A radiopharmaceutical labeling purification apparatus

Abstract

The utility model discloses a radioactive drug marking purification equipment belongs to the medicine purification technical field, and its technical scheme main points include the purification equipment ontology, the surface welding has the heat abstractor at the bottom of the both sides of purification equipment ontology, the surface welding has the auxiliary mechanism at the top of the both sides of purification equipment ontology, and the heat abstractor forms the closed loop circuit through left and right two sides circulation pipe and distribution pipe, and the cooperation circulation pump drives the cooling liquid flow, realizes the uniform heat absorption to the bottom of purification equipment ontology, avoids the local overheating, and the flow path of cooling liquid is prolonged in the liquid storage tank's flow guide inclined plate and the water inlet, and the contact area with the heat absorption rod is increased, and the heat exchange efficiency is strengthened, and the semiconductor refrigeration board in the refrigeration box can reduce the cooling liquid temperature fast, and temperature sensor real -time feedback water temperature, realizes the intelligent temperature control through PLC controller, ensures that the cooling liquid is always in the low temperature state, and the heat of semiconductor refrigeration board produces is discharged through the exhaust fan through the exhaust hole, avoids the heat accumulation influence refrigeration efficiency.

Description

Technical Field

[0001] This utility model relates to the field of drug purification technology, and in particular to a radiopharmaceutical labeling and purification device. Background Technology

[0002] Radiopharmaceutical labeling and purification equipment is a specialized device used in the preparation of radiopharmaceuticals to separate, purify, and control the quality of labeled compounds. Its core function is to ensure the safety, efficacy, and stability of radiopharmaceuticals.

[0003] To address the aforementioned issues, existing patents have provided solutions. However, most existing radiopharmaceutical labeling and purification equipment directly uses the casing for heat dissipation, lacking a structure for rapid cooling of the casing. This causes the casing temperature to rise continuously during long-term operation or high-load work, which not only affects the performance of internal electronic components and reaction components, such as slowing down the operating speed and reducing the stability of electronic components, but may also interfere with the rate and purity of the labeling reaction, thereby affecting the production efficiency and quality of radiopharmaceuticals.

[0004] Therefore, a radiopharmaceutical labeling and purification device is proposed. Utility Model Content

[0005] The purpose of this invention is to provide a radiopharmaceutical labeling and purification device that solves the problem that most existing radiopharmaceutical labeling and purification devices directly use the shell for heat dissipation, lacking a structure for rapid cooling of the shell. This causes the shell temperature to rise continuously during long-term operation or high-load work, which not only affects the performance of the internal electronic components and reaction components, such as slowing down the operating speed and reducing the stability of electronic components, but may also interfere with the rate and purity of the labeling reaction, thereby affecting the production efficiency and quality of radiopharmaceuticals.

[0006] To achieve the above objectives, the present invention provides the following technical solution: a radiopharmaceutical labeling and purification device, comprising a purification device body, wherein heat dissipation mechanisms are welded to the bottom surfaces on both sides of the purification device body, and auxiliary mechanisms are welded to the top surfaces on both sides of the purification device body;

[0007] The heat dissipation mechanism includes a heat absorption plate, a circulation pipe, a storage tank, a circulation pump, a distribution pipe, a water pump, two guide plates, several water inlets, several heat absorption rods, a cooling box, several semiconductor cooling plates, two exhaust fans, exhaust vents, a temperature sensor, and a PLC controller. The heat absorption plate is welded to the bottom surfaces of both sides of the purification equipment body. The circulation pipe is welded to the inside of the heat absorption plate. The top of the left circulation pipe is fixedly connected to the left side of the distribution pipe, the bottom of the left circulation pipe is fixedly connected to the left side of the distribution pipe, the top of the left circulation pipe is fixedly connected to the top of the left side of the storage tank, and the bottom of the right circulation pipe is fixedly connected to the right side of the distribution pipe.

