Program, information processing device and information processing method

Abstract

To make presentation of an examination result efficient.SOLUTION: A program according to one embodiment of the present disclosure is configured to make a computer function as: acquisition means of acquiring a first examination result and second examination result about a body of an object person, in which the first examination includes genetic screening, and the second examination includes any of a blood examination, urinalysis and at least a part of examinations about a comprehensive medical examination,; generation means of generating coupled risk information indicative of a risk of prescribed diseases of the object person on the basis of the first examination result and the second examination result; and risk information output means of outputting the coupled risk information.SELECTED DRAWING: Figure 1

Description

Technical Field

[0001] The present disclosure relates to a program, an information processing apparatus, and an information processing method.

Background Art

[0002] Conventionally, technologies related to examinations in medical institutions are known. For example, Patent Document 1 describes a technology for avoiding duplicate examinations in multiple medical institutions in a system such as regional medical cooperation.

Prior Art Documents

Patent Documents

[0003]

Patent Document 1

Summary of the Invention

Problems to be Solved by the Invention

[0004] In the technology described in Patent Document 1, the presentation of examination results cannot be sufficiently streamlined. The present disclosure aims to streamline the presentation of examination results.

Means for Solving the Problems

[0005] A program according to an aspect of the present disclosure causes a computer to function as an acquisition unit that acquires the results of a first examination and a second examination regarding a subject's body, where the first examination includes a genetic test, and the second examination includes at least one of a blood test, a urine test, and at least a part of an examination related to a general medical check-up; a generation unit that generates combined risk information indicating the risk of a predetermined disease of the subject based on the results of the first examination and the second examination; and a risk information output unit that outputs the combined risk information.

[0006] An information processing apparatus according to another aspect of the present disclosure includes an acquisition unit that acquires the results of a first examination and a second examination regarding the body of a subject, where the first examination includes a genetic examination, and the second examination includes any one of a blood test, a urine test, and a comprehensive medical checkup; a generation unit that generates combined risk information indicating the risk of a predetermined disease of the subject based on the results of the first examination and the second examination; and a risk information output unit that outputs the combined risk information.

[0007] An information processing method according to another aspect of the present disclosure includes steps of causing a computer to acquire the results of a first examination and a second examination regarding the body of a subject, where the first examination includes a genetic examination, and the second examination includes any one of a blood test, a urine test, and a comprehensive medical checkup; generate combined risk information indicating the risk of a predetermined disease of the subject based on the results of the first examination and the second examination; and output the combined risk information.

Advantages of the Invention

[0008] According to the present disclosure, the presentation of examination results can be made more efficient.

Brief Description of the Drawings

[0009]

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Embodiments for Carrying Out the Invention

[0010] <1. Overview> For the examination of diseases such as cancer, there are multiple methods, for example, genetic testing, blood testing, urine testing, and general medical check-ups. Conventionally, these tests have been independent of each other. In order to analyze multiple test results, the person undergoing the tests had to undergo each test separately and analyze the test results by themselves. In particular, regarding genetic testing, generally the test results do not change over time (that is, the test results are determined by the innate genes), so it is usually conducted separately from other tests such as blood testing, urine testing, and general medical check-ups, whose test results can change over time.

[0011] On the other hand, according to the information processing apparatus 2 according to the present disclosure, the presentation of inspection results can be made more efficient. FIG. 1 is a diagram showing an outline of the operation of the information processing apparatus 2 according to the present disclosure. First, the information processing apparatus 2 acquires the results of a genetic test for a disease such as cancer performed by the subject (S1). Next, the information processing apparatus 2 acquires the results of supplementary tests such as a blood test, a urine test, and a general medical check-up for the disease performed by the subject (S2). Next, the information processing apparatus 2 generates combined risk information indicating the risk of the disease based on the results of the genetic test and the results of the supplementary tests, and presents it to the subject (S3). Note that the urine test in the present disclosure may be for the purpose of cancer screening.

[0012] According to the information processing apparatus 2, information obtained by comprehensively analyzing the results of the genetic test and the results of the supplementary tests can be presented to the subject. Further, according to the information processing apparatus 2, it is possible to achieve both the comprehensiveness of the genetic test and the continuous disease prevention by the supplementary test.

[0013] Hereinafter, the genetic test and the supplementary test will be described on the assumption that they are for investigating the risk of cancer. That is, the information processing apparatus 2 will be described as outputting the cancer risk of the subject based on the results of the genetic test and the results of the supplementary tests.

[0014] <2. Configuration> With reference to FIGS. 2-3, an example of the configuration of the system 1 will be described.

[0015] FIG. 2 is a diagram showing an example of the overall configuration of the system 1. The system 1 includes an information processing apparatus 2, a subject terminal device 3a, a counselor terminal device 3b, a genetic testing institution device 4a, an auxiliary testing institution device 4b, and a communication network 5. Hereinafter, when the subject terminal device 3a and the counselor terminal device 3b are not particularly distinguished, these are collectively referred to as the "terminal device 3". Also, when the genetic testing institution device 4a and the auxiliary testing institution device 4b are not particularly distinguished, these are collectively referred to as the "testing institution device 4". The information processing apparatus 2, the terminal device 3, and the testing institution device 4 are configured to be able to communicate with each other via the communication network 5.

[0016] [Terminal device 3] The terminal device 3 is a device such as a personal computer, a smartphone, and a tablet terminal. The terminal device 3 is provided with an input device (for example, a keyboard, a mouse, a button, a touch panel, a camera, and a microphone, etc.), and can receive the input of various information through the input device. Further, the terminal device 3 is provided with an output device (for example, a display and a speaker, etc.), and can output various information through the output device.

[0017] The subject terminal device 3a is a device used by a subject (hereinafter simply referred to as "subject") of genetic testing and auxiliary testing. The counselor terminal device 3b is a device used by a counselor who conducts health consultations with the subject. The counselor is, for example, a doctor, a nurse, a health care worker, and a registered dietitian, etc.

[0018] [Inspection institution device 4] The inspection institution device 4 is a device provided in an institution that conducts inspections on subjects and holds the results. The inspection institution device 4 may be a server device included in a predetermined medical system, or may be a terminal device used by medical staff such as doctors.

[0019] The genetic testing institution device 4a is a device provided in an institution that conducts genetic testing and holds the results. The auxiliary testing institution device 4b is a device provided in an institution that conducts at least one of blood tests, urine tests, comprehensive medical check-ups, etc. as auxiliary tests and holds the results. The auxiliary testing institution device 4b can also be referred to as a blood test institution device, a urine test institution device, or a comprehensive medical check-up institution device.

[0020] [Information processing device 2] The information processing device 2 is a device that acquires the results of genetic testing and auxiliary testing of a subject, and generates and outputs combined risk information based on these. The information processing device 2 can also be said to be a server device when the terminal device 3 and the inspection institution device 4 are client devices.

[0021] FIG. 3 is a diagram showing an example of the configuration of the information processing apparatus 2. The information processing apparatus 2 includes a control unit 10, a storage unit 12, a network interface unit 14, and a bus 16. The control unit 10, the storage unit 12, and the network interface unit 14 are electrically connected via the bus 16.

[0022] (Control Unit 10) The control unit 10 functions as an acquisition unit 100, a generation unit 102, an output unit 104, and an analysis unit 106 by executing various programs stored in the storage unit 12.

