Incubation device, incubation system, and sample analyzer

Abstract

SOLUTION: An incubation device, an incubation system, and a sample analyzer are provided. The incubation device includes: a bearing portion 10 having an open bearing region and a closed bearing region, a first bearing hole 11 being provided in the open bearing region, and a second bearing hole being provided in the closed bearing region; and a cover plate structure 20 provided in the closed bearing region and having an opening position and a closing position, the cover plate structure covering an upper side of the closed bearing region when the cover plate structure is at the closing position, and the cover plate structure avoiding the closed bearing region to expose the second bearing hole when the cover plate structure is at the opening position.EFFECT: A problem in the related art, where items prone to volatilization or evaporation during an incubation process are separately incubated outside a reaction system, resulting in a tedious operation, can be effectively solved.SELECTED DRAWING: Figure 1

Description

[Technical Field]

[0001] The present invention relates to the field of medical devices, in particular to incubation devices, incubation systems and sample analyzers. [Background technology]

[0002] In this field, a sample analyzer is used to detect samples such as blood, and typically includes a consumable box supply system, an injection system, a reaction system, a measurement system, etc., of which the reaction system is an essential component of the sample analyzer, and is used to perform incubation operations and provide appropriate reaction temperatures for the reactants in the reaction cup.

[0003] In related art, for items that are prone to volatilization or evaporation during the incubation process, in order to avoid affecting other normal items, the incubation operation is generally performed independently outside the reaction system, for example, in a water bath. After the incubation is completed, the operator places the reactant in a sample analyzer for detection. This makes the operation relatively cumbersome, requires a relatively large amount of operator work, and requires a lot of manual intervention, making it prone to errors. Summary of the Invention [Problem to be solved by the invention]

[0004] The main object of the present invention is to provide an incubation device, an incubation system, and a sample analysis device that solve the problem in related art that items that are prone to volatilization or evaporation during the incubation process are incubated independently outside the reaction system, making the operation complicated. [Means for solving the problem]

[0005] In order to achieve the above object, according to one aspect of the present invention, there is provided an incubation device including: a mounting section having an open mounting area and a sealed mounting area, with a first mounting hole provided in the open mounting area and a second mounting hole provided in the sealed mounting area; and a cover plate structure provided in the sealed mounting area, having an open position and a closed position, covering the top of the sealed mounting area when in the closed position, and retracting from the sealed mounting area to expose the second mounting hole when in the open position.

[0006] Furthermore, a gripping groove may be provided in the sealed mounting area, and the second mounting hole may be provided in a groove bottom wall of the gripping groove.

[0007] Furthermore, the structure of the second mounting hole may be similar to the structure of the first mounting hole, and / or the open mounting area may have a plurality of first mounting holes arranged in a matrix, and / or the sealed mounting area may have a plurality of second mounting holes arranged in a matrix, and a plurality of partition plates may be provided in the gripping groove, and the plurality of partition plates may divide the gripping groove to form a plurality of gripping cavities that are independent of each other, and the plurality of gripping cavities may be arranged to correspond one-to-one to the plurality of second mounting holes, and the cross-sectional area of the gripping cavity may be larger than the cross-sectional area of the corresponding second mounting hole, and the upper surface of the partition plate may be flush with the upper surface of the sealed mounting area.

[0008] Furthermore, when the reaction cup is placed in the first mounting hole and the cover plate structure is in the closed position, the upper surface of the cover plate structure may be flush with or lower than the upper surface of the reaction cup.

[0009] Furthermore, the cover plate structure may include a pivot shaft drilled in the mounting portion and a rotatable plate fixedly connected to the pivot shaft, and the pivot shaft may be configured to rotate the rotatable plate so that the cover plate structure can be switched between a closed position and an open position.

[0010] Additionally, the incubation device may further include a position sensing structure for detecting the position of the cover plate structure.

[0011] Furthermore, the position sensing structure may include a sensing groove and a sensing member provided on the pivot shaft, and when the pivot shaft is rotated, the sensing member may be switched between a state in which it is inserted into the sensing groove and a state in which it is positioned outside the sensing groove.