[0008] Preferably, the top of the right-side circulation pipe is fixedly connected to the top right side of the storage tank, which is fixedly connected to the rear side of the purification equipment body. The circulation pump is installed on top of the storage tank, the distribution pipe is fixedly connected to the rear side of the circulation pump, and the water suction pipe is fixedly connected to the front side of the circulation pump. The bottom of the water suction pipe penetrates the storage tank and extends to the inner side of the bottom of the storage tank. The guide plates are respectively welded to the top and bottom of the inner side of the storage tank. The drain holes are respectively opened on the right side of the top guide plate and the left side of the bottom guide plate. The heat absorption rods are respectively welded to the top guide plate. The bottom and the top of the bottom guide plate are connected to the refrigeration box welded to the inside of the liquid storage tank. The side of the heat absorption rod away from the top guide plate and the bottom guide plate is welded to the surface of the refrigeration box. The semiconductor refrigeration plate is welded to the top and bottom of the inside of the refrigeration box, respectively. The exhaust fan is installed on both sides of the right side of the refrigeration box. The exhaust vents are opened on both sides of the right side of the liquid storage tank. The temperature sensor is installed on the right side of the top of the liquid storage tank. The detection end of the temperature sensor at the bottom penetrates through and extends to the inside of the liquid storage tank. The PLC controller is installed on the surface of the rear side of the liquid storage tank.

[0009] Preferably, the auxiliary mechanism includes several heat dissipation plates, a protective shell, several magnetic cooling plates, a mounting groove, and a ventilation fan, wherein the heat dissipation plates are welded to the top surfaces of both sides of the purification equipment body.

[0010] Preferably, the protective shell is welded to the top surfaces of both sides of the purification device body, and the magnetic cooling plate is welded to the inner wall of the protective shell.

[0011] Preferably, the mounting slots are formed at the top and bottom of the rear side of the protective shell, and the ventilation fan is installed inside the mounting slots.

[0012] Preferably, the heat sink has heat dissipation holes on its inner side, and the surface of the heat sink is coated with thermal grease.

[0013] Preferably, a protective plate is welded to the rear side of the protective shell, and a dust filter is welded to the inner side of the protective plate.

[0014] Preferably, a filling tube is fixedly connected to the left side of the liquid storage tank, and a stopper cap is snapped into the top of the inner side of the filling tube.

[0015] Compared with the prior art, the beneficial effects of this utility model are:

[0016] 1. The heat dissipation mechanism of this application forms a closed loop through the left and right circulation pipes and distribution pipes, and works with the circulation pump to drive the flow of coolant, so as to achieve uniform heat absorption at the bottom of the purification equipment body and avoid local overheating. The guide plate and drain hole in the liquid storage tank extend the flow path of the coolant, increase the contact area with the heat absorption rod, and enhance the heat exchange efficiency. The semiconductor refrigeration plate in the refrigeration box can quickly reduce the temperature of the coolant. The temperature sensor provides real-time feedback of the water temperature, and the PLC controller realizes intelligent temperature control to ensure that the coolant is always at a low temperature. The heat generated by the semiconductor refrigeration plate is discharged through the exhaust fan and exhaust hole to avoid heat accumulation affecting the refrigeration efficiency.

[0017] 2. The auxiliary mechanism of this application achieves compressor-free cooling by utilizing the magnetocaloric effect through a magnetic cooling plate. Compared with traditional compressor cooling, it has the advantages of low noise, low energy consumption, and long lifespan, making it particularly suitable for medical equipment scenarios with high environmental requirements. The heat sink expands the heat dissipation area through surface heat dissipation holes and thermal grease, while the magnetic cooling plate further reduces the ambient air temperature, forming a dual effect of active cooling and passive heat dissipation. The ventilation fan inside the protective shell accelerates airflow and quickly dissipates heat. Attached Figure Description

[0018] Figure 1 This is an overall structural diagram of the radiopharmaceutical labeling and purification device of this utility model;

[0019] Figure 2 This is a schematic diagram of the structure of the heat absorber plate of this utility model;

[0020] Figure 3 This is a schematic diagram of the structure of the guide plate of this utility model;

[0021] Figure 4 This is a schematic diagram of the auxiliary mechanism of this utility model;

[0022] Figure 5 This is a schematic diagram of the structure of the protective plate of this utility model.