[0023] - Acquisition Unit 100 - The acquisition unit 100 acquires the results of genetic tests and auxiliary tests related to the body of the subject. The acquisition unit 100 may acquire the test results uploaded from the subject terminal device 3a, or may acquire the test results stored in the testing institution device 4. The acquisition unit 100 may acquire the test results in the form of an image file (e.g., JPEG file, etc.), may acquire the test results in the form of a document file (e.g., PDF file, etc.), or may acquire the test results in the form of a text file (e.g., JSON file, etc.). The acquisition unit 100 may acquire the test results input to the subject terminal device 3a or the testing institution device 4 via, for example, a predetermined web page.

[0024] The results of the genetic test include, for example, information such as the cancer incidence magnification of the subject compared to the average, the cancer incidence rate of the subject, and genes related to the cancer incidence of the subject.

[0025] The results of the blood test include, for example, information on the amounts of various components contained in the subject's blood, the reference values of the amounts of various components, and the amounts of various components contained in the subject's blood compared to the reference values. The various components include, for example, hemoglobin, blood glucose level, blood lipids, components indicating liver function (GOT, GPT, γ-GTP), components indicating kidney function (creatinine, urea nitrogen), uric acid level, etc.

[0026] The results of the urine test include, for example, information regarding the amounts of porphyrin and 8-OHdG (8-hydroxy-2’-deoxyguanosine) contained in the urine of the subject. Note that the amount of porphyrin indicates the state of the metabolic function of cells. Also, the amount of 8-OHdG indicates the state of oxidation (i.e., aging) of cells.

[0027] The results of the comprehensive medical checkup include, for example, the results of blood tests, urine tests, stool tests, abdominal ultrasound tests, electrocardiogram tests, chest X-ray tests, and the like.

[0028] In the present disclosure, "acquiring information" includes making the information in a state processable by the control unit 10. Acquiring information may be any of receiving the information from another device, reading the information from the storage unit 12, and obtaining the information as a result of processing other information by the control unit 10. The acquisition means 100 for acquiring various information can also be said to be an input means for inputting various information to the control unit 10.

[0029] ― Generation means 102 ― Based on the results of the genetic test and the results of the auxiliary test, the generation means 102 generates combined risk information indicating the cancer risk of the subject.

[0030] ~ Gene risk information and auxiliary risk information ~ In one embodiment, the generation means 102 further generates risk information (hereinafter referred to as "gene risk information") indicating the cancer risk based on the results of the genetic test. Also, in one embodiment, the generation means 102 further generates risk information (hereinafter referred to as "auxiliary risk information") indicating the cancer risk based on the results of the auxiliary test. The gene risk information can also be referred to as first risk information. Also, the auxiliary risk information can also be referred to as second risk information.

[0031] ~ Risk value ~ In one embodiment, the gene risk information includes a risk value (hereinafter referred to as "gene risk value") calculated based on the results of a gene test. Also, in one embodiment, the auxiliary risk information includes a risk value (hereinafter referred to as "auxiliary risk value") calculated based on the results of an auxiliary test. In this case, the combined risk information includes a combined risk value calculated based on the gene risk value and the auxiliary risk value. The gene risk value can also be referred to as the first risk value. Also, the auxiliary risk value can also be referred to as the second risk value.

[0032] ~Evaluation, Comment, and Indicator~ In one embodiment, the auxiliary risk information includes an evaluation ranking the results of the auxiliary test, a comment determined based on the results of the auxiliary test, and an indicator corresponding to the comment. The evaluation ranking the results of the auxiliary test is expressed, for example, by alphabets such as "A", "B", and "C", the presence or absence of abnormality such as "abnormal" and "normal", and the next action to be taken such as "no action required", "observation required", and "precision examination required". The comment is input, for example, by a doctor who has confirmed the test results. The indicator corresponding to the comment is determined by the analysis means 106 described later.

[0033] In one embodiment, the gene risk information includes an evaluation ranking the results of the gene test, a comment determined based on the results of the gene test, and an indicator corresponding to the comment. Similarly, in one embodiment, the combined risk information includes an evaluation ranking the integrated results of the gene test and the auxiliary test, a comment determined based on the integrated results of the gene test and the auxiliary test, and an indicator corresponding to the comment.

[0034] ~Risk Determination Method~ In one embodiment, the cancer risk included in the examination result is determined based on the onset risk of cancer in the subject and the risk of cancer progression. For example, the risk of colorectal cancer in the subject is determined based on the onset risk of colorectal cancer in the subject and the risk of colorectal cancer progression. Additionally, for example, the risk of gastric cancer in the subject is determined based on the onset risk of gastric cancer in the subject and the risk of gastric cancer progression. An example of the onset risk is the incidence rate. The risk of progression is, for example, the mortality rate, the progression rate, the 5-year survival rate, the severity of the prognosis, the average length of hospitalization, the difficulty of treatment, and the severity of symptoms, etc.

[0035] In one embodiment, the onset risk of cancer in the subject is determined based on the cancer prevalence rate in a predetermined population (for example, a population of Japanese people of the same gender and the same age group as the subject) and the susceptibility of the subject to cancer onset determined based on at least one of the results of genetic testing and the results of supplementary examinations. For example, the onset risk of colorectal cancer in the subject is determined based on the colorectal cancer prevalence rate in a population of Japanese people of the same gender and the same age group as the subject and the susceptibility of the subject to colorectal cancer onset determined based on the results of genetic testing and the results of supplementary examinations.

[0036] In the present disclosure, the "cancer prevalence rate" is described as a value obtained by dividing the number of cancer patients who occurred in a predetermined population within a predetermined period by the population of the predetermined population.

[0037] Also, in the present disclosure, the "susceptibility of the subject to cancer onset" is described as indicating the susceptibility of the subject to cancer onset when compared with the average of a predetermined population. The susceptibility of the subject to cancer onset can also be referred to as the onset multiple.

[0038] Also, in the present disclosure, "generating information" includes making the information in a state processable by the control unit 10 as a result of a predetermined process.

[0039] ―Output means 104― Output means 104 outputs various types of information. In one embodiment, output means 104 includes risk information output means 104a and notification output means 104b.

[0040] ~Risk information output means 104a~ Risk information output means 104a outputs combined risk information generated based on the results of genetic testing and the results of supplementary testing. In one embodiment, risk information output means 104a further outputs gene risk information generated based on the results of genetic testing. In one embodiment, risk information output means 104a further outputs supplementary risk information generated based on the results of supplementary testing.

[0041] In one embodiment, risk information output means 104a outputs information indicating the relationship between the combined risk information, the gene risk information, and the supplementary risk information. An example of the information indicating the relationship is information showing the combined risk information, the gene risk information, and the supplementary risk information in a comparable manner. Another example of the information indicating the relationship is a graph showing the relationship between the combined risk value, the gene risk value, and the supplementary risk value.

[0042] In one embodiment, risk information output means 104a outputs a plurality of pieces of combined risk information. For example, risk information output means 104a outputs combined risk information indicating the risk of colorectal cancer of the subject and combined risk information indicating the risk of gastric cancer of the subject. Risk information output means 104a can also output combined risk information for each of a plurality of cancer types.

[0043] ~Notification output means 104b~ Notification output means 104b outputs a notification prompting the subject to perform a supplementary test based on the fact that acquisition means 100 has acquired the results of genetic testing. For example, notification output means 104b may output a notification to the effect of "Please perform a supplementary test" to the subject terminal device 3a, or may output a notification to the effect of "Please prompt the subject to perform a supplementary test" to the counselor terminal device 3b.

