Tube for long life pump

Abstract

To provide a tube structure for a peristaltic pump that maintains ±10% flow rate stability over a long period, resulting in consistent fluid dispensing and / or administration over a long life.SOLUTION: Systems and methods are disclosed that include providing a tube structure comprising at least one layer formed from a thermoplastic vulcanizate (TPV). The tube structure is suitable for use in pump applications that are subject to cyclic loading and unloading.SELECTED DRAWING: Figure 3

Description

Summary of the Invention [Problem to be solved by the invention]

[0001] Peristaltic pumps are used for dispensing and transferring biopharmaceutical fluids, dispensing and transferring chemical fluids, and medical They are used in a variety of fluid transfer industries, including pharmaceutical fluid dispensing, dosing, and transfer applications. These applications often require consistent and predictable dosing or dispensing and / or pumping. However, fluid dispensing using a peristaltic pump requires long service life. The cyclic loading and unloading of pump tubing is very severe. This can result in dimensional changes, fatigue, breakage, and ultimate failure of the tube. These industries continue to demand improvements in pump tubing technology. [Brief explanation of the drawings]

[0002] In order to achieve and more fully understand the features and advantages of the embodiments, reference is made to the accompanying drawings. A more particular description may be had by reference to the illustrated embodiments thereof. While the drawings illustrate only some embodiments, other equally valid embodiments may also be used. It should not be considered limiting in scope, as there may be embodiments.

[0003] [Figure 1] FIG. 1 is a cross-sectional view of a tube structure according to one embodiment of the present disclosure. [Figure 2] FIG. 2 is a cross-sectional view of a multi-layer tubing structure according to one embodiment of the present disclosure. [Figure 3] FIG. 3 is a cross-sectional view of a portion of a fluid pump according to one embodiment of the present disclosure. [Figure 4] FIG. 4 is a flow diagram of a method for operating a fluid pump according to one embodiment of the present disclosure. [Figure 5] FIG. 5 is a graph illustrating comparative fluid flow rate data between a conventional tubing design and an exemplary embodiment of the tubing design. [Figure 6] FIG. 6 is a graph of comparative compression set data between a conventional tube construction and an exemplary embodiment of the tube construction. [Figure 7] FIG. 7 is a graph illustrating comparative normal rebound data between a conventional tube design and an exemplary embodiment of a tube design. [Figure 8] FIG. 8 is a graph illustrating comparative data between a conventional tube design and an exemplary embodiment of a tube design. [Figure 9] FIG. 9 is a graph illustrating comparative data between a conventional tube design and an exemplary embodiment of a tube design.

[0004] The use of the same reference numbers in different drawings indicates similar or identical items. DETAILED DESCRIPTION OF THE INVENTION

[0005] FIG. 1 shows a cross-sectional view of a tube structure 100 according to an embodiment of the present disclosure. The structure 100 generally has an inner diameter (ID) and an outer diameter (OD) through which fluid may be conveyed, pumped, or transferred. The tube structure 100 may be used for transporting biological, chemical, medical, or other fluids that require fluid transfer. The tubing structure 100 may be suitable for consistent fluid dispensing and / or other applications. Suitable for applications requiring long tubing life, long fluid pump life, or long fluid delivery The tube structure 100 may also be highly elastic, and the tube structure 100 and / or or while providing consistent fluid dispensing and / or administration for extended fluid pump life; The tubing structure 100 is suitable for use in applications such as peristaltic pumps where it is subjected to cyclic loading and unloading. It may be preferable to do so.

[0006] The tube structure 100 may generally comprise at least one layer 102. In an embodiment, at least one layer 102 of the tubular structure 100 is made of a thermoplastic vulcanizate (T In some embodiments, the TPV may be formed from a high temperature, semi-crystalline thermoplastic The rubber component may be formed through dynamic vulcanization during melt mixing with the other rubber component. At least one layer 102 of the tube structure 100 is made of a cross-linked rubber and a thermoplastic resin. In some embodiments, the crosslinked rubber may be a synthetic rubber. In some embodiments, the crosslinked rubber is ethylene propylene diene monomer (EPDM). In some embodiments, the thermoplastic resin may include polypropylene. In some embodiments, at least one layer 102 of the tubular structure 100 is made of an extruded material. The tube structure 100 may be formed.

[0007] In some embodiments, the tube structure 100 has a beneficial Shore A durometer In some embodiments, the Shore A hardness may be at least 25A. In some embodiments, the Shore A hardness may be 75A or less. , Shore A hardness: 25A, 30A, 35A, 40A, 45A, 50A, 55A, 65A , or 75A.

