Medicine administration device

Abstract

To provide a medicine administration device capable of reducing energy required for driving a plunger while securing easiness of air bleeding of the inside of a syringe.SOLUTION: A medicine administration device 300 is a medicine administration device that administers a medicine to a living body. The medicine administration device 300 includes: a syringe holding part 31 that holds a syringe 110 while a spout 114 faces diagonally upward; and a plunger drive part 51 that moves a plunger 116 of the syringe 110 held by the syringe holding part 31 to diagonally upward to cause a content in the syringe 110 to be poured out.SELECTED DRAWING: Figure 1

Description

[Technical Field]

[0001] The present invention relates to a medication delivery device. [Background technology]

[0002] A drug administration device for administering a drug to a living body is described, for example, in Patent Document 1. In this drug administration device, a syringe is held so that the outlet faces vertically upward. [Prior art documents] [Patent documents]

[0003] [Patent Document 1] Special Publication No. 2020-532334 Summary of the Invention [Problem to be solved by the invention]

[0004] According to the investigations of the present inventors, there is room for improvement in the medicine injection device described in Patent Document 1 in terms of reducing the energy required to drive the plunger.

[0005] The present invention has been made in consideration of the above-mentioned problems, and provides a medicine injection device that can reduce the energy required to drive the plunger while ensuring ease of venting air from inside the syringe. [Means for solving the problem]

[0006] According to the present invention, there is provided a drug administration device for administering a drug to a living body, comprising: a syringe holder that holds the syringe with the injection outlet facing obliquely upward; a plunger driving unit that moves the plunger of the syringe held by the syringe holding unit obliquely upward to dispense the content of the syringe; A medication delivery device is provided comprising: [Effects of the Invention]

[0007] According to the present invention, it is possible to reduce the energy required to drive the plunger while ensuring ease of venting air from inside the syringe. [Brief explanation of the drawings]

[0008] [Figure 1] FIG. 1(a) is a side view of a medicine injection device according to a first embodiment, and FIG. 1(b) is a configuration diagram of the medicine injection device according to the first embodiment. [Figure 2] FIG. 10 is a front view of the main unit in the second embodiment, showing a state in which the first placement section is placed on the placement surface. [Figure 3] FIG. 10 is a side view of the main unit in the second embodiment, showing a state in which the first placement section is placed on the placement surface. [Figure 4] FIG. 10 is a front view of the main unit in the second embodiment, showing a state in which the second placement section is placed on the placement surface. [Figure 5] FIG. 10 is a side view of the main unit in the second embodiment, showing a state in which the second placement section is placed on the placement surface. [Figure 6] FIG. 10 is a configuration diagram of a medicine injection device according to a second embodiment. [Figure 7] Figures 7(a) and 7(b) are side views for explaining the inclination angle of the syringe in the second embodiment, where Figure 7(a) shows the state in which the first mounting portion is placed on the mounting surface, and Figure 7(b) shows the state in which the second mounting portion is placed on the mounting surface. [Figure 8] FIG. 10 is a front view of a medicine injection device according to a second embodiment. [Figure 9] 4 is a view of the main unit as viewed in the direction of arrow C shown in FIG. 3. [Figure 10] Figures 10(a) and 10(b) are diagrams showing the state in which an adapter is not attached to the syringe holding portion in the second embodiment, and of these, Figure 10(a) is a diagram of the main unit viewed in the direction of arrow C shown in Figure 3, and Figure 10(b) is a partially enlarged oblique view of the syringe holding portion and its surrounding structure. [Figure 11]11(a) and 11(b) are diagrams showing a state in which a syringe is attached to an adapter in the second embodiment, with FIG. 11(a) being a front view and FIG. 11(b) being a side view. [Figure 12] 12(a) and 12(b) are views showing a first adapter in the second embodiment, with FIG. 12(a) being a front view and FIG. 12(b) being a perspective view. [Figure 13] 13(a) and 13(b) are views showing a second adapter in the second embodiment, with FIG. 13(a) being a front view and FIG. 13(b) being a perspective view. [Figure 14] FIG. 10 is a block diagram of a medicine injection device according to a second embodiment. [Figure 15] FIG. 10 is a diagram showing a basic screen of a display unit in the second embodiment. [Figure 16] FIG. 16(a) is a diagram showing a state in which the display unit in the second embodiment displays candidate radiopharmaceuticals, and FIG. 16(b) is a diagram showing a state in which the display unit in the second embodiment displays candidate operating modes. [Figure 17] Figures 17(a) and 17(b) are side views for explaining the inclination angle of the syringe in a modified example of the second embodiment, where Figure 17(a) shows the state in which the first mounting portion is placed on the mounting surface, and Figure 17(b) shows the state in which the second mounting portion is placed on the mounting surface. [Figure 18] FIG. 10 is a configuration diagram of a medicine injection device according to a third embodiment. [Figure 19] FIG. 10 is a configuration diagram of a medicine injection device according to a first modified example of the third embodiment. [Figure 20] FIG. 13 is a front view of a medicine injection device according to a second modification of the third embodiment. DETAILED DESCRIPTION OF THE INVENTION

[0009] Hereinafter, each embodiment of the present invention will be described with reference to the drawings. In all the drawings, the same components are denoted by the same reference numerals, and the description thereof will be omitted as appropriate.

[0010] [First embodiment] First, the first embodiment will be described with reference to FIGS. 1(a) and 1(b). The drug administration device 300 according to this embodiment is a drug administration device that administers a drug to a living body. As shown in Figures 1(a) and 1(b), the drug administration device 300 includes a syringe holding unit 31 that holds the syringe 110 with the outlet 114 facing diagonally upward, and a plunger driving unit 51 (see, for example, Figure 14 of the second embodiment described below) that moves the plunger 116 of the syringe 110 held by the syringe holding unit 31 diagonally upward to eject the contents of the syringe 110.

[0011] According to this embodiment, syringe holding unit 31 holds syringe 110 with outlet 114 facing diagonally upward, which makes it easy to bleed air from inside syringe 110 (remove gas from inside syringe 110). Furthermore, because the contents are dispensed by moving plunger 116 of syringe 110 diagonally upward, the energy required to drive (move) plunger 116 can be reduced compared to moving it vertically upward. This allows for the miniaturization of plunger drive unit 51 (same as above), and therefore the miniaturization of medicine administration device 300.

[0012] More specifically, as shown in FIG. 1(b), in this embodiment, the drug administration device 300 has a flow path 76 connected to the syringe 110 (see also FIG. 6 of the second embodiment described below), and administers the drug from the syringe 110 to the living body via the flow path 76. The flow path 76 (see FIGS. 1(b) and 6) is, for example, configured by a flow path tube 71, which is a tube with an administration needle that connects the syringe 110 to a living body. The drug is administered transdermally via an administration needle 150 of the flow path tube 71, for example.

[0013] Second Embodiment Next, a second embodiment will be described with reference to FIGS. 2 to 16(b). The drug administration device 300 of this embodiment differs from the drug administration device 300 of the first embodiment described above in the points described below, but is otherwise configured in the same way as the drug administration device 300 of the first embodiment described above. In the following description, unless otherwise specified, the upper side of the paper in Figures 2 and 4 may be referred to as the top (upper side), and the opposite side (the lower side of the paper in Figures 2 and 4) may be referred to as the lower side or bottom side. Furthermore, the near side of the paper in Figures 3 and 4 may be referred to as the front side or front side (or front side), and the far side of the paper in Figures 3 and 4 may be referred to as the rear side or back side (or back side). Furthermore, the left side of the paper in Figures 2 and 4 may be referred to as the left (left side), and the right side of the paper in Figures 2 and 4 may be referred to as the right (right side). In the present invention, the positional relationships (upper and lower relationships, etc.) of the components of the drug injection device 300 are described with respect to the positional relationships when the first mounting section 16 of the drug injection device 300 is mounted on the mounting surface as shown in Figures 2 and 3, unless otherwise specified.

[0014] In this embodiment, the drug is, for example, a radioactive drug. More specifically, in this embodiment, the radiopharmaceutical is a radiopharmaceutical for SPECT (Single Photon Emission Computed Tomography) examination. That is, in this embodiment, pharmaceutical administration device 300 is a pharmaceutical administration device for SPECT examination. However, the present invention is not limited to this example, and the drug may be a non-radioactive drug. Furthermore, when the drug is a radioactive drug, the radioactive drug may be a radioactive drug containing a short-lived nuclide for PET (Positron Emission Tomography) examination or a radioactive drug for stress myocardial scintigraphy examination.

[0015] In this embodiment, as shown in FIGS. 2 and 3, pharmaceutical injection device 300 has syringe 111 and syringe 112 as syringe 110. Syringe 111 is a syringe for administering a radiopharmaceutical, and the radiopharmaceutical is stored in syringe 111 in advance. Syringe 112 is a syringe for physiological saline. Syringe 112 is used when transferring physiological saline from storage pack 74 (see FIG. 6) in which physiological saline is stored to flow path 76 (see FIG. 6). Note that storage pack 74 is suspended, for example, from a suspension stand (not shown).

[0016] The axial directions of the syringe 111 and the syringe 112 are aligned with each other. Each of syringe 111 and syringe 112 has a syringe body 115 having a liquid storage portion therein, and a plunger 116 slidably inserted into syringe body 115 . It should be noted that syringe 111 has a smaller capacity than syringe 112. For example, syringe 111 is a 5 mL syringe, and syringe 112 is a 20 mL or 30 mL syringe. In this embodiment, syringe 111, which is a syringe for administering a radiopharmaceutical, has a shielding cover part 118 (see FIG. 11(a)), and at least a part of syringe body 115 is covered by shielding cover part 118. At least a part of shielding cover part 118 is made of a material that shields radiation, such as tungsten or lead.

