External skin preparation composition
Incorporating sea buckthorn leaf extract into topical skin compositions enhances endothelial barrier function, addressing the issues of dark circles and bags under the eyes by preventing cell migration and promoting healthy skin.
Patent Information
- Application Number
- JP2024097038
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- Filing Date
- 2024-05-30
- Publication Date
- 2025-12-11
AI Technical Summary
Existing topical skin preparations have not satisfactorily addressed the issues of dark circles and bags under the eyes, primarily due to inadequate promotion of blood flow and endothelial barrier function.
Incorporation of sea buckthorn leaf extract into topical skin compositions to enhance endothelial barrier function, preventing red blood cell and leukocyte migration, thereby reducing pigmentation and edema.
The sea buckthorn leaf extract effectively suppresses the occurrence of dark circles and bags under the eyes by maintaining tight junctions and improving skin health.
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Figure 2025181551000001_ABST
Abstract
Description
[Technical Field]
[0001] The present invention relates to a topical skin composition containing an extract of sea buckthorn leaves. Here, the topical skin composition refers to skin care cosmetics such as face washes, lotions, creams, and packs, makeup cosmetics such as foundations, lipsticks, and mascaras, body care cosmetics such as body soaps, slimming agents, UV protection agents, bath additives, and antiperspirants, and fragrance cosmetics such as perfumes and colognes, and also includes legal cosmetics, quasi-drugs, and pharmaceuticals. [Background technology]
[0002] Dark circles and bags around the eyes are caused by a variety of factors, including poor circulation due to lack of sleep and fatigue, and are not desirable from a cosmetic standpoint.
[0003] Dark circles are caused by poor blood flow, while bags under the eyes are also caused by sagging skin due to aging. However, when abnormalities in microcirculation occur due to stress such as fatigue, white blood cells and red blood cells migrate out of the blood vessels from the tight junctions that connect cells, leading to the development of dark circles due to pigmentation and edema (bags under the eyes).
[0004] To promote blood flow, Patent Document 1 discloses a method for improving congestion and eliminating dark circles and dullness under the eyes using vitamin K. Patent Document 2 also discloses a method for eliminating sagging eye bags using cosmetics containing water-absorbent resins that contain polysaccharides as structural units. [Prior art documents] [Patent documents]
[0005] [Patent Document 1] Japanese Patent Application Laid-Open No. 2004-51627 [Patent Document 2] Japanese Patent Application Publication No. 2018-43971 DISCLOSURE OF THE INVENTION [Problem to be solved by the invention]
[0006] Against this background, research into ingredients that improve dark circles and bags around the eyes has progressed, and topical skin preparations have been developed, but the effects have not necessarily been satisfactory. [Means for solving the problem]
[0007] The present invention has been made under the above circumstances, and provides a novel skin topical composition that improves endothelial barrier function and prevents the development of dark circles and bags around the eyes by incorporating an extract of sea buckthorn leaves.
[0008] The first aspect of the present invention is a skin external preparation composition characterized by containing an extract of sea buckthorn leaves.
[0009] Claim 2 of the present invention provides the composition for external use on skin according to claim 1, in which the extract of sea buckthorn leaves is 0.01 to 95.0% by mass. [Effects of the Invention]
[0010] The extract of sea buckthorn leaves of the present invention enhances endothelial barrier function and prevents red blood cell migration, which causes pigmentation, and leukocyte migration, which causes edema, and therefore, when incorporated into an external preparation composition, is effective in suppressing the occurrence of dark circles and bags around the eyes. [Brief explanation of the drawings]
[0011] [Figure 1] Figure 1 shows the effect of the sea buckthorn leaf extract of the present invention on improving endothelial barrier function. When monolayer cultures of human dermal microvascular endothelial cells were stressed with TNF-α, treatment with the commercially available sea buckthorn leaf extract showed an increase in TEER, indicating that tight junctions were sufficiently formed and barrier function was maintained. DETAILED DESCRIPTION OF THE INVENTION
[0012] The present invention is described in detail below. The origin of the sea buckthorn used in the present invention and the method for producing the sea buckthorn leaf extract are not particularly limited, but it is preferable to use sea buckthorn leaves harvested in Canada. It is essential that the extract contains triterpenoid acids, triterpene alcohols, phytosterols, unsaturated fatty acids, tocochromanol, aliphatic esters, aliphatic alcohols, and mineral components. This sea buckthorn leaf extract is available as a solution mixed with octyldodecyl myristate as a commercial raw material called "Eyeglorius" from GATTEFOSSE SAS, France.
