Medical patch with medicine loading groove
By designing drug-carrying grooves and sustained-release skeleton structures on medical dressings, the problem of excessively rapid drug release in traditional dressings has been solved, achieving controllable sustained drug release and increased drug loading capacity, making it suitable for various wound treatments.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH
- Filing Date
- 2025-03-10
- Publication Date
- 2026-06-26
AI Technical Summary
Traditional medical dressings release drugs too quickly in hot environments, resulting in short-lasting effects and short dressing replacement cycles, which cannot meet the needs of special scenarios.
The medical dressing is designed with a drug-loaded reservoir. The reservoir contains a hydrogel layer filled with drug, which is combined with a sustained-release matrix fabricated by three-dimensional micro-nano printing. The drug is distributed on the sustained-release matrix, forming a drug-matrix loading structure.
It achieves controlled and sustained drug release, increases drug loading and patch utilization, extends application time, avoids secondary trauma caused by frequent dressing changes, and expands the scope of application.
Smart Images
Figure CN224403871U_ABST
Abstract
Description
Technical Field
[0001] This utility model belongs to the field of biomedical materials and wound care technology, and in particular relates to a medical dressing with a drug-carrying tank. Background Technology
[0002] The skin, the largest organ in the human body, performs various functions including barrier protection, absorption and metabolism, secretion and excretion, thermoregulation, and immunity. Medical dressings are products used for localized skin cooling, analgesia, physical therapy, and wound healing. They are applied to the skin surface to achieve therapeutic or adjunctive therapeutic effects. When healthy skin is injured, medical dressings cover the wound, protecting it from bacterial and microbial infection and preventing further damage. Some high-performance functional medical dressings also offer additional benefits such as accelerated antibacterial activity, hemostasis, faster wound healing, and reduced scarring.
[0003] Traditional medical dressings typically consist of a backing layer, a gel layer, and an anti-adhesive layer. In a heated environment, the drug release and evaporation are too rapid, resulting in short-lasting efficacy, short dressing change cycles, poor patient experience, and inability to meet the needs of some special scenarios, such as military scenarios.
[0004] To ensure that medication can be applied continuously and stably to the wound surface over a period of time, avoiding frequent dressing changes and achieving a steady and controllable release, modern medical dressings are gradually being developed into controlled-release drug delivery systems. This invention is based on this research. Utility Model Content
[0005] The purpose of this invention is to provide a medical dressing with a drug-carrying tank, which has a large drug-carrying capacity and can slow down the drug release rate.
[0006] To achieve the above objectives, this application adopts the following technical solution:
[0007] This utility model provides a medical dressing with a drug-carrying groove. The medical dressing includes a polyurethane film and an anti-adhesive layer. The polyurethane film has a plurality of drug-carrying grooves. A hydrogel layer is provided in the drug-carrying grooves. The hydrogel layer is filled with a drug. The anti-adhesive layer is in close contact with the side of the polyurethane film with the drug-carrying grooves.
[0008] In the above technical solution, the drug-carrying grooves are arranged in a matrix on the polyurethane film.
[0009] In the above technical solutions, the shape of the drug-carrying groove is one of square, trapezoidal, T-shaped, or arc-shaped.
[0010] In the above technical solution, the thickness of the polyurethane film is 0.012-0.035mm, and the depth of the drug-carrying groove is 5-20μm.
[0011] In the above technical solutions, a hydrogel layer is also provided on the polyurethane film where the drug-carrying groove is not provided.
[0012] In the above technical solutions, the thickness of the hydrogel layer on the polyurethane film where the drug-carrying groove is not provided is 10-50 μm.
[0013] In the above technical solution, the drug is distributed on the sustained-release matrix to form a drug-matrix loading structure, and the drug-matrix loading structure is filled in the hydrogel layer.
[0014] In the above technical solution, the sustained-release matrix is a three-dimensional micro-nano printed framework structure with a hollow inner cavity, and the drug is distributed in the inner cavity of the sustained-release matrix.
