Sample loading components, sample loading devices and experimental equipment

Abstract

A sample loading assembly, a sample loading device, and an experimental apparatus are disclosed. The sample loading assembly includes a tube body, a plug, and a connector. The tube body has a hollow cavity and opposing first and second openings, both of which communicate with the cavity. The plug is located at one end of the tube body and is used to close the second opening, allowing the cavity to accommodate the sample to be transferred. The connector is located at the end of the tube body away from the plug and closes the first opening. The connector has a flow channel communicating with the cavity to allow fluid to flow into the cavity. When the air pressure inside the cavity exceeds a preset value, the plug separates from the tube body to release the second opening. This sample loading assembly simplifies the sample loading process, improves experimental efficiency and accuracy, and ensures experimental safety.

Description

Technical Field

[0001] This utility model relates to the field of experimental equipment technology, specifically to a sample addition component, a sample addition device, and experimental equipment. Background Technology

[0002] In biological, chemical, and other related experiments, solid samples are often required as reactants to participate in chemical reactions. Current methods for quantitatively adding solid samples involve manually weighing the sample using an analytical balance and then manually transferring it to the reaction vessel using weighing paper or a weighing boat.

[0003] The aforementioned manual sample addition method is time-consuming and labor-intensive, greatly increasing the workload of experimental personnel, resulting in low experimental efficiency and hindering automation integration. Moreover, manual addition is prone to introducing human error, affecting experimental accuracy. Furthermore, for experiments requiring the addition of solid samples during the reaction process, manual addition can easily cause injury to experimental personnel due to splashing of reaction liquid. Utility Model Content

[0004] The purpose of this invention is to provide a sample addition component, sample addition device, and experimental equipment that can simplify the sample addition process, improve experimental efficiency and accuracy, and ensure experimental safety.

[0005] To achieve the objectives of this utility model, the following technical solution is provided:

[0006] In a first aspect, this utility model provides a sample dispensing assembly, including a tube body, a plug, and a connector. The tube body has a hollow cavity and opposing first and second openings, both of which communicate with the cavity. The plug is disposed at one end of the tube body and is used to close the second opening, so that the cavity can accommodate the sample to be transferred. The connector is disposed at the end of the tube body away from the plug and is used to close the first opening. The connector has a flow channel that communicates with the cavity to allow fluid to flow into the cavity.

[0007] When the air pressure inside the cavity is greater than a preset value, the plug separates from the tube body to unseal the second opening.

[0008] In one embodiment, the tube body has an axis extending along a first direction, the first opening and the second opening are opposite to each other in the first direction, the connector has an axis extending along the first direction, and the axis of the connector is collinear with the axis of the tube body; the flow channel includes a first channel and a second channel, the first channel extends along the first direction, the second channel connects the first channel and the tube cavity, and the extension direction of the second channel has a first included angle α with the first direction, satisfying: 30°≤α≤150°.

[0009] In one embodiment, one end opening of the second channel is located on the side wall of the connector; the second channel extends radially along the connector, or extends tangentially along the radial section of the connector, or extends toward the second opening; the included angle α satisfies: 90°≤α≤150°.

[0010] In one embodiment, there are multiple second channels, and the openings of the multiple second channels on the sidewall of the connector are distributed at intervals along the circumference of the connector, and all of the multiple second channels are in communication with the first channel.

[0011] In one embodiment, the plug is slidably connected to the pipe body, and the outer peripheral surface of the plug is either interference-fitted or transition-fitted to the inner wall of the pipe cavity.

[0012] In one embodiment, the outer peripheral surface of the plug that contacts the lumen is a smooth, convex curved surface.

[0013] In one embodiment, the sample dispensing assembly further includes a connector located at one end of the tube body near the second opening and connecting the plug and the tube body; the plug is rotatably connected to the tube body, and the connector is used to allow the plug to rotate relative to the tube body.

[0014] In one embodiment, the plug is made of any one of polytetrafluoroethylene, ceramic, Hastelloy, or titanium alloy.

[0015] In one embodiment, the connector is detachably connected to the pipe body.

[0016] In one embodiment, the inner diameter of the tube remains constant or gradually decreases in the direction from the first opening to the second opening.

[0017] Secondly, the present invention also provides a sample dispensing device, including a sample dispensing actuator and a sample dispensing component as described in any of the various embodiments of the first aspect, wherein the sample dispensing actuator is used to connect to the sample dispensing component and to introduce fluid into the sample dispensing component.

[0018] In one embodiment, the connector is fixedly connected to the sample feeding mechanism, and the connector is detachably connected to the tube body.

[0019] In one embodiment, the sampling actuator includes a fluid chamber containing fluid; a connector connects the fluid chamber to the lumen to allow the fluid in the fluid chamber to flow into the lumen; the sampling actuator further includes a switching valve connecting the connector and the fluid chamber, the switching valve being used to control the connection or disconnection between the connector and the fluid chamber.

[0020] In one embodiment, the fluid chamber is fixedly connected to the connector and located at the end of the connector away from the plug; the fluid chamber contains a fixed amount of fluid, and the flow channel connects the fluid chamber and the lumen to allow the fixed amount of fluid in the fluid chamber to be introduced into the lumen.

[0021] In one embodiment, the sample addition device further includes a liquid addition mechanism, which is used to communicate with the connector and inject cleaning liquid or reaction liquid into the tube body through the connector.

[0022] In one embodiment, the connector further has a liquid filling channel, which connects the liquid filling mechanism and the cavity; the liquid filling channel includes a third channel and a fourth channel, the third channel is connected to the liquid filling mechanism, the fourth channel is connected to the third channel and the cavity, and one end opening of the fourth channel is located on the side wall of the connector.