[0044] In one embodiment, the notification output means 104b outputs a notification prompting the subject to conduct a health consultation based on the acquisition means 100 further acquiring the result of the supplementary examination. The notification output means 104b may output, for example, a notification to the subject terminal device 3a to the effect of "Please conduct a health consultation with a counselor", or may output, for example, a notification to the counselor terminal device 3b to the effect of "Please conduct a health consultation with the subject".

[0045] In one embodiment, regardless of whether the acquisition means 100 has acquired the result of the supplementary examination, the notification output means 104b outputs a notification prompting the subject to conduct the supplementary examination at a predetermined time interval. That is, the notification output means 104b periodically reminds the subject to conduct the supplementary examination.

[0046] In the present disclosure, "outputting information" includes at least making the information recognizable to the subject. Outputting information may be either transmitting the information to another device via the communication network 5 or displaying the information on a display device.

[0047] - Analysis means 106- The analysis means 106 determines an index corresponding to the comment by analyzing the comment determined based on the result of the supplementary examination or the genetic test. In one embodiment, the analysis means 106 determines an index based on the comment and keyword information (see FIG. 13 described later) in which the importance of each of one or more keywords included in the comment is associated. In one embodiment, the analysis means 106 determines an index corresponding to the comment by analyzing the comment by natural language processing technology. The index may be expressed by a numerical value, a symbol, a character, a word, a color, etc.

[0048] (Storage unit 12) The storage unit 12 stores various programs executed by the control unit 10. The storage unit 12 also includes a keyword information DB 120 that stores keyword information referred to by the analysis means 106.

[0049] (Network interface unit 14) The network interface unit 14 realizes communication with other devices via the communication network 5.

[0050] <3. Operations> With reference to FIGS. 4-11, an example of the operation of the information processing apparatus 2 and an example of the display screen of the terminal apparatus 3 will be described. Hereinafter, it is assumed that the supplementary examination is a blood test. Also, risk information indicating the risk of cancer based on the results of the blood test is referred to as "blood risk information". The blood risk information includes a "blood risk value", which is a supplementary risk value calculated based on the results of the blood test.

[0051] [Calculation of gene risk value] FIG. 4 is a flowchart showing an example of the operation of the information processing apparatus 2. First, the information processing apparatus 2 acquires the results of the genetic test of the subject from the subject terminal apparatus 3a or the genetic test institution apparatus 4a (S100). Next, the information processing apparatus 2 calculates the gene risk value of the subject based on the acquired results of the genetic test (S102).

[0052] With reference to FIG. 5, an example of the operation in which the information processing apparatus 2 calculates the gene risk value based on the results of the genetic test will be described. In the table of FIG. 5, "r1" to "r3", "A1" to "A3", and "D1" to "D3" are all positive real numbers.

[0053] The table of FIG. 5 indicates that the incidence rates of "colorectal cancer", "stomach cancer", and "lung cancer" of the subject are "r1", "r2", and "r3", respectively. The incidence rates of cancer are included in the results of the genetic test acquired by the information processing apparatus 2. The table of FIG. 5 also indicates that the prevalence rates of "colorectal cancer", "stomach cancer", and "lung cancer" of Japanese people in the same category as the subject are "A1", "A2", and "A3", respectively.

[0054] The information processing apparatus 2 calculates the incidence rate by multiplying the prevalence rate by the morbidity multiple. In this example, the information processing apparatus 2 calculates the incidence rates of "colorectal cancer", "stomach cancer", and "lung cancer" of the subject as "r1 × A1", "r2 × A2", and "r3 × A3", respectively.

[0055] Furthermore, the table in FIG. 5 indicates that the mortality rates of "colorectal cancer", "stomach cancer", and "lung cancer" are "D1", "D2", and "D3", respectively.

[0056] The information processing apparatus 2 calculates the gene risk value by multiplying the incidence rate by the mortality rate. In this example, the information processing apparatus 2 calculates the gene risk values of "colorectal cancer", "stomach cancer", and "lung cancer" of the subject as "r1 × A1 × D1", "r2 × A2 × D2", and "r3 × A3 × D3", respectively. Hereinafter, the calculated gene risk values of "colorectal cancer", "stomach cancer", and "lung cancer" are represented as "GR1", "GR2", and "GR3", respectively. The gene risk value calculated in this way is included in the gene risk information.

[0057] [Calculation of blood risk value] Returning to FIG. 4, next, the information processing apparatus 2 outputs a notification prompting the subject to perform a blood test to the subject terminal device 3a (S104). The subject who has confirmed the notification performs a blood test at the testing institution. Next, the information processing apparatus 2 acquires the result of the subject's blood test from the subject terminal device 3a or the auxiliary testing institution device 4b (S106). The information processing apparatus 2 calculates the blood risk value of the subject based on the acquired blood test result (S108).

[0058] With reference to FIGS. 6-7, an example of the operation in which the information processing apparatus 2 calculates the blood risk value based on the blood test result will be described. In the tables of FIGS. 6-7, "v1" to "v3", "m1" to "m3", "σ1" to "σ3", and "C11" to "C33" are all positive real numbers.

[0059] The table in FIG. 6 shows the results of the blood test of the subject and the degree of deviation of the measured values. The table in FIG. 6 indicates that the measured values of "Item α", "Item β", and "Item γ" in the blood test of the subject are "v1", "v2", and "v3", respectively. The measured values of "Item α", "Item β", and "Item γ" are included in the results of the blood test acquired by the information processing device 2. Further, the table in FIG. 6 indicates that the appropriate values of "Item α", "Item β", and "Item γ" are "m1", "m2", and "m3", respectively, and the differential standards are "σ1", "σ2", and "σ3", respectively. The differential standard is a value that is standardized as the absolute value of the difference between the measured value and the appropriate value.

[0060] The information processing device 2 calculates the degree of deviation based on the measured value, the appropriate value, and the differential standard. The degree of deviation is a value obtained by evaluating the absolute value of the difference between the measured value and the appropriate value based on the differential standard. That is, it can be said that the smaller the degree of deviation, the closer the measured value of the subject is to the appropriate value, and the larger the degree of deviation, the farther the measured value of the subject is from the appropriate value. In this example, it is assumed that the degree of deviation is calculated by inputting the measured value, the appropriate value, and the differential standard to the function "f".

[0061] The function "f" may calculate discrete values as the degree of deviation. For example, if the absolute value of the difference between the measured value "v1" and the appropriate value "m1" is less than "σ1", the information processing device 2 may calculate the degree of deviation of "Item α" as "0". Additionally, for example, if the absolute value of the difference between the measured value "v1" and the appropriate value "m1" is equal to or greater than "σ1" and less than "2×σ1", the information processing device 2 may calculate the degree of deviation of "Item α" as "1". Additionally, for example, if the absolute value of the difference between the measured value "v1" and the appropriate value "m1" is equal to or greater than "2×σ1", the information processing device 2 may calculate the degree of deviation of "Item α" as "2".

[0062] The function "f" may calculate continuous values as the degree of deviation. For example, the information processing device 2 may calculate the degree of deviation by dividing the absolute value of the difference between the measured value and the appropriate value by the differential standard.

[0063] Hereinafter, the degrees of deviation of the calculated "Item α", "Item β", and "Item γ" are represented as "d1", "d2", and "d3", respectively.

