Hydrogen peroxide aqueous solution for disinfection

Abstract

To provide a hydrogen peroxide aqueous solution for disinfection, which is used in the form of mist or vapor, leaves little residue on a spray nozzle, and enables easy residue removal by rinsing with water.SOLUTION: One embodiment of the present invention pertains to a hydrogen peroxide aqueous solution for disinfection, which is used in the form of mist or vapor, and which comprises hydrogen peroxide, 2-8 ppm of orthophosphoric acid or phosphonic acid, 10-500 ppb of aluminum, and sulfate ions, wherein the amount of sulfate ions is at least 10 times and at most 20 times the amount of aluminum, in terms of mass ratio.SELECTED DRAWING: None

Description

[Technical field]

[0001] The present invention relates to an aqueous hydrogen peroxide solution for sterilization, which is used as a mist or steam. The present invention is also characterized in that the aqueous hydrogen peroxide solution is brought into contact with the object as a mist or vapor. It also relates to a method for sterilizing an object. [Background technology]

[0002] Aqueous solutions containing hydrogen peroxide are used as various disinfectants. The technology of sterilizing objects by contacting them with water or steam is known as the clean room technology for the electronics industry. It is used for sterilizing rooms and sterilizing PET bottles before filling them with beverages. Combined with the widespread use of PET bottles, the demand for hydrogen peroxide solution used for aseptic filling has increased. The performance requirements are becoming higher. In other words, hydrogen peroxide and water need to have less residue when evaporated. There is an increasing demand for chemicals that are highly stable at high temperatures and in metal storage containers.

[0003] When using an aqueous solution containing hydrogen peroxide for aseptic filling, boil the aqueous solution in an evaporator. A method is known in which hydrogen peroxide gas is vaporized by heating it above the sterilization temperature and then sprayed with air to sterilize the container. However, in this method, the hydrogen peroxide solution is added Some of the stabilizer adheres to the spray nozzle and evaporator, blocking the piping and causing sterility. There was a problem that hindered stable operation of the filling device.

[0004] In addition, if the stabilizing effect of the stabilizer is insufficient, the stability may be reduced when stored in a metal container such as stainless steel. There are problems that cannot be maintained.

[0005] To date, hydrogen peroxide has been used as a means of solving the above-mentioned clogging problem and the stability of hydrogen peroxide. It has been proposed to reduce the amount of stabilizer added to the aqueous solution. For example, Patent Document 2 In order to reduce the drying residue and improve the stability of hydrogen peroxide, aminomethylene phosphonic acid is used. Methods for securing it have been reported. [Prior art documents] [Patent documents]

[0006] [Patent Document 1] Japanese Patent Application Publication No. 11-47242 [Patent Document 2] JP 2013-028643 A Summary of the Invention [Problem to be solved by the invention]

[0007] As mentioned above, there have been several proposals to solve the blockage problem and stability problem. Even if the amount of stabilizer added to the hydrogen peroxide solution is reduced to prevent clogging, the spray nozzle and steam The deposits remaining on the generator cannot be completely removed, and the phosphonic acid deposits are difficult to dissolve. Therefore, the problem of blocking the piping and impeding the stable operation of the aseptic filling equipment has not been completely solved. There was a possibility that it had not been resolved.

[0008] Furthermore, recent research by the inventors has revealed that hydrogen peroxide is added as a stabilizer to the aqueous hydrogen peroxide solution. The phosphoric acid and chelating agents used in the tanks leach trace amounts of metals, which then dissolve in hydrogen peroxide. It has become clear that the stability of the material decreases if a large amount of stabilizer is used. However, further improvements are required because the aforementioned spray nozzle blockage and other operational impediments are likely to occur. It is essential.

[0009] The object of the present invention is to reduce the adhesion of residue to the spray nozzle and to make it easy to remove the residue by washing with water. The object of the present invention is to provide an aqueous hydrogen peroxide solution for sterilization, which can be used as a mist or steam. [Means for solving the problem]

[0010] As a result of intensive research into this problem, the present inventors have found that hydrogen peroxide, orthophosphoric acid, or phosphazene Contains sulfonic acid, aluminum, and sulfate ions, and the aluminum and sulfate ion content The aqueous solution having a ratio of the above in a specific range improves the stability of hydrogen peroxide and is suitable for use in a spray nozzle and a vaporizer. The amount of residual stabilizer in the hydrogen peroxide solution that remains on the surface of the substrate is reduced, and the residue is washed away with water. The inventors have found that this makes it possible to easily remove the adhesive layer, thereby arriving at the present invention.

