Neutron target structure and neutron target device for boron neutron capture therapy

Abstract

The present disclosure provides a neutron target structure and a neutron target device for boron neutron capture therapy, the neutron target structure comprising: a target disc provided with an inlet flow channel and an outlet flow channel; a target sheet provided with an inlet hole and an outlet hole; and a quick connector assembly comprising a first quick connector and a second quick connector connected by a plug connection, the quick connector assembly being used to connect the inlet hole and the inlet flow channel and to connect the outlet hole and the outlet flow channel, so that the target sheet is detachably connected with the target disc. The neutron target structure of the present disclosure, the quick connector assembly comprising a first quick connector and a second quick connector connected by a plug connection, the inlet flow channel and the outlet flow channel of the target disc being connected with the first quick connector, the inlet hole and the outlet hole of the target sheet being connected with the second quick connector, the target sheet being connected with the target disc through the two quick connector assemblies, which is conducive to the convenience of installation and disassembly, and further conducive to the convenience of replacement.

Description

Technical Field

[0001] This disclosure relates to the field of neutron therapy equipment technology, and in particular to a neutron target structure and neutron target device for boron neutron capture therapy. Background Technology

[0002] Boron neutron capture therapy (BNCT) is a binary tumor treatment method that combines a thermal neutron beam with a tumor-loving boron-doped drug. It is a treatment for glioblastoma multiforme, malignant melanoma, and recurrent head and neck tumors, showing effective results for invasive, diffuse, nodular, or metastatic tumors. BNCT utilizes the capture reaction between boron atoms and thermal neutrons to release alpha ions and lithium ions with a range approximately equal to the radius of the cancer cells, destroying the genetic material of the cancer cells and thus achieving a therapeutic effect on the tumor.

[0003] The target plate is the component in a BNCT device that receives proton beams to generate neutrons. During treatment, the target layer on the target plate is gradually consumed, requiring periodic replacement to ensure treatment effectiveness. In related technologies, the target plate is often fixed to the target plate by screws, which is inconvenient for assembly and replacement. Utility Model Content

[0004] In view of this, embodiments of the present disclosure provide a neutron target structure and neutron target device for boron neutron capture therapy, which solves the problem of inconvenient target assembly and replacement in existing neutron target therapy equipment.

[0005] In a first aspect, embodiments of this disclosure provide a neutron target structure for boron neutron capture therapy, comprising:

[0006] The target plate is equipped with an inlet channel and an outlet channel;

[0007] The target plate is equipped with an inlet and an outlet; and

[0008] A quick-connector assembly includes a first quick-connector and a second quick-connector for plug-in connection. The quick-connector assembly is used to connect the liquid inlet and the liquid inlet channel, and to connect the liquid outlet and the liquid outlet channel, so that the target plate and the target disk can be detachably connected.

[0009] According to an embodiment of this disclosure, a first connecting hole and a second connecting hole are provided on the circumferential surface of the target disk, the first connecting hole communicating with the liquid inlet channel and the second connecting hole communicating with the liquid outlet channel;

[0010] The first quick-connector is connected to the first connecting hole and the second connecting hole, and the second quick-connector is connected to the liquid inlet hole and the liquid outlet hole.

[0011] According to an embodiment of this disclosure, the target plate is provided with a first fastening hole, and the target disk is provided with a second fastening hole;

[0012] The neutron target structure also includes fasteners that pass through the first fastening hole and the second fastening hole to fasten the target piece and the target disk.

[0013] According to embodiments of this disclosure, a plurality of inlet channels and a plurality of outlet channels are staggered along the circumferential direction of the target disk, the extension direction of the inlet channels is consistent with the radial direction of the target disk, and the extension direction of the outlet channels is consistent with the radial direction of the target disk.

[0014] Multiple target plates are arranged sequentially along the circumferential direction of the target disk, and the liquid inlet and liquid outlet of any target plate are respectively connected to the adjacent liquid inlet channel and liquid outlet channel.

[0015] According to embodiments of this disclosure, the target sheet includes:

[0016] A substrate having microchannels internally, with the liquid inlet and liquid outlet located at one end of the substrate; and

[0017] A target layer is disposed on one side of the substrate.

[0018] According to embodiments of this disclosure, the substrate includes:

[0019] A base, open on one side, has a receiving groove containing multiple partitions that form the microchannel; and

[0020] A sealing plate is used to seal the opening so that a sealed space is formed inside the substrate.

[0021] According to an embodiment of this disclosure, one end of the partition is connected to the bottom surface of the receiving groove, and the other end is connected to the sealing plate.

[0022] According to an embodiment of this disclosure, the circumferential surface of the target disk is planar, one end face of the base is planar, and the end face of the base is fitted to the circumferential surface of the target disk.

[0023] According to embodiments of this disclosure, the target layer includes a lithium layer or a beryllium layer.

[0024] Secondly, embodiments of this disclosure provide a neutron target device for boron neutron capture therapy, comprising:

[0025] A container having a receiving cavity;

[0026] The neutron target structure described above is disposed within the accommodating cavity; and

[0027] A rotating component is connected to the target disk of the neutron target structure and is used to drive the neutron target structure to rotate;

[0028] The rotating component is provided with an inlet chamber and an outlet chamber arranged coaxially. The inlet chamber is connected to the inlet channel, and the outlet chamber is connected to the outlet channel.

[0029] The neutron target structure and neutron target device for boron neutron capture therapy provided in the embodiments of this disclosure can achieve at least the following technical effects: the quick-connect assembly includes a first quick-connect connector and a second quick-connect connector that are connected by a plug-in connection. The first quick-connect connector is connected to the liquid inlet channel and the liquid outlet channel of the target disk, and the second quick-connect connector is connected to the liquid inlet hole and the liquid outlet hole of the target piece. The target piece is connected to the target disk through the two quick-connect connector assemblies, which facilitates the convenience of installation and disassembly, and thus facilitates the convenience of replacement. Attached Figure Description

[0030] The above and other objects, features and advantages of this disclosure will become clearer from the following description of embodiments with reference to the accompanying drawings, in which:

[0031] Figure 1 The schematic diagram illustrates one of the structural schematic diagrams of a neutron target structure according to an embodiment of the present disclosure;

[0032] Figure 2 The diagram illustrates a second structural schematic of a neutron target structure according to an embodiment of the present disclosure;

[0033] Figure 3A The schematic diagram illustrates one of the structural schematic diagrams of a target disk according to an embodiment of the present disclosure;

[0034] Figure 3B A second schematic diagram of the target disk structure according to an embodiment of the present disclosure is shown;

[0035] Figure 3C A schematic diagram of the target disk structure according to an embodiment of the present disclosure is shown in Figure 3.

[0036] Figure 3D A perspective view of a target disk according to an embodiment of the present disclosure is shown schematically;

[0037] Figure 3E A schematic cross-sectional view of a target disk according to an embodiment of the present disclosure is shown;

[0038] Figure 4A A schematic diagram of the structure of a target sheet according to an embodiment of the present disclosure is shown.