[0023] In one embodiment, the sampling device further includes a liquid extraction mechanism, which is configured to communicate with the connector and create a negative pressure in the lumen to allow liquid to enter the lumen through the second opening, and create a positive pressure in the lumen to allow liquid in the lumen to exit through the second opening.

[0024] Thirdly, the present invention also provides an experimental apparatus, including a sample loading component as described in any one of the various embodiments of the first aspect, or including a sample loading device as described in any one of the various embodiments of the second aspect.

[0025] In one embodiment, the experimental equipment further includes a transport device connected to the sample application assembly or the sample application device, and used to move the components thereon.

[0026] By configuring a tube body, a plug, and a connector, the plug is placed at one end of the tube body and seals the second opening of the tube body. When it is necessary to unseal the second opening, fluid is introduced into the tube cavity through the connector located at the first opening, so that the air pressure in the tube cavity is greater than a preset value, thereby separating the plug from the tube body and allowing the sample to be transferred in the tube cavity to be ejected. No manual sample addition is required, which simplifies the sample addition process and improves experimental efficiency. At the same time, under the action of air pressure, the sample in the tube body will be ejected quickly, reducing sample residue and improving experimental accuracy. In addition, since no human intervention is required, experimental safety is improved and it is conducive to automation integration. Attached Figure Description

[0027] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0028] Figure 1 A perspective view of a sample dispensing device according to one embodiment;

[0029] Figure 2 This is a partial cross-sectional front view of a sample dispensing device according to one embodiment;

[0030] Figure 3 yes Figure 2 A magnified view of a section at point A in the middle;

[0031] Figure 4 This is a schematic diagram of the radial cross-section of a connector according to one embodiment.

[0032] Explanation of reference numerals in the attached figures:

[0033] 100 - Sample dispensing device;

[0034] 10-Sample loading assembly, 11-Tube body, 111-Tube cavity, 112-First opening, 113-Second opening, 12-Plug, 13-Connector, 131-Flow channel, 132-First channel, 133-Second channel, 14-Fluid chamber;

[0035] 20-Adapter;

[0036] 30 - Sampling execution agency;

[0037] 40-Staff;

[0038] X - First direction, L - Axis of the joint, α - Included angle. Detailed Implementation

[0039] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only a part of the embodiments of the present invention, and not all of them. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0040] It should be noted that when a component is said to be "fixed" to another component, it can be directly on the other component or it can be in a middle component. When a component is said to be "connected" to another component, it can be directly connected to the other component or it may be in a middle component.

[0041] Unless otherwise defined, all technical and scientific terms used in this invention have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. The terminology used in this specification is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The term "and / or" as used in this invention includes any and all combinations of one or more of the associated listed items.

[0042] The following detailed description, in conjunction with the accompanying drawings, outlines some embodiments of the present invention. Unless otherwise specified, the following embodiments and features can be combined with each other.

[0043] Please refer to Figures 1 to 3 This utility model provides an experimental device, including a sample loading component 10 as described in this utility model embodiment, or a sample loading device 100 as described in this utility model embodiment. The sample loading device 100 includes a sample loading actuator 30 and the sample loading component 10 as described in this utility model embodiment. The sample loading actuator 30 is used to connect to the sample loading component 10 and to introduce fluid into the sample loading component 10.

[0044] Optionally, the experimental apparatus also includes a transport device connected to the sample application assembly 10 or the sample application device 100. When the experimental apparatus includes the sample application device 100, the transport device is connected to the sample application actuator 30 or other parts of the sample application device 100. The transport device moves the sample application device 100 so that the sample application actuator 30 of the sample application device 100 is connected to the sample application assembly 10; and / or, the transport device moves the sample application device 100 from an initial position to a target position so that the sample application assembly 10 performs a sample injection operation at the initial position and a sample dispensing operation at the target position; and / or, the transport device moves the sample application device 100 to a recovery position to detach the sample application assembly 10 from the sample application actuator 30.

[0045] The conveying device can be a multi-axis robotic arm, such as a four-axis robotic arm or a six-axis robotic arm, or an XYZ three-axis moving mechanism; there is no limitation here. The conveying device and the sample dispensing device 100 can be fixedly connected, such as by screwing, gluing, or welding; the conveying device and the sample dispensing device 100 can also be detachably connected, such as by magnetic attraction or pneumatic connection.

[0046] In one implementation, such as Figure 1 and Figure 2As shown, the sample application device 100 also includes an adapter 20 for connecting to a transport device.

[0047] The specific shape of the adapter 20 can be determined by any feasible solution, and this embodiment of the utility model does not impose any limitations.

[0048] The adapter 20 and the sample application device 100 can be an integrated structure or a separate structure, without restriction.

[0049] The adapter 20 can be connected to the conveying device via pneumatic connection, screw connection, snap-fit ​​connection, magnetic connection, etc., without limitation. Preferably, the adapter 20 is connected to the conveying device via pneumatic connection, the adapter 20 is a quick-change female connector, and the conveying device is equipped with a quick-change male connector, so that the two can be quickly loaded and unloaded.

[0050] The adapter 20 provided in the sample dispensing device 100 helps to improve the flexibility of the sample dispensing device 100 and broaden the scope of its application.

[0051] When the experimental equipment includes the sample loading component 10, the transport device and the sample loading component 10 can be connected by means of screwing, snap-fitting, gluing, magnetic attraction, clamping, etc., without any restrictions.

[0052] The experimental equipment of this utility model embodiment, by adopting the sample addition component 10 or the sample addition device 100 in this utility model embodiment, can perform a variety of operations to improve the level of automation and reduce the residue of transferred samples.

[0053] The sample addition component 10 in the embodiments of this utility model will be described in detail below.