[0008] The tube structure 100 is generally made of a material that makes the tube structure 100 highly resilient and durable. and to be resistant to dimensional change, fatigue, fracture, and failure over time. Improved and extended performance over conventional tube structures when subjected to cyclic loading and unloading In some embodiments, the chu The probe structure 100 is defined as the change in flow rate (±) over a given time or over time. In some embodiments, the fluid flow stability may be a predetermined over a period of time or over a long period of time, the flow rate of the tube structure 100 may be ±15% or less, ±14% or less of the original flow rate of the tube structure 100 Bottom, ±13% or less, ±12% or less, ±11% or less, ±10% or less, ±9% or less, ±8% or less In some embodiments, the range may be ±7% or less, ±6% or less, or ±5% or less. A certain period of time or a long period of time means at least 250 hours, at least 300 hours, at least 3 50 hours, at least 400 hours, at least 450 hours, at least 500 hours, at least At least 550 hours, at least 600 hours, at least 750 hours, at least 1000 hours hours, at least 1500 hours, at least 2500 hours, at least 5000 hours, or may be at least 10,000 hours.

[0009] In some embodiments, the tube structure 100 may have beneficial compression set properties. Compression set occurs when a material is compressed at a specific temperature for a specific time. In some embodiments, the compression set is 26% or more. Lower, 25% or less, 24% or less, 23% or less, 22% or less, 21% or less, 20% or less, 19 % or less, 18% or less, 17% or less, 16% or less, or 15% or less. In embodiments, the compression set is at least 15 hours, at least 20 hours, at least for at least 21 hours, at least 22 hours, at least 23 hours, or at least 24 hours In some embodiments, the compression set is at least 150°F. degrees, at least 151 degrees Fahrenheit, at least 152 degrees Fahrenheit, at least 153 degrees Fahrenheit, at least At least 154°F, at least 155°F, at least 156°F, at least 157°F 157°C, at least 158°F, at least 159°F, at least 160°F degrees, at least 170°F, at least 175°F, or at least 180°F In a particular embodiment, the tube construction has a Shore A hardness of 55A. 100 may have a compression set of 23% or less. A tube structure 100 having a Shore A hardness may have a compression set of 18% or less.

[0010] In some embodiments, the tube structure 100 may be highly elastic, and AS Beneficial vertical rebound from the Bayshore rebound test based on TM D2632-15 In some embodiments, the normal rebound may be at least 48%, at least 49% %, at least 50%, at least 51%, at least 52%, at least 53%, at least In certain embodiments, the Shore A is at least 55A. A tube structure 100 having a hardness of A may have a normal rebound of at least 55%. In certain embodiments, a tube structure 100 having a Shore A hardness of 65A has a hardness of at least 5 It may have a vertical rebound of 1%.

[0011] In some embodiments, the tube structure 100 may have a beneficial crosslink density. In some embodiments, the crosslink density is at least 0.005×10 -3 mol / cm 3 , few At most 0.010 x 10 -3 mol / cm 3, at least 0.015 x 10 -3 mol / cm 3 , at least 0.020 x 10 -3 mol / cm 3 , at least 0.025 x 10 -3 mol / cm 3 , at least 0.05 x 10 -3 mol / cm 3 , at least 0.1 0×10 -3 mol / cm 3 , at least 0.25 x 10 -3 mol / cm 3 , at least Also 0.5 x 10 -3 mol / cm 3 , at least 0.75 x 10 -3 mol / cm 3 , small At least 1 x 10 -3 mol / cm 3 , at least 2 × 10 -3 mol / cm 3 , less Tomo3×10 -3 mol / cm 3 , at least 4 × 10 -3 mol / cm 3 ,at least 5×10 -3 mol / cm 3 , at least 6 × 10 -3 mol / cm 3 , at least 7× 10 -3 mol / cm 3 , at least 8 x 10 -3 mol / cm 3 , at least 9 x 10 -3 mol / cm 3 , or at least 10 × 10 -3 mol / cm 3で It's possible. How many? In some embodiments, the crosslink density is 15×10 -3 mol / cm 3 Below, 14 x 10 -3 mo l / cm 3 Below, 13 x 10 -3 mol / cm 3 Below, 12 x 10 -3 mol / cm 3 Below Bottom, 11×10 -3 mol / cm 3 Below, 10 x 10 -3 mol / cm 3 Below, 9 x 10 -3 mol / cm 3 Below, 8 x 10 -3 mol / cm 3 Below, 7 x 10 -3 mol / cm 3 Below, 6 x 10 -3 mol / cm 3 or less, or 5 x 10 -3 mol / cm 3 is as follows: Furthermore, the crosslink density can be between any of these minimum and maximum values, e.g., At least 0.005 x 10 -3 mol / cm 3 From 15 x 10 -3 mol / cm 3 below, or at least 5 x 10 -3 mol / cm 3 From 10 x 10 -3 mol / cm 3 Below It will be understood that this is a good thing.

