Apparatus, method and program for searching and training preferred retinal sites in patients with visual field damage

JP2024530798A5Active Publication Date: 2025-01-14THE ASAN FOUND +2
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Patent Information

Application Number
JP2024514376
Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
Priority Date
2021-09-06
Filing Date
2022-08-31
Publication Date
2025-01-14
Estimated Expiration
2042-08-31

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Benefits of technology

【0020】 前記のような本発明によると、専門医療陣の診断手続きなしに、刺激提供装置を通じて提供される行動課題だけで視野が損傷した患者の選好網膜部位を特定できる。

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Abstract

An apparatus, method and program for searching and training a preferred retinal site for a patient with visual field damage are provided, the method includes providing a first stimulus to the patient through a stimulus providing device linked to the apparatus, receiving a response to the first stimulus from the patient through the stimulus providing device, analyzing a head movement of the patient corresponding to the first stimulus if the response is correct, identifying the preferred retinal site based on the analyzed result, performing training related to central fixation of the patient, and performing training related to strengthening the preferred retinal site of the patient.
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Description

[Technical field]

[0001] The present invention relates to an apparatus, method and program for searching and training preferred retinal sites in patients with visual field damage. [Background technology]

[0002] Patients with damaged visual fields rely on the periphery of their damaged visual field (peripheral vision) to see, so it is important to identify the area of ​​peripheral vision used by the patient and provide consistent stimulation to strengthen the patient's peripheral vision.

[0003] Previously, a patient's preferred retinal locus (PRL) could be identified through specialized measurement methods such as microperimetry. However, this required a diagnosis by specialized medical staff, and there was a problem in that patients could not directly identify their own preferred retinal locus.

[0004] In addition, a method of strengthening peripheral vision through eccentric viewing training is being used for patients with visual field damage, but if the peripheral vision strengthened through training is not in the patient's preferred retinal area, the strengthened peripheral vision is not used in daily life, which reduces the efficiency of treatment.

[0005] Therefore, it is necessary to accurately measure the preferred retinal site of a visual field damaged patient and enhance the preferred retinal area that is primarily used by the patient, thereby improving the efficiency of enhancing the patient's peripheral vision. Summary of the Invention [Problem to be solved by the invention]

[0006] The present invention has been made in consideration of the above circumstances, and an object of the present invention is to provide an apparatus, method, and program for searching and training preferred retinal sites for patients with visual field damage.

[0007] The problems to be solved by the present invention are not limited to those mentioned above, and other problems not mentioned will be clearly understood by those skilled in the art from the following description. [Means for solving the problem]

[0008] A method for searching for a preferred retinal site in a patient with visual field damage according to one embodiment of the present invention for solving the above-mentioned problems includes the steps of providing a first stimulus to the patient through a stimulus providing device linked to the apparatus, receiving a response to the first stimulus from the patient through the stimulus providing device, and if the response is correct, analyzing the patient's head movement corresponding to the first stimulus, and identifying the preferred retinal site based on the analyzed result, wherein the preferred retinal site is set as a target for training at least one of the patient's visual acuity and visual cognitive ability, and a second stimulus is provided.

[0009] In the present invention, the step of analyzing the patient's head movement comprises analyzing the head position changed due to the head movement from an initial position of the patient's head in two-dimensional coordinates, and the initial position may be the head position when the patient's line of sight is fixed at the center of the screen of the stimulation providing device using two lines intersecting the center of the screen.

[0010] In the present invention, the step of providing the first stimulus may include repeatedly providing the first stimulus until a pre-set condition is satisfied, and the step of receiving the response may include receiving a plurality of responses to each of the plurality of first stimuli repeatedly provided.

[0011] In the present invention, the step of analyzing the patient's head movements classifies only the correct responses among the plurality of responses into one or more clusters, and the patient's preferred retinal site can be predicted based on the results of classification into the one or more clusters.

[0012] In the present invention, the step of identifying the preferred retinal site may identify the preferred retinal site of the patient through principal component analysis on the one cluster.

[0013] In the present invention, the first stimulus may include a behavioral task requiring a judgment as to whether an orientation displayed in the center of the screen is horizontal or vertical, and the second stimulus may include a training task utilizing a collinear arrangement of target stimuli and peripheral stimuli provided to the patient's preferred retinal site.

[0014] In one embodiment of the present invention, a method for training a preferred retinal site of a patient with visual field damage for solving the above-mentioned problems includes a step of performing training related to the patient's central fixation and a step of performing training related to strengthening the patient's preferred retinal site, and the preferred retinal site is identified by a search method that analyzes the patient's head movement in response to a first stimulus provided to the patient through a stimulus providing device linked to the device.

