Needle holder angle adjuster for micromanipulation

Abstract

The utility model provides a kind of needle holder angle regulator for micro-operation, belong to medical instrument technical field.The regulator includes needle holder and arc guide rail and guide slide, rack is provided on arc guide rail, rack is arranged along the circumferential edge of arc guide rail, guide slide is slidably arranged on arc guide rail along the circumferential of arc guide rail, guide slide has opposite first end face and second end face, needle holder is set on first end face, driving gear is provided on second end face, driving gear is engaged with rack, needle holder is set towards the center of arc guide rail, limit wheel is provided on second end face, the inner edge of arc guide rail is abutted with the outer edge of limit wheel.Using the utility model embodiment provides a kind of needle holder angle regulator for micro-operation, can solve the problem of lower operation efficiency caused by lower operation convenience in prior art.

Description

Technical Field

[0001] This utility model relates to the field of medical device technology, and in particular to a needle holder angle adjuster for microscopic manipulation. Background Technology

[0002] Micromanipulation is a technique that uses a micromanipulator under a high-powered inverted microscope to control the movement of a micromanipulation needle within the microscope's field of view for the manipulation of cells or early embryos. The micromanipulation needle is typically fixed to a needle holder for operation. The needle tip is bent at a specific angle; during use, the needle shank is inserted into the needle holder and secured. The device used to adjust the tilt angle of the micromanipulation needle tip is called the needle holder angle adjuster.

[0003] In the existing technology, when adjusting the angle of the needle holder, the needle holder is usually clamped and fixed on a rotator. When the rotator is rotated, the tilt angle of the needle holder can change, thereby causing the angle of the operating needle to change. However, since the operation is observed through a microscope, this method of rotating the angle may also cause the position of the needle tip to change.

[0004] In existing needle holder angle adjusters, when the angle of the operating needle is adjusted by rotating the needle holder, the position of the needle tip will also change significantly. This change will cause the needle tip to be lost when adjusted to the center of the field of view that can be observed through the eyepiece. If the needle tip needs to be found in the field of view, the operating needle needs to be moved up and down or left and right, which makes the operation inconvenient. Utility Model Content

[0005] This utility model provides a needle holder angle adjuster for microscopic manipulation, which solves the problem of low operational efficiency due to low ease of operation in the prior art. The technical solution is as follows: A needle holder angle adjuster for micromanipulation, used to clamp and fix the needle holder and adjust its angle, includes: an arc-shaped guide rail, a rack, a gear, and a guide slide. The rack is arranged on the arc-shaped guide rail along the extension direction of the arc-shaped guide rail. The guide slide is slidably arranged on the arc-shaped guide rail along the circumference of the arc-shaped guide rail. The needle holder and the gear are arranged on the guide slide. The needle holder is arranged facing the center of the arc-shaped guide rail. The drive gear is arranged on one side of the arc-shaped guide rail and meshes with the rack. A limit wheel is arranged on the other side of the arc-shaped guide rail.

[0006] Optionally, two limit wheels are arranged at intervals, and a damping adjusting nut is provided between the two limit wheels. The damping adjusting nut abuts against the arc edge of the arc-shaped guide rail.

[0007] Optionally, the guide slide has a first end face and a second end face, the needle holder is disposed on the first end face, the drive gear and the limiting wheel are disposed on the second end face, the rack is arranged along the outer edge of the arc-shaped guide rail, the outer edge of the limiting wheel abuts against the inner edge of the arc-shaped guide rail, the arc-shaped guide rail has a third end face and a fourth end face, the third end face abuts against the second end face, the rack is disposed on the fourth end face, a first limiting block is disposed on the second end face, and the first limiting block abuts against the outer edge of the arc-shaped guide rail.

[0008] Optionally, the rack protrudes from the fourth end face, and a second limiting block is provided on the first limiting block, with the second limiting block located above the rack.

[0009] Optionally, a first scale line is provided on the third end face, and a scale indicator window is provided on the guide slide, wherein a scale pointer matching the first scale line is provided in the scale indicator window.

[0010] Optionally, an angle adjustment knob is provided on the first end face, the angle adjustment knob rotates coaxially with the drive gear, and a locking knob is provided on one side of the angle adjustment knob.

