A sampling device for biological product development

Abstract

The utility model provides a kind of sampling equipment for biological product research and development, it is related to sampling equipment technical field, including: cabinet, gantry is fixedly installed in cabinet top, placing plate is fixedly installed in cabinet top, frame is equipped on placing plate, sampling needle cylinder is equipped in the inside of frame.This kind of sampling equipment can control sampling needle cylinder to sample by sampling mechanism, so it is unnecessary to sample manually, then be transferred into collection sample bottle, sample collection process is more simple and convenient, improve the stability of sampling, avoid reagent to leak and spill in transfer way, improve the progress of experimental work.

Description

Technical Field

[0001] This utility model relates to the field of sampling equipment technology, specifically a sampling device for biological product research and development. Background Technology

[0002] In the process of bioproduct research and development, sampling is a key step in obtaining experimental data, evaluating the characteristics of biomaterials, monitoring biological reaction processes, and ensuring product quality. Traditional sampling methods mostly rely on manual operation or simple mechanical devices, which have problems such as cumbersome operation, low sampling efficiency, easy sample contamination, and poor repeatability. Especially in experiments with strict requirements for sterile environment, micro-samples, or high-throughput sample collection, traditional methods are difficult to meet the high standards of modern bio-research. In the existing sampling equipment technology, technicians generally use a handheld syringe to draw up liquid samples and transfer them to reagent bottles. This is unstable, and reagents are prone to leakage due to vibration and collision during transfer, which delays the progress of the experiment by requiring resampling. Utility Model Content

[0003] The purpose of this application is to provide a sampling device for biological product research and development, so as to solve the technical problems of unstable manual sampling and easy leakage during the transfer process in the prior art.

[0004] To achieve the above objectives, the technical solution adopted in this application is: to provide a sampling device for biological product research and development, comprising: a cabinet, a gantry frame fixedly installed on the top of the cabinet, a placement plate fixedly installed on the top of the cabinet, a frame provided on the placement plate, and a sampling syringe provided inside the frame;

[0005] A sampling mechanism, which is mounted on the frame, is used to sample the sample. The sampling mechanism includes: a mounting groove, a drive motor, a lead screw, a screw block, a moving block, and a T-slot.

[0006] Furthermore, an installation groove is fixedly installed inside the frame, a drive motor is fixedly installed at the top of the installation groove, a lead screw is fixedly connected to the drive shaft at the bottom of the drive motor, the bottom end of the lead screw is rotatably connected to the bottom of the installation groove, a screw block is threaded to the outside of the lead screw, a moving block is fixedly connected to the front side of the screw block, and a T-shaped groove is opened on the front side of the moving block.

[0007] Furthermore, an installation plate is provided between the opposite sides of the gantry frame, a multi-axis linear guide rail is fixedly installed at the bottom of the installation plate, an electric push rod is fixedly installed at the top of the gantry frame, the output end of the bottom of the electric push rod is connected to the top of the installation plate, and the frame is fixedly installed on the multi-axis linear guide rail.

[0008] Furthermore, a limiting plate is fixedly connected to the front side of the frame, and placement grooves are provided on the front side of the limiting plate and the front side of the bottom of the frame.

[0009] Furthermore, two spring plates are fixedly connected to the bottom of each frame, and a pipe clamp plate is fixedly connected to the bottom end of each of the two spring plates.

[0010] Furthermore, the gantry frame has two sliding grooves on opposite sides, and a guide rod is fixedly connected between the top and bottom of the sliding groove. A slider is slidably connected to the outside of the guide rod, and the sliders on both sides are respectively connected to the opposite ends of the mounting plate.

[0011] The beneficial effects of this utility model are:

[0012] The advantage of this invention is that the sampling mechanism can control the sampling syringe to take samples, so there is no need to manually sample and then transfer the samples to the collection bottle. The sample collection process is simpler and more convenient, improving the stability of sampling, avoiding reagent leakage during transfer, and improving the progress of experimental work. Attached Figure Description

[0013] To more clearly illustrate the technical solutions in the embodiments of this application, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0014] Figure 1 This is a schematic diagram of the overall structure of this utility model.

[0015] Figure 2 This is a cross-sectional view of the overall structure of this utility model.

[0016] Figure 3 This is a schematic diagram of the frame structure of this utility model.

[0017] Figure 4 This is a schematic diagram of the mounting plate structure of this utility model.

[0018] Figure 5 For the present utility model Figure 2 Enlarged view of point A in the middle.

