An in-situ intracranial tumor model construction operation platform with anesthesia and warming functions

Abstract

The utility model relates to an intracranial in situ tumor model construction operation platform with anesthesia and heat preservation functions, belongs to the biomedical experiment equipment technical field, including operation platform, the placement groove of opening in operation platform inside and the anesthesia face guard of fixed mounting in operation platform top one side, the upper surface of operation platform is provided with quantitative delivery mechanism, and the bottom of operation platform is provided with adjusting assembly. This intracranial in situ tumor model construction operation platform with anesthesia and heat preservation functions, through the controller starts the motor work, drive rotary disc and crank operation drive piston rod reciprocating motion in the installation cylinder, through the liquid outlet pipe and hose delivery to anesthesia face guard, ensure that the mouse maintains stable anesthesia state in the operation process, can realize the continuous, accurate delivery of anesthetics, reduces the waste of anesthetics, and simultaneously can adjust the delivery dose and speed of anesthetics according to different experimental requirements, reaches the advantage that the experiment accuracy is high.

Description

Technical Field

[0001] This utility model relates to the field of biomedical experimental equipment technology, specifically to an operational platform for constructing an intracranial in situ tumor model with anesthesia and heat preservation functions. Background Technology

[0002] Animal experiments refer to scientific research conducted in a laboratory using animals to gain new knowledge or solve specific problems in fields such as biology and medicine. Animal experiments must be conducted by trained personnel with research degrees or professional technical skills, or under their guidance. In animal experiments using mice as subjects, surgery is often required to obtain more effective data.

[0003] In biomedical experiments, a platform for constructing intracranial in situ tumor models with anesthesia and warming functions is required. Existing platforms have shortcomings in anesthetic drug delivery, mouse warming, and ease of surgical operation. Furthermore, current anesthesia methods often struggle to precisely control anesthetic dosage, leading to inconsistent depths of anesthesia and affecting the accuracy of experimental results. Simultaneously, a drop in mouse body temperature during surgery can impact their physiological state and experimental results, failing to meet experimental requirements. Therefore, this paper proposes a platform for constructing intracranial in situ tumor models with anesthesia and warming functions to address the aforementioned problems. Utility Model Content

[0004] To address the shortcomings of existing technologies, this invention provides an operational platform for constructing an intracranial in situ tumor model with anesthesia and warming functions. It boasts advantages such as high experimental accuracy and strong practicality, solving the deficiencies of existing platforms in anesthetic drug delivery, mouse warming, and ease of surgical operation. Furthermore, current anesthesia methods often struggle to precisely control anesthetic drug dosage, leading to inconsistent depths of anesthesia in mice and affecting the accuracy of experimental results. Additionally, the drop in mouse body temperature during surgery can impact their physiological state and experimental results, failing to meet experimental requirements.

[0005] To achieve the above objectives, the present invention provides the following technical solution: an intracranial in situ tumor model construction operation platform with anesthesia and heat preservation functions, including an operation table, a placement slot opened inside the operation table, and an anesthesia mask fixedly installed on one side of the top of the operation table. The upper surface of the operation table is provided with a quantitative delivery mechanism, and the bottom of the operation table is provided with an adjustment component.

[0006] The quantitative delivery mechanism includes an anesthetic drug storage tank fixedly installed on the top of the operating table, an installation cylinder fixedly connected to one side of the top of the operating table, a piston rod slidably connected inside the installation cylinder, an inlet pipe fixedly connected to the right side of the installation cylinder, an outlet pipe fixedly connected to the left side of the installation cylinder, and a drive mechanism set on the upper surface of the operating table.

[0007] The adjustment assembly includes a threaded sleeve fixedly connected to the bottom of the operating table, a screw threadedly connected inside the threaded sleeve, and a support plate fixedly connected to the bottom end of the screw.

[0008] Furthermore, the drive mechanism includes a mounting base fixedly connected to the top of the operating table, a motor fixedly mounted outside the mounting base, a rotating disk fixedly connected to the output shaft of the motor, and a crank hinged to the outside of the rotating disk.