[0011] That is, the present invention is as follows. [1] A hydrogen peroxide solution for sterilization used as a mist or steam, Hydrogen peroxide, Orthophosphoric acid or phosphonic acid, not less than 2 ppm and not more than 8 ppm; Aluminum above 10ppb and below 500ppb; Sulfate ions and The content of the sulfate ions is 10 times or more by mass relative to the content of the aluminum, 0 times or less, in aqueous solution. [2] The concentration of the hydrogen peroxide is 20% by mass or more and 45% by mass or less. solution. [3] The aqueous solution according to [1] or [2], having an evaporation residue amount of 10 ppm or less. [4] In the evaporator adhesion test, the water washing removal rate is 40% or more, and it is one of [1] to [3]. The aqueous solution described. [5] Orthophosphate not less than 2 ppm and not more than 5 ppm; Any of [1] to [4] containing aluminum of 50 ppb or more and 250 ppb or less. 2. An aqueous solution according to any one of claims 1 to 11. [6] Any of [1] to [5] for use in container and packaging material sterilization, instrument sterilization, or space sterilization. 2. An aqueous solution according to any one of claims 1 to 11. [7] The aqueous solution according to any one of [1] to [6] is brought into contact with a target object as a mist or vapor. A method for sterilizing an object, comprising: [8] The sterilization method according to [7], wherein the mist or steam has a temperature of 30°C to 250°C. [9] The mist or vapor is mixed with a gas to form a gaseous fluid, which is then brought into contact with an object. [7] The sterilization method described.

[10] The gas is at least one selected from the group consisting of air, nitrogen, oxygen, and ozone. The sterilization method described in [9].

[11] The object is a packaging container, a food processing machine, a plastic bottle, a plastic bottle preform, or an experimental device. The equipment is a device, medical device, sanitary device, cooking device, or food, as described in any of [7] to

[10] . Sterilization method.

[12] The sterilization method according to any one of [7] to

[10] , wherein the target is a space.

[13] The space may be an automobile or electronics industry clean room, a living space, a medical space, a kitchen, a cooking The sterilization method according to

[12] , wherein the sterilization target is a storage facility, a vehicle, or an aircraft. Effect of the Invention

[0012] The present invention improves the stability of hydrogen peroxide and reduces the amount of hydrogen peroxide remaining on the spray nozzle and vaporizer. Reduces deposits from stabilizers in hydrogen peroxide aqueous solution, and the residue is easily removed by washing with water. It is possible. [Brief description of the drawings]

[0013] [Figure 1] 1 is a graph showing the relationship between the mass ratio of sulfate ion content to aluminum content and residue water washability. [Diagram 2] 1 is a graph showing the relationship between the total amount of stabilizer and stability. [Diagram 3] 1 is a graph showing the relationship between aluminum content and stability. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0014] The present invention will be described in detail below.

[0015] 1. Aqueous hydrogen peroxide solution for sterilization, used as mist or steam The aqueous hydrogen peroxide solution for sterilization used as the mist or vapor of the present invention (referred to herein as "a hydrogen peroxide aqueous solution for sterilization") The aqueous hydrogen peroxide solution of the present invention is a solution of hydrogen peroxide and orthophosphoric acid or The hydrogen peroxide aqueous solution of the present invention further comprises phosphonic acid, aluminum, and sulfate ions. is used as an additive to facilitate the washing off of evaporation residue adhering to spray nozzles, evaporators, etc. Other acids and / or salts may also be included.

[0016] The concentration of hydrogen peroxide in the hydrogen peroxide solution of the present invention is 20% by mass or more, preferably 25% by mass or more. The higher the concentration, the higher the sterilization effect. The concentration of hydrogen peroxide in the hydrogen peroxide solution of the present invention is preferably 45% by mass or less. The preferred concentration range is from 25% by mass to 40% by mass.

[0017] The hydrogen peroxide solution of the present invention is orthophosphoric acid (chemical formula H3PO4, simply called "phosphoric acid"). (also referred to as "phosphonic acid"), the content of which is 2 ppm or more and 8 ppm or less by mass. The lower limit of the content is preferably 3 ppm, the upper limit is preferably 6 ppm, More preferably, the content of orthophosphoric acid or phosphonic acid is within this range. This stabilizes hydrogen peroxide and reduces the amount of evaporation residue that adheres to the evaporator and nozzle. The amount of orthophosphoric acid is suppressed. The content of orthophosphoric acid can be measured by a known method, for example, It can be measured by ion chromatography using the Dionex DX-500. do.