[0017] The plunger drive unit 51 (see Figure 14) has a plunger drive motor 81 (see Figure 14) and a drive transmission mechanism (not shown) that transmits the drive force of the plunger drive motor 81 to the plunger gripping unit 41 (and thus the plunger 116), and is configured so that the plunger gripping unit 41 and the plunger 116 can be moved by driving the plunger drive motor 81. More specifically, the plunger driving unit 51 performs the operation of pulling out the plunger 116 from the syringe body 115 by moving the plunger gripping unit 41 in the pulling-out direction, and the operation of pushing the plunger 116 into the syringe body 115 by moving the plunger gripping unit 41 in the pushing-in direction. Here, the "pulling out direction" is the opposite side of the outlet 114 in the axial direction of the syringe 110, and the "pushing in direction" is the side of the outlet 114 in the axial direction of the syringe 110. In this embodiment, as shown in Figures 2, 4 and 9, the drug administration device 300 has, as plunger gripping portion 41, plunger gripping portion 42 that grips plunger 116 of syringe 111 and plunger gripping portion 43 that grips plunger 116 of syringe 112. Similarly, medicine injection device 300 has, as plunger driver 51, plunger driver 52 (see FIG. 14) that drives plunger 116 of syringe 111, and plunger driver 53 (see FIG. 14) that drives plunger 116 of syringe 112. Furthermore, medicine injection device 300 has, as plunger drive motor 81, plunger drive motor 82 (see FIG. 14) that moves plunger gripping portion 42, and plunger drive motor 83 (see FIG. 14) that moves plunger gripping portion 43. In the present invention, the actuator of the plunger driving portion 51 is not limited to a motor (plunger driving motor 81), but may be a cylinder or the like.

[0018] In this embodiment, the flow path 76 connected to the syringe 110 includes an administration flow path 77 that interconnects the syringe body 115 of the syringe 111 with the inside of the living body, and a saline flow path 78 that interconnects the syringe body 115 of the syringe 112 with the storage pack 74. When the radiopharmaceutical is administered to a living body, the radiopharmaceutical flows through the administration flow path 77 and is injected into the living body from the syringe 111 . When saline is aspirated from the storage pack 74 , the saline flows through the saline flow path 78 and from the storage pack 74 into the syringe 112 .

[0019] Furthermore, in this embodiment, drug administration device 300 is provided with a switching mechanism that switches flow path 76. The switching mechanism is made up of three-way stopcock 60 and three-way stopcock drive unit 56 (see FIG. 14) that drives three-way stopcock 60. By rotating three-way stopcock 60, the switching mechanism can switch between a state in which the inside of syringe body 115 and the outside of syringe body 115 (other flow paths, containers, etc.) are mutually connected, and a state in which the inside of syringe body 115 and the outside of syringe body 115 (other flow paths, containers, etc.) are mutually blocked. As shown in FIG. 14, the three-way stopcock drive unit 56 has a three-way stopcock drive motor 86, and is configured so that the three-way stopcock 60 can be rotated by driving the three-way stopcock drive motor 86. More specifically, drug administration device 300 has, as three-way stopcock 60, a first three-way stopcock 61 directly connected to syringe 111 and a second three-way stopcock 62 directly connected to syringe 112. First three-way stopcock 61 and second three-way stopcock 62 are directly connected to each other. In addition, the drug administration device 300 has a three-way stopcock holding section 46 that holds the three-way stopcock 60, which includes a first three-way stopcock holding section 47 that holds the first three-way stopcock 61 and a second three-way stopcock holding section 48 that holds the second three-way stopcock 62. In addition, the drug administration device 300 has a three-way stopcock drive unit 56, which includes a first three-way stopcock drive unit 57 that rotates the first three-way stopcock 61 individually, and a second three-way stopcock drive unit 58 that rotates the second three-way stopcock 62 individually. The drug administration device 300 also has three-way stopcock drive motors 86, including a first three-way stopcock drive motor 87 that rotates the first three-way stopcock 61 and a second three-way stopcock drive motor 88 that rotates the second three-way stopcock 62. In the present invention, drug administration device 300 does not have three-way stopcock drive unit 56, and three-way stopcock 60 may be switched manually.

[0020] Furthermore, as shown in Figure 6, the medicine administration device 300 is provided with a plurality of flow path tubes 71 that form a flow path 76. Note that the plurality of flow path tubes 71 and the storage pack 74 are not shown in Figures 2 to 5 and 7(a) to 10(b). More specifically, the plurality of flow path tubes 71 include, for example, a first flow path tube 72 and a second flow path tube 73. In this embodiment, the first three-way stopcock 61, the first flow path tube 72, and the administration needle 150 constitute the administration flow path 77. More specifically, the first flow path tube 72 connects the syringe 111 to the living body and is a tube with an administration needle. One end of the first flow path tube 72 is connected to the outlet 114 of the syringe 111 via the first three-way stopcock 61, and the other end of the first flow path tube 72 is provided with an administration needle 150 that is inserted into the living body. The radiopharmaceutical is administered transcutaneously to the living body via the administration needle 150. In the present embodiment, the second flow path tube 73 and the second three-way stopcock 62 constitute a saline flow path 78. More specifically, the second flow path tube 73 connects the storage pack 74 and the syringe 112. One end of the second flow path tube 73 is connected to the storage pack 74, and the other end of the second flow path tube 73 is connected to the outlet 114 of the syringe 112 via the second three-way stopcock 62. Furthermore, in this embodiment, an air vent filter 79 is provided between the first three-way stopcock 61 and the first flow path tube 72. This allows gas (air) in the flow path 76 to be removed as it passes through the air vent filter 79. Therefore, it is possible to administer contents (saline solution or radiopharmaceutical) that are substantially free of air to a living body. It should be noted that in the present invention, the number of flow path tubes 71 included in the drug administration device 300 is not limited to this example. That is, the administration flow path 77 may be configured to include a flow path tube 71 other than the first flow path tube 72. Similarly, the saline flow path 78 may be configured to include a flow path tube 71 other than the second flow path tube 73.

[0021] As shown in FIGS. 3 and 5, the medicine administration device 300 includes a base portion 10 that is placed on a horizontal placement surface 400. The syringe holder 31 (the syringe holder 33 and the syringe holder 36) and the plunger driver 51 (the plunger driver 52 and the plunger driver 53) are mounted on the base 10. Furthermore, the base portion 10 has a first placement portion 16 and a second placement portion 17 that can be placed on the placement surface 400, respectively. As shown in FIG. 3, when the first mounting portion 16 is placed on the mounting surface 400, the syringe holding portion 31 holds the syringe 110 with the outlet 114 facing diagonally upward, and the plunger driving portion 51 moves the plunger 116 of the syringe 110 held by the syringe holding portion 31 diagonally upward to dispense the contents of the syringe 110. As shown in Figure 5, when second mounting portion 17 is placed on mounting surface 400, syringe holding portion 31 holds syringe 110 with outlet 114 facing diagonally downward, and plunger driving portion 51 moves plunger 116 of syringe 110 held by syringe holding portion 31 diagonally downward to dispense the contents of syringe 110.

[0022] With this configuration, the attitude of syringe 110 can be switched as needed between an attitude in which spout 114 faces obliquely upward (see FIG. 3) and an attitude in which spout 114 faces obliquely downward (see FIG. 5). More specifically, for example, when the use of the air vent filter 79 is not desired from the viewpoint of achieving a more inexpensive configuration, the orientation of the outlet 114 facing obliquely upward is selected. This facilitates deairing (removal of gas from inside the syringe 110) from inside the syringe 110, and thus allows for administration of substantially air-free contents (such as physiological saline or a radiopharmaceutical) to a living body without using the air vent filter 79. On the other hand, for example, when it is desired to aspirate contents using the syringe 110 from another container (not shown) or when it is desired to minimize the energy required to drive (move) the plunger 116 during extraction from the syringe 110, it is possible to select the orientation of the outlet 114 facing obliquely downward. Furthermore, since the height position of the administration flow path 77 changes depending on the orientation of the outlet 114, either the orientation of the outlet 114 facing obliquely upward or the orientation of the outlet 114 facing obliquely downward can be selected depending on the height relationship between the living body (e.g., a living body lying on a bed) and the placement surface 400.

[0023] Furthermore, the first inclination angle α (Figure 7(a)), which is the inclination angle of the syringe 110 held by the syringe holding portion 31 when the first mounting portion 16 is placed on the mounting surface 400, and the second inclination angle β (Figure 7(b)), which is the inclination angle of the syringe 110 held by the syringe holding portion 31 when the second mounting portion 17 is placed on the mounting surface 400, are different from each other. With this configuration, the inclination angle of the syringe 110 can be changed when the first mounting portion 16 is placed on the mounting surface 400 and when the second mounting portion 17 is placed on the mounting surface 400, so that it is possible to select the inclination angle of the syringe 110 that provides better operability and visibility depending on the posture of the user (radiologist, etc.). The "tilt angle of syringe 110" here refers to the angle between the axis of syringe 110 and mounting surface 400. Also, dashed two-dot lines 410 and 420 shown in Figures 7(a) and 7(b) are imaginary straight lines passing through the axis of syringe 110.