[0039] Figure 4B An explosion diagram of a target sheet according to an embodiment of the present disclosure is shown schematically;

[0040] Figure 4C One of the schematic diagrams of the internal structure of the substrate of the target chip according to an embodiment of the present disclosure is shown.

[0041] Figure 4D A schematic diagram of the internal structure of the substrate of the target chip according to an embodiment of the present disclosure is shown in the second example.

[0042] Figure 4E The diagram illustrates, for the third one, the internal structure of the substrate of the target chip according to an embodiment of the present disclosure;

[0043] Figure 5A A schematic diagram of the structure of a quick-connect assembly according to an embodiment of the present disclosure is shown.

[0044] Figure 5B An exploded view of a quick-connect assembly according to an embodiment of the present disclosure is shown schematically.

[0045] Figure 6 A schematic cross-sectional view of a neutron target device according to an embodiment of the present disclosure is shown.

[0046] Figure 7 A schematic diagram of the structure of a neutron target device according to an embodiment of the present disclosure is shown.

[0047] Figure 8 The schematic diagram illustrates the structure of the rotating component and the neutron target structure according to an embodiment of the present disclosure;

[0048] Figure 9 A schematic diagram of the structure of a rotating component according to an embodiment of the present disclosure is shown.

[0049] Figure 10 A schematic diagram of the structure of a first rotating body according to an embodiment of the present disclosure is shown.

[0050] Figure label:

[0051] 10: Container; 100: Receptacle; 20: Neutron target structure; 21: Target disk; 211: Liquid inlet channel; 212: Liquid outlet channel; 213: First surface; 214: Second surface; 215: Circumferential surface; 216: First connecting hole; 217: Second connecting hole; 218: Second fastening hole; 22: Target plate; 221: Substrate; 2211: Base; 2212: Sealing plate; 2213: Microchannel; 2214: Spare part Plate; 2215: Receiving tank; 222: Target layer; 223: Liquid inlet hole; 224: Liquid outlet hole; 225: First fastening hole; 23: Quick connector assembly; 231: First quick connector; 232: Second quick connector; 30: Rotating component; 31: First rotating body; 311: Through hole; 312: Through opening; 32: Second rotating body; 33: First sealing plate; 34: Second sealing plate; 310: Liquid outlet chamber; 320: Liquid inlet chamber. Detailed Implementation

[0052] To make the objectives, technical solutions, and advantages of this disclosure clearer, the following detailed description is provided in conjunction with specific embodiments and accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this disclosure. All other embodiments obtained by those skilled in the art based on the embodiments of this disclosure without inventive effort are within the scope of protection of this disclosure.

[0053] The terminology used herein is for the purpose of describing particular embodiments only and is not intended to limit this disclosure. The terms “comprising,” “including,” etc., as used herein indicate the presence of the stated features, steps, operations, and / or components, but do not exclude the presence or addition of one or more other features, steps, operations, or components.

[0054] In the description of this disclosure, it should be noted that, unless otherwise expressly specified and limited, the terms "installation," "connection," and "linkage" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection between two components. Those skilled in the art can understand the specific meaning of the above terms in this disclosure based on the specific circumstances.

[0055] Boron neutron capture therapy (BNCT) is a binary tumor treatment method that combines a thermal neutron beam with a tumor-loving boron-doped drug. It is a treatment for glioblastoma multiforme, malignant melanoma, and recurrent head and neck tumors, showing effective results for invasive, diffuse, nodular, or metastatic tumors. BNCT utilizes the capture reaction between boron atoms and thermal neutrons to release alpha ions and lithium ions with a range approximately equal to the radius of the cancer cells, destroying the genetic material of the cancer cells and thus achieving a therapeutic effect on the tumor.

[0056] Neutron targets for boron neutron capture therapy include lithium targets and beryllium targets. For boron neutron capture therapy devices with proton energies below 3 MeV, lithium targets are typically used. Lithium has a very low melting point of only 180.5 °C, making solid lithium targets prone to melting under heat. Effective cooling methods or rotating targets are required to prevent lithium evaporation. Meanwhile, liquid lithium targets have been proposed, but liquid lithium target technology is complex, difficult to implement, and costly.

[0057] In related technologies, target plates are cooled by rotating them and introducing coolant. During treatment, the target layer on the plate is gradually worn away, requiring periodic replacement to ensure treatment effectiveness. In these technologies, the target plate is often fixed to the target plate with screws, making assembly and replacement inconvenient.

[0058] The following is combined Figure 1 Figures 5 to 5 illustrate an embodiment of the present disclosure of a neutron target structure 20 for boron neutron capture therapy.

[0059] like Figure 1 As shown in Figure 5, the neutron target structure 20 provided in the embodiments of this disclosure includes a target disk 21, a target plate 22, and a quick-connect assembly 23. The target disk 21 is provided with a liquid inlet channel 211 and a liquid outlet channel 212. The target plate 22 is provided with a liquid inlet hole 223 and a liquid outlet hole 224. The quick-connect assembly 23 includes a first quick-connect connector 231 and a second quick-connect connector 232 for plug-in connection. The quick-connect assembly 23 is used to connect the liquid inlet hole 223 and the liquid inlet channel 211 and to connect the liquid outlet hole 224 and the liquid outlet channel 212, so that the target plate 22 is detachably connected to the target disk 21.

[0060] like Figures 3A to 3E As shown, the target disk 21 can be disc-shaped, approximately disc-shaped, square-shaped, etc., and the thickness of the target disk 21 is set according to actual needs. Figure 4A As shown, the target 22 includes a substrate 221 and a target layer 222 disposed on the substrate 221. The substrate 221 can be a copper substrate, an aluminum substrate, etc., and the target layer 222 can be a lithium layer, a beryllium layer, etc.

[0061] In some embodiments, such as Figure 3D and Figure 3E As shown, the target disk 21 is provided with an inlet channel 211 and an outlet channel 212. The extension direction of the inlet channel 211 can be consistent with the radial direction of the target disk 21, and the inlet channel 211 can extend to the circumferential surface 215 of the target disk 21. The extension direction of the outlet channel 212 can be consistent with the radial direction of the target disk 21, and the outlet channel 212 can extend to the circumferential surface 215 of the target disk 21. The cross-sectional areas of the inlet channel 211 and the outlet channel 212 are set according to actual needs. The cross-section of the inlet channel 211 can be circular, nearly circular, elliptical, square, polygonal, etc. The cross-section of the outlet channel 212 can be circular, nearly circular, elliptical, square, polygonal, etc.