[0012] Furthermore, the incubation device may further include a drive unit, which includes a drive motor provided below the mounting unit and a power transmission structure provided between the drive motor and the rotating shaft, and the power transmission structure may include a first power transmission gear fitted onto the output shaft of the drive motor, a second power transmission gear fitted onto the rotating shaft, and a power transmission belt wound around the outside of the first power transmission gear and the second power transmission gear.

[0013] Furthermore, the mounting portion may include a constant temperature member, a heating member, and a heat-insulating layer, the first mounting hole and the second mounting hole may both be provided in the constant temperature member, the heating member may be provided adjacent to the constant temperature member, and may heat the constant temperature member to 20°C to 50°C, and the heat-insulating layer may cover the outer periphery and bottom of the constant temperature member and the heating member.

[0014] According to another aspect of the present invention, there is provided an incubation system comprising an incubation device and a reaction cup, wherein the incubation device is the above-described incubation device, and the reaction cup has an upper opening and can be placed in the first mounting hole or the second mounting hole.

[0015] According to another aspect of the present invention, there is provided a sample analysis device including the above-described incubation device or the above-described incubation system. [Effects of the Invention]

[0016] According to the technical solution of the present invention, the mounting part is for mounting the reaction cup and providing a suitable incubation temperature for the sample in the reaction cup. The mounting section includes an open mounting area, which has a first mounting hole, and a reaction cup can be left in the first mounting hole to perform a normal item in which evaporation or vaporization is unlikely to occur. The mounting section further includes a sealed mounting area, which has a second mounting hole, and a cover plate structure which is located in the sealed mounting area and has an open position and a closed position. When the cover plate structure is in the open position, it is retracted from the sealed mounting area to expose the second mounting hole. In this case, the reaction cup can be left in the second mounting hole. After the reaction cup has been left in place, the cover plate structure can be switched from the open position to the closed position, covering the top of the sealed mounting area, thereby reducing the amount of evaporation or vaporization of the sample in the reaction cup and reducing changes in the concentration of the sample. In other words, the reaction cup can be placed in the second mounting hole to perform a special item in which evaporation or vaporization is likely to occur. In this application, incubation of normal items and special items is integrated into one incubation device, and the operation of placing the reaction cup 1 in the first or second mounting hole and the operation of switching the cover plate structure between the open and closed positions can both be achieved by machines, eliminating the need for manual operation by the operator, thereby reducing the labor intensity of the operator and avoiding operational errors that may result from the introduction of manual operation. Therefore, the technical solution of this application effectively solves the problem in related art that items that are prone to volatilization or evaporation during the incubation process are incubated separately outside the reaction system, making the operation complicated. [Brief explanation of the drawings]

[0017] The drawings constituting a part of this application are intended to provide a further understanding of the present invention, and the illustrative embodiments and descriptions thereof are intended to provide an understanding of the present invention and are not intended to unduly limit the present invention. [Figure 1]1 is a diagram showing the three-dimensional structure of an embodiment of the incubation device according to the present invention, in which the cover plate structure is in the closed position; [Figure 2] 2 shows an enlarged view of a portion A of the incubation device of FIG. 1. [Figure 3] 2 shows a schematic plan view of the incubation device of FIG. 1. [Figure 4] 2 shows a cross-sectional schematic view of the incubation device of FIG. 1. [Figure 5] 5 shows an enlarged view of a portion B of the incubation device of FIG. 4. [Figure 6] 2 shows a schematic cross-sectional view of another portion of the incubation device of FIG. 1. [Figure 7] 2 is a view showing the three-dimensional structure of the incubation device of FIG. 1 from another angle, in which the cover plate structure is in the open position; FIG. [Figure 8] 8 shows an enlarged view of a portion C of the incubation device in FIG. 7. [Figure 9] 1 shows a schematic cross-sectional view of an embodiment of an incubation system according to the present invention, in which the cover plate structure is in a closed position. [Figure 10] 10 shows an enlarged view of a portion D of the incubation system of FIG. 9. DETAILED DESCRIPTION OF THE INVENTION

[0018] The technical solutions of the embodiments of the present invention will be described clearly and completely below with reference to the drawings. However, it should be understood that the embodiments described below are only some of the embodiments of the present invention, and not all of the embodiments of the present invention. The description of at least one exemplary embodiment below is for illustrative purposes only and does not limit the present invention and its applications or uses. Other embodiments that a person skilled in the art can obtain based on the embodiments of the present invention without exerting inventive efforts are also included in the scope of protection of the present invention.

