Audiovisual organ integration device

Abstract

The utility model relates to animal pathological experiment technical field, more particularly to audio-visual organ integration sampling device, include: sampling board, the sampling board constructs for the light -transmitting structure, the bottom of sampling board is equipped with the polychromatic light source for the illumination sampling board, make the tissue structure that is in the sampling board work surface can be in different color light source background, the work surface of sampling board includes sampling area and waste recovery area. The utility model integrates multiple function design, including adopting polychromatic light source to create polychromatic backlight environment for sampling board, set up the positioning groove of spherical / ellipsoidal surface and the linear positioning groove of grid on the surface of sampling board, are used for positioning the cutting direction of special tissue and cutter, are favorable to the formation even thickness's tissue section, in addition, through the cross laser projection, magnifying glass and auxiliary lighting device that set up, are favorable to the improvement sampling precision, increase the observation definition of small structure.

Description

Technical Field

[0001] This utility model relates to the field of animal pathology experimental technology, and more specifically to an integrated sampling device for visual and auditory organs. Background Technology

[0002] In toxicological pathology studies, the assessment of the visual, auditory, and neurological systems is a core area of ​​special sensory and neurotoxicology. These studies aim to systematically evaluate whether test substances cause damage to these highly sensitive and functionally critical systems.

[0003] Toxicity studies of the visual system require meticulous sampling and processing of the eyeball, including corneal / iris fenestration, macular region localization, and optic nerve directional slicing. Toxicity studies of the auditory system require procedures such as ossicle separation and cochlear / vestibular localization sampling. Toxicity studies of neurotransmission require procedures such as ganglion or brain sampling.

[0004] It should be understood that during the above-mentioned material collection process, different difficulties may be encountered in the delicate operation due to the different structural characteristics of various tissues. For example, the cochlear tissue is small in size and located in the ear canal, requiring close-range light source for delicate dissection. For example, the eyeball is round and filled with vitreous fluid, making it difficult to apply uniform vertical force during material collection, and it is easy to deviate from the intended position. For example, the brain of large animals is large and difficult to position vertically, resulting in uneven thickness. In addition, there is a risk of cross-contamination due to the accumulation of tissue debris on the workbench.

[0005] Therefore, there is an urgent need for an integrated and intelligent material extraction device to address the above problems. Utility Model Content

[0006] To address the technical problems existing in the material-collecting workbench of the prior art, this utility model proposes an integrated material-collecting device for audiovisual organs, comprising:

[0007] The material sourcing board is constructed as a light-transmitting structure, and the bottom of the material sourcing board is provided with a multi-color light source for illuminating the material sourcing board, so that the tissue structure on the working surface of the material sourcing board can be in the background of different colored light sources. The working surface of the material sourcing board includes a material sourcing area and a waste recycling area.

[0008] A waste collection component is located below the material extraction plate and corresponding to the waste recycling area, for collecting waste transferred from the material extraction area to the waste recycling area;

[0009] An auxiliary positioning component is connected to the sampling plate and can project a crosshair mark onto the target position of the sampling area of ​​the sampling plate.

[0010] An auxiliary observation component, connected to the sampling plate, is configured to optically magnify the target tissue structure located in the sampling area on the sampling plate;

[0011] An auxiliary lighting component, connected to the sampling plate, is configured to provide supplemental lighting for the target tissue structure located in the sampling area on the sampling plate.

[0012] The sampling plate has several positioning grooves with spherical / ellipsoidal curved surfaces on its working surface in the sampling area for positioning spherical target tissue structures. The sampling plate also has linear positioning grooves that fill the sampling area and are distributed in a grid pattern on its working surface, so that the tool can slice the target tissue structure along the extension direction of the linear positioning grooves.

[0013] Preferably, the material board comprises a white acrylic board.

[0014] Preferably, the spacing between the plurality of linear positioning grooves arranged in parallel along the first direction is A, and the spacing between the plurality of linear positioning grooves arranged in parallel along the second direction is B, wherein A≥B.

[0015] Preferably, the linear positioning groove is configured to extend downwards to a predetermined depth along the surface of the working surface of the sampling plate.

[0016] Preferably, the working surface of the material sampling plate is provided with multiple positioning grooves of different sizes and depths of spherical / ellipsoidal curved surfaces located within the material sampling area.