[0062] In some embodiments, such as Figures 4A to 4E As shown, the target plate 22 can be approximately fan-shaped. The target plate 22 is provided with an inlet hole 223 and an outlet hole 224. It can be understood that the target plate 22 has a coolant chamber for coolant flow. Coolant flows into the target plate 22 through the inlet hole 223, flows within the coolant chamber to carry away heat from the target plate 22, and the cooled coolant, after absorbing heat, flows out through the outlet hole 224 and into the outlet channel 212 of the target plate 21. The size of the inlet hole 223 is adapted to the size of the inlet channel 211, and the size of the outlet hole 224 is adapted to the size of the outlet channel 212.

[0063] like Figure 5A and Figure 5B As shown, the quick-connect assembly 23 includes a first quick-connect connector 231 and a second quick-connect connector 232, which are capable of being plugged into each other. It can be understood that one of the first quick-connect connector 231 and the second quick-connect connector 232 is a male connector and the other is a female connector.

[0064] In some embodiments, the insertion direction of the quick-connect assembly 23 is aligned with the thickness direction of the target disk 21 and the target piece 22. Two first quick-connect connectors 231 are inserted at intervals along the thickness direction of the target disk 21 on one side of the target disk 21, with one first quick-connect connector 231 communicating with the liquid inlet channel 211 and the other first quick-connect connector 231 communicating with the liquid outlet channel 212. One surface of the target piece 22 is in contact with one surface of the target disk 21, and the target piece 22 is located at the edge of the target disk 21. One second quick-connect connector 232 is inserted into the liquid inlet hole 223, and the other second quick-connect connector 232 is inserted into the liquid outlet hole 224.

[0065] During the assembly of the target piece 22, the two second quick-connect connectors 232 and the two first quick-connect connectors 231 are aligned one by one. External force is applied to the target piece 22, causing the two second quick-connect connectors 232 to respectively connect to the two first quick-connect connectors 231, thus connecting the target piece 22 and the target disk 21. When the target piece 22 needs to be replaced, external force is applied to the target piece 22, causing the two second quick-connect connectors 232 to separate from the two first quick-connect connectors 231, allowing the target piece 22 to be removed.

[0066] In some embodiments, such as Figure 2 As shown, the insertion direction of the quick-connect assembly 23 is consistent with or nearly consistent with the radial direction of the target disk 21. Two first quick-connect connectors 231 are spaced apart along the circumferential direction of the target disk 21 at the circumferential surface 215 of the target disk 21, with one first quick-connect connector 231 communicating with the liquid inlet channel 211 and the other first quick-connect connector 231 communicating with the liquid outlet channel 212. One end face of the target piece 22 is in contact with the circumferential surface 215 of the target disk 21, and the liquid inlet hole 223 and the liquid outlet hole 224 are located at one end face of the target piece 22. One second quick-connect connector 232 is connected to the liquid inlet hole 223, and the other second quick-connect connector 232 is connected to the liquid outlet hole 224.

[0067] During the assembly of target 22, such as Figure 2 and Figure 4A As shown, the two second quick-connect connectors 232 and the two first quick-connect connectors 231 are aligned one by one, and a pushing force is applied to the target piece 22, so that the two second quick-connect connectors 232 are respectively inserted into the two first quick-connect connectors 231, thereby connecting the target piece 22 and the target plate 21. When it is necessary to replace the target piece 22, a pulling force is applied to the target piece 22, so that the two second quick-connect connectors 232 are separated from the two first quick-connect connectors 231, and the target piece 22 can be removed.

[0068] Two first quick-connect connectors 231 are respectively connected to the liquid inlet channel 211 and the liquid outlet channel 212 of the target plate 21, and two second quick-connect connectors 232 are respectively connected to the liquid inlet hole 223 and the liquid outlet hole 224 of the target piece 22. During the assembly of the target piece 22, the two second quick-connect connectors 232 are inserted into the two first quick-connect connectors 231 to connect the target piece 22 to the target plate 21. During the disassembly of the target piece 22, external force is applied to the target piece 22, causing the two second quick-connect connectors 232 to separate from the two first quick-connect connectors 231, thus allowing the target piece 22 to be removed. The connection between the target piece 22 and the target plate 21 via the quick-connect connector assembly 23 facilitates assembly and disassembly, and consequently, facilitates replacement.

[0069] In the embodiments of this disclosure, the quick-connect assembly 23 includes a first quick-connect connector 231 and a second quick-connect connector 232 that are plugged in. The first quick-connect connector 231 is connected to the liquid inlet channel 211 and the liquid outlet channel 212 of the target plate 21, and the second quick-connect connector 232 is connected to the liquid inlet hole 223 and the liquid outlet hole 224 of the target piece 22. The target piece 22 is connected to the target plate 21 through the two quick-connect assemblies 23, which facilitates the convenience of installation and disassembly, and thus facilitates the convenience of replacement.

[0070] like Figure 3A , Figure 3B , Figure 3C , Figure 3D and Figure 3E As shown, in an optional embodiment, a first connecting hole 216 and a second connecting hole 217 are provided on the circumferential surface 215 of the target disk 21. The first connecting hole 216 communicates with the liquid inlet channel 211, and the second connecting hole 217 communicates with the liquid outlet channel 212. A first quick-connect connector 231 is connected to the first connecting hole 216 and the second connecting hole 217, and a second quick-connect connector 232 is connected to the liquid inlet hole 223 and the liquid outlet hole 224.

[0071] The flow path of the liquid inlet channel 211 can be straight, wavy, or curved. The flow path of the liquid outlet channel 212 can be straight, wavy, or curved.

[0072] The liquid inlet channel 211 extends to near the circumferential surface 215 of the target disk 21. A first connecting hole 216 is provided at the circumferential surface 215 of the target disk 21. The first connecting hole 216 can be formed by casting or machining. The first connecting hole 216 communicates with the liquid inlet channel 211. It is understood that the first connecting hole 216 is adapted to the first quick connector 231, and the first quick connector 231 can be screwed into the first connecting hole 216. The end face of the first quick connector 231 can be flush with the circumferential surface 215 of the target disk 21.

[0073] The liquid outlet channel 212 extends to near the circumferential surface 215 of the target disk 21. A second connecting hole 217 is provided at the circumferential surface 215 of the target disk 21. The second connecting hole 217 can be formed by casting or machining. The second connecting hole 217 communicates with the liquid outlet channel 212. It is understood that the second connecting hole 217 is adapted to the first quick-connect connector 231, and the first quick-connect connector 231 can be screwed into the second connecting hole 217.

[0074] In some embodiments, the first connecting hole 216 and the second connecting hole 217 can be spaced apart along the circumferential direction of the target plate 21, which is beneficial for making the target plate 21 thinner. The corresponding liquid inlet hole 223 and liquid outlet hole 224 can be spaced apart along the arc length direction of the target plate 22.

[0075] In some embodiments, the first connecting hole 216 and the second connecting hole 217 may be spaced apart along the thickness direction of the target disk 21. The corresponding liquid inlet hole 223 and liquid outlet hole 224 may be spaced apart along the thickness direction of the target plate 22.