[0009] Furthermore, the piston rod is slidably connected to the inside of the mounting cylinder and extends to its outside, with the end of the piston rod away from the mounting cylinder being hinged to the crank.

[0010] Furthermore, an extraction tube is fixedly connected between the inlet pipe and the anesthetic drug storage tank, and a flexible tube is fixedly connected between the outlet pipe and the anesthetic mask.

[0011] Furthermore, valve plates are rotatably installed inside both the inlet pipe and the outlet pipe, and the two valve plates are hinged to each other.

[0012] Furthermore, the anesthetic storage tank is a hollow cylinder, and a drug addition port is fixedly connected to the upper surface of the anesthetic storage tank.

[0013] Furthermore, the number of adjustment components is four sets, and the four sets of adjustment components are distributed at equal intervals at the bottom of the operating table.

[0014] Furthermore, a graphene film is fixedly installed inside the placement groove, and an injection needle is detachably installed on the upper surface of the operating table, with one end of the injection needle fixedly connected to an infusion tube.

[0015] Furthermore, the upper surface of the operating table is provided with a fixing component, which includes a fixing seat fixedly connected to the top of the operating table, a threaded rod rotatably connected inside the fixing seat, a clamping seat provided at one end of the threaded rod, and a knob fixedly connected to the other end of the threaded rod.

[0016] Furthermore, the number of fixing components is four sets, and the four sets of fixing components are distributed at equal intervals on the upper surface of the operating table.

[0017] Compared with the prior art, this utility model provides an operational platform for constructing an intracranial in situ tumor model with anesthesia and heat preservation functions, which has the following beneficial effects:

[0018] 1. This intracranial in situ tumor model construction platform, which has anesthesia and warming functions, starts the motor through the controller, drives the rotating disk and crank to rotate, and drives the piston rod to reciprocate in the mounting cylinder. The anesthetic is drawn from the storage tank through the inlet pipe and delivered to the anesthesia mask through the outlet pipe and hose, ensuring that the mice maintain a stable anesthesia state during the operation. It can achieve continuous and precise delivery of anesthetic, reduce the waste of anesthetic, and adjust the delivery dosage and speed of anesthetic according to different experimental needs, thus achieving the advantage of high experimental accuracy.

[0019] 2. This intracranial in situ tumor model construction platform, which features anesthesia and thermal insulation functions, uses fixation components for multi-point fixation and precise clamping, keeping mice stable during surgery and reducing stress responses caused by struggling or movement. This makes the surgical procedure smoother and reduces surgical interruptions caused by animal movement. Furthermore, the thermal conductivity of the graphene film, combined with the precise drug delivery function of the injection needle and infusion tubing, provides an optimized experimental environment for constructing a mouse intracranial in situ tumor model, achieving the advantage of strong practicality. Attached Figure Description

[0020] Figure 1 This is a three-dimensional view of the structure of this utility model;

[0021] Figure 2 This is a three-dimensional cross-sectional view of the quantitative conveying mechanism of this utility model;

[0022] Figure 3 This utility model Figure 1 A magnified structural diagram of structure A is shown.

[0023] In the diagram: 1. Operating table; 2. Placement slot; 3. Anesthesia mask; 4. Quantitative delivery mechanism; 41. Anesthetic drug storage tank; 42. Mounting cylinder; 43. Piston rod; 44. Inlet pipe; 45. Outlet pipe; 46. Tube; 47. Extraction pipe; 48. Mounting base; 49. Motor; 410. Rotary disc; 411. Crank; 412. Drug injection port; 5. Adjustment component; 51. Threaded sleeve; 52. Screw; 53. Support plate; 6. Graphene film; 7. Injection needle; 8. Fixing component; 81. Fixing base; 82. Threaded rod; 83. Clamping base; 84. Knob. Detailed Implementation

[0024] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0025] Please see Figures 1 to 3 An intracranial in situ tumor model construction operation platform with anesthesia and heat preservation functions in this embodiment includes an operation table 1, a placement slot 2 opened inside the operation table 1, and an anesthesia mask 3 fixedly installed on one side of the top of the operation table 1. A quantitative delivery mechanism 4 is provided on the upper surface of the operation table 1, and an adjustment component 5 is provided on the bottom of the operation table 1.

