Dosage supporting system and dosage supporting program

Abstract

To provide a dosage supporting system and a dosage supporting program that facilitate completion of dosage of a pharmaceutical by a compression type pharmaceutical injector according to a predetermined set time.SOLUTION: A dosage supporting system 10 includes an acquisition processing unit 71 and an adjustment processing unit 72. The acquisition processing unit 71 acquires target time. The adjustment processing unit 72 adjusts an amount of infusion so as to make dosage time by a compression-type pharmaceutical injector of a prepared pharmaceutical being a mixture of a pharmaceutical and the infusion close to the target time.SELECTED DRAWING: Figure 3

Description

[Technical Field]

[0001] The present invention relates to a medication assistance system and a medication assistance program that assists in part or all of the administration of medication using a pressurized medication injector. [Background technology]

[0002] As a related art, a pressurized medicine injector (infusion device) that injects medicine (drug) into a patient's body by pressurizing means instead of gravity-based intravenous drip is known (see, for example, Patent Document 1). Furthermore, among such pressurized medicine injectors, there is a medicine injector that has a reservoir container and a pressurizing mechanism integrated together and is equipped with a medicine reservoir function. This pressurized medicine injector (medicine injector) is configured such that an elastic medicine bag is built into an outer container. The medicine bag has a structure similar to that of a rubber balloon, and is constantly under contraction force.

[0003] When using the pressure-type medicine injector, the medicine is first injected into the medicine bag using an injector such as a syringe. An indwelling needle is also attached to the patient in advance. The pressure-type medicine injector is then placed near the patient, and the medicine bag of the pressure-type medicine injector is connected to the indwelling needle using an infusion tube. The medicine inside the pressure-type medicine injector is pressurized and pushed out by the contraction force of the medicine bag, and is injected in small amounts into the patient's body via the infusion tube.

[0004] The pressurized drug injector is highly portable and capable of continuous infusion without the need for a power source or an infusion pole, making it possible to provide continuous infusion of, for example, anticancer drugs to patients at home or as outpatients. When administering the drug to a patient using the pressurized drug injector, the drug is injected into the patient's body in minute amounts, making it possible for the patient to receive the drug over a long period of time, such as 48 hours, while staying at home. [Prior art documents] [Patent documents]

[0005] [Patent Document 1] Japanese Patent Application Laid-Open No. 2014-171758 Summary of the Invention [Problem to be solved by the invention]

[0006] However, while the pressurized medicine injector is designed to administer the medicine over a predetermined set time, the actual administration time may exceed or be insufficient compared to the set time, depending on, for example, the patient's condition (including posture, etc.) and behavior. For example, administration beyond the set time can cause strain or anxiety on the patient, which may ultimately result in a decrease in the patient's adherence and quality of life (QOL). Furthermore, if the patient discontinues administration once the set time has elapsed, the entire amount of the medicine stored in the pressurized medicine injector may not be administered.

[0007] An object of the present invention is to provide a medication assistance system and a medication assistance program that make it easier to complete the administration of medication using a pressurized medication injector within a predetermined set time. [Means for solving the problem]

[0008] According to one aspect of the present invention, there is provided a medication support system including an acquisition processor and an adjustment processor. The acquisition processor acquires a target time. The adjustment processor adjusts the amount of the infusion so that the administration time of a prepared medicine, which is a mixture of a medicine and an infusion, using a pressurized medicine injector approaches the target time.

[0009] According to another aspect of the present invention, a medication support system includes an acquisition processor and a comparison processor. The acquisition processor acquires a target time. The comparison processor compares an actual time required to administer a prepared medication, which is a mixture of a medication and an infusion solution, to a patient using a pressure-type medication injector with the target time.

[0010] A medication support program according to another aspect of the present invention is a program for causing one or more processors to execute the steps of obtaining a target time and adjusting the amount of infusion so that the administration time of a prepared drug, which is a mixture of a drug and an infusion, using a pressurized drug injector approaches the target time. [Effects of the Invention]

[0011] According to the present invention, it is possible to provide a medication support system and a medication support program that make it easier to complete the administration of medication using a pressurized medication injector within a predetermined set time. [Brief explanation of the drawings]

[0012] [Figure 1] FIG. 1 is a block diagram showing an example of a medication support system according to an embodiment of the present invention. [Figure 2] FIG. 2 is a schematic diagram showing an example of a pressurized medicine injector in which the medication support system according to the embodiment of the present invention is used. [Figure 3] FIG. 3 is a schematic block diagram showing the configuration of the control unit of the medication support system according to the embodiment of the present invention. [Figure 4] FIG. 4 is a flowchart illustrating an example of the procedure of the medication support process executed by the medication support system according to the embodiment of the present invention. [Figure 5] FIG. 5 is a table showing an example of performance data used in the medication support system according to the embodiment of the present invention. [Figure 6] FIG. 6 is a diagram showing an example of an injection prescription issued by the medication support system according to the embodiment of the present invention. [Figure 7] FIG. 7 is a diagram showing an example of a mixed injection support screen displayed in the medication support system according to the embodiment of the present invention. DETAILED DESCRIPTION OF THE INVENTION

[0013] Hereinafter, embodiments of the present invention will be described with reference to the accompanying drawings to facilitate understanding of the present invention. Note that the following embodiments are examples of specific embodiments of the present invention and are not intended to limit the technical scope of the present invention. Furthermore, the configurations and processing functions described in the following embodiments can be selected and combined as desired.

[0014] [Medication Support System 10] As shown in FIG. 1, a medication support system 10 according to an embodiment of the present invention includes a medication support device 1, a dispensing device 2, a mixed injection support device 3, and a client terminal 4. The medication support device 1, the dispensing device 2, the mixed injection support device 3, and the client terminal 4 are connected to each other via a communication network NT1 so as to be able to communicate wirelessly or wired. The communication network NT1 includes a local area network (LAN), a wide area network (WAN), the Internet, an intranet, or the like. A host system 5 is also connected to the medication support device 1 via the communication network NT1. The medication support system 10 may include a plurality of at least one of the medication support device 1, the dispensing device 2, the mixed injection support device 3, and the client terminal 4.