[0076] A liquid inlet hole 223 and a liquid outlet hole 224 are machined at one end face of the target plate 22. The liquid inlet hole 223 and the liquid outlet hole 224 communicate with the coolant chamber inside the target plate 22. The liquid inlet hole 223 and the liquid outlet hole 224 are adapted to a second quick connector 232, which can be screwed onto the liquid inlet hole 223 and the liquid outlet hole 224. The insertion part of the second quick connector 232 can be inserted into the insertion slot of the first quick connector 231.

[0077] The axial directions of the liquid inlet channel 211, quick-connect fitting assembly 23 and liquid inlet hole 223 are nearly aligned, which allows the coolant in the liquid inlet channel 211 to flow to the target plate 22 along the shortest path. The coolant can flow quickly from the target plate 21 into the target plate 22, which also helps to reduce the pressure drop on the flow system.

[0078] The axial directions of the liquid outlet 224, quick-connect fitting assembly 23 and liquid outlet channel 212 are nearly aligned, which allows the coolant with a higher temperature in the target plate 22 to flow to the target plate 21 along the shortest path. The coolant can flow quickly from the target plate 22 into the target plate 21, which also helps to reduce the pressure drop in the flow system.

[0079] Furthermore, machining the first connecting hole 216 and the second connecting hole 217 on the circumferential surface 215 of the target plate 21 facilitates machining. Machining the liquid inlet hole 223 and the liquid outlet hole 224 on the end face of the target plate 22 also facilitates machining.

[0080] After the target plate 22 and target disk 21 are assembled, the coolant in the inlet channel 211 flows into the target plate 22 through the quick-connect fitting assembly 23, and the coolant in the target plate 22 flows into the outlet channel 212 through the quick-connect fitting assembly 23. During the process of coolant flowing from the target disk 21 to the target plate 22 and from the target plate 22 to the target disk 21, the quick-connect fitting assembly 23 can ensure the sealing of the connection between the target disk 21 and the target plate 22, preventing coolant from leaking out from the connection between the target plate 22 and the target disk 21.

[0081] During the installation and removal of the target piece 22, the target piece 22 can be installed or removed by applying a pushing force to the target piece 22 in the direction opposite to the target plate 21 or by applying a pulling force to the target piece 22 in the direction opposite to the target plate 21, which is conducive to the convenience of operation.

[0082] In the embodiments disclosed herein, a first connecting hole 216 and a second connecting hole 217 are provided on the circumferential surface 215 of the target plate 21. The first connecting hole 216 communicates with the liquid inlet channel 211, and the second connecting hole 217 communicates with the liquid outlet channel 212. A first quick-connect connector 231 is connected to the first connecting hole 216 and the second connecting hole 217. This flow path structure makes the axial directions of the liquid inlet channel 211, the quick-connect connector assembly 23, and the liquid inlet hole 223 nearly aligned, allowing the coolant to flow quickly from the target plate 21 into the target plate 22. The axial directions of the liquid outlet hole 224, the quick-connect connector assembly 23, and the liquid outlet channel 212 are nearly aligned, allowing the coolant to flow quickly from the target plate 22 into the target plate 21. This not only improves the cooling rate of the target plate 22 but also facilitates processing, installation, and disassembly.

[0083] like Figure 3A , Figure 3B , Figure 3C , Figure 4C , Figure 4D and Figure 4E As shown, in an optional embodiment, the target plate 22 is provided with a first fastening hole 225, and the target disk 21 is provided with a second fastening hole 218. The neutron target structure 20 also includes fasteners that pass through the first fastening hole 225 and the second fastening hole 218 to fasten the target plate 22 and the target disk 21.

[0084] For the neutron target structure 20 that needs to be rotated, the target disk 21 and the target plate 22 need to rotate during the treatment process. In order to prevent the target plate 22 from detaching from the target disk 21 due to centrifugal force caused by high-speed rotation, the target plate 22 is connected to the target disk 21 by fasteners.

[0085] In some embodiments, a second fastening hole 218 is provided on the circumferential surface 215 of the target disk 21. The second fastening hole 218 can be a threaded hole. A first fastening hole 225 is provided at one end of the target piece 22 near the target disk 21. The first fastening hole 225 can be a through hole or a threaded hole. The through hole can be a countersunk hole. The number of first fastening holes 225 and second fastening holes 218 is set according to actual needs. For example, four first fastening holes 225 are spaced apart on the circumference of the liquid inlet hole 223 and the liquid outlet hole 224, and four second fastening holes 218 are spaced apart on the circumference of the first connecting hole 216 and the second connecting hole 217.

[0086] Fasteners include screws. During the installation of the target piece 22, the two second quick-connect connectors 232 are first inserted into the two first quick-connect connectors 231. At this time, the circumferential surface 215 of the target plate 21 is in contact with the end face of the target piece 22. Then, the screws are screwed into the first fastening hole 225 and the second fastening hole 218 to achieve a tight connection between the target piece 22 and the target plate 21, ensuring the firmness of the connection.

[0087] If it is necessary to disassemble the target piece 22, first remove the screws, and then apply an outward pulling force to the target piece 22 to separate the target piece 22 from the target plate 21.

[0088] In the embodiments disclosed herein, the target plate 22 is provided with a first fastening hole 225, and the target plate 21 is provided with a second fastening hole 218. Fasteners pass through the first fastening hole 225 and the second fastening hole 218 to achieve a tight connection between the target plate 22 and the target plate 21, which can ensure the firmness of the connection and facilitate installation and disassembly.

[0089] like Figure 3D and Figure 3E As shown, in an optional embodiment, multiple inlet channels 211 and multiple outlet channels 212 are staggered along the circumferential direction of the target disk 21. The extending direction of the inlet channels 211 is consistent with the radial direction of the target disk 21, and the extending direction of the outlet channels 212 is consistent with the radial direction of the target disk 21. Multiple target pieces 22 are arranged sequentially along the circumferential direction of the target disk 21, and the inlet hole 223 and outlet hole 224 of any target piece 22 are connected to the adjacent inlet channel 211 and outlet channel 212, respectively.

[0090] Multiple target pieces 22 are spaced apart along the circumferential direction of the target disk 21. The number of target pieces 22 is set according to actual needs, and there can be two or more target pieces 22. For example, there are 16 target pieces 22, which are spaced apart along the circumferential direction of the target disk 21.

[0091] Each target plate 22 corresponds to one inlet channel 211 and one outlet channel 212 on the target plate 21. When there are multiple target plates 22, the multiple inlet channels 211 and multiple outlet channels 212 are staggered along the circumferential direction of the target plate 21, with the inlet channels 211 and outlet channels 212 forming a certain angle. The extension direction of the inlet channel 211 is consistent with or nearly consistent with the radial direction of the target plate 21, minimizing the coolant flow path and reducing the coolant flow time within the target plate 21, thus accelerating the coolant flow towards the target plate 22. The extension direction of the outlet channel 212 is consistent with or nearly consistent with the radial direction of the target plate 21, minimizing the coolant flow path and reducing the coolant flow time within the target plate 21, thus accelerating the discharge of the hotter coolant.