[0064] The table in Figure 7 shows the correlation between cancer and the test items of a blood test. The table in Figure 7 shows that, regarding "colorectal cancer", the respective correlations of the "Item α", "Item β", and "Item γ" of the blood test are "C11", "C12", and "C13". Also, the table in Figure 7 shows that, regarding "gastric cancer", the respective correlations of the "Item α", "Item β", and "Item γ" are "C21", "C22", and "C23". Also, the table in Figure 7 shows that, regarding "lung cancer", the respective correlations of the "Item α", "Item β", and "Item γ" are "C31", "C32", and "C33".

[0065] The information processing device 2 calculates a blood risk value of cancer based on the degrees of deviation of the measured values of "Item α", "Item β", and "Item γ", and the correlations between cancer and "Item α", "Item β", and "Item γ".

[0066] Specifically, the information processing device 2 calculates the blood risk value of "colorectal cancer" by the sum of the following (1-1) to (1-3). (1-1) The product of the degree of deviation "d1" of "Item α" and the correlation "C11" between "colorectal cancer" and "Item α" (1-2) The product of the degree of deviation "d2" of "Item β" and the correlation "C12" between "colorectal cancer" and "Item β" (1-3) The product of the degree of deviation "d3" of "Item γ" and the correlation "C13" between "colorectal cancer" and "Item γ"

[0067] Similarly, the information processing device 2 calculates the blood risk value of "gastric cancer" by the sum of the following (2-1) to (2-3). (2-1) The product of the degree of deviation "d1" of "Item α" and the correlation "C21" between "gastric cancer" and "Item α" (2-2) The product of the degree of deviation "d2" of "Item β" and the correlation "C22" between "gastric cancer" and "Item β" (2-3) The product of the deviation degree "d3" of "Item γ" and the correlation "C23" between "stomach cancer" and "Item γ"

[0068] Similarly, the information processing device 2 calculates the blood risk value of "lung cancer" by the sum of the following (3-1) to (3-3). (3-1) The product of the deviation degree "d1" of "Item α" and the correlation "C31" between "lung cancer" and "Item α" (3-2) The product of the deviation degree "d2" of "Item β" and the correlation "C32" between "lung cancer" and "Item β" (3-3) The product of the deviation degree "d3" of "Item γ" and the correlation "C33" between "lung cancer" and "Item γ"

[0069] Hereinafter, the calculated blood risk values of "colon cancer", "stomach cancer" and "lung cancer" are represented as "BR1", "BR2" and "BR3", respectively. The blood risk values calculated in this way are included in the blood risk information. [Calculation of combined risk value] Returning to FIG. 4, next, the information processing device 2 calculates the combined risk value of the subject based on the gene risk value calculated based on the result of the genetic test and the blood risk value calculated based on the result of the blood test (S110).

[0070] Referring to FIG. 8, an example of the operation in which the information processing device 2 calculates the combined risk value will be described. In the table of FIG. 8, "Frc" represents a function that calculates the square root of the sum of the squares of two values (that is, squares each of the two values, calculates the sum thereof, and calculates the square root of the sum).

[0071] As shown in FIG. 8, the information processing apparatus 2 calculates a combined risk value for "colorectal cancer" by taking the square root of the sum of the squares of "GR1", which is the gene risk value for "colorectal cancer", and "BR1", which is the blood risk value for "colorectal cancer". Further, the information processing apparatus 2 calculates a combined risk value for "stomach cancer" by taking the square root of the sum of the squares of "GR2", which is the gene risk value for "stomach cancer", and "BR2", which is the blood risk value for "stomach cancer". Further, the information processing apparatus 2 calculates a combined risk value for "lung cancer" by taking the square root of the sum of the squares of "GR3", which is the gene risk value for "lung cancer", and "BR3", which is the blood risk value for "lung cancer". The combined risk value calculated in this way is included in the combined risk information. Hereinafter, the calculated combined risk values for "colorectal cancer", "stomach cancer", and "lung cancer" are represented as "RSS1", "RSS2", and "RSS3", respectively.

[0072] [Presentation of a graph showing the relationship between risk values] Returning to FIG. 4, the information processing apparatus 2 outputs a notification prompting the implementation of a health consultation to the subject terminal device 3a (S112). Next, the information processing apparatus 2 outputs the gene risk value, the blood risk value, and the combined risk value to the subject terminal device 3a and the counselor terminal device 3b (S114).

[0073] FIG. 9 is a diagram showing an example of a display screen on the subject terminal device 3a that has acquired the gene risk value, the blood risk value, and the combined risk value. The subject and the counselor can conduct a health consultation while referring to such a display screen.

[0074] The example display screen in FIG. 9 includes a message e100, a colorectal cancer risk information display area e102, a stomach cancer risk information display area e104, a lung cancer risk information display area e106, a gene test details confirmation button e108, a blood test details confirmation button e110, a combined risk details confirmation button e112, and a superimposed display button e114.

[0075] The message e100 displays a message for the subject. In this example, it is displayed as "Your cancer risk".

[0076] In the colorectal cancer risk information display area e102, a graph of a two-dimensional coordinate axis showing the relationship between the gene risk value "GR1", the blood risk value "BR1", and the combined risk value "RSS1" regarding "colorectal cancer" of the subject is displayed. Specifically, in the graph of the colorectal cancer risk information display area e102, a mark is attached to the coordinates "GR1, BR1", and it is shown that the distance between the mark and the origin is "RSS1".

[0077] In the gastric cancer risk information display area e104, a graph of a two-dimensional coordinate axis showing the relationship between the gene risk value "GR2", the blood risk value "BR2", and the combined risk value "RSS2" regarding "gastric cancer" of the subject is displayed. Specifically, in the graph of the gastric cancer risk information display area e104, a mark is attached to the coordinates "GR2, BR2", and it is shown that the distance between the mark and the origin is "RSS2".

[0078] In the lung cancer risk information display area e106, a graph of a two-dimensional coordinate axis showing the relationship between the gene risk value "GR3", the blood risk value "BR3", and the combined risk value "RSS3" regarding "lung cancer" of the subject is displayed. Specifically, in the graph of the lung cancer risk information display area e106, a mark is attached to the coordinates "GR3, BR3", and it is shown that the distance between the mark and the origin is "RSS3".

[0079] According to these graphs, the subject can make a decision to prioritize the countermeasures for "gastric cancer" where both the gene risk value and the blood risk value are at a high level. Also, for "colorectal cancer" and "lung cancer", the subject can make a decision to prioritize the countermeasures for "lung cancer" which has a high genetic incidence probability.

[0080] In this example, there are the following magnitude relationships (1) to (3) among the respective risk values. (1) "GR3" > "GR2" > "GR1" (2) "BR2" > "BR1" > "BR3" (3) "RSS2" > "RSS3" > "RSS1"

[0081] If the subject has only undergone a genetic test, the subject may determine that the risks are high in the order of "lung cancer" corresponding to "GR3", "stomach cancer" corresponding to "GR2", and "colon cancer" corresponding to "GR1". That is, in this case, the subject may make a decision to prioritize the measures against "lung cancer" over other cancers.

[0082] Also, if the subject has only undergone a blood test, the subject may determine that the risks are high in the order of "stomach cancer" corresponding to "BR2", "colon cancer" corresponding to "BR1", and "lung cancer" corresponding to "BR3". That is, in this case, the subject may make a decision to prioritize the measures against "colon cancer" over the measures against "lung cancer".

