An integrated glue tray and a matching glue making device

Abstract

The utility model discloses an integral type glue dish, including the glue dish body that is provided with the top opening, the glue dish body both sides still symmetrically seted up first side opening and second side opening, the inside setting of glue dish body has the partition of U type, and the top height of both ends of partition is different and forms the identification part, and the glue dish body of both sides of partition is separated and forms first glue groove and second glue groove. Integral type glue dish adopts the special structure design, can be taken out independently, and is put into the test tube of most different kinds size currently, does not need to cut the gel, and the target DNA molecule is obtained quickly through the heating melting gel, and the gel is effectively avoided to be contaminated. In addition, the matched gel preparation device adopts the design of multiple gel preparation grooves, can make the glue dish in batches, and the specification is unified, and the operation is convenient.

Description

Technical Field

[0001] This utility model relates to the field of gel electrophoresis technology, specifically to an integrated gel dish and a matching gel preparation device. Background Technology

[0002] Currently, there are various methods for extracting and purifying genomic nucleic acids (DNA and RNA), which can be mainly divided into three categories from a technical principle perspective: 1. Chemical reagent extraction methods (such as phenol-chloroform extraction, SDS method, etc.); 2. Physical adsorption methods (such as centrifuge columns or filtration membranes, and magnetic bead adsorption); 3. Chromatographic filtration methods (such as high performance liquid chromatography, gel chromatography columns, etc.). Each method has its advantages and disadvantages. Chemical reagent methods are low-cost, but involve multiple steps and require the use of centrifuges; physical adsorption methods have high consumable costs and require specialized equipment and instruments (such as centrifuges, extractors, etc.); chromatographic filtration methods have costs between the two, but also require specialized laboratory equipment such as gel chromatography instruments.

[0003] Gel electrophoresis is an essential diagnostic technique in modern molecular biology experiments and has been widely and successfully applied worldwide for decades. Various biomolecules are separated due to their different migration velocities under the combined effects of an electric field and gel molecular sieves, making it a simple and effective method for separation and identification.

[0004] Gel dishes are essential equipment in gel electrophoresis. However, existing gel dishes are relatively large, requiring cutting the gel after electrophoresis for collection, which is a complex operation and poses a risk of contamination. Furthermore, the existing structure makes it difficult to control deformation stress during gel preparation, leading to unevenness on the gel surface both inside and outside the dish, and even gel detachment from the inside of the dish. Summary of the Invention

[0005] The purpose of this invention is to solve the problems in the prior art and provide an integrated glue container and matching glue-making device that is easy to manufacture, small in size, and can be inserted whole into a test tube.

[0006] To achieve the above objectives, the technical solution of this utility model is as follows:

[0007] An integrated glue container includes a glue container body with a top opening, and a first side opening and a second side opening symmetrically opened on both sides of the glue container body. The glue container body has a U-shaped partition inside, and the tops of the two ends of the partition are at different heights to form an identification part. The glue container body on both sides of the partition is divided to form a first glue groove and a second glue groove.

[0008] Preferably, the corners of the outer surface of the glue dish body are rounded, and the corners of the inner wall of the glue dish body are also rounded.

[0009] Preferably, the separator is integrally formed with the glue dish body.

[0010] A glue-making device for use with an integrated glue container includes a glue-making base with multiple glue-making troughs arranged in parallel. The shape of the glue-making troughs matches the integrated glue container and is used to place the integrated glue container. A detachable comb is inserted into the glue-making base. The comb is provided with comb plates that correspond one-to-one with the glue-making troughs. The comb plates are inserted into the partition of the integrated glue container, and a gap is formed between the top of the comb plate and the bottom of the partition.

[0011] Preferably, the glue-making base has positioning grooves on both sides, and the comb has positioning posts on both sides that correspond to and are inserted into the positioning grooves.

[0012] Preferably, a connecting groove is provided on the top of the glue-making base between two adjacent glue-making tanks.

[0013] Preferably, the top of the glue-making base is provided with a cover plate, and the cover plate has a through hole for the comb to pass through.