[0092] In the embodiments of this disclosure, the extension direction of the inlet channel 211 and the extension direction of the outlet channel 212 are nearly consistent with the radial direction of the target plate 21, which is beneficial to shorten the flow time of the coolant in the target plate 21. In addition, it is beneficial to set more inlet channels 211 and outlet channels 212 on the target plate 21, and each target plate 22 has an independent inlet channel 211 and outlet channel 212, which is beneficial to accelerate the flow of coolant into the target plate 22 and the flow of coolant out of the target plate 22, thereby further improving the cooling rate of each target plate 22.

[0093] like Figure 3E As shown, in an optional embodiment, at least a portion of the inlet channel 211 and at least a portion of the outlet channel 212 are offset along the thickness direction of the target disk 21.

[0094] The extending directions of the inlet channel 211 and the outlet channel 212 are approximately aligned with the radial direction of the target disk 21. Near the center of the target disk 21, due to limited space, certain sections of the inlet channel 211 and the outlet channel 212 are offset along the thickness direction of the target disk 21. For example, a section of the inlet channel 211 is closer to the first surface 213 of the target disk 21, and a section of the outlet channel 212 is closer to the second surface 214 of the target disk 21.

[0095] In the embodiments of this disclosure, when the size of the target disk 21 is fixed, the inlet channel 211 and the outlet channel 212 are partially staggered, which can avoid interference between the two in the central area near the target disk 21. In addition, it is beneficial to set a larger number of inlet channels 211 and outlet channels 212 in the limited space on the target disk 21, making the flow path structure more compact.

[0096] like Figure 4A , Figure 4B , Figure 4C , Figure 4D and Figure 4E As shown, in an optional embodiment, the target 22 includes a substrate 221 and a target layer 222. The substrate 221 has microchannels 2213 internally constructed, and one end of the substrate 221 is provided with a liquid inlet 223 and a liquid outlet 224. The target layer 222 is disposed on one side of the substrate 221.

[0097] A coolant chamber is formed inside the substrate 221, and a microchannel 2213 is constructed inside the coolant chamber. The microchannel 2213 can be processed inside the substrate 221 by machining. The microchannel 2213 helps to prolong the flow time of the coolant in the substrate 221, increase the contact area between the coolant and the substrate 221, and thus help to improve the cooling rate of the target 22.

[0098] In some embodiments, the main body of the substrate 221 is fan-shaped, and one end of the substrate 221 has a liquid inlet hole 223 and a liquid outlet hole 224. The liquid inlet hole 223 and the liquid outlet hole 224 are located at the inner arc of the substrate 221 and are spaced apart along the arc length direction. Both the liquid inlet hole 223 and the liquid outlet hole 224 are connected to the microchannel 2213. Coolant flows into the coolant chamber through the liquid inlet hole 223, flows through the microchannel 2213, and flows out through the liquid outlet hole 224.

[0099] The target layer 222 includes a lithium layer, a beryllium layer, etc. The target layer 222 can be formed on a surface of the substrate 221 by chemical deposition, lamination, or other methods.

[0100] In the embodiments of this disclosure, a microchannel 2213 is constructed in the substrate 221. The coolant flows into the coolant chamber through the inlet hole 223. During the process of flowing through the microchannel 2213, it can fully contact the substrate 221. The heat transferred from the target layer 222 to the substrate 221 can be effectively transferred to the coolant, which is beneficial to improving the cooling rate of the target 22.

[0101] like Figure 4B , Figure 4C , Figure 4D and Figure 4E As shown, in an optional embodiment, the substrate 221 includes a base 2211 and a sealing plate 2212. One side of the base 2211 is open, and the base 2211 has a receiving groove 2215. A plurality of partitions 2214 are disposed within the receiving groove 2215, forming microchannels 2213. The sealing plate 2212 seals the openness, thereby forming a sealed space inside the substrate 221.

[0102] The substrate 221 consists of two parts: a base 2211 and a sealing plate 2212, to facilitate the fabrication of the microchannel 2213. The base 2211 includes an integrally formed first part and a second part. The first part is approximately square-shaped, and its thickness is adapted to the thickness of the target disk 21 to allow for the machining of an inlet hole 223, an outlet hole 224, and a first fastening hole 225. The second part is fan-shaped, and a receiving groove 2215 and multiple partitions 2214 located within the receiving groove 2215 can be machined onto the second part, thus making the second part open. Multiple partitions 2214 are arranged in an array to form the microchannel 2213. The extension direction of some partitions 2214 is approximately aligned with the axial direction of the inlet hole 223, and the extension direction of some partitions 2214 is approximately aligned with the axial direction of the outlet hole 224. The number of partitions 2214 is determined according to actual requirements.

[0103] The receiving tank 2215 has opposing first and second tank walls. The first tank wall is close to the inlet hole 223 and the outlet hole 224, while the second tank wall is away from the inlet hole 223 and the outlet hole 224. It is understood that one end of the partition 2214 has a first gap with the first tank wall, and the other end of the partition 2214 has a second gap with the second tank wall. The first and second gaps are set according to actual needs to ensure that the coolant can flow sufficiently within the base plate 221.

[0104] The sealing plate 2212 can be connected to the second part of the base 2211 by welding to seal the opening, so that a sealed space is formed inside the base plate 221, ensuring the sealing performance of the connection between the sealing plate 2212 and the base 2211.

[0105] In the embodiments of this disclosure, the substrate 221 is composed of a base 2211 and a sealing plate 2212. Microchannels 2213 formed by multiple partitions 2214 are processed on the base 2211, and then the sealing plate 2212 and the base 2211 are connected, which facilitates the manufacturing process.

[0106] In an optional embodiment, one end of the partition 2214 is connected to the bottom surface of the receiving groove 2215, and the other end is connected to the sealing plate 2212.

[0107] In some embodiments, the sealing plate 2212 has a groove on the side facing the base 2211, and multiple grooves are arranged in an array. Each groove corresponds to a multiple partition plate 2214, and each groove is filled with solder, including welding rods. After the sealing plate 2212 and the base 2211 containing the solder are assembled, they are placed in a furnace for high-temperature melting and welding, thereby connecting one end of the partition plate 2214 to the wall of the receiving groove 2215 and the other end to the sealing plate 2212. Afterwards, the sealing plate 2212 and the base 2211 are removed, and the sealing plate 2212 is welded to the base 2211 along the circumference of the sealing plate 2212.

[0108] If the partition 2214 is only connected to the base 2211, and the coolant flows within the substrate 221, the substrate 221 will bulge under the long-term impact of the coolant. This will cause the coolant flowing into the target 22 and the coolant flowing out of the target 22 to interfere with each other, affecting the cooling effect. In addition, it will damage the target layer 222, affecting the treatment effect.