[0083] On the other hand, according to the combined risk value calculated based on the results of the genetic test and the blood test, the subject may determine that the risks are high in the order of "stomach cancer" corresponding to "RSS2", "lung cancer" corresponding to "RSS3", and "colon cancer" corresponding to "RSS1". That is, in this case, as described above, the subject may make a decision to prioritize the measures against "stomach cancer" where both the genetic risk value and the blood risk value are at a high level, and then take measures against "lung cancer" which has a high genetic incidence probability as the next priority. In this way, the information processing device 2 can give the subject a suggestion different from the case where each test is performed separately by integrally analyzing a plurality of test results.

[0084] [Periodic reminder] Returning to FIG. 4, next, the information processing device 2 waits for a predetermined period (S116) and outputs again a notification prompting the implementation of a blood test (S104). The predetermined period is, for example, 3 months, 6 months, 1 year, etc. after the previous blood test. Thereafter, the information processing device 2 sequentially executes the processes of S106 - S114.

[0085] <4. Effect> Summarizing the above, the program according to one aspect of the present disclosure causes the computer 70 to function as an acquisition means 100 for acquiring the results of a genetic test and the results of a supplementary test regarding the body of the subject, where the genetic test includes a genetic test, and the supplementary test includes any one of a blood test, a urine test, and at least a part of a medical check-up related to a general medical examination; a generation means 102 for generating combined risk information indicating the cancer risk of the subject based on the results of the genetic test and the results of the supplementary test; and a risk information output means 104a for outputting the combined risk information.

[0086] As described above, according to the information processing apparatus 2, information obtained by comprehensively analyzing the results of a genetic test and the results of a supplementary test can be presented to the subject. Further, according to the information processing apparatus 2, it is possible to achieve both the comprehensiveness of the genetic test and the continuous disease prevention by the supplementary test. As a result, the presentation of the test results can be made more efficient.

[0087] In one embodiment, the generation means 102 further generates gene risk information indicating the cancer risk based on the results of the genetic test, and the risk information output means 104a further outputs the gene risk information. Also, in one embodiment, the generation means 102 further generates auxiliary risk information indicating the cancer risk based on the results of the supplementary test, and the risk information output means 104a further outputs the auxiliary risk information. Further, in one embodiment, the risk information output means 104a outputs information indicating the relationship between the combined risk information, the gene risk information, and the auxiliary risk information.

[0088] According to these configurations, the subject can simultaneously grasp the combined risk information, the gene risk information, and the auxiliary risk information. As described with reference to FIG. 9, by presenting not only the combined risk information but also the gene risk information and the auxiliary risk information to the subject, it becomes easier for the subject to formulate a policy for suppressing the cancer risk.

[0089] In one embodiment, the gene risk information includes a gene risk value calculated based on the result of a gene test, the auxiliary risk information includes an auxiliary risk value calculated based on the result of an auxiliary test, and the combined risk information includes a combined risk value calculated based on the gene risk value and the auxiliary risk value.

[0090] According to this configuration, since the risk of cancer of the subject is presented quantitatively, it becomes easier for the subject to establish a policy for suppressing the risk of cancer.

[0091] In one embodiment, the risk information output means 104a outputs a plurality of combined risk information.

[0092] According to this configuration, the subject can grasp collectively the combined risk information regarding a plurality of cancers such as, for example, "colorectal cancer", "stomach cancer", and "lung cancer". As a result, it becomes easy for the subject to determine which cancer countermeasures should be prioritized.

[0093] In one embodiment, the risk of cancer is determined based on the incidence rate of cancer of the subject and the mortality rate of the cancer. Also, in one embodiment, the incidence rate of cancer of the subject is determined based on the prevalence rate of cancer in a predetermined population and the cancer incidence magnification of the subject determined based on at least one of the result of the gene test and the result of the auxiliary test.

[0094] Generally, the risk of cancer cannot be sufficiently evaluated only by the incidence rate of cancer. For example, when the incidence rates of "prostate cancer" and "lung cancer" of the subject are the same, the risk of "lung cancer" with a higher mortality rate should be evaluated higher. According to this configuration, it becomes possible to present to the subject information that more accurately reflects the risk of cancer.

[0095] The program according to one embodiment further functions as a notification output means 104b that causes the computer 70 to output a notification prompting the subject to perform an auxiliary examination based on the acquisition means 100 having acquired the result of the genetic test. Further, in one embodiment, the notification output means 104b outputs a notification prompting the subject to conduct a consultation regarding health based on the acquisition means 100 having further acquired the result of the auxiliary examination.

[0096] According to this configuration, the usability for the subject can be improved.

[0097] The program according to one embodiment further functions as a notification output means 104b that outputs, at a predetermined time interval, a notification prompting the subject to perform an auxiliary examination regardless of whether the acquisition means 100 has acquired the result of the auxiliary examination.

[0098] Since the result of the auxiliary examination reflects the subject's lifestyle, the subject may attach importance to the transition of the result. According to this configuration, it becomes possible to track the results of the subject's auxiliary examinations at predetermined time intervals.

[0099] Note that the above-described effects are merely examples and do not limit the scope of application of the present disclosure.

[0100] <5. Hardware Configuration> With reference to FIG. 10, an example of the hardware configuration when each device included in the system 1 is realized by a computer 70 will be described. Note that the functions of each device can also be realized by dividing them among a plurality of devices.

[0101] As shown in FIG. 10, the computer 70 includes a processor 700, a storage device 702, an input I / F 704, a data I / F 706, a communication I / F 708, and a display device 710.

[0102] Processor 700 controls various processes in computer 70 by executing programs stored in storage device 702. For example, each functional unit included in control unit 10 of information processing apparatus 2 can be realized by a program stored in storage device 702 being executed by processor 700.

[0103] Storage device 702 is a storage medium such as, for example, RAM (Random Access Memory). RAM temporarily stores program codes of programs executed by processor 700 and data required during program execution.

[0104] In addition, storage device 702 is a non-volatile storage medium such as, for example, a hard disk drive (HDD) or flash memory. Storage device 702 stores an operating system and various programs for realizing the above respective configurations. The storage medium storing the various programs may be a non-transitory computer readable medium. In addition, storage device 702 can also store a table for registering various information and a DB for managing the table. Such programs and data are referred to by processor 700 by being loaded into storage device 702 as necessary.

[0105] Input I / F 704 is a device for receiving input from a user. Specific examples of input I / F 704 include a camera, buttons, a microphone, a keyboard, a mouse, a touch panel, various sensors, wearable devices, etc. Input I / F 704 may be connected to computer 70 via an interface such as, for example, USB (Universal Serial Bus).

[0106] The data I / F 706 is a device for inputting data from outside the computer 70. Specific examples of the data I / F 706 include a drive device for reading data stored in various storage media. It is also conceivable that the data I / F 706 is provided outside the computer 70. In that case, the data I / F 706 is connected to the computer 70 via an interface such as USB.

[0107] The communication I / F 708 is a device for performing data communication via the communication network 5, either wired or wirelessly, with a device outside the computer 70. It is also conceivable that the communication I / F 708 is provided outside the computer 70. In that case, the communication I / F 708 is connected to the computer 70 via an interface such as USB.