[0024] Second inclination angle β is preferably smaller than first inclination angle α, for example. By doing so, when second mounting portion 17 is placed on mounting surface 400, front panel 12 is inclined so as to be closer to mounting surface 400 (at an inclination angle closer to horizontal), so that syringe 110 can be easily attached to syringe holding portion 31 of front panel 12. More specifically, the first tilt angle α is preferably, for example, not less than 30 degrees and not more than 75 degrees, and more preferably 60 degrees. The second tilt angle β is, for example, preferably 10 degrees or more and 50 degrees or less, and more preferably 20 degrees or more and 40 degrees or less. However, the present invention is not limited to this example, and the first inclination angle α and the second inclination angle β may be equal to each other, as in a modified example of the second embodiment described later, or the first inclination angle α may be smaller than the second inclination angle β.

[0025] More specifically, the medicine administration device 300 includes a portable main unit 100 that is placed on a horizontal placement surface 400. The main unit 100 includes the base portion 10 described above. The base portion 10 includes, for example, a housing 20 and a support portion 15 that supports the housing 20 so that it can stand on its own. Housing 20 is provided with syringe holding portion 31, plunger gripping portion 41, three-way stopcock holding portion 46, plunger driving portion 51, and three-way stopcock driving portion 56. More specifically, inside housing 20, for example, plunger driving motor 81 and three-way stopcock driving motor 86 are arranged. 2 and other figures, an air vent filter 79 and a connector 75a are attached to the first three-way stopcock 61, and a connector 75b is attached to the second three-way stopcock 62. The first three-way stopcock 61 is connected to a flow path tube 71 (e.g., first flow path tube 72) that constitutes the administration flow path 77 via the connector 75a. Similarly, the second three-way stopcock 62 is connected to a flow path tube 71 (e.g., second flow path tube 73) that constitutes the physiological saline flow path 78 via the connector 75b.

[0026] As shown in Figures 2 to 4, the housing 20 is formed in an approximately rectangular parallelepiped shape and has six planar portions: a front portion 23, a back portion 24, a pair of side portions 25, a first planar portion 21, and a second planar portion 22. Each of the front surface portion 23, the back surface portion 24, the pair of side surface portions 25, the first planar portion 21 and the second planar portion 22 is formed in a substantially flat plate shape. 2 and 4, in the present embodiment, in a side view, the housing 20 is supported by the support portion 15 so as to be able to stand on its own, with the front portion 23 and the back portion 24 each inclined in a direction gradually moving away from the mounting surface 400 as they extend rearward. In addition, the axial direction of the syringe 110 mounted on the base portion 10 also inclined in a direction gradually moving away from the mounting surface 400 as they extend rearward. The front surface portion 23 and the rear surface portion 24 are arranged parallel to and facing each other in a direction that includes a front-to-rear component. The front surface portion 23 forms the front side of the base portion 10, and the rear surface portion 24 forms the rear side of the base portion 10. The plate surface of the front surface portion 23 is perpendicular to the plate surfaces of the first planar portion 21, the second planar portion 22, and the pair of side surface portions 25. Similarly, the plate surface of the rear surface portion 24 is perpendicular to the plate surfaces of the first planar portion 21, the second planar portion 22, and the pair of side surface portions 25. The pair of side surface portions 25 are arranged parallel to and facing each other in a direction including a left-right component. Of the pair of side surface portions 25, one side surface portion 25 constitutes one side surface side of the base portion 10, and the other side surface portion 25 constitutes the other side surface side of the base portion 10. The first planar portion 21 and the second planar portion 22 are arranged parallel to and facing each other in a direction that includes a vertical component. When the first mounting portion 16 is placed on the mounting surface 400, the first planar portion 21 forms the top surface of the base portion 10, and the second planar portion 22 forms the bottom surface of the base portion 10. On the other hand, when the second mounting portion 17 is placed on the mounting surface 400, the second planar portion 22 forms the top surface of the base portion 10, and the first planar portion 21 forms the bottom surface of the base portion 10.

[0027] 3 and 5, the support portion 15 is formed, for example, in a substantially flat plate shape. The support portion 15 is formed, for example, at the end of the back surface portion 24 on the second planar portion 22 side. More specifically, the support portion 15 gradually protrudes in a direction away from the back surface portion 24 as it approaches the first planar portion 21 side. The plate surface of the support portion 15 is arranged facing a direction that includes both a component in the opposing direction between the front portion 23 and the back portion 24 and a component in the opposing direction between the first planar portion 21 and the second planar portion 22.

[0028] In this embodiment, the surface of the support portion 15 opposite to the rear surface portion 24 is formed flat, and this opposite surface constitutes the first mounting portion 16. More specifically, in this embodiment, the state in which the first mounting portion 16 is mounted on the mounting surface 400 means that the surface of the support portion 15 opposite to the rear surface portion 24 is mounted on the mounting surface 400. In this state, the first planar portion 21 is located at the top and constitutes the top surface of the base portion 10, and the second planar portion 22 is located at the bottom and constitutes the bottom surface of the base portion 10. As shown in FIG. 2, the syringe 111 is located on the left side of the base portion 10, and the syringe 112 is located on the right side of the base portion 10. The syringes 111 and 112 are positioned such that their respective spouts 114 are open rearward and obliquely upward (in the direction of arrow A shown in FIG. 3). The direction in which plunger 116 is pushed when dispensing the contents is the direction of arrow A shown in FIG.

[0029] Furthermore, the end face of the support portion 15 opposite to the side connected to the back surface portion 24 is formed flat, and this opposite end face constitutes a part of the second mounting portion 17. More specifically, in the present embodiment, the second mounting portion 17 is constituted by the opposite end face of the support portion 15 and a corner portion 26 at the boundary between the first planar portion 21 and the back surface portion 24. The state in which the second mounting portion 17 is placed on the mounting surface 400 is a state in which the opposite end face of the support portion 15 and the corner portion 26 at the boundary between the first planar portion 21 and the back surface portion 24 are each placed on the mounting surface 400. In this state, the first planar portion 21 is located downward and constitutes the bottom surface side of the base portion 10, and the second planar portion 22 is located upward and constitutes the top surface side of the base portion 10. 4, syringe 111 is located on the right side of base part 10, and syringe 112 is located on the left side of base part 10. Furthermore, syringes 111 and 112 are in a position where their respective outlets 114 are open forward and obliquely downward (in the direction of arrow B shown in FIG. 5). The direction in which plunger 116 is pushed when dispensing the contents is the direction of arrow B shown in FIG. 5.

[0030] Furthermore, in this embodiment, the base portion 10 has, for example, a front panel 12 , and the syringe holding portion 31 holds the syringe 110 along the front panel 12 . More specifically, the front panel 12 is, for example, a portion of the front surface portion 23 that protrudes forward more than other portions of the front surface portion 23. The front panel 12 is provided with a syringe holder 31, a plunger grip 41, a three-way stopcock 60, and a three-way stopcock holder 46. Furthermore, as shown in FIGS. 2 and 3, the front panel 12 is provided with a cover portion 13 that covers the front side of the three-way stopcock 60 in an openable and closable manner.

[0031] The weight of the main unit 100 is preferably, for example, 50 kg or less. That is, the main unit 100 is portable, and its weight is such that the user can carry it by hand. Furthermore, the position of the main unit 100 can be easily switched manually between a state in which the first placement section 16 is placed on the placement surface 400 and a state in which the second placement section 17 is placed on the placement surface 400. In this embodiment, the weight of the main unit 100 is, for example, more preferably 1 kg or more and 30 kg or less, and even more preferably 5 kg or more and 15 kg or less.

[0032] In this embodiment, the syringe 110 can be attached to and detached from the syringe holding portion 31 from the front side of the front panel 12. Furthermore, the second inclination angle β, which is the inclination angle of the syringe 110 held by the syringe holding portion 31 when the second mounting portion 17 is placed on the mounting surface 400, is smaller than the first inclination angle α, which is the inclination angle of the syringe 110 held by the syringe holding portion 31 when the first mounting portion 16 is placed on the mounting surface 400. With this configuration, the inclination angle β of syringe 110 when second mounting unit 17 is placed on mounting surface 400 is smaller than the inclination angle α of syringe 110 when first mounting unit 16 is placed on mounting surface 400. Therefore, when second mounting unit 17 is placed on mounting surface 400, the user (radiologist, etc.) can easily attach and detach syringe 110 to and from syringe holding unit 31 while standing, with medicine injection device 300 placed on desk 280 (see FIG. 8 ).

[0033] In this embodiment, a detachable adapter 120 can be attached to the syringe holding portion 31. The syringe 110 is attached to the syringe holder 31 via an adapter 120 . The adapter 120 and the syringe holding unit 31 will be described in more detail below. When describing the positional relationship (upper-lower relationship, etc.) of the components of the adapter 120 and the syringe holding unit 31, the upper side of the paper in FIGS. 9 and 10(a) may be referred to as the top (upper side), and the opposite side (the lower side of the paper in FIGS. 9 and 10(a)) may be referred to as the bottom or lower side. Furthermore, the near side of the paper in FIGS. 9 and 10(a) may be referred to as the front or front side (or front side), and the far side of the paper in FIGS. 9 and 10(a) may be referred to as the rear or rear side (or rear side). Furthermore, the left side of the paper in FIGS. 9 and 10(a) may be referred to as the left (left side), and the right side of the paper in FIGS. 9 and 10(a) may be referred to as the right (right side). 9 is a view of main unit 100 viewed from the front side of front panel 12 (the direction of arrow C shown in FIG. 3) in the normal direction of front panel 12. When attaching adapter 120 to syringe holding portion 31, adapter 120 is attached to syringe holding portion 31 from the direction of arrow C.

