Hybrid acquisition methods incorporating multiple dissociation techniques
DE112015007331B4Pending Publication Date: 2026-07-02MICROMASS UK LTD
Patent Information
- Application Number
- DE112015007331
- Authority / Receiving Office
- DE · DE
- Patent Type
- Patents
- Current Assignee / Owner
- Priority Date
- 2014-04-17
- Filing Date
- 2015-04-17
- Publication Date
- 2026-07-02
- Estimated Expiration
- 2035-04-17
Abstract
A method is disclosed in which starting or precursor ions are fragmented or converted according to a first fragmentation or reaction operating mode, and the method then temporarily switches to a second fragmentation or reaction operating mode when an ion of interest is detected. This enables a complete, undistorted MS / MS dataset over a wide mass-to-charge ratio range with a high duty cycle, along with complementary detailed fragment data of interest, to be provided in a single trial or acquisition.
Need to check novelty before this filing date? Find Prior Art
Citation Information
Patent Citations
Data-dependent selection of dissociation type in a mass spectrometer
US20080048109A1
System and method for analyzing contents of sample based on quality of mass spectra
US20100288917A1
Methods for the analysis of glycoproteins or glycopeptides by mass spectrometry
US20140099725A1