A support for a solid phase extraction column

Abstract

This application discloses a fixing bracket for a solid-phase extraction column, specifically relating to the field of solid-phase extraction column technology. It includes a base, a sleeve, a sliding rod, and a positioning ring fitted onto the opening of a flask. The sleeve is fixed to the upper end of the base, and the sliding rod is slidably installed within the sleeve. Correspondingly, a sliding groove is provided within the sleeve. The positioning ring is fixed to the upper end of the sliding rod, and the upper end of the solid-phase extraction column is tightly engaged with the upper surface of the positioning ring. The lower end outlet of the solid-phase extraction column is located inside the flask. This fixing bracket, by clamping and fixing the solid-phase extraction column from its upper edge, adjusts the distance between the lower opening of the solid-phase extraction column and the liquid surface, preventing the end of the column from immersing in the liquid surface.

Description

Technical Field

[0001] This application relates to the field of solid phase extraction column technology, and more particularly to a fixing support for a solid phase extraction column. Background Technology

[0002] Solid-phase extraction (SPE) is a commonly used pretreatment technique in laboratories. Currently, a common method for fixing the SPE column in laboratories involves inserting a plastic dropper or gasket between the open end of the flask and the SPE column, ensuring that the lower opening of the SPE column is above the inner surface of the flask. However, this method has the following disadvantages: 1. The SPE column cannot be kept vertical, affecting adsorption and elution efficiency; 2. It is difficult to adjust the distance between the lower end of the SPE column and the liquid surface, and there is a risk that the SPE column may fall directly into the flask during adjustment.

[0003] Therefore, how to adjust the position of the solid-phase extraction column in the vertical direction so that the lower end of the solid-phase extraction column does not contact the liquid surface inside the bottle is a problem that researchers urgently need to solve. Utility Model Content

[0004] This invention provides a fixing bracket for a solid phase extraction column. The fixing bracket is fastened to the upper edge of the solid phase extraction column, thereby adjusting the distance between the lower opening of the solid phase extraction column and the liquid surface, and preventing the end of the column from immersing in the liquid surface.

[0005] The objective of this utility model is achieved through the following technical solution: A fixing support for a solid phase extraction column includes a base, a sleeve, a slide bar, and a positioning ring fitted onto the opening end of a flask. The sleeve rod is fixed to the upper end of the base, and the slide rod is slidably installed in the sleeve rod. Correspondingly, the sleeve rod is provided with a sliding groove. The positioning ring is fixed to the upper end of the slide rod, and the upper end of the solid phase extraction column is in tight contact with the upper end face of the positioning ring. The liquid outlet at the lower end of the solid phase extraction column is located inside the heart-shaped bottle.

[0006] Preferably, the fixed bracket further includes a telescopic adjustment device, which includes a push ring and a rotating handle ring; the outer end of the sleeve rod is provided with a first fixing thread, and correspondingly, the inner end of the rotating handle ring is provided with a second fixing thread that is screwed and fixed to the first fixing thread; the push ring abuts against the lower end of the slide rod, and the push ring and the rotating handle ring are rotatably connected.

[0007] Preferably, the side end of the sleeve rod is provided with a through groove, and the push ring is provided with a slider adapted to the through groove, with the upper end of the slider abutting against the lower end of the slide rod.

[0008] Preferably, the push ring has a rotating groove on its side end, and correspondingly, the rotating handle ring has a rotating protrusion on its inner side that matches the rotating groove.

[0009] Preferably, a positioning block is provided on the inner side of the positioning ring, and the positioning block abuts against the lower side of the upper edge of the solid phase extraction column.

[0010] Preferably, the side end of the slide bar is provided with a limiting groove, and correspondingly, the sliding groove is provided with a limiting rib.

[0011] Preferably, both the upper and lower ends of the rotating handle ring are provided with arc-shaped force-applying edges.

[0012] Compared with the prior art, the advantages or beneficial effects of the technical solution of this application include: 1. By adjusting the extension and retraction of the sleeve and slide bar, the lower end of the solid-phase extraction column can be kept above the liquid surface inside the bottle. Simultaneously, the positioning ring design allows it to be smoothly locked onto the upper edge of the solid-phase extraction column, ensuring the column remains vertical during adsorption, thus facilitating adsorption and elution. Attached Figure Description

[0013] Figure 1 A schematic diagram (3D) of the use of a fixed support for a solid phase extraction column; Figure 2 A schematic diagram (front view) of the use of a fixed support for a solid phase extraction column; Figure 3 A 3D view of the combined state of the fixed bracket and the heart-shaped bottle; Figure 4 This is a cross-sectional view of the combined state of the fixed bracket and the heart-shaped bottle; Figure 5 for Figure 4 Enlarged view of part A in the image.