[0054] First, define the direction. Please refer to [the relevant documentation / reference]. Figures 1 to 3 X is the first direction X. Optionally, when the sample application component 10 is in use, the first direction X can be the direction of gravity (suitable for vertical sample application scenarios), or the first direction X can be at a certain angle to the direction of gravity (suitable for inclined sample application scenarios), without restriction.

[0055] Please refer to Figures 1 to 3 This invention provides a sample dispensing assembly 10, including a tube body 11, a plug 12, and a connector 13. The tube body 11 has a hollow cavity 111 and opposing first openings 112 and 113, both of which communicate with the cavity 111. The plug 12 is located at one end of the tube body 11 and is used to close the second opening 113, allowing the cavity 111 to accommodate the sample to be transferred. The connector 13 is located at the end of the tube body 11 away from the plug 12 and closes the first opening 112. The connector 13 has a flow channel 131 that communicates with the cavity 111 to allow fluid to flow into the cavity 111.

[0056] When the air pressure in the cavity 111 is greater than the preset value, the plug 12 separates from the tube body 11 to unseal the second opening 113.

[0057] The tube body 11 can be roughly cylindrical, conical, prismatic, etc., without limitation. The tube body 11 can be made of corrosion-resistant and stable metallic or non-metallic materials. For example, metallic materials can be Hastelloy, titanium alloy, 316L stainless steel, 304 stainless steel, etc., without limitation; non-metallic materials can be polyethylene (PE), polypropylene (PP), polytetrafluoroethylene (PTFE), polyvinylidene fluoride (PVDF), glass, ceramics, etc., without limitation. Optionally, the tube body 11 can be manufactured using a mold, and different materials can be used for different working conditions to avoid reaction between the tube body 11 and the sample to be transferred.

[0058] The fluid can be a gas, preferably nitrogen or an inert gas (such as helium, argon, etc.), to avoid chemical reactions with the sample; the fluid can also be an ion wind, which can eliminate static electricity in the lumen 111 and reduce sample adsorption on the inner wall of the lumen 111.

[0059] Optionally, the wall thickness of the four side walls of the tube 11 is approximately the same. The tube 11 has an axis of symmetry extending along a first direction X, and the tube 11 is approximately symmetrical with respect to this axis of symmetry.

[0060] The plug 12 can be completely or at least partially contained within the lumen 111, sealing the second opening 113 from within the lumen 111; or, the plug 12 can also be disposed on the outside of the pipe body 11, sealing the second opening 113 from outside the pipe body 11, without any specific limitation.

[0061] After the plug 12 seals the second opening 113, the solid sample to be transferred (such as a powder sample, a granular sample, etc.) can be added into the tube body 11 through the first opening 112. Then, the connector 13 is assembled to the end of the tube body 11 away from the plug 12 and the first opening 112 is sealed to avoid external contamination.

[0062] The connector 13 can adopt any feasible structure in the art that has a flow channel 131 and can play a sealing role, and there is no specific limitation. Optionally, the extension direction of the flow channel 131 can be any one or a combination of straight lines, broken lines or curves, and there is no specific limitation.

[0063] In one embodiment, the flow channel 131 may extend along a first direction X, and the sample dispensing assembly 10 further includes a flow control valve, which is connected to the flow channel 131. By setting the flow control valve to control the fluid velocity flowing from the flow channel 131 into the cavity 111, the sample in the cavity 111 is prevented from being stirred up.

[0064] When it is necessary to separate the plug 12 from the tube body 11, fluid can be introduced into the tube body 11 through the flow channel 131 of the connector 13 to increase the gas pressure in the tube cavity 111. The gas pressure in the tube cavity 111 gradually increases. When the gas pressure in the tube cavity 111 is greater than a preset value, that is, when the pressure exerted by the gas in the tube cavity 111 on the plug 12 is greater than the frictional force between the plug 12 and the tube body 11, the plug 12 separates from the tube body 11 to unseal the second opening 113, and the sample in the tube cavity 111 can be ejected from the second opening 113 into the reaction vessel.

[0065] Understandably, because the plug 12 provides some resistance within the tube 11, the pressure inside the tube 11 becomes greater than the external atmospheric pressure after fluid is introduced. By adjusting the fit clearance between the plug 12 and the tube 11, the internal pressure of the tube 11 can be effectively regulated, achieving positive pressure powder feeding. The higher pressure inside the tube 11 allows the powder to aggregate more tightly. When the plug 12 pops out, the significant pressure difference between the inside and outside causes the solid sample inside the tube 11 to be ejected quickly, reducing its adhesion to the inner wall of the tube 11.

[0066] The sample loading assembly 10 in this embodiment of the present invention comprises a tube body 11, a plug 12, and a connector 13. The plug 12 is located at one end of the tube body 11 and seals the second opening 113 of the tube body 11. When it is necessary to unseal the second opening 113, fluid is introduced into the tube cavity 111 through the connector 13 located at the first opening 112, so that the air pressure in the tube cavity 111 is greater than a preset value, thereby separating the plug 12 from the tube body 11 and allowing the sample to be transferred in the tube cavity 111 to be ejected. No manual operation is required for sample loading, which simplifies the sample loading process and improves experimental efficiency. At the same time, under the action of air pressure, the sample in the tube body 11 is ejected quickly, reducing sample residue and improving experimental accuracy. In addition, since no manual intervention is required, experimental safety is improved and it is conducive to automated integration.

[0067] In one embodiment, such as Figure 2 and Figure 3 As shown, the tube body 11 has an axis extending along the first direction X, the first opening 112 and the second opening 113 are opposite each other in the first direction X, and the connector 13 has an axis extending along the first direction X.