[0019] It should be noted that the terms used herein are for the purpose of describing modes for implementing the present invention and are not intended to limit the exemplary embodiments of the present application. Furthermore, as used herein, the singular also includes the plural unless otherwise specified herein. Furthermore, when the terms "comprise" and / or "include" are used herein, they should be understood to specify features, steps, operations, devices, components, and / or combinations thereof.

[0020] Furthermore, unless specifically stated otherwise, the relative arrangements of components and steps, formulas, and numerical values described in these embodiments do not limit the scope of the present invention. It goes without saying that, for convenience of explanation, the dimensions of each part shown in the drawings are not drawn to scale. Although techniques, methods, and equipment known to those skilled in the art are not described in detail, such techniques, methods, and equipment should be considered part of the specification, where appropriate. In all examples illustrated and described herein, any specific values should be construed as merely illustrative and not limiting. Therefore, other examples of the exemplary embodiments may have different values. Note that similar symbols and letters indicate similar objects in the following drawings, and once one is defined in one drawing, further description in subsequent drawings is unnecessary.

[0021] As shown in Figures 1, 3 and 7, the present application provides an incubation apparatus, and an embodiment of the incubation apparatus of the present application includes a mounting portion 10 and a cover plate structure 20, wherein the mounting portion 10 has an open mounting area 101 and a sealed mounting area 102, a first mounting hole 11 is provided in the open mounting area 101, and a second mounting hole 12 is provided in the sealed mounting area 102, and the cover plate structure 20 is provided in the sealed mounting area 102 and has an open position and a closed position, and when positioned in the closed position, it covers the top of the sealed mounting area 102, and when positioned in the open position, it is retracted from the sealed mounting area 102 to expose the second mounting hole 12.

[0022] Applying the technical solution of this embodiment, the mounting part 10 is for mounting the reaction cup 1 to provide an appropriate incubation temperature for the sample in the reaction cup 1. The mounting part 10 includes an open mounting area 101, which is provided with a first mounting hole 11, and the reaction cup 1 can be left in the first mounting hole 11 to perform normal tasks that are less likely to cause volatilization or evaporation. The mounting section 10 further includes a sealed mounting area 102, within which a second mounting hole 12 is provided, and the cover plate structure 20 is provided in the sealed mounting area 102 and has an open position and a closed position. When the cover plate structure 20 is in the open position, it is retracted from the sealed mounting area 102 to expose the second mounting hole 12. In this case, the reaction cup 1 can be left in the second mounting hole 12. After the reaction cup 1 has been placed, the cover plate structure 20 can be switched from the open position to the closed position, covering the top of the sealed mounting area 102, thereby reducing the amount of evaporation or volatilization of the sample in the reaction cup 1 and reducing changes in the concentration of the sample. In other words, the reaction cup 1 can be left in the second mounting hole 12 to perform special tasks in which volatilization or volatilization is likely to occur. In this embodiment, incubation for normal items and special items is integrated into one incubation device, and the operation of placing the reaction cup 1 in the first or second mounting hole 11 or 12 and the operation of switching the cover plate structure 20 between the open and closed positions can both be achieved by machines, eliminating the need for manual operation by the operator, thereby reducing the labor intensity of the operator and avoiding operational errors that may result from manual operation. Therefore, the technical solution of this embodiment effectively solves the problem in related art that items that are prone to volatilization or evaporation during the incubation process are incubated separately outside the reaction system, making the operation complicated.

[0023] When explaining this embodiment, items that are unlikely to volatilize or evaporate during the incubation process may be referred to as "normal items," and items that are likely to volatilize or evaporate during the incubation process may be referred to as "special items."