[0034] 9, in this embodiment, syringe holding portion 31 includes three plate-shaped portions (first plate-shaped portion 32a, second plate-shaped portion 32b, and third plate-shaped portion 32c) provided on the front surface (front face) of front panel 12. These three plate-shaped portions are arranged side by side from the left in the order of first plate-shaped portion 32a, second plate-shaped portion 32b, and third plate-shaped portion 32c. Each of the first to third plate-shaped portions 32a to 32c is formed in a substantially flat plate shape. The plate surfaces of each of the first to third plate-shaped portions 32a to 32c are arranged facing the left-right direction. More specifically, the first plate-shaped portion 32a and the second plate-shaped portion 32b are arranged parallel to and facing each other in the left-right direction. Similarly, the second plate-shaped portion 32b and the third plate-shaped portion 32c are arranged parallel to and facing each other in the left-right direction. In this embodiment, the first plate-shaped portion 32a and the second plate-shaped portion 32b form a syringe holding portion 33, and the second plate-shaped portion 32b and the third plate-shaped portion 32c form a syringe holding portion 36. More specifically, the space between the first plate-shaped portion 32a and the second plate-shaped portion 32b constitutes a storage area in which the syringe 111 is stored, and the space between the second plate-shaped portion 32b and the third plate-shaped portion 32c constitutes a storage area in which the syringe 112 is stored.

[0035] As shown in Figures 11(a) to 13(b), the adapter 120 includes a main body portion 125 and three bifurcated holding portions (a first bifurcated holding portion 126, a second bifurcated holding portion 127, and a third bifurcated holding portion 128) that protrude from the main body portion 125 in two directions. The main body 125 is formed in the shape of a flat plate that is long in the vertical direction. The first to third bifurcated holding portions 126 to 128 are each formed on the front surface of the main body portion 125. The first to third bifurcated holding portions 126 to 128 are arranged side by side from above in the order of first bifurcated holding portion 126, second bifurcated holding portion 127, and third bifurcated holding portion 128. Each of the first to third bifurcated holding portions 126 to 128 is formed, for example, in the shape of a flat plate that protrudes from the front surface of the main body portion 125 in a direction perpendicular to the plate surface of the main body portion 125. Each of the first to third bifurcated holding portions 126 to 128 has cutout-shaped portions 126a, 127a, and 128a that penetrate each of the first to third bifurcated holding portions 126 to 128 in the thickness direction. The cutout-shaped portions 126a to 128a are open toward the front. In this way, each of the first to third bifurcated holding portions 126 to 128 is formed in a bifurcated shape that is open toward the front.

[0036] In this embodiment, when attaching syringe 110 to adapter 120, syringe body 115 of syringe 110 is inserted into notched portions 126a to 128a of first to third bifurcated holding portion 126 to 128 from the front. 11(a) and 11(b), the syringe body 115 of the syringe 110 engages with the notched portions 126a to 128a of the first to third bifurcated holding portions 126 to 128, respectively, whereby the syringe body 115 is sandwiched between the first to third bifurcated holding portions 126 to 128. In this way, the syringe 110 is detachably attached to the adapter 120. In syringe body 115, a portion of syringe body 115 closer to spout 114 than flange portion 115a is sandwiched between first bifurcated holding portion 126 and second bifurcated holding portion 127, and a portion of syringe body 115 closer to plunger 116 than flange portion 115a is sandwiched by third bifurcated holding portion 128. Furthermore, flange portion 115a of syringe body 115 is sandwiched vertically between second bifurcated holding portion 127 and third bifurcated holding portion 128.

[0037] 9 and other figures, in this embodiment, a detachable adapter 120 can be attached to the syringe holding portion 33. Of the syringes 111 and 112, the syringe 111 is attached to the syringe holding portion 33 via the adapter 120. Furthermore, as the adapter 120, a plurality of types of adapters 120 corresponding to syringes 111 of a plurality of types of shapes or sizes can be interchangeably attached to the syringe holding portion 33. 9, adapter 120 is housed between first plate-shaped portion 32a and second plate-shaped portion 32b, for example, with syringe 111 held therein. The width dimension of main body 125 of adapter 120 in the left-right direction is set to be substantially the same as the distance between the opposing surfaces of first plate-shaped portion 32a and second plate-shaped portion 32b. Therefore, adapter 120 is attached to syringe holding portion 33 with main body 125 sandwiched between first plate-shaped portion 32a and second plate-shaped portion 32b. Furthermore, in this embodiment, an insertion groove 37 is formed on each of the opposing surfaces of the first plate-shaped portion 32a (the opposing surface facing the second plate-shaped portion 32b) and the opposing surface of the second plate-shaped portion 32b (the opposing surface facing the first plate-shaped portion 32a), and the adapter 120 is formed with a pair of protrusions 129 that are inserted into each of the insertion grooves 37 of the first plate-shaped portion 32a and the second plate-shaped portion 32b. One of the pair of protrusions 129 is inserted into the insertion groove 37 formed in the first plate-shaped portion 32a, and the other of the pair of protrusions 129 is inserted into the insertion groove 37 formed in the second plate-shaped portion 32b. In this way, the adapter 120 and therefore the syringe 111 are securely held between the first plate-shaped portion 32a and the second plate-shaped portion 32b.

[0038] The pair of protrusions 129 have, for example, the same shape and are arranged symmetrically. More specifically, as shown in Figures 12(a) and 12(b), of the pair of protrusions 129, one protrusion 129 protrudes leftward from the left side surface of the adapter 120, and the other protrusion 129 protrudes rightward from the right side surface of the adapter 120. The insertion grooves 37 formed in the first plate-shaped portion 32a and the insertion grooves 37 formed in the second plate-shaped portion 32b are, for example, identical in shape and arranged symmetrically. 10(a) and 10(b), the insertion groove 37 formed in the first plate-shaped portion 32a is recessed leftward from the opposing surface (same as above) of the first plate-shaped portion 32a. The insertion groove 37 includes a first portion 37a extending linearly in the front-rear direction and a second portion 37b extending linearly upward from the rear end of the first portion 37a. The front end of the first portion 37a opens at the front end surface of the first plate-shaped portion 32a. Similarly, the insertion groove 37 formed in the second plate-shaped portion 32b is recessed rightward from the opposing surface (same as above) of the second plate-shaped portion 32b. The insertion groove 37 includes the first portion 37a and the second portion 37b. The front end of the first portion 37a opens at the front end surface of the second plate-shaped portion 32b.

[0039] When one of the protrusions 129 is inserted into the insertion groove 37 formed in the first plate-shaped portion 32a, the protrusion 129 is inserted into the insertion groove 37 from the front end of the first portion 37a and then further inserted rearward along the first portion 37a. The protrusion 129 is then engaged with the end of the second portion 37b on the first three-way stopcock 61 side (same as above). Similarly, when the other protrusion 129 is inserted into the insertion groove 37 formed in the second plate-shaped portion 32b, the protrusion 129 is inserted rearward along the first portion 37a and then engaged with the upper end of the second portion 37b. As a result, as shown in FIG. 9, with the spout 114 of the syringe 111 connected to the first three-way stopcock 61, the adapter 120 is detachably attached to the syringe holding portion 33. When removing adapter 120 from syringe holding portion 33, protrusions 129 are moved downward along second portions 37b of the corresponding insertion grooves 37. Next, protrusions 129 are further moved forward along first portions 37a and removed from the front ends of first portions 37a. This allows the pair of protrusions 129, and therefore adapter 120 and syringe 111, to be removed from insertion grooves 37.

[0040] In this embodiment, a plurality of types of adapters 120 corresponding to syringes 110 of a plurality of shapes or sizes can be interchangeably attached to syringe holding portion 31. This configuration makes it easy to use syringes 110 of a variety of shapes or sizes depending on the type and dosage of the drug to be administered.

[0041] More specifically, the drug administration device 300 has, as adapters 120, a first adapter 121 that corresponds to the syringe 111 of this embodiment, and a second adapter 122 that corresponds to a syringe (not shown) for administering a radioactive drug that has a shape or dimensions different from that of the syringe 111. Furthermore, the medicine injection device 300 has, as insertion grooves 37, a first insertion groove 371 into which the pair of protrusions 129 of the first adaptor 121 are inserted, and a second insertion groove 372 into which the pair of protrusions 129 of the second adaptor 122 are inserted.

[0042] In the present embodiment, for example, the first adaptor 121 and the second adaptor 122 differ from each other in the points described below, but are otherwise configured similarly to each other. The dimensions of each portion of second adaptor 122 are set to correspond to the dimensions of a syringe for administering a radiopharmaceutical that has a shape or dimensions different from those of syringe 111. More specifically, the maximum opening width of notched portion 128a of third bifurcated holding portion 128 of first adaptor 121 is smaller than the maximum opening width of notched portion 128a of third bifurcated holding portion 128 of second adaptor 122. This allows a syringe in which the dimensions of the portion of syringe body 115 on the plunger 116 side relative to flange portion 115a are set larger than those of syringe 111 to be favorably attached to second adaptor 122. 12(a) and 12(b), in the first adapter 121, the pair of protrusions 129 protrude from the right and left sides of the second bifurcated holding part 127, respectively. On the other hand, as shown in FIGS. 13(a) and 13(b), in the second adapter 122, the pair of protrusions 129 protrude from the right and left sides of the boundary between the main body 125 and the third bifurcated holding part 128, respectively. That is, in the up-down direction, the position of the pair of protrusions 129 in the first adapter 121 is higher than the position of the pair of protrusions 129 in the second adapter 122. In addition, in the front-rear direction, the position of the pair of protrusions 129 in the first adapter 121 is more forward than the position of the pair of protrusions 129 in the second adapter 122.