[0015] In the present invention, the step of performing training related to central fixation may include displaying a diagonal line across the patient's visual field through the stimulus providing device and requesting the patient to gaze at a point expected to be the intersection of the diagonal line.

[0016] In the present invention, the step of performing training related to strengthening the preferred retinal location may include providing a second stimulus to the preferred retinal location through the stimulus providing device and requesting the patient to detect the second stimulus.

[0017] In the present invention, the first stimulus may include a behavioral task requiring a judgment as to whether an orientation displayed in the center of a screen of the stimulus providing device is horizontal or vertical, and the second stimulus may include a training task utilizing a collinear arrangement of target stimuli and peripheral stimuli provided to the preferred retinal site.

[0018] A method for searching for and training a preferred retinal site in a patient with visual field damage according to one embodiment of the present invention for solving the above-mentioned problems includes the steps of providing a first stimulus to the patient through a stimulus providing device linked to the apparatus, receiving a response to the first stimulus from the patient through the stimulus providing device, and if the response is correct, analyzing the patient's head movement corresponding to the first stimulus, identifying the preferred retinal site based on the analyzed result, performing training related to the patient's central fixation, and performing training related to strengthening the patient's preferred retinal site.

[0019] In addition, other methods for implementing the present invention, other systems, and computer-readable recording media having computer programs recorded thereon for carrying out the methods can also be provided. Effect of the Invention

[0020] According to the present invention, the preferred retinal region of a patient with impaired visual field can be identified by only a behavioral task provided through a stimulation device, without the need for a diagnostic procedure by a specialized medical team.

[0021] Also, by inducing central fixation in the patient, sustained stimulation of a portion of the peripheral vision can be induced to develop a preferred retinal site.

[0022] In addition, by enhancing the patient's preferred retinal area, the peripheral vision that can be utilized in the patient's real life can be enhanced, improving the efficiency of treatment.

[0023] The effects of the present invention are not limited to those mentioned above, and other effects not mentioned will be clearly understood by those skilled in the art from the following description. [Brief description of the drawings]

[0024] [Figure 1] 1 is a block diagram of a device for locating a preferred retinal site in a patient with visual field damage according to an embodiment of the present invention. [Diagram 2]2 is a flow chart of a method for searching for a preferred retinal site in a patient with visual field damage according to an embodiment of the present invention. [Diagram 3] FIG. 2 is a diagram illustrating preferred retinal sites in a patient with visual field damage according to an embodiment of the present invention. [Figure 4] 1A to 1C are diagrams illustrating a method for analyzing two-dimensional coordinates according to head movement in accordance with an embodiment of the present invention. [Diagram 5] 1A to 1C are diagrams illustrating a method for analyzing two-dimensional coordinates according to head movement in accordance with an embodiment of the present invention. [Figure 6] 1 is a block diagram of a preferred retinal site training device for a visual field damaged patient according to an embodiment of the present invention. [Figure 7] 1 is a flow chart of a method for training a preferred retinal site of a patient with visual field damage according to an embodiment of the present invention; [Figure 8] FIG. 1 is a diagram illustrating central fixation training according to an embodiment of the present invention. [Figure 9] 1 is a block diagram of a preferred retinal site exploration and training device for visual field damage patients according to an embodiment of the present invention. [Figure 10] 1 is a flow chart of a method for searching and training preferred retinal sites for a patient with visual field damage according to an embodiment of the present invention. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0025] The advantages and features of the present invention, and the methods for achieving them, will become clear from the following detailed description of the embodiments in conjunction with the accompanying drawings. However, the present invention is not limited to the embodiments disclosed below, and may be realized in various different forms. However, the embodiments are provided to complete the disclosure of the present invention and to allow those skilled in the art to fully understand the scope of the present invention, and the present invention is only defined by the scope of the claims.

[0026] The terms used in this specification are for the purpose of describing the embodiments and are not intended to limit the present invention. In this specification, the singular includes the plural unless otherwise specified. The terms "comprises" and / or "comprising" used in this specification do not exclude the presence or addition of one or more other components other than the components mentioned. The same reference numerals throughout this specification refer to the same components, and "and / or" includes each and every combination of one or more of the components mentioned. Even if "first", "second", etc. are used to describe various components, these components are not limited by these terms. These terms are used simply to distinguish one component from another component. Therefore, it goes without saying that the first component mentioned below may also be the second component within the technical spirit of the present invention.