[0013] The amount of sea buckthorn leaf extract of the present invention is 0.01 to 95.0% by mass, preferably 0.1 to 10.0% by mass, of the total amount of the topical skin composition prepared using the commercially available raw materials. When preparing a typical topical skin composition, if the amount is less than 0.01% by mass, the effect of suppressing the occurrence of dark circles and bags around the eyes by improving the endothelial barrier function is not achieved. Although it is conceivable to incorporate an extract in an amount exceeding 10.0% by mass up to 95.0% by mass, this is not preferred because the effect commensurate with the amount incorporated gradually saturates.
[0014] The effect of the topical skin preparation composition of the present invention is to prevent the occurrence of dark circles and bags under the eyes, leading to a youthful and healthy skin. Therefore, further effects can be expected by adding a moisturizing component or a component with a blood flow promoting effect to the topical skin preparation composition of the present invention. Such components include vitamin C and its derivatives, nicotinamide, hyaluronic acid, plant extracts, etc.
[0015] In addition to the essential ingredients described above, the topical skin preparation composition of the present invention may contain other ingredients that are typically used in topical skin preparation compositions such as cosmetics and pharmaceuticals. Examples of such other ingredients include the following. The topical skin preparation composition of the present invention is produced by blending one or more of these ingredients with the essential ingredients described above according to a conventional method.
[0016] The oily components include the following: Avocado oil, apricot kernel oil, olive oil, cocoa butter, beef tallow, sesame oil, wheat germ oil, camellia oil, safflower oil, hydrogenated moringa oil, soybean oil, tea seed oil, evening primrose oil, camellia oil, glycolipids, triglyceride (C10-18) glyceryl triphosphate, peppermint leaf oil, palm kernel oil, palm oil, castor oil, sunflower seed oil, boswellia serrata oil, macadamia seed oil, manuka oil, horse fat, melia azadirachta seed oil, cottonseed oil, Japan wax, (moringa oil / hydrogenated moringa oil) esters, coconut oil, lemon fruit oil, phospholipids, horseradish perilla seed oil, etc. Waxes such as carnauba wax, candelilla wax, rice bran wax, hydrogenated jojoba oil, sunflower seed wax, acacia dealbata flower wax, partially hydrogenated jojoba oil, jojoba ester, jojoba seed oil, beeswax, and lanolin. Hydrocarbons such as isoparaffin, hydrogenated polyisobutene, squalane, squalene, ceresin, paraffin, microcrystalline wax, liquid paraffin, and petrolatum. Higher fatty acids such as isostearic acid, oleic acid, stearic acid, palmitic acid, hydroxystearic acid, behenic acid, myristic acid, lauric acid, linoleic acid, and linolenic acid. Higher alcohols such as isostearyl alcohol, 2-octyldodecanol, oleyl alcohol, cholesterol, stearyl alcohol, cetyl alcohol, cetearyl alcohol, soybean sterol, phytosterols, behenyl alcohol, jojoba alcohol, myristyl alcohol, and lanolin alcohol. Alkyl glyceryl ethers such as chimyl alcohol and batyl alcohol. Isostearyl Isostearate, Phytostearyl Isostearate, Propylene Glycol Isostearate, Cetyl 2-Ethylhexanoate, Ethoxydiglycol Behenate, Ethoxydiglycol Oleate, Hydrolyzed Jojoba Esters, Triethyl Citrate, Diethylene Glycol Monoethyl Ether, Glycol Distearate, Propylene Glycol Dinonanoate, Cholesteryl Stearate, Stearyl Stearate, Caprylic / Capric Triglyceride, Triheptanoin, Tri-2- Esters such as glyceryl hexanoate, ethylhexyl palmitate, (behenic acid / oleic acid) (behenyl / oleyl) esters, pentaerythritol tetraester, jojoba fatty acid isopropyl, (jojoba oil / macadamia seed oil) esters, macadamiate ethyl, macadamiate phytosteryl, myristate isopropyl, octyldodecyl myristate, coconut oil fatty acid butylene glycol, propylene glycol laurate, and diisostearyl malate. Silicones such as amino-modified silicone, alkyl-modified silicone, cyclic dimethyl silicone oil, silicone rubber, methylhydrogenpolysiloxane, methylphenylpolysiloxane, and methylpolysiloxane.