[0043] Similarly, in the case of this embodiment, as an example, the first insertion groove 371 and the second insertion groove 372 differ from each other in the points described below, but are otherwise configured similarly to each other. 10(b), the length dimension (dimension in the front-rear direction) of first portion 37a of second insertion groove 372 is greater than the length dimension of first portion 37a of first insertion groove 371. Second portion 37b of second insertion groove 372 is disposed rearward of second portion 37b of first insertion groove 371. Also, as described above, the positions of pair of protrusions 129 of first adapter 121 are forward of the positions of pair of protrusions 129 of second adapter 122 in the front-rear direction. This allows the attachment position of first adapter 121 relative to syringe holding portion 31 and the attachment position of second adapter 122 relative to syringe holding portion 31 to be aligned in the front-rear direction. 10(a), first insertion groove 371 is disposed above second insertion groove 372 in the vertical direction. As described above, the positions of pair of protrusions 129 on first adapter 121 are higher in the vertical direction than the positions of pair of protrusions 129 on second adapter 122. This allows the attachment position of first adapter 121 relative to syringe holding portion 31 and the attachment position of second adapter 122 relative to syringe holding portion 31 to be aligned in the vertical direction.

[0044] The present invention is not limited to the above example, and the shapes and dimensions of first adaptor 121 and second adaptor 122 can be set as appropriate according to the shapes and dimensions of the corresponding syringes. That is, for example, the length dimension of main body 125 of first adaptor 121 and the length dimension of main body 125 of second adaptor 122 may be different from each other, and the number of bifurcated holding portions of first adaptor 121 and the number of bifurcated holding portions of second adaptor 122 may be different from each other. Furthermore, in the present invention, the number (type) of adapters 120 included in medicine injection device 300 is not limited to the above example, and can be set appropriately depending on the number (type) of corresponding syringes 110. In the present invention, both syringe 111 and syringe 112 may be replaceably attachable to syringe holder 31 (syringe holder 33 and syringe holder 36) via corresponding adapters 120, respectively.

[0045] Furthermore, as shown in FIG. 14, the drug injection device 300 includes, for example, a display unit 220 that performs display operations, an operation unit 230 that accepts operations from the user, and a control unit 250 that controls the operation of the drug injection device 300, including controlling the display operation of the display unit 220 and the operation of the plunger drive unit 51, in accordance with operations on the operation unit 230. When the control unit 250 receives a predetermined trigger, it causes the display unit 220 to display candidates for multiple types of examination. When an examination mode is selected from the candidate display showing candidates for multiple types of examination modes displayed on the display unit 220 by operating the operation unit 230, the control unit 250 causes the plunger driving unit 51 to operate in the operation mode corresponding to the selected examination mode. With this configuration, the radiopharmaceutical can be automatically administered from the syringe. More specifically, for example, compared to manually administering a radiopharmaceutical from a syringe, the speed at which plunger 116 is withdrawn can be kept constant, so the radiopharmaceutical can be administered to a living body while maintaining a constant flow rate. Furthermore, by adjusting the moving speed of plunger driver 51 (i.e., the withdrawal speed of plunger 116), the administration rate of the radiopharmaceutical can also be adjusted. Furthermore, when the control unit 250 receives a predetermined trigger, it causes the display unit 220 to display candidates for multiple types of tests, so that the correct test mode and operation mode can be set more reliably than when the test mode and corresponding operation mode are set manually. In the case of this embodiment, the "predetermined trigger" here is typically an input operation performed by the user on the operation unit 230 (for example, selection of "administration mode selection" displayed on the basic screen (described in detail later) of the display unit 220). However, the present invention is not limited to this example, and the "predetermined trigger" may also be reading a barcode (identification code) printed on a container containing a radiopharmaceutical to be administered by the barcode reader 235 (described in detail later), and inputting the information obtained by the reading into the control unit 250. Furthermore, the present invention may be configured so that the user manually sets the inspection mode and the corresponding operation mode.

[0046] More specifically, in addition to the main unit 100, the medicine injection device 300 further includes an operation terminal 200 having a display unit 220, an operation unit 230, and a control unit 250, for example. The operation terminal 200 is, for example, a notebook computer, and includes a housing 210 having a liquid crystal display panel 221 and a keyboard 233, a mouse 232, and a barcode reader 235. A control unit 250 is also built into the housing 210. In this embodiment, the liquid crystal display panel 221 is the display unit 220. The keyboard 233, the mouse 232, and the barcode reader 235 constitute the operation unit 230. Furthermore, the operation terminal 200 includes, for example, a storage unit 240 (see FIG. 14). The storage unit 240 stores and holds multiple (for example, up to 300) administration histories (including administration information). This allows the user to check the administration history via the operation terminal 200 and print out desired administration information using a printer (not shown). The present invention is not limited to the above example, and the operation terminal 200 may be, for example, a desktop personal computer. Also, in the present invention, the liquid crystal display panel 221 may be a touch panel type, and the display unit 220 may also function as the control unit 250.

[0047] As shown in FIG. 14, the control unit 250 is configured to include a CPU (Central Processing Unit) 251 that executes control operations in accordance with a control program, a ROM (Read Only Memory) 252 that stores and holds the control program (program), and a RAM (Random Access Memory) 253 that functions as a working area for the CPU 251, etc. The control unit 250 controls the operation of each component included in the main unit 100. More specifically, in this embodiment, the operation terminal 200 is electrically connected to the main unit 100 via a connection cable (USB cable) (not shown). In this embodiment, the control unit 250 controls the operation of each of the plunger drive motor 81 (plunger drive motor 82 and plunger drive motor 83) and the three-way stopcock drive motor 86 (first three-way stopcock drive motor 87 and second three-way stopcock drive motor 88) via the main unit control unit 90, for example, by transmitting a control signal to the main unit control unit 90 included in the main unit 100. The control unit 250 controls the operation of the plunger drive motor 81, causing the plunger 116 to move up and down. The control unit 250 controls the operation of the three-way stopcock drive motor 86, causing the three-way stopcock 60 to rotate and switch the three-way stopcock 60. In the present invention, drug injection device 300 does not necessarily have to include operation terminal 200, and for example, main unit 100 may be equipped with display unit 220 and operation unit 230. In this case, when main unit-side controller 90 receives a predetermined trigger, it causes display unit 220 to display candidates for multiple types of tests, and when one of the test modes is selected, main unit-side controller 90 operates plunger driver 51 and three-way stopcock driver 56 in the operation mode corresponding to the selected test mode.

[0048] In this embodiment, the control unit 250 can obtain information such as the type of radiopharmaceutical, product code, expiration date, manufacturing lot number, manufacturing location, manufacturing date, etc., by reading a barcode (not shown) printed on a container of the radiopharmaceutical to be administered with the barcode reader 235. Note that in the present invention, information on the radiopharmaceutical may be input to the control unit 250 by, for example, an input operation on the operation unit 230 (for example, the mouse 232 or the keyboard 233) other than the barcode reader 235. Furthermore, the control unit 250 can acquire information about the subject, such as the subject's name, date of birth, sex, and control number, by reading a barcode (not shown) written on an ID tag such as a wristband worn by the subject (living body) with the barcode reader 235. Note that in the present invention, the subject's information may be input to the control unit 250 by, for example, an input operation on the operation unit 230 (same as above) other than the barcode reader 235. The control unit 250 causes the display unit 220 to display candidates showing multiple corresponding examination mode candidates based on the read radiopharmaceutical information and subject information. The user selects one of the displayed multiple examination mode candidates by operating the keyboard 233 or mouse 232. Then, the control unit 250 operates the plunger driving unit 51 in the operation mode corresponding to the selected examination mode. In the case of this embodiment, the "operation mode" here includes the movement speed of plunger drive unit 51, the movement time of plunger drive unit 51, and the operation start / end timing. Therefore, by appropriately selecting the examination mode, the desired administration speed, administration start / end timing, and required administration time (the time from the start of administration to the end of administration) are automatically set, and the radiopharmaceutical can be administered to the subject with these settings. It should be noted that the present invention is not limited to this example, and for example, the "operation mode" may include the movement amount (drive amount) of plunger drive unit 51. In other words, the amount of contents (radioactive pharmaceutical or physiological saline) to be drawn into syringe 110 or the amount of contents to be discharged from syringe 110 may be configured to be automatically adjusted according to the selection result of the examination mode.