[0026] The quantitative delivery mechanism 4 includes an anesthetic storage tank 41 fixedly installed on the top of the operating table 1, an installation cylinder 42 fixedly connected to one side of the top of the operating table 1, a piston rod 43 slidably connected inside the installation cylinder 42, an inlet pipe 44 fixedly connected to the right side of the installation cylinder 42, an outlet pipe 45 fixedly connected to the left side of the installation cylinder 42, and a drive mechanism disposed on the upper surface of the operating table 1.

[0027] Specifically, the drive mechanism includes a mounting base 48 fixedly connected to the top of the control panel 1, a motor 49 fixedly mounted outside the mounting base 48, a rotating disk 410 fixedly connected to the output shaft of the motor 49, and a crank 411 hinged to the outside of the rotating disk 410.

[0028] It should be noted that the piston rod 43 is slidably connected to the inside of the mounting cylinder 42 and extends to its outside. The end of the piston rod 43 away from the mounting cylinder 42 is hinged to the crank 411. An extraction tube 47 is fixedly connected between the inlet pipe 44 and the anesthetic storage tank 41, and a flexible tube 46 is fixedly connected between the outlet pipe 45 and the anesthesia mask 3. Valve plates are rotatably installed inside both the inlet pipe 44 and the outlet pipe 45, and the two valve plates are hinged relative to each other. The motor 49 is started by the controller, driving the rotating disk 410 and the crank 411 to rotate, causing the piston rod 43 to reciprocate within the mounting cylinder 42. The anesthetic is drawn from the storage tank 41 through the inlet pipe 44 and delivered to the anesthesia mask 3 via the outlet pipe 45 and the flexible tube 46, ensuring that the mouse maintains a stable anesthesia state during surgery and enabling continuous and precise delivery of the anesthetic.

[0029] In addition, the anesthetic storage tank 41 is a hollow cylinder, and the upper surface of the anesthetic storage tank 41 is fixedly connected to the drug injection port 412.

[0030] In this embodiment, the adjustment assembly 5 includes a threaded sleeve 51 fixedly connected to the bottom of the operating table 1, a screw 52 threadedly connected inside the threaded sleeve 51, and a support plate 53 fixedly connected to the bottom end of the screw 52. There are four sets of adjustment assemblies 5, which are distributed at equal intervals at the bottom of the operating table 1.

[0031] In this embodiment, a graphene film 6 is fixedly installed inside the placement groove 2, and an injection needle 7 is detachably installed on the upper surface of the operating table 1. One end of the injection needle 7 is fixedly connected to an infusion tube.

[0032] In this embodiment, a fixing component 8 is provided on the upper surface of the operating table 1. The fixing component 8 includes a fixing seat 81 fixedly connected to the top of the operating table 1, a threaded rod 82 rotatably connected inside the fixing seat 81, a clamping seat 83 provided at one end of the threaded rod 82, and a knob 84 fixedly connected to the other end of the threaded rod 82. There are four sets of fixing components 8, which are distributed at equal intervals on the upper surface of the operating table 1.

[0033] The working principle of the above embodiments is as follows:

[0034] In practical applications, mice are placed on the operating table 1 and precisely held in place by the fixing components 8 at multiple points, keeping the mice stable during surgery and reducing stress responses caused by struggling or moving. The controller starts the motor 49, which drives the rotating disk 410 and crank 411 to rotate, causing the piston rod 43 to reciprocate within the mounting cylinder 42. The anesthetic is drawn from the anesthetic storage tank 41 through the inlet pipe 44 and delivered to the anesthesia mask 3 through the outlet pipe 45 and the tubing 46, ensuring that the mice maintain a stable state of anesthesia during surgery and enabling continuous and precise delivery of anesthetic. This operating table 1 can efficiently and safely construct mouse intracranial in situ tumor models, providing a reliable experimental tool for biomedical research.

[0035] The installation, connection, or setting methods disclosed in this embodiment are all common mechanical connection methods. Any method that can achieve its beneficial effect can be implemented. In addition, the electrical components in this embodiment are all electrically connected to the main controller and the power supply. The main controller can be a conventional known device such as a computer that plays a control role. Those skilled in the art can control the electrical components through simple programming. Moreover, the existing disclosed power connection technology is also common knowledge in the field. Therefore, the specific structural composition and working principle will not be described in detail in this embodiment.