[0019] The following are the labeling elements in the figure:

[0020] 1. Cabinet; 11. Gantry frame; 12. Placement plate; 13. Frame; 14. Sampling syringe; 2. Mounting slot; 21. Drive motor; 22. Lead screw; 23. Screw block; 24. Moving block; 25. T-slot; 26. Limiting plate; 27. Placement slot; 28. Spring plate; 29. ​​Pipe clamp plate; 3. Mounting plate; 31. Multi-axis linear guide rail; 32. Electric push rod; 33. Slide groove; 34. Guide rod; 35. Slider. Detailed Implementation

[0021] To make the technical problems, technical solutions, and beneficial effects to be solved by this application clearer, the following detailed description is provided in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative and are not intended to limit the scope of this application.

[0022] It should be noted that when a component is referred to as being "fixed to" or "set on" another component, it can be directly on or indirectly on that other component. When a component is referred to as being "connected to" another component, it can be directly connected to or indirectly connected to that other component.

[0023] It should be understood that the terms "length", "width", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this application.

[0024] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this application, "multiple" means two or more, unless otherwise explicitly specified.

[0025] The present application will now be described in detail with reference to the accompanying drawings and specific embodiments.

[0026] Example 1

[0027] As attached Figures 1 to 5 The sampling device for biological product research and development shown includes: a cabinet 1, a gantry frame 11 fixedly installed on the top of the cabinet 1, a placement plate 12 fixedly installed on the top of the cabinet 1, a frame 13 provided on the placement plate 12, a sampling syringe 14 provided inside the frame 13, and a sampling mechanism located on the frame 13 for sampling samples.

[0028] In the process of developing biological products, when it is necessary to sample and test the developed products, the container holding the products is placed on the placement plate 12, and then the disposable sampling syringe 14 is placed on the sampling mechanism. The sampling mechanism can control the sampling syringe 14 to take samples, so there is no need to manually sample, which is more convenient.

[0029] Example 2

[0030] Based on Embodiment 1, the solution in Embodiment 1 will be further described in detail below with reference to the specific working method, such as... Figures 1 to 5 As shown below, see details:

[0031] The sampling mechanism includes: a mounting groove 2, a drive motor 21, a lead screw 22, a screw block 23, a moving block 24, and a T-slot 25. The mounting groove 2 is fixedly installed inside the frame 13. The drive motor 21 is fixedly installed on the top of the mounting groove 2. The drive shaft at the bottom of the drive motor 21 is fixedly connected to the lead screw 22. The bottom end of the lead screw 22 is rotatably connected to the bottom of the mounting groove 2. The screw block 23 is threadedly connected to the outside of the lead screw 22. The moving block 24 is fixedly connected to the front side of the screw block 23. A T-slot 25 is opened on the front side of the moving block 24. A limit plate 26 is fixedly connected to the front side of the frame 13. Placement grooves 27 are opened on the front side of the limit plate 26 and the front side of the bottom of the frame 13.

[0032] During sampling, the sampling syringe 14 is placed in the placement groove 27, and the piston rod of the sampling syringe 14 is placed in the T-shaped groove 25. Then, the needle of the sampling syringe 14 is inserted into the sample container. Subsequently, the drive motor 21 is started to drive the lead screw 22 to rotate. When the lead screw 22 rotates, it engages with the screw block 23, thereby driving the screw block 23 to move along the inside of the mounting groove 2. The screw block 23 drives the moving block 24 to move upward, and the moving block 24 drives the piston rod to move upward, thereby extracting the sample from the sample container into the sampling syringe 14 to complete the sampling. The sample is then transferred to the reagent bottle. Compared with manual sampling, this method is more stable and avoids leakage caused by vibration and collision during the transfer, which helps to improve the stability of the operation. In addition, the sampling syringe 14 can be easily replaced. When replacing it, the sampling syringe 14 can be directly taken out from the placement groove 27 and then placed into a new sampling syringe 14 for sampling.

[0033] In a preferred embodiment, two spring plates 28 are fixedly connected to the bottom of the frame 13, and pipe clamps 29 are fixedly connected to the bottom ends of the two spring plates 28.

[0034] Furthermore, when installing the sampling syringe 14, the sampling syringe 14 is placed between the two tube clamps 29, and the sampling syringe 14 is held in place by the elastic force of the two spring plates 28 to prevent the sampling syringe 14 from easily loosening.