[0015] In this embodiment, the medication support system 10 supports part or all of the administration (medication) of medicines by a pressurized medicine injector 6 (see FIG. 2). Users of the medication support system 10 are, for example, pharmacists, doctors, nurses, medical staff, or facility managers at medical institutions such as hospitals, nursing homes for the elderly, or pharmacies. In this embodiment, as an example, the medication support system 10 is used in a hospital, and the users of the medication support system 10 are pharmacists (hospital pharmacists) at the hospital.

[0016] Furthermore, in the field of medicines (pharmaceuticals), "medication" as used in this disclosure refers to administering medicine to a patient according to the patient's disease or condition. In particular, the "medication" supported by the medication support system 10 according to this embodiment refers to the administration of medicine to a patient at home or as an outpatient, for example, using the pressurized medicine injector 6. When administering the medicine to a patient using the pressurized medicine injector 6, the medicine is injected into the patient's body in minute amounts, allowing the patient to receive the medicine over a long period of time, such as 48 hours, while staying at home.

[0017] When administering medication using the pressurized medicine injector 6, a user (operator) such as a doctor or pharmacist prepares the medicine in advance and fills the pressurized medicine injector 6 with the prepared medicine. In the field of medicines (pharmaceuticals), "preparation" in this disclosure refers to mixing multiple medicines or preparing them in the appropriate amount depending on the patient's disease or condition, and includes mixing the medicine with a liquid such as an infusion (including an injection), mixing two medicines together, and mixing two liquids together. The medicine includes liquid medicines (medicinal solutions) and powdered medicines (powdered medicines). If the medicine is a powdered medicine, dissolving the powdered medicine in a liquid (solvent) such as an infusion also constitutes mixing the medicine with the liquid. In this embodiment, unless otherwise specified, the preparation process includes a series of steps of mixing the medicine with the infusion based on preparation data and storing (filling) the mixture of the medicine and the infusion (hereinafter referred to as the "prepared medicine") in the pressurized medicine injector 6.

[0018] Here, for example, when a drug (medicinal liquid) is extracted from a drug container using a syringe and injected into the pressure-type drug injector 6 containing the infusion liquid, the prepared drug (a mixture of the drug and the infusion liquid) is generated within the pressure-type drug injector 6. Even when the prepared drug is generated within the pressure-type drug injector 6, the prepared drug is ultimately contained within the pressure-type drug injector 6. Therefore, the manner in which the prepared drug is contained within the pressure-type drug injector 6 includes not only a manner in which the prepared drug is generated outside the pressure-type drug injector 6 and then contained within the pressure-type drug injector 6, but also a manner in which the prepared drug is generated within the pressure-type drug injector 6 and then contained within the pressure-type drug injector 6. As an example, the preparation work involves the preparation of an injection drug such as an anticancer drug.

[0019] The pressure-type medicine injector 6 is an infusion device that injects medicine (drug) into the patient's body by pressurizing means instead of gravity-based drip infusion, and is called an infusion pump or infuser pump. The pressure-type medicine injector 6 integrates a reservoir and a pressurizing mechanism, and has a medicinal liquid storage function for storing medicine and a pressurizing function for injecting medicine into the patient's body.

[0020] As shown in Figure 2, the pressurized medicine injector 6 comprises an outer container 61, a medicine solution bag 62, and an infusion tube 63. The outer container 61 houses the medicine solution bag 62 inside. The medicine solution bag 62 is elastic and has a hollow bag structure like a rubber balloon. Therefore, when the prepared medicine is contained (filled) in the medicine solution bag 62 and the medicine solution bag 62 is inflated inside the outer container 61, a contraction force always acts on the medicine solution bag 62, generating a force that pressurizes the prepared medicine. The infusion tube 63 is connected to the inside of the medicine solution bag 62, and its tip is connected to the indwelling needle attached to patient H1.

[0021] When using the pressurized medicine injector 6, the prepared medicine is injected into the medicine solution bag 62 in advance using an injector such as a syringe. The patient H1 is also fitted with the indwelling needle in advance. The pressurized medicine injector 6 is then placed near the patient H1, and the medicine solution bag 62 of the pressurized medicine injector 6 is connected to the indwelling needle using the infusion tube 63. The prepared medicine in the pressurized medicine injector 6 is pressurized and pushed out by the contraction force of the medicine solution bag 62, and is injected in small amounts into the body of the patient H1 via the infusion tube 63.

[0022] The pressurized drug injector 6 is highly portable and capable of continuous infusion without the need for a power source or an infusion pole, making it possible to perform continuous infusion of, for example, an anticancer drug to the patient H1 at home or in an outpatient clinic. When administering the drug to the patient H1 using the pressurized drug injector 6, the drug is injected into the body of the patient H1 in minute amounts, so the patient H1 can receive the drug over a long period of time, such as 48 hours, while staying at home.

[0023] Based on the preparation data, the medication support system 10 outputs procedures and instructions for each work step included in the preparation work to the dispensing device 2 or the mixed injection support device 3. This allows the user to perform the preparation work in accordance with the output of the dispensing device 2 and / or the mixed injection support device 3.

[0024] For example, the preparation data includes patient information (patient ID, patient name, height, weight, body surface area, etc.), preparation date, drug information (drug code or drug name, etc.), infusion information (infusion code or infusion name, etc.), dosage, regimen identification information, etc. The regimen identification information is information that can identify regimen information, such as therapy name (regimen name), therapy ID, or regimen ID. The preparation data also includes information regarding the type and size (volume) of the pressurized drug injector 6. Furthermore, the preparation data may include information such as doctor information, preparation content information, preparation procedure information (task content, solvent, solvent amount, extraction amount, etc.), administration date, prescription classification, medical department, and ward.