[0023] In the diagram, 1. Purification equipment body; 2. Heat dissipation mechanism; 201. Heat absorption plate; 202. Circulation pipe; 203. Liquid storage tank; 204. Circulation pump; 205. Distribution pipe; 206. Water pumping pipe; 207. Flow guide plate; 208. Drain hole; 209. Heat absorption rod; 210. Refrigeration box; 211. Semiconductor refrigeration plate; 212. Exhaust fan; 213. Exhaust vent; 214. Temperature sensor; 215. PLC controller; 3. Auxiliary mechanism; 301. Heat dissipation plate; 302. Protective shell; 303. Magnetic refrigeration plate; 304. Mounting slot; 305. Ventilation fan; 4. Heat dissipation hole; 5. Protective plate; 6. Dust filter; 7. Filling pipe; 8. Plug. Detailed Implementation

[0024] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0025] Please see Figure 1-5 The present invention provides the following technical solution:

[0026] A radiopharmaceutical labeling and purification device includes a purification device body 1, heat dissipation mechanisms 2 welded to the bottom surfaces on both sides of the purification device body 1, and auxiliary mechanisms 3 welded to the top surfaces on both sides of the purification device body 1.

[0027] The heat dissipation mechanism 2 includes a heat absorption plate 201, a circulation pipe 202, a liquid storage tank 203, a circulation pump 204, a distribution pipe 205, a water pump 206, two guide plates 207, several water inlets 208, several heat absorption rods 209, a cooling box 210, several semiconductor cooling plates 211, two exhaust fans 212, an exhaust vent 213, a temperature sensor 214, and a PLC controller 215. The heat absorption plate 201 is welded to the bottom surfaces of both sides of the purification equipment body 1. The circulation pipe 202 is welded to the inner side of the heat absorption plate 201. The top of the left circulation pipe 202 is fixedly connected to the left side of the distribution pipe 205, the bottom of the left circulation pipe 202 is fixedly connected to the left side of the distribution pipe 205, the top of the left circulation pipe 202 is fixedly connected to the top of the left side of the liquid storage tank 203, and the bottom of the right circulation pipe 202 is fixedly connected to the right side of the distribution pipe 205.

[0028] In this embodiment: the purification device body 1 can be used to label and purify radiopharmaceuticals, while also supporting and limiting the heat dissipation mechanism 2 and auxiliary mechanism 3. The heat absorption plate 201 can quickly absorb the heat generated during device operation and transfer it to the inner circulation pipe 202, achieving efficient heat dissipation at the bottom of the device. Driven by the circulation pump 204, the coolant flows in the circulation pipe 202, continuously carrying away the heat absorbed by the heat absorption plate 201, ensuring timely heat transfer and maintaining a stable temperature at the bottom of the device. The storage tank 203 stores coolant, providing a stable coolant source for the circulation system. The circulation pump 204 can pump the stored coolant... The coolant in tank 203 is extracted and transported to circulation pipe 202 through distribution pipe 205 to ensure continuous coolant flow. Distribution pipe 205 distributes coolant to the left and right circulation pipes 202, allowing the coolant to flow evenly across heat absorber plate 201. Water extraction pipe 206 extracts coolant from the bottom of tank 203 and transports it to circulation pump 204. Two guide plates 207 are installed inside tank 203 to extend the flow path of the coolant, increase the contact time and area between the coolant and heat absorber rod 209, enhance heat exchange, and allow the coolant to dissipate heat more effectively. Drain hole 208 assists in the guide plate flow. Inclined plate 207 guides the coolant to flow along a specific path, ensuring orderly circulation of the coolant within the reservoir 203 and further improving heat exchange efficiency. Heat-absorbing rod 209 connects the guide plate 207 to the cooling box 210, transferring the heat carried by the coolant to the cooling box 210, accelerating the cooling process. The cooling box 210 rapidly cools the heat transferred by the heat-absorbing rod 209, lowering the coolant temperature. Simultaneously, it supports and limits the semiconductor cooling plate 211 and the exhaust fan 212. The semiconductor cooling plate 211 utilizes the Peltier effect to quickly absorb heat from the cooling box 210, achieving efficient cooling of the coolant. The equipment operates at the required temperature. The cooling intensity is adjusted by the PLC controller 215. The exhaust fan 212 promptly dissipates the heat generated by the semiconductor cooling plate 211, preventing heat accumulation in the liquid storage tank 203. The exhaust vent 213 works in conjunction with the exhaust fan 212 to provide a channel for heat dissipation. The temperature sensor 214 monitors the temperature of the coolant in the liquid storage tank 203 in real time and feeds the data back to the PLC controller 215. Based on the temperature data fed back by the temperature sensor 214, the PLC controller 215 automatically adjusts the cooling intensity of the semiconductor cooling plate 211 and the speed of the circulation pump 204 to ensure that the coolant temperature is always kept within a suitable range.

