External skin preparation composition

Abstract

To provide novel external skin preparation compositions containing ingredients that prevent pigmentation caused by melanin production, since UV rays can cause various types of damage to the skin, leading to inflammation, wrinkles, and sagging, as well as pigmentation caused by excessive melanin production, resulting in dark spots and freckles that affect the skin's appearance, and protecting the skin from UV rays by applying sunscreen and inhibiting the melanin production pathway induced by UV rays are effective to prevent pigmentation caused by melanin production.SOLUTION: The present invention provides a novel external skin preparation composition that inhibits melanin production and prevents pigmentation by incorporating hexylresorcinol.SELECTED DRAWING: Figure 1

Description

[Technical Field]

[0001] The present invention relates to a topical skin composition containing hexylresorcinol. Here, the topical skin composition refers to skin care cosmetics such as face washes, lotions, creams, and packs, makeup cosmetics such as foundations, lipsticks, and mascaras, body care cosmetics such as body soaps, slimming agents, UV protection agents, bath additives, and antiperspirants, and fragrance cosmetics such as perfumes and colognes, and also includes legal cosmetics, quasi-drugs, and pharmaceuticals. [Background technology]

[0002] UV rays can cause various types of damage to the skin, leading to inflammation, wrinkles, and sagging. Excessive melanin production can also cause pigmentation, resulting in dark spots and freckles, which can affect the skin's appearance.

[0003] To prevent pigmentation caused by melanin production, it is useful to protect the skin from ultraviolet rays by applying sunscreen and to inhibit the pathway of melanin production induced by ultraviolet rays.

[0004] Hydroquinone, for example, is known as a component that inhibits melanin production, but hydroquinone is unstable and is easily oxidized, and Patent Document 1 discloses a method for stabilizing hydroquinone as a complex. [Prior art documents] [Patent documents]

[0005] [Patent Document 1] Japanese Patent Application Laid-Open No. 2004-99542 DISCLOSURE OF THE INVENTION [Problem to be solved by the invention]

[0006] Against this background, research has progressed into ingredients that prevent pigmentation caused by melanin production, and topical skin preparations have been developed, but the effects of these preparations have not always been satisfactory. [Means for solving the problem]

[0007] The present invention was made under the above circumstances, and provides a novel skin topical composition that inhibits melanin production and prevents pigmentation by incorporating hexylresorcinol.

[0008] The first aspect of the present invention is a skin external preparation composition containing hexylresorcinol.

[0009] Claim 2 of the present invention is the composition for external use on skin according to claim 1, in which hexylresorcinol is contained in an amount of 0.01 to 5.0% by mass. [Effects of the Invention]

[0010] The hexylresorcinol of the present invention inhibits melanin production and prevents pigmentation, and therefore exhibits a skin-lightening effect when incorporated into an external preparation composition. [Brief explanation of the drawings]

[0011] [Figure 1] Figure 1 shows the tyrosinase activity inhibitory effect of the hexylresorcinol of the present invention. When commercial hexylresorcinol is added, it is found to inhibit the activity of tyrosinase, which is involved in the production of dopa from tyrosine, a part of the melanin production pathway, more effectively than other active ingredients, including hydroquinone. DETAILED DESCRIPTION OF THE INVENTION

[0012] The present invention will be described in detail below. The method for producing hexylresorcinol used in the present invention is not particularly limited, but a synthetically obtained product is available as a commercial raw material "SYNOVEA (registered trademark) HR" from Sytheon Ltd. in the United States.

[0013] The amount of hexylresorcinol used in the present invention is 0.01 to 5.0% by mass, preferably 0.1 to 1.0% by mass, based on the total amount of the topical skin composition using the commercially available raw materials. When preparing a typical topical skin composition, if the amount is less than 0.01% by mass, the pigmentation inhibitory effect due to the inhibition of melanin production is not exerted. Although it is conceivable to incorporate hexylresorcinol in an amount exceeding 1.0% by mass up to 5.0% by mass, this is not preferred because the effect commensurate with the amount incorporated gradually saturates.

[0014] The effect of the topical skin preparation composition of the present invention is to inhibit melanin production, thereby suppressing the occurrence of age spots and freckles and leading to brighter skin. Therefore, further effects can be expected by adding a component with a whitening effect to the topical skin preparation composition of the present invention. Such components include vitamin C and its derivatives, arbutin, tranexamic acid, plant extracts, etc.