[0018] The orthophosphoric acid used in the present invention is not particularly limited, and is commercially available from Goto Chemical Industry Co., Ltd. Phosphoric acid (concentration: 85%), which has been used for a long time, can be used. It is preferable to use additives designated under the Food Sanitation Act. The orthophosphoric acid used in the present invention may be added to the aqueous solution in the form of a salt of orthophosphoric acid. Examples of such salts include potassium dihydrogen phosphate, sodium dihydrogen phosphate, dihydrogen phosphate, Dihydrogen phosphates such as ammonium hydrogen, dipotassium hydrogen phosphate, and disodium hydrogen phosphate , hydrogen phosphates such as diammonium hydrogen phosphate, tripotassium phosphate, trisodium phosphate and the like phosphates.

[0019] The phosphonic acid used in the present invention is not particularly limited, but is preferably an organic phosphonic acid. Such organic phosphonic acids include aminomethylphosphonic acid, hydroxyethylphosphonic acid, Aminotrimethylenephosphonic acid, ethylenediaminetetramethylenephosphonic acid Sulfonic acid, diethylenetriamine pentamethylene phosphonic acid, hexamethylenediamine tetra tetramethylene phosphonic acid, bishexamethylenetriaminepentamethylene phosphonic acid, and propylenediaminetetramethylenephosphonic acid. The organic phosphonic acid may be added to the aqueous solution in the form of a salt.

[0020] The aqueous hydrogen peroxide solution of the present invention has an aluminum content of 10 ppb or more and 500 ppb or less by mass. The lower limit of the aluminum content is preferably 50 ppb, and more preferably 50 ppb. Preferably, it is 100 ppb, and the upper limit is preferably 350 ppb, more preferably The aluminum content in the hydrogen peroxide solution is, for example, high iCAP 6000 (Thermo Fischer) The aluminum content can be measured using a fluorine-based fluoride (SHER SCIENTIFIC). When the amount is within the above range, the effect of stabilizing hydrogen peroxide is obtained, and the hydrogen peroxide adheres to the evaporator and the spray nozzle. The amount of evaporation residue is suppressed.

[0021] The aluminum contained in the aqueous hydrogen peroxide solution of the present invention is added to the aqueous solution in the form of a salt. Specific examples of such aluminum salts include potassium aluminum sulfate, Aluminum nitrate, aluminum sulfate, aluminum ammonium sulfate, and aluminum oxalate Of these, potassium aluminum sulfate is particularly preferred. The potassium aluminum sulfate preferably used in the present invention is a hydrate such as the dodecahydrate. Alternatively, the aluminum may be prepared by dissolving pure aluminum or an aluminum alloy in hydrogen peroxide. The aluminum salt may be added by contacting it with an aqueous solution. It is preferable to use additives designated by the Sanitation Law.

[0022] The aqueous hydrogen peroxide solution of the present invention contains sulfate ions. The sulfate ions are dissolved in the aqueous solution in the form of a salt. Examples of sulfates that may be added include potassium aluminum sulfate. , aluminum sulfate, aluminum ammonium sulfate, and sodium sulfate. However, it is not limited to these. In particular, sulfates are specified by the Food Sanitation Law. It is preferable to use additives designated as such. The content of sulfate ions is preferably Or, on a mass basis, it is 100 ppb to 10,000 ppb.

[0023] In the aqueous hydrogen peroxide solution of the present invention, the content of sulfate ions is The mass ratio is 10 times or more, preferably 11 times or more, more preferably 12 times or more, and 0 times or less, preferably 19 times or less, more preferably 18 times or less. By having the mass ratio of the content of minium in this range, the stability of hydrogen peroxide is improved and the spraying The amount of deposits from the stabilizer in the hydrogen peroxide solution remaining on the nozzle and evaporator is reduced, The residue can be easily removed by washing with water.

[0024] Heavy metals are known to be the decomposition products of hydrogen peroxide, but industrially produced hydrogen peroxide The decomposition components contained in the aqueous solution are almost limited to Fe, Cr, Ni, and Pd. The hydrogen peroxide solution of the invention has Ni and Pd concentrations of 0.1 ppb or less, and Fe and It is preferable to use an aqueous hydrogen peroxide solution containing Cr at a concentration of 5 ppb or less. Such an aqueous hydrogen peroxide solution can be obtained by a known method, specifically, distillation, ion exchange resin, etc. Methods for removing metal components include using grease, adsorbents, chelating agents, reverse osmosis membranes, etc.