[0025] Specifically, in the preparation work, the user follows the procedures and instructions based on the preparation data, for example, using a syringe to draw up a liquid medicine (medicinal solution) from a medicine container and fill it into the pressurized medicine injector 6 together with an infusion solution such as physiological saline. As a result, the medicine and the infusion solution are mixed to produce the prepared medicine, and the prepared medicine is contained in the pressurized medicine injector 6. The medicine is administered to a patient using the pressurized medicine injector 6 containing the prepared medicine.

[0026] In the medication support system 10, the medication support device 1 can display various types of information about each patient on the client terminal 4 in response to a user's operation of the client terminal 4. The client terminal 4 controls the display screen based on display data transmitted from the medication support device 1, or controls the display screen by referring to various types of data stored in the medication support device 1. The medication support device 1 can also accept operation input to the client terminal 4 by a user.

[0027] Specifically, in this embodiment, a client-server system is configured by the medication support device 1 and the client terminal 4, and the medication support device 1 executes various processes such as display in response to user operations of the client terminal 4. Therefore, in this embodiment, the "display," "operation," "selection," "input," and the like described below will be described as being performed using the client terminal 4. Note that similar displays and operations may also be performed by the medication support device 1.

[0028] The host system 5 is a medical-related system such as an electronic medical record system or a regimen ordering system. The host system 5 may be a separate system from the medication support system 10, and may communicate with the medication support system 10; it need not necessarily be in a "host" relationship with the medication support system 10. The host system 5 can accept inputs of regimen information and test data related to the test results of various tests performed on patients. The host system 5 inputs the regimen information and the test data to the medication support device 1 in response to user operation. The medication support device 1 may also be configured to actively read the regimen information and the test data from the host system 5. Multiple host systems 5 may be provided, and the multiple host systems 5 may include different types of systems. At least one of the regimen information and the test data may be directly input to the medication support system 10 by user operation of the client terminal 4 or the medication support device 1.

[0029] In this embodiment, the medication support device 1 includes a control unit 11, a storage unit 12, a communication I / F (interface) 13, a display unit 14, an operation unit 15, a drive device 16, and the like, as shown in FIG.

[0030] The control unit 11 mainly comprises a computer having one or more CPUs (Central Processing Units) 111 and one or more RAMs (Random Access Memories) 112. The control unit 11 uses the CPU 111 to execute various processes in accordance with various control programs pre-stored in the storage unit 12, etc.

[0031] The storage unit 12 includes storage areas such as a data area, a program area, and a master area. The storage unit 12 may include a plurality of storage media, and the data area, the program area, and the master area may be distributed across the plurality of storage media.

[0032] The data area accumulates and stores the preparation data acquired from the host system 5. The control unit 11 can also newly register or edit the preparation data in response to a user operation. The data area also stores history data indicating the content of the preparation work performed by the user in accordance with the preparation data, in association with the preparation data.

[0033] The program area stores various control programs executed by the control unit 11. The program area also stores application programs such as an operating system (OS) and browser software.

[0034] The master area stores various master information such as a drug master, a patient master, a ward master, a doctor master, and a pharmacist master. For example, the drug master includes information such as a drug ID, drug name, drug code, medicine bottle code, classification (dosage form: powder, tablet, liquid, topical medicine, etc.), specific gravity, drug type (ordinary medicine, anticancer drug, poison, narcotic, powerful drug, antipsychotic, therapeutic drug, etc.), incompatibility, excipient drug, and precautions. Furthermore, the drug master includes information such as the capacity (predetermined amount) and volume (maximum capacity) of the prepared drug in the pressurized drug injector 6. The drug ID is an identification code such as a YJ code, a JAN code, or an RSS code.

[0035] The various pieces of information stored in the storage unit 12 may be stored in advance in the storage unit 12, may be received from outside the medication support system 10 via a telecommunications line, or may be read from a computer-readable recording medium. In other words, the control program, etc. may be provided in a state recorded on a non-transitory recording medium.

[0036] The communication I / F 13 executes data communication with external devices such as the dispensing device 2, the mixed injection support device 3, and the client terminal 4 via the communication network NT1. The communication I / F 13 also executes data communication with the upper system 5.

[0037] The display unit 14 is a device such as a liquid crystal display or an organic EL display that displays various information in accordance with control instructions from the control unit 11. The operation unit 15 is a device operated by a user to input various information to the medication support device 1. The control unit 11 accepts a user operation on the operation unit 15 and executes processing according to the content of the user operation.

[0038] The drive device 16 is a device that reads the OS, the browser software, or the like from a computer-readable recording medium 161 on which the OS, the browser software, or the like is non-temporarily recorded. The drive device 16 may be integrated into the medication support device 1 or may be externally attached to the medication support device 1 by being removably connected to the medication support device 1. The recording medium 161 may be a CD, DVD, BD, or USB memory, and the drive device 16 may be a CD drive, DVD drive, BD drive, or USB port. In the medication support device 1, the control unit 11 reads the control program or the OS, or the like, from the recording medium 161 using the drive device 16 and installs it in the program storage unit of the storage unit 12. The control program may be pre-stored in the storage unit 12, or the medication support device 1 may receive it from an external device via the communication network NT1.

[0039] The pressurized medicine injector 6 is designed to administer the medicine (the prepared medicine) over a predetermined set time. However, the actual administration time may exceed or be insufficient compared to the set time, depending on, for example, the condition (including posture, etc.) and behavior of the patient H1. If the administration is performed beyond the set time, it may cause a burden or anxiety on the patient H1, which may ultimately result in a decrease in the patient H1's adherence and quality of life. Furthermore, if the patient H1 themselves discontinues administration when the set time has elapsed, it may result in the preparation medicine stored in the pressurized medicine injector 6 not being administered in its entirety.

[0040] In consideration of these circumstances, the medication support system 10 according to this embodiment employs a configuration that makes it easier to complete administration of medicine by the pressurized medicine injector 6 within a predetermined set time. Specifically, as shown in FIG. 3, the medication support system 10 includes an acquisition processing unit 71 and an adjustment processing unit 72. The acquisition processing unit 71 acquires a target time. The adjustment processing unit 72 adjusts the amount of infusion so that the administration time of medicine by the pressurized medicine injector 6 approaches the target time.

