Centrifugal microfluidic chip rapid fixing tool based on centrifuge equipment use

Abstract

The utility model relates to centrifugal micro -fluidic chip quick fixing frock technical field, concretely is a centrifugal micro -fluidic chip quick fixing frock based on centrifuge equipment uses, it is convenient to use, including frock main part, the top of frock main part is provided with four operation cabin, the top of every operation cabin all is provided with the reverse structure, the bottom of every operation cabin all is provided with two limit elastic sheet, every operation cabin all is provided with two reverse spring, the bottom middle part of frock main part is provided with the adapter spare, be provided with a plurality of location bolts between adapter spare and frock main part, every location bolt cooperates with adapter spare and frock main part.

Description

Technical Field

[0001] This utility model relates to the field of rapid fixation fixtures for centrifugal microfluidic chips, specifically a rapid fixation fixture for centrifugal microfluidic chips used in centrifuge equipment. Background Technology

[0002] As is well known, centrifugal microfluidics technology has made significant progress in the application of biomedical diagnostics. For example, centrifugal microfluidics devices can achieve fully automated platelet separation, which is of great significance for molecular diagnostics. Compared with traditional methods, this method not only improves the purity and yield of platelets, but also reduces platelet activation, thereby improving the accuracy of downstream analysis [3]. Similarly, centrifugal microfluidics platforms have also been used to develop high-throughput nucleic acid detection systems. These systems can complete the entire process from sample to result in a short time, greatly improving detection efficiency and accuracy. Moreover, the use of chips requires the support of external devices. The chips need to be connected to external transition and detection devices such as pumps and valves. This often results in existing devices being unable to be directly adapted, which will lead to a cumbersome experimental process and increase experimental costs. Incompatible devices also directly affect the stability and consistency of experimental results.

[0003] Since there are currently no centrifuges specifically designed for centrifugal chips on the market, if the centrifugation process of chips needs to be realized, existing centrifuges need to be used as the basic equipment and modified. Therefore, we propose a centrifugal microfluidic chip quick fixation fixture based on centrifuge equipment to solve the above problems. Utility Model Content

[0004] (a) Technical problems to be solved

[0005] To address the shortcomings of existing technologies, this invention provides a convenient and quick fixture for fixing centrifugal microfluidic chips used in centrifuge equipment.

[0006] (II) Technical Solution

[0007] To achieve the above objectives, this utility model provides the following technical solution: a rapid fixing fixture for centrifugal microfluidic chips used in centrifuge equipment, comprising a fixture body, four operating chambers at the top of the fixture body, an inverted structure at the top of each operating chamber, two limiting springs at the bottom of each operating chamber, two reverse springs in each operating chamber, a connecting part at the bottom center of the fixture body, and several positioning bolts between the connecting part and the fixture body, each positioning bolt cooperating with the connecting part and the fixture body.

[0008] Furthermore, an improvement of this invention is that the structure and size of the adapter part are customized according to the centrifuge to be connected.

[0009] Based on the above, the improvements of this utility model are that the edges of the tooling body, operating chamber, inverted structure, limiting spring, reverse spring and connecting parts are all rounded.

[0010] Furthermore, an improvement of this utility model is that the fit between each positioning bolt and the adapter part and the tooling body is a threaded fit.

[0011] (III) Beneficial Effects

[0012] Compared with the prior art, this utility model provides a rapid fixing fixture for centrifugal microfluidic chips used in centrifuge equipment, which has the following beneficial effects:

[0013] This centrifugal microfluidic chip quick-fixing fixture for centrifuge equipment, through the setting of fixture body, operating chamber, inverted structure, limiting spring, reverse spring and adapter parts, makes it easy to quickly fix and disassemble the chip during use. It is also easy to operate during transportation. The use effect of this centrifugal microfluidic chip quick-fixing fixture for centrifuge equipment is better. Attached Figure Description

[0014] Figure 1 This is a schematic diagram of the axial side structure of this utility model;

[0015] Figure 2 This is an axonometric sectional view of the present invention;

[0016] Figure 3 This is a schematic diagram of the axial structure of this utility model from another angle.

[0017] In the diagram: 1. Main tooling body; 2. Operating compartment; 3. Inverted structure; 4. Limiting spring; 5. Reverse spring; 6. Adapter parts. Detailed Implementation

[0018] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0019] Please see Figure 1-3This utility model discloses a quick-fixing fixture for centrifugal microfluidic chips used in centrifuge equipment. It includes a fixture body 1, with four operating chambers 2 at the top. Each operating chamber 2 has an inverted buckle structure 3 at its top, two limiting springs 4 at its bottom, and two reverse springs 5 ​​at its bottom. A connecting part 6 is located at the center of the bottom of the fixture body 1. The structure and size of the connecting part 6 are customized according to the centrifuge to be connected, facilitating connection of the quick-fixing fixture for centrifugal microfluidic chips to different models of centrifuges. A connection is established between the connecting part 6 and the fixture body 1. There are several positioning bolts, each of which mates with the adapter part 6 and the tooling body 1. The engagement between each positioning bolt and the adapter part 6 and the tooling body 1 is a threaded engagement, which allows the positioning bolts to fix the adapter part 6 and the tooling body 1. The edges of the tooling body 1, the operating chamber 2, the inverted structure 3, the limiting spring 4, the reverse spring 5, and the adapter part 6 are all rounded, so that the centrifugal microfluidic chip quick fixation tooling used in centrifuge equipment will not scratch the user during use. The centrifugal microfluidic chip quick fixation tooling used in centrifuge equipment facilitates quick fixation and disassembly of the chip during use, and it is also convenient to operate during transportation.

