tube body located above the insertion hole and a plurality of clamping bars located on the inner wall of the tube body.

[0007] As a further technical solution, the clamping bar includes a plurality of recessed portions spaced apart and a plurality of elastic protrusions located between two adjacent recessed portions.

[0008] As a further technical solution, the oscillation component includes a fixed plate fixedly connected to the fixed column and a support plate fixedly connected to the centrifugal motor. A plurality of support springs are fixedly connected between the fixed plate and the support plate. A vibration motor is fixedly mounted on the upper part of the fixed plate, and an eccentric wheel is connected to the output end of the vibration motor.

[0009] As a further technical solution, an elastic sealing sleeve is provided between the outer wall of the fixing plate and the outer wall of the support plate.

[0010] As a further technical solution, the bottom of the warm bath chamber is provided with a heating element and a temperature control component.

[0011] The beneficial effects of this invention are that the multifunctional centrifuge tube processing device integrates three functions: warming, shaking, and centrifugation. It allows for warming, shaking, and instantaneous centrifugation of centrifuge tubes on the same device, eliminating the need for frequent transfers between different devices, thus simplifying the experimental process and significantly shortening experimental time. Furthermore, reducing the number of centrifuge tube transfers effectively lowers the possibility of sample contamination during operation, improving experimental efficiency and the accuracy of results. Attached Figure Description

[0012] Figure 1 This is a schematic diagram of the structure of the multifunctional centrifuge tube processing device of this utility model;

[0013] Figure 2 This is a cross-sectional schematic diagram of the shell of the multifunctional centrifuge tube processing device of this utility model;

[0014] Figure 3 This is a schematic diagram of the top of the fixing column of the multifunctional centrifuge tube processing device of this utility model;

[0015] Figure 4 This is a schematic diagram of the oscillation component of the multifunctional centrifuge tube processing device of this utility model;

[0016] Figure 5 This is a cross-sectional schematic diagram of the tube rack assembly of the multifunctional centrifuge tube processing device of this utility model;

[0017] Figure 6 This is a schematic diagram of the clamping sleeve of the multifunctional centrifuge tube processing device of this utility model;

[0018] In the diagram: 1-Shell; 101-Warm bath chamber; 102-Drain pipe; 103-Sealing mesh plate; 2-Operating panel; 3-Transparent sealing frame; 4-Fixing column; 5-Oscillating component; 501-Fixing plate; 502-Support plate; 503-Elastic sealing sleeve; 504-Supporting spring; 505-Oscillating motor; 506-Eccentric wheel; 6-Centrifugal motor; 7-Pipe rack assembly; 701-Rotating shaft; 702-First rack plate; 703-Second rack plate; 704-Placement hole; 705-Insertion hole; 706-Reinforcing plate; 8-Clamping sleeve; 801-Pipe body; 802-Clamping strip; 803-Recessed part; 804-Elastic protrusion; 9-Heating element; 10-Temperature control component. Detailed Implementation

[0019] To make the objectives, technical solutions, and advantages of this utility model clearer, the present utility model will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present utility model and are not intended to limit the present utility model. It should be noted that, unless otherwise specified, the embodiments and features described herein can be combined with each other.

[0020] In the description of this utility model, it should be understood that the terms "upper" and "lower" are based on the orientation or positional relationship shown in the accompanying drawings and are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model. Furthermore, the terms "first," "second," etc., are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. In the description of this utility model, unless otherwise stated, "a plurality of" means two or more.

[0021] like Figure 1 and Figure 2 As shown, this utility model discloses a multifunctional centrifuge tube processing device, including a housing 1 and an operation screen 2 located on one side of the housing 1. The housing 1 has a hollow structure. The operation screen 2 is connected to a power supply and a control system, which is used to control the temperature control component 10, the oscillation component 5 and the centrifugal motor 6 described below. The control system adopts existing technology, and its specific control method will not be described in detail.

