Low radial force localizing stents

EP4687778A1Pending Publication Date: 2026-02-11BVW INVEST AG
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Patent Information

Application Number
EP2024722862
Authority / Receiving Office
EP · EP
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-03-29
Filing Date
2024-04-02
Publication Date
2026-02-11

AI Technical Summary

Technical Problem

Conventional stents face challenges with stent migration and tissue damage due to inadequate sizing and excessive radial force, leading to complications like paravalvular leakage, wall degeneration, and adverse biological processes such as thrombosis and in-stent restenosis.

Method used

The development of low radial force stents with microstructured surfaces, employing a Wenzel-Cassie interface that decouples radial force requirements from localization, utilizing hierarchical microstructures and surface energy patterns to achieve fixation without relying on high outward radial forces, allowing for reduced contact and frictional interaction with the lumenal surface.

Benefits of technology

These stents effectively reduce radial force and chronic complications, enabling more precise localization and patency while minimizing tissue damage and adverse reactions, facilitating easier delivery and reduced foreign body response.

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Abstract

Low radial force stents with good resistance to migration are described comprising microstructured surfaces which generate inward radially directed grip to a lumen. In particular, stents are described for deployment within biological lumens where a novel combination of low outwardly directed radial force and resistance to shear slippage within the lumen is achieved by hierarchical microstructured surfaces which provide non-frictional grip to the luminal surface. Combinations of microstructured surfaces which combine low radial force frictional grip and non-frictional grip which do not rely on axially dependent changes in stent diameter or stent oversizing are described. These combinations of microstructured surfaces when placed on the outer surface of a stent provide a non-migrating stent. The hierarchical levels of the disclosed microstructures may themselves by composites of microstructures, which may or may not be self-similar to other hierarchical levels.
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