[0108] The display device 710 is a device for displaying various information. Specific examples of the display device 710 include, for example, a liquid crystal display, an organic EL (Electro-Luminescence) display, a display of a wearable device, etc. The display device 710 may be provided outside the computer 70. In that case, the display device 710 is connected to the computer 70 via, for example, a display cable. Also, when a touch panel is adopted as the input I / F 704, the display device 710 can be configured integrally with the input I / F 704.

[0109] In addition, the components included in the various devices of the system 1 described in the above embodiment are assumed to be such that the processing defined is realized in cooperation with other hardware when the program stored in the storage device 702 is executed by the processor 700. In other words, these components are assumed as software or firmware as well as the corresponding hardware, and in both concepts, they are also described as "function", "means", "section", "processing circuit", "unit", or "module", etc., and can be read as such respectively.

[0110] <6. Modification Example> The matters described in the above embodiment can be appropriately changed within a non - conflicting range.

[0111] [Inspection Order and Reminder When Inspection Has Not Been Performed Yet] In the above embodiment, an example was described in which the information processing apparatus 2 acquires the test result of the genetic test (see S100 in FIG. 4) and then acquires the test result of the auxiliary test (see S106 in FIG. 4). However, it is not limited to this. The information processing apparatus 2 may acquire the test result of the genetic test after acquiring the test result of any one of one or more auxiliary tests. Also, in the above embodiment, an example was described in which the information processing apparatus 2 acquires the test results of the genetic test and the auxiliary test (see S100 - S114 in FIG. 4), then waits for a predetermined period (see S116 in FIG. 4), and reminds the user to perform the auxiliary test again (see S104 in FIG. 4). However, it is not limited to this. The information processing apparatus 2 may remind the user to perform the test even when the user has not yet performed the genetic test and / or the auxiliary test.

[0112] These specific examples will be described with reference to FIG. 11. FIG. 11 is a flowchart showing the operation of the information processing apparatus 2 when the user performs the genetic test, blood test, and urine test in any order. In this example, it is assumed that test kits for performing the genetic test, blood test, and urine test respectively have been sent to the user in advance. By using this test kit, the user can perform the genetic test, blood test, and urine test in the order of their own choice.

[0113] First, after sending the test kit, the information processing device 2 waits for a predetermined period (S200a, S200b, S200c). Next, the information processing device 2 determines whether the tests for genetic testing, blood testing, and urine testing have already been performed, respectively (S204a, S204b, S204c). At this time, the information processing device 2 may determine whether the test has been performed by accessing the testing institution device 4, may determine whether the test has been performed based on the information input to the terminal device 3, or may determine whether the test has been performed based on the information registered by the service provider regarding the user with respect to the information processing device 2.

[0114] If any of the genetic testing, blood testing, and urine testing has not been performed (S204a NO, S204b NO, S204c NO), the information processing device 2 outputs a notification prompting the performance of the test (S210a, S210b, S210c). For example, when the user has already performed genetic testing and urine testing and has not performed blood testing, the information processing device 2 may output a notification prompting the performance of blood testing.

[0115] The information processing device 2 sequentially obtains test results from the tests determined to have been performed among genetic testing, blood testing, and urine testing (S206a, S206b, S206c), and calculates risk values (S208a, S208b, S208c). After the risk values based on each of genetic testing, blood testing, and urine testing are obtained, the information processing device 2 calculates a combined risk value based on these risk values (S212). Thereafter, the information processing device 2 outputs a notification prompting the implementation of health consultation (S214) by the same process as the process described with reference to S114 and S116 in FIG. 4, and outputs the genetic risk value, blood risk value, cancer risk value based on urine (urine risk value), and combined risk value (S216).

[0116] [Information displayed on the display screen] In the above embodiment, in the display screen example of FIG. 9, it has been described that the colorectal cancer risk information display area e102, the gastric cancer risk information display area e104, and the lung cancer risk information display area e106 are displayed. However, other information may be further displayed. In addition to these information, the terminal device 3 may further display details of the results of genetic tests, details of the results of blood tests, details of the results of urine tests (cancer risk screening tests), the calculation process of the combined risk value, changes from the previous test results, and the like.

[0117] [Combined risk information based on the results of three or more tests] In the above embodiment, mainly an example has been described in which the gene risk value included in the gene risk information, the blood risk value included in the blood risk information, and the combined risk value included in the combined risk information are presented to the user. However, it is not limited to this. Specifically, urine risk information generated based on the results of urine tests may be further presented to the user. That is, in the above embodiment, the cancer risk was presented to the user "two-dimensionally" based on the gene risk information and the blood risk information. However, by adding the urine risk information thereto, the cancer risk may be presented to the user "three-dimensionally".

[0118] Also, in the above embodiment, mainly an example has been described in which the gene risk value and the blood risk value are calculated by numerical calculation (see FIGS. 5-8). However, it is not limited to this. Specifically, when the test results include comments, the risk value may be calculated based on the comments.

[0119] Hereinafter, with reference to FIGS. 12-13, an example will be described in which, when the urine risk information includes comments, the combined risk value is calculated based on the gene risk value, the blood risk value, and an index determined based on the comments included in the urine risk information. In this example, since the index is determined based on the comments included in the urine risk information, it can also be referred to as the "urine risk value".

[0120] FIG. 12 is a diagram showing an example of a display screen for urine risk information. In the table of FIG. 12, for each of "colorectal cancer", "stomach cancer", and "lung cancer", an evaluation determined based on the results of a urine test, a comment on the urine test, and an index corresponding to the comment are displayed in association with each other.

[0121] The evaluation of the urine test may be determined according to a predetermined calculation based on the results of the urine test, or may be determined by a doctor who has seen the results of the urine test based on his or her own judgment. In FIG. 12, regarding the evaluation of the urine test, "Rank C", "Rank C", and "Rank A" are associated with "colorectal cancer", "stomach cancer", and "lung cancer", respectively. That is, it is shown that the evaluations for "colorectal cancer" and "stomach cancer" are poor, and the evaluation for "lung cancer" is good.

[0122] The comment on the urine test is typically input by a doctor who has seen the results of the urine test. In FIG. 12, regarding the comment on the urine test, for "colorectal cancer", the comment "Some points of concern were found in the test. Although further detailed tests are necessary, please don't worry too much. Early detection is the key in many cases." is associated. Also, for "stomach cancer", the comment "Looking at today's test results, unfortunately some abnormalities were found. This means that more specialized investigations and treatments may be required. First, let's calm down and consider the next steps." is associated. Also, for "lung cancer", the comment "The results of this test were negative, and no signs of cancer were found. However, in order to maintain your health in the future, please pay attention to a balanced diet, regular exercise, and sufficient sleep." is associated. Thus, according to the evaluation of the urine test, both "colorectal cancer" and "stomach cancer" are "Rank C", but when considering the comments on the urine test, it can be understood that the actual degree of badness is different.

[0123] Regarding the indicators, for each of "colorectal cancer", "stomach cancer", and "lung cancer", values of "CR1", "CR2", and "CR3" are associated. In this example, assume they are "6", "11", and "3" respectively. The indicator is determined based on the comment on the urine test and the keyword information in which the importance of each of one or more keywords included in the comment is associated with the keyword.

[0124] Figure 13 is a diagram showing an example of keyword information. In the table of Figure 13, for each of one or more keywords such as "diet", "sleep", "exercise", "concerned", "detail", "early detection", "treatment", "abnormality", "specialty", and "investigation", importance levels of "1", "1", "1", "2", "2", "2", "2", "3", "3", and "3" are associated.