[0022] In a preferred embodiment, the housing 1 is provided with a warm bath chamber 101, and a drain pipe 102 is connected to the bottom of the warm bath chamber 101 to drain the water after the warm bath. In this case, the inner wall of the housing 1 is made of stainless steel, and the outer wall of the housing 1 is provided with a heat insulation layer to reduce heat loss within the warm bath chamber 101. The bottom of the warm bath chamber 101 is provided with a heating element 9 and a temperature control component 10. The heating element 9 can be a ceramic heating element, and a temperature sensor is provided inside the warm bath chamber 101. The temperature inside the warm bath chamber 101 is controlled in real time by the temperature control component 10, with a temperature control range from room temperature to 100°C and an accuracy of ±0.5°C, meeting the stringent temperature requirements of different experiments. For example, in the pre-denaturation step of a PCR reaction, the temperature can be precisely set at 95°C.

[0023] like Figure 2 , Figure 3 and Figure 4 As shown, in a preferred embodiment, a sealing mesh plate 103 is provided above the warm bath chamber 101. The sealing mesh plate 103 is used to seal and cover the warm bath chamber 101 from all sides, and water is supplied through the mesh of the sealing mesh plate 103. A transparent sealing frame 3 is fixedly connected around the sealing mesh plate 103. The transparent sealing frame 3 is made of acrylic material, and the lower edge of the transparent sealing frame 3 is sealed to the upper edge of the sealing mesh plate 103 to prevent water from overflowing during the warm bath. A fixing column 4 is fixedly connected to the bottom of the warm bath chamber 101. The upper end of the fixing column 4 passes through the sealing mesh plate 103, and the upper end of the fixing column 4 is connected to a shaking component 5 located above the sealing mesh plate 103. A centrifugal motor 6 is fixedly installed on the upper end of the shaking component 5. The output end of the centrifugal motor 6 is connected to a tube rack assembly 7, and multiple centrifugal tubes are inserted into the tube rack assembly 7. Thus, the shaking component 5 is used to shake and mix the centrifugal tubes.

[0024] In a preferred embodiment, the oscillation component 5 includes a fixed plate 501 fixedly connected to the upper end of the fixed column 4 and a support plate 502 fixedly connected to the centrifugal motor 6. The fixed plate 501 and the support plate 502 are arranged vertically. In this embodiment, both the fixed plate 501 and the support plate 502 are disc-shaped structures. Of course, the present invention does not particularly limit their specific shapes, and the fixed plate 501 and the support plate 502 can also be square plate structures. A plurality of support springs 504 are fixedly connected between the fixed plate 501 and the support plate 502. The support springs 504 are evenly distributed on the fixed plate 501 and can stably support the support plate 502. A vibration motor 505 is fixedly mounted on the upper part of the fixed plate 501. An eccentric wheel 506 is connected to the output end of the vibration motor 505. When the vibration motor 505 drives the eccentric wheel 506 to rotate, the eccentric wheel rotates repeatedly at a certain frequency at high speed, pushing and releasing the support plate 502. Combined with the frequent extension and retraction of the support spring 504, the centrifuge tubes placed on the tube rack assembly 7 can achieve efficient vibration and mixing.

[0025] To prevent water from corroding the vibratory motor 505 and eccentric wheel 506 during the hot bath, an elastic sealing sleeve 503 is provided between the outer walls of the fixed plate 501 and the support plate 502. The elastic sealing sleeve 503 can expand and contract with the vibration of the support plate 502, preventing water from corroding the vibratory motor 505 and eccentric wheel 506 without affecting the vibration.

[0026] like Figure 5 As shown, in a preferred embodiment, the tube rack assembly 7 includes a rotating shaft 701 connected to the output end of a centrifugal motor 6. The centrifugal motor 6 is a highly waterproof motor, and a braking device is provided on one side of the centrifugal motor 6. The braking device adopts an electromagnetic braking method, which can quickly stop the rotating shaft 701 after centrifugation, shortening the operation time. The rotating shaft 701 is fixedly connected to a second rack plate 703 and a first rack plate 702 distributed vertically. To ensure the stability of the second rack plate 703 and the first rack plate 702, a reinforcing plate 706 is fixedly connected between the second rack plate 703 and the first rack plate 702. The second rack plate 703 is provided with several insertion holes 705, which are used to accommodate centrifuge tubes with capacities of 1.5ml and 2ml. The first shelf plate 702 has a number of placement holes 704, the number of placement holes 704 matches the number of insertion holes 705, and is located directly below the insertion holes 705, for the lower end of the centrifuge tube to abut. The centrifuge tube can be inserted through the insertion hole 705 and abut against the placement hole 704. To ensure the stability of the centrifuge tube during the centrifugation process, the upper end of the insertion hole 705 is provided with a clamping sleeve 8 for clamping the centrifuge tube. The clamping sleeve 8 is fixedly connected to the upper end face of the second shelf plate 703, and the inner diameter of the clamping sleeve 8 matches the centrifuge tube.