[0015] In addition to the essential ingredients described above, the topical skin preparation composition of the present invention may contain other ingredients that are typically used in topical skin preparation compositions such as cosmetics and pharmaceuticals. Examples of such other ingredients include the following. The topical skin preparation composition of the present invention is produced by blending one or more of these ingredients with the essential ingredients described above according to a conventional method.

[0016] The oily components include the following: Avocado oil, apricot kernel oil, olive oil, cocoa butter, beef tallow, sesame oil, wheat germ oil, camellia oil, safflower oil, hydrogenated moringa oil, soybean oil, tea seed oil, evening primrose oil, camellia oil, glycolipids, triglyceride (C10-18) glyceryl triphosphate, peppermint leaf oil, palm kernel oil, palm oil, castor oil, sunflower seed oil, boswellia serrata oil, macadamia seed oil, manuka oil, horse fat, melia azadirachta seed oil, cottonseed oil, Japan wax, (moringa oil / hydrogenated moringa oil) esters, coconut oil, lemon fruit oil, phospholipids, horseradish perilla seed oil, etc. Waxes such as carnauba wax, candelilla wax, rice bran wax, hydrogenated jojoba oil, sunflower seed wax, acacia dealbata flower wax, partially hydrogenated jojoba oil, jojoba ester, jojoba seed oil, beeswax, and lanolin. Hydrocarbons such as isoparaffin, hydrogenated polyisobutene, squalane, squalene, ceresin, paraffin, microcrystalline wax, liquid paraffin, and petrolatum. Higher fatty acids such as isostearic acid, oleic acid, stearic acid, palmitic acid, hydroxystearic acid, behenic acid, myristic acid, lauric acid, linoleic acid, and linolenic acid. Higher alcohols such as isostearyl alcohol, 2-octyldodecanol, oleyl alcohol, cholesterol, stearyl alcohol, cetyl alcohol, cetearyl alcohol, soybean sterol, phytosterols, behenyl alcohol, jojoba alcohol, myristyl alcohol, and lanolin alcohol. Alkyl glyceryl ethers such as chimyl alcohol and batyl alcohol. Isostearyl Isostearate, Phytostearyl Isostearate, Propylene Glycol Isostearate, Cetyl 2-Ethylhexanoate, Ethoxydiglycol Behenate, Ethoxydiglycol Oleate, Hydrolyzed Jojoba Esters, Triethyl Citrate, Diethylene Glycol Monoethyl Ether, Glycol Distearate, Propylene Glycol Dinonanoate, Cholesteryl Stearate, Stearyl Stearate, Caprylic / Capric Triglyceride, Triheptanoin, Tri-2- Esters such as glyceryl hexanoate, ethylhexyl palmitate, (behenic acid / oleic acid) (behenyl / oleyl) esters, pentaerythritol tetraester, jojoba fatty acid isopropyl, (jojoba oil / macadamia seed oil) esters, macadamiate ethyl, macadamiate phytosteryl, myristate isopropyl, octyldodecyl myristate, coconut oil fatty acid butylene glycol, propylene glycol laurate, and diisostearyl malate. Silicones such as amino-modified silicone, alkyl-modified silicone, cyclic dimethyl silicone oil, silicone rubber, methylhydrogenpolysiloxane, methylphenylpolysiloxane, and methylpolysiloxane.

[0017] Examples of polyhydric alcohols include ethoxydiglycol, octanediol, polyglycerols such as glycerin, diethylene glycol and diglycerin, dipropylene glycol, 1,3-butylene glycol, propylene glycol, hexanediol, heptanediol, pentanediol, polyethylene glycol, and the like.

[0018] Examples of sugars include xylitol, sucrose, sorbitol, trehalose, lactose, fructose, maltitol, mannitol, and rhamnose.

[0019] Examples of the polymer compound include the following: Natural polymers such as Alcaligenes polysaccharides, alginic acid, casein, curdlan, carrageenan, agar, xanthan gum, chitosan, guar gum, quince seed, collagen, sclerotium gum, gelatin, dextrin, starch, hyaluronic acid, pullulan, pectin, and mannan. Natural polymer derivatives such as acetylated hyaluronic acid, ethyl cellulose, cationized guar gum, cationized cellulose, carboxymethyl cellulose, stearoxyhydroxypropyl methylcellulose, nitrocellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropyl methylcellulose, polyquaternium-10, polyquaternium-67, and methyl cellulose. Synthetic polymers such as POE-POP copolymer, alkyl acrylate copolymer, acrylic acid-acrylic acid amide-ethyl acrylate copolymer, acrylic resin alkanolamine, alkyl acrylate-vinyl acetate copolymer, acrylates copolymer Na, carboxyvinyl polymer, highly polymerized polyethylene glycol, polymeric silicone, silicone resin, (styrene / acrylates) copolymer, vinyl methyl ether-ethyl maleate copolymer, polyacrylic acid amide, polyacrylic acid sodium, polydimethylpiperidinium chloride, polyoxypropylene butyl ether, polyvinyl acetate, polyvinyl alcohol, and polyvinylpyrrolidone.