[0025] The aqueous hydrogen peroxide solution of the present invention may be used in combination with other known aqueous hydrogen peroxide solutions as long as the effects of the present invention are not impaired. For example, by using a required amount of an inorganic phosphate stabilizer in combination, It is also possible to further improve stability. Specific examples include sodium hydrogen pyrophosphate, pyrroline and pyrophosphates such as sodium pyrophosphate. In addition, the inorganic phosphate stabilizer is specified by the Food Sanitation Law. It is preferable to use additives designated as such. The drugs include tripotassium phosphate, tricalcium phosphate, trimagnesium phosphate, and phosphoric acid water. Diammonium phosphate, ammonium dihydrogen phosphate, dipotassium hydrogen phosphate, potassium dihydrogen phosphate sodium, monobasic calcium phosphate, dibasic calcium phosphate, disodium hydrogen phosphate, Examples include sodium dihydrogen phosphate, magnesium monohydrogen phosphate, and sodium triphosphate. can be done.

[0026] The total amount of stabilizers in the aqueous hydrogen peroxide solution of the present invention is 2,500 ppb to 7,000 ppb. b, and more preferably 3,000 ppb to 6,000 ppb. stomach.

[0027] In the present invention, other features that improve the water washability of evaporation residues adhering to nozzles, evaporators, etc. The acid and / or salt of L-aminobutyric acid may be selected from the list of additives designated by the Food Sanitation Law. Corbic acid and / or its salts, ethylenediaminetetraacetate, citric acid and / or its salts , gluconic acid and / or its salts, L-glutamic acid and / or its salts, silicates, nitrates , carbonates, pyrophosphates, and sulfates are preferred, with sulfates being particularly preferred.

[0028] The aqueous hydrogen peroxide solution of the present invention preferably has an evaporation residue amount of 10 ppm or less. It is more preferable that the amount of evaporation residue in the hydrogen peroxide solution is less than ppm. It can be measured by the method described in .

[0029] The aqueous hydrogen peroxide solution of the present invention has a water washing removal rate of 40% or more in an evaporator adhesion test. It is preferable that the adhesion rate is 50% or more, and more preferable that the adhesion rate is 50% or more. will be described later in the Examples.

[0030] The aqueous hydrogen peroxide solution of the present invention is used for sterilization as a mist or steam. The method for vaporizing the aqueous hydrogen peroxide solution to generate mist or steam is not particularly limited. The details will be described later in this specification.

[0031] The uses of the aqueous hydrogen peroxide solution of the present invention are not particularly limited, but include sterilization of container packaging materials, sterilization of instruments, etc. It is preferably used for sterilizing bacteria or spaces.

[0032] 2. Method of sterilizing the object The sterilization method of the present invention comprises contacting an object with the aqueous hydrogen peroxide solution of the present invention in the form of mist or vapor. The present invention relates to a method for sterilizing an object, the method comprising the steps of: The details are as stated above.

[0033] The method of vaporizing the hydrogen peroxide aqueous solution to generate mist or steam is not particularly limited, but may be any of the following: For example, ultrasonic or heating methods can be used. The mist or vapor of the aqueous hydrogen chloride solution may be used alone, or may be mixed with another gas to form a gaseous fluid. Preferably, the aqueous hydrogen peroxide solution is heated to above its boiling point in an evaporator. It is vaporized and mixed with another gas to produce a mist or vapor of hydrogen peroxide solution to be used as a gaseous fluid. The device for heating and vaporizing the aqueous hydrogen peroxide solution is not particularly limited, and a known device can be used. By using a mixture of gases, it is possible to more efficiently measure the surface of an object with irregular shapes. The material can be contacted with a mist or vapor of an aqueous hydrogen peroxide solution.

[0034] Specific examples of the gas that may be entrained with the mist or vapor of the hydrogen peroxide aqueous solution include air, nitrogen, and the like. Gases to be mixed include nitrogen, oxygen, and ozone. Air is particularly preferable because it is inexpensive. The temperature is preferably at least room temperature.

[0035] When the mist or vapor of the hydrogen peroxide solution is brought into contact with the object, the entrained gas is also heated. It is more desirable to do so.

[0036] Hydrogen peroxide mist or vapor, or hydrogen peroxide mixed with another gas The temperature of the gaseous fluid such as mist or steam is preferably 30 to 250°C, more preferably The temperature range is preferably 50°C to 200°C, and more preferably 100°C to 150°C. By using this method, sufficient sterilization ability can be obtained and damage to the object to be sterilized by heat can be effectively prevented. It can be stopped.