[0014] In the diagram: 1. Top panel, 2. Connecting column, 3. Fixing hole, 4. Bottom panel, 5. Solid phase extraction column, 6. Positioning ring, 7. Slide rod, 8. Limiting groove, 9. Sleeve rod, 10. Second fixing thread, 11. Rotating handle ring, 12. Base, 13. Chicken heart bottle, 14. Pushing ring, 15. Positioning block. Detailed Implementation

[0015] The following detailed description of the embodiments of this application, in conjunction with the accompanying drawings, will provide a thorough understanding of how this application uses technical means to solve technical problems and achieve corresponding technical effects, enabling its implementation. The embodiments of this application and the various features within them can be combined with each other without conflict, and all resulting technical solutions are within the protection scope of this application.

[0016] It should be clearly stated that the embodiments described below are merely some embodiments of this application, and not all embodiments. All other embodiments obtained by those skilled in the art based on the embodiments of this application without inventive effort are within the scope of protection of this application.

[0017] Example 1: This example provides a detailed explanation of the fixed support scheme: like Figures 1-5 As shown, a fixing support for a solid phase extraction column includes a base 12, a sleeve 9, a slide bar 7, and a positioning ring 6, which are sleeved on the open end of the heart-shaped bottle 13. The sleeve rod 9 is fixed to the upper end of the base 12, and the slide rod 7 is slidably installed in the sleeve rod 9. Correspondingly, the sleeve rod 9 is provided with a sliding groove. The positioning ring 6 is fixed to the upper end of the slide rod 7. The upper end of the solid phase extraction column 5 is in tight contact with the upper end face of the positioning ring 6, and the liquid outlet of the lower end of the solid phase extraction column 5 is located inside the heart-shaped bottle 13.

[0018] The fixed bracket also includes a telescopic adjustment device, which includes a push ring 14 and a rotating handle ring 11. The outer end of the sleeve rod 9 is provided with a first fixing thread, and correspondingly, the inner end of the rotating handle ring 11 is provided with a second fixing thread 10 that is screwed and fixed to the first fixing thread. The push ring 14 abuts against the lower end of the slide rod 7, and the push ring 14 and the rotating handle ring 11 are rotatably connected.

[0019] The sliding rod 7 and the sleeve rod 9 are slidably connected, allowing adjustment of the distance between the lower end of the solid-phase extraction column and the liquid surface. The upper edge of the solid-phase extraction column 5 is pressed against the positioning ring, keeping the solid-phase extraction column 5 in a vertical position, which facilitates the flow of sample liquid into the column.

[0020] The connection between slide bar 7 and sleeve bar 9 is achieved in the following way: The experimenter can rotate the rotating handle ring 11, causing the first fixed thread and the second fixed thread 10 to interact. With the sleeve rod position relatively fixed, rotating the handle ring 11 moves upward along the sleeve rod 9. The rotating handle ring 11 and the push ring 14 at the lower end of the slide rod 7 are rotatably connected in the horizontal direction and move synchronously in the vertical direction. Therefore, the push ring 14 can be driven to move upward or downward, which in turn drives the slide rod 7 to move upward or downward, thereby adjusting the distance between the small column and the liquid surface.

[0021] like Figure 3 As shown, the side end of the sleeve rod 9 is provided with a through groove, and the push ring 14 is provided with a slider adapted to the through groove. The upper end of the slider abuts against the lower end of the slide rod 7. After the slider passes through the through groove, it contacts the lower end of the slide rod 7, thereby applying force to the lower end of the slide rod 7.

[0022] like Figure 5As shown, the push ring 14 has a rotating groove on its side end, and correspondingly, the rotating handle ring 11 has a rotating protrusion on its inner side that matches the rotating groove. The cooperation between the rotating groove and the rotating protrusion achieves stability in the horizontal direction of rotation.

[0023] like Figure 3 and Figure 4 As shown, a positioning block 15 is provided on the inner side of the positioning ring 6, and the positioning block 15 abuts against the lower side of the upper edge of the solid phase extraction column 5.