[0020] The surfactants include the following: Anionic surfactants such as acyl N-methyl taurine salts, POE alkyl ether carboxylates, POE alkyl ether sulfates, alkyl ether phosphate ester salts, alkylbenzenesulfonates, alkyl sulfate ester salts, N-acyl amino acid salts, α-olefin sulfonates, higher fatty acid soaps, sodium stearoyl glutamate, and sodium stearoyl lactylate. Cationic surfactants such as alkyltrimethylammonium chloride, dialkyldimethylammonium chloride, and benzalkonium chloride. Amphoteric surfactants such as alkylamidopropyldimethylaminoacetic acid betaine, alkylamidobetaine, 2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine, alkyldimethylaminoacetic acid betaine, hydrogenated lecithin, lysolecithin, and lecithin. POE Alkylamine / Fatty Acid Amide, POE Alkyl Ether, POE / POP Alkyl Ether Alkylamine Oxide, Alkyl Glucoside, PEG-6 Isostearate, Polyglyceryl-6 Isostearate, Ethoxydiglycol, PEG-8 Caprylic / Capric Glycerides, (Candelilla / Jojoba / Rice Bran) Polyglyceryl-3 Esters, Glycerin Fatty Acid Esters, POE Glycerin Fatty Acid Esters, Polyglyceryl-3 Diisostearate, Polyglyceryl-3 Dioleate, Polyglyceryl-6 Distearate, Fatty Acid Alkanolamides, PEG Fatty Acid Esters, PEG-40 Hydrogenated Castor Oil, Hydrogenated Sunflower Seed Oil Glyceryl Esters, Hydrogenated Sunflower Seed Oil Polyglyceryl-3 Esters, PEG-6 Stearate, PEG-32 Stearate, PEG Stearate Nonionic surfactants such as -75, glyceryl stearate, polyglyceryl-6 stearate, polyglyceryl-10 stearate, steareth-20, ceteth-20, sorbitan fatty acid esters, POE sorbitan fatty acid esters, POE sorbitan fatty acid esters, triisostearin PEG-6 esters, tribehenin PEG-20 esters, POE castor oil / hydrogenated castor oil, PEG-10 sunflower glycerides, glyceryl behenate, jojoba wax PEG-80 esters, jojoba wax PEG-120 esters, jojoba oil PEG-150 esters, polyoxyethylene beeswax, polyglyceryl-3 beeswax, polysorbate 80, polyglyceryl-6 polyhydroxystearate, polyglyceryl-6 polyricinoleate, PEG-16 macadamia glycerides, and PEG-8 beeswax.

[0021] Examples of coloring materials, powders, and particles include the following. Coloring materials such as inorganic pigments such as yellow iron oxide, carbon black, black iron oxide, red iron oxide, and ultramarine, pearl pigments, organic pigments, tar dyes, and natural dyes. Inorganic powders such as zinc oxide, alumina, (alumina / iron oxide / titanium oxide / mica) complex, (alumina / titanium oxide / sodium silicate / silica) complex, (alumina / titanium oxide / silica) complex, (alumina / titanium oxide / silica / dimethicone) complex, (alumina / silica) complex, (alumina / silica / talc) complex, mica, titanium mica, kaolin, magnesium aluminum silicate, titanium oxide, (titanium oxide / zirconium oxide / silica) complex, (titanium oxide / silica) complex, (titanium oxide / talc) complex, iron oxide, (iron oxide / titanium oxide / silica / mica) complex, (iron oxide / titanium oxide / mica) complex, (iron oxide / silica) complex, (iron oxide / silica / dimethicone) complex, silica, (silica / polyurethane-15 / mica) complex, (silica / mica) complex, zeolite, talc, hectorite, bentonite, mica, (mica / polyurethane-15) complex, and magnesium sodium silicate. Organic powders such as silk powder, cellulose powder, nylon powder, and polyethylene powder. Granules of fatty acid esters, cellulose, natural products, nylon, polyethylene, wax, etc.