[0068] Optionally, the connector 13 is approximately centrally symmetrical along its axis, and the axis L of the connector 13 can be collinear with the axis of the tube body 11, that is, their axes of symmetry coincide. With this configuration, the sample feeding assembly 10 is axially symmetrical, with a simple structure, easy implementation, and facilitates quick docking of the connector 13 and the tube body 11.

[0069] Optionally, the flow channel 131 extends along the first direction X, and the axis of the flow channel 131 coincides with the axis of the connector 13, making the flow channel 131 easy to process.

[0070] Optionally, the flow channel 131 includes a first channel 132 and a second channel 133, the first channel 132 extending along a first direction X, and the second channel 133 connecting the first channel 132 and the lumen 111.

[0071] Optionally, the first channel 132 is located approximately on the axis L of the connector 13.

[0072] Optionally, the opening at the end of the second channel 133 away from the first channel 132 can be located on the side wall of the connector 13 or on the surface of the connector 13 facing the plug 12, without limitation.

[0073] In one embodiment, the opening of the second channel 133 away from the first channel 132 is located on the side wall of the connector 13, and the fluid can enter the lumen 111 from the side wall of the connector 13, avoiding the direct blowing of fluid and causing the sample in the lumen 111 to be stirred up, thereby reducing sample residue.

[0074] In one embodiment, the extension direction of the second channel 133 forms an angle α with the first direction X, satisfying: 30° ≤ α ≤ 150°. Optionally, the angle α can be 30°, 45°, 60°, 80°, 90°, 100°, 110°, 120°, 125°, 130°, 140°, 145°, 150°, etc., without limitation. This setting can prevent the fluid from blowing directly onto the sample from the second channel 133, thus avoiding the sample being lifted up.

[0075] By setting the flow channel 131 to include a first channel 132 and a second channel 133, and the extension direction of the second channel 133 having an angle α with the first direction X, the direction of fluid flowing into the cavity 111 can be changed, avoiding the fluid blowing directly onto the sample contained in the cavity 111, and improving the sample being lifted due to fluid impact.

[0076] In one specific embodiment, such as Figure 3 As shown, the second channel 133 extends radially along the connector 13. The angle between the extension direction of the second channel 133 and the radial direction of the connector 13 can be considered 0°, and the angle α between the extension direction of the second channel 133 and the first direction X is equal to 90°. With this configuration, the fluid flow distance is shorter.

[0077] Understandably, the second channel 133 extends radially along the connector 13, meaning that the connector 13 has a circular radial section perpendicular to the first direction X, the axis of the second channel 133 is located within this radial section, and the axis of the second channel 133 intersects and is perpendicular to the axis of the connector 13.

[0078] In another specific embodiment, such as Figure 4As shown, the second channel 133 extends tangentially along the radial section of the connector 13, and the angle α between the extension direction of the second channel 133 and the first direction X is equal to 90°. With this configuration, the fluid flow distance is shorter.

[0079] Understandably, the second channel 133 extends tangentially along the radial section of the connector 13, that is, the connector 13 has a circular radial section perpendicular to the first direction X, the axis of the second channel 133 is located in the radial section, and the axis of the second channel 133 is parallel to the tangential direction of the radial section.

[0080] In another specific embodiment, the second channel 133 extends toward the second opening 113, and the included angle α satisfies: 90°<α≤150°.

[0081] Optionally, the included angle α can be 95°, 100°, 110°, 120°, 125°, 130°, 140°, 145°, 150°, etc., without restriction. When the included angle α is too large, the fluid entering from the second channel 133 still risks directly blowing onto the sample. When the included angle α is within the range of 90° < α ≤ 150°, the fluid flowing out from the second channel 133 can flow along the four walls of the tube 11, avoiding the fluid directly blowing onto the sample and causing the sample to be stirred up.

[0082] In one embodiment, such as Figure 3 As shown, there are multiple second channels 133, and the openings of the multiple second channels 133 on the side wall of the connector 13 are distributed at intervals along the circumference of the connector 13. All of the multiple second channels 133 are connected to the first channel 132.

[0083] It is understood that "multiple" in the embodiments of this application refers to two or more.

[0084] Optionally, the inner diameter of the first channel 132 and the inner diameter of the second channel 133 can be approximately the same. This arrangement facilitates the smooth flow of fluid and prevents it from accumulating at the connection between the first channel 132 and the second channel 133.

[0085] Optionally, the inner diameter of each second channel 133 can be approximately the same and can all be smaller than the inner diameter of the first channel 132. This design allows the fluid in the first channel 132 to enter each second channel 133 more evenly.

[0086] Optionally, the openings of the multiple second channels 133 on the side wall of the connector 13 can be distributed at equal intervals along the circumference of the connector 13, and the spacing between the openings of two adjacent second channels 133 on the side wall of the connector 13 can also be different, without any specific limitation.

[0087] With this configuration, the fluid can be dispersed from all sides of the connector 13, and the fluid flow is relatively uniform, which can effectively prevent airflow disturbance from causing the solid sample in the cavity 111 to be thrown up.

[0088] In one embodiment, the plug 12 is slidably connected to the pipe body 11, and the outer peripheral surface of the plug 12 is either interference-fitted or transition-fitted to the inner wall of the pipe cavity 111.

[0089] Optionally, the plug 12 may be wholly or at least partially housed within the lumen 111. The outer peripheral surface of the plug 12 may be in line contact or surface contact with the inner wall of the lumen 111, and there is no specific limitation.

[0090] Optionally, the outer circumferential surface of the plug 12 is interference-fitted with the inner wall of the lumen 111, meaning that the dimensional tolerance zone of the tube body 11 at the second opening 113 is completely below the dimensional tolerance zone of the plug 12 (the maximum limit dimension of the tube body 11 at the second opening 113 is less than the minimum limit dimension of the plug 12). With this configuration, when no gas is introduced into the lumen 111 to change the gas pressure inside the lumen 111, the interference fit between the plug 12 and the tube body 11 ensures that the plug 12 will not separate from the tube body 11, guaranteeing the reliability of the sample loading assembly 10 in holding the sample.