[0035] Example 3

[0036] Based on Embodiment 1, the solution in Embodiment 1 will be further described in detail below with reference to the specific working method, such as... Figures 1 to 5 As shown below, see details:

[0037] A mounting plate 3 is provided between the two opposite sides of the gantry frame 11. A multi-axis linear guide rail 31 is fixedly installed at the bottom of the mounting plate 3. An electric push rod 32 is fixedly installed at the top of the gantry frame 11. The output end of the electric push rod 32 at the bottom is connected to the top of the mounting plate 3. The frame 13 is fixedly installed on the multi-axis guide rail 31. Two sliding grooves 33 are respectively opened on the two opposite sides of the gantry frame 11. A guide rod 34 is fixedly connected between the top and bottom of the sliding groove 33. A slider 35 is slidably connected to the outside of the guide rod 34. The sliders 35 on both sides are respectively connected to the opposite ends of the mounting plate 3.

[0038] Specifically: When the sampling syringe 14 is inserted into the container holding the product, the frame 13 can move laterally and vertically via the multi-axis linear guide rail 31, so that the sampling syringe 14 can be aligned with the container. The medium-activated electric push rod 32 pushes the mounting plate 3 downward, causing the sliders 35 at both ends of the mounting plate 3 to move along the outside of the guide rod 34, so that the mounting plate 3 moves smoothly up and down. The mounting plate 3 drives the multi-axis linear guide rail 31 to rise and fall, so that the sampling syringe 14 is inserted into the container holding the product for sampling. After sampling is completed, the electric push rod 32 is controlled to retract and move upward, so that the sampling syringe 14 is removed from the container holding the product. Then, the sampling syringe 14 is inserted into the sample bottle, so that the collected sample is pushed out and transferred to the sample bottle.

[0039] All electrical components mentioned in the text are electrically connected to the main controller and power supply. The main controller can be a conventional and known device such as a computer, and the existing publicly available power connection technology will not be elaborated in the text.

[0040] The above description is merely a preferred embodiment of this application and is not intended to limit this application. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of this application should be included within the protection scope of this application.

Claims

1. A sampling device for biological product research and development, characterized in that, include: Cabinet (1), a gantry frame (11) is fixedly installed on the top of the cabinet (1), a placement board (12) is fixedly installed on the top of the cabinet (1), a frame (13) is provided on the placement board (12), and a sampling syringe (14) is provided inside the frame (13); The sampling mechanism is located on the frame (13) and is used to sample the sample. The sampling mechanism includes: mounting groove (2), drive motor (21), lead screw (22), screw block (23), moving block (24) and T-slot (25).

2. The sampling device for biological product research and development according to claim 1, characterized in that, The frame (13) has a mounting groove (2) fixedly installed inside. A drive motor (21) is fixedly installed on the top of the mounting groove (2). A lead screw (22) is fixedly connected to the drive shaft at the bottom of the drive motor (21). The bottom end of the lead screw (22) is rotatably connected to the bottom of the mounting groove (2). A screw block (23) is threadedly connected to the outside of the lead screw (22). A moving block (24) is fixedly connected to the front side of the screw block (23). A T-shaped groove (25) is opened on the front side of the moving block (24).

3. The sampling device for biological product research and development according to claim 1, characterized in that, The gantry frame (11) is provided with an installation plate (3) between its two opposite sides. A multi-axis linear guide rail (31) is fixedly installed at the bottom of the installation plate (3). An electric push rod (32) is fixedly installed at the top of the gantry frame (11). The output end of the electric push rod (32) at the bottom is connected to the top of the installation plate (3). The frame (13) is fixedly installed on the multi-axis linear guide rail (31).

4. The sampling device for biological product research and development according to claim 1, characterized in that, A limiting plate (26) is fixedly connected to the front side of the frame (13), and a placement groove (27) is provided on the front side of the limiting plate (26) and the front side of the bottom of the frame (13).

5. The sampling device for biological product research and development according to claim 1, characterized in that, Two spring plates (28) are fixedly connected to the bottom of each frame (13), and pipe clamps (29) are fixedly connected to the bottom ends of the two spring plates (28).

6. The sampling device for biological product research and development according to claim 3, characterized in that, The gantry (11) has two sliding grooves (33) on opposite sides. A guide rod (34) is fixedly connected between the top and bottom of the sliding groove (33). A slider (35) is slidably connected to the outside of the guide rod (34). The sliders (35) on both sides are connected to the opposite ends of the mounting plate (3).

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