A solid phase extraction rapid separation device

Abstract

This utility model relates to the field of solid-phase extraction and discloses a rapid separation device for solid-phase extraction, including a vacuum tank. A crossbar is rotatably connected to the side of the vacuum tank, and a knob is fixedly connected to the side of the crossbar. A sealing gasket is fitted around the outer periphery of the crossbar, and a retaining ring is fitted around the outside of the crossbar. A spring is fitted around the side of the retaining ring. A clamp is fixedly connected to the left side of the crossbar, and a flow guide plate is installed on the side of the clamp. A bracket is fixedly connected inside the vacuum tank. In this utility model, rotating the knob drives the crossbar, which in turn drives the clamp, thereby driving the flow guide plate. Rotating the knob causes the flow guide plate to flip downwards, passing through the guide channel. The flow guide plate slides downwards and, upon reaching a certain height, is supported by the bracket, thus solving the problem of not having to remove the extraction column tray after each extraction of waste liquid.

Description

Technical Field

[0001] This utility model relates to the field of solid phase extraction, and in particular to a rapid separation device for solid phase extraction. Background Technology

[0002] Solid-phase extraction (SPE) is developed by combining liquid-solid extraction (LC) and liquid chromatography (LC). It is mainly used for the separation, purification and concentration of samples. Compared with traditional liquid-liquid extraction, it can improve the recovery rate of analytes, more effectively separate analytes from interfering components, reduce sample pretreatment, and is simple to operate, saving time and effort. It is widely used in pharmaceutical, food, environmental, commodity inspection and chemical industries.

[0003] Existing extraction devices mainly consist of an extraction column or similar component for adsorbing the target substance, a sample introduction device for transferring the liquid, a device for providing power or controlling the flow rate, and a collection device for collecting the eluent. Although the extraction devices currently used can separate the target substance from other impurities to improve the purity and concentration of the substance, the manual solid-phase extraction rapid separation device used in experiments requires the waste liquid generated during the process to be removed before the extraction step can be carried out. This is not only time-consuming but also reduces the extraction efficiency. Therefore, a solid-phase extraction rapid separation device is proposed to solve the above problems. Utility Model Content

[0004] To overcome the above shortcomings, this utility model provides a solid-phase extraction rapid separation device, which aims to improve the problem that the extraction column tray needs to be removed again after the waste liquid is extracted in the prior art, thus reducing the extraction efficiency.

[0005] To achieve the above objectives, the present invention adopts the following technical solution:

[0006] A solid-phase extraction rapid separation device includes a vacuum tank, a crossbar rotatably connected to the side of the vacuum tank, a knob fixedly connected to the side of the crossbar, a sealing gasket sleeved on the outer periphery of the crossbar, a retaining ring sleeved on the outside of the crossbar, a spring sleeved on the side of the retaining ring, a clamp fixedly connected to the left side of the crossbar, a flow guide plate installed on the side of the clamp, an extraction column tray installed on the top of the vacuum tank, a flow control valve fixedly connected to the top of the extraction column tray, a solid-phase extraction column installed on the top of the flow control valve, and a vacuum assembly installed on the side of the vacuum tank.

[0007] As a further description of the above technical solution:

[0008] A secondary rod is fixedly connected to the bottom of the extraction column tray. A spring is fixedly connected inside the secondary rod. A button is fixedly connected to the side of the spring. A main rod is slidably connected to the outer periphery of the secondary rod. A hole is opened on the side of the main rod.

[0009] As a further description of the above technical solution:

[0010] The vacuum chamber is equipped with a waste liquid box, the top of the waste liquid box is equipped with a test tube rack, and the middle of the test tube rack is equipped with a support leg.

[0011] As a further description of the above technical solution:

[0012] The vacuum assembly includes a connecting pipe, which is fixedly connected to the outside of the vacuum tank, and a vacuum pressure gauge is fixedly connected to the middle of the connecting pipe.

[0013] As a further description of the above technical solution:

[0014] The waste liquid box is internally threaded with a pull rod, and a pull rod head is fixedly connected to the top of the pull rod;

[0015] As a further description of the above technical solution:

[0016] The waste liquid box has a slot at the top, a baffle is installed at the top of the slot, and a guide channel is formed inside the baffle.

[0017] As a further description of the above technical solution:

[0018] The vacuum chamber is fixedly connected to a bracket inside;

[0019] As a further description of the above technical solution:

[0020] The waste liquid box has a waste liquid inlet at the top.

[0021] This utility model has the following beneficial effects:

[0022] 1. In this utility model, the rotation of the knob drives the crossbar, the crossbar drives the clamp, and thus drives the guide plate. When the knob is rotated, the guide plate will flip down and slide down through the guide groove. When it reaches a certain height, the guide plate will be supported by the bracket, thus solving the problem that the extraction column tray does not need to be removed every time the waste liquid is extracted.