[0017] Preferably, the auxiliary positioning component includes a first optical positioning component and a second optical positioning component. The first optical positioning component can move along a first direction, and the second optical positioning component can move along a second direction. The first optical positioning component can emit a planar beam along the second direction, and the second optical positioning component can emit a planar beam along the first direction. The first optical positioning component and the second optical positioning component together form a cross mark line in the sampling area.

[0018] Preferably, both the auxiliary observation component and the auxiliary lighting component are connected to the sampling plate via a multi-degree-of-freedom connecting arm.

[0019] Preferably, the multi-degree-of-freedom connecting arm includes a gooseneck tube or a cantilevered multi-angle adjustment component.

[0020] Preferably, the depth of the linear positioning groove is 0.5 to 1.0 mm, and the minimum distance between adjacent linear positioning grooves is 3 mm.

[0021] Preferably, the center point of the positioning groove is located at the intersection of the linear positioning grooves.

[0022] Compared with the prior art, the advantages of this utility model are:

[0023] This utility model integrates multiple functional designs, including using multi-color light sources to create a multi-color backlight environment for the sampling plate, and setting spherical / ellipsoidal curved surface positioning grooves and grid-like linear positioning grooves on the surface of the sampling plate for positioning specific tissues and the cutting direction of the blade, which is conducive to forming tissue sections of uniform thickness; in addition, the setting of cross laser projection, magnifying glass and auxiliary lighting device helps to improve sampling accuracy and increase the clarity of observation of microstructures. At the same time, the design of waste recycling area and drawer supports rapid rinsing and cleaning, avoids cross-contamination, and can adapt to the sampling needs of different species of animals for eye, ear, nerve and testicular / tumor tissue. Attached Figure Description

[0024] The accompanying drawings are not intended to be drawn to scale. In the drawings, each identical or nearly identical component shown in the various figures may be denoted by the same reference numeral. For clarity, not every component is labeled in each figure. Embodiments of various aspects of the present invention will now be described by way of example and with reference to the accompanying drawings, wherein:

[0025] Figure 1 This is a schematic diagram of the integrated audiovisual organ sampling device shown in this utility model;

[0026] Figure 2 This is a top view of the integrated audiovisual organ sampling device shown in this utility model;

[0027] Figure 3 This is a side view of the integrated audiovisual organ sampling device shown in this utility model;

[0028] Figure 4 This is a schematic diagram of the linear positioning groove of this utility model being positioned in the positioning groove. Detailed Implementation

[0029] To better understand the technical content of this utility model, specific embodiments are provided below in conjunction with the accompanying drawings.

[0030] Combination Figures 1 to 3 As shown, this utility model proposes an integrated sampling device for visual and auditory organs, which is suitable for the separation operation of eye tissue, ear tissue, nerve tissue and other materials in different species of animals (such as dogs, monkeys, mice, rabbits, etc.), and is especially suitable for toxicological pathology research, visual system and auditory system fine sampling operation.

[0031] The workstation includes a material sampling board 10, a waste collection component 20, an auxiliary positioning component, an auxiliary observation component 40, and an auxiliary lighting component 50.

[0032] The sampling plate 10 is designed to support and position the tissue to be sampled / separated, and to provide a luminescent background for the tissue to be sampled / separated, so as to improve the clarity of the vascular / membrane structure of the tissue.

[0033] Specifically, the material board 10 is constructed as a light-transmitting structure, and can be made of white acrylic sheet, which is easy to clean and allows light to pass through.

[0034] Furthermore, the bottom of the sampling plate 10 is provided with a multi-color light source 15 for illuminating the sampling plate 10, so that the tissue structure on the working surface of the sampling plate 10 can be in the background of different colored light sources.

[0035] Among them, the multi-color light source 15 can form cool light / warm light / soft light modes, which can be adjusted as needed to avoid visual fatigue caused by long-term operation.

[0036] In an optional embodiment, the multicolor light source 15 is attached to the bottom of the sampling plate 10 by being encapsulated in an acrylic plate, and can provide a glare-free operating environment to the sampling plate 10 through diffuse reflection.

[0037] Furthermore, the working surface of the material extraction board 10 includes a material extraction area 101 and a waste recycling area 102.

[0038] Understandably, the upper surface of the material board 10 is the working surface.