[0024] For example, blood coagulation detection typically requires incubation at 37°C for 1–5 minutes. A test like the APTT calibration test requires a longer incubation period; the operator typically completes the incubation for 2 hours in a water bath outside the incubation device. Because sample evaporation during this process is likely, this test is considered a special test. APTT stands for activated partial thromboplastin time (APTT). It is a blood coagulation function test indicator that reflects the overall activity of the intrinsic blood coagulation pathway, particularly the first-phase blood coagulation factors. It is widely used to screen for deficiencies in intrinsic blood coagulation factors, such as factors XI, VIII, and IX, and is also used in the early screening and diagnosis of bleeding disorders and in laboratory monitoring of heparin anticoagulation therapy. Calibration tests, also known as mixing studies, involve proportionally mixing a patient's plasma with a normal plasma sample, followed by retesting the relevant test items. When performing an APTT calibration test in the incubation device of this embodiment, not only can the amount of evaporation during the incubation process be reduced, but the incubation operations are performed in different loading holes, so that when the item is incubated in the second loading hole 12, the normal item can still be incubated in the first loading hole 11, and the experimental process of the normal item will not be affected.

[0025] Naturally, the incubation device of this embodiment is applicable not only to items that cause evaporation due to long-term incubation, such as APTT calibration tests, but also to other items in which the sample itself or the reagent itself has strong volatility.

[0026] Furthermore, for detection of blood coagulation and other conditions, doctors or experimenters typically need to compare and analyze the results of normal and special tests to obtain comprehensive analysis results. However, in conventional techniques, normal tests are performed in an automated incubation device, while special tests are performed independently in a water bath using a reaction cup with a lid. Because the incubation environments and transfer paths for normal and special tests are different, significant detection errors are introduced, requiring the doctor or experimenter to have a high level of experience. In this embodiment, the incubations for normal and special tests are integrated into a single incubation device, which maintains consistency in other environmental characteristics, reaction cup transfer paths, etc., and is advantageous for controlling variables, thereby enabling doctors or experimenters to obtain reliable analysis results when comprehensively analyzing normal and special tests.

[0027] When the cover plate structure 20 is in the closed position, it may be in close contact with the top surface of the sealed placement area 102, or may be in pressure contact with the top surface without being sealed.

[0028] 7 and 8, the sealed placement area 102 is provided with a gripping groove 16, and the second placement hole 12 is provided in the groove bottom wall of the gripping groove 16. By providing the gripping groove 16 and the second placement hole 12 in the groove bottom wall of the gripping groove 16, the upper surface of the reaction cup 1 placed in the second placement hole 12 can be made lower or flush with the upper surface of the sealed placement area 102. Furthermore, when the cover plate structure 20 is placed on the upper surface of the sealed placement area 102, the inside of the sealed placement area 102 can be relatively sealed, thereby preventing or reducing the occurrence of evaporation or volatilization. At the same time, a gripping mechanism for clamping the reaction cup 1 can be inserted into the gripping groove 16 to place or remove the reaction cup 1.

[0029] 1, 3, 4, 5, and 7, the mounting section 10 includes a constant temperature member 13, a heating member 14, and a heat-retaining layer 15. The first mounting hole 11 and the second mounting hole 12 are both provided in the constant temperature member 13, the heating member 14 is provided adjacent to the constant temperature member 13, and can heat the constant temperature member 13 to 20°C to 50°C, and the heat-retaining layer 15 covers the outer periphery and bottom of the constant temperature member 13 and the heating member 14. The thermostatic member 13 is made of aluminum alloy 6063-T5 and includes a first thermostatic block and a second thermostatic block that are integrally arranged, of which the space occupied by the first thermostatic block forms an open mounting area 101, and the space occupied by the second thermostatic block forms a sealed mounting area 102. The heating member 14 is a PI heating film or a silicone rubber heating belt that is attached to the bottom of the thermostatic member 13. The heat-insulating layer 15 is made of heat-insulating cotton and is coated around the thermostatic member 13 and the heating member 14 and on the bottom of the heating member 14. By leaving only the top surface of the thermostatic member 13 exposed, heat exchange between the mounting area 10 and the outside is reduced and the temperature of the thermostatic member 13 is maintained stable.