[0029] Specifically, such as Figure 2 , Figure 3As shown, the top of the right-side circulation pipe 202 is fixedly connected to the top right side of the storage tank 203. The storage tank 203 is fixedly connected to the rear side of the purification equipment body 1. The circulation pump 204 is installed on the top of the storage tank 203. The distribution pipe 205 is fixedly connected to the rear side of the circulation pump 204. The water suction pipe 206 is fixedly connected to the front side of the circulation pump 204. The bottom of the water suction pipe 206 passes through the storage tank 203 and extends to the inner side of the bottom of the storage tank 203. The guide plates 207 are welded to the top and bottom of the inner side of the storage tank 203, respectively. The drain holes 208 are respectively opened on the right side of the top guide plate 207 and the left side of the bottom guide plate 207. The heat absorption rod 209 is welded to the bottom of the top guide plate 207. The top of the top and bottom guide ramps 207, the refrigeration box 210 is welded to the inside of the liquid storage tank 203, the heat absorption rod 209 is welded to the surface of the refrigeration box 210 on the side away from the top guide ramps 207 and the bottom guide ramps 207, the semiconductor refrigeration plate 211 is welded to the top and bottom of the inside of the refrigeration box 210 respectively, the exhaust fan 212 is installed on both sides of the right side of the refrigeration box 210, the exhaust vent 213 is opened on both sides of the right side of the liquid storage tank 203, the temperature sensor 214 is installed on the right side of the top of the liquid storage tank 203, the detection end of the bottom of the temperature sensor 214 penetrates and extends to the inside of the liquid storage tank 203, and the PLC controller 215 is installed on the surface of the rear side of the liquid storage tank 203.

[0030] Specifically, such as Figure 4 As shown, the auxiliary mechanism 3 includes several heat dissipation plates 301, a protective shell 302, several magnetic cooling plates 303, a mounting groove 304, and a ventilation fan 305. The heat dissipation plates 301 are welded to the top surfaces of both sides of the purification equipment body 1.

[0031] Specifically, such as Figure 4 As shown, the protective shell 302 is welded to the top surfaces of both sides of the purification equipment body 1, and the magnetic cooling plate 303 is welded to the inner wall of the protective shell 302.

[0032] In this embodiment: by setting a heat dissipation plate 301, the heat dissipation area of ​​the top of the purification equipment body 1 is increased. The protective shell 302 protects the internal heat dissipation plate 301, magnetic cooling plate 303 and ventilation fan 305, preventing external dust and debris from entering. At the same time, it provides a stable working environment for the magnetic cooling plate 303. The magnetic cooling plate 303 uses the magnetocaloric effect to achieve cooling, providing an active cooling function for the top of the equipment. Combined with the passive heat dissipation of the heat dissipation plate 301, it quickly reduces the temperature of the top of the equipment and has the advantages of no noise, no refrigerant pollution and low energy consumption, which meets the special requirements of radiopharmaceutical preparation equipment. The mounting slot 304 provides an installation position for the ventilation fan 305, ensuring that the ventilation fan 305 is installed firmly and facilitating the installation, disassembly and maintenance of the ventilation fan 305. The ventilation fan 305 accelerates the air flow inside the protective shell 302, quickly transferring the cold energy generated by the magnetic cooling plate 303 to the top of the equipment, while dissipating the heat from the top of the equipment, enhancing the auxiliary heat dissipation effect and improving the overall heat dissipation performance of the equipment.

[0033] Specifically, such as Figure 4 As shown, mounting slots 304 are formed at the top and bottom of the rear side of the protective shell 302, and ventilation fans 305 are installed inside the mounting slots 304.