[0027] Unless otherwise defined, all terms (including technical and scientific terms) used in this specification are used as meanings commonly understood by ordinary skilled artisans in the technical field to which the present invention belongs. Furthermore, terms defined in commonly used dictionaries are not interpreted ideally or excessively unless clearly and specifically defined.

[0028] Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings.

[0029] Prior to the description, the meanings of the terms used in this specification will be briefly explained. However, since the explanations of the terms are intended to facilitate understanding of this specification, it should be noted that unless explicitly stated as matters limiting the present invention, they are not used to limit the technical ideas of the present invention.

[0030] The present invention seeks out and trains preferred retinal sites to improve at least one of the visual acuity and visual cognitive ability of patients with visual field damage, and due to the therapeutic effect achieved through searching and training preferred retinal sites, the present invention can be applied as a digital therapeutic agent.

[0031] Digital therapeutics refer to digital healthcare that is used like surgery, treatment, or medicine to treat patients. Digital therapeutics use software such as applications, games, VR, chatbots, and artificial intelligence, and the software alone can act as a therapeutic agent, or the software built into hardware medical devices can act as a therapeutic agent.

[0032] In this specification, the term "computer" includes all kinds of devices capable of performing arithmetic processing. For example, the computer may include not only a desktop PC and a notebook computer, but also a smart phone, a tablet PC, a cellular phone, a PCS phone (Personal Communication Service phone), a synchronous / asynchronous IMT-2000 (International Mobile Telecommunication-2000) mobile terminal, a Palm PC (Palm Personal Computer), a personal digital assistant (PDA), and the like. In addition, the computer may include a head-mounted display function, and the head-mounted display device itself may be a computing device. The term includes a computer being a computing device connected to a head-mounted display device by wire or wirelessly, and the computing device providing an image to the head-mounted display. The term includes a computer being a head-mounted display computing device itself, and performing operations from generating to providing an image. The computer may also be a server computer that receives information from a client. Hereinafter, in this specification, the computer may be expressed as a device, a terminal, or a client.

[0033] In this specification, the term "head mounted display device" refers to a device that provides images (stimuli) to the eyes of a user (patient) for searching and training preferred retinal sites. The present invention is a method for searching and training preferred retinal sites in two dimensions and three dimensions (virtual reality, VR), which uses a "head mounted display device" when performed in three dimensions. The "head mounted display device" may be a device that is used in connection with a computer (e.g., a PC or a smartphone) or a device that includes a computing function.

[0034] In this specification, the "screen" provided to the user (patient) includes a separate display screen when training is performed in two dimensions, and includes a screen on a head-mounted display device worn by the user when training is performed in three dimensions.

[0035] In this specification, the term "device" includes all kinds of devices capable of performing arithmetic processing and providing a result to a user. For example, the device may be in the form of a computer or a mobile terminal. The computer may be in the form of a server that receives a request from a client and processes information. The computer may also be a sequencing device that performs sequencing. The mobile terminal may include a mobile phone, a smart phone, a personal digital assistant (PDA), a portable multimedia player (PMP), a navigation system, a notebook computer, a slate PC, a tablet PC, an ultrabook, a wearable device (e.g., a smartwatch, smart glass, a head mounted display (HMD)), and the like.

[0036] The "stimulus providing device" in this specification may be a monitor-type display device that provides 2D-type stimuli to a patient with visual field damage, or a virtual reality device (EX, HMD, GLASS, etc.) that is worn by a patient with visual field damage and provides 3D-type stimuli based on virtual reality (AR, VR, XR, etc.).

[0037] In this specification, the term "visual field damaged patient" may include any patient who has at least one of the visual acuity and visual perception ability in a specific area of ​​the overall visual field damaged or lost and cannot perceive objects in a normal manner, such as a patient with macular degeneration or a patient with glaucoma who has lost central vision and cannot see the central visual field area and must perceive objects through peripheral vision.

[0038] "Stimulus" in this specification may refer to visual stimuli (gabor) provided to a visual field damaged patient. Through various types of visual stimuli, the preferred retinal site of a visual field damaged patient can be explored and the explored preferred retinal site can be trained. "Stimulus" can be in a two-dimensional form or a three-dimensional form.

[0039] Hereinafter, a method for searching for a preferred retinal site in a patient with visual field damage will be specifically described with reference to FIGS.

[0040] FIG. 1 is a block diagram of an apparatus for locating a preferred retinal site in a patient with visual field damage according to an embodiment of the present invention.

[0041] FIG. 2 is a flow chart of a method for searching for a preferred retinal site in a patient with visual field damage according to an embodiment of the present invention.

[0042] FIG. 3 is a diagram illustrating the preferred retinal site of a visual field damaged patient according to an embodiment of the present invention.

