BIOMOLECULAR ONLINE INTERACTION ANALYSIS FOR MONITORING OR CONTROLLING BIOPROCESSES
Patent Information
- Authority / Receiving Office
- DE · DE
- Patent Type
- Patents
- Current Assignee / Owner
- SARTORIUS STEDIM BIOTECH GMBH
- Filing Date
- 2022-09-28
- Publication Date
- 2026-06-10
AI Technical Summary
Current bioprocess monitoring technologies are limited by the inability to perform rapid, automated, and on-line analysis of biologically active proteins, necessitating off-line sampling and manual handling, which hinders process control and development.
A fluidic manifold system for bioprocesses that integrates sensors for label-free biomolecular interaction analysis, enabling automated and on-line monitoring by using a fluidic manifold to withdraw discrete fluid samples and perform analysis with biosensors, allowing for low sample and reagent consumption.
Enables rapid, automated, and on-line analysis of biologically active proteins, facilitating process control and development with reduced sample and reagent use, and supporting high-throughput bioprocess monitoring.