[0041] According to the medication support system 10, it becomes easier to complete the administration of the medicine by the pressurized medicine injector 6 within a predetermined set time. Details of the functions of the acquisition processing unit 71 and the adjustment processing unit 72 will be explained in the section titled “Medication support method.”

[0042] [Dispenser 2] The dispensing device 2 dispenses the medicines based on dispensing information (dispensing data) related to the dispensing of the medicines. In the present embodiment, as an example, the dispensing device 2 dispenses the medicines and the infusions directly or indirectly by issuing a form such as an injection prescription Sh1.

[0043] Specifically, the dispensing device 2 includes a dispensing unit 21, a form issuing unit 22, a communication I / F 23, a display unit 24, and an operation unit 25. The dispensing device 2 is placed in a medical institution (a hospital in this embodiment) where the medication support system 10 is used, and is used by the user (a pharmacist in this embodiment). In this embodiment, an example will be described in which the dispensing information is the preparation data based on the contents of a prescription corresponding to one patient.

[0044] The dispensing unit 21 dispenses the medicine and the infusion based on the dispensing information. The dispensing unit 21 dispenses ampoules containing the medicine onto a tray transported by a transport means such as a conveyor. Basically, the dispensing unit 21 dispenses the medicine for each patient, and dispenses the medicines to be used for the same patient onto the same tray.

[0045] The form issuing unit 22 issues (prints) a form (the injection prescription Sh1) for the medicine and the infusion based on the dispensing information. The form issuing unit 22 prints the form for the medicine and the infusion for each patient and ejects the form onto the tray for that patient. In other words, the tray is loaded with the medicine and the infusion and / or the forms for the medicine and the infusion used for the same patient. The user (pharmacist) picks up the medicine stored in a refrigerator according to the injection prescription Sh1 which contains at least information about the medicine.

[0046] The communication I / F23 is a communication interface having a network card or the like that performs wireless or wired data communication between external devices such as the medication support device 1, the co-infusion support device 3, and the client terminal 4 via the communication network NT1 in accordance with a predetermined communication protocol.

[0047] The display unit 24 is a device such as a liquid crystal display or an organic EL display that displays various information in accordance with control instructions from the medication support device 1. For example, the display unit 24 executes various processes in accordance with browser software, and displays various information based on the display data received from the medication support device 1.

[0048] The operation unit 25 is a device operated by a user to input various information to the dispensing device 2. Specifically, the operation unit 25 includes a keyboard and a pointing device (such as a mouse) that accepts input operations on various operation screens displayed on the display unit 24.

[0049] The dispensing device 2 may further include control devices such as a CPU, a ROM, a RAM, and an EEPROM (registered trademark), and a barcode reader. The barcode reader reads, for example, a JAN code, an RSS code, or a QR code (registered trademark) as medicine identification information that can identify the type of medicine.

[0050] [Mixed injection support device 3] The mixed injection support device 3 supports the preparation work (mixed injection work) based on the preparation data. The preparation work is performed, for example, in a work room of a safety cabinet, the front of which is partitioned off by a transparent glass door. A user accesses the work room by inserting their hand through the opening of the glass door, and performs the drug preparation work while visually checking the inside of the work room through the glass door. Furthermore, the work of filling (injecting) the drug (the prepared drug) into the drug solution bag 62 of the pressurized drug injector 6 is also performed in the work room.

[0051] Specifically, the mixed injection support device 3 includes a reading unit 31, an imaging unit 32, a communication I / F 33, a display unit 34, and an operation unit 35. The mixed injection support device 3 is placed in a medical institution (a hospital in this embodiment) where the medication support system 10 is used, and is used by the user (a pharmacist in this embodiment).

[0052] The reading unit 31 is a code reading device capable of reading code information such as a one-dimensional code or a two-dimensional code printed on a recipe slip corresponding to the preparation data. The code information includes identification information for identifying the preparation data.

[0053] The photographing unit 32 is disposed facing the inside of the work chamber so as to be able to photograph, for example, a syringe (syringe barrel) of an injector in the work chamber that is handled by a user.

[0054] The communication I / F 33 is a communication interface having a network card or the like that performs wireless or wired data communication between external devices such as the medication support device 1, the dispensing device 2, and the client terminal 4 via the communication network NT1 in accordance with a predetermined communication protocol.

[0055] The display unit 34 is a device such as a liquid crystal display or an organic EL display that displays various information in accordance with control instructions from the medication support device 1. For example, the display unit 34 executes various processes in accordance with browser software, and displays various information based on the display data received from the medication support device 1.

[0056] The operation unit 35 is a device operated by a user to input various pieces of information to the mixed injection support device 3. Specifically, the operation unit 35 includes a keyboard and a pointing device (such as a mouse) that accepts input operations on various operation screens displayed on the display unit 34.

[0057] The mixed injection support device 3 may further include control devices such as a CPU, a ROM, a RAM, and an EEPROM (registered trademark).

[0058] [Client terminal 4] The client terminal 4 is a personal computer including a communication I / F 41, a display unit 42, an operation unit 43, etc. The client terminal 4 is an operation terminal that is placed in a medical institution (a hospital in this embodiment) where the medication support system 10 is used, and is operated by a user (a pharmacist in this embodiment). The client terminal 4 may be a smartphone, a tablet terminal, a wearable terminal, a portable information processing device such as a laptop computer, or the like.

[0059] The communication I / F 41 is a communication interface having a network card or the like that performs wireless or wired data communication according to a predetermined communication protocol between external devices such as the medication support device 1, the dispensing device 2, and the co-infusion support device 3 via the communication network NT1.

[0060] The display unit 42 is a device such as a liquid crystal display or an organic EL display that displays various information in accordance with control instructions. For example, the display unit 42 executes various processes in accordance with browser software, and displays various information based on the display data received from the medication support device 1.

[0061] The operation unit 43 is a device operated by a user to input various information into the client terminal 4. Specifically, the operation unit 43 includes a keyboard and a pointing device (such as a mouse) that accepts input operations on various operation screens displayed on the display unit 42.