[0014] Preferably, the area of ​​the cover plate is larger than the area of ​​the top of the glue-making base.

[0015] The beneficial effects of this utility model are:

[0016] 1. The integrated gel dish of this application adopts a special structural design that allows it to be removed independently and placed into most test tubes of different sizes. It does not require cutting the gel and can quickly obtain the target DNA molecule by heating and melting the gel, effectively avoiding gel contamination.

[0017] 2. The integrated gel dish adopts a wrap-around design, which makes it easy to seal the top opening of the gel dish with melted gel, effectively preventing sample contamination and improving the accuracy of experimental results.

[0018] 3. The matching glue-making device adopts a design with multiple glue-making tanks, which can produce glue containers in batches, and the specifications are uniform and the operation is convenient. Attached Figure Description

[0019] Figure 1 This is a schematic diagram of the integrated glue dish of this utility model;

[0020] Figure 2 This is a top-view structural diagram of the integrated adhesive dish of this utility model.

[0021] Figure 3 for Figure 2 Sectional view along the middle AA direction;

[0022] Figure 4 This is a schematic diagram of the adhesive making device of this utility model;

[0023] Figure 5 This is a top view of the structure of the glue-making device of this utility model;

[0024] Figure 6 for Figure 5 Sectional view along the BB direction;

[0025] Figure 7 This is a schematic diagram of the adhesive base in the adhesive making device of this utility model;

[0026] Figure 8 This is a schematic diagram of the comb in the glue-making device of this utility model. Detailed Implementation

[0027] To enable those skilled in the art to better understand the present invention, the invention will be further described in detail below with reference to the accompanying drawings and embodiments.

[0028] like Figures 1-3 The illustrated integrated gel container includes a container body 1 with a top opening 13. The container body 1 also has symmetrically arranged first side openings 11 and second side openings 12 on both sides. A U-shaped partition 2 is integrally formed with the container body 1. The tops of the partition 2 are at different heights, forming a high and low identification section 29. This design allows operators to easily distinguish the gel on the left and right sides. The corners of the outer surface of the container body 1 are rounded, making the outer surface smooth and less prone to collisions with other tools. The gel dish body 1 on both sides of the separator 2 is divided to form a first gel tank 21 and a second gel tank 22. The width of the first gel tank 21 is greater than the width of the first side opening 11, and the first gel tank 21 and the first side opening 11 form a first space for gel preparation. The width of the second gel tank 22 is greater than the width of the second side opening 12, and the second gel tank 22 and the second side opening 12 form a second space for gel preparation. Simultaneously, the corners of the inner wall of the gel dish body 1 are also rounded. This structure allows the prepared gel to be stably placed in the gel tank, preventing it from loosening, and also controls and improves the deformation stress during gel preparation. This ensures that the gel surface inside and outside the frame is flat during gel preparation and prevents the gel inside the frame from falling off, facilitating the subsequent handling of various chemical reagents. Furthermore, the integrated gel dish of this embodiment can be designed to be smaller in size, eliminating the need to break or cut the gel during subsequent experiments. The entire gel dish can be placed into a test tube, effectively avoiding gel contamination.

[0029] like Figures 4-8The illustrated adhesive-making apparatus for use with an integrated adhesive container includes an adhesive-making base 3 with multiple adhesive-making troughs 31 arranged in parallel. The shape of each adhesive-making trough 31 matches the integrated adhesive container and is used to place the container and perform adhesive-making. A detachable comb 4 is inserted into the adhesive-making base 3. Each comb 4 has a comb plate 41 corresponding to one of the adhesive-making troughs 31. The comb plate 41 is inserted into the partition portion 2 of the integrated adhesive container, with a gap 44 formed between the top of the comb plate 41 and the bottom of the partition portion 2. During adhesive-making, the integrated adhesive container is first placed into the corresponding adhesive-making trough 31, then adhesive-making raw materials are poured into each trough 31. Next, the comb 4 is inserted into the adhesive-making base 3, at which point each comb plate 41 is inserted into the partition portion 2 of each integrated adhesive container. After the gel-forming raw material in the gel tank 31 solidifies, the comb 4 is pulled out from the gel-forming base 3. At this time, gel sheets are formed in the first gel tank 21 and the second gel tank 22 of the integrated gel dish, and a groove for accommodating electrophoretic materials is formed in the center of the integrated gel dish.