[0049] The operation of the medicine injection device 300 will now be described. First, consumables are attached to the main unit 100. More specifically, the plurality of three-way stopcocks 60, syringes 111, 112, first flow path tube 72, second flow path tube 73, and air vent filter 79 are attached to the front panel 12. In addition, the tip of the administration needle 150 of the first flow path tube 72 (tube with an administration needle) is inserted into the drainage bottle 140. At this time, the main unit 100 may be in a state in which the second mounting portion 17 is mounted on the mounting surface 400, as shown in FIGS. 4 and 5. This makes it easier to attach the consumables to the front panel 12. In particular, when attaching the adapter 120 that holds the syringe 111 to the syringe holding portion 31 as described above, the adapter 120 can be placed in the storage area between the first plate-shaped portion 32a and the second plate-shaped portion 32b with the adapter 120 laid at an angle closer to horizontal. This prevents the adapter 120 from shifting in position relative to the syringe holding portion 31 in the vertical direction, facilitating the insertion of the pair of protrusions 129 into the corresponding insertion grooves 37. In this embodiment, a syringe 111 in which a dose of radiopharmaceutical is stored in advance is attached to the adapter 120. Air is removed from the syringe 111 in advance. During the administration operation, substantially the entire amount of the radiopharmaceutical stored in the syringe 111 is administered to the living body. 8, the drug injection device 300 includes a drainage bottle housing section 270 that houses the drainage bottle 140. The drainage bottle housing section 270 has an administration needle holding section 272, and by holding the administration needle 150 with the administration needle holding section 272, the tip of the administration needle 150 can be kept well inserted into the drainage bottle 140.

[0050] Next, the barcode printed on the container containing the radiopharmaceutical to be administered and the barcode printed on the ID tag worn by the subject (living body) are read by the barcode reader 235. The control unit 250 causes the display unit 220 to display candidates showing multiple corresponding types of examination modes based on the read information on the radiopharmaceutical and the information on the subject. The user selects one of the displayed multiple types of examination mode candidates by inputting an operation on the operation unit 230. More specifically, as shown in FIG. 15, the basic screen (home screen) of the display unit 220, which is normally displayed, displays three options, "Select drug," "Return to origin," and "Select administration mode," as an example. The user first reads the barcode on the ID tag worn by the subject (living body) using the barcode reader 235. Next, the user selects "Select drug" and reads the barcode on the container containing the radiopharmaceutical to be administered using the barcode reader 235. As a result, as shown in FIG. 16(a), the control unit 250 causes the display unit 220 to display candidates for corresponding radiopharmaceuticals, such as "Drug A" and "Drug B," based on the information on the read radiopharmaceutical. The user selects a radiopharmaceutical to be administered from the candidates displayed on the display unit 220. Subsequently, the user returns to the basic screen as necessary and selects "Return to origin." As a result, the control unit 250 drives the plunger drive unit 51 to move the plungers 116 of the syringes 111 and 112 to the top dead center (a state where they are pulled out from the syringe body 115 to the limit). Next, the user returns to the basic screen and selects "Select administration mode." As a result, the control unit 250 causes the display unit 220 to display candidates showing multiple types of examination modes (and therefore operation modes) corresponding to the "first operation mode" and "second operation mode" (for example, corresponding to the type of radiopharmaceutical selected) based on the read information on the radiopharmaceutical and the information on the subject. The user selects the desired examination mode (operation mode) from the displayed candidates.

[0051] Next, the control unit 250 performs the operation of administering the radiopharmaceutical to the living body in the selected operation mode (for example, administration rate, administration start / end timing, and required administration time). At this time, in the case of this embodiment, the main body unit 100 is in a state where the first mounting portion 16 is mounted on the mounting surface 400 as shown in Figures 2 and 3, that is, the syringe 111 is held by the syringe holding portion 31 with the outlet 114 facing obliquely upward. During administration, first, physiological saline is drawn into syringe 112. More specifically, with storage pack 74 and syringe 112 in communication with each other via second three-way stopcock 62 driven by three-way stopcock drive unit 56, plunger 116 of syringe 112 is pulled out in the pulling direction by plunger drive unit 53. This performs a suction operation in which physiological saline in storage pack 74 is drawn into syringe 112 via physiological saline flow path 78 (second flow path tube 73 and second three-way stopcock 62). Next, with syringe 112 and first flow path tube 72 in communication with each other via second three-way stopcock 62 and first three-way stopcock 61 driven by three-way stopcock drive unit 56, plunger 116 of syringe 112 is pushed in the pushing direction by plunger drive unit 53. In this way, a slight excess of the saline solution drawn into the syringe 112 is introduced into the administration flow path 77 (first three-way stopcock 61 to administration needle 150) in an amount equivalent to the total value of the dead spaces (internal volumes) of the first three-way stopcock 61, the air vent filter 79, the first flow path tube 72, and the administration needle 150. The introduced saline solution is discharged into the drainage bottle 140 via the administration needle 150. In the present embodiment, as described above, the syringe holding portion 36 holds the syringe 112 with the outlet 114 facing obliquely upward, which facilitates venting the air from inside the syringe 112 (removal of gas from inside the syringe body 115). Furthermore, by introducing physiological saline into the administration flow path 77, the gas inside the first three-way stopcock 61 and the second three-way stopcock 62 can be removed through the air vent filter 79, and the gas inside the first flow path tube 72 and the administration needle 150 can be exhausted into the drainage bottle 140. On the other hand, since the physiological saline solution is dispensed by moving the plunger 116 of the syringe 112 obliquely upward, the energy required to drive (move) the plunger 116 can be reduced compared to moving it vertically upward.

[0052] Next, the administration needle 150 is inserted into the living body, and with the syringe 111 and the administration flow path 77 connected to each other via the first three-way stopcock 61 by driving the three-way stopcock drive unit 56, the plunger 116 of the syringe 111 is pushed in the pushing direction by the plunger drive unit 52. In this way, an administration operation is performed in which the radiopharmaceutical in the syringe 111 flows into the living body via the first three-way stopcock 61, the air vent filter 79, the first flow path tubing 72, and the administration needle 150 (administration flow path 77). Next, the plunger drive unit 53 administers the remaining saline solution in the syringe 112 to the living body via the second three-way stopcock 62, the first three-way stopcock 61, the air vent filter 79, the first flow path tubing 72, and the administration needle 150. This allows a rinsing operation to be performed in which the radiopharmaceutical remaining in the administration flow path 77 is administered to the living body while being rinsed away with saline. In this way, the administration of the radiopharmaceutical to the living body is completed.

[0053] Here, in the case of this embodiment, as described above, syringe holding part 33 holds syringe 111 with outlet 114 facing obliquely upward, which makes it easy to remove air from inside syringe 111 (removal of gas inside syringe body 115). Therefore, (in addition to the air being removed in advance as described above), removal of gas inside syringe body 115 can be more reliably performed. This makes it easy to administer a radiopharmaceutical or physiological saline solution that is substantially free of air to a living body. On the other hand, since the radiopharmaceutical is dispensed by moving plunger 116 of syringe 111 obliquely upward, the energy required to drive (move) plunger 116 can be reduced compared to moving it vertically upward. As described above, by selecting a position in which the outlet 114 faces diagonally upward, the gas inside the syringe body 115 can be removed effectively without using the air vent filter 79. However, by selecting a position in which the outlet 114 faces diagonally upward and using the air vent filter 79, the air inside the syringe 110 (syringe 111 and syringe 112) can be more reliably removed.

[0054] As described above, in this embodiment, the control unit 250 performs the operation of administering the radiopharmaceutical to the living body in the selected operation mode (administration rate, administration start / end timing, and required administration time). More specifically, the control unit 250 drives each of the plunger driving units 52 and 53 at an operation speed corresponding to the selected operation mode. Thus, the administration of the saline solution and the administration of the radiopharmaceutical can be performed at an administration speed (flow rate) corresponding to the selected operation mode. Note that in the present invention, the administration speed (flow rate) of the saline solution and the administration speed (flow rate) of the radiopharmaceutical may be different from each other or may be the same as each other. Furthermore, the control unit 250 starts an administration operation of flowing the radiopharmaceutical from the syringe 111 into the living body at an administration start timing corresponding to the selected operation mode. Similarly, the control unit 250 completes the administration operation at an administration end timing corresponding to the selected operation mode. This allows the control unit 250 to perform the administration operation within the administration required time corresponding to the selected operation mode or within that time. The present invention is not limited to this example, and the "administration start timing corresponding to the selected operation mode" may be the start timing of the suction operation of aspirating saline into syringe 112, and the "administration end timing corresponding to the selected operation mode" may be the completion timing of the rinsing operation of administering the radiopharmaceutical to a living body while rinsing it with saline remaining in administration flow path 77. In this case, the administration required time corresponding to the selected examination mode is the time required from the suction operation to the rinsing operation.

[0055] <Modification of the second embodiment> Next, a modified example of the second embodiment will be described with reference to FIGS. 17(a) and 17(b). The drug injection device 300 according to this modification differs from the drug injection device 300 according to the first embodiment in the following respects, but is otherwise configured similarly to the drug injection device 300 according to the first embodiment. Note that the two-dot chain lines 410 and 420 shown in Figures 17(a) and 17(b) are imaginary straight lines passing through the axis of the syringe 110.

[0056] In this modified example, the first inclination angle α (Figure 17(a)), which is the inclination angle of the syringe 110 held by the syringe holding portion 31 when the first mounting portion 16 is placed on the mounting surface 400, and the second inclination angle β (Figure 17(b)), which is the inclination angle of the syringe 110 held by the syringe holding portion 31 when the second mounting portion 17 is placed on the mounting surface 400, are set to be equal to each other. With this configuration, even if the orientation of syringe 110 is switched between an orientation in which spout 114 faces obliquely upward and an orientation in which spout 114 faces obliquely downward, the tilt angle of syringe 110 can be kept unchanged.

