Lipids, pharmaceutical compositions comprising the same and methods of delivering active pharmaceutical ingredients
Patent Information
- Authority / Receiving Office
- EP · EP
- Patent Type
- Applications
- Current Assignee / Owner
- Filing Date
- 2024-04-26
- Publication Date
- 2026-03-11
AI Technical Summary
There is a continuing need for lipid molecules and compositions that efficiently facilitate the transfection of nucleic acid molecules and other active pharmaceutical ingredients into cells, as existing methods often face limitations in uptake and delivery.
A lipid compound of Formula I or its pharmaceutically acceptable salt, which forms nanoparticles that encapsulate active pharmaceutical ingredients, enhancing transfection properties by specific structural features such as head groups, tail structures, and counter anions, is used to create effective lipid nanoparticles for delivery.
The lipid nanoparticles effectively deliver active pharmaceutical ingredients, such as siRNA, mRNA, and antisense oligonucleotides, by improving cellular uptake and transfection efficiency, addressing the limitations of existing methods.
Smart Images
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