[0043] 4 and 5 are diagrams illustrating a method for analyzing two-dimensional coordinates according to head movement according to an embodiment of the present invention.

[0044] Referring to FIG. 1, a preferred retinal site location device 10 for a visual field damaged patient according to an embodiment of the present invention (hereinafter referred to as preferred retinal site location device) includes a processor 11, a communication unit 12, and a memory 13.

[0045] However, in some embodiments, the preferred retinal site location device 10 may include fewer or more components than those shown in FIG.

[0046] For example, the preferred retinal site searching device 10 may further include an input / output unit that receives various control signals from a user / administrator of the device and outputs the results.

[0047] The communication unit 12 can provide a stimulus to the visual field damage patient through the stimulus providing device, and can receive a response to the stimulus from the visual field damage patient through the stimulus providing device.

[0048] The visual field damage patient can use (or more specifically, wear) the stimulus provision device to view stimuli displayed on a screen and input responses to the stimuli.

[0049] The memory 13 stores the responses to the stimuli obtained through the communication unit 12 and the results of the execution of the method for searching for preferred retinal sites of the visual field damaged patient.

[0050] In addition, the memory 13 stores various commands, algorithms, etc. for carrying out the method for searching for the preferred retinal site of the visual field damaged patient.

[0051] The processor 11 controls the configuration within the preferred retinal site searching device 10 .

[0052] The preferred retinal site searching device 10 according to the embodiment of the present invention can be configured by a computer or an information processing device, and preferably by a preferred retinal site searching server.

[0053] A method for searching for a preferred retinal site in a patient with visual field damage by the preferred retinal site searching device 10 according to the embodiment of the present invention will be described in detail below with reference to FIG.

[0054] The preferred retinal site location device 10 can provide a first stimulus to the visual field damage patient through a stimulus providing device linked to the device 10 through a communication unit 12 (S110).

[0055] The preferred retinal site location device 10 can receive a response to the first stimulus from the visual field damage patient through the stimulus providing device via the communication unit 12 (S120).

[0056] If the response is correct, the processor 11 of the preferred retinal site location device 10 can analyze the head movement of the visual field damage patient in response to the first stimulus (S130).

[0057] The processor 11 of the preferred retinal site searching device 10 can identify the preferred retinal site based on the analyzed results (S140).

[0058] Here, the stimulus providing device and the preferred retinal site location device 10 can be realized as separate devices connected to each other by wire or wirelessly, or the stimulus providing device and the preferred retinal site location device 10 can be realized as an integrated device.

[0059] Here, the first stimulus may include a behavioral task that requests the user to judge whether the orientation displayed at the center of the screen of the stimulus providing device is horizontal or vertical, but is not limited thereto, and the first stimulus may be provided in various forms as a behavioral task for searching for a preferred retinal site of the visual field damaged patient.

[0060] More specifically, the first stimulus may be a behavioral task in which the visual field damage patient fixes his / her eyes on the center of the screen using two line segments intersecting the center of the screen of the stimulus providing device, and then searches for the corresponding first stimulus presented in the center of the screen and matches its orientation to whether it is horizontal or vertical.

[0061] As shown in Figure 3, visual field damage patients have damaged central vision and perceive objects through a specific location in the peripheral vision called the preferred retinal region (PRL). Since the preferred retinal region differs from patient to patient, it is important to accurately find where the preferred retinal region of each patient is located.

[0062] Because the visual field damaged patient has damage to the central vision (absolute scotoma), he or she moves their head to locate the first stimulus presented on the screen, and the head movement can be used to identify the patient's preferred retinal location.

[0063] More specifically, the processor 11 can analyze the initial position of the head of the visual field damage patient and the position of the head changed by the movement of the head in two-dimensional coordinates.

[0064] Here, the initial position may refer to the position of the head when the visual field damage patient's gaze is fixed at the center of the screen of the stimulation providing device using two lines intersecting the center of the screen.

[0065] The processor 11 can convert the movement results of the head (neck) of the visual field damaged patient into spatial coordinates using a gyroscope built into the stimulation providing device, and output the two-dimensional coordinates of the position reached by rotation from the initial position.

[0066] The processor 11 can use the head movement of the visual field damaged patient when the response was received for analysis only if it is determined that the visual field damaged patient has used head movement appropriately to use the preferred retinal site (i.e., only if the response to the first stimulus is correct).

[0067] In step S110, the processor 11 may repeatedly provide the first stimulus until a pre-set condition is met.

[0068] At step S120, the processor 11 may receive a plurality of responses to each of the repeatedly provided plurality of first stimuli.