[0125] Returning to Figure 12, the comment for "colorectal cancer" includes keywords "concerned", "detail", and "early detection". Since the total importance associated with these keywords is "6", the "CR1" of the indicator for "colorectal cancer" is displayed as "6".

[0126] The comment for "stomach cancer" includes keywords "abnormality", "specialty", "investigation", and "treatment". Since the total importance associated with these keywords is "11", the "CR2" of the indicator for "stomach cancer" is displayed as "11".

[0127] The comment for "lung cancer" includes keywords "diet", "exercise", and "sleep". Since the total importance associated with these keywords is "3", the "CR3" of the indicator for "lung cancer" is displayed as "3".

[0128] In the above-described embodiment, the information processing apparatus 2 has been described as calculating the combined risk value by taking the square root of the sum of the squares of the gene risk value and the blood risk value. However, the information processing apparatus 2 may calculate the combined risk value based on the index determined as described above. For example, the information processing apparatus 2 may perform processing such as normalization on each of the gene risk value, the blood risk value, and the index (i.e., the urine risk value), and then calculate the combined risk value by taking the square root of the sum of their squares.

[0129] FIG. 14 is a diagram showing an example of a display screen when combined risk information is calculated by taking into account urine risk information in addition to the display screen example of FIG. 9. Specifically, FIG. 14 is a diagram showing an example of a display screen in which the relationship between the gene risk value, the blood risk value, and the urine risk value and the combined risk value calculated by taking the square root of the sum of the squares of these values is displayed. More specifically, in the colorectal cancer risk information display area e102, the relationship between the gene risk value "GR1", the blood risk value "BR1", the urine risk value "CR1", and the combined risk value "RSS1" regarding colorectal cancer is shown on a three-dimensional graph. Similarly, in the gastric cancer risk information display area e104, the relationship between the gene risk value "GR2", the blood risk value "BR2", the urine risk value "CR2", and the combined risk value "RSS2" regarding gastric cancer is shown on a three-dimensional graph. Similarly, in the lung cancer risk information display area e106, the relationship between the gene risk value "GR3", the blood risk value "BR3", the urine risk value "CR3", and the combined risk value "RSS3" regarding lung cancer is shown on a three-dimensional graph.

[0130] According to this configuration, it becomes possible to more comprehensively determine the cancer risk compared to the case of using two test results. Specifically, by quantifying and visualizing a plurality of test results and the combined risk value determined based on the plurality of test results as, for example, a scalar value, the user can more easily analyze the test results and utilize them for improving their lifestyle and the like. In addition, by determining the index based on the comment, a more detailed evaluation can be performed compared to the case of evaluating the cancer risk in, for example, three levels from A to C.

[0131] So far, an example of determining an index corresponding to the urine risk value based on the comments included in the urine test results has been described. However, when the gene test results include comments, an index corresponding to the gene risk value may be determined based on the comments. When the blood test results include comments, an index corresponding to the blood risk value may be determined based on the comments.

[0132] [Other Modification Examples] In the above embodiment, an example in which the subject undergoes a gene test and an auxiliary test has been described, but the present invention is not limited thereto. Specifically, the subject may perform at least two of a gene test, a blood test, a urine test, and a comprehensive medical examination, and the information processing device 2 may generate combined risk information based on the results of the two tests.

[0133] In the above embodiment, an example in which the subject undergoes a gene test and one auxiliary test has been described, but the present invention is not limited thereto. Specifically, in addition to the gene test, the subject may perform a plurality of auxiliary tests, and the information processing device 2 may generate combined risk information based on the results of the gene test and the results of each of the plurality of auxiliary tests. In this case, the graph described with reference to FIG. 9 may be represented by a graph having three or more coordinate axes, and the results of some of the plurality of auxiliary tests may be displayed according to the subject's selection.

[0134] The gene risk value and the auxiliary risk value may be output from the information processing device 2 to the subject terminal device 3a after being subjected to appropriate processing (for example, normalization, etc.) other than the processing described in the above embodiment.

[0135] <7. Embodiments of the Present Disclosure> The present disclosure includes, for example, the following embodiments. The correspondence with the above embodiments is shown in parentheses.

[0136] [Appendix 1] A program according to an aspect of the present disclosure causes a computer 70 to function as an acquisition unit 100 that acquires results of a first examination (genetic examination) and a second examination (auxiliary examination) regarding a subject's body, where the first examination (genetic examination) includes a genetic examination, and the second examination (auxiliary examination) includes any one of a blood test, a urine test, and at least a part of an examination related to a comprehensive medical checkup; a generation unit 102 that generates combined risk information indicating the risk of a predetermined disease (cancer) of the subject based on the results of the first examination (genetic examination) and the second examination (auxiliary examination); and a risk information output unit 104a that outputs the combined risk information.

[0137] [Appendix 2] In the program according to Appendix 1, the generation unit 102 may further generate first risk information (gene risk information) indicating the risk of a predetermined disease (cancer) based on the results of the first examination (genetic examination), and the risk information output unit 104a may further output the first risk information (gene risk information).

[0138] [Appendix 3] In the program according to Appendix 2, the generation unit 102 may further generate second risk information (auxiliary risk information) indicating the risk of a predetermined disease (cancer) based on the results of the second examination (auxiliary examination), and the risk information output unit 104a may further output the second risk information (auxiliary risk information).

[0139] [Appendix 4] In the program according to Appendix 3, the acquisition unit 100 is a third examination that is any one of a blood test, a urine test, and at least a part of an examination related to a comprehensive medical checkup, and further includes the results of a third examination that is different from the second examination. The generation unit 102 further generates third risk information indicating the risk of a predetermined disease based on the results of the third examination, and may include a comment determined based on the results of the third examination and an index corresponding to the comment. The index corresponding to the comment may be determined based on the comment and information (keyword information) in which the importance of each of one or more keywords included in the comment is associated.

[0140] [Appendix 5] In the program described in Appendix 4, the generation means 102 may generate combined risk information based further on an index.

[0141] [Appendix 6] In the program described in any one of Appendices 3 to 5, the risk information output means 104a may output information indicating the relationship between the combined risk information, the first risk information (gene risk information), and the second risk information (auxiliary risk information).

[0142] [Appendix 7] In the program described in any one of Appendices 3 to 6, the first risk information (gene risk information) may include a first risk value (gene risk value) calculated based on the result of the first test (gene test), the second risk information (auxiliary risk information) may include a second risk value (auxiliary risk value) calculated based on the result of the second test (auxiliary test), and the combined risk information may include a combined risk value calculated based on the first risk value (gene risk value) and the second risk value (auxiliary risk value).

[0143] [Appendix 8] In the program described in any one of Appendices 1 to 7, the risk information output means 104a may output a plurality of combined risk information.

[0144] [Appendix 9] In the program described in any one of Appendices 1 to 8, the risk of a predetermined disease (cancer) may be determined based on the onset risk (incidence rate) of the predetermined disease (cancer) of the subject and the risk of exacerbation (mortality rate) of the predetermined disease (cancer).

[0145] [Appendix 10] In the program described in Supplementary Note 9, the onset risk (incidence rate) of a predetermined disease (cancer) in a subject may be determined based on the prevalence of the predetermined disease (cancer) in a predetermined population and the susceptibility (multiplication factor of onset) of the subject to develop the predetermined disease (cancer) determined based on at least one of the results of the first examination (genetic examination) and the results of the second examination (auxiliary examination).