[0011] Optionally, a clamping mechanism is provided on the first end face. The clamping mechanism includes a needle holder, a needle holder pressure block, and a fastening knob. The needle holder has a clamping groove arranged radially along the arc-shaped guide rail. The needle holder is disposed in the clamping groove. The needle holder pressure block is slidably disposed on the top of the needle holder, and the bottom of the needle holder pressure block abuts against the needle holder. The fastening knob is disposed on the top of the needle holder pressure block.

[0012] Optionally, the needle holder is provided with a second scale line and a needle holder limiting ring, the end of which abuts against one side of the needle holder seat.

[0013] Optionally, a radial adjustment mechanism is provided on the first end face. The radial adjustment mechanism includes a bearing seat, a lead screw, and a radial adjustment knob. The needle holder has an assembly hole arranged radially along the arc-shaped guide rail. The assembly hole is threaded. The bearing seat is fixed on the first end face. The lead screw passes through the bearing seat. One end of the lead screw is connected to the radial adjustment knob, and the other end is threaded to the assembly hole.

[0014] Optionally, a guide rail is provided on the first end face, the guide rail is arranged radially along the arc-shaped guide rail, and a slot matching the guide rail is provided at the bottom of the needle holder.

[0015] The beneficial effects of the technical solution provided by this utility model embodiment include at least the following: This utility model provides a needle holder angle adjuster for microscopic manipulation. By setting an arc-shaped guide rail and a guide slide, the guide slide can slide along the arc-shaped guide rail. The drive gear and rack provide driving force, while the limiting wheel provides guiding force. When the drive gear and rack mesh, the needle tip of the needle holder always faces the center of the arc-shaped guide rail. This makes the adjuster a centering angle adjustment device. While adjusting the angle of the needle holder, it keeps the distance the needle tip moves relatively small. When the needle tip is straight, it can even keep the needle tip position unchanged. This allows the operator to always capture the needle tip in the microscope's field of view without having to perform additional adjustments due to changes in the needle tip's position, saving operation time. It can effectively solve the problem of low operation convenience and resulting in low operation efficiency in the prior art. Attached Figure Description

[0016] To more clearly illustrate the technical solutions in the embodiments of this utility model, the drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0017] Figure 1 This is a schematic diagram of the overall structure provided in an embodiment of the present utility model; Figure 2 This is a front structural diagram provided by an embodiment of the present utility model; Figure 3 This is a schematic diagram of the rear structure provided in an embodiment of the present invention; Figure 4 This is a schematic diagram of the needle holder holder structure provided in this embodiment of the utility model; Figure 5 This is a schematic diagram of the guide slide structure provided in an embodiment of the present utility model.

[0018] In the diagram: 1-Needle holder; 11-Second scale line; 12-Needle holder limiting ring; 2-Arc-shaped guide rail; 21-Third end face; 211-First scale line; 22-Fourth end face; 3-Rack; 4-Drive gear; 5-Guide slide; 51-First end face; 511-Angle adjustment knob; 512-Locking knob; 513-Guide rail; 52-Second end face; 521-Limiting wheel; 522-Damping adjustment nut; 523-First limiting block; 524-Second limiting block; 53-Scale indicator window; 531-Scale pointer; 6-Clamping mechanism; 61-Needle holder holder; 611-Clamping groove; 612-Assembly hole; 62-Needle holder pressure block; 63-Fasting knob; 64-Slot; 7-Radial adjustment mechanism; 71-Bearing seat; 72-Lead screw; 73-Radial adjustment knob; Detailed Implementation To make the objectives, technical solutions, and advantages of this utility model clearer, the embodiments of this utility model will be described in further detail below with reference to the accompanying drawings.

[0019] Figure 1 This is a schematic diagram of the overall structure provided in an embodiment of the present utility model; Figure 2 This is a front structural diagram provided by an embodiment of the present utility model; Figure 3 This is a schematic diagram of the rear structure provided in an embodiment of the present invention; Figure 4 This is a schematic diagram of the needle holder holder structure provided in this embodiment of the utility model; Figure 5 This is a schematic diagram of the guide slide structure provided in an embodiment of this utility model. Figures 1 to 5 The diagram shows a needle holder angle adjuster for microsurgery, used to clamp and fix the needle holder 1 and adjust its angle. It includes: an arc-shaped guide rail 2, a rack 3, a gear 4, and a guide slide 5. The rack 3 is arranged on the arc-shaped guide rail along its extension direction. The guide slide 5 is slidably arranged on the arc-shaped guide rail 2 along its circumference. The needle holder 1 and the gear 4 are arranged on the guide slide. The needle holder 1 is oriented towards the center of the arc-shaped guide rail 2. The drive gear 4 is arranged on one side of the arc-shaped guide rail 2 and meshes with the rack 3. A limit wheel 521 is arranged on the other side of the arc-shaped guide rail 2.