[0017] Examples of polyhydric alcohols include ethoxydiglycol, octanediol, polyglycerols such as glycerin, diethylene glycol and diglycerin, dipropylene glycol, 1,3-butylene glycol, propylene glycol, hexanediol, heptanediol, pentanediol, polyethylene glycol, and the like.
[0018] Examples of sugars include xylitol, sucrose, sorbitol, trehalose, lactose, fructose, maltitol, mannitol, and rhamnose.
[0019] Examples of the polymer compound include the following: Natural polymers such as Alcaligenes polysaccharides, alginic acid, casein, curdlan, carrageenan, agar, xanthan gum, chitosan, guar gum, quince seed, collagen, sclerotium gum, gelatin, dextrin, starch, hyaluronic acid, pullulan, pectin, and mannan. Natural polymer derivatives such as acetylated hyaluronic acid, ethyl cellulose, cationized guar gum, cationized cellulose, carboxymethyl cellulose, stearoxyhydroxypropyl methylcellulose, nitrocellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropyl methylcellulose, polyquaternium-10, polyquaternium-67, and methyl cellulose. Synthetic polymers such as POE-POP copolymer, alkyl acrylate copolymer, acrylic acid-acrylic acid amide-ethyl acrylate copolymer, acrylic resin alkanolamine, alkyl acrylate-vinyl acetate copolymer, acrylates copolymer Na, carboxyvinyl polymer, highly polymerized polyethylene glycol, polymeric silicone, silicone resin, (styrene / acrylates) copolymer, vinyl methyl ether-ethyl maleate copolymer, polyacrylic acid amide, polyacrylic acid sodium, polydimethylpiperidinium chloride, polyoxypropylene butyl ether, polyvinyl acetate, polyvinyl alcohol, and polyvinylpyrrolidone.
[0020] The surfactants include the following: Anionic surfactants such as acyl N-methyl taurine salts, POE alkyl ether carboxylates, POE alkyl ether sulfates, alkyl ether phosphate ester salts, alkylbenzenesulfonates, alkyl sulfate ester salts, N-acyl amino acid salts, α-olefin sulfonates, higher fatty acid soaps, sodium stearoyl glutamate, and sodium stearoyl lactylate. Cationic surfactants such as alkyltrimethylammonium chloride, dialkyldimethylammonium chloride, and benzalkonium chloride. Amphoteric surfactants such as alkylamidopropyldimethylaminoacetic acid betaine, alkylamidobetaine, 2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine, alkyldimethylaminoacetic acid betaine, hydrogenated lecithin, lysolecithin, and lecithin. POE Alkylamine / Fatty Acid Amide, POE Alkyl Ether, POE / POP Alkyl Ether Alkylamine Oxide, Alkyl Glucoside, PEG-6 Isostearate, Polyglyceryl-6 Isostearate, Ethoxydiglycol, PEG-8 Caprylic / Capric Glycerides, (Candelilla / Jojoba / Rice Bran) Polyglyceryl-3 Esters, Glycerin Fatty Acid Esters, POE Glycerin Fatty Acid Esters, Polyglyceryl-3 Diisostearate, Polyglyceryl-3 Dioleate, Polyglyceryl-6 Distearate, Fatty Acid Alkanolamides, PEG Fatty Acid Esters, PEG-40 Hydrogenated Castor Oil, Hydrogenated Sunflower Seed Oil Glyceryl Esters, Hydrogenated Sunflower Seed Oil Polyglyceryl-3 Esters, PEG-6 Stearate, PEG-32 Stearate, PEG Stearate Nonionic surfactants such as -75, glyceryl stearate, polyglyceryl-6 stearate, polyglyceryl-10 stearate, steareth-20, ceteth-20, sorbitan fatty acid esters, POE sorbitan fatty acid esters, POE sorbitan fatty acid esters, triisostearin PEG-6 esters, tribehenin PEG-20 esters, POE castor oil / hydrogenated castor oil, PEG-10 sunflower glycerides, glyceryl behenate, jojoba wax PEG-80 esters, jojoba wax PEG-120 esters, jojoba oil PEG-150 esters, polyoxyethylene beeswax, polyglyceryl-3 beeswax, polysorbate 80, polyglyceryl-6 polyhydroxystearate, polyglyceryl-6 polyricinoleate, PEG-16 macadamia glycerides, and PEG-8 beeswax.