[0023] 2. In this utility model, by pressing the button, the button drives the spring plate, and the auxiliary rod will slide down. When it reaches the next hole on the main rod, the button will be locked in the next hole. When you want to raise it, press the button, the button drives the spring plate, and the main rod will be pulled down. When it reaches the previous hole on the main rod, the button will be locked in the previous hole, thus achieving the telescopic effect. This avoids the problem of the guide needles contacting the ground when installing and using guide needles of different lengths. Attached Figure Description

[0024] Figure 1This is a three-dimensional schematic diagram of a solid-phase extraction rapid separation device proposed in this utility model;

[0025] Figure 2 This is a schematic cross-sectional view of the vacuum tank of a solid-phase extraction rapid separation device proposed in this utility model.

[0026] Figure 3 This is a schematic diagram of the structure of the guide plate of a solid-phase extraction rapid separation device proposed in this utility model;

[0027] Figure 4 This is a schematic diagram of the structure of a baffle in a solid-phase extraction rapid separation device proposed in this utility model;

[0028] Figure 5 This is a cross-sectional schematic diagram of the auxiliary rod of a solid-phase extraction rapid separation device proposed in this utility model;

[0029] Figure 6 This is a schematic diagram of the structure of a bracket for a rapid solid-phase extraction separation device proposed in this utility model;

[0030] Figure 7 This is a schematic diagram of the waste liquid box of a solid-phase extraction rapid separation device proposed in this utility model.

[0031] Legend:

[0032] 1. Solid-phase extraction column; 2. Flow control valve; 3. Extraction column tray; 4. Secondary rod; 5. Main rod; 6. Hole; 7. Vacuum chamber; 8. Connecting pipe; 9. Vacuum pressure gauge; 10. Knob; 11. Pull rod; 12. Bracket; 13. Crossbar; 14. Support leg; 15. Waste liquid box; 16. Waste liquid inlet; 17. Sealing gasket; 18. Spring; 19. Clip; 20. Drain plate; 21. Pull rod head; 22. Groove; 23. Baffle; 24. Guide groove; 25. Button; 26. Spring; 27. Test tube rack; 28. Retaining ring. Detailed Implementation

[0033] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0034] Reference Figure 1 and Figure 3This utility model provides an embodiment of a solid-phase extraction rapid separation device, including a vacuum tank 7. A crossbar 13 is rotatably connected to the side of the vacuum tank 7, and a knob 10 is fixedly connected to the side of the crossbar 13. A sealing gasket 17 is fitted around the outer periphery of the crossbar 13 to isolate external air and prevent air from entering the vacuum tank 7. A retaining ring 28 is fitted around the outside of the crossbar 13, and a spring 18 is fitted around the side of the retaining ring 28. A clamp 19 is fixedly connected to the left side of the crossbar 13, and a flow guide plate 20 is installed on the side of the clamp 19. By pulling the knob 10 outward, the spring 18 will be subjected to the retaining ring. The resistance at 28 retracts, allowing the lever head 21 to be pulled out, thus removing the waste liquid box 15. Rotating the knob 10 drives the crossbar 13, which in turn drives the clamp 19, thereby driving the guide plate 20. Rotating the knob 10 causes the guide plate 20 to flip downwards. The guide plate 20 is controlled by the clamp 13. An extraction column tray 3 is installed on the top of the vacuum tank 7. A flow control valve 2 is fixedly connected to the top of the extraction column tray 3. A solid phase extraction column 1 is installed on the top of the flow control valve 2. The solid phase extraction column 1 is used to extract the substances to be separated, and the flow rate is controlled by the flow control valve 2.

[0035] Reference Figure 2 , Figure 4 , Figure 6 and Figure 7 The vacuum tank 7 contains a waste liquid box 15. A test tube rack 27 is mounted on top of the waste liquid box 15. A support leg 14 is mounted in the middle of the test tube rack 27 to fix the test tube rack 27. A pull rod 11 is threaded inside the waste liquid box 15. A pull rod head 21 is fixedly connected to the top of the pull rod 11. The waste liquid box 15 can be removed by pulling out the pull rod head 21. A slot 22 is opened on the top of the waste liquid box 15, and a baffle 23 is mounted on the top of the slot 22. The baffle 23 is fixed through the slot 22. The baffle 23 has a guide channel 24 inside. The baffle 23 supports the guide plate 20 and can also prevent the waste liquid generated during the experiment from splashing onto the test tube rack 27. The vacuum tank 7 is fixedly connected to the bracket 12. The top of the waste liquid box 15 has a waste liquid slot 16. The guide plate 20 is supported by the bracket 12. The waste liquid is collected through the waste liquid slot 16 and flows into the waste liquid box 15.