[0039] Combination Figure 2 As shown, the working surface of the sampling plate 10 is provided with a number of positioning grooves 11 with spherical / ellipsoidal curved surfaces in the sampling area 101, which are used to position the spherical target tissue structure. The working surface of the sampling plate 10 is provided with linear positioning grooves 12 that fill the sampling area 101 and are distributed in a grid pattern, so that the tool can slice the target tissue structure along the extension direction of the linear positioning grooves 12.

[0040] Thus, the positioning groove 11 can be used to locate circular or elliptical tissue structures (such as eyeball tissue and testicular tissue for different animal species), increasing the accuracy of material extraction. At the same time, in conjunction with the linear positioning groove 12, the tool trajectory is made to follow an accurate linear direction during material extraction, resulting in slices of uniform thickness.

[0041] Optionally, the working surface of the material sampling plate 10 is provided with multiple positioning grooves 11 of different sizes and depths of spherical / ellipsoidal curved surfaces located within the material sampling area 101.

[0042] Combination Figure 2 As shown, positioning grooves 11 of ellipsoidal curved surfaces of three or more sizes (diameters ranging from 1cm to 3cm) can be provided, as well as positioning grooves 11 of spherical curved surfaces of three or more sizes (diameters ranging from 1cm to 3cm).

[0043] This allows for the separation of tissues from different animal species.

[0044] like Figure 4 As shown, in a preferred embodiment, the center point of the positioning groove 11 is located at the intersection of the linear positioning grooves 12. Thus, when a circular or elliptical tissue structure is in the positioning groove 11, the cutting tool can start extracting material from the middle of the tissue structure along the linear positioning grooves 12.

[0045] In an optional embodiment, the spacing between the plurality of linear positioning grooves 12 arranged in parallel along the first direction is A, and the spacing between the plurality of linear positioning grooves 12 arranged in parallel along the second direction is B, wherein A≥B.

[0046] When A = B, the horizontally arranged linear positioning grooves 12 and the vertically arranged linear positioning grooves 12 are spaced at the same distance, forming a standard square grid pattern. This ensures that slices of the same thickness can be formed regardless of whether the cut is horizontal or vertical.

[0047] In other embodiments, the spacing between the transversely arranged linear positioning grooves 12 can be greater than the spacing between the longitudinally arranged linear positioning grooves 12, so that slices of different thicknesses can be obtained when taking materials transversely and longitudinally to meet different needs.

[0048] In the above embodiments, the depth of the linear positioning groove 12 is 0.5 to 1.0 mm to meet the positioning requirements of the tool.

[0049] In an optional embodiment, the linear positioning groove 12 is configured to extend downward to a predetermined depth along the surface of the working surface of the material taking plate 10.

[0050] In other words, regardless of whether the sampling plate 10 has a positioning groove 11 or not, a linear positioning groove 12 with a depth of 0.5 to 1.0 mm is provided, allowing the tool to move in a predetermined direction while passing through the positioning groove 11. Optionally, the minimum distance between adjacent linear positioning grooves 12 is 3 mm. Therefore, when the tool continuously samples tissue structures along the linear positioning grooves 12, a tissue section with a thickness of 3 mm can be formed.

[0051] Furthermore, by setting up a material extraction area 101 and a waste recycling area 102, it is convenient to quickly transfer the separated waste tissue to the waste recycling area 102. Specifically, after the current target tissue is cut and separated, the surface of the material extraction area 101 can be rinsed with water to wash the waste into the waste recycling area 102, where it is collected by the waste collection component 20 located below the material extraction plate 10 and corresponding to the position of the waste recycling area 102.

[0052] Optionally, a support plate 14 is provided below the material collection plate 10 so that the material collection plate 10 is positioned above the waste collection component 20.

[0053] Optionally, the waste collection component 20 is a stainless steel drawer structure. The drawer structure is designed to be pulled out from below the material collection plate 10. The drawer structure can be removed from the material collection plate 10 at any time according to the user's needs to facilitate emptying into the trash can.

[0054] In an optional embodiment, two waste collection components 20 are provided, and are respectively located on the left and right sides of the material collection plate 10.

[0055] Thus, this structural design facilitates the rapid cleaning of the sampling plate 10, for example, cleaning the work surface within 5 to 10 seconds, avoiding the risk of cross-contamination caused by the accumulation of tissue debris, and creating a clean environment for pathologists to read slides.