[0109] In the embodiments of this disclosure, one end of the partition 2214 is connected to the bottom surface of the receiving groove 2215, and the other end is connected to the sealing plate 2212. Multiple connection points are formed between the sealing plate 2212 and the base 2211, which can effectively prevent the substrate 221 from bulging and prevent the coolant from flowing turbulently in the substrate 221, ensuring cooling efficiency. In addition, it can prevent damage to the target layer 222 and improve the service life of the target sheet 22.

[0110] like Figure 3A , Figure 3B , Figure 3C , Figure 3D and Figure 4D As shown, in an optional embodiment, the circumferential surface 215 of the target disk 21 is planar, one end face of the base 2211 is planar, and the end face of the base 2211 is fitted to the circumferential surface 215 of the target disk 21.

[0111] The circumferential surface 215 of the target disk 21 is planar, meaning that the circumferential surface 215 of the target disk 21 is formed by connecting multiple planes in sequence. Machining the first connecting hole 216, the second connecting hole 217, and the second fastening hole 218 on the plane facilitates machining.

[0112] One end of the base 2211 can be formed into a square-shaped connecting part, and an inlet hole 223, an outlet hole 224 and a first fastening hole 225 are machined on the connecting part, which is beneficial to the convenience of processing.

[0113] The end face of the base 2211 and the circumferential surface 215 of the target disk 21 are in contact. After the fastener connects the target piece 22 and the target disk 21, the end face of the target piece 22 and the circumferential surface 215 of the target disk 21 are in close contact, which prevents the coolant from leaking out from the connection between the target piece 22 and the target disk 21, and helps to further improve the sealing of the connection between the target piece 22 and the target disk 21.

[0114] In the embodiments of this disclosure, one end face of the base 2211 is planar, and the circumferential surface 215 of the target disk 21 is planar. The end face of the base 2211 and the circumferential surface 215 of the target disk 21 are fitted together, which is beneficial to the convenience of preparation and also to further improve the sealing of the connection between the target piece 22 and the target disk 21.

[0115] like Figure 6 , Figure 7 and Figure 8 As shown, embodiments of this disclosure also provide a neutron target device for boron neutron capture therapy. The neutron target device includes a container 10, a neutron target structure 20, and a rotating component 30. The container 10 has a receiving cavity 100, in which the neutron target structure 20 is disposed. The rotating component 30 is connected to the target disk 21 of the neutron target structure 20 and is used to drive the neutron target structure 20 to rotate. The rotating component 30 has a coaxially arranged inlet cavity 320 and an outlet cavity 310. The inlet cavity 320 communicates with an inlet flow channel 211, and the outlet cavity 310 communicates with an outlet flow channel 212.

[0116] The neutron target structure 20 is as described above and will not be elaborated upon here.

[0117] Container 10 is used to house the neutron target structure 20. The shape of container 10 can be circular, approximately circular, square, etc. Container 10 can be approximately flat. Container 10 has a receiving cavity 100 that can accommodate the neutron target structure 20. A vacuum pump can be used to evacuate the receiving cavity 100, so that a vacuum chamber is formed inside container 10.

[0118] It is understandable that, such as Figure 6 and Figure 7 As shown, the neutron target device also includes a proton beam channel, one end of which is connected to the container 10 and the other end to the proton accelerator. The proton beam emitted by the proton accelerator hits the target plate 22 through the proton beam channel, generating neutrons. The neutrons are then shaped by a beam shaper into a neutron beam that can be used for tumor treatment. The neutron beam is further directed to the patient's treatment area for treatment.

[0119] In some embodiments, the container 10 includes a container body and a lid. One end of the container body is open, forming an installation space for mounting the neutron target component. The lid covers the open end of the container body, and the lid and the container body can be connected by screwing, snap-fitting, welding, or other methods. It is understood that the container body has a through hole, the diameter of which is adapted to the outer diameter of the rotating component 30. During the installation of the neutron target component and the rotating component 30, the rotating component 30 can pass through the through hole of the container body, and the neutron target component is located in the receiving cavity 100 of the container 10.

[0120] like Figure 6 As shown, the rotating component 30 has two opposing ends, defined as a first end and a second end. The first end is connected to a cooling component, and the second end is connected to a target plate 21. The cooling component supplies coolant. The rotating component 30 has a coaxially arranged inlet chamber 320 and outlet chamber 310. The inlet chamber 320 can extend from the first end to the second end, and the outlet chamber 310 can extend from the first end to the second end. Optionally, the inlet chamber 320 and outlet chamber 310 are arranged sequentially from the outside to the inside along the radial direction of the rotating component 30. Optionally, the inlet chamber 320 and outlet chamber 310 are arranged sequentially from the inside to the outside along the radial direction of the rotating component 30.

[0121] like Figure 6 and Figure 9 As shown, in an optional embodiment, the rotating component 30 includes a first rotating body 31 and a second rotating body 32. The first rotating body 31 is connected to the target disk 21 and has a liquid outlet cavity 310. The first rotating body 31 has a through hole 311, and the liquid outlet cavity 310 communicates with the liquid outlet channel 212 through the through hole 311. The second rotating body 32 is coaxially arranged with the first rotating body 31 and connected to the target disk 21. A liquid inlet cavity 320 is formed between the outer wall surface of the first rotating body 31 and the inner wall surface of the second rotating body 32.

[0122] The first rotating body 31, the second rotating body 32, and the target disk 21 can be coaxially arranged. Both the first rotating body 31 and the second rotating body 32 can be hollow cylindrical bodies. The lengths of the first rotating body 31 and the second rotating body 32 are set according to actual needs, and the lengths of the first rotating body 31 and the second rotating body 32 are the same or nearly the same. Both the first rotating body 31 and the second rotating body 32 are connected to the target disk 21.

[0123] The first rotating body 31 is provided with a liquid outlet cavity 310, which extends through both opposite ends of the first rotating body 31, that is, the liquid outlet cavity 310 extends from the first end to the second end of the first rotating body 31 along the axial direction of the first rotating body 31. The first rotating body 31 and the target disk 21 can be connected by welding. The liquid outlet cavity 310 can be formed by casting or machining.

[0124] In some embodiments, a through hole is provided at the center of the target disk 21, the diameter of the through hole is adapted to the outer diameter of the first rotating body 31, the second end of the first rotating body 31 is embedded in the through hole, and the second end face of the first rotating body 31 can be flush with the second surface 214 of the target disk 21. The first rotating body 31 and the target disk 21 are connected by welding.

[0125] like Figure 10 As shown, the second end of the first rotating body 31 is provided with a through hole 311, the position of which corresponds to the target disk 21, and the through hole 311 penetrates the inner wall surface and the outer wall surface of the first rotating body 31. One end of the liquid outlet channel 212 extends to communicate with the through hole 311, and the other end of the liquid outlet channel 212 can extend to communicate with the circumferential surface 215 of the target disk 21.