[0037] The objects include packaging containers, food machinery, PET bottles, PET bottle preforms, and Examples include, but are not limited to, laboratory equipment, medical equipment, sanitary equipment, cooking equipment, food and space. It is not something that can be determined.

[0038] Spaces include clean rooms for automobiles and electronics industries, living spaces, medical spaces, and kitchens. Examples include, but are not limited to, kitchens, vehicles, and aircraft.

[0039] In the present invention, a hydrogen peroxide aqueous solution mist and / or steam generating device is brought into the facility, It can also generate a mist and / or vapor of hydrogen peroxide solution to reduce the number of bacteria in the facility. do.

[0040] Examples of such facilities include toiletry facilities, waste treatment facilities, and livestock sheds. However, the present invention is not limited to these. EXAMPLES

[0041] Next, the present invention will be described in more detail with reference to examples and comparative examples. The present invention is not limited to the above embodiments.

[0042] <Method for evaluating hydrogen peroxide stability and evaporation residue> The stability and evaporation residue of hydrogen peroxide were evaluated according to the method specified in JIS-K1463. .

[0043] <Measurement of Phosphate and Sulfate Ion Concentrations> The concentrations of phosphoric acid and sulfate ions in the hydrogen peroxide solution were measured using an ion chromatograph DX-5 00 (Dionex).

[0044] <Aluminum concentration> The aluminum concentration in the hydrogen peroxide solution was measured using an ICP emission spectrometer iCAP 6000 ( Measurements were performed using a 3D microscope (manufactured by Thermo Fisher Scientific).

[0045] <Evaluation of evaporator adhesion amount and water washability> The simulated evaporator used was a scaled-down simulation based on a known evaporator. Hydrogen peroxide aqueous solution sample with a hydrogen peroxide concentration of 35% was fed at a constant rate while being mixed with air into the simulated evaporator heated to 300 °C for vaporization, and tested for 80 hours. In the case of a hydrogen peroxide concentration of 25%, it was 11 2 hours. The weight of the simulated evaporator after the test was measured, and the weight difference from before the test was taken as the adhesion amount (mg) and used. Further, this was washed with ion-exchanged water, dried, and the weight was measured again, and the weight difference from before the test was taken as the residual amount (mg). From the adhesion amount and the residual amount, the water washing removal rate (%) was calculated based on the following formula and obtained. Water washing removal rate (%) = [1 - {residual amount (mg) / adhesion amount (mg)}] × 100 (Simulated evaporator structure) Material: SUS304L Size: A conical nozzle with a height of 17 mm was attached to the tip of a cylindrical vaporization chamber with a size of 150 mm × 23 mm φ. A conical nozzle with a 2 mm φ hole at the tip was used . (Conditions) Liquid feeding flow rate of hydrogen peroxide aqueous solution sample: 1.25 mL / min Air flow rate: 2.1 L / min Ion-exchanged water flow rate: 500 ml / 1.5 min Gas-fluid temperature at the nozzle opening: 100 - 120 °C

[0046] <SUS immersion test> Two SUS304L test pieces (30 mm × 30 mm × 2 mm) were placed in 300 ml of hydrogen peroxide water sample, and left standing at 45 °C for 24 hours

[0047] <Example 1> Orthophosphoric acid (manufactured by Goto Chemical Co., Ltd., phosphoric acid (concentration 85.0%)) 3 mass ppm and potassium aluminum sulfate (Wako were added to hydrogen peroxide water that was distilled and purified and had its concentration adjusted to 35% with pure water ​1 mass of potassium aluminum sulfate dodecahydrate (concentration 96.5%) manufactured by Junyaku Kogyo Co., Ltd. ppm, sodium sulfate (Wako Pure Chemical Industries, Ltd., sodium sulfate decahydrate (concentration 9 0.5 mass ppm of sulfate ion (9.0%) was added. The sulfate ion / Al ratio at this time was 14. The evaporation residue of this hydrogen peroxide aqueous solution sample was 6 ppm by mass, and the amount of adhesion to the evaporator was 1 The removal rate of the deposits by washing with water was 59%.

[0048] <Example 2-4> The hydrogen peroxide concentration, the amount of potassium aluminum sulfate added, and the amount of sodium sulfate added were The contents of each component were as shown in Table 1. The sulfate ion / Al ratio of these hydrogen peroxide aqueous solution samples was in the range of 10 to 20. The rate of removal of deposits on the evaporator by washing with water was about 60%.