[0036] Reference Figure 2 and Figure 5A secondary rod 4 is fixedly connected to the bottom of the extraction column tray 3. A spring piece 26 is fixedly connected inside the secondary rod 4. A button 25 is fixedly connected to the side of the spring piece 26. A main rod 5 is slidably connected to the outer periphery of the secondary rod 4. A hole 6 is opened on the side of the main rod 5. By pressing the button 25, the button 25 drives the spring piece 26, and the secondary rod 4 will slide down. When it reaches the next hole 6 on the main rod 5, the button 25 will be locked in the next hole 6. A vacuum assembly is installed on the side of the vacuum tank 7. The vacuum assembly includes a connecting pipe 8. The connecting pipe 8 is fixedly connected to the outside of the vacuum tank 7 and is connected to an external vacuum pump. A vacuum pressure gauge 9 is fixedly connected to the middle of the connecting pipe 8 and is used to display the pressure inside the vacuum tank 7.

[0037] Working principle: First, place the substance to be separated into the solid-phase extraction column 1, then open the flow control valve 2. The extracted waste liquid will flow along the guide plate 20 into the waste liquid inlet 16. The bottom of the guide plate 20 is supported by a baffle 23, which also prevents the waste liquid from splashing onto the test tube rack 27. The extracted waste liquid will then flow into the waste liquid box 15. The extracted waste liquid does not need to be removed from the extraction tray column 3. At this point, simply turn the knob 10. The knob 10 drives the crossbar 13, which in turn drives the clamp 19, thereby driving the guide plate 20. The guide plate 20 will slide along the guide groove 24 on the baffle 23. When it reaches a certain height, the bracket 12 inside the vacuum tank 7 will fix the guide plate 20. This allows you to proceed directly to the next step without removing the extraction column tray 3. To save time and improve efficiency, when all extraction steps are completed, to remove the waste liquid box 15, first remove the extraction tray column 3, then pull the knob 10 outward. At this time, the spring 18 will be resisted by the retaining ring 28 and retract. Then, the pull rod head 21 can be pulled out, and the waste liquid box 15 can be removed. If you want to install a guide needle at the bottom of the flow control valve 2, and the guide needle is too long to be placed directly on the table, you can press the button 25 in the auxiliary rod 4. The button 25 will be pushed inward by the elasticity of the spring piece 26. Then, you can pull the main rod 5 down. When the button reaches the next hole 6 on the main rod 5, the button 25 will be locked, thus achieving the telescopic effect. This will avoid the problem of the guide needle contacting the table when installing and using guide needles of different lengths.

[0038] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A solid phase extraction rapid separation device comprising a vacuum slot (7), characterised in that: A crossbar (13) is rotatably connected to the side of the vacuum tank (7). A knob (10) is fixedly connected to the side of the crossbar (13). A sealing gasket (17) is fitted around the outer periphery of the crossbar (13). A retaining ring (28) is fitted around the outside of the crossbar (13). A spring (18) is fitted around the side of the retaining ring (28). A clamp (19) is fixedly connected to the left side of the crossbar (13). A flow guide plate (20) is installed on the side of the clamp (19). An extraction column tray (3) is installed on the top of the vacuum tank (7). A flow control valve (2) is fixedly connected to the top of the extraction column tray (3). A solid phase extraction column (1) is installed on the top of the flow control valve (2). A vacuum pumping assembly is installed on the side of the vacuum tank (7).

2. The solid-phase extraction rapid separation device according to claim 1, characterized in that: The bottom of the extraction column tray (3) is fixedly connected to a secondary rod (4), and a spring piece (26) is fixedly connected inside the secondary rod (4). A button (25) is fixedly connected to the side of the spring piece (26). A main rod (5) is slidably connected to the outer periphery of the secondary rod (4), and a hole (6) is opened on the side of the main rod (5).

3. The solid-phase extraction rapid separation device according to claim 1, characterized in that: The vacuum tank (7) is equipped with a waste liquid box (15), a test tube rack (27) is installed on the top of the waste liquid box (15), and a support leg (14) is installed in the middle of the test tube rack (27).

4. The solid-phase extraction rapid separation device according to claim 1, characterized in that: The vacuum assembly includes a connecting pipe (8), which is fixedly connected to the outside of the vacuum tank (7), and a vacuum pressure gauge (9) is fixedly connected to the middle of the connecting pipe (8).

5. A rapid solid-phase extraction separation device according to claim 3, characterized in that: The waste liquid box (15) is internally threaded with a pull rod (11), and a pull rod head (21) is fixedly connected to the top of the pull rod (11).

6. The solid-phase extraction rapid separation device according to claim 3, characterized in that: The waste liquid box (15) has a slot (22) on the top, and a baffle (23) is installed on the top of the slot (22). A guide channel (24) is provided inside the baffle (23).

7. The solid-phase extraction rapid separation device according to claim 1, characterized in that: The vacuum tank (7) is fixedly connected to a bracket (12).

8. A solid-phase extraction rapid separation device according to claim 3, characterized in that: The waste liquid box (15) has a waste liquid trough (16) on its top.

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