[0091] Alternatively, the outer circumferential surface of the plug 12 can be fitted with the inner wall of the lumen 111, meaning that the dimensional tolerance zone of the tube body 11 at the second opening 113 partially overlaps with the dimensional tolerance zone of the plug 12 (the maximum limit dimension of the tube body 11 at the second opening 113 is greater than or equal to the minimum limit dimension of the plug 12, and the maximum limit dimension of the plug 12 is greater than or equal to the minimum limit dimension of the tube body 11 at the second opening 113). With this configuration, while ensuring that the plug 12 will not separate from the tube body 11 during sample transfer, the frictional force required to separate them is relatively small. Introducing a suitable amount of fluid into the lumen 111 is sufficient to separate the plug 12 from the tube body 11 to unseal the second opening 113, facilitating operation.

[0092] In one embodiment, the outer peripheral surface of the plug 12 that contacts the lumen 111 is a smooth, convex curved surface.

[0093] Optionally, the plug 12 is housed within the cavity 111 and contacts the inner wall of the cavity 111 to seal the second opening 113.

[0094] Optionally, the shape of the plug 12 can be any one of spherical, hemispherical, ellipsoidal and olive-shaped, or any other feasible shape, without any specific limitation.

[0095] With this configuration, the plug 12 is in line contact with the inner wall of the tube 11. Compared with surface contact (e.g., the plug 12 is block-shaped or columnar), it is easier to overcome the friction between the plug 12 and the inner wall of the tube 11. The plug 12 is easy to separate from the tube 11 to unseal the second opening 113.

[0096] In one embodiment, the sample feeding assembly 10 further includes a connector (not shown) located at one end of the tube body 11 near the second opening 113 and connecting the plug 12 and the tube body 11.

[0097] The connector can be located inside the cavity 111 of the tube body 11, or it can be set on the outer peripheral surface of the tube body 11, or it can be set on the bottom wall of the tube body 11 located at the second opening 113. There are no specific restrictions.

[0098] Optionally, when the plug 12 is separated from the tube body 11, the connector is connected to the plug 12 to prevent the plug 12 from falling into the reaction vessel after the second opening 113 is unsealed. The connector can be an elastic component (such as a plastic strip or rubber strip with a certain degree of elasticity) or a rigid component (such as a shaft or hinge), and there are no specific restrictions.

[0099] In one specific embodiment, the plug 12 is rotatably connected to the pipe body 11, and the connector is used to make the plug 12 rotate relative to the pipe body 11.

[0100] One end of the connector is connected to the tube body 11, and the other end is connected to the plug 12. The connector can rotate around the end connected to the tube body 11. When the air pressure in the cavity 111 is greater than a preset value, the plug 12 detaches from the tube body 11 at the second opening 113. At this time, the connector, tube body 11, and plug 12 are similar to a flip-open structure. When the plug 12 detaches, it drives the connector to rotate around the tube body 11 to avoid the second opening 113, so as to facilitate the ejection of the sample in the cavity 111. At the same time, the connector connects the plug 12 to the tube body 11 to prevent the plug 12 from falling off.

[0101] By setting a connector that connects the plug 12 and the tube 11, the plug 12 can be rotated relative to the tube 11, thus preventing the plug 12 from falling into the reaction vessel and affecting subsequent experiments.

[0102] In one embodiment, the plug 12 is made of any one of polytetrafluoroethylene, ceramic, Hastelloy, or titanium alloy. This design allows for selection of the appropriate plug 12 material based on the characteristics of the sample to be transferred, preventing the plug 12 from reacting with the sample and adapting to different operating conditions. Furthermore, when the plug 12 is slidably connected to the tube body 11 and falls into the reaction container after being unsealed from the second opening 113, limiting the material of the plug 12 can prevent it from reacting with the reaction liquid in the reaction container and affecting the purity of the product; after the reaction, the plug 12 can be separated simply by filtering the reaction liquid. Additionally, even if the plug 12 does not fall into the reaction container, its proximity to the reaction liquid may still cause corrosion due to splashing; limiting the material of the plug 12 can extend its service life.

[0103] In one embodiment, the connector 13 and the pipe body 11 are detachably connected, specifically by insertion, snap-fit, screw connection, etc., without limitation. Optionally, a portion of the connector 13 is inserted into the pipe body 11, and the outer peripheral surface of the connector 13 is interference-fitted or transition-fitted with the inner wall of the pipe cavity 111; or, the connector 13 is placed on the pipe body 11, and the inner wall surface of the connector 13 is threadedly connected to the outer peripheral surface of the pipe body 11.

[0104] In one embodiment, the inner diameter of the tube body 11 remains constant or gradually decreases in the direction from the first opening 112 to the second opening 113.

[0105] Optionally, the shape of the sidewall of the lumen 111 can be approximately cylindrical or conical, facilitating smooth sample flow and reducing sample residue within the lumen 111. Optionally, the inner diameter of the tube 11 can decrease uniformly, abruptly, or non-uniformly in the direction from the first opening 112 to the second opening 113; no specific limitation is imposed. For example, the portion near the first opening 112 can be cylindrical, and the portion near the second opening 113 can be conical, with a smooth transition between the two parts. This facilitates both the connection of the connector 13 to the tube 11 and sample flow.