[0057] Third Embodiment Next, a third embodiment will be described with reference to FIG. The drug administration device 300 of this embodiment differs from the drug administration device 300 of the second embodiment described above in the points described below, but is otherwise configured in the same way as the drug administration device 300 of the second embodiment described above.

[0058] As shown in Figure 18, in this embodiment, the drug administration device 300 includes the above-mentioned main body unit 100 including a syringe holding section 31 and a plunger driving section 51, a second main body unit 500 including a second syringe holding section (not shown) and a second plunger driving section (not shown), and a connecting flow path 530 that interconnects the syringe 110 held in the syringe holding section 31 and the second syringe 510 held in the second syringe holding section. In the present invention, the second syringe holding unit may be configured similarly to the above-described syringe holding unit 31, or may have a different configuration from the syringe holding unit 31. Similarly, the second plunger driving unit may be configured similarly to the above-described plunger driving unit 51, or may have a different configuration from the plunger driving unit 51.

[0059] More specifically, medicine administration device 300 includes, for example, syringe 110 including syringe 113 in addition to syringes 111 and 112 described above, and includes second syringe 512 and second syringe 513 as second syringe 510. Syringe 111 is previously filled with a drug, and syringe 113 is used to administer the drug stored in syringe 111 to a living body. A drug is stored in second syringe 512 in advance, and second syringe 513 is used when administering the drug stored in second syringe 512 to a living body. Drug administration device 300 further includes, as three-way stopcock 60, a third three-way stopcock 63 directly connected to syringe 113, a fourth three-way stopcock 64 directly connected to second syringe 512, and a fifth three-way stopcock 65 directly connected to second syringe 513. In this embodiment, third three-way stopcock 63 interconnects first three-way stopcock 61 and second three-way stopcock 62. Furthermore, fourth three-way stopcock 64 and fifth three-way stopcock 65 are directly connected to each other. In this embodiment, the flow path 76 includes a connecting flow path 530 that connects the first three-way stopcock 61 and the fifth three-way stopcock 65 to each other. The plurality of flow path tubes 71 further includes, for example, a third flow path tube 521 and a fourth flow path tube 522. In this embodiment, the connection flow path 530 is configured by a fourth flow path tube 522. A portion of the administration flow path 77 is configured by a third flow path tube 521, and the syringe 110 and the living body are connected via the first flow path tube 72 and the third flow path tube 521.

[0060] In this embodiment, the drug stored in syringe 111 and the drug stored in second syringe 512 are different types of drugs. More specifically, the drug stored in syringe 111 is, for example, a radiopharmaceutical for a SPECT examination, and the drug stored in second syringe 512 is, for example, a radiopharmaceutical for a stress myocardial scintigraphy examination. With this configuration, two types of drugs can be administered to a living body by the drug administration device 300. In the present invention, the drug may be stored in only one of syringe 111 and second syringe 512. Furthermore, the drug stored in syringe 111 and the drug stored in second syringe 512 may be the same type of drug.

[0061] As shown in Figure 18, the medicine injection device 300 further includes a portable second main body unit 500 that is placed on a horizontal placement surface. In Figure 18, the main body unit 100 and the second main body unit 500 are each schematically illustrated by two-dot chain lines. Similar to the main body unit 100, the second main body unit 500 is provided with, in addition to the second syringe holding section and second plunger driving section described above, a three-way stopcock holding section, a plunger gripping section, a three-way stopcock driving section, and a control section (second main body unit side control section). The second main body unit 500 is equipped with a second syringe 512, a second syringe 513, a fourth three-way stopcock 64, and a fifth three-way stopcock 65. Furthermore, syringes 111 to 113 and first to third three-way stopcocks 61 to 63 are mounted on main body unit 100. Furthermore, the second main body unit side controller is electrically connected to, for example, a main body unit side controller 90 provided in the main body unit 100 via a connection cable 540. This allows the medicine injection device 300 to control the operation of both the syringe 110 mounted on the main body unit 100 and the second syringe 510 mounted on the second main body unit 500. The syringe 110 mounted on the main body unit 100 and the second syringe 510 mounted on the second main body unit 500 are in communication with each other via a connection flow path 530 . Note that Figure 18 shows an example in which the syringe 112 mounted on the main body unit 100 and the second syringe 513 mounted on the second main body unit 500 are interconnected via the connecting flow path 530 (fourth flow path tube 522), but the present invention is not limited to this example, and another syringe 110 mounted on the main body unit 100 and another second syringe 510 mounted on the second main body unit 500 may also be interconnected via the connecting flow path 530.

[0062] In the present invention, second syringe 510 (second syringe 512 and second syringe 513) mounted on second main body unit 500 may also be held with outlet 114 facing diagonally upward, similar to syringe 110 (syringe 111 to syringe 113) mounted on main body unit 100, and may be configured so that the contents of second syringe 510 are dispensed by moving plunger 116 of second syringe 510 diagonally upward, or may not be configured in this way. Furthermore, in the present invention, second main body unit 500, like main body unit 100, also includes a base portion (not shown) having a first mounting portion and a second mounting portion that can each be mounted on mounting surface 400, and when first mounting portion is mounted on mounting surface 400, second syringe holding portion holds second syringe 510 with spout 114 facing obliquely upward, and second plunger driving portion drives plunger 116 of second syringe 510 held by second syringe holding portion obliquely upward. The second syringe holding portion may be configured to move the plunger 116 of the second syringe 510 held by the second syringe holding portion obliquely downward to dispense the contents of the second syringe 510, and when the second mounting portion is placed on the mounting surface 400, the second syringe holding portion may hold the second syringe 510 with the outlet 114 facing diagonally downward, and the second plunger driving portion may be configured to move the plunger 116 of the second syringe 510 held by the second syringe holding portion obliquely downward to dispense the contents of the second syringe 510.

[0063] <Modification 1 of the Third Embodiment> Next, a first modified example of the third embodiment will be described with reference to Fig. 19. In Fig. 19, the main unit 100 and the second main unit 500 are each schematically illustrated by two-dot chain lines. The drug administration device 300 of this modified example differs from the drug administration device 300 of the third embodiment described above in the points described below, but is otherwise configured in the same way as the drug administration device 300 of the third embodiment described above.

[0064] In the above third embodiment, an example was described in which the drug is stored in advance in second syringe 510 (more specifically, second syringe 512) in second main body unit 500, but the present invention is not limited to this example, and the drug may be drawn into second syringe 510 directly from another container or via a flow path. More specifically, in this modified example, as shown in FIG. 19, the second main body unit 500 does not have a second syringe 512, but is instead connected to a vial 550 in which a drug is stored, and the second syringe 513 is used when administering the drug stored in the vial 550 to a living body.

[0065] The interior of the vial bottle 550 is sealed by, for example, a lid, and an extraction needle 561 and an air needle 562 are pierced into the lid. Extraction needle 561 is inserted into vial bottle 550 to extract the medicine from vial bottle 550. Air needle 562 connects the inside and outside of vial bottle 550 with each other. The extraction needle 561 is connected to the fourth three-way stopcock 64 via the fifth flow path tube 523, and the drug in the vial bottle 550 is sucked into the second syringe 513 via the extraction needle 561, the fifth flow path tube 523, the fourth three-way stopcock 64, and the fifth three-way stopcock 65 in this order.

[0066] <Modification 2 of the Third Embodiment> Next, a second modification of the third embodiment will be described with reference to FIG. The drug administration device 300 of this modified example differs from the drug administration device 300 of the third embodiment described above in the points described below, but is otherwise configured in the same way as the drug administration device 300 of the third embodiment described above.

[0067] As shown in FIG. 20, in this modified example, the second main unit 500 has the same configuration as the main unit 100. More specifically, the second main body unit 500, like the main body unit 100, includes the above-mentioned base portion 10, and the base portion 10 includes, for example, a housing 20 and a support portion (not shown) that supports the housing 20 so that it can stand on its own. Second syringe holding portion 570 (second syringe holding portion 571 and second syringe holding portion 572) holds second syringe 510 with outlet 114 facing diagonally upward, and a plunger driving portion (not shown) moves plunger 116 of second syringe 510 held by second syringe holding portion 570 diagonally upward to dispense the contents of second syringe 510. In addition, a detachable adapter 120 can be attached to second syringe holding portion 570. Note that Figure 20 shows an example in which the syringe 112 attached to the main body unit 100 and the second syringe 512 attached to the second main body unit 500 are connected to each other via the connecting flow path 530 (fourth flow path tube 522), but the present invention is not limited to this example, and another syringe 110 attached to the main body unit 100 and another second syringe 510 attached to the second main body unit 500 may be connected to each other via the connecting flow path 530.

[0068] Although the embodiments and modifications have been described above with reference to the drawings, these are merely examples of the present invention, and various configurations other than those described above can also be adopted.

[0069] For example, in the above first to third embodiments and their respective modifications, an example has been described in which a drug is administered transdermally to a living body via administration needle 150. However, the present invention is not limited to this example, and a drug may be administered (supplied) by oral ingestion by a living body. In this case, the contents of syringe 110 (drug or saline) are dispensed into a drinking container (not shown).

[0070] Furthermore, in the above first to third embodiments and each modified example, an example has been described in which the drug is stored in the syringe 110 in advance, but the present invention is not limited to this example, and the drug may be drawn into the syringe 110 directly from another container (not shown) or via a flow path.