[0022] Ingredients of natural origin include the following: Elastin, hydrolyzed casein, hydrolyzed keratin, hydrolyzed collagen, hydrolyzed silk, hydrolyzed soy protein, hydrolyzed pearl, chitin, chitosan, collagen, sodium chondroitin sulfate, water-soluble collagen, lactose, sodium hyaluronate, whey protein, peptides, and other substances of animal and microbial origin. Acacia Victoria Fruit Extract, Acacia Victoria Seed Extract, Actinidia Deliciosa Fruit Extract, Acronitia Acidula Fruit Extract, Asparagopsis Armata Extract, Acerola Fruit Extract, Anigozanthus Mangresi Flower Extract, Anigozanthus Flavidus Flower / Leaf Extract, Anetrea Anisata Leaf Extract, Alaria Esculenta Extract, Arctium Majus Root Extract, Arnica Montana Flower Extract, Aloe Ferox Leaf Extract, Aloe Vera Leaf Extract, Italian Cypress Leaf / Fruit / Stem Oil, Strawberry Fruit Extract, Ginkgo Biloba Leaf Extract, Iris Root Extract, Witha Nia somnifera root extract, Urtica dioica extract, Uva-ursi leaf extract, Ecklonia radiata extract, Rubus rubra fruit extract, Barley bark extract, Oriental thistle flower / leaf / stem extract, Barley seed extract, Panax ginseng root extract, Lamium extract, Amaranth flower extract, Orange fruit extract, Orange fruit water, Chamomile flower extract, Chamomilla recutita (matricaria) extract, Hydrolyzed wheat protein, Hydrolyzed soy protein, Oat kernel extract, Guarana seed extract, Carrot extract, Beta-carotene, Licorice root extract, Rubus idaeus extract, Rubus idaeus fruit Fruit extract, kiwi fruit extract, kiwi fruit water, Kigelia africana fruit extract, Yellow Amaranth extract, Caviar lime extract, Cucumber fruit extract, Leptospermum officinalis branch / leaf extract, Quillaja bark extract, Guava fruit extract, Wolfberry fruit extract, Sophora flavescens root extract, Cranberry fruit water, Grevillea speciosa flower extract, Grapefruit fruit water, Kunzea pomifera fruit extract, Caper fruit extract, Coconut water, Yeast extract, Rice bran water, Viola tricolor extract, Zanthoxylum piperitum seed extract, Santalum acuminatum fruit extract, Lithospermum root extract Ingredients: Syzygium reumanii fruit extract, Citrus glauca fruit extract, Ginger water, Birch extract, Horsetail extract, Japanese cedar bud extract, Black cherry fruit water, Spirulina platensis extract, Ivy leaf / stem extract, Horse chestnut seed extract, Ash bark extract, Sambucus nigra flower extract, Yarrow extract, Peppermint extract, Sage leaf extract, Mallow flower / leaf / stem extract, Rosa centifolia flower extract, Jasminum officinale flower / leaf extract, Tasmannia lanceolata fruit extract, Tasmannia lanceolata fruit / leaf extract,Davidsonia pruriens fruit extract, dulse extract, tea leaf extract, passionflower flower extract, centella asiatica extract, tea tree leaf extract, tea tree leaf oil, terminalia ferdinandiana fruit extract, angelica extract, calendula officinalis flower extract, carrot extract, tomato fruit / leaf / stem extract, kaede root extract, carrot root extract, garlic root extract, pineapple fruit extract, hibiscus flower extract, bakuchiol, bakuhousia Anisata leaf extract, Bakhousia citriodora leaf extract, Lotus root water, Lotus flower extract, Papaya fruit extract, Hamamelis virginiana extract, Hamamelis virginiana bark / leaf / branch extract, Chayote fruit extract, Banksia serrata flower extract, Bambusa arundinacea stem, Daisy flower extract, Hinokitiol, Fucus vesiculosus extract, Himantaria elongata extract, Loquat leaf extract, Grape fruit water, Grape leaf extract, Beech tree seedling extract, Plumeria flower extract, Playogini Umtimolense Fruit Extract, Luffa Extract, Safflower Extract, Cucurbita Pepo Fruit Extract, Persian Walnut Seed Extract, Henna Flower / Fruit / Leaf Extract, Podocarpus Elatus Fruit Extract, Madake Extract, Mangifera Indica (Mango) Fruit Extract, Microcitrus Australasica Fruit Extract, Microcitrus Austrilis Fruit Extract, Mimosa Tenuiflora Bark Extract, Pufferfish Bamboo Shoot Water, Peach Leaf Extract, Cornflower Flower Extract, Vegetable Oil, Willow Herb Flower / Leaf / Stem extract, eucalyptus extract, European birch bark extract, European beech bud extract, Ranunculus ficaria extract, Laventula hybrida oil, Labdanum oil, lavender flower / leaf / stem extract, apple fruit extract, apple fruit water, Rumex occidentalis extract, lemon fruit extract, lemon fruit water, lemon myrtle leaf, rose water, rosemary leaf extract, lowbush blueberry fruit extract, wine extract, and other plant-based origins. Mineral origins such as extracts of olivine, malachite, hematite, smithsonite, rhodochrosite, etc.