[0062] The client terminal 4 further includes a control unit, a storage unit, etc. The control unit executes various processes in accordance with the browser software, thereby accepting user operations on the operation unit 25 and inputting the contents of the user operations to the medication support device 1.

[0063] [Control unit 11] In the medication support system 10 according to this embodiment, the control unit 11 includes the acquisition processing unit 71, the adjustment processing unit 72, the comparison processing unit 73, and the presentation processing unit 74, as shown in FIG. 3 . Specifically, the control unit 11 executes various processes related to medication support processing in accordance with a medication support program, thereby functioning as various processing units, such as the acquisition processing unit 71, the adjustment processing unit 72, the comparison processing unit 73, and the presentation processing unit 74. That is, in this embodiment, the control unit 11 embodies the main functions of the medication support system 10. In other words, the medication support system 10 according to this embodiment only needs to include the control unit 11; it does not necessarily need to include the memory unit 12, the communication I / F 13, the display unit 14, the operation unit 15, the dispensing device 2, the co-infusion support device 3, the client terminal 4, and the like. The control unit 11 may include multiple processors, any one of which may function as the various processing units. Furthermore, some or all of the various processing units may be configured using electronic circuits.

[0064] In another embodiment, some or all of the functions of the control unit 11 may be provided in the dispensing device 2, the co-infusion support device 3, the client terminal 4, the upper system 5, or the like. For example, some or all of the medication support program may be installed in the dispensing device 2, and the control unit of the dispensing device 2 may acquire necessary information from the control unit 11 as needed to execute various processes related to the medication support process. In this case, the dispensing device embodies the main functions of the medication support system 10. Furthermore, in the medication support system 10, the control unit 11 and the dispensing device 2 may cooperate to execute various processes related to the medication support process.

[0065] The acquisition processing unit 71 acquires the target time. In the present disclosure, the "target time" refers to a target time for administering the drug using the pressurized drug injector 6. For example, if the continuous infusion of the drug using the pressurized drug injector 6 is to take "48 hours," the target time is "48 hours," and if the continuous infusion of the drug using the pressurized drug injector 6 is to take "72 hours," the target time is "72 hours."

[0066] In this embodiment, the acquisition processing unit 71 acquires the target time set in accordance with a user operation. Specifically, the user can input an arbitrary time as the target time by operating the operation unit 15, for example, and the acquisition processing unit 71 acquires the time arbitrarily input by the user as the target time. This allows the target time to be freely set.

[0067] The adjustment processing unit 72 adjusts the amount of the infusion so that the administration time of the prepared medicine (a mixture of the medicine and the infusion) by the pressurized medicine injector 6 approaches the target time. In short, the pressurized medicine injector 6 is a mechanism for administering the medicine over a predetermined set time, and the actual administration time may be longer or shorter than the set time depending on, for example, the condition (including posture, etc.) and behavior of the patient H1.

[0068] Here, if the amount of the infusion solution increases, the amount of the prepared medicine (a mixture of the medicine and the infusion solution) also increases, and the time required to administer the prepared medicine (the actual administration time) becomes longer. Conversely, if the amount of the infusion solution decreases, the amount of the prepared medicine (a mixture of the medicine and the infusion solution) also decreases, and the time required to administer the prepared medicine (the actual administration time) becomes shorter. Taking advantage of this, the adjustment processing unit 72 adjusts the amount of the infusion solution to adjust the length of the actual administration time so that the administration time approaches the target time.

[0069] That is, for example, if the administration time exceeds the target time, the adjustment processing unit 72 reduces the amount of infusion to shorten the administration time and bring it closer to (ideally match) the target time. On the other hand, if the administration time is insufficient for the target time, the adjustment processing unit 72 increases the amount of infusion to lengthen the administration time and bring it closer to (ideally match) the target time.

[0070] The comparison processor 73 compares the actual time required to administer the prepared medicine to patient H1 using the pressurized medicine injector 6 with the target time. That is, the actual time required to administer the prepared medicine to patient H1 using the pressurized medicine injector 6 is defined as the actual time, and the comparison processor 73 compares this actual time with the target time. Specifically, the comparison processor 73 determines, for example, whether the actual time exceeds the target time, is short of the target time, or matches the target time as the comparison result. Furthermore, if the actual time exceeds (or falls short of) the target time, the comparison processor 73 calculates the amount (hours or minutes) of excess (or shortage) as the excess / shortage time. If the actual time matches the target time, the excess / shortage time is set to "0."

[0071] The comparison result of the comparison processing unit 73 (including the overage / shortage time) is used to adjust the amount of the infusion in the adjustment processing unit 72. As an example, if the comparison result of the comparison processing unit 73 indicates that the actual time exceeds the target time by "1 hour," the adjustment processing unit 72 reduces the amount of the infusion by the overage / shortage time (1 hour) to shorten the administration time and bring it closer to (ideally match) the target time. Also, if the comparison result of the comparison processing unit 73 indicates that the actual time is "0.5 hour" short of the target time, the adjustment processing unit 72 increases the amount of the infusion by the overage / shortage time (0.5 hour) to lengthen the administration time and bring it closer to (ideally match) the target time.

[0072] In this way, the adjustment processing unit 72 adjusts the amount of infusion based on actual results of administering the drug to patient H1 using the pressurized drug injector 6. The actual time is an example of the actual value. As a result, the amount of infusion is adjusted based on the results (actual values) of administering the prepared drug to patient H1 using the pressurized drug injector 6, making it possible to bring the administration time closer to the target time in a relatively simple yet accurate manner.

[0073] In particular, in this embodiment, as described above, the actual value includes the actual time required to administer the prepared medicine to patient H1 using the pressurized medicine injector 6. The adjustment processing unit 72 adjusts the amount of infusion based on the comparison result between the actual time and the target time (the comparison result of the comparison processing unit 73). That is, if the administration time actually required to administer the prepared medicine to patient H1 using the pressurized medicine injector 6 exceeds the target time, the adjustment processing unit 72 reduces the amount of infusion, and if the administration time is short of the target time, the adjustment processing unit 72 increases the amount of infusion, thereby enabling the administration time to approach the target time in a relatively simple yet accurate manner.