[0012] In some embodiments, the tube structure 100 may have a beneficial tan δ. In embodiments, tan δ may be 0.12 or less, or 0.11 or less, or 0.10 or less. In some embodiments, tan δ is measured at about 23 degrees Celsius and a frequency of about 10 Hertz (Hz). Measured by number, it may be 0.12 or less, 0.11 or less, or 0.10 or less.

[0013] In some embodiments, the tube structure 100 may have any of these beneficial properties. In some embodiments, the tube structure 100 may comprise any beneficial combination of: may have beneficial Shore A hardness, flow stability, compression set, normal rebound, crosslink density, and / or may comprise a combination of tan δ values. For example, in some embodiments, The structure 100 may have a diameter of at least 20A and no more than 90A, or at least 40A and no more than 70A. Even better Shore A hardness, less than ±10% flow stability over a period of at least 500 hours Qualitative, no more than 26% compression for at least 20 hours at a temperature of at least 150°F Permanent set, normal rebound at least 50%, at least 0.005 x 10 -3 mol / c m 3 From 15 x 10 -3 mol / cm 3 and / or a crosslink density of about 23 degrees Celsius and about It may have a tan δ of less than or equal to 0.10 measured at a frequency of 10 hertz (Hz).

[0014] The tube structure 100 may have dimensions that make the tube structure 100 suitable for a particular application. In some embodiments, the tube structure 100 may have a thickness of at least 0.0625 in. inches, at least 0.125 inches, at least 0.25 inches, at least 0.375 inches In some embodiments, the inner diameter may be 0.50 inches, or at least 0.50 inches. The tube structure 100 may be at least 0.125 inches, at least 0.25 inches, or at least All have an outer diameter of 0.50 inches, at least 0.75 inches, or at least 1.0 inches. For example, in certain embodiments, the tube structure 100 may have an internal diameter of 0.255 inches. diameter and an outer diameter of 0.385 inches. The tube structure 100 may have dimensions suitable for any particular application.

[0015] FIG. 2 is a cross-sectional view of a multi-layer tubular structure 200 according to one embodiment of the present disclosure. One layer is formed from a thermoplastic vulcanizate (TPV) containing crosslinked rubber and a thermoplastic resin. We also review the above-referenced performance and In some embodiments, the multi-layer tubular structure 200 may comprise multiple layers 102, 202. In some embodiments, the multi-layer tube structure 2 00 is at least one of the tube structures 100 formed from thermoplastic vulcanizate (TPV). In some embodiments, the multi-layered chip may comprise a first layer 102 and one or more additional layers 202. The tube structure 200 may include one or more additional inner layers 202a, one or more additional outer layers 202b, or In some embodiments, at least one layer 102 may comprise a , may be the innermost layer of the multi-layer tubular structure 200. In some embodiments, at least one The layer 102 may be the outermost layer of the multi-layer tubular structure 200 .

[0016] In some embodiments, one or more additional layers 202 may be formed from a polymeric material. In some embodiments, one or more additional layers 202 may be formed from a thermoplastic material. In some embodiments, one or more additional layers 202 may be formed from a rubber material. In some embodiments, one or more additional layers 202 may be connected to the layer 102 of the tube structure 100. It may be formed from a substantially similar thermoplastic vulcanizate (TPV). , at least one layer 102 and one or more additional layers 202 of the multi-layer tubular structure 200. may be co-extruded to form the multi-layer tubular structure 200.

