New forms of ambrocenide®
Patent Information
- Authority / Receiving Office
- EP · EP
- Patent Type
- Applications
- Current Assignee / Owner
- Filing Date
- 2023-07-04
- Publication Date
- 2026-03-25
AI Technical Summary
Existing methods for producing Ambrocenide®, a powerful fragrance substance, result in an amorphous form that is challenging to handle and require costly purification processes, leading to yield losses and high manufacturing costs.
A method involving the partial or full melting of an unpurified synthesis product containing 70 to 98 wt.% of compound of formula (la) and 0.01 to 5 wt.% of compound of formula (Ib), followed by vapor treatment with a solvent like water, then contacting with a cold surface to achieve solidification, resulting in a particulate product with high crystallinity and ease of handling.
The method produces a particulate form of Ambrocenide® with almost identical olfactive properties to highly purified products, eliminating the need for solvents, reducing yield losses, and lowering production costs while maintaining excellent handling characteristics.
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Abstract
Citation Information
Patent Citations
(3aS,4aR,5S,7aS,9R,9aR)-2,2,5,8,8,9a-hexamethyloctahydro-4H-4a,9-methanoazuleno[5,6-d][1,3]dioxole
WO2019141881A1