[0049] <Comparative Example 1-5> The hydrogen peroxide concentration, the amount of potassium aluminum sulfate added, and the amount of sodium sulfate added were The contents of each component were as shown in Table 1. The sulfate ion / Al ratio of these hydrogen peroxide aqueous solution samples was in the range of 10 to 20. The amount of adhesion to the evaporator of these hydrogen peroxide aqueous solution samples was worsened in some samples. The removal rate of the stabilizer was significantly decreased in all cases. When phosphoric acid was used alone, there was a significant increase in the amount of adhesion and a significant decrease in stability after immersion in SUS.

[0050] <Comparative Example 6> In Comparative Example 6, the hydrogen peroxide concentration, the amount of potassium aluminum sulfate added, and the amount of sodium sulfate added were also The amount of ammonium added was changed and the same experiment as in Example 1 was carried out. 1. The sulfate ion / Al ratio of the hydrogen peroxide aqueous solution sample of Comparative Example 6 is The content of orthophosphate is in the range of 10 to 20 ppm, but it exceeds 8 ppm. In the case of the sample, both the amount of deposit on the evaporator and the rate of removal by washing with water were deteriorated.

[0051] The results are shown in Table 1 and Figures 1 to 3. [Table 1]

[0052] From the above results, even if the total content of Al and the total content of stabilizers are small, the content of sulfate ions is The amount of aluminum is 10 times or more and 20 times or less by mass ratio. While maintaining the stability of hydrogen peroxide, it is possible to reduce the amount of adhesion and increase the rate of removal by washing with water. This can be seen (for example, Example 1 and Comparative Example 2). [Industrial Applicability]

[0053] The present invention improves the stability of hydrogen peroxide in an aqueous hydrogen peroxide solution, and reduces the need for a spray nozzle or evaporator. The product reduces the amount of residue from the stabilizer in the hydrogen peroxide solution that remains on the vessel, etc., and prevents the residue from becoming water-soluble. It can be easily removed by washing, so it does not clog narrow pipes such as nozzles. This enables stable operation of the aseptic filling equipment.

Claims

1. A hydrogen peroxide solution for sterilization used as a mist or steam, Hydrogen peroxide, Orthophosphoric acid or phosphonic acid having 2 ppm or more and 8 ppm or less; Aluminum not less than 10 ppb and not more than 500 ppb; Sulfate ions and The content of the sulfate ions is 10 times or more by mass ratio relative to the content of the aluminum, 0 times or less, in aqueous solution.

2. 2. The method according to claim 1, wherein the concentration of the hydrogen peroxide is 20% by mass or more and 45% by mass or less. Aqueous solution.

3. 3. The aqueous solution according to claim 1, wherein the amount of evaporation residue is 10 ppm or less.

4. Any one of claims 1 to 3, wherein the water-washing removal rate in an evaporator adhesion test is 40% or more.

2. The aqueous solution according to claim 1 .

5. Orthophosphoric acid having 2 ppm or more and 5 ppm or less; Any one of claims 1 to 4, further comprising 50 ppb or more and 250 ppb or less of aluminum.

13. The aqueous solution according to claim 1.

6. Any one of claims 1 to 5 for use in container packaging material sterilization, instrument sterilization, or space sterilization.

13. The aqueous solution according to claim 1.

7. The aqueous solution according to any one of claims 1 to 6 is brought into contact with an object as a mist or vapor. A method for sterilizing an object, comprising:

8. The sterilization method according to claim 7, wherein the mist or steam has a temperature of 30°C to 250°C.

9. The mist or vapor is mixed with a gas to form a gaseous fluid, which is then contacted with the object as claimed in claim 7. The sterilization method described in claim 1.

10. The gas is at least one selected from the group consisting of air, nitrogen, oxygen, and ozone. The sterilization method according to claim 9.

11. The object is a packaging container, a food processing machine, a plastic bottle, a plastic bottle preform, or an experimental device. The device according to any one of claims 7 to 10, which is a device, a medical device, a sanitary device, a cooking device or a food. The sterilization method described above.

12. The sterilization method according to any one of claims 7 to 10, wherein the object is a space.

13. The space may be an automobile or electronics industry clean room, a living space, a medical space, a kitchen, a cooking The sterilization method according to claim 12, wherein the sterilization target is a workplace, a vehicle or an aircraft.

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