[0017] In some embodiments, the multi-layered tubular structure 200 is substantially the same as the tubular structure 100. and may be suitable for substantially similar applications. In the present invention, the multi-layer tube structure 200 has improved flow stability, improved compression set, Improved normal rebound, beneficial crosslink density, beneficial tan δ, or any combination thereof The tube structure 100 may have substantially similar properties and / or performance characteristics, resulting in:

[0018] The multi-layer tubing structure 200 has various configurations that make the multi-layer tubing structure 200 suitable for particular applications. In some embodiments, the multi-layer tubular structure 200 may further comprise dimensions such as: At least 0.0625 inches, at least 0.125 inches, at least 0.25 inches, at least Some may have an inside diameter of at least 0.375 inches, or at least 0.50 inches. In an embodiment, the multi-layer tubular structure 200 has a thickness of at least 0.125 inches, at least 0 0.25 inches, at least 0.50 inches, at least 0.75 inches, or at least For example, in certain embodiments, the multi-layer tubing structure 200 may have an outer diameter of 1.0 inch. may have an inner diameter of 0.255 inches and an outer diameter of 0.385 inches. In other embodiments, the multi-layer tubular structure 200 may be provided with dimensions suitable for any particular application. That's fine.

[0019] FIG. 3 illustrates a cross-sectional view of a portion of a fluid pump 300 according to an embodiment of the present disclosure. In some embodiments, the fluid pump 300 may comprise a peristaltic pump. In some embodiments, the fluid pump 300 may comprise a tubing structure 100. The pump 300 may comprise a multi-layer tubing structure 200. Additionally, in some embodiments, The pump 300 is coupled to the rotor and includes the tubing structure 100 or the multi-layer tubing structure 200. The tube structure 100 or the multi-layer tube structure 200 may be provided with a circumferential wall to force fluid therethrough. The device may include one or more rollers 302 configured to apply periodic loading and unloading.

[0020] FIG. 4 illustrates a flow diagram of a method 400 of operating a fluid pump 300, according to one embodiment of the present disclosure. 4 shows a block 402 of a method 400 for performing a chip according to an embodiment disclosed herein. One may begin by providing a fluid pump 300 with tube structures 100, 200. The method 400 begins operation of the fluid pump 300 at an initial fluid flow rate to The method 400 may continue at block 404. The method 400 may continue at block 404 by increasing the initial fluid flow rate by 10% for a predetermined period of time. Some implementations may continue at block 406 by maintaining the following fluid flow rates: In some embodiments, the predetermined time is at least 250 hours, at least 300 hours, or at least 3 50 hours, at least 400 hours, at least 450 hours, at least 500 hours, at least At least 550 hours, at least 600 hours, at least 750 hours, at least 1000 hours hours, at least 1500 hours, at least 2500 hours, at least 5000 hours, or may be at least 10,000 hours. [Example]

[0021] FIG. 5 shows conventional tube structures (C1 and C2) and an exemplary implementation of tube structure 100. Graphs of comparative fluid flow data for configurations (S1 and S2) are shown. Each of the S2 has an inside diameter (ID) of 0.255 inches and an outside diameter (OD) of 0.385 inches. Comparing C1 and S1, their Shore A hardness is 55 A. Comparing C2 and S2, their Shore A hardness was 65A. C1, C2 The initial flow rate of each of S1, S2, and S3 was recorded (shown as 1.0 on the graph). Figure 1 shows a plot of the original flow rate versus time (hours). Each was pumped at 600 RPM continuously with a back pressure of 10 psi for the indicated extended periods. C1 fell below ±10% flow rate stability for approximately 300 hours, The S1 maintained a flow rate stability of ±10% for at least approximately 900 hours. C2 maintains ±10% flow rate stability for approximately 300% longer than C1. The S2 rapidly falls below ±10% flow stability in about 15 hours, while the S3 rapidly falls below ±10% flow stability in about 600 hours. The results showed that S2 was approximately 4000% longer than C2. The long-term flow stability of S1 and S2 is shown to be ±10%. , maintaining accurate dispensing or administration over a longer period of time compared to C1 and C2; and / or may translate to longer pump life.

[0022] FIG. 6 shows conventional tube structures (C1 and C2) and an exemplary implementation of tube structure 100. A graph of comparative compression set data for the forms (S1 and S2) is shown. , and S2 each have an inner diameter (ID) of 0.255 inches and an outer diameter (OD) of 0.385 inches. D) was composed of a single-layer tube. Comparing C1 and S1, their Shore A hardness The Shore A hardness of C1 was 55A. Comparing C2 and S2, the Shore A hardness of C1 was 65A. Each of C2, S1, and S2 was heated at a temperature of 158 degrees Fahrenheit for a period of approximately 22 hours. The compression force was removed and the compression set value was measured. C1 was 28.98%. The results were: S1 exhibited a compression set of 22.64%, while S2 exhibited a compression set of 22.64%. , S1 undergoes over 6% less compression set compared to C1 and is therefore more elastic. C2 showed a compression set of 26.37%, while S2 showed a compression set of 17.95%. The results showed that S2 had over 8% less compression set compared to C2. This indicates that the material is more susceptible to stress and therefore more elastic.