[0106] Optionally, the wall thickness of the tube 11 can be approximately uniform, that is, the change in the outer diameter of the tube 11 is consistent with the change in the inner diameter of the tube 11 in the direction from the first opening 112 to the second opening 113; or, the outer diameter of the tube 11 is consistent in the direction from the first opening 112 to the second opening 113, while the inner diameter of the tube 11 gradually decreases, and there is no specific limitation.

[0107] This setup reduces sample residue in lumen 111, ensuring experimental accuracy while avoiding waste.

[0108] Please refer to Figures 1 to 3 The present invention provides a sample feeding device 100, including a sample feeding execution mechanism 30 and the aforementioned sample feeding component 10. The sample feeding execution mechanism 30 is used to connect to the sample feeding component 10 and to introduce fluid into the sample feeding component 10.

[0109] The sample feeding actuator 30 can be connected to the flow channel 131 of the connector 13 through a conduit to introduce fluid into the flow channel 131; or the sample feeding actuator 30 can be directly connected to the connector 13 to connect to the flow channel 131 to introduce fluid into the flow channel 131. There are no specific restrictions.

[0110] In one embodiment, such as Figure 1 and Figure 2 As shown, connector 13 is fixedly connected to sample feeding actuator 30, and connector 13 is detachably connected to tube body 11.

[0111] Optionally, the sample application device 100 includes a support 40, and the sample application actuator 30 is disposed on the support 40. The two can be connected by welding, bonding, snap-fitting, screwing, or other means, without limitation.

[0112] Optionally, connector 13 can be directly connected to the sample dispensing actuator 30. Connector 13 can be fixed to the sample dispensing actuator 30 by welding, bonding, snap-fitting, screwing, riveting, magnetic connection, etc., and there are no specific restrictions. Optionally, connector 13 can be indirectly connected to the sample dispensing actuator 30. Connector 13 can be connected to the sample dispensing actuator 30 through a conduit.

[0113] The detachable connection between the connector 13 and the pipe body 11 can be a plug-in, snap-fit, screw-in, etc., without limitation. Optionally, a portion of the connector 13 is inserted into the pipe body 11, and the outer circumferential surface of the connector 13 is interference-fitted or transition-fitted with the inner wall of the pipe cavity 111; or, the connector 13 is placed on the pipe body 11, and the inner wall surface of the connector 13 is threadedly connected to the outer circumferential surface of the pipe body 11.

[0114] Since different materials of pipe body 11 may be required for operation under different working conditions, the connector 13 is detachably connected to the pipe body 11, which can flexibly adapt to different working conditions.

[0115] The following describes the specific workflow of the sample loading device 100: First, the plug 12 is inserted into the tube body 11 to seal the second opening 113. The sample to be transferred is then added to the tube body 11 manually or using a specialized sample loading device (i.e., sample loading operation). Next, the loading actuator 30 is manually or via a handling device (such as a robotic arm) to connect the connector 13 to the tube body 11, and the tube body 11 is moved so that the second opening 113 is aligned with the reaction vessel to which the sample is to be loaded. Then, fluid is introduced into the lumen 111 through the connector 13. The air pressure inside the lumen 111 gradually increases. When the pressure exceeds the frictional force between the plug 12 and the tube body 11, the plug 12 separates from the tube body 11, and the sample inside the tube body 11 is ejected into the reaction vessel, completing the sample loading (i.e., sample ejection operation).

[0116] In one embodiment, such as Figure 2 As shown, the sample feeding actuator 30 also includes a fluid chamber 14, which contains fluid; the connector 13 connects the fluid chamber 14 and the lumen 111 to allow the fluid in the fluid chamber 14 to be fed into the lumen 111.

[0117] The fluid chamber 14 is used to provide fluid flowing into the lumen 111. Optionally, the fluid chamber 14 can be integrated with the connector 13, in which case the fluid chamber 14 and the connector 13 can be connected and fixed by means of welding, bonding, snap-fitting, screwing, riveting, magnetic connection, etc.; or, the fluid chamber 14 can also be an external device that can provide fluid (such as a compressed air tank, etc.), and there is no specific limitation.

[0118] The sample feeding actuator 30 also includes a switching valve, which connects to the connector 13 and the fluid chamber 14. The switching valve controls the connection or disconnection between the connector 13 and the fluid chamber 14. When it is necessary to introduce fluid into the chamber 111 to increase the gas pressure inside the pipe, the switching valve opens to allow fluid to flow into the chamber 111. The switching valve can be a ball valve, gate valve, globe valve, diaphragm valve, or any other feasible valve structure; no specific restrictions are imposed.

[0119] Optionally, the sample feeding actuator 30 may also include a flow control valve, which is connected to the on / off valve and the connector 13, or the flow control valve is connected to the fluid chamber 14 and the on / off valve. The flow control valve is used to control the flow rate of the fluid flowing into the connector 13.

[0120] Flow control valves are used to regulate and control the flow rate of fluids by changing the flow area of ​​the valve orifice or the length of the channel. Optionally, flow control valves can be throttle valves, velocity valves, constant flow valves, or any other feasible flow regulation structure, without limitation.

[0121] When fluid needs to be introduced into the cavity 111 through the connector 13, the switch valve is opened to connect the fluid chamber 14 and the connector 13. The flow rate of the air flowing into the cavity 111 through the switch valve can be controlled in real time by the flow control valve so that the fluid can flow into the cavity 111 smoothly and avoid the airflow impacting the sample and causing the sample to be thrown up.

[0122] In one embodiment, the fluid chamber 14 is fixedly connected to the connector 13 and located at the end of the connector 13 away from the plug 12; the fluid chamber 14 contains a fixed amount of fluid, and the flow channel 131 connects the fluid chamber 14 and the cavity 111 so as to pass the fixed amount of fluid in the fluid chamber 14 into the cavity 111.