[0030] As a preferred embodiment, the glue-making base 3 has positioning grooves 5 on both sides, and the comb 4 has positioning posts 51 on both sides that correspond to and are inserted into the positioning grooves 5. The design of the positioning posts 51 and positioning grooves 5 can fix the insertion position of the comb 4 and comb plate 41, so as to simultaneously batch-make glue for multiple integrated glue containers on the glue-making base 3, and the glue-making specifications are uniform with small errors. In addition, a connecting groove 33 is formed on the top of the glue-making base 3 between two adjacent glue-making tanks 31. This connecting groove 33 can balance the amount of glue-making raw material in each glue-making tank 31 during glue-making, so that the amount of glue-making raw material in each glue-making tank 31 is as consistent as possible.

[0031] As another preferred embodiment, the top of the gel-forming base 3 is provided with a cover plate 6, and the cover plate 6 has a through hole 61 for the comb 4 to pass through. The area of ​​the cover plate 6 is larger than the area of ​​the top of the gel-forming base 3. The cover plate 6 presses on the gel-forming base 3, which can keep the top of the produced gel sheet flat.

[0032] The above description is only a preferred embodiment of the present utility model, but the protection scope of the present utility model is not limited thereto. Any equivalent substitutions or changes made by those skilled in the art within the technical scope disclosed in the present utility model, based on the technical solution and the inventive concept of the present utility model, should be included within the protection scope of the present utility model.

Claims

1. A one-piece glue container, characterized in that: The device includes a glue dish body (1) with a top opening (13). The glue dish body (1) also has a first side opening (11) and a second side opening (12) symmetrically opened on both sides. The glue dish body (1) has a U-shaped partition (2) inside. The tops of the two ends of the partition (2) are at different heights to form identification parts (29). The glue dish body (1) on both sides of the partition (2) is divided to form a first glue groove (21) and a second glue groove (22).

2. The integrated glue container according to claim 1, characterized in that: The corners of the outer side of the glue dish body (1) are rounded, and the corners of the inner wall of the glue dish body (1) are also rounded.

3. The integrated glue container according to claim 2, characterized in that: The partition (2) and the glue dish body (1) are integrally formed.

4. A glue-making apparatus compatible with the integrated glue container as described in claim 1, characterized in that: The device includes a glue-making base (3) with multiple glue-making tanks (31) arranged in parallel. The shape of the glue-making tanks (31) matches that of the integrated glue dish and is used to place the integrated glue dish. A detachable comb (4) is inserted into the glue-making base (3). The comb (4) is provided with comb plates (41) that correspond one-to-one with the glue-making tanks (31). The comb plates (41) are inserted into the partition (2) of the integrated glue dish, and a gap (44) is formed between the top of the comb plate (41) and the bottom of the partition (2).

5. The glue-making apparatus for the integrated glue container according to claim 4, characterized in that: The glue base (3) has positioning grooves (5) on both sides, and the comb (4) has positioning posts (51) on both sides that correspond to and are inserted into the positioning grooves (5).

6. The glue-making apparatus for the integrated glue container according to claim 4, characterized in that: A connecting groove (33) is provided on the top of the glue-making base (3) between two adjacent glue-making tanks (31).

7. The glue-making apparatus for the integrated glue container according to claim 4, characterized in that: The glue-making base (3) is provided with a cover plate (6) on top, and the cover plate (6) has a through hole (61) for the comb (4) to pass through.

8. The glue-making apparatus for the integrated glue container according to claim 7, characterized in that: The area of ​​the cover plate (6) is larger than the area of ​​the top of the glue base (3).

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