[0074] The presentation processor 74 presents output information related to the adjusted amount of infusion. That is, the output information related to the amount of infusion adjusted by the adjustment processor 72 is presented to the user by the presentation processor 74. The "presentation" here can include various aspects, such as display on the display unit 14, printing (printing) output by the document issuing unit 22, display on the dispensing device 2 (the display unit 24), display on the mixed injection support device 3 (the display unit 34), or audio output. In the present embodiment, as an example, the presentation processor 74 presents the amount of infusion adjusted by the adjustment processor 72 in a user-recognizable form by printing (printing) output by the document issuing unit 22 and displaying on the mixed injection support device 3 (the display unit 34). This allows the user to easily understand the amount of infusion to be used when performing the preparation work.

[0075] [Medication support processing] Hereinafter, the medication support process executed mainly by the control unit 11 in the medication support system 10 will be described with reference to FIGS.

[0076] <Step S1> In the medication support process, first, in step S1, the acquisition processing unit 71 of the control unit 11 acquires the regimen information. The regimen information includes the dosage of the drug (an anticancer drug in this embodiment), the upper limit amount of the infusion (physiological saline in this embodiment), and the time required for administering the drug (the target time). In step S1, the acquisition processing unit 71 acquires at least the target time by acquiring the regimen information.

[0077] In this embodiment, the acquisition processing unit 71 acquires the target time set in accordance with a user operation. Specifically, the control unit 11 can newly register or edit the preparation data in accordance with a user operation. Therefore, when the preparation data is edited in accordance with a user operation, the acquisition processing unit 71 acquires the target time in the regimen information included in the preparation data, thereby acquiring the target time set in accordance with a user operation.

[0078] <Step S2> In step S2, the comparison processing unit 73 of the control unit 11 reads out performance data relating to past administrations of the prepared medicine to patient H1 using the pressurized medicine injector 6. The performance data read out at this time is limited to data relating to the same total amount of the medicine and the infusion. The performance data includes the amount of the medicine administered, the amount of the infusion, and the actual administration time (the performance time) for one or more past administrations of the prepared medicine. In this embodiment, the performance data read out in step S2 is limited to the performance data for the current patient H1.

[0079] The performance data is registered, for example, by manual input by the patient H1 or a user, and stored (memorized) in the storage unit 12. Alternatively, at least a portion of the performance data (such as the performance time) may be measured by a measurement means and automatically stored in the storage unit 12. The comparison processing unit 73 reads out the performance data from the storage unit 12. Here, when the performance data for the patient H1 is stored multiple times in the storage unit 12, the storage unit 12 reads out the performance data from the most recent to a predetermined number of times from the multiple times of the performance data.

[0080] <Step S3> In step S3, the comparison processing unit 73 calculates a representative value of the performance times. In the present disclosure, the "representative value" refers to, for example, an average value, a median value, a mode value, a maximum value, or a minimum value. In the present embodiment, as an example, the comparison processing unit 73 calculates an average value of the performance times as the representative value of the performance times.

[0081] Here, since the performance data read in step S2 includes the performance times for up to the predetermined number of times, the comparison processing unit 73 calculates the average value of the performance times for up to the predetermined number of times. If the performance data includes the performance time for only one time, the comparison processing unit 73 sets the performance time as the average value of the performance times.

[0082] In this manner, in this embodiment, the representative value of the actual time (an example of the actual value) is calculated, and the adjustment processing unit 72 adjusts the amount of infusion based on the representative value. In other words, the actual value used to adjust the amount of infusion is a representative value of the actual results of multiple administrations of the prepared medicine using the pressure-type medicine injector. Therefore, even if the actual value contains outliers or other variations, the amount of infusion can be accurately adjusted without being affected by the variations.

[0083] <Step S4> In step S4, the comparison processing unit 73 calculates the ratio of the actual time (the representative value of the actual time) to the target time by comparing the target time with the representative value of the actual time (the average value in this embodiment). The "ratio" here is, for example, a value obtained by dividing the actual time (the representative value of the actual time) by the target time, expressed as a percentage. In other words, if the actual time (the representative value of the actual time) matches the target time, the ratio is 100%; if the actual time (the representative value of the actual time) exceeds the target time, the ratio exceeds 100%; and if the actual time (the representative value of the actual time) is short of the target time, the ratio is less than 100%.

[0084] <Step S5> In step S5, the adjustment processing unit 72 calculates a conversion value using the comparison result (the ratio) of the comparison processing unit 73. The "conversion value" here refers to a value obtained by converting the total amount of the drug and the infusion administered over the actual time in the performance data into an amount that will be administered when the target time has elapsed. Specifically, the adjustment processing unit 72 calculates the conversion value by dividing the total amount of the drug and the infusion administered over the actual time in the performance data by the ratio.

[0085] <Step S6> In step S6, the adjustment processing unit 72 calculates the adjusted amount of infusion using the conversion value. Specifically, the adjustment processing unit 72 calculates the adjusted amount of infusion by subtracting the administered amount of the drug included in the regimen information from the conversion value. In other words, the total amount of the drug and the infusion that will be completed when the target time has elapsed if the prepared drug is administered at the same pace as the actual data is calculated as the conversion value. By subtracting the administered amount of the drug from the conversion amount, the amount of infusion that will be completed when the target time has elapsed is calculated.

[0086] In this way, based on the comparison result between the actual time and the target time, the adjustment processing unit 72 calculates the total amount (the converted value) of the medicine and the infusion to be administered to patient H1 using the pressurized medicine injector 6 at the target time, and adjusts the amount of the infusion based on this total amount. In this way, the amount of the infusion can be adjusted so that administration is completed at the target time.

[0087] <Step S7> In step S7, the adjustment processing unit 72 determines whether the amount of infusion (calculated amount) calculated in step S6 is equal to or less than the upper limit amount of infusion included in the regimen information. If the calculated amount is equal to or less than the upper limit amount (S7: Yes), the control unit 11 shifts the process to step S8. If the calculated amount exceeds the upper limit amount (S7: No), the control unit 11 shifts the process to step S9.