[0123] The fluid chamber 14 and the connector 13 can be an integral structure or a separate structure, without limitation. The fluid chamber 14 can be a cylindrical fluid chamber, a membrane fluid chamber, or any other feasible fluid chamber 14 structure, without limitation.

[0124] By setting the fluid chamber 14 to contain a fixed amount of fluid, when the friction between the plug 12 and the tube body 11 is small, the fixed amount of fluid in the fluid chamber 14 can be introduced into the tube cavity 111 to separate the plug 12 and the tube body 11, and unseal the second opening 113, thus avoiding fluid waste; and by integrating the fluid chamber 14 into the connector 13, external equipment (such as compressed air tanks) is avoided, and the integration of the sample dispensing component 10 and the sample dispensing device 100 is improved.

[0125] Understandably, the fluid chamber 14 is integrated on the connector 13, and the fluid chamber 14 can be regarded as a component of the sample feeding assembly 10, further enriching the function of the sample feeding assembly 10.

[0126] In one embodiment, the sample dispensing mechanism 30 also integrates a quick-release mechanism for separating the connector 13 from the tube body 11. After the sample dispensing is completed, the quick-release mechanism can be used to detach the tube body 11 from the connector 13 so that the connector 13 can be connected to the next tube body 11 for the next round of sample dispensing, or to facilitate cleaning of the tube body 11 or the connector 13.

[0127] In one embodiment, the sample addition device 100 further includes a liquid addition mechanism, which is used to communicate with the connector 13 and inject cleaning liquid or reaction liquid into the tube body 11 through the connector 13.

[0128] Optionally, the liquid addition mechanism includes a liquid addition pump and a multi-way valve. The liquid addition pump, the container holding the liquid, and the connector 13 are all connected to the multi-way valve to pump the cleaning solution or reaction solution into the pipe body 11 through the connector 13. The liquid addition pump can be a plunger pump, diaphragm pump, peristaltic pump, piston pump, etc., or any feasible device for conveying liquids in the art, without specific limitations. The multi-way valve can be a solenoid valve or any other feasible valve structure, without specific limitations.

[0129] After the sample in the sample loading assembly 10 has been transferred to the reaction container, the tube 11 of the sample loading assembly 10 needs to be cleaned. At this time, cleaning fluid can be injected into the tube 11 through the liquid loading mechanism to clean the residual sample in the tube 111. The cleaned liquid can flow into the reaction container as a reaction solution or be discharged to the waste liquid pool. Alternatively, other reaction solutions can be added to the reaction container through the liquid loading mechanism and the sample loading assembly 10. In this case, during liquid loading, the multi-way valve connects the liquid loading pump, the reaction solution, and the connector 13 respectively. The liquid loading pump pumps the reaction solution into the reaction container through the connector 13. No additional liquid loading device is required, which is convenient for operation.

[0130] By setting up the above-mentioned liquid addition mechanism, cleaning solution or reaction solution can be added into the tube 11 to clean the tube 111 or add reaction solution into the reaction container. No manual operation or additional liquid addition device is required, which can improve experimental efficiency and experimental safety.

[0131] Optionally, the liquid adding mechanism can add liquid into the tube body 11 through the flow channel 131 of the connector 13, or a special liquid adding channel can be set in the connector 13, the liquid adding mechanism is connected to the liquid adding channel, and the cleaning liquid or reaction liquid is injected into the tube body 11 through the liquid adding channel, and there are no specific restrictions.

[0132] In one embodiment, the connector 13 further has a liquid filling channel that connects the liquid filling mechanism and the cavity 111. The liquid filling channel includes a third channel and a fourth channel. The third channel is connected to the liquid filling mechanism, and the fourth channel is connected to the third channel and the cavity 111. One end of the fourth channel is located on the side wall of the connector 13.

[0133] Optionally, the liquid filling channel and the flow channel 131 are spaced apart. The liquid filling channel and the flow channel 131 may be approximately symmetrical along the axis L of the connector 13; or, the flow channel 131 may be approximately located at the axis L of the connector 13, and the liquid filling channel may be located on one side of the flow channel 131.

[0134] Optionally, the third channel may extend generally along the first direction X, and the fourth channel connects the third channel to the lumen 111. Optionally, the fourth channel may extend radially along the connector 13 or have a certain angle with the radial direction of the connector 13, without limitation.

[0135] Optionally, there are multiple fourth channels, and the openings of the multiple fourth channels on the side wall of the connector 13 are distributed at intervals along the circumference of the connector 13, and the multiple fourth channels are all connected to the third channel.

[0136] The specific settings for the liquid addition channel can be found in the aforementioned flow channel 131, and will not be repeated here.

[0137] By setting up a liquid addition channel, the liquid addition mechanism injects cleaning liquid or reaction liquid into the tube 11 through the liquid addition channel. The liquid addition channel and the flow channel 131 are set separately to avoid mutual contamination.

[0138] In one embodiment, the sample application device 100 further includes a liquid extraction mechanism, which is used to communicate with the connector 13 and to create a negative pressure in the cavity 111 so that liquid enters the cavity 111 through the second opening 113, and to create a positive pressure in the cavity 111 so that liquid in the cavity 111 is discharged through the second opening 113.

[0139] Optionally, the liquid extraction mechanism includes a liquid extraction drive, a piston cylinder, and a piston. The piston cylinder has a receiving cavity, and the piston is housed in the receiving cavity. The liquid extraction drive is connected to the piston to drive the piston to move in the receiving cavity. The connector 13 is connected to one end of the piston cylinder, and the flow channel 131 connects the receiving cavity and the tube 111.