[0126] In some embodiments, the liquid outlet cavity 310 can be gradually shaped, meaning that the radial dimension of the liquid outlet cavity 310 increases as it approaches the target disk 21. Near the second end of the first rotating body 31, the radial dimension of the liquid outlet cavity 310 increases, allowing for more through holes 311 to be provided at the second end. When there are multiple liquid outlet channels 212, each channel corresponds to one through hole 311. This one-to-one communication between the multiple liquid outlet channels 212 and the multiple through holes 311 facilitates faster coolant discharge. When there are multiple through holes 311, they are spaced apart and circumferentially arranged at the second end of the first rotating body 31.

[0127] like Figure 6As shown, the rotating component 30 also includes a first sealing plate 33, which is in contact with the second surface 214 of the target disk 21 and corresponds to the through hole of the target disk 21. The first sealing plate 33 can be connected to the target disk 21 by welding or screwing. The first sealing plate 33 is used to prevent the coolant in the liquid outlet chamber 310 from flowing into the receiving cavity 100 of the container 10. When the first sealing plate 33 and the first rotating body 31 are connected to the target disk 21 by welding, there is no need to install a sealing ring at the connection. The welding method can ensure the sealing of the connection and prevent the coolant from flowing into the container 10.

[0128] The second rotating body 32 can be a hollow columnar body. It is understood that the inner diameter of the second rotating body 32 is larger than the outer diameter of the first rotating body 31.

[0129] In some embodiments, the second rotating body 32 can be connected to the target disk 21 by welding. For example, the second end face of the second rotating body 32 is attached to the first surface 213 of the target disk 21, and welding is performed around the second end of the second rotating body 32 to achieve the connection between the second rotating body 32 and the target disk 21.

[0130] In some embodiments, the second rotating body 32 can be connected to the target disk 21 via a plug-in connection. For example, the target disk 21 has a first positioning hole, and the second rotating body 32 has a second positioning hole. The first positioning hole and the second positioning hole are correspondingly arranged, and the number of the first positioning hole and the second positioning hole is set according to actual needs. During the assembly of the second rotating body 32 and the target disk 21, a positioning pin is inserted into the first positioning hole, and then the second positioning hole is aligned with the positioning pin. The positioning pin is then inserted into the second positioning hole of the second rotating body 32, thereby connecting the second rotating body 32 and the target disk 21.

[0131] After the first rotating body 31 and the second rotating body 32 are connected to the target disk 21, the outer wall surface of the first rotating body 31 and the inner wall surface of the second rotating body 32 enclose each other to form a liquid inlet cavity 320. Along the axial direction of the rotating component 30, the cross-section of the liquid inlet cavity 320 can be a constant cross-section or a variable cross-section.

[0132] The liquid inlet channel 211 includes a first section and a second section that are connected. The extension direction of the first section is approximately the same as the radial direction of the target disk 21, and the first section extends to the wall surface of the through hole of the target disk 21. The extension direction of the second section is the same as the axial direction of the target disk 21. One end of the second section is connected to the first section, and the other end of the second section extends to be connected to the first surface 213 of the target disk 21. The second section corresponds to and is connected to the liquid inlet chamber 320.

[0133] The first rotating body 31 is provided with a liquid outlet chamber 310 and a through hole 311. The liquid outlet channel 212 is connected to the liquid outlet chamber 310 through the through hole 311, and multiple liquid outlet channels 212 are connected to the liquid outlet chamber 310 through multiple through holes 311. This flow path structure is beneficial for setting multiple liquid outlet channels on the target plate 21 and the first rotating body 31, which is beneficial for accelerating the discharge of coolant.

[0134] After the first rotating body 31 and the second rotating body 32 are connected to the target plate 21, the outer wall surface of the first rotating body 31 and the inner wall surface of the second rotating body 32 naturally form a liquid inlet cavity 320. The liquid inlet cavity 320 is annular, and multiple liquid inlet channels 211 can be connected to the liquid inlet cavity 320. This flow path structure is beneficial for setting multiple liquid inlet channels on the target plate 21, which is conducive to accelerating the inflow of coolant.

[0135] The first rotating body 31 is provided with a liquid outlet cavity 310 and a through hole 311. The outer wall surface of the first rotating body 31 and the inner wall surface of the second rotating body 32 enclose the liquid inlet cavity 320. The liquid outlet cavity 310 can be connected to multiple liquid outlet channels 212 through multiple through holes 311. The liquid inlet cavity 320 can be connected to multiple liquid inlet channels 211. This is beneficial to set multiple liquid inlet and liquid outlet channels on the rotating component 30 and the target plate 21, which is beneficial to further accelerate the inflow and outflow of coolant, and thus improve the cooling rate of the target plate 22.

[0136] The cooling component is connected to the first end of the rotating component 30. The cooling component may include a liquid supply line communicating with the liquid inlet chamber 320 for supplying coolant. The coolant enters the liquid inlet chamber 320 along the liquid supply line, flows along the liquid inlet chamber 320, flows into the liquid inlet channel 211 of the target plate 21, and under the action of centrifugal force, flows along the liquid inlet channel 211 into the liquid inlet hole 223 of the target plate 22. The coolant flows within the target plate 22, carrying away the heat from the target plate 22. Then, the coolant flows along the liquid outlet hole 224 of the target plate 22 into the liquid outlet channel 212 of the target plate 21, further flowing into the liquid outlet chamber 310 and being discharged from the end of the liquid outlet chamber 310. The cooling component may also include a drain line communicating with the liquid outlet chamber 310. The drain line may be connected to a collection tank, allowing the higher-temperature coolant discharged from the drain line to be cooled in the collection tank and then recycled. The coolant may be water, oil, ethylene glycol, liquid nitrogen, etc.

[0137] In some embodiments, the rotating component 30 further includes a second sealing plate 34, which is annular. A stop portion is formed at the first end of the first rotating body 31, and the second sealing plate 34 is sleeved on the stop portion. The outer wall surface of the second sealing plate 34 is in contact with the inner wall surface of the second rotating body 32. The second sealing plate 34 can be connected to the second rotating body 32 by welding. The second sealing plate 34 ensures the sealing at the first end of the rotating component 30.

[0138] The cooling component has a liquid supply chamber and a liquid discharge chamber. The liquid supply chamber is connected to the liquid inlet chamber 320, and the liquid discharge chamber is connected to the liquid outlet chamber 310. The first end of the first rotating body 31 is also provided with a through-port 312, which penetrates both the inner and outer walls of the first rotating body 31. The liquid supply chamber is connected to the liquid inlet chamber 320 through the through-port 312. The number of through-ports 312 is set according to actual needs; for example, four through-ports 312 are circumferentially spaced at the first end of the first rotating body 31. The cooling component also includes a liquid supply pipe and a liquid pump. The liquid supply pipe is connected to the liquid supply port, and the liquid pump is located on the liquid supply pipe to pump coolant into the rotating component 30.