[0023] Examples of disinfectants and preservatives include: Benzoic acid and its salts, benzalkonium chloride, isopropylmethylphenol, chlorhexidine, salicylic acid and its salts, zinc pyrithione, sorbic acid and its salts, dehydroacetic acid and its salts, triclosan, 4-terpineol, trichlorocarbanilide, parahydroxybenzoic acid esters (methylparaben, ethylparaben, butylparaben, etc.), piroctone olamine, phenoxyethanol, hexachlorophene, methylisothiazolinone, methylchloroisothiazolinone, etc.

[0024] Antioxidants include the following: Sodium bisulfite, vitamin C and its derivatives, vitamin E (tocopherols), butylhydroxyanisole, butylhydroxytoluene, gallic acid esters, etc. Antioxidant aids such as ascorbic acid, citric acid, cephalin, succinic acid, phytic acid, malonic acid, maleic acid, phosphoric acid, etc.

[0025] Examples of sequestering agents include: edetate, citrate, hydroxyethanediphosphonate, phytic acid, malate, etc.

[0026] Examples of UV protection agents include the following: Examples of suitable antiperspirants include urocanic acid, ethylhexyl triazone, octocrylene, ethylhexyl salicylate, diethylaminohydroxybenzoylhexyl benzoate, para-aminobenzoic acid, octyl paradimethylaminobenzoate, bisethylhexyloxyphenol methoxyphenyl triazine, 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid, phenylbenzimidazole sulfonic acid, t-butyl methoxydibenzoylmethane, homosalate, polysilicone-15, methylenebisbenzotriazolyltetramethylbutylphenol, ethylhexyl methoxycinnamate, and 2-methylphenyl 4-methoxycinnamate.

[0027] Examples of pH adjusters include the following: Organic and inorganic alkaline agents such as aminomethylpropanol, aminomethylpropanediol, ammonia water, potassium hydroxide, sodium hydroxide, sodium carbonate, triethanolamine, tromethamine, monoethanolamine, and arginine. Organic and inorganic acids such as citric acid, lactic acid, phosphoric acid, malic acid, and HCl.