[0023] FIG. 7 shows conventional tube structures (C1 and C2) and an exemplary implementation of tube structure 100. Graphs of comparative vertical rebound data for configurations (S1 and S2) are shown. C1, C2, S1, and Each of the S2 has an inside diameter (ID) of 0.255 inches and an outside diameter (OD) of 0.385 inches. Comparing C1 and S1, their Shore A hardness is 55 A. Comparing C2 and S2, their Shore A hardness was 65A. C1, C2 , S1, and S2 were measured by Bayshore Vertical Rebound Test (BSRT) in accordance with ASTM D2632-15. The C1 showed a vertical rebound of 56%, while the S1 showed an equivalent vertical rebound of 55%. The results show that S1 has substantially similar vertical repulsion compared to C1. The C2 showed a vertical rebound of 48%, while the S2 showed a vertical rebound of 51%. 2 has 3% better normal rebound and therefore more resistant to rapid deformation compared to C2. This indicates that the

[0024] FIG. 8 shows conventional tube structures (C1 and C2) and an exemplary implementation of tube structure 100. The graph shows the comparative data for the morphologies (S1 and S2). Each consisted of a single-walled tube with a Shore A hardness of 55A. 2 has lower tan δ values ​​at all frequencies compared to C1 and C2, and The storage modulus remained similar. The results show that S1 and S2 have better pump performance (flow stability) compared to C1 and C2. This shows that it contributes to the quality and life of the pump.

[0025] FIG. 9 shows conventional tube structures (C1 and C2) and an exemplary implementation of tube structure 100. The graph shows the comparative data for the morphologies (S1 and S2). Each consisted of a single-walled tube with a Shore A hardness of 65A. 2 has lower tan δ values ​​at all frequencies compared to C1 and C2, and It shows that it has a slightly lower loss modulus and a slightly lower storage modulus at all frequencies. These results show that S1 and S2 have better pump performance ( This shows that it contributes to flow stability and pump life.

[0026] In yet another embodiment, the tubular structure 100, the multi-layered tubular structure 200, and / or The method 300 of operating a fluid pump may include one or more of the following embodiments: .

[0027] Embodiment 1. Comprising at least one layer formed from a thermoplastic vulcanizate (TPV) , Tube structure.

[0028] Embodiment 2. The TPV is melt mixed with the semi-crystalline thermoplastic component at elevated temperatures while the rubber component is being melt mixed. 10. The tubing structure of embodiment 1, formed via dynamic vulcanization.

[0029] Embodiment 3. Any of Embodiments 1-2, wherein the TPV comprises a crosslinked rubber and a thermoplastic resin. 1. The tube structure described in

[0030] Embodiment 4. The tube structure of embodiment 3, wherein the cross-linked rubber is a synthetic rubber.

[0031] Embodiment 5. The crosslinked rubber is ethylene propylene diene monomer (EPDM). The tube structure according to any one of the third and fourth embodiments.

[0032] Embodiment 6. The method of any one of embodiments 3 to 5, wherein the thermoplastic is polypropylene. Tube structure.

[0033] Embodiment 7. An embodiment in which at least one layer is extruded to form a tubular structure. The tube structure according to any one of aspects 1 to 6.

[0034] Embodiment 8. The tube structure is 25A, 30A, 35A, 40A, 45A, 50A, Any one of embodiments 1 to 7, having a Shore A hardness of 55A, 65A, or 75A. The tube structure described.

[0035] Embodiment 9. The tube structure is formed by the tube structure for a predetermined time or for an extended period of time. of flow rate ±15% or less, ±14% or less, ±13% or less, ±12% or less, ±11% or less, ± Fluids with a tolerance of 10% or less, ±9% or less, ±8% or less, ±7% or less, ±6% or less, or ±5% or less 9. A tube structure according to any one of embodiments 1 to 8, which has flow stability.

[0036] Embodiment 10. The predetermined or extended period of time is at least 250 hours, at least 300 hours hours, at least 350 hours, at least 400 hours, at least 450 hours, at least At least 500 hours, at least 550 hours, at least 600 hours, at least 750 hours, At least 1000 hours, at least 1500 hours, at least 2500 hours, at least 10. The tube structure of embodiment 9, having a durability of at least 5,000 hours, or at least 10,000 hours. Construction.

[0037] Embodiment 11. The tube structure is resistant to wear for a predetermined or extended period of at least 500 hours. 11. The tube structure of embodiment 10, having a flow rate stability of ±10% or less.