[0020] For example, in this embodiment of the invention, the regulator is mounted on the robotic arm of a microsurgical system for assisted reproduction, and is used to mount the needle holder 1. The glass needle held by the needle holder 1 is used to attract, grasp, or eject gametes (sperm, egg cells, etc.) through pressure, or the movement of the robotic arm is controlled by a joystick controller, while the needle tip moves to perform operations such as puncturing the egg cell. Angle limiting screws are provided at both ends of the arc-shaped guide rail 2 to prevent the guide slide 5 from derailing when moving on the arc-shaped guide rail 2. The rack 3 is arranged circumferentially along the arc-shaped guide rail 2, so the rack 3 is also an arc-shaped rack. The rack 3 is fixed on the arc-shaped guide rail 2. When the drive gear 4 meshes with the rack 3, it drives the guide slide 5 to move on the arc-shaped guide rail 2. The limiting wheel 521 abuts against the outer edge of the arc-shaped guide rail 2, thereby providing guiding force for the movement of the guide slide 5. The needle holder 1 is fixed on the guide slide 5, so that when the guide slide 5 moves along the arc-shaped guide rail 2, the end of the needle holder 1 always faces the center of the arc-shaped guide rail 2, so that the needle tip of the needle holder 1 is not lost in the field of view of the microscope eyepiece, which makes it convenient for the operator to find the needle tip and operate on the cells, thus improving the operation efficiency. Compared to traditional techniques where adjusting the angle of the needle holder 1 requires translation to bring the needle tip into the microscope's field of view, the adjuster in this embodiment can keep the needle tip's position essentially unchanged during the adjustment of the needle holder 1's angle. This makes it easier for the operator to find the needle tip in the microscope's field of view and continue subsequent operations, improving operational convenience and efficiency.

[0021] This utility model provides a needle holder angle adjuster for microscopic manipulation. By setting an arc-shaped guide rail 2 and a guide slide 5, the guide slide 5 can slide along the arc-shaped guide rail 2. The drive gear 4 and rack 3 provide driving force, while the limiting wheel 521 provides guiding force. When the drive gear and rack 3 mesh, the needle tip of the needle holder 1 always faces the center of the arc-shaped guide rail. This makes the adjuster a centering angle adjustment device, which keeps the distance the needle tip of the needle holder 1 moves small while adjusting the angle of the needle holder 1. Generally, the needle tip and the needle handle will form a certain angle. Even so, by adjusting the clamping position of the needle holder limiting ring 12 on the needle holder 1, the position of the needle tip can be kept within a relatively fixed small range or position in the microscope's field of view while the angle is adjusted. This prevents the needle tip from becoming out of focus, blurring, or losing the target object or the field of view of the needle tip. When the needle tip is straight, the position of the needle tip can even remain unchanged. This allows the operator to always capture the needle tip in the microscope's field of view without having to make additional adjustments due to changes in the position of the needle tip, saving operation time and effectively solving the problem of low operational convenience and low operational efficiency in existing technologies.

[0022] Optionally, two limit wheels 521 are arranged at intervals, and a damping adjusting nut 522 is provided between the two limit wheels 521. The damping adjusting nut 522 abuts against the arc edge of the arc-shaped guide rail 2.

[0023] Exemplary, in embodiments of this utility model, such as Figure 2 As shown, by setting two spaced-apart limit wheels 521, a more stable guiding force can be provided for the movement of the guide slide 5 on the arc-shaped guide rail 2, thereby making the sliding of the guide slide 5 smoother and improving the stability of this regulator. A damping adjustment nut 522 is set between the two limit wheels 521. By adjusting the tightening force, the damping of the guide slide 5 on the arc-shaped guide rail 2 can be adjusted, thereby adjusting the operating feel and further improving the ease of operation of this regulator.