[0030] The incubation device in this embodiment is not limited to application to blood coagulation detection, which involves incubation at 37°C, but may also be similarly applied to other items that involve incubation at relatively low temperatures (20°C to 50°C).

[0031] In this embodiment, the open placement area 101 and the sealed placement area 102 share one constant temperature element 13 and one heating element 14, which can save costs and is advantageous for controlling variables, helping doctors to reach reliable analytical conclusions.

[0032] As shown in Figures 3, 4, 6 and 7, the incubation device further includes a temperature sensor 181, a temperature control switch 182 and a support member 19, the support member 19 is connected to the outer periphery of the mounting portion 10 and is also connected to the housing of the sample analysis device so as to fix the incubation device to the housing, the temperature sensor 181 is provided in the central region of the constant temperature member 13 and can detect the temperature of the constant temperature member 13, and the temperature control switch 182 is electrically connected to the temperature sensor 181 and the heating member 14 and controls the heating member 14 to stop heating when the temperature sensor 181 detects that the temperature of the constant temperature member 13 has exceeded a predetermined value.

[0033] As shown in Figures 4, 7 and 8, the structure of the second mounting hole 12 is similar to the structure of the first mounting hole 11. In this way, the first mounting hole 11 and the second mounting hole 12 can be combined with the same type of reaction cup 1, which reduces the types of reaction cup 1 that can be combined with the incubation device, while allowing incubation using the same type of reaction cup 1 for special items and normal items, further reducing the introduction of errors during comprehensive comparison and analysis, resulting in more accurate analysis results.

[0034] As shown in FIGS. 3, 7, and 8, the open mounting area 101 has a plurality of first mounting holes 11 arranged in a matrix, and the sealed mounting area 102 has a plurality of second mounting holes 12 arranged in a matrix. Since both the plurality of first mounting holes 11 and the plurality of second mounting holes 12 are arranged in a matrix, the path of the gripping mechanism can be easily controlled. Specifically, the open mounting area 101 has 36 first mounting holes 11 arranged in a 2×18 pattern, and the sealed mounting area 102 has 6 second mounting holes 12 arranged in a 1×6 pattern. Naturally, in a specific implementation, the number and matrix arrangement of the first mounting holes and the number and matrix arrangement of the second mounting holes are not limited to the above format and can be set by a designer as needed.

[0035] As shown in Figures 4, 8 and 9, the sealed loading area 102 has a plurality of second loading holes 12 arranged in a matrix, and a plurality of partition plates 17 are provided within the gripping groove 16. The partition plates 17 divide the gripping groove 16 to form a plurality of gripping cavities 161 that are independent of each other, and the plurality of gripping cavities 161 are arranged to correspond one-to-one to the plurality of second loading holes 12, and the cross-sectional area of the gripping cavity 161 is larger than the cross-sectional area of the corresponding second loading hole 12, and the upper surface of the partition plate 17 is flush with the upper surface of the sealed loading area 102. By providing the partition plate 17, when the cover plate structure 20 is in the closed position, multiple independent incubation spaces are formed in the sealed mounting area 102, and each incubation space can be used to incubate a sample in one reaction cup 1. This arrangement reduces cross-contamination between samples in adjacent second mounting holes 12 during the incubation process, which could affect the accuracy of the detection results. By making the cross-sectional area of the gripping cavity 161 larger than that of the corresponding second mounting hole 12, a gripping space is formed between the upper end of the reaction cup 1 and the cavity wall of the gripping cavity 161, making it easier for a gripping mechanism to insert into the gripping space to deposit or remove the reaction cup 1.

[0036] As shown in Figures 4 and 9, the second constant temperature block protrudes higher than the first constant temperature block, and an enclosing structure is formed between the circumferential side wall of the second constant temperature block and the circumferential side wall of the gripping groove 16. When the cover plate structure 20 is positioned in the closed position, the lower surface of the inverting plate 22 abuts against the upper surface of the enclosing structure and the upper surface of the partition plate 17, thereby forming multiple incubation spaces that are independent of each other in the sealed loading area 102.