[0056] Furthermore, the auxiliary positioning component is connected to the sampling plate 10 and can project a crosshair line onto the target position of the sampling area 101 of the sampling plate 10.

[0057] The cross-shaped markings allow for the cross-positioning of tissues and organs, ensuring that the ear tissue is divided into two pieces to the greatest extent possible, facilitating pathological sections and slides from the same ear. Simultaneously, the sampling plate is covered with several crisscrossing, shallow grooves, which can be used for horizontal positioning of the blade during sampling.

[0058] Preferably, the line width of the cross mark is 0.1 mm.

[0059] This allows for high-precision positioning, which helps maintain the cutting tool's material-taking state and ensures that the material-taking plane is an ideal plane.

[0060] Optionally, the auxiliary positioning components include a first optical positioning component 31 and a second optical positioning component 32. The first optical positioning component 31 can move along a first direction, and the second optical positioning component 32 can move along a second direction. The first optical positioning component 31 can emit a planar beam along the second direction, and the second optical positioning component 32 can emit a planar beam along the first direction. The first optical positioning component 31 and the second optical positioning component 32 together form a cross mark line in the sampling area 101.

[0061] Specifically, both the first optical positioning component 31 and the second optical positioning component 32 are laser levels. The laser level can emit linear beams, and the intersection of two linear beams can form a cross-shaped marking line.

[0062] Specifically, a track 13 is provided above the material sampling plate 10, and the first optical positioning component 31 and the second optical positioning component 32 can move on the track 13, so that the first optical positioning component 31 can move along the first direction and the second optical positioning component 32 can move along the second direction.

[0063] Furthermore, in the above embodiments, if the tissue structure is small, it can be magnified and observed by the auxiliary observation component 40. The auxiliary observation component 40 is connected to the sampling plate 10 and is configured to optically magnify the target tissue structure on the sampling plate 10 located in the sampling area 101.

[0064] Specifically, the auxiliary observation component 40 is an adjustable magnifying glass equipped with a magnetic filter to enhance blood vessel contrast. This combination significantly improves the clarity of small tissue details.

[0065] Furthermore, in order to reduce shadow interference and provide stronger illumination, the auxiliary lighting component 50 may be a ring light connected to the sampling plate 10 and configured to provide supplemental lighting to the target tissue structure on the sampling plate 10 located in the sampling area 101.

[0066] The combination of a magnifying glass and a supplemental light significantly improves the clarity of fine tissue details, providing pathologists with clearer and more accurate observation conditions.

[0067] In the above embodiments, both the auxiliary observation component 40 and the auxiliary lighting component 50 are connected to the sampling plate 10 via a multi-degree-of-freedom connecting arm. The multi-degree-of-freedom connecting arm can be a gooseneck tube or a cantilevered multi-angle adjustment component to meet the requirement of multi-angle free adjustment of the auxiliary observation component 40 and the auxiliary lighting component 50.

[0068] In a specific embodiment for otology project sampling, a movable laser level is used to position the ear tissue on the sampling plate in a "cross" pattern. That is, the first optical positioning component 31 and the second optical positioning component 32 are moved to form a cross mark line to the target position. At the same time, the auxiliary lighting component 50 is turned on or off depending on the lighting conditions.

[0069] When the blade is cutting, it extends into the linear positioning groove 12, so that the cutting is in a straight line. After cutting, the cochlea, ossicles, semicircular canals and other tiny structures can be observed through the magnification of the auxiliary observation component 40.

[0070] In a specific embodiment for ophthalmic project sampling, the eyeball is placed in a suitable positioning groove 11 and fixed in position according to the size of the eyeball of different species. When the blade is cutting, it extends into the linear positioning groove 12 so that the cutting is in a straight line. Under the magnification of the auxiliary observation component 40, small structures such as the macula and retinal vascular arch can be observed.

[0071] In a specific embodiment for scavenging circular special project tissues, such as testes / tumors, the testes / tumors are placed in a suitable positioning groove 11 and fixed in position according to the size of the tissue. When the blade moves to cut, it is parallel to the linear positioning groove 12, and a uniform 3mm thick tissue sample can be obtained.