[0024] Optionally, the guide slide 5 has a first end face 51 and a second end face 52 opposite to each other. The needle holder 1 is disposed on the first end face 51. The drive gear 4 and the limiting wheel 521 are disposed on the second end face 51. The rack 3 is arranged along the outer edge of the arc-shaped guide rail 2. The outer edge of the limiting wheel 521 abuts against the inner edge of the arc-shaped guide rail 2. The arc-shaped guide rail 2 has a third end face 21 and a fourth end face 22 opposite to each other. The third end face 21 abuts against the second end face 52. The rack 3 is disposed on the fourth end face 22. A first limiting block 523 is disposed on the second end face 52. The first limiting block 523 abuts against the outer edge of the arc-shaped guide rail 2.

[0025] Exemplary, in embodiments of this utility model, such as Figure 3 As shown, on the outer edge of the arc-shaped guide rail 2, not only is the drive gear 4 and the rack 3 engaged for positioning, but a first limiting block 523 is also provided to directly contact the outer edge of the arc-shaped guide rail 2, thereby achieving a precise radius arc guiding function and improving the accuracy of this regulator.

[0026] Optionally, the rack 3 protrudes from the fourth end face 22, and a second limit block 524 is provided on the first limit block 523, with the second limit block 524 located above the rack 3.

[0027] Exemplary, in embodiments of this utility model, such as Figure 3 As shown, by setting a second limiting block 524, the guide slide 5 can be effectively prevented from deviating in the non-guided direction. When the deviation is too large, the second limiting block 524 abuts against the rack 3 to prevent the guide slide 5 from disengaging from the arc-shaped guide rail 2, thereby further improving the stability of this regulator.

[0028] Optionally, a first scale line 211 is provided on the third end face 21, and a scale indicator window 53 is provided on the guide slide 5. A scale pointer 531 matching the first scale line 211 is provided in the scale indicator window 53.

[0029] Exemplary, in embodiments of this utility model, such as Figure 2As shown, when the guide slide 5 slides on the arc-shaped guide rail 2, the scale pointer 531 also slides on the first scale line 211. Thus, the distance that the guide slide 5 slides on the arc-shaped guide rail 2 can be accurately read from the first scale line 211, and the angle of rotation of the needle holder can be calculated accordingly. This allows the operator to make a fixed angle adjustment, further improving the ease of operation of this regulator.

[0030] Optionally, an angle adjustment knob 511 is provided on the first end face 51. The angle adjustment knob 511 rotates coaxially with the drive gear 4, and a locking knob 512 is provided on one side of the angle adjustment knob 511.

[0031] Exemplary, in embodiments of this utility model, such as Figure 2 and Figure 3 As shown, the angle adjustment knob 511 allows for convenient operation by the operator, enabling the drive gear 4 to move on the rack 3 and thus adjust the angle of the needle holder. The locking knob 512 secures the angle adjustment knob 511, thereby fixing the drive gear 4 and preventing relative movement between the drive gear 4 and rack 3 during cell manipulation, which could affect the operation. This design further improves the ease of operation of the regulator.

[0032] Optionally, a clamping mechanism 6 is provided on the first end face 51. The clamping mechanism 6 includes a needle holder 61, a needle holder pressure block 62, and a fastening knob 63. The needle holder 61 has a clamping groove 611 arranged radially along the arc-shaped guide rail 2. The needle holder 1 is disposed in the clamping groove 611. The needle holder pressure block 62 is slidably disposed on the top of the needle holder 61. The bottom of the needle holder pressure block 62 abuts against the needle holder 1. The fastening knob 63 is disposed on the top of the needle holder pressure block 62.

[0033] Exemplary, in embodiments of this utility model, such as Figure 2 and Figure 4 As shown, the clamping groove 611 has a V-shaped structure, which can be adapted to the cylindrical shell of the needle holder 1. The needle holder pressure block 62 is located on top of the needle holder base 61 and can slide horizontally, so that the bottom of the needle holder pressure block 62 abuts against the needle holder 1. During installation, first remove the needle holder pressure block 62 to expose the clamping groove 611. After placing the needle holder 1 on the clamping groove 611, slide the needle holder pressure block 62 to move it above the needle holder 1, so that the needle holder pressure block 62 and the clamping groove 611 clamp and fix the needle holder 1. Then rotate the fastening knob 63 to lock it and prevent the needle holder pressure block 62 from sliding again. By setting this structure, the operation is simple and the needle holder 1 can be quickly fixed or disassembled, further improving the ease of operation of this regulator.