[0139] The rotating component 30 is provided with an inlet chamber 320 and an outlet chamber 310, the target plate 21 is provided with an inlet channel 211 and an outlet channel 212, and the target plate 22 is provided with an inlet hole 223 and an outlet hole 224. The extension direction of the inlet chamber 320 is consistent with or nearly consistent with the axial direction of the rotating component 30, eliminating the need for a liquid supply pipe in the radial direction of the rotating component 30, which is beneficial for miniaturization of the radial dimensions of the rotating component 30. The inlet chamber 320 is annular, giving it a large cross-sectional area, which helps to increase the flow velocity of the coolant within the inlet chamber 320. The extension direction of the inlet channel 211 can be consistent with or nearly consistent with the radial direction of the target plate 21. The coolant flows along the inlet chamber 320, into the inlet channel 211, and further into the target plate 22. The arrangement of the inlet channel 211 increases the flow velocity of the coolant within the target plate 21, allowing the coolant to flow quickly into the target plate 22.

[0140] The extension direction of the outlet channel 212 is consistent with or nearly consistent with the radial direction of the target plate 21. The coolant in the target plate 22 carries away the heat of the target plate 22, increasing the temperature of the coolant. It then flows to the outlet hole 224 of the target plate 22 and further flows into the outlet channel 212 from the outlet hole 224. The arrangement of the outlet channel 212 increases the flow velocity of the coolant in the target plate 21, allowing the hotter coolant to flow quickly into the outlet chamber 310. The extension direction of the outlet chamber 310 is consistent with the axial direction of the rotating component 30, eliminating the need for a drain pipe in the radial direction of the rotating component 30, which is beneficial for miniaturization of the radial dimension of the rotating component 30.

[0141] The extension direction of the inlet chamber 320 is consistent with the axial direction of the rotating component 30, and the extension direction of the inlet channel 211 is consistent with the radial direction of the target plate 21, thereby increasing the flow velocity of the coolant into the target plate 22. The extension direction of the outlet chamber 310 is consistent with the axial direction of the rotating component 30, and the extension direction of the outlet channel 212 is consistent with the radial direction of the target plate 21, thereby increasing the flow velocity of the coolant discharged from the target plate 22. The inlet chamber 320, the inlet channel 211, the outlet channel 212, and the outlet chamber 310 constitute the flow path of the coolant in the rotating component 30 and the target plate 21. This flow path structure effectively increases the flow velocity of the coolant in the rotating component 30 and the target plate 21, thereby improving the cooling rate of the target plate 22. In addition, this flow path structure contributes to the compactness of the overall structure.

[0142] In the embodiments of this disclosure, the rotating component 30 is connected to the target disk 21. The rotating component 30 is provided with a coaxially arranged liquid inlet chamber 320 and liquid outlet chamber 310. The target disk 21 is provided with a liquid inlet channel 211 and a liquid outlet channel 212. The liquid inlet chamber 320, the liquid inlet channel 211 and the liquid inlet hole 223 are interconnected. The liquid outlet chamber 310, the liquid outlet channel 212 and the liquid outlet hole 224 are interconnected. This flow path structure is beneficial to increasing the flow velocity of the coolant in the rotating component 30 and the target disk 21, thereby improving the cooling rate of the target plate 22. In addition, this flow path structure is beneficial to the compactness of the overall structure of the neutron target device. Furthermore, the target plate 22 is connected to the target disk 21 through the quick-connect connector assembly 23, which is beneficial to the convenience of installation and disassembly, and thus to the convenience of replacement.

[0143] The above description is merely a specific embodiment of this disclosure, but the scope of protection of this application is not limited thereto. Any changes or substitutions made within the spirit and principles of this disclosure should be covered within the scope of protection of this application. Therefore, the scope of protection of this application should be determined by the scope of the claims.

Claims

1. A neutron target structure for boron neutron capture therapy, characterized in that, include: The target plate is equipped with an inlet channel and an outlet channel; The target plate is equipped with a liquid inlet and a liquid outlet. as well as A quick-connector assembly includes a first quick-connector and a second quick-connector for plug-in connection. The quick-connector assembly is used to connect the liquid inlet and the liquid inlet channel, and to connect the liquid outlet and the liquid outlet channel, so that the target plate and the target disk can be detachably connected.

2. The neutron target structure according to claim 1, characterized in that, The target disk has a first connecting hole and a second connecting hole on its circumferential surface. The first connecting hole is connected to the liquid inlet channel, and the second connecting hole is connected to the liquid outlet channel. The first quick-connector is connected to the first connecting hole and the second connecting hole, and the second quick-connector is connected to the liquid inlet hole and the liquid outlet hole.

3. The neutron target structure according to claim 1, characterized in that, The target plate is provided with a first fastening hole, and the target disk is provided with a second fastening hole; The neutron target structure also includes fasteners that pass through the first fastening hole and the second fastening hole to fasten the target piece and the target disk.

4. The neutron target structure according to claim 1, characterized in that, The plurality of liquid inlet channels and the plurality of liquid outlet channels are staggered along the circumferential direction of the target disk, the extension direction of the liquid inlet channels is consistent with the radial direction of the target disk, and the extension direction of the liquid outlet channels is consistent with the radial direction of the target disk. Multiple target plates are arranged sequentially along the circumferential direction of the target disk, and the liquid inlet and liquid outlet of any target plate are respectively connected to the adjacent liquid inlet channel and liquid outlet channel.

5. The neutron target structure according to any one of claims 1 to 4, characterized in that, The target plate includes: A substrate having microchannels internally, with the liquid inlet and liquid outlet located at one end of the substrate; and A target layer is disposed on one side of the substrate.

6. The neutron target structure according to claim 5, characterized in that, The substrate includes: A base, open on one side, has a receiving groove containing multiple partitions that form the microchannel; and A sealing plate is used to seal the opening so that a sealed space is formed inside the substrate.

7. The neutron target structure according to claim 6, characterized in that, One end of the partition is connected to the bottom surface of the receiving groove, and the other end is connected to the sealing plate.

8. The neutron target structure according to claim 6, characterized in that, The circumferential surface of the target disk is planar, and one end face of the base is planar. The end face of the base is fitted to the circumferential surface of the target disk.

9. The neutron target structure according to claim 5, characterized in that, The target layer includes a lithium layer or a beryllium layer.

10. A neutron target device for boron neutron capture therapy, characterized in that, include: A container having a receiving cavity; The neutron target structure as described in any one of claims 1 to 9, wherein the neutron target structure is disposed in the accommodating cavity; and A rotating component is connected to the target disk of the neutron target structure and is used to drive the neutron target structure to rotate; The rotating component is provided with an inlet chamber and an outlet chamber arranged coaxially. The inlet chamber is connected to the inlet channel, and the outlet chamber is connected to the outlet channel.

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