[0021] Examples of coloring materials, powders, and particles include the following. Coloring materials such as inorganic pigments such as yellow iron oxide, carbon black, black iron oxide, red iron oxide, and ultramarine, pearl pigments, organic pigments, tar dyes, and natural dyes. Inorganic powders such as zinc oxide, alumina, (alumina / iron oxide / titanium oxide / mica) complex, (alumina / titanium oxide / sodium silicate / silica) complex, (alumina / titanium oxide / silica) complex, (alumina / titanium oxide / silica / dimethicone) complex, (alumina / silica) complex, (alumina / silica / talc) complex, mica, titanium mica, kaolin, magnesium aluminum silicate, titanium oxide, (titanium oxide / zirconium oxide / silica) complex, (titanium oxide / silica) complex, (titanium oxide / talc) complex, iron oxide, (iron oxide / titanium oxide / silica / mica) complex, (iron oxide / titanium oxide / mica) complex, (iron oxide / silica) complex, (iron oxide / silica / dimethicone) complex, silica, (silica / polyurethane-15 / mica) complex, (silica / mica) complex, zeolite, talc, hectorite, bentonite, mica, (mica / polyurethane-15) complex, and magnesium sodium silicate. Organic powders such as silk powder, cellulose powder, nylon powder, and polyethylene powder. Granules of fatty acid esters, cellulose, natural products, nylon, polyethylene, wax, etc.
[0022] Ingredients of natural origin include the following: Elastin, hydrolyzed casein, hydrolyzed keratin, hydrolyzed collagen, hydrolyzed silk, hydrolyzed soy protein, hydrolyzed pearl, chitin, chitosan, collagen, sodium chondroitin sulfate, water-soluble collagen, lactose, sodium hyaluronate, whey protein, peptides, and other substances of animal and microbial origin. Acacia Victoria Fruit Extract, Acacia Victoria Seed Extract, Actinidia Deliciosa Fruit Extract, Acronitia Acidula Fruit Extract, Asparagopsis Armata Extract, Acerola Fruit Extract, Anigozanthus Mangresi Flower Extract, Anigozanthus Flavidus Flower / Leaf Extract, Anetrea Anisata Leaf Extract, Alaria Esculenta Extract, Arctium Majus Root Extract, Arnica Montana Flower Extract, Aloe Ferox Leaf Extract, Aloe Vera Leaf Extract, Italian Cypress Leaf / Fruit / Stem Oil, Strawberry Fruit Extract, Ginkgo Biloba Leaf Extract, Iris Root Extract, Witha Nia somnifera root extract, Urtica dioica extract, Uva-ursi leaf extract, Ecklonia radiata extract, Rubus rubra fruit extract, Barley bark extract, Oriental thistle flower / leaf / stem extract, Barley seed extract, Panax ginseng root extract, Lamium extract, Amaranth flower extract, Orange fruit extract, Orange fruit water, Chamomile flower extract, Chamomilla recutita (matricaria) extract, Hydrolyzed wheat protein, Hydrolyzed soy protein, Oat kernel extract, Guarana seed extract, Carrot