[0034] Specifically, such as Figure 4 As shown, heat dissipation holes 4 are provided on the inner side of the heat sink 301, and the surface of the heat sink 301 is coated with thermal grease.

[0035] In this embodiment: by setting heat dissipation holes 4, the contact area between the heat sink 301 and the air is increased, air convection is promoted, heat dissipation is accelerated, and the heat dissipation efficiency of the heat sink 301 is improved. By setting thermal grease, the heat dissipation efficiency of the heat sink 301 for the device is further improved.

[0036] Specifically, such as Figure 5 As shown, a protective plate 5 is welded to the rear side of the protective shell 302, and a dust filter 6 is welded to the inner side of the protective plate 5.

[0037] Specifically, such as Figure 5 As shown, a filling tube 7 is fixedly connected to the left side of the liquid storage tank 203, and a stopper cap 8 is snapped into the top of the inner side of the filling tube 7.

[0038] In this embodiment: by setting the protective plate 5, the dust filter 6 can be supported and limited. By setting the dust filter 6, dust and impurities in the air are filtered to ensure that the air entering the protective shell 302 is clean, maintain the cleanliness of the equipment, and prevent dust accumulation from affecting the heat dissipation effect and normal operation of the equipment. By setting the filling pipe 7, coolant can be added to the liquid storage tank 203, which is convenient for operators to replenish coolant. By setting the plug 8, the filling pipe 7 is sealed to prevent coolant leakage and dust from entering the liquid storage tank 203, ensuring the cleanliness of the coolant and the sealing of the heat dissipation system.

[0039] Working Principle: First, the operator performs radiopharmaceutical labeling and purification using the purification equipment body 1. During operation, the heat generated by the purification equipment body 1 is rapidly absorbed by the heat absorber plate 201 and transferred to the inner circulation pipe 202. Next, the operator starts the circulation pump 204 via the PLC controller 215. The circulation pump 204 draws coolant from the storage tank 203 and delivers it to the distribution pipe 205 via the water suction pipe 206. The distribution pipe 205 then evenly distributes the coolant to the left and right circulation pipes 202, allowing the coolant to flow within the circulation pipes 202 and continuously carry away the heat absorbed by the heat absorber plate 201, achieving initial heat dissipation at the bottom of the equipment. Then, the coolant carrying heat flows back to the storage tank 203. Inside the storage tank 203, two upper and lower guide plates 207, along with the drain hole 208, extend the flow path of the coolant, increasing its contact time and area with the heat absorber rod 209, thus enhancing the heat exchange effect. The heat absorber rod 209 transfers the heat of the coolant to the cooling box 210. Subsequently, the semiconductor cooling plate 211 inside the cooling box 210 utilizes the Peltier effect to quickly absorb heat and efficiently cool the coolant. Simultaneously, the exhaust fan 212 promptly discharges the heat generated by the semiconductor cooling plate 211 through the exhaust vent 213, preventing heat accumulation. During this process, the temperature sensor 214 monitors the temperature of the coolant in the storage tank 203 in real time and feeds the data back to the PLC controller 215. The PLC controller 215 automatically adjusts the cooling intensity of the semiconductor cooling plate 211 and the speed of the circulation pump 204 based on the feedback data to ensure that the coolant temperature is always kept within a suitable range. At the same time, the PLC controller 215 controls the magnetic cooling plate 303 to start. The magnetic cooling plate 303 utilizes the magnetocaloric effect to achieve active cooling, which, combined with the passive heat dissipation of the heat sink 301, finally, the ventilation fan 305 accelerates the airflow inside the protective shell 302, transferring the cold energy generated by the magnetic cooling plate 303 to the top of the equipment, dissipating heat, and maintaining the purification equipment body 1 at a suitable temperature for operation.