[0072] In the above-mentioned division and positioning of irregular tissues, such as irregular or round tissues like the cochlea and eyeball, the laser crosshair is first aligned with the predetermined cutting point of the tissue during cutting. Then, the tissue is rotated / translated to make key anatomical landmarks (such as the top of the cochlea and the center of the optic disc) coincide with the laser line. Finally, the cut is made along the linear positioning groove 12 to ensure that the cutting surface passes through the set mark, avoiding the slice deviation caused by traditional visual estimation.

[0073] Although the present invention has been disclosed above with reference to preferred embodiments, it is not intended to limit the present invention. Those skilled in the art to which this invention pertains can make various modifications and refinements without departing from the spirit and scope of the present invention. Therefore, the scope of protection of this invention shall be determined by the claims.

Claims

1. An integrated audiovisual organ sampling device, characterized in that, include: The material sampling board (10) is constructed to be light-transmitting. The bottom of the material sampling board (10) is provided with a multi-color light source (15) for illuminating the material sampling board (10), so that the tissue structure on the working surface of the material sampling board (10) can be in the background of different colored light sources. The working surface of the material sampling board (10) includes a material sampling area (101) and a waste recycling area (102). Waste collection component (20), located below the material extraction plate (10) and corresponding to the waste recycling area (102), is used to collect waste transferred from the material extraction area (101) to the waste recycling area (102); An auxiliary positioning component is connected to the sampling plate (10) and can project a cross mark line onto the target position of the sampling area (101) of the sampling plate (10); An auxiliary observation component (40), connected to the sampling plate (10), is configured to optically magnify the target tissue structure on the sampling plate (10) in the sampling area (101); An auxiliary lighting component (50), connected to the sampling plate (10), is configured to provide supplemental lighting for the target tissue structure on the sampling plate (10) in the sampling area (101); The working surface of the sampling plate (10) is provided with several positioning grooves (11) with spherical / ellipsoidal curved surfaces in the sampling area (101) for positioning the spherical target tissue structure. The working surface of the sampling plate (10) is provided with linear positioning grooves (12) that fill the sampling area (101) and are distributed in a grid pattern, so that the tool can slice the target tissue structure along the extension direction of the linear positioning grooves (12).

2. The integrated audiovisual organ sampling device according to claim 1, characterized in that, The material board (10) includes a white acrylic board.

3. The integrated audiovisual organ sampling device according to claim 1, characterized in that, The spacing between the multiple linear positioning grooves (12) arranged in parallel along the first direction is A, and the spacing between the multiple linear positioning grooves (12) arranged in parallel along the second direction is B, wherein A≥B.

4. The integrated audiovisual organ sampling device according to claim 1, characterized in that, The linear positioning groove (12) is configured to extend downward to a predetermined depth along the working surface of the material taking plate (10).

5. The integrated audiovisual organ sampling device according to claim 1, characterized in that, The working surface of the material sampling plate (10) is provided with multiple positioning grooves (11) of spherical / ellipsoidal curved surfaces of different sizes / depths located in the material sampling area (101).

6. The integrated audiovisual organ sampling device according to claim 1, characterized in that, The auxiliary positioning component includes a first optical positioning component (31) and a second optical positioning component (32). The first optical positioning component (31) can move along a first direction, and the second optical positioning component (32) can move along a second direction. The first optical positioning component (31) can emit a planar beam along the second direction, and the second optical positioning component (32) can emit a planar beam along the first direction. The first optical positioning component (31) and the second optical positioning component (32) together form a cross mark line in the sampling area (101).

7. The integrated audiovisual organ sampling device according to claim 1, characterized in that, The auxiliary observation component (40) and the auxiliary lighting component (50) are both connected to the sampling plate (10) via a multi-degree-of-freedom connecting arm.

8. The integrated audiovisual organ sampling device according to claim 7, characterized in that, The multi-degree-of-freedom connecting arm includes a gooseneck tube or a cantilevered multi-angle adjustment component.

9. The integrated audiovisual organ sampling device according to any one of claims 1-8, characterized in that, The depth of the linear positioning groove (12) is 0.5 to 1.0 mm, and the minimum distance between adjacent linear positioning grooves (12) is 3 mm.

10. The integrated audiovisual organ sampling device according to any one of claims 1-8, characterized in that, The center point of the positioning groove (11) is located at the intersection of the linear positioning groove (12).

Images