extract, Beta-carotene, Licorice root extract, Rubus idaeus extract, Rubus idaeus fruit Fruit extract, kiwi fruit extract, kiwi fruit water, Kigelia africana fruit extract, Yellow Amaranth extract, Caviar lime extract, Cucumber fruit extract, Leptospermum officinalis branch / leaf extract, Quillaja bark extract, Guava fruit extract, Wolfberry fruit extract, Sophora flavescens root extract, Cranberry fruit water, Grevillea speciosa flower extract, Grapefruit fruit water, Kunzea pomifera fruit extract, Caper fruit extract, Coconut water, Yeast extract, Rice bran water, Viola tricolor extract, Zanthoxylum piperitum seed extract, Santalum acuminatum fruit extract, Lithospermum root extract Ingredients: Syzygium reumanii fruit extract, Citrus glauca fruit extract, Ginger water, Birch extract, Horsetail extract, Japanese cedar bud extract, Black cherry fruit water, Spirulina platensis extract, Ivy leaf / stem extract, Horse chestnut seed extract, Ash bark extract, Sambucus nigra flower extract, Yarrow extract, Peppermint extract, Sage leaf extract, Mallow flower / leaf / stem extract, Rosa centifolia flower extract, Jasminum officinale flower / leaf extract, Tasmannia lanceolata fruit extract, Tasmannia lanceolata fruit / leaf extract,Davidsonia pruriens fruit extract, dulse extract, tea leaf extract, passionflower flower extract, centella asiatica extract, tea tree leaf extract, tea tree leaf oil, terminalia ferdinandiana fruit extract, angelica extract, calendula officinalis flower extract, carrot extract, tomato fruit / leaf / stem extract, kaede root extract, carrot root extract, garlic root extract, pineapple fruit extract, hibiscus flower extract, bakuchiol, bakuhousia Anisata leaf extract, Bakhousia citriodora leaf extract, Lotus root water, Lotus flower extract, Papaya fruit extract, Hamamelis virginiana extract, Hamamelis virginiana bark / leaf / branch extract, Chayote fruit extract, Banksia serrata flower extract, Bambusa arundinacea stem, Daisy flower extract, Hinokitiol, Fucus vesiculosus extract, Himantaria elongata extract, Loquat leaf extract, Grape fruit water, Grape leaf extract, Beech tree seedling extract, Plumeria flower extract, Playogini Umtimolense Fruit Extract, Luffa Extract, Safflower Extract, Cucurbita Pepo Fruit Extract, Persian Walnut Seed Extract, Henna Flower / Fruit / Leaf Extract, Podocarpus Elatus Fruit Extract, Madake Extract, Mangifera Indica (Mango) Fruit Extract, Microcitrus Australasica Fruit Extract, Microcitrus Austrilis Fruit Extract, Mimosa Tenuiflora Bark Extract, Pufferfish Bamboo Shoot Water, Peach Leaf Extract, Cornflower Flower Extract, Vegetable Oil, Willow Herb Flower / Leaf / Stem extract, eucalyptus extract, European birch bark extract, European beech bud extract, Ranunculus ficaria extract, Laventula hybrida oil, Labdanum oil, lavender flower / leaf / stem extract, apple fruit extract, apple fruit water, Rumex occidentalis extract, lemon fruit extract, lemon fruit water, lemon myrtle leaf, rose water, rosemary leaf extract, lowbush blueberry fruit extract, wine extract, and other plant-based origins. Mineral origins such as extracts of olivine, malachite, hematite, smithsonite, rhodochrosite, etc.