[0146] [Supplementary Note 11] The program described in any one of Supplementary Notes 1 to 10 may further cause the computer 70 to function as notification output means 104b that outputs a notification prompting the subject to perform a second examination (auxiliary examination) based on the acquisition means 100 having acquired the results of the first examination (genetic examination).

[0147] [Supplementary Note 12] In the program described in Supplementary Note 11, the notification output means 104b may output a notification prompting the subject to conduct health consultations based on the acquisition means 100 having further acquired the results of the second examination (auxiliary examination).

[0148] [Supplementary Note 13] The program described in any one of Supplementary Notes 1 to 12 may further cause the computer 70 to function as notification output means 104b that outputs, at predetermined time intervals, a notification prompting the subject to perform a second examination (auxiliary examination) regardless of whether the acquisition means 100 has acquired the results of the second examination (auxiliary examination).

[0149] [Supplementary Note 14] In the program described in any one of Supplementary Notes 1 to 13, the predetermined disease may be cancer.

[0150] [Supplementary Note 15] A program according to another aspect of the present disclosure causes a computer 70 to function as an acquisition unit 100 that acquires the results of a first examination regarding a subject's body and the results of a second examination different from the first examination, where the first examination and the second examination each include at least one of a genetic test, a blood test, a urine test, and an examination related to a general medical check-up; a generation unit 102 that generates first risk information indicating the risk of a predetermined disease (cancer) estimated based on the results of the first examination and generates combined risk information indicating the risk of a predetermined disease (cancer) based on the results of the first examination and the results of the second examination; and a risk information output unit 104a that outputs the first risk information and the combined risk information.

[0151] [Appendix 16] An information processing apparatus 2 according to another aspect of the present disclosure includes an acquisition unit that acquires the results of a first examination (genetic test) and a second examination (auxiliary test) regarding a subject's body, where the first examination (genetic test) includes a genetic test and the second examination (auxiliary test) includes at least one of a blood test, a urine test, and a general medical check-up; a generation unit that generates combined risk information indicating the risk of a predetermined disease (cancer) of the subject based on the results of the first examination (genetic test) and the results of the second examination (auxiliary test); and a risk information output unit that outputs the combined risk information. It is provided with.

[0152] [Appendix 17] An information processing method according to another aspect of the present disclosure includes causing a computer 70 to execute a step of acquiring the results of a first examination (genetic test) and a second examination (auxiliary test) regarding a subject's body, where the first examination (genetic test) includes a genetic test and the second examination (auxiliary test) includes at least one of a blood test, a urine test, and a general medical check-up; a step of generating combined risk information indicating the risk of a predetermined disease (cancer) of the subject based on the results of the first examination (genetic test) and the results of the second examination (auxiliary test); and a step of outputting the combined risk information.

Explanation of Reference Numerals

[0153] 1... System, 2... Information processing device, 3... Terminal device, 3a... Subject terminal device, 3b... Counselor terminal device, 4... Inspection institution device, 4a... Genetic inspection institution device, 4b... Auxiliary inspection institution device, 5... Communication network, 10... Control unit, 12... Storage unit, 70... Computer, 100... Acquisition means, 102... Generation means, 104... Output means, 104a... Risk information output means, 104b... Notification output means, 106... Analysis means

Claims

1. A program that causes a computer to function as: an acquisition means for acquiring the results of a first examination and a second examination regarding the body of a subject, wherein the first examination includes a genetic test, and the second examination includes any one of a blood test, a urine test, and at least a part of an examination related to a comprehensive medical checkup; a generation means for generating combined risk information indicating the risk of a predetermined disease of the subject based on the results of the first examination and the second examination; a risk information output means for outputting the combined risk information.

2. The generation means further generates first risk information indicating the risk of the predetermined disease based on the results of the first examination, and the risk information output means further outputs the first risk information. The program according to claim 1.

3. The generation means further generates second risk information indicating the risk of the predetermined disease based on the results of the second examination, and the risk information output means further outputs the second risk information. The program according to claim 2.

4. The acquisition means is a third examination that is any one of a blood test, a urine test, and at least a part of an examination related to a comprehensive medical checkup, and further includes the results of a third examination different from the second examination, the generation means further generates third risk information indicating the risk of the predetermined disease based on the results of the third examination, the third risk information includes a comment determined based on the results of the third examination and an index corresponding to the comment, and the index corresponding to the comment is determined based on the comment and information in which the importance of each of one or more keywords included in the comment is associated. The program according to claim 3.

5. The generation means further generates the combined risk information based on the index. The program according to claim 4.

6. The risk information output means outputs information indicating the relationship between the combined risk information, the first risk information, and the second risk information. The program according to claim 3.

7. The first risk information includes a first risk value calculated based on the results of the first examination, and the second risk information includes a second risk value calculated based on the results of the second examination. The program according to claim 3, wherein the combined risk information includes a combined risk value calculated based on the first risk value and the second risk value.

8. The program according to claim 1, wherein the risk information output means outputs a plurality of pieces of the combined risk information.

9. The program according to claim 1, wherein the risk of the predetermined disease is determined based on the onset risk of the predetermined disease of the subject and the risk of exacerbation of the predetermined disease.

10. The program according to claim 9, wherein the onset risk of the predetermined disease of the subject is determined based on the prevalence of the predetermined disease in a predetermined population and the susceptibility of the subject to onset of the predetermined disease determined based on at least one of the result of the first examination and the result of the second examination.

11. The computer is further caused to function as notification output means that outputs a notification prompting the subject to perform the second examination based on the acquisition means having acquired the result of the first examination, the program according to claim 1.

12. The program according to claim 11, wherein the notification output means outputs a notification prompting the subject to conduct a consultation on health based on the acquisition means having further acquired the result of the second examination.

13. The computer is further caused to function as notification output means that outputs, at predetermined time intervals, a notification prompting the subject to perform the second examination regardless of whether the acquisition means has acquired the result of the second examination, the program according to claim 1.

14. The program according to any one of claims 1 to 13, wherein the predetermined disease is cancer.

15. A computer is provided with acquisition means for acquiring the result of a first examination regarding the body of a subject and the result of a second examination different from the first examination, wherein the first examination and the second examination each include any one of a genetic test, a blood test, a urine test, and at least a part of an examination related to a comprehensive medical checkup; generation means for generating first risk information indicating the risk of a predetermined disease estimated based on the result of the first examination and generating combined risk information indicating the risk of the predetermined disease based on the result of the first examination and the result of the second examination; risk information output means for outputting the first risk information and the combined risk information; A program that functions as

16. An acquisition unit that acquires the results of a first examination and a second examination regarding the body of a subject, wherein the first examination includes a genetic test, and the second examination includes any one of a blood test, a urine test, and a comprehensive medical checkup, and the acquisition unit A generation unit that generates combined risk information indicating the risk of a predetermined disease of the subject based on the results of the first examination and the results of the second examination A risk information output unit that outputs the combined risk information An information processing apparatus comprising

17. Causing a computer to Acquire the results of a first examination and a second examination regarding the body of a subject, wherein the first examination includes a genetic test, and the second examination includes any one of a blood test, a urine test, and a comprehensive medical checkup, and the step of acquiring Generate combined risk information indicating the risk of a predetermined disease of the subject based on the results of the first examination and the results of the second examination Output the combined risk information An information processing method for executing

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