[0071] Furthermore, in the above second embodiment, an example has been described in which syringe 111 has shielding cover portion 118, and shielding cover portion 118 covers syringe body 115 of syringe 111. However, the present invention is not limited to this example, and shielding cover portion 118 may be provided around syringe holding portion 31 in base portion 10 (for example, front panel 12). In this case, it is preferable that shielding cover portion 118 covers at least the sides and front of syringe 111.

[0072] Furthermore, in the present invention, the number of syringes 110 and second syringes 510, the number of three-way stopcocks 60, and the number of flow path tubes 71 provided in the drug administration device 300 are not limited to the above examples, and can be set appropriately depending on the use of the drug administration device 300, etc.

[0073] The present embodiment encompasses the following technical ideas. (1) A drug administration device for administering a drug to a living body, a syringe holder that holds the syringe with the injection outlet facing obliquely upward; a plunger driving unit that moves the plunger of the syringe held by the syringe holding unit obliquely upward to dispense the content of the syringe; A drug administration device comprising: (2) A base portion is provided to be placed on a horizontal surface; the syringe holding unit and the plunger driving unit are mounted on the base unit, the base portion has a first placement portion and a second placement portion each of which can be placed on the placement surface; When the first mounting portion is placed on the mounting surface, the syringe holding portion holds the syringe with the outlet facing obliquely upward, and the plunger driving portion moves the plunger of the syringe held by the syringe holding portion obliquely upward to dispense the content of the syringe; When the second mounting portion is placed on the mounting surface, the syringe holding portion holds the syringe with the outlet facing diagonally downward, and the plunger driving portion moves the plunger of the syringe held by the syringe holding portion diagonally downward to dispense the contents of the syringe. (1) A pharmaceutical administration device as described above. (3) A pharmaceutical administration device as described in (2), wherein a first inclination angle, which is the inclination angle of the syringe held by the syringe holding portion when the first mounting portion is placed on the mounting surface, and a second inclination angle, which is the inclination angle of the syringe held by the syringe holding portion when the second mounting portion is placed on the mounting surface, are different from each other. (4) the base portion has a front panel; the syringe holder holds the syringe along the front panel; The syringe can be attached to and detached from the syringe holding portion from the front side of the front panel, The medicine injection device according to (3), wherein the second tilt angle is smaller than the first tilt angle. (5) A detachable adapter can be attached to the syringe holding portion, the syringe is attached to the syringe holder via the adapter, A pharmaceutical administration device as described in any one of (1) to (4), wherein the adapter is capable of being interchangeably attached to the syringe holding portion with multiple types of adapters corresponding to syringes of multiple shapes or sizes. (6) A drug administration device according to any one of (1) to (4), wherein the drug is a radioactive drug. (7) The drug administration device according to (6), wherein the radioactive drug is a radioactive drug for SPECT examination. (8) A portable main body unit including the syringe holding unit and the plunger driving unit and placed on a horizontal placement surface, The pharmaceutical administration device according to (7), wherein the weight of the main body unit is 50 kg or less. (9) a main body unit including the syringe holding portion and the plunger driving portion; a second main body unit including a second syringe holding portion and a second plunger driving portion; a connecting flow path that interconnects the syringe held in the syringe holding portion and the second syringe held in the second syringe holding portion; The drug administration device according to any one of (1) to (8), comprising: (10) a display unit that performs a display operation; an operation unit that accepts operations by a user; a control unit that controls the operation of the medicine injection device, including controlling the display operation of the display unit and the operation of the plunger drive unit, in response to an operation of the operation unit; Equipped with When the control unit receives a predetermined trigger, the control unit causes the display unit to display candidates for a plurality of types of examinations; A pharmaceutical administration device as described in (7), wherein when an examination mode is selected from a candidate display showing multiple types of examination mode candidates displayed on the display unit by operating the operating unit, the control unit operates the plunger drive unit in an operating mode corresponding to the selected examination mode. [Explanation of symbols]

[0074] 10 Base 12 Front Panel 13 Cover 15 Support part 16 First placement section 17 Second loading section 20 Case 21 First surface part 22 Second surface part 23 Front part 24 Rear part 25 Pair of side sections 26 Corner 31, 33, 36 Syringe holder 32a First plate-shaped portion 32b Second plate-shaped portion 32c Third plate-shaped part 37 Insertion groove 371 First insertion groove 372 Second insertion groove 37a Part 1 37b Part 2 41, 42, 43 Plunger gripping part 46 Three-way stopcock holding part 47 1st three-way stopcock holding part 48 2nd three-way stopcock holding part 51, 52, 53 Plunger drive unit 56 Three-way stopcock drive unit 57 First three-way stopcock drive unit 58 Second three-way stopcock drive unit 60 Three-way stopcock 61 No. 1 three-way stopcock 62 2nd three-way stopcock 63 Third three-way stopcock 64 No. 4 three-way stopcock 65 No. 5 three-way stopcock 71 Flow path tube 72 First flow path tube 73 Second flow path tube 74 Containment Pack 75a, 75b Connector part 76 Flow path 77 Administration channel 78 Saline fluid channel 79 Air vent filter 81, 82, 83 Plunger drive motor 86 Three-way stopcock drive motor 87 First three-way stopcock drive motor 88 Second three-way stopcock drive motor 90 Main unit side control section 100 Main unit 110, 111, 112, 113 Syringes 114 Spout 115 Syringe body 115a Flange part 116 Plunger 118 Shielding cover part 120 Adapter 121 First Adapter 122 Second Adapter 125 Main body 126 1st bifurcated holding part 126a Notched portion 127 Second bifurcated holding part 127a Notched portion 128 Third bifurcated holding part 128a Notched portion 129 Pair of protrusions 140 Drainage Bottle 150 administration needle 200 Operation terminal 210 cabinet 220 Display section 221 LCD display panel 230 Operation section 232 Mouse 233 keyboard 235 Barcode Reader 240 Storage section 250 control section 251 CPU 252 ROM 253 RAM 270 Drainage bottle storage section 272 Needle holder 280 desk 300 Drug administration device 400 Loading surface 410, 420 Imaginary line passing through the axis of the syringe 500 Second main unit 510, 512, 513 Second syringe 521 Third flow path tube 522 4th flow path tube 523 5th flow path tube 530 Connecting Channel 540 connection cable 550 vials 561 Extraction needle 562 Air Needle 570, 571, 572 Second syringe holder

Claims

1. A drug administration device for administering a drug to a living body, a syringe holder that holds the syringe with the injection outlet facing obliquely upward; a plunger driving unit that moves the plunger of the syringe held by the syringe holding unit obliquely upward to dispense the content of the syringe; A drug administration device comprising:

2. A base portion is provided to be placed on a horizontal placement surface, the syringe holding unit and the plunger driving unit are mounted on the base unit, the base portion has a first placement portion and a second placement portion each of which can be placed on the placement surface; When the first mounting portion is placed on the mounting surface, the syringe holding portion holds the syringe with the outlet facing obliquely upward, and the plunger driving portion moves the plunger of the syringe held by the syringe holding portion obliquely upward to dispense the content of the syringe; The pharmaceutical administration device of claim 1, wherein when the second mounting portion is placed on the mounting surface, the syringe holding portion holds the syringe with the outlet facing diagonally downward, and the plunger driving portion moves the plunger of the syringe held by the syringe holding portion diagonally downward to dispense the contents of the syringe.

3. The pharmaceutical injection device of claim 2, wherein a first inclination angle, which is the inclination angle of the syringe held by the syringe holding portion when the first mounting portion is placed on the mounting surface, and a second inclination angle, which is the inclination angle of the syringe held by the syringe holding portion when the second mounting portion is placed on the mounting surface, are different from each other.

4. the base portion has a front panel; the syringe holder holds the syringe along the front panel; The syringe can be attached to and detached from the syringe holding portion from the front side of the front panel, The medicine injection device according to claim 3 , wherein the second tilt angle is smaller than the first tilt angle.

5. A detachable adapter can be attached to the syringe holding portion, the syringe is attached to the syringe holder via the adapter, The drug injection device according to claim 1 , wherein a plurality of types of adapters corresponding to syringes of a plurality of different shapes or sizes are interchangeably attached to the syringe holding portion as the adapter.

6. The drug administration device according to claim 1 , wherein the drug is a radioactive drug.

7. The drug administration device according to claim 6, wherein the radiopharmaceutical is a radiopharmaceutical for SPECT examination.

8. a portable main body unit including the syringe holding unit and the plunger driving unit, the main body unit being placed on a horizontal placement surface; 8. The drug administration device according to claim 7, wherein the weight of the main body unit is 50 kg or less.

9. a main body unit including the syringe holding portion and the plunger driving portion; a second main body unit including a second syringe holding portion and a second plunger driving portion; a connecting flow path that interconnects the syringe held in the syringe holding portion and the second syringe held in the second syringe holding portion; The drug administration device according to claim 1 , further comprising:

10. a display unit that performs a display operation; an operation unit that accepts operations by a user; a control unit that controls the operation of the medicine injection device, including controlling the display operation of the display unit and the operation of the plunger drive unit, in response to an operation of the operation unit; Equipped with When the control unit receives a predetermined trigger, the control unit causes the display unit to display candidates for a plurality of types of examinations; A pharmaceutical injection device as described in claim 7, wherein when an inspection mode is selected from a candidate display showing multiple types of inspection mode candidates displayed on the display unit by operating the operating unit, the control unit operates the plunger drive unit in an operating mode corresponding to the selected inspection mode.

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