[0088] <Step S8> In step S8, the presentation processing unit 74 of the control unit 11 presents the amount of infusion calculated in step S6 (the calculated amount) to the user as the amount of infusion to be filled into the pressurized drug injector 6 by printing (printing) output by the report issuing unit 22 and displaying on the mixed injection support device 3 (the display unit 34).

[0089] <Step S9> In step S9, the presentation processing unit 74 of the control unit 11 presents to the user the upper limit amount of the infusion contained in the regimen information, rather than the amount of the infusion calculated in step S6 (the calculated amount), as the amount of the infusion to be filled into the pressurized drug injector 6, by printing (printing) output by the report issuing unit 22 and displaying on the mixed injection support device 3 (the display unit 34).

[0090] In this manner, in this embodiment, the adjustment processing unit 72 adjusts the amount of the infusion within a range equal to or less than the upper limit amount specified for the infusion (S6 to S9). Therefore, it is possible to avoid issuing an instruction to fill the pressurized medicine injector 6 with an amount of the infusion exceeding the upper limit amount specified in the regimen information, etc.

[0091] In this embodiment, the adjustment processing unit 72 adjusts the amount of infusion for each patient H1. That is, since the variation in the actual time is often due to, for example, the state (including posture, etc.) and behavior of the patient H1, by adjusting the amount of infusion for each patient H1, it is possible to accurately adjust the amount of infusion.

[0092] It should be noted that the above flowchart is merely an example, and processes may be added or omitted as appropriate, and the order of processes may be changed as appropriate.

[0093] Specific examples of application of the medication support process will be described below with reference to Figures 5 to 7. Figure 5 shows the past performance data for the most recent five injections of a certain patient H1. Figure 6 shows an example of the injection prescription Sh1, and Figure 7 shows an example of the mixed injection support screen G1 displayed on the display unit 34 of the mixed injection support device 3.

[0094] Here, we will assume that the drug is administered to patient H1 using the pressurized drug injector 6, which has a capacity of 100 mL and an administration time of 48 hours. That is, we will assume that the total volume of the drug and the infusion is 100 mL, and that the drug is administered to patient H1 over 48 hours using the pressurized drug injector 6. In other words, the target time is "48 hours." We will assume that the drug is "fluorouracil injection (5-FU)" with a concentration of "50 mg / mL," and the infusion is physiological saline.

[0095] In the example of Figure 5, the actual times are "49 hours" for the first infusion, "51 hours" for the second infusion, "53 hours" for the third infusion, "55 hours" for the fourth infusion, and "52 hours" for the fifth infusion, so the average is "52 hours." In this case, the ratio (actual time / target time) when comparing the actual time with the target time is "108%." Therefore, the total amount (converted value) of the drug and the infusion administered to patient H1 using pressurized drug injector 6 in the target time (48 hours) is "92.3 mL."

[0096] Here, if the current regimen information for the sixth infusion specifies the drug dosage as "3000 mg," converting the drug into a liquid volume equals "60 mL." Therefore, by subtracting the liquid volume of the drug (60 mL) from the conversion value (92.3 mL), the infusion volume becomes "32.3 mL" (= 92.3 mL - 60 mL).

[0097] 6, the amount of the medicine (5-FU) prepared is "60.0 mL" and the amount of the infusion (ABC saline) prepared is "32.3 mL." In other words, the amount of the infusion before adjustment is "40.0 mL" (=100 mL-60 mL), but the medication support system 10 adjusts the amount of the infusion, changing the amount of the infusion to "32.3 mL."

[0098] 7, the amount of the drug (5-FU) extracted is set to "60.0 mL" and the amount of the infusion (ABC saline) extracted is set to "32.3 mL." That is, while the amount of the infusion before adjustment is "40.0 mL" (=100 mL-60 mL), the medication support system 10 adjusts the amount of the infusion, changing the amount of the infusion to "32.3 mL."

[0099] Incidentally, when the medicine is a powder, the value in the "Liquid Volume Conversion" column in FIG. 5 is the amount of the medicine dissolved in the infusion solution, and is equal to the amount of the infusion solution used to dissolve the medicine. In other words, the value in the "Liquid Volume Conversion" column in FIG. 5 indicates a fixed amount of the infusion solution determined based on the "drug dosage," and the amount of the infusion solution cannot be adjusted by the adjustment processing unit 72. In this case, the adjustment processing unit 72 can actually adjust only the portion corresponding to the value in the "Infusion Solution" column in FIG. 5. However, even in this case, the sum of the value in the "Liquid Volume Conversion" column and the value in the "Infusion Solution" column is the total amount of the infusion solution. Therefore, adjusting only the portion corresponding to the value in the "Infusion Solution" column by the adjustment processing unit 72 is equivalent to adjusting the total amount of the infusion solution. Similarly, when the medicine consisting of a liquid chemical is diluted to a predetermined concentration with the infusion, the amount of the diluted medicine (i.e., medicine + infusion) is determined in "liquid volume conversion," and therefore the amount of the infusion used for dilution is not subject to adjustment by the adjustment processing unit 72.

[0100] [Other features] The medication support system 10 may simply compare the actual time with the target time without adjusting the amount of infusion. That is, if the result of comparing the actual time (the representative value of the actual time) with the target time shows that the actual time exceeds the target time, the user may decide to reduce the amount of infusion. Conversely, if the actual time is found to be insufficient compared to the target time, the user may decide to increase the amount of infusion.

[0101] As described above, the medication support system 10 according to this embodiment is only required to include the acquisition processing unit 71 and the comparison processing unit 73. The acquisition processing unit 71 acquires a target time. The comparison processing unit 73 compares the actual time required to administer the prepared medicine to patient H1 using the pressurized medicine injector 6 with the target time. In other words, the medication support system 10 may simply issue a warning when the actual time exceeds or falls short of the target time. Alternatively, when the comparison processing unit 73 calculates the excess / deficiency time, the excess / deficiency time is presented to the user, allowing the user to determine how much the infusion volume should be increased or decreased.