[0037] 9, when the reaction cup 1 is placed in the first mounting hole 11 and the cover plate structure 20 is in the closed position, the upper surface of the cover plate structure 20 is flush with or lower than the upper surface of the reaction cup 1. In this way, when the incubation device is simultaneously incubating normal and special items, the gripping mechanism can operate normally above the incubation device without performing complex movements such as retraction.

[0038] 1 and 7, the cover plate structure 20 includes a rotating shaft 21 drilled in the mounting portion 10 and a translating plate 22 fixedly connected to the rotating shaft 21. The rotating shaft 21 rotates the translating plate 22, thereby switching the cover plate structure 20 between a closed position and an open position. Providing the translating plate 22 as a structure covering the upper part of the sealed mounting area 102 and driving the translating plate 22 to swing by the rotating shaft 21 has the advantages of a simple structure and reliable control.

[0039] 1 to 3, the incubation device further includes a position sensing structure 30 for detecting the position of the cover plate structure 20. The position sensing structure 30 detects the position of the cover plate structure 20, thereby determining whether the cover plate structure 20 is in the closed position or the open position.

[0040] Specifically, as shown in FIGS. 1 and 2 , the position sensing structure 30 includes a sensing groove 31 and a sensing element 32 mounted on the pivot shaft 21. When the pivot shaft 21 is rotated, the sensing element 32 can be switched between being inserted into the sensing groove 31 and being positioned outside the sensing groove 31. In this embodiment, the position sensing structure 30 further includes two sensing arms 33 spaced apart from each other and a connecting arm 34 connected to the ends of the two sensing arms 33. The two sensing arms 33 and the connecting arm 34 jointly form the sensing groove 31, one of which can transmit an optically coupled signal, and the other can receive the optically coupled signal. When the cover plate structure 20 is in the closed position, the sensing element 32 is inserted into the sensing groove 31 to cut off the transmission path of the optically coupled signal. When the cover plate structure 20 is in the open position, the sensing element 32 is positioned outside the sensing groove 31, allowing smooth transmission of the optically coupled signal. The position of the cover plate structure 20 can be determined by determining whether the sensing arm 33 for receiving the optically coupled signal receives the optically coupled signal.

[0041] 3, 6, and 7, the incubation apparatus further includes a drive unit 40. The drive unit 40 includes a drive motor 41 provided below the mounting unit 10 and a power transmission structure 42 provided between the drive motor 41 and the rotating shaft 21. The power transmission structure 42 includes a first power transmission gear 421 fitted onto the output shaft of the drive motor 41, a second power transmission gear 422 fitted onto the rotating shaft 21, and a power transmission belt 423 wound around the first power transmission gear 421 and the second power transmission gear 422. Specifically, the drive motor 41 is a stepping motor, and by transmitting power via the first power transmission gear 421, the second power transmission gear 422, and the power transmission belt 423, the drive motor 41 can rotate the rotating shaft 21 and the translating plate 22 by a certain angle to switch the position of the cover plate structure 20, thereby providing the advantages of a simple structure and easy control. As shown in FIG. 5, the driving unit 40 further includes a motor frame 43, and the driving motor 41 is attached to the lower side of the placement unit 10 by the motor frame 43.

[0042] Of course, in embodiments not shown, the cover plate structure may be configured to be a structure that allows switching between the closed position and the open position by translation, for example, a rack and pinion structure or a screw nut structure may be used to translate the cover plate to seal the sealed loading area or to retract from the sealed loading area.

[0043] As shown in Figure 9, the present application further provides an incubation system, and an embodiment of the incubation system of the present application includes an incubation device and a reaction cup 1, the incubation device being the above-mentioned incubation device, and the reaction cup 1 having an upper opening 1001 and capable of being placed in the first mounting hole 11 or the second mounting hole 12. The above-mentioned incubation device can effectively solve the problem in the related art that items that are prone to volatilization or evaporation during the incubation process are incubated separately outside the reaction system, making the operation complicated, and therefore an incubation system including the above-mentioned incubation device also has the above-mentioned advantages.