[0036] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitations, an element defined by the phrase "comprising one..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes said element.

[0037] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A platform for constructing an intracranial in situ tumor model with anesthesia and warming functions, characterized in that: It includes an operating table (1), a placement slot (2) inside the operating table (1), and an anesthesia mask (3) fixedly installed on one side of the top of the operating table (1). The upper surface of the operating table (1) is provided with a quantitative delivery mechanism (4), and the bottom of the operating table (1) is provided with an adjustment component (5). The quantitative delivery mechanism (4) includes an anesthetic drug storage tank (41) fixedly installed on the top of the operating table (1), an installation cylinder (42) fixedly connected to one side of the top of the operating table (1), a piston rod (43) slidably connected inside the installation cylinder (42), an inlet pipe (44) fixedly connected to the right side of the installation cylinder (42), an outlet pipe (45) fixedly connected to the left side of the installation cylinder (42), and a drive mechanism set on the upper surface of the operating table (1). The adjustment assembly (5) includes a threaded sleeve (51) fixedly connected to the bottom of the operating table (1), a screw (52) threadedly connected to the inside of the threaded sleeve (51), and a support plate (53) fixedly connected to the bottom of the screw (52). The drive mechanism includes a mounting base (48) fixedly connected to the top of the operating table (1), a motor (49) fixedly mounted outside the mounting base (48), a rotating disk (410) fixedly connected to the output shaft of the motor (49), and a crank (411) hinged to the outside of the rotating disk (410).

2. The intracranial in situ tumor model construction operation platform with anesthesia and heat preservation functions according to claim 1, characterized in that: The piston rod (43) is slidably connected to the inside of the mounting cylinder (42) and extends to its outside. The end of the piston rod (43) away from the mounting cylinder (42) is hinged to the crank (411).

3. The intracranial in situ tumor model construction operation platform with anesthesia and heat preservation functions according to claim 1, characterized in that: The inlet pipe (44) is fixedly connected to the anesthetic drug storage tank (41) by an extraction pipe (47), and the outlet pipe (45) is fixedly connected to the anesthetic mask (3) by a flexible tube (46).

4. The intracranial in situ tumor model construction operation platform with anesthesia and heat preservation functions according to claim 1, characterized in that: Both the inlet pipe (44) and the outlet pipe (45) are rotatably mounted with valve plates inside, and the two valve plates are hinged to each other.

5. The intracranial in situ tumor model construction operation platform with anesthesia and heat preservation functions according to claim 1, characterized in that: The anesthetic storage tank (41) is a hollow cylinder, and the upper surface of the anesthetic storage tank (41) is fixedly connected to the drug inlet (412).

6. The intracranial in situ tumor model construction operation platform with anesthesia and heat preservation functions according to claim 1, characterized in that: The number of adjustment components (5) is four sets, and the four sets of adjustment components (5) are distributed at equal intervals at the bottom of the operating table (1).

7. The intracranial in situ tumor model construction operation platform with anesthesia and heat preservation functions according to claim 1, characterized in that: A graphene film (6) is fixedly installed inside the placement groove (2), and an injection needle (7) is detachably installed on the upper surface of the operating table (1). One end of the injection needle (7) is fixedly connected to an infusion tube.

8. The intracranial in situ tumor model construction operation platform with anesthesia and heat preservation functions according to claim 1, characterized in that: The upper surface of the operating table (1) is provided with a fixing component (8), which includes a fixing seat (81) fixedly connected to the top of the operating table (1), a threaded rod (82) rotatably connected inside the fixing seat (81), a clamping seat (83) provided at one end of the threaded rod (82), and a knob (84) fixedly connected to the other end of the threaded rod (82).

9. The intracranial in situ tumor model construction operation platform with anesthesia and heat preservation functions according to claim 8, characterized in that: The number of the fixing components (8) is four sets, and the four sets of fixing components (8) are distributed at equal intervals on the upper surface of the operating table (1).

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