[0102] Furthermore, the comparison result between the actual time and the target time can be used to analyze the tendency of patients whose administration time is likely to exceed (or be short of) the target time. For example, the comparison result can be used as statistical data, such as the tendency of patients with certain weight, height, age, sex, blood pressure, or lifestyle habits to have the administration time exceed the target time.

[0103] The conversion value that allows administration within the target time for each patient may also be stored in the storage unit 12. In this case, the conversion value for each patient is updated as needed based on the actual value (the actual time), making it possible to use the conversion value that is appropriate for that patient.

[0104] Furthermore, when administering medication to a certain patient using the pressurized medicine injector 6, the medication support system 10 may adjust the amount of infusion using the performance data of another patient. In this case, it is preferable to classify patients according to their attributes, such as weight, height, age, sex, blood pressure, or lifestyle habits, and refer to the performance data of patients in the same classification.

[0105] Furthermore, an upper and / or lower limit for the amount of the infusion may be determined based on the concentration of the drug in the mixture of the drug and the infusion solution (the prepared drug). For example, if the amount of the infusion solution exceeds the upper limit, the concentration of the drug in the prepared drug will be below a specified range, and the amount of the infusion solution is adjusted to be equal to or less than the upper limit. Similarly, if the amount of the infusion solution falls below the lower limit, the concentration of the drug in the prepared drug will be above the specified range, and the amount of the infusion solution is adjusted to be equal to or greater than the lower limit.

[0106] Furthermore, when there is a change in the amount of infusion, the presentation processing unit 74 may output a notice to that effect to the host system 5 or the like, and provide feedback to, for example, a doctor or the like.

[0107] [Variations] The multiple components included in the medication support system 10 may be distributed across multiple housings. Conversely, the multiple components distributed across multiple housings in the above embodiment may be integrated into one housing.

[0108] [Appendix to the invention] The following is a summary of the invention extracted from the above-described embodiment. Note that the configurations and processing functions described in the following supplementary notes can be selected and combined as desired.

[0109] <Appendix 1> an acquisition processing unit that acquires a target time; and an adjustment processing unit that adjusts the amount of the infusion so that the administration time of the prepared drug, which is a mixture of the drug and the infusion, by the pressure-type drug injector approaches the target time. Medication support system.

[0110] <Appendix 2> the adjustment processing unit adjusts the amount of the infusion based on a performance value related to the administration of the prepared medicine to the patient using the pressurized medicine injector. 10. A medication assistance system as described in Appendix 1.

[0111] <Appendix 3> the performance value includes a performance time required to administer the prepared medication to a patient using the pressurized medication injector; the adjustment processing unit adjusts the amount of the infusion based on a comparison result between the actual time and the target time. 2. A medication assistance system as described in Appendix 2.

[0112] <Appendix 4> the adjustment processing unit calculates a total amount of the medicine and the infusion to be administered to the patient using the pressurized medicine injector at the target time based on a comparison result between the actual time and the target time, and adjusts the amount of the infusion based on the total amount. 4. A medication assistance system as described in Appendix 3.

[0113] <Appendix 5> the performance value is representative of performance over multiple administrations of the prepared drug using the pressurized drug injector; A medication support system according to any one of appendices 2 to 4.

[0114] <Appendix 6> The adjustment processing unit adjusts the amount of the infusion within a range equal to or less than an upper limit amount specified for the infusion. A medication support system according to any one of appendices 1 to 5.

[0115] <Appendix 7> The adjustment processing unit adjusts the amount of the infusion for each patient. A medication support system according to any one of appendices 1 to 6.

[0116] <Appendix 8> a display processing unit configured to display output information related to the adjusted amount of the infusion; A medication support system according to any one of appendices 1 to 7.

[0117] <Appendix 9> the acquisition processing unit acquires the target time set in accordance with a user operation. A medication support system according to any one of appendices 1 to 8.

Claims

1. an acquisition processing unit that acquires a target time; and an adjustment processing unit that adjusts the amount of the infusion so that the administration time of the prepared drug, which is a mixture of the drug and the infusion, by the pressure-type drug injector approaches the target time. Medication support system.

2. the adjustment processing unit adjusts the amount of the infusion based on a performance value related to the administration of the prepared medicine to the patient using the pressurized medicine injector. The medication support system according to claim 1 .

3. the performance value includes a performance time required to administer the prepared medication to a patient using the pressurized medication injector; the adjustment processing unit adjusts the amount of the infusion based on a comparison result between the actual time and the target time. The medication support system according to claim 2 .

4. the adjustment processing unit calculates a total amount of the medicine and the infusion to be administered to the patient using the pressurized medicine injector at the target time based on a comparison result between the actual time and the target time, and adjusts the amount of the infusion based on the total amount. The medication support system according to claim 3 .

5. the performance value is representative of performance over multiple administrations of the prepared drug using the pressurized drug injector; The medication support system according to any one of claims 2 to 4.

6. The adjustment processing unit adjusts the amount of the infusion within a range equal to or less than an upper limit amount specified for the infusion. The medication support system according to any one of claims 1 to 4.

7. The adjustment processing unit adjusts the amount of the infusion for each patient. The medication support system according to any one of claims 1 to 4.

8. a display processing unit configured to display output information related to the adjusted amount of the infusion; The medication support system according to any one of claims 1 to 4.

9. the acquisition processing unit acquires the target time set in accordance with a user operation. The medication support system according to any one of claims 1 to 4.

10. an acquisition processing unit that acquires a target time; a comparison processing unit that compares an actual time required to administer a prepared drug, which is a mixture of a drug and an infusion solution, to a patient using a pressure-type drug injector with the target time; Medication support system.

11. obtaining a target time; adjusting the amount of the infusion solution so that the time of administration of the prepared drug, which is a mixture of the drug and the infusion solution, by the pressurized drug injector approaches the target time; A medication support program for causing one or more processors to execute the above.

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