[0044] Specifically, in this embodiment, the incubation device includes a plurality of first mounting holes 11 and a plurality of second mounting holes 12, and there are a plurality of reaction cups 1, at least some of which can be left in the first mounting holes 11, and the other reaction cups 1 can be left in the second mounting holes 12. Since the first mounting holes 11 and the second mounting holes 12 have the same structure, it is sufficient to prepare one type of reaction cup 1.

[0045] 9 and 10 , the reaction cup 1 includes a first cup body portion 1002, a second cup body portion 1003, and a support edge 1004. The first cup body portion 1002 is located below the second cup body portion 1003. An upper opening 1001 is formed in the second cup body portion 1003. The support edge 1004 is located at the boundary between the first cup body portion 1002 and the second cup body portion 1003 and extends outward. When the reaction cup 1 is placed in the first mounting hole 11, the upper surface of the open mounting area 101 is supported below the support edge 1004. When the reaction cup 1 is placed in the second mounting hole 12, the groove bottom wall of the gripping groove 16 is supported below the support edge 1004, and the second cup body portion 1003 is located in the gripping cavity 161.

[0046] The present application further provides a sample analyzer, and examples of the sample analyzer of the present application include the above-mentioned incubation device or the above-mentioned incubation system. Both the above-mentioned incubation device and the above-mentioned incubation system can effectively solve the problem in the related art that items that are prone to volatilization or evaporation during the incubation process are incubated separately outside the reaction system, making the operation complicated. Therefore, a sample analyzer having the above-mentioned incubation device or incubation system also has the above advantages.

[0047] In describing the present invention, the orientations or positional relationships supported by directional terms such as "front, rear, up, down, left, right," "lateral, longitudinal, vertical, horizontal," and "top, bottom" are generally based on the orientations or positional relationships shown in the drawings and are intended merely to facilitate and simplify the description of the present invention. Unless otherwise stated, these directional terms do not indicate or imply that the indicated devices or elements necessarily have a specific orientation or must be constructed and operated in a specific orientation, and therefore should not be understood to limit the scope of protection of the present invention. Directional terms such as "inside, outside" mean inside or outside relative to the contour of each member itself.

[0048] For convenience of description, spatially relative terms, such as "above," "above," "on top of," or "above," may be used to describe the spatial relationship of one device or feature shown in a figure to another. Note that spatially relative terms are intended to encompass devices being in different orientations than the illustrated orientation during use or operation. For example, if a device is inverted in a figure, a device described as being "above other devices or structures" or "on top of other devices or structures" would then be positioned "below other devices or structures" or "below other devices or structures." Thus, the exemplary term "above" includes both orientations: "above" and "below." The device may be positioned in other different ways (rotated 90 degrees or at other orientations) and still be described according to the spatially relative terms used herein.

[0049] It should be noted that the use of terms such as "first" and "second" to define parts is merely to facilitate the distinction between corresponding parts, and unless otherwise specified, the above terms have no special meaning and should not be understood as limiting the scope of protection of the present invention.

[0050] The above is only a preferred embodiment of the present invention, and is not intended to limit the present invention. Those skilled in the art can make various modifications and changes to the present invention. Any modifications, equivalent replacements, improvements, etc. made without departing from the spirit and principle of the present invention shall be included within the protection scope of the present invention. [Explanation of symbols]

[0051] 1: reaction cup, 1001: upper opening, 1002: first cup body, 1003: second cup body, 1004: support edge, 10: mounting portion, 101: open mounting area, 102: closed mounting area, 11: first mounting hole, 12: second mounting hole, 13: constant temperature member, 14: heating member, 15: heat insulation layer, 16: gripping groove, 161: gripping cavity, 17: partition plate, 181: temperature Sensor, 182: temperature control switch, 19: support member, 20: cover plate structure, 21: rotating shaft, 22: translating plate, 30: position sensing structure, 31: sensing groove, 32: sensing member, 33: sensing arm, 34: connecting arm, 40: drive unit, 41: drive motor, 42: power transmission structure, 421: first power transmission gear, 422: second power transmission gear, 423: power transmission belt, 43: motor frame