[0028] The various physiologically active ingredients include the following: To prevent rough skin, it contains polyhydric alcohols such as glycerin and POE methyl glucoside, and sugars such as trehalose and pullulan. Biopolymers such as elastin, chitin / chitosan, sodium chondroitin sulfate, and sodium hyaluronate. Moisturizers such as amino acids, sodium lactate, urea, betaine, and PCA-Na. Lipid components such as cholesterol, sphingolipids, ceramides, and phospholipids. Anti-inflammatory agents such as ε-aminocaproic acid, allantoin, lysozyme chloride, guaiazulene, glycyrrhizinic acid derivatives, β-glycyrrhetinic acid, and hydrocortisone. Other ingredients include allantoin and antihistamines. Various UV protection agents for anti-aging purposes. Antioxidants such as acetylcysteine, oxothiazolidine, ethylbisiminomethylguaiacol manganese chloride, caffeic acid derivatives, carotenoids, glutathione, tannins, vitamins (B2, C, E), hydroxyethylmethylthiopropenamide, flavonoids, ubiquinone, lignans, and lycopene. Cell activators such as alpha-hydroxy acids. Blood flow promoters such as gamma-oryzanol and vitamin E and its derivatives. For the purpose of whitening, derivatives of vitamin C, sodium ascorbate, magnesium ascorbyl phosphate, ascorbic acid glucoside, etc. Melanin inhibitors such as arbutin, ellagic acid, kojic acid, linoleic acid, linolenic acid, lactic acid, tranexamic acid, etc. Other ingredients include aminoethylphosphinic acids, sulfur, glutathione, placenta extract, etc. Alpha-hydroxy acids such as citric acid, glycolic acid, tartaric acid, lactic acid, and malic acid, and retinoids (vitamin A derivatives) for the purpose of preventing wrinkles. For hair growth, vasodilators such as capronium chloride and nicotinic acid benzyl ester, local stimulants such as capsicum tincture and ginger tincture, female hormones such as estradiol and ethinylestradiol, and sebum secretion inhibitors such as pyridoxine hydrochloride. Climbazole, zinc pyrithione, piroctone olamine, etc. are used to prevent dandruff and itching. For the purpose of preventing acne, keratolytic and exfoliating agents such as sulfur, salicylic acid, and resorcinol, and disinfectants such as benzalkonium chloride and halocarban. Antiperspirants such as aluminum chloride, aluminum chlorohydrate, and zinc oxide are used to prevent underarm odor. For the purpose of various other physiological activities, vitamins such as pantothenic acid, pantethine, vitamin A and its derivatives, nicotinamide, vitamin B2 and its derivatives, vitamin B6 hydrochloride, vitamin B6 dioctanoate, vitamin B6 tripalmitate, vitamin B12, vitamin B15 and its derivatives, vitamin C such as ascorbic acid, ascorbic acid dipalmitate, ascorbic acid phosphate ester (salt), vitamin D, vitamin E such as α-tocopherol, β-tocopherol, γ-tocopherol, vitamin E acetate, vitamin E nicotinate, and vitamin H are also included. Amino acids and their derivatives, such as asparagine, aspartic acid, acetylcitrullamidoarginine, alanine, arginine, carboxyethylaminobutyric acid, glycine, glutamylamidoethylimidazole, glutamylamidoethylindole, glutamine, serine, taurine, tyrosine, decarboxycarnosine HCl, threonine, valine, histidine, hydroxyproline, pyroglutamylamidoethylindole, phenylalanine, prolinamidoethylindole, methylpropylamidoacetylmethionine, and leucine. Protein-related substances, such as acetyl tetrapeptide-2, acetyl hexapeptide-1, trifluoroacetyl tripeptide-2, tripeptide-1, nanopeptide-1, and palmitoylpeptide-1. Silanol derivatives such as ascorbyl methylsilanol pectin, aspartic acid methylsilanol hydroxyproline, alginic acid siloxanetriol, glutamic acid silanediol, salicylic acid silanediol, dioleyl tocopheryl methylsilanol, dimethyl oxobenzodioxasilane, silanetriol, silanetriol alginate, silanetriol trehalose ether, hyaluronic acid dimethylsilanol, polysilicone-3, methylsilanol acetyl tyrosine, methylsilanol sodium lactate, mannuronate acefylline methylsilanol, mannuronate methylsilanol, lysine silanetriol, PCA copper methylsilanol, and slimming-related ingredients such as caffeine and dulse extract.

[0029] The formulation of the topical skin composition of the present invention can be in the form usually used for topical skin compositions, such as liquid, emulsion, cream, gel, mist, aerosol foam, solid, or powder dispersion. [Example]

[0030] The present invention will now be described in more detail with reference to examples. However, the present invention is not limited to these examples. The blending amounts are expressed in mass % unless otherwise specified.

[0031] Example 1 Table 1 shows an example of the emulsion formulation. [Table 1] *1) Synobear HR: (Siseon product) Hexylresorcinol

[0032] Example 2 Table 2 shows an example of the formulation of an oil beauty serum. [Table 2]

[0033] Example 3 Table 3 shows an example of a skin care cream (O / W) formulation. [Table 3]

[0034] Example 4 Table 4 illustrates a skin care gel formulation. [Table 4] *2) Lecigel: (Lucas Meyer Cosmetics product) Lecithin, acrylates copolymer Na [Industrial Applicability]

[0035] The present invention can be widely used in the industries of producing and selling external preparation compositions such as cosmetics, quasi-drugs, and pharmaceuticals.

Claims

1. A skin topical composition containing hexylresorcinol.

2. 2. The external preparation composition for skin according to claim 1, wherein the content of hexylresorcinol is 0.01 to 5.0% by mass.

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