[0069] Here, the pre-set condition may be whether a minimum number of response data for data analysis has been collected or whether a maximum number of first stimuli has been presented.

[0070] That is, the processor 11 can repeatedly provide the first stimulus to the visual field damaged patient, and when the number of correct response data received from the patient reaches a minimum number, the processor 11 can terminate providing the first stimulus to the patient. Alternatively, the processor 11 can repeatedly provide the first stimulus to the visual field damaged patient, and when the number of times the first stimulus has been provided to the patient reaches a maximum number, the processor 11 can terminate providing the first stimulus to the patient.

[0071] In step S130, the processor 11 classifies only the correct responses among the plurality of responses into one or more clusters, and can predict the preferred retinal site of the visual field damage patient based on the results of classification into the one or more clusters.

[0072] In step S140, the processor 11 can identify the preferred retinal region of the visual field damage patient through principal component analysis on the one cluster.

[0073] The processor 11 can use density-based spatial clouding of applications with noise (DBSAN) to analyze in real time the two-dimensional coordinate results for the movement at the time the patient answered correctly.

[0074] Referring to FIG. 4, the processor 11 classifies each two-dimensional coordinate into one or more clusters using an algorithm depending on whether it is spatially adjacent or not, and information that is not classified into a cluster can be classified as an outlier.

[0075] In this way, the areas corresponding to the clustering results for the two-dimensional coordinates correspond to the areas of the predicted preferred retinal sites of patients with visual field damage, and patients with visual field damage in which one or more clusters are formed in a single form can be shown to have well-localized preferred retinal sites.

[0076] Referring to FIG. 5, the processor 11 performs a principal component analysis (PCA) on one of the clusters analyzed in step S130, extracts a line segment (eigenvalue, eigenvector) that best represents the corresponding cluster from the PCA, and can use the extracted line segment, together with the average two-dimensional coordinate of the cluster, as an element of a training stimulus array that can produce an optimal effect on the preferred retinal site of the visual field damaged patient.

[0077] In this way, the present invention uses a gyroscope to measure the head movement of a patient with visual field damage in response to a visual stimulus (first stimulus) provided from a stimulus providing device, and can analyze the movement of the patient with visual field damage due to the stimulus to identify the preferred retinal site (PRL) of the patient with visual field damage.

[0078] The preferred retinal region thus identified may be set as a target for training at least one of the visual acuity and visual perception ability of the visual field damaged patient, and a second stimulus may be provided to the preferred retinal region, where the second stimulus may include a training task using a collinear array of target stimuli and peripheral stimuli provided to the preferred retinal region of the visual field damaged patient, which will be described in detail later.

[0079] That is, the preferred retinal region identified through steps S110 to S140 can be used to perform steps S210 and S220, which will be described later.

[0080] Hereinafter, a method for training a preferred retinal site of a patient with visual field damage will be specifically described with reference to FIGS.

[0081] FIG. 6 is a block diagram of a preferred retinal site training device for a visual field damaged patient according to an embodiment of the present invention.

[0082] FIG. 7 is a flowchart of a method for training a preferred retinal site of a patient with visual field damage according to an embodiment of the present invention.

[0083] FIG. 8 is a diagram for explaining central fixation training according to an embodiment of the present invention.

[0084] 6, a preferred retinal site training device 20 for a visual field damaged patient according to an embodiment of the present invention (hereinafter, referred to as preferred retinal site training device) includes a processor 21, a communication unit 22, and a memory 23.

[0085] However, in some embodiments, preferred retinal location training device 20 may include fewer or more components than those shown in FIG.

[0086] For example, the preferred retinal site training device 20 may further include an input / output unit that receives various control signals from a user / administrator of the device and outputs the results.

[0087] The communication unit 22 can provide a stimulus to the visual field damage patient through the stimulus providing device, and can receive a response to the stimulus from the visual field damage patient through the stimulus providing device.

[0088] The visual field damage patient can use (or more specifically, wear) the stimulus provision device to view stimuli displayed on a screen and input responses to the stimuli.

[0089] The memory 23 stores the responses to the stimuli obtained through the communication unit 22 and the results of the execution of the preferred retinal site training method for the visual field damaged patient.

[0090] In addition, the memory 23 stores various commands, algorithms, etc. for carrying out the preferred retinal site training method for visual field damaged patients.

[0091] The processor 21 controls the configuration within the preferred retinal site training device 20 .

[0092] The preferred retinal area training device 20 according to the embodiment of the present invention can be configured with a computer or an information processing device, and preferably can be configured with a preferred retinal area training server.