[0015] In the above technical solution, the shape of the sustained-release skeleton matches the shape of the drug-carrying groove, thereby maximizing the number of sustained-release skeletons in the drug-carrying groove.
[0016] The beneficial effects of this utility model are as follows:
[0017] 1. The medical dressing of this utility model has a drug-carrying groove in the polyurethane film, which can significantly increase the drug loading capacity of the medical dressing.
[0018] 2. The drug-carrying groove of the medical dressing of this utility model is filled with a hydrogel layer, and the drug is loaded in the hydrogel, which can improve the sustained release ability of the medical dressing.
[0019] 3. In this utility model, the drug in the medical dressing is distributed on the sustained-release matrix, which is prepared by three-dimensional micro-nano printing. The shape of the sustained-release matrix is customized according to the shape of the drug-carrying groove to maximize the number of sustained-release matrices in the drug-carrying groove. The inner cavity of the sustained-release matrix is hollow, and the drug is loaded on the sustained-release matrix, so that the drug-carrying groove can hold more drug and increase the drug loading capacity of the medical dressing.
[0020] 4. In this utility model of medical dressing, the drug is distributed on the sustained-release matrix, forming a drug-matrix loading structure, which can achieve a good sustained-release effect. It still has the ability to release drugs after 7 days of use, thereby greatly improving the utilization rate and durability of the medical dressing, avoiding secondary trauma during dressing changes, and facilitating wound repair.
[0021] 5. The medical dressing of this utility model has a drug-skeleton load structure, which can load more types of drugs and expand the application range of medical dressings.
[0022] 6. This utility model of medical dressing abandons drug carriers such as cotton fabric and gauze strips, and selects polyurethane film. The thickness of polyurethane film is 0.012-0.035mm, which has the characteristics of being thin, waterproof, breathable and preventing microbial invasion. Attached Figure Description
[0023] Figure 1 This invention provides a schematic diagram of the structure of a medical dressing with a drug-carrying groove on a polyurethane film.
[0024] Figure 2 A schematic diagram of the structure of Embodiment 1 of the medical dressing of this utility model is shown;
[0025] Figure 3 A schematic diagram of the structure of embodiment 2 of the medical dressing of this utility model is shown;
[0026] Figure 4 A schematic diagram of the structure of embodiment 3 of the medical dressing of this utility model is shown;
[0027] Figure 5 yes Figure 4 Enlarged view of A in the middle;
[0028] The components are: 1. polyurethane film; 2. drug-carrying tank; 3. anti-stick layer; 4. hydrogel layer; 5. drug; 6. sustained-release matrix; 7. drug-matrix loading structure. Detailed Implementation
[0029] To better illustrate the purpose, technical solution, and advantages of this utility model, it will be further described below with reference to specific embodiments. This utility model can be implemented in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the concept of this utility model to those skilled in the art, who will define this utility model only by the claims.
[0030] Unless otherwise specified, the test methods or experimental methods described in the following examples are conventional methods; unless otherwise specified, the reagents and materials are obtained from conventional commercial sources or prepared by conventional methods.
[0031] Unless otherwise specified, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains.
[0032] This utility model provides a medical dressing with drug-carrying slots. The medical dressing includes a polyurethane film 1 and an anti-adhesive layer 3. The polyurethane film 1 has a plurality of drug-carrying slots 2 arranged in a matrix on the polyurethane film 1. Figure 1 As shown.
[0033] The drug-carrying tank 2 is provided with a hydrogel layer 4, which is filled with drug 5. The anti-adhesive layer 3 is tightly attached to the side of the polyurethane film 1 where the drug-carrying tank 2 is located.
[0034] The shape of the drug-carrying tank 2 can be one of square, trapezoidal, T-shaped, or arc-shaped.