Claims

1. a mounting section (10) having an open mounting area (101) and a sealed mounting area (102), the open mounting area (101) being provided with a first mounting hole (11) and the sealed mounting area (102) being provided with a second mounting hole (12); a cover plate structure (20) that is provided in the sealed placement area (102), has an open position and a closed position, covers the sealed placement area (102) when in the closed position, and is retracted from the sealed placement area (102) to expose the second placement hole (12) when in the open position. An incubation device characterized by:

2. The sealed placement area (102) is provided with a gripping groove (16), The second mounting hole (12) is provided in the bottom wall of the gripping groove (16).

2. The incubation device according to claim 1 .

3. The structure of the second mounting hole (12) is similar to the structure of the first mounting hole (11), and / or The open mounting area (101) is provided with a plurality of the first mounting holes (11) arranged in a matrix, and / or The sealed mounting area (102) is provided with a plurality of the second mounting holes (12) arranged in a matrix, A plurality of partition plates (17) are provided in the gripping groove (16), The plurality of partition plates (17) partition the gripping groove (16) to form a plurality of gripping cavities (161) that are independent from each other; The plurality of gripping cavities (161) are provided to correspond one-to-one with the plurality of second mounting holes (12); The cross-sectional area of the gripping cavity (161) is larger than the cross-sectional area of the corresponding second mounting hole (12); The upper surface of the partition plate (17) is flush with the upper surface of the sealed placement area (102).

3. The incubation device according to claim 2, wherein the incubation device comprises:

4. When the reaction cup (1) is placed in the first mounting hole (11) and the cover plate structure (20) is in the closed position, the upper surface of the cover plate structure (20) is flush with or lower than the upper surface of the reaction cup (1).

2. The incubation device according to claim 1 .

5. The cover plate structure (20) includes a rotation shaft (21) drilled in the placement portion (10) and a translating plate (22) fixedly connected to the rotation shaft (21); The pivot shaft (21) pivots the pivot plate (22) to switch the cover plate structure (20) between the closed position and the open position.

2. The incubation device according to claim 1 .

6. Further comprising a position sensing structure (30) for detecting the position of the cover plate structure (20).

6. The incubation device according to claim 5, wherein the incubation device comprises:

7. The position sensing structure (30) includes a sensing groove (31) and a sensing member (32) provided on the rotation shaft (21); When the rotation shaft (21) is rotated, the sensing member (32) can be switched between a state in which it is inserted into the sensing groove (31) and a state in which it is positioned outside the sensing groove (31).

7. The incubation device according to claim 6, wherein the incubation device comprises:

8. further comprising a drive portion (40); The drive unit (40) includes a drive motor (41) provided below the placement unit (10) and a power transmission structure (42) provided between the drive motor (41) and the rotation shaft (21), The power transmission structure (42) includes a first power transmission gear (421) fitted onto the output shaft of the drive motor (41), a second power transmission gear (422) fitted onto the rotating shaft (21), and a power transmission belt (423) wound around the outside of the first power transmission gear (421) and the second power transmission gear (422).

6. The incubation device according to claim 5, wherein the incubation device comprises:

9. The placing section (10) includes a constant temperature member (13), a heating member (14), and a heat-retaining layer (15), The first mounting hole (11) and the second mounting hole (12) are both provided in the constant temperature member (13), The heating member (14) is provided adjacent to the constant temperature member (13) and can heat the constant temperature member (13) to 20°C to 50°C; The heat-retaining layer (15) covers the outer periphery and bottom of the constant temperature member (13) and the heating member (14).

2. The incubation device according to claim 1 .

10. An incubation system comprising an incubation device and a reaction cup (1), The incubation device is an incubation device according to any one of claims 1 to 9, The reaction cup (1) has an upper opening (1001) and can be placed in the first mounting hole (11) or the second mounting hole (12). An incubation system characterized by:

11. The incubation device according to any one of claims 1 to 9, A sample analysis device characterized by:

12. The incubation system of claim 10, A sample analysis device characterized by:

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