[0093] Hereinafter, with reference to FIG. 7, a method for training a preferred retinal site of a visual field damaged patient by the preferred retinal site training device 20 according to the embodiment of the present invention will be described in detail.

[0094] The processor 21 of the preferred retinal site training device 20 can perform training related to central fixation of the visual field damaged patient (S210).

[0095] The processor 21 of the preferred retinal site training device 20 can perform training related to strengthening the preferred retinal site of the visual field damaged patient (S220).

[0096] Here, the preferred retinal region can be identified by a search method that analyzes the head movement of the visual field damaged patient according to a first stimulus provided to the visual field damaged patient through a stimulus providing device linked to the device. Here, the first stimulus can include a behavioral task that requires the patient to judge whether the orientation displayed at the center of the screen of the stimulus providing device is horizontal or vertical. A detailed description will be omitted as it overlaps with the above description.

[0097] As described above, visual field damage patients perform eccentric vision through their preferred retinal region (PRL), but this requires tilting the head to view, which may cause inconvenience to the patient as they must be aware of other people's gazes. Therefore, by developing the preferred retinal region through training in steps S210 and S220 for the preferred retinal region identified through steps S110 to S140, the patient can recognize objects even with peripheral vision.

[0098] More specifically, in step S210, the processor 21 may display a diagonal line across the visual field of the visual field of the visual field damaged patient through the stimulus providing device and request the visual field damaged patient to gaze at a point that is expected to be the intersection of the diagonal line.

[0099] 8, when a visual stimulus providing device provides a virtual diagonal line (visual queue) across the visual field of a patient with impaired visual field for central fixation, the patient can gaze at a point that is expected to be the intersection of the diagonal line, thereby inducing central fixation of the patient.

[0100] Thereafter, in step S220, the processor 21 can provide a second stimulus to the preferred retinal location through the stimulus providing device and request the visual field damage patient to detect the second stimulus.

[0101] Here, the second stimulus may include a training task utilizing a collinear array of target and peripheral stimuli presented to the preferred retinal location.

[0102] More specifically, the second stimulus may be a temporal two alternative forced choice (temporal 2-AFC) task using a collinear array of target and peripheral stimuli provided to the patient's preferred retinal region, in which the patient is asked to respond as to which screen is the screen presented together with the target stimulus located in the center of the array.

[0103] Here, a collinear arrangement may refer to a stimulus arrangement in which the angle between a target stimulus and a peripheral stimulus arranged in a row is the same as the angle within the second stimulus.

[0104] Collinear arrays of stimuli can be characterized by lateral interaction, whereby detection of a target stimulus is difficult when the stimuli are close together and easy when the stimuli are far apart; this can be understood as a result of the size of the human receptive field.

[0105] Systematic manipulation of the interstimulus distance (λ) and spatial frequency (σ) of the second stimulus provided for training can ultimately change the size of the receiving field and increase the transferability of the visual perceptual learning effect. Transfer means that the effect goes beyond the detection / discrimination sensitivity of the second stimulus after training to also affect higher levels of visual processing (e.g., reading ability), and the poor reading ability characterized by weak peripheral vision in patients with visual field damage can be improved after training.

[0106] In this way, the present invention continuously provides a second stimulus capable of strengthening the preferred retinal site of a visual field damaged patient while inducing central fixation, and induces continuous stimulation in a certain part of the patient's peripheral vision, thereby developing the preferred retinal site, thereby enabling the patient to strengthen his or her peripheral vision in real life and improving the efficiency of treatment.

[0107] In the above, it has been described that the stimulus providing device for providing the first stimulus and the stimulus providing device for providing the second stimulus are the same, but depending on the embodiment, these two devices may be different from each other. That is, the stimulus providing device for providing the first stimulus is connected to the preferred retinal site searching device 10 when the preferred retinal site searching device 10 performs the preferred retinal site searching method to transmit and receive various data, signals, and information, and the stimulus providing device for providing the second stimulus is connected to the preferred retinal site training device 20 when the preferred retinal site searching device 10 performs the preferred retinal site training method to transmit and receive various data, signals, and information. And, the search result of the preferred retinal site performing the preferred retinal site searching method can be transmitted and received between the preferred retinal site searching device 10 and the preferred retinal site training device 20.

[0108] Hereinafter, a method for searching for and training a preferred retinal site of a patient with visual field damage will be specifically described with reference to FIGS.

[0109] FIG. 9 is a block diagram of a preferred retinal site searching and training device for a visual field damaged patient according to an embodiment of the present invention.

[0110] FIG. 10 is a flowchart of a method for searching and training preferred retinal sites for a patient with visual field damage according to an embodiment of the present invention.