[0140] With this configuration, the positive or negative pressure generated by the piston moving in the containment cavity can be transmitted to the lumen 111 through the connector 13. When the lumen 111 is under negative pressure, the reaction liquid in the reaction container can be drawn through the second opening 113, and the reaction liquid enters the lumen 111 and comes into contact with the residual sample. When the lumen 111 is under positive pressure, the reaction liquid in the lumen 111 can be driven to flow out from the second opening 113, which can clean the residual sample in the lumen 111, improve the accuracy of the experiment, and avoid sample waste.

[0141] In the description of the embodiments of this utility model, it should be noted that the orientation or positional relationship of the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer" and other indicators are based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this utility model and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model.

[0142] The above-disclosed embodiments are merely preferred embodiments of the present utility model and should not be construed as limiting the scope of the present utility model. Those skilled in the art can understand that implementing all or part of the above-described embodiments and making equivalent changes in accordance with the claims of the present utility model are still within the scope of the present utility model.

Claims

1. A sample dispensing assembly, characterized in that, include: The tube has a hollow cavity and a first opening and a second opening, both of which are in communication with the cavity. A plug is disposed at one end of the tube and is used to close the second opening so that the tube can accommodate the sample to be transferred; A connector is disposed at the end of the pipe body away from the plug and is used to close the first opening. The connector has a flow channel that communicates with the pipe cavity to allow fluid to flow into the pipe cavity. When the air pressure inside the cavity is greater than a preset value, the plug separates from the tube body to unseal the second opening.

2. The sample dispensing assembly according to claim 1, characterized in that, The tube body has an axis extending along a first direction, and the first opening and the second opening are opposite each other in the first direction; the connector has an axis extending along the first direction, and the axis of the connector is collinear with the axis of the tube body. The flow channel includes a first channel and a second channel. The first channel extends along the first direction, and the second channel connects the first channel and the lumen. The extension direction of the second channel has an angle α with the first direction, satisfying: 30°≤α≤150°.

3. The sample dispensing assembly according to claim 2, characterized in that, The opening at the end of the second channel away from the first channel is located on the side wall of the connector; The second channel extends radially along the connector, or the second channel extends tangentially along the radial cross-section of the connector, or the second channel extends toward the second opening; The included angle α satisfies: 90°≤α≤150°.

4. The sample dispensing assembly according to claim 2, characterized in that, There are multiple second channels, and the openings of the multiple second channels on the side wall of the connector are distributed at intervals along the circumference of the connector, and all of the multiple second channels are connected to the first channel.

5. The sample dispensing assembly according to claim 1, characterized in that, The plug is slidably connected to the pipe body, and the outer peripheral surface of the plug is either interference-fitted or transition-fitted to the inner wall of the pipe cavity.

6. The sample dispensing assembly according to claim 5, characterized in that, The outer peripheral surface of the plug that contacts the cavity is a smooth, convex curved surface.

7. The sample dispensing assembly according to claim 1, characterized in that, The sample dispensing assembly also includes a connector located at one end of the tube body near the second opening, and connecting the plug and the tube body; The plug is rotatably connected to the pipe body; the connector is used to allow the plug to rotate relative to the pipe body.

8. The sample dispensing assembly according to claim 1, characterized in that, The plug is made of any one of polytetrafluoroethylene, ceramic, Hastelloy, or titanium alloy.

9. The sample dispensing assembly according to any one of claims 1-8, characterized in that, The connector is detachably connected to the pipe body; The inner diameter of the tube remains constant or gradually decreases in the direction from the first opening to the second opening.

10. A sample dispensing device, characterized in that, It includes a sample dispensing actuator and a sample dispensing assembly as described in any one of claims 1 to 9, wherein the sample dispensing actuator is configured to connect to the sample dispensing assembly and to introduce fluid into the sample dispensing assembly.

11. The sample dispensing device according to claim 10, characterized in that, The connector is fixedly connected to the sample feeding mechanism, and the connector is detachably connected to the tube body.

12. The sample dispensing device according to claim 11, characterized in that, The sampling actuator includes a fluid chamber containing fluid; the connector connects the fluid chamber to the lumen to allow the fluid in the fluid chamber to flow into the lumen. The sample dispensing actuator also includes a switching valve, which connects the connector and the fluid chamber, and is used to control the connection or disconnection between the connector and the fluid chamber.

13. The sample addition device according to claim 12, characterized in that, The fluid chamber is fixedly connected to the connector and located at the end of the connector away from the plug; the fluid chamber contains a fixed amount of fluid, and the flow channel connects the fluid chamber and the lumen to allow the fixed amount of fluid in the fluid chamber to be introduced into the lumen.

14. The sample dispensing apparatus according to any one of claims 10-13, characterized in that, The sample addition device also includes a liquid addition mechanism, which is used to communicate with the connector and inject cleaning solution or reaction solution into the tube through the connector.

15. The sample dispensing device according to claim 14, characterized in that, The connector also has a liquid filling channel, which connects the liquid filling mechanism and the cavity; The liquid filling channel includes a third channel and a fourth channel. The third channel is connected to the liquid filling mechanism, and the fourth channel is connected to the third channel and the lumen. One end of the fourth channel is located on the side wall of the connector.

16. The sample dispensing apparatus according to any one of claims 10-13, characterized in that, The sample application device further includes a liquid extraction mechanism, which is used to communicate with the connector and to create a negative pressure in the lumen so that liquid enters the lumen through the second opening, and to create a positive pressure in the lumen so that liquid in the lumen is discharged through the second opening.

17. An experimental apparatus, characterized in that, It includes the sample dispensing component as described in any one of claims 1 to 9, or the sample dispensing device as described in any one of claims 10 to 16.

18. The experimental apparatus according to claim 17, characterized in that, The experimental equipment also includes a transport device, which is connected to the sample application assembly or the sample application device and is used to move the components thereon.

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