[0034] Optionally, the needle holder 1 is provided with a second scale line 11 and a needle holder limiting ring 12, the end of which abuts against one side of the needle holder seat 61.

[0035] Exemplary, in embodiments of this utility model, such as Figure 2 As shown, the needle holder 1 may vary in length due to different manufacturers. To ensure that the needle tip is positioned appropriately when different sizes of needle holder 1 are installed on this adjuster, a second scale line 11 and a needle holder limiting ring 12 are provided on the needle holder 1. The limiting ring 12 is pre-calculated and aligned with the second scale line 11 before being fixed onto the needle holder 1. When the needle holder 1 is installed on the clamping groove 611, the limiting ring 12 abuts against the upper end of the needle holder holder 61, thus limiting the radial position of the needle holder 1 along the arc-shaped guide rail. This ensures that the needle tip is positioned appropriately after installation, facilitating quick needle tip location by the operator within the microscope's field of view. This structure not only improves the compatibility of the adjuster but also further enhances operational efficiency.

[0036] Optionally, a radial adjustment mechanism 7 is provided on the first end face 51. The radial adjustment mechanism 7 includes a bearing seat 71, a lead screw 72 and a radial adjustment knob 73. The needle holder 61 has an assembly hole 612 arranged radially along the arc-shaped guide rail 2. The assembly hole 612 is threaded. The bearing seat 71 is fixed on the first end face 51. The lead screw 72 passes through the bearing seat 71. One end of the lead screw 72 is connected to the radial adjustment knob 73, and the other end is threaded to the assembly hole 612.

[0037] Exemplary, in embodiments of this utility model, such as Figure 2 and Figure 4 As shown, rotating the radial adjustment knob 73 drives the lead screw 72 to rotate, allowing the needle holder 61 to move radially along the arc-shaped guide rail 2. This allows adjustment of the radial position of the needle holder 1 along the arc-shaped guide rail 2, facilitating radial adjustment of the needle tip position during use. This increases the degree of freedom of the adjuster and further enhances the ease of operation of the device. A corresponding scale and radial adjustment direction indicator are also provided on one side of the lead screw 72 on the guide slide 5, used to read the radial adjustment distance of the needle holder 1 and to calibrate the correspondence between the radial adjustment knob 73 and the radial movement direction.

[0038] Optionally, a guide rail 513 is provided on the first end face 51. The guide rail 513 is arranged radially along the arc-shaped guide rail 2, and a slot 64 matching the guide rail 513 is provided at the bottom of the needle holder 61.

[0039] Exemplary, in embodiments of this utility model, such as Figure 4 and Figure 5 As shown, the guide rail 513 adopts a dovetail structure, and correspondingly, the slot 64 is also a dovetail slot. The cooperation between the dovetail guide rail and the slot ensures that the needle holder 61 and the guide slide 5 can only move relative to each other along the radial direction of the arc-shaped guide rail 2, thereby improving the stability of this regulator.

[0040] Unless otherwise defined, the technical or scientific terms used herein shall have the ordinary meaning as understood by one of ordinary skill in the art to which this invention pertains. The terms “first,” “second,” and similar terms used in this patent application specification and claims do not indicate any order, quantity, or importance, but are merely used to distinguish different components. Similarly, the terms “an” or “a” and similar terms do not indicate a quantity limitation, but rather indicate the presence of at least one. The terms “comprising” or “including” and similar terms mean that the elements or objects preceding “comprising” or “including” encompass the elements or objects listed following “comprising” or “including” and their equivalents, and do not exclude other elements or objects. The terms “connected” or “linked” and similar terms are not limited to physical or mechanical connections, but can include electrical connections, whether direct or indirect. The terms “upper,” “lower,” “left,” and “right” are used only to indicate relative positional relationships; when the absolute position of the described object changes, the relative positional relationship may also change accordingly.