[0111] Referring to FIG. 9, an apparatus 30 for searching and training a preferred retinal site for a patient with visual field damage according to an embodiment of the present invention (hereinafter referred to as a preferred retinal site searching and training apparatus) includes a processor 31, a communication unit 32, and a memory 33.

[0112] However, in some embodiments, the preferred retinal location searching and training apparatus 30 may include fewer or more components than those shown in FIG.

[0113] For example, the preferred retinal site searching and training device 30 may further include an input / output unit for receiving various control signals from a user / administrator of the device and for outputting the results.

[0114] The communication unit 32 can provide a stimulus to the visual field damage patient through the stimulus providing device, and can receive a response to the stimulus from the visual field damage patient through the stimulus providing device.

[0115] The visual field damage patient can use (or more specifically, wear) the stimulus provision device to view stimuli displayed on a screen and input responses to the stimuli.

[0116] The memory 33 stores the responses to the stimuli obtained through the communication unit 32 and the results of the search for and training of the preferred retinal sites of the visual field damaged patient.

[0117] In addition, the memory 33 stores various commands and algorithms for performing the method of searching for and training the preferred retinal site of the visual field damaged patient.

[0118] The processor 31 controls the configuration within the preferred retinal site searching and training device 30 .

[0119] The preferred retinal site searching and training device 30 according to the embodiment of the present invention can be configured as a computer or an information processing device, and preferably as a preferred retinal site searching and training server.

[0120] Hereinafter, with reference to FIG. 10, a method for searching and training a preferred retinal site of a patient with visual field damage by the preferred retinal site searching and training device 30 according to an embodiment of the present invention will be described in detail.

[0121] The preferred retinal region searching and training device 30 can provide a first stimulus to the visual field damage patient through a stimulus providing device linked to the device 30 via a communication unit 32 (S310).

[0122] The preferred retinal site searching and training device 30 can receive a response to the first stimulus from the visual field damage patient through the stimulus providing device via the communication unit 32 (S320).

[0123] If the response is correct, the processor 31 of the preferred retinal site searching and training device 30 may analyze the head movement of the visual field injury patient in response to the first stimulus (S330).

[0124] The processor 31 of the preferred retinal site searching and training device 30 can identify the preferred retinal site based on the analyzed results (S340).

[0125] The processor 31 of the preferred retinal site searching and training device 30 can perform training related to central fixation of the visual field damaged patient (S350).

[0126] The processor 31 of the preferred retinal site searching and training device 30 can perform training related to strengthening the preferred retinal site of the visual field damaged patient (S360).

[0127] Here, steps S310 to S340 are the same as steps S110 to S140 described above with reference to Figures 1 to 5, and steps S350 and S360 are the same as steps S210 and S220 described above with reference to Figures 6 to 8, so detailed description of steps S310 to S360 will be omitted.

[0128] That is, the preferred retinal site searching and training device 30 can function as both the preferred retinal site searching device 10 and the preferred retinal site training device 20. In this case, the stimulus providing device that provides the first stimulus and the stimulus providing device that provides the second stimulus may be the same.

[0129] The method according to the embodiment of the present invention described above can be realized as a program (or application) executed by a server, which is hardware, and stored in a medium. Here, the server can be at least one of the preferred retinal site search server, the preferred retinal site training server, and the preferred retinal site search and training server described above.

[0130] The above-mentioned program may include code coded in a computer language such as C, C++, JAVA, machine language, etc., which is read by the processor (CPU) of the computer through the device interface of the computer so that the computer can read the program and execute the method realized by the program. Such code may include functional code related to functions defining functions necessary to execute the method, and may include control code related to execution procedures necessary for the processor of the computer to execute the function according to a predetermined procedure. In addition, such code may further include memory reference-related code for referring to a location (address) of the internal or external memory of the computer where additional information or media necessary for the processor of the computer to execute the function should be referenced. Furthermore, if the processor of the computer needs to communicate with any other remote computer or server to execute the function, the code may further include communication-related code for how to communicate with any other remote computer or server using a communication module of the computer, and what information or media should be sent or received during communication.

[0131] The storage medium refers to a medium that stores data semi-permanently and can be read by a device, rather than a medium that stores data for a short time such as a register, cache, memory, etc. Specifically, examples of the storage medium include, but are not limited to, ROM, RAM, CD-ROM, magnetic tape, floppy disk, optical data storage device, etc. That is, the program can be stored in various recording media on various servers to which the computer can be connected or various recording media on the user's computer. Also, the medium can be distributed among computer systems connected by a network and store computer-readable code in a distributed manner.