[0038] Embodiment 12. The tube structure is 26% or less, 25% or less, 24% or less, or 23% or less , 22% or less, 21% or less, 20% or less, 19% or less, 18% or less, 17% or less, 16% 12. The method of claim 1, wherein the compression set is 15% or less. Tube structure.

[0039] Embodiment 13. Compression set is at least 15 hours, at least 20 hours, or less at least 21 hours, at least 22 hours, at least 23 hours, or at least 24 hours 13. The tube structure of embodiment 12, evaluated over a period of time.

[0040] Embodiment 14. Compression set at least 150°F, at least 151°F , at least 152°F, at least 153°F, at least 154°F, at least At least 155°F, at least 156°F, at least 157°F, at least 158°F 158°C, at least 159°F, at least 160°F, at least 170°F 175°F, or at least 180°F. 14. The tube structure according to claim 13.

[0041] Embodiment 15. The tube structure has a Shore A hardness of 55A and a compression set of 23% or less. The tube structure according to any one of embodiments 12 to 14, comprising:

[0042] Embodiment 16. The tube structure has a Shore A hardness of 65A and a compression set of 18% or less. 14. The tube structure according to any one of embodiments 11 to 13, comprising:

[0043] Embodiment 17. The tube structure is at least 50%, at least 51%, at least 52%, at least 53%, at least 54%, or at least 55% of ASTM D Embodiments 1 to 16 are provided with a vertical rebound according to the Bayshore rebound test based on 2632-15. 10. A tube structure according to any one of claims 1 to 9.

[0044] Embodiment 18. The tube structure has a Shore A hardness of 55A and a vertical cross section of at least 55%. 18. The tube structure of embodiment 17, comprising a resilience.

[0045] Embodiment 19. The tube structure has a Shore A hardness of 65A and a vertical cross section of at least 51%. 18. The tube structure of embodiment 17, comprising a resilience.

[0046] Embodiment 20. The tube structure has a pore size of at least 0.005 × 10 mol / cm ; At least 0.010×10-3mol / cm3, at least 0.015×10-3mo l / cm3, at least 0.020×10-3mol / cm3, at least 0.025× 10-3mol / cm3, at least 0.05×10-3mol / cm3, at least 0 0.10×10-3mol / cm3, at least 0.25×10-3mol / cm3, less At least 0.5×10-3mol / cm3, at least 0.75×10-3mol / cm3 , at least 1×10-3mol / cm3, at least 2×10-3mol / cm3, a little at least 3×10-3mol / cm3, at least 4×10-3mol / cm3, at least At least 5×10-3mol / cm3, at least 6×10-3mol / cm3, at least 7×10-3mol / cm3, at least 8×10-3mol / cm3, at least 9× 10-3mol / cm3, or a crosslink density of at least 10 x 10-3mol / cm3 The tube structure according to any one of embodiments 1 to 19.

[0047] Embodiment 21. The tube structure has a viscosity of 15 × 10-3 mol / cm3 or less, 14 × 10- 3mol / cm3 or less, 13×10-3mol / cm3 or less, 12×10-3mol / c m3 or less, 11×10-3 mol / cm3 or less, 10×10-3 mol / cm3 or less, 9 ×10-3mol / cm3 or less, 8×10-3mol / cm3 or less, 7×10-3mol / cm3 or less, 6×10-3mol / cm3 or less, or 5×10-3mol / cm3 or less 21. The tube structure of any one of embodiments 1 to 20, having a crosslink density of

[0048] Embodiment 22. The tube structure has a thickness of 0.12 or less, 0.11 or less, or 0.10 or less. 22. A tube structure according to any one of embodiments 1 to 21, comprising a tan δ.

[0049] Embodiment 23. The tube structure is heated to about 23 degrees Celsius and a frequency of about 10 hertz (Hz). and having a tan δ of 0.12 or less, 0.11 or less, or 0.10 or less, as measured in embodiments 23. The tube structure according to any one of aspects 1 to 22.

[0050] Embodiment 24. The tube structure has a Shore A hardness of at least 50A to 70A or less; Flow stability of ±10% or less over a period of at least 500 hours, at least 15°F Compression set of 26% or less for at least 20 hours at 0°C, at least 5 0% vertical repulsion, at least 0.005×10-3mol / cm3 to 15×10-3m a crosslink density of less than 1000 mol / cm3 and / or a temperature of about 23 degrees Celsius and a frequency of about 10 Hertz (Hz) 24. Any one of embodiments 1 to 23, having a tan δ of 0.10 or less, as measured by the tangent Tube structure.

