STABILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME

The stability of thiopyridinone compounds in compositions for treating skin pigmentation is enhanced by incorporating a chelating agent, such as EDTA, which maintains the compound's effectiveness even under hot storage conditions.

FR3136667B1Active Publication Date: 2025-06-20LOREAL SA
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Patent Information

Application Number
FR2022007732
Authority / Receiving Office
FR · FR
Patent Type
Patents
Current Assignee / Owner
Priority Date
2022-06-21
Filing Date
2022-07-27
Publication Date
2025-06-20
Estimated Expiration
2042-07-27

AI Technical Summary

Technical Problem

Thiopyridinone compounds used in compositions for treating skin pigmentation spots tend to destabilize over time, especially when stored at elevated temperatures.

Method used

A composition comprising at least one thiopyridinone compound and a chelating agent, such as EDTA, is formulated to enhance the stability of the thiopyridinone compound, allowing it to maintain effectiveness even under hot storage conditions.

Benefits of technology

The inclusion of a chelating agent in the composition significantly increases the stability of the thiopyridinone compound, ensuring its efficacy over a longer period, including when stored at elevated temperatures.

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Abstract

STABILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME The present invention relates to a composition comprising: (1) at least one thiopyridinone compound; and (2) at least one chelating agent. The present invention can provide a composition including (1) thiopyridinone compound(s) exhibiting increased stability of the (1) thiopyridinone compound(s) over time, particularly even when the composition is maintained for a relatively long period at an elevated temperature. Figure for abstract: None
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