[0035] The thickness of the polyurethane film 1 is 0.012-0.035 mm, and the depth of the drug-carrying groove 2 is 5-20 μm.
[0036] In this invention, the drugs include those for treating wound infections, diabetic foot ulcers, and pressure ulcers. For example: hydrophilic drugs for treating wound infections include povidone-iodine, chlorhexidine, hydrogen peroxide solution, and various types of antibiotics. Hydrophilic drugs for treating diabetic foot ulcers include vitamin B12, various hydrophilic anti-infective drugs mentioned in the treatment of infected wounds, and Kangfuxin solution. Hydrophilic drugs for treating pressure ulcers include drugs with active ingredients such as hyaluronic acid, alginate, hydrogel, honey, aloe vera, and epidermal growth factor. Hydrophobic drugs for treating wound infections include erythromycin ointment, mupirocin ointment, metronidazole gel, neomycin B ointment, ciprofloxacin ointment, clindamycin phosphate gel, and silver sulfadiazine. Hydrophobic drugs for treating pressure ulcers include drugs with active ingredients such as collagen and silver ions.
[0037] Example 1
[0038] like Figure 2 As shown, the drug-carrying tank 2 is square in shape, with a depth of 20 μm and a length and width of 10 μm. The drug 5 is evenly distributed in the drug-carrying tank 2.
[0039] Example 2
[0040] like Figure 3 As shown, based on Example 1, a hydrogel layer 4 with a thickness of 30 μm is also provided on the polyurethane film 1 where there is no drug loading groove 2.
[0041] Example 3
[0042] like Figure 4-5 As shown, based on Example 1, the sustained-release matrix 6 is square in shape, and multiple sustained-release matrix 6 are distributed in a matrix within the drug loading groove 2, just filling the drug loading groove 2. The drug 5 is distributed within the cavity of the sustained-release matrix 6, forming a drug-matrix loading structure 7, which is filled in the hydrogel layer 4.
[0043] Obviously, the above embodiments are merely illustrative examples for clear explanation and are not intended to limit the implementation. Those skilled in the art will recognize that other variations or modifications can be made based on the above description. It is neither necessary nor possible to exhaustively list all possible implementations here. However, obvious variations or modifications derived therefrom are still within the protection scope of this invention.
Claims
1. A medical dressing with a drug-carrying tank, characterized in that: The medical dressing includes a polyurethane film and an anti-adhesive layer. The polyurethane film has a plurality of drug-carrying grooves, and a hydrogel layer is provided in the drug-carrying grooves. The hydrogel layer is filled with a drug, and the anti-adhesive layer is in close contact with the side of the polyurethane film with the drug-carrying grooves.
2. The medical dressing according to claim 1, characterized in that: The drug-loaded grooves are arranged in a matrix on the polyurethane film.
3. The medical dressing according to claim 1, characterized in that: The shape of the drug-carrying groove is one of square, trapezoidal, T-shaped, or arc-shaped.
4. The medical dressing according to claim 1, characterized in that: The thickness of the polyurethane film is 0.012-0.035 mm, and the depth of the drug-carrying groove is 5-20 μm.
5. The medical dressing according to claim 1, characterized in that: The polyurethane film also has a hydrogel layer in the areas where the drug-carrying groove is not provided.
6. The medical dressing according to claim 5, characterized in that: The thickness of the hydrogel layer on the polyurethane film where the drug-carrying groove is not provided is 10-50 μm.
7. The medical dressing according to claim 1, characterized in that: The drug is distributed on the sustained-release matrix to form a drug-matrix loading structure, which is filled in the hydrogel layer.
8. The medical dressing according to claim 7, characterized in that: The sustained-release matrix is a three-dimensional micro-nano printed framework structure with a hollow interior, in which the drug is distributed.
9. The medical dressing according to claim 7, characterized in that: The shape of the sustained-release skeleton matches the shape of the drug-carrying groove, thereby maximizing the number of sustained-release skeletons in the drug-carrying groove.