[0051] Embodiment 25. The tube structure has a Shore A hardness of 55A and a temperature of at least 500 hours. ±10% flow stability over a fixed or extended period at temperatures of at least 150°F Compression set of 23% or less and flexural strength of at least 55% for at least 20 hours 25. The tube structure of embodiment 24, comprising a direct rebound.

[0052] Embodiment 26. The tube structure has a Shore A hardness of 65A and a durability of at least 500 hours. ±10% flow stability over a fixed or extended period at temperatures of at least 150°F Compression set of 18% or less and flexural strength of at least 51% for at least 20 hours 25. The tube structure of embodiment 24, comprising a direct rebound.

[0053] Embodiment 27. The tube structure is a multi-layer tube structure with one or more additional layers. 27. A tube structure according to any one of embodiments 1 to 26.

[0054] Embodiment 28. One or more additional layers may be one or more inner layers, one or more outer layers, or both. 28. The tube structure of embodiment 27, comprising a combination of:

[0055] Embodiment 29. At least one layer formed from a thermoplastic vulcanizate (TPV) is multi-layered. 29. The tube structure according to any one of embodiments 27 to 28, which is the innermost layer of a multi-layer tube structure. Construction.

[0056] Embodiment 30. At least one layer formed from a thermoplastic vulcanizate (TPV) is multi-layered. The tube structure according to any one of embodiments 27 to 28, which is the outermost layer of a multi-layer tube structure. Structure.

[0057] Embodiment 31. The method of embodiment 2, wherein at least one additional layer is formed from a polymeric material. The tube structure according to any one of 7 to 30.

[0058] Embodiment 32. The method of embodiment 2, wherein at least one additional layer is formed from a thermoplastic material. The tube structure according to any one of 7 to 30.

[0059] Embodiment 33. At least one additional layer is formed from a rubber material, as in embodiments 27 to 29. 30. A tube structure according to any one of claims 1 to 30.

[0060] Embodiment 34. At least one additional layer is formed from a thermoplastic vulcanizate (TPV). 31. A tube structure according to any one of embodiments 27 to 30.

[0061] Embodiment 35. At least one layer and one or more additional layers are coextruded to form a multilayer tube. 35. The tube structure according to any one of embodiments 27 to 34, forming a tube structure.

[0062] Embodiment 36: A tube structure according to any one of embodiments 1 to 35, and a tube structure to subject the tube structure to cyclic loading and unloading in order to force a fluid through the tube. a rotor comprising one or more rollers configured.

[0063] Embodiment 37. A fluid pump as described in embodiment 36, wherein the pump comprises a peristaltic pump.

[0064] Embodiment 38: A fluid having a tube structure according to any one of embodiments 1 to 35. Preparing the pump and starting operation of the fluid pump at an initial fluid flow rate and and maintaining a fluid flow rate of no more than ±10% of the initial fluid flow rate over the period of time. How to operate the pump.

[0065] Embodiment 39. A fluid pump is provided in a tube structure to push fluid through the tube structure. A roller having one or more rollers configured to apply cyclic loading and unloading to a roller structure. 39. The method of embodiment 38, comprising a peristaltic pump having a motor.

[0066] Embodiment 40. The predetermined time is at least 250 hours, at least 300 hours, or at least At least 350 hours, at least 400 hours, at least 450 hours, at least 500 hours At least 550 hours, at least 600 hours, at least 750 hours, at least 1000 hours, at least 1500 hours, at least 2500 hours, at least 5000 39. Any one of embodiments 38-39, wherein the temperature is at least 10,000 hours. How to do it.

[0067] This written description is provided to disclose embodiments thereof, including the best mode, and is also to enable any person skilled in the art to understand the invention. Examples are used to make and use the invention. The scope of the present invention is defined by the claims, and may include other examples that occur to those skilled in the art. Other embodiments have structural elements that do not differ from the literal language of the claims. or equivalent structural elements that do not substantially differ from the literal words of the claims. If the invention includes elements, it is intended to be within the scope of the claims.

[0068] Not all of the activities described above are required in the general description or examples. Some specific activities may not be required, and one or more activities in addition to those described may be required. Note that further actions may be performed. Furthermore, the order in which the actions are listed is not necessarily Nor is the order in which they are performed.

[0069] In the foregoing specification, concepts have been described with reference to specific embodiments. Those skilled in the art will appreciate that various modifications may be made without departing from the scope of the invention as set forth in the following claims. It is understood that various modifications and variations may be made to the present invention. All such modifications are to be considered in an illustrative rather than a restrictive sense. are intended to be included within the scope of the present invention.