[0023] Examples of disinfectants and preservatives include: Benzoic acid and its salts, benzalkonium chloride, isopropylmethylphenol, chlorhexidine, salicylic acid and its salts, zinc pyrithione, sorbic acid and its salts, dehydroacetic acid and its salts, triclosan, 4-terpineol, trichlorocarbanilide, parahydroxybenzoic acid esters (methylparaben, ethylparaben, butylparaben, etc.), piroctone olamine, phenoxyethanol, hexachlorophene, methylisothiazolinone, methylchloroisothiazolinone, etc.
[0024] Antioxidants include the following: Sodium bisulfite, vitamin C and its derivatives, vitamin E (tocopherols), butylhydroxyanisole, butylhydroxytoluene, gallic acid esters, etc. Antioxidant aids such as ascorbic acid, citric acid, cephalin, succinic acid, phytic acid, malonic acid, maleic acid, phosphoric acid, etc.
[0025] Examples of sequestering agents include: edetate, citrate, hydroxyethanediphosphonate, phytic acid, malate, etc.
[0026] Examples of UV protection agents include the following: Examples of suitable antiperspirants include urocanic acid, ethylhexyl triazone, octocrylene, ethylhexyl salicylate, diethylaminohydroxybenzoylhexyl benzoate, para-aminobenzoic acid, octyl paradimethylaminobenzoate, bisethylhexyloxyphenol methoxyphenyl triazine, 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid, phenylbenzimidazole sulfonic acid, t-butyl methoxydibenzoylmethane, homosalate, polysilicone-15, methylenebisbenzotriazolyltetramethylbutylphenol, ethylhexyl methoxycinnamate, and 2-methylphenyl 4-methoxycinnamate.
[0027] Examples of pH adjusters include the following: Organic and inorganic alkaline agents such as aminomethylpropanol, aminomethylpropanediol, ammonia water, potassium hydroxide, sodium hydroxide, sodium carbonate, triethanolamine, tromethamine, monoethanolamine, and arginine. Organic and inorganic acids such as citric acid, lactic acid, phosphoric acid, malic acid, and HCl.
[0028] The various physiologically active ingredients include the following: To prevent rough skin, it contains polyhydric alcohols such as glycerin and POE methyl glucoside, and sugars such as trehalose and pullulan. Biopolymers such as elastin, chitin / chitosan, sodium chondroitin sulfate, and sodium hyaluronate. Moisturizers such as amino acids, sodium lactate, urea, betaine, and PCA-Na. Lipid components such as cholesterol, sphingolipids, ceramides, and phospholipids. Anti-inflammatory agents such as ε-aminocaproic acid, allantoin, lysozyme chloride, guaiazulene, glycyrrhizinic acid derivatives, β-glycyrrhetinic acid, and hydrocortisone. Other ingredients include allantoin and antihistamines. Various UV protection agents for anti-aging purposes. Antioxidants such as acetylcysteine, oxothiazolidine, ethylbisiminomethylguaiacol manganese chloride, caffeic acid derivatives, carotenoids, glutathione, tannins, vitamins (B2, C, E), hydroxyethylmethylthiopropenamide, flavonoids, ubiquinone, lignans, and lycopene. Cell activators such as alpha-hydroxy acids. Blood flow promoters such as gamma-oryzanol and vitamin E and its derivatives. For the purpose of whitening, derivatives of vitamin C, sodium ascorbate, magnesium ascorbyl phosphate, ascorbic acid glucoside, etc. Melanin inhibitors such as arbutin, ellagic acid, kojic acid, linoleic acid, linolenic acid, lactic acid, tranexamic acid, etc. Other ingredients include aminoethylphosphinic acids, sulfur, glutathione, placenta extract, etc. Alpha-hydroxy acids such as citric acid, glycolic acid, tartaric acid, lactic acid, and malic acid, and retinoids (vitamin A derivatives) for the purpose of preventing wrinkles. For hair growth, vasodilators such as capronium chloride and nicotinic acid benzyl ester, local stimulants such as capsicum tincture and ginger tincture, female hormones such as estradiol and ethinylestradiol, and sebum secretion inhibitors such as pyridoxine