[0132] The steps of a method or algorithm described in connection with the embodiments of the present invention may be implemented directly in hardware, or in a software module executed by hardware, or a combination thereof. The software module may be present in a Random Access Memory (RAM), a Read Only Memory (ROM), an Erasable Programmable ROM (EPROM), an Electrically Erasable Programmable ROM (EEPROM), a Flash Memory, a hard disk, a removable disk, a CD-ROM, or any other form of computer readable storage medium known in the art to which the present invention pertains.

[0133] Although the embodiments of the present invention have been described above with reference to the accompanying drawings, those skilled in the art will understand that the present invention can be embodied in other specific forms without changing the technical spirit or essential features of the present invention. Therefore, the above-described embodiments should be understood as illustrative in all respects and not restrictive.

Claims

1. A method for searching for a preferred retinal site in a patient with visual field damage, the method comprising: providing a first stimulus to the patient via a stimulus delivery device associated with the apparatus; receiving a response to the first stimulus from the patient via the stimulus delivery device; if the response is correct, analyzing the patient's head movements in response to the first stimulus; identifying the preferred retinal site based on the analyzed results; Including, The preferred retinal site is a specific area in the peripheral visual field of the patient where the patient recognizes objects, and is set as a target for training at least one of the patient's visual acuity and visual perception ability, and a second stimulus is provided; The first stimulus includes a behavioral task that requires a judgement as to whether an orientation displayed at the center of a screen of the stimulus providing device is horizontal or vertical in order to search the preferred retinal site; The second stimulus is provided to the preferred retinal area capable of object recognition after the first stimulus, and includes a training task using collinearly arranged target stimuli and peripheral stimuli. method.

2. The step of providing a first stimulus comprises: providing the first stimulus repeatedly until a predefined condition is met; The step of receiving the response includes:

2. The method of claim 1, further comprising receiving a plurality of responses to each of the repeatedly provided plurality of first stimuli.

3. The step of analyzing the patient's head movement comprises: The method according to claim 2, characterized in that only correct responses among the plurality of responses are classified into one or more clusters, and the preferred retinal site of the patient is predicted based on the results classified into the one or more clusters.

4. The step of identifying the preferred retinal site comprises: The method of claim 3, further comprising identifying the patient's preferred retinal site through a principal component analysis of the one cluster.

5. A method for training a preferred retinal site of a patient with visual field damage, the method comprising: performing training related to central fixation of the patient; conducting training associated with strengthening the patient's preferred retinal location; Including, The preferred retinal site is a specific area in the peripheral visual field of the patient where the patient recognizes objects, and is identified by a search method that analyzes the patient's head movement due to a first stimulus provided to the patient through a screen of a stimulus providing device linked to the device, and is set as a target for training at least one of the patient's visual acuity and visual perception ability; The first stimulus includes a behavioral task that requires a judgement as to whether an orientation displayed at the center of the screen is horizontal or vertical in order to search the preferred retinal site; The step of performing training related to strengthening the preferred retinal site includes: providing a second stimulus to the preferred retinal region capable of perceiving an object through the stimulus providing device after the first stimulus, and requesting the patient to detect the second stimulus; The second stimulus comprises a training task utilizing a collinear arrangement of target and surround stimuli.

6. The step of performing training related to central fixation includes:

6. The method of claim 5, further comprising displaying a diagonal line across the patient's visual field through the stimulus delivery device and requesting the patient to fixate on a predicted intersection point of the diagonal line.

7. A method for searching and training a preferred retinal site of a patient with visual field damage, the method being carried out by the device, providing a first stimulus to the patient via a stimulus delivery device associated with the apparatus; receiving a response to the first stimulus from the patient via the stimulus delivery device; if the response is correct, analyzing the patient's head movements in response to the first stimulus; identifying the preferred retinal site based on the analyzed results; performing training related to central fixation of the patient; conducting training associated with strengthening the patient's preferred retinal location; Including, The preferred retinal site is a specific area in the peripheral visual field of the patient where the patient recognizes objects, and is set as a target for training at least one of the patient's visual acuity and visual perception ability; The first stimulus includes a behavioral task that requires a judgement as to whether an orientation displayed at the center of a screen of the stimulus providing device is horizontal or vertical in order to search the preferred retinal site; The step of performing training related to strengthening the preferred retinal site includes: providing a second stimulus to the preferred retinal region capable of perceiving an object through the stimulus providing device after the first stimulus, and requesting the patient to detect the second stimulus; The second stimulus comprises a training task utilizing a collinear arrangement of target and surround stimuli.