[0024] In this embodiment, the side end of the slide bar 7 is provided with a limiting groove 8, and correspondingly, a limiting rib is provided in the sliding groove.

[0025] In this embodiment, both the upper and lower ends of the rotating handle ring 11 are provided with arc-shaped force-applying edges.

[0026] Example 2: Detection of pesticide residues in environmental water samples Experimental Background: An environmental monitoring laboratory needs to detect organophosphorus pesticide residues in water. Sample pretreatment requires enrichment of the target analyte using a C18 solid-phase extraction column, but traditional fixation methods (plastic dropper support) often cause the column to tilt, affecting the recovery rate.

[0027] Operating procedure for this bracket: Assembly: Place the base 12 onto the mouth of the 500mL heart-shaped bottle 13 (receiving bottle), and ensure that the sleeve rod 9 is vertically fixed.

[0028] Adjusting the height: Rotate the handle ring 11 to move the push ring 14 upward through the threaded transmission, which will drive the slide rod 7 and the positioning ring 6 to rise to a height of about 15cm (the preset distance from the bottle mouth to the liquid surface).

[0029] Fixing the column: Insert the upper end of the C18 solid phase extraction column 5 into the positioning ring 6, and the positioning block 15 will automatically fasten to the edge of the column to ensure a vertical state.

[0030] Observe the distance between the lower end of the column and the surface of the methanol (activation solution) in the receiving bottle, and finely adjust the rotating handle ring 11 to keep the distance 5mm.

[0031] Sample loading and elution: Pass 500 mL of water sample through the column at a flow rate of 5 mL / min. The stability of the support prevents channeling caused by column movement. During elution, readjust the handle ring to lower the column, ensuring the eluent drips away from the bottle wall.

[0032] Performance Comparison: Traditional methods result in fluctuating recovery rates (70%-85%), while this stent stabilizes the recovery rate at 92±2%. Adjustment time is reduced from 3-5 minutes to 30 seconds, and there is no risk of small columns falling off.

Claims

1. A fixing support for a solid phase extraction column, characterized in that, Includes a base (12) fitted onto the open end of the heart-shaped bottle (13), a sleeve (9), a slide bar (7), and a positioning ring (6); The sleeve rod (9) is fixed to the upper end of the base (12), and the slide rod (7) is slidably installed in the sleeve rod (9). Correspondingly, the sleeve rod (9) is provided with a sliding groove. The positioning ring (6) is fixed to the upper end of the slide bar (7), the upper end of the solid phase extraction column (5) is in tight contact with the upper end face of the positioning ring (6), and the liquid outlet at the lower end of the solid phase extraction column (5) is located inside the heart-shaped bottle (13).

2. The fixing support for a solid phase extraction column according to claim 1, characterized in that, It also includes a telescopic adjustment device, which includes a push ring (14) and a rotating handle ring (11). The outer end of the sleeve rod (9) is provided with a first fixing thread, and correspondingly, the inner end of the rotating handle ring (11) is provided with a second fixing thread (10) that is screwed and fixed to the first fixing thread. The push ring (14) abuts against the lower end of the slide rod (7), and the push ring (14) and the rotating handle ring (11) are rotatably connected.

3. The fixing support for a solid phase extraction column according to claim 2, characterized in that, The sleeve rod (9) has a through groove on its side end, and the push ring (14) has a slider that is adapted to the through groove. The upper end of the slider abuts against the lower end of the slide rod (7).

4. The fixing support for a solid phase extraction column according to claim 2, characterized in that, The push ring (14) has a rotating groove on its side end, and correspondingly, the rotating handle ring (11) has a rotating protrusion on its inner side that is adapted to the rotating groove.

5. The fixing support for a solid phase extraction column according to claim 1, characterized in that, The positioning ring (6) is provided with a positioning block (15) on its inner side, and the positioning block (15) is pressed against the lower side of the upper edge of the solid phase extraction column (5).

6. The fixing support for a solid phase extraction column according to claim 1, characterized in that, The side end of the slide bar (7) is provided with a limiting groove (8), and correspondingly, the sliding groove is provided with a limiting rib.

7. The fixing support for a solid-phase extraction column according to claim 1, characterized in that, The rotating handle ring (11) has arc-shaped force-applying edges at both the top and bottom.

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