[0040] The above are merely preferred embodiments of the present utility model and are not intended to limit the present utility model. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A radiopharmaceutical labeling and purification device, comprising a purification device body (1), characterized in that: Heat dissipation mechanisms (2) are welded to the bottom surfaces on both sides of the purification device body (1), and auxiliary mechanisms (3) are welded to the top surfaces on both sides of the purification device body (1). The heat dissipation mechanism (2) includes a heat absorption plate (201), a circulation pipe (202), a liquid storage tank (203), a circulation pump (204), a distribution pipe (205), a water pumping pipe (206), two guide plates (207), several drain holes (208), several heat absorption rods (209), a cooling box (210), several semiconductor cooling plates (211), two exhaust fans (212), an exhaust vent (213), a temperature sensor (214), and a PLC controller (215). 201) Welded to the bottom surfaces of both sides of the purification equipment body (1), the circulation pipe (202) is welded to the inside of the heat absorption plate (201), the top of the left circulation pipe (202) is fixedly connected to the left side of the distribution pipe (205), the bottom of the left circulation pipe (202) is fixedly connected to the left side of the distribution pipe (205), the top of the left circulation pipe (202) is fixedly connected to the top of the left side of the liquid storage tank (203), and the bottom of the right circulation pipe (202) is fixedly connected to the right side of the distribution pipe (205).

2. The radiopharmaceutical labeling and purification device according to claim 1, characterized in that: The top of the right circulation pipe (202) is fixedly connected to the top right side of the storage tank (203). The storage tank (203) is fixedly connected to the rear side of the purification equipment body (1). The circulation pump (204) is installed on the top of the storage tank (203). The distribution pipe (205) is fixedly connected to the rear side of the circulation pump (204). The water suction pipe (206) is fixedly connected to the front side of the circulation pump (204). The bottom of the water suction pipe (206) penetrates the storage tank (203) and extends to the inner side of the bottom of the storage tank (203). The guide plates (207) are welded to the top and bottom of the inner side of the storage tank (203). The drain holes (208) are respectively opened on the right side of the top guide plate (207) and the left side of the bottom guide plate (207). The heat absorption rod (209) is welded to the bottom of the top guide plate (207) and the bottom guide plate (207). The top of the bottom guide plate (207), the refrigeration box (210) is welded to the inside of the liquid storage tank (203), the heat absorption rod (209) is welded to the surface of the refrigeration box (210) on the side away from the top guide plate (207) and the bottom guide plate (207), the semiconductor refrigeration plate (211) is welded to the top and bottom of the inside of the refrigeration box (210) respectively, the exhaust fan (212) is installed on both sides of the right side of the refrigeration box (210), the exhaust hole (213) is opened on both sides of the right side of the liquid storage tank (203), the temperature sensor (214) is installed on the right side of the top of the liquid storage tank (203), the detection end of the bottom of the temperature sensor (214) penetrates and extends to the inside of the liquid storage tank (203), and the PLC controller (215) is installed on the surface of the rear side of the liquid storage tank (203).

3. The radiopharmaceutical labeling and purification device according to claim 1, characterized in that: The auxiliary mechanism (3) includes several heat dissipation plates (301), a protective shell (302), several magnetic cooling plates (303), a mounting groove (304), and a ventilation fan (305). The heat dissipation plates (301) are welded to the top surfaces of both sides of the purification equipment body (1).

4. The radiopharmaceutical labeling and purification apparatus according to claim 3, characterized in that: The protective shell (302) is welded to the top surfaces of both sides of the purification equipment body (1), and the magnetic cooling plate (303) is welded to the inner wall of the protective shell (302).

5. The radiopharmaceutical labeling and purification apparatus according to claim 3, characterized in that: The mounting groove (304) is formed at the top and bottom of the rear side of the protective shell (302), and the ventilation fan (305) is installed inside the mounting groove (304).

6. The radiopharmaceutical labeling and purification apparatus according to claim 3, characterized in that: The heat sink (301) has heat dissipation holes (4) on its inner side, and the surface of the heat sink (301) is coated with heat dissipation grease.

7. The radiopharmaceutical labeling and purification apparatus according to claim 3, characterized in that: A protective plate (5) is welded to the rear side of the protective shell (302), and a dust filter (6) is welded to the inner side of the protective plate (5).

8. The radiopharmaceutical labeling and purification apparatus according to claim 1, characterized in that: A filling tube (7) is fixedly connected to the left side of the liquid storage tank (203), and a cap (8) is snapped into the top of the inner side of the filling tube (7).

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