[0041] The above description is only an optional embodiment of the present utility model and is not intended to limit the present utility model. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A needle holder angle adjuster for micromanipulation, used to clamp and fix the needle holder (1) and adjust its angle, characterized in that, include: Arc-shaped guide rail (2), rack (3), drive gear (4) and guide slide (5). The rack (3) is arranged on the arc-shaped guide rail (2) along the extension direction of the arc-shaped guide rail (2). The guide slide (5) is slidably arranged on the arc-shaped guide rail (2) along the circumference of the arc-shaped guide rail (2). The needle holder (1) and the drive gear (4) are arranged on the guide slide. The needle holder (1) is arranged facing the center of the arc-shaped guide rail (2). The drive gear (4) is arranged on one side of the arc-shaped guide rail (2) and meshes with the rack (3). The other side of the arc-shaped guide rail (2) is provided with a limit wheel (521).

2. The needle holder angle adjuster for microscopic manipulation according to claim 1, characterized in that, Two limit wheels (521) are arranged at intervals, and a damping adjustment nut (522) is provided between the two limit wheels (521). The damping adjustment nut (522) abuts against the arc edge of the arc-shaped guide rail (2).

3. The needle holder angle adjuster for microscopic manipulation according to claim 1, characterized in that, The guide slide (5) has a first end face (51) and a second end face (52) opposite to each other. The needle holder (1) is disposed on the first end face (51). The drive gear (4) and the limiting wheel (521) are disposed on the second end face (52). The rack (3) is arranged along the outer edge of the arc-shaped guide rail (2). The outer edge of the limiting wheel (521) is in contact with the inner edge of the arc-shaped guide rail (2). The arc-shaped guide rail (2) has a third end face (21) and a fourth end face (22) opposite to each other. The third end face (21) is in contact with the second end face (52). The rack (3) is disposed on the fourth end face (22). A first limiting block (523) is disposed on the second end face (52). The first limiting block (523) is in contact with the outer edge of the arc-shaped guide rail (2).

4. The needle holder angle adjuster for microscopic manipulation according to claim 3, characterized in that, The rack (3) protrudes from the fourth end face (22), and a second limiting block (524) is provided on the first limiting block (523), with the second limiting block (524) located above the rack (3).

5. The needle holder angle adjuster for micromanipulation according to claim 3, characterized in that, The third end face (21) is provided with a first scale line (211), and the guide slide (5) is provided with a scale indicator window (53), and the scale indicator window (53) is provided with a scale pointer (531) that matches the first scale line (211).

6. The needle holder angle adjuster for micromanipulation according to claim 3, characterized in that, An angle adjustment knob (511) is provided on the first end face (51). The angle adjustment knob (511) rotates coaxially with the drive gear (4). A locking knob (512) is provided on one side of the angle adjustment knob (511).

7. The needle holder angle adjuster for micromanipulation according to claim 3, characterized in that, A clamping mechanism (6) is provided on the first end face (51). The clamping mechanism (6) includes a needle holder seat (61), a needle holder pressure block (62), and a fastening knob (63). The needle holder seat (61) is provided with a clamping groove (611) arranged radially along the arc-shaped guide rail (2). The needle holder (1) is disposed in the clamping groove (611). The needle holder pressure block (62) is slidably disposed on the top of the needle holder seat (61). The bottom of the needle holder pressure block (62) abuts against the needle holder (1). The fastening knob (63) is disposed on the top of the needle holder pressure block (62).

8. The needle holder angle adjuster for micromanipulation according to claim 7, characterized in that, The needle holder (1) is provided with a second scale line (11) and a needle holder limiting ring (12) is provided on the needle holder (1). The end of the needle holder limiting ring (12) abuts against one side of the needle holder seat (61).

9. A needle holder angle adjuster for microscopic manipulation according to claim 7, characterized in that, A radial adjustment mechanism (7) is provided on the first end face (51). The radial adjustment mechanism (7) includes a bearing seat (71), a lead screw (72) and a radial adjustment knob (73). The needle holder (61) is provided with an assembly hole (612) arranged radially along the arc-shaped guide rail (2). The assembly hole (612) is provided with a thread. The bearing seat (71) is fixed on the first end face (51). The lead screw (72) passes through the bearing seat (71). One end of the lead screw (72) is connected to the radial adjustment knob (73), and the other end is threaded to the assembly hole (612).

10. A needle holder angle adjuster for micromanipulation according to claim 9, characterized in that, A guide rail (513) is provided on the first end face (51). The guide rail (513) is arranged radially along the arc-shaped guide rail (2). The bottom of the needle holder (61) is provided with a slot (64) that matches the guide rail (513).

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