[0027] like Figure 6 As shown, in a preferred embodiment, the clamping sleeve 8 includes a tube body 801 located above the insertion hole 705 and a plurality of clamping strips 802 located on the inner wall of the tube body 801. The clamping strips 802 are made of elastic material and can effectively clamp the centrifuge tube, ensuring the stability of the centrifuge tube during centrifugation. The clamping strips 802 include a plurality of recesses 803 spaced apart, and a plurality of elastic protrusions 804 are formed between two adjacent recesses 803. The plurality of elastic protrusions 804 can clamp the centrifuge tube in a stepped manner, further ensuring the stability of the centrifuge tube during centrifugation.

[0028] In use, water is first added to the warm bath chamber 101 from above the transparent sealing frame 3 via the sealing mesh plate 103. The control panel 2 is then activated to start the heating element 9 and the temperature control component 10, heating the water to the specified temperature. Then, centrifuge tubes are inserted one by one into the tube rack assembly 7. After a certain period of warm bathing, the drain pipe 102 is opened to drain the water from the warm bath chamber 101. After the water is drained, the oscillating component 5 is activated to oscillate and mix the centrifuge tubes on the tube rack assembly 7. After the centrifuge tubes are oscillated and mixed, the centrifuge motor 6 controls the tube rack assembly 7 to rotate at high speed to centrifuge the centrifuge tubes.

[0029] The preferred embodiments and examples of the present invention have been described in detail above with reference to the accompanying drawings. However, the present invention is not limited to the above embodiments and examples. Within the scope of knowledge possessed by those skilled in the art, various changes or equivalent substitutions can be made without departing from the concept of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed herein, and all embodiments falling within the scope of the claims of this application are within the scope of protection of the present invention.

Claims

1. A multifunctional centrifuge tube processing device, comprising a housing (1) and an operation screen (2) located on one side of the housing (1), characterized in that: The housing (1) is provided with a warm bath chamber (101) connected to a drain pipe (102). A sealing mesh plate (103) is provided above the warm bath chamber (101). A transparent sealing frame (3) is fixedly connected around the sealing mesh plate (103). A fixed column (4) is fixedly connected to the bottom of the warm bath chamber (101). A vibration component (5) is connected to the upper end of the fixed column (4). A centrifugal motor (6) connected to a tube rack assembly (7) is fixedly provided at the upper end of the vibration component (5). The tube rack assembly (7) includes a rotating shaft (701) connected to the output end of the centrifugal motor (6) and a second frame plate (703) with several insertion holes (705) and a first frame plate (702) with several placement holes (704) fixedly connected to the rotating shaft (701). A clamping sleeve (8) for clamping centrifugal tubes is provided at the upper end of the insertion hole (705).

2. The multifunctional centrifuge tube processing device according to claim 1, characterized in that: The clamping sleeve (8) includes a tube body (801) located above the insertion hole (705) and a plurality of clamping bars (802) located on the inner wall of the tube body (801).

3. The multifunctional centrifuge tube processing device according to claim 2, characterized in that: The clamping bar (802) includes a plurality of recesses (803) spaced apart and a plurality of elastic protrusions (804) located between two adjacent recesses (803).

4. The multifunctional centrifuge tube processing device according to claim 1, characterized in that: The oscillating component (5) includes a fixed plate (501) fixedly connected to the fixed column (4) and a support plate (502) fixedly connected to the centrifugal motor (6). A plurality of support springs (504) are fixedly connected between the fixed plate (501) and the support plate (502). A vibration motor (505) is fixedly mounted on the upper part of the fixed plate (501). An eccentric wheel (506) is connected to the output end of the vibration motor (505).

5. The multifunctional centrifuge tube processing device according to claim 4, characterized in that: An elastic sealing sleeve (503) is provided between the outer walls of the fixing plate (501) and the support plate (502).

6. The multifunctional centrifuge tube processing device according to claim 1, characterized in that: The bottom of the warm bath chamber (101) is provided with a heating element (9) and a temperature control component (10).

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