hydrochloride. Climbazole, zinc pyrithione, piroctone olamine, etc. are used to prevent dandruff and itching. For the purpose of preventing acne, keratolytic and exfoliating agents such as sulfur, salicylic acid, and resorcinol, and disinfectants such as benzalkonium chloride and halocarban. Antiperspirants such as aluminum chloride, aluminum chlorohydrate, and zinc oxide are used to prevent underarm odor. For the purpose of various other physiological activities, vitamins such as pantothenic acid, pantethine, vitamin A and its derivatives, nicotinamide, vitamin B2 and its derivatives, vitamin B6 hydrochloride, vitamin B6 dioctanoate, vitamin B6 tripalmitate, vitamin B12, vitamin B15 and its derivatives, vitamin C such as ascorbic acid, ascorbic acid dipalmitate, ascorbic acid phosphate ester (salt), vitamin D, vitamin E such as α-tocopherol, β-tocopherol, γ-tocopherol, vitamin E acetate, vitamin E nicotinate, and vitamin H are also included. Amino acids and their derivatives, such as asparagine, aspartic acid, acetylcitrullamidoarginine, alanine, arginine, carboxyethylaminobutyric acid, glycine, glutamylamidoethylimidazole, glutamylamidoethylindole, glutamine, serine, taurine, tyrosine, decarboxycarnosine HCl, threonine, valine, histidine, hydroxyproline, pyroglutamylamidoethylindole, phenylalanine, prolinamidoethylindole, methylpropylamidoacetylmethionine, and leucine. Protein-related substances, such as acetyl tetrapeptide-2, acetyl hexapeptide-1, trifluoroacetyl tripeptide-2, tripeptide-1, nanopeptide-1, and palmitoylpeptide-1. Silanol derivatives such as ascorbyl methylsilanol pectin, aspartic acid methylsilanol hydroxyproline, alginic acid siloxanetriol, glutamic acid silanediol, salicylic acid silanediol, dioleyl tocopheryl methylsilanol, dimethyl oxobenzodioxasilane, silanetriol, silanetriol alginate, silanetriol trehalose ether, hyaluronic acid dimethylsilanol, polysilicone-3, methylsilanol acetyl tyrosine, methylsilanol sodium lactate, mannuronate acefylline methylsilanol, mannuronate methylsilanol, lysine silanetriol, PCA copper methylsilanol, and slimming-related ingredients such as caffeine and dulse extract.
[0029] The formulation of the topical skin composition of the present invention can be in the form usually used for topical skin compositions, such as liquid, emulsion, cream, gel, mist, aerosol foam, solid, or powder dispersion. [Example]
[0030] The present invention will now be described in more detail with reference to examples. However, the present invention is not limited to these examples. The blending amounts are expressed in mass % unless otherwise specified.
[0031] Example 1 Table 1 shows an example of the formulation of a skin care cream (W / O). [Table 1]
[0032] Example 2 Table 2 shows an example of a skin care cream (O / W) formulation. [Table 2]
[0033] Example 3 Table 3 shows an example of the formulation of an oil beauty serum. [Table 3]
[0034] Example 4 Table 4 illustrates a skin care gel formulation. [Table 4]
[0035] Example 5 Table 5 shows an example of a cleansing cream formulation. [Table 5] [Industrial Applicability]
[0036] The present invention can be widely used in the industries of producing and selling external preparation compositions such as cosmetics, quasi-drugs, and pharmaceuticals.
Claims
1. A skin external preparation composition comprising an extract of sea buckthorn leaves.
2. 2. The composition for external use on skin according to claim 1, wherein the extract of sea buckthorn leaves is 0.01 to 95.0% by mass.
Citation Information
Patent Citations
Cosmetic, cosmetic for whole body, and packs containing vitamin k, etc., as active ingredient and used for improving dark spot, dark area, slack under eye, purpura, bruise caused by blow, purpura after laser therapy, etc., and method for producing the same
JP2004051627A
Cosmetic
JP2018043971A