Device for the controlled release of ablative energy to tissue using a pulsed electric field
Patent Information
- Application Number
- DE602019079464
- Authority / Receiving Office
- DE · DE
- Patent Type
- Patents
- Current Assignee / Owner
- Priority Date
- 2018-02-08
- Filing Date
- 2019-02-08
- Publication Date
- 2025-12-17
- Estimated Expiration
- 2039-02-08
AI Technical Summary
Existing methods for delivering pulsed electric fields for tissue therapeutics lack controlled and selective energy delivery, particularly in ablation therapy for cardiac arrhythmias, and there is a need for measured and controlled delivery of high voltage application to ensure safety and efficacy.
A system with a multi-channel voltage/signal generator and programmable controller applies voltage pulses to selected electrodes, using hierarchical waveforms and adaptive current control to ensure safe and effective irreversible electroporation, synchronized with cardiac pacing to avoid disrupting sinus rhythm.
The system enhances safety and efficiency of energy delivery by reducing the electric field threshold for irreversible electroporation, creating effective ablative lesions with reduced total energy, while minimizing damage to healthy tissue.