[0020] Centrifuges are high-speed rotating devices that generate significant radial forces during rotation, while maintaining a relatively constant direction of rotation. These two points are the main limiting structures, while other weak force directions are simplified. Considering the rotational nature of the tooling, the structural compartments are designed symmetrically, with a total of four compartments used in pairs. The tooling uses a fixed structure along its axial direction to restrict vertical freedom, and the chip body is pushed in from the side.

[0021] The main component of this invention is a standard glass slide measuring 75 mm in length and 25 mm in width. The fixture structure consists of a groove larger than twice the width of the chip, divided into two functional areas: an operating area and a reaction chamber. A spring is used to limit the chip's position after it enters the chamber. After the chip is inserted, a reverse spring 5 is pressed to restrict the chip's movement within the chamber. Furthermore, the reverse spring 5 actively ejects the chip from the chamber when it is removed, facilitating its removal. The connection between the fixture and the centrifuge is replaceable. Considering that different centrifuge models have different connection methods, the fixture's connection method is not designed in a single way. Instead, the connectors are designed separately to ensure that the connection between the connectors and the fixture remains unchanged. By designing connectors separately for different centrifuge models, only the different connectors need to be replaced when changing equipment, while the fixture can continue to be used.

[0022] In summary, this centrifugal microfluidic chip quick-fixing fixture for centrifuge equipment facilitates rapid chip fixing and removal during use. The chip is pressed into the operating chamber 2 from above the limiting spring 4, causing the spring to deform downwards, allowing the chip to be stacked into the operating chamber 2. The inverted structure 3 then restricts the chip from being pushed out from above. After the chip is pushed into place, the spring pops out, restricting the chip's lateral sliding. The chip continues to compress the inner reverse spring 5 after entering the chamber, providing a lateral thrust that stably holds the chip between the limiting spring 4 and the reverse spring 5. Removal is simple: press the limiting spring 4 with two fingers; the thrust of the directional spring pushes the chip out of the operating chamber 2. Releasing the pressing of the limiting spring 4 allows for chip removal. This centrifugal microfluidic chip quick-fixing fixture facilitates rapid chip fixing and removal, and is convenient for operation during transport. Therefore, this centrifugal microfluidic chip quick-fixing fixture offers superior performance.

[0023] The control method of this utility model is to control the device by manually starting and stopping the switch. The wiring diagram of the power element and the supply of power are common knowledge in the field. Since this utility model is mainly used to protect mechanical devices, the control method and wiring layout will not be explained in detail.

[0024] To better illustrate this embodiment, some parts in the accompanying drawings may be omitted, enlarged, or reduced, and do not represent the actual product dimensions.

[0025] Furthermore, unless otherwise defined, the technical or scientific terms used in this application description shall have the ordinary meaning understood by one of ordinary skill in the art to which this application pertains. The terms "upper," "lower," "left," "right," "center," "vertical," "horizontal," "inner," and "outer," etc., used in this application description to indicate relative direction or positional relationship are used only to indicate relative orientation or positional relationship, and do not imply that the device or component must have a specific orientation, or be constructed and operated in a specific orientation. When the absolute position of the described object changes, its relative positional relationship may also change accordingly, and therefore should not be construed as a limitation on this application. The terms "first," "second," "third," and similar terms used in this application description are used only for descriptive purposes to distinguish different components, and should not be construed as indicating or implying relative importance. The terms "a," "one," or "the," etc., used in this application description should not be construed as an absolute limitation on quantity, but should be construed as indicating the existence of at least one. The terms "including," "comprising," etc., used in this application description mean that the element or object preceding the word covers the element or object listed after the word and its equivalents, without excluding other elements or objects.

[0026] Furthermore, it should be noted that, unless otherwise explicitly specified and limited, terms such as “installation,” “connection,” and “linkage” used in the description of this application should be interpreted broadly. For example, a connection can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium; or it can be a connection within two components. Those skilled in the art can understand its specific meaning in this application according to the specific circumstances.

[0027] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A rapid fixation fixture for centrifugal microfluidic chips used in centrifuge equipment, comprising a fixture body (1), characterized in that: The tooling body (1) has four operating compartments (2) at its top. Each operating compartment (2) has an inverted structure (3) at its top. Each operating compartment (2) has two limiting springs (4) at its bottom. Each operating compartment (2) has two reverse springs (5). The tooling body (1) has a connecting part (6) at its bottom center. Several positioning bolts are provided between the connecting part (6) and the tooling body (1). Each positioning bolt cooperates with the connecting part (6) and the tooling body (1).

2. The rapid fixation fixture for centrifugal microfluidic chips used in centrifuge equipment according to claim 1, characterized in that: The structure and size of the adapter part (6) are customized according to the centrifuge to be connected.

3. The rapid fixation fixture for centrifugal microfluidic chips used in centrifuge equipment according to claim 1, characterized in that: The edges of the tooling body (1), operating chamber (2), inverted structure (3), limiting spring (4), reverse spring (5) and adapter part (6) are all rounded.

4. The rapid fixation fixture for centrifugal microfluidic chips used in centrifuge equipment according to claim 1, characterized in that: The engagement between each positioning bolt and the adapter part (6) and the tooling body (1) is a threaded engagement.

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