[0070] As used herein, "comprises" and "comprising" "," includes,"," including,"," has,"," has The term "(ing)" or any other variation thereof is intended to cover a non-exclusive inclusion. For example, a process, method, article, or apparatus that includes a list of features is not necessarily a It is not limited to only those features and is not expressly listed or includes any such process. Further, unless expressly stated to the contrary, and "or" refers to an inclusive or and not an exclusive or. For example, Condition A or B is satisfied by one of the following: A is true (or exists) ), B is false (or does not exist), A is false (or does not exist) and B is true ( A and B are both true (or exist).

[0071] Also, the use of "a" or "an" refers to any element or elements described herein. This is done merely for convenience and to provide a general idea of ​​the scope of the invention. This statement is to be read to include one or at least one. and the singular also refers to the plural unless it is clear that it is meant otherwise. include.

[0072] Benefits, other advantages, and solutions to problems have been described above with regard to specific embodiments. However, benefits, advantages, solutions to problems, and any benefits, advantages, or solutions that Any feature that may render the invention less or more prominent may be added to any or all of the claims. They should not be construed as necessary or essential features.

[0073] After reading this specification, it will become apparent to those skilled in the art that certain features may be presented in separate embodiments for clarity. and are provided in combination in a single embodiment. Conversely, for the sake of brevity, the invention may be described in the context of a single embodiment. The various features described may be provided separately or in any subcombination. References to values ​​stated in ranges include each and every value within that range.

Claims

1. A tube structure comprising at least one layer formed from a thermoplastic vulcanizate (TPV). Construction.

2. The TPV is melt mixed with the semi-crystalline thermoplastic component at elevated temperatures during dynamic vulcanization of the rubber component. The tubing structure of claim 1 formed via

3. The TPV according to any one of claims 1 to 2, wherein the TPV comprises a crosslinked rubber and a thermoplastic resin. Tube structure.

4. 4. The tube structure of claim 3, wherein the cross-linked rubber is a synthetic rubber.

5. 4. The method according to claim 3, wherein the crosslinked rubber is ethylene propylene diene monomer (EPDM). The tube structure described.

6. 4. The tubing structure of claim 3, wherein said thermoplastic is polypropylene.

7. 7. A method according to claim 1, wherein the tube structure has a Shore A hardness of 25A. The tube structure described.

8. The tube structure is adapted to retain the original flow of the tube structure for a predetermined or extended period of time.

8. The tube of claim 1, wherein the tube has a fluid flow rate stability of ±15% or less. Tube structure.

9. The tube structure has at least 50% of the base material conforming to ASTM D2632-15. The tube according to any one of claims 1 to 8, which has a vertical rebound according to the Ishore rebound test. Block structure.

10. The tube structure has a thickness of at least 0.005×10 －３ mol / cm ３ Cutlet 15 x 1 0 －３ mol / cm ３ The crosslinked polymer of any one of claims 1 to 9, having a crosslink density of: Tube structure.

11. The tube structure has a Shore A hardness of at least 50A to no more than 70A, Flow stability of ±10% or less over a 500 hour period, at a temperature of at least 150°F Compression set of 26% or less for at least 20 hours, perpendicular Rebound, at least 0.005 x 10 －３ mol / cm ３ From 15 x 10 －３ mol / cm ３ or a crosslink density of 0.5 or less as measured at about 23 degrees Celsius and a frequency of about 10 Hertz (Hz).

11. A tube structure according to any one of claims 1 to 10, having a tan δ of 10 or less.

12. 10. The method of claim 1, wherein the tubing is a multi-layer tubing comprising one or more additional layers.

12. A tube structure according to any one of claims 1 to 11.

13. The at least one additional layer is made of a polymeric material, a thermoplastic material, a rubber material, or a thermoplastic material.

13. The tubing structure of claim 12 formed from a thermoplastic vulcanizate (TPV).

14. at least one layer formed from a thermoplastic vulcanizate (TPV); A periodic load is applied to the tubing structure to force a fluid through the tubing structure. a rotor comprising one or more rollers configured to apply a load and an unload; A fluid pump comprising:

15. A fluid pump is provided that includes a tube structure according to any one of claims 1 to 13. And, commencing operation of the fluid pump at an initial fluid flow rate; maintaining a fluid flow rate of no more than ±10% of the initial fluid flow rate for a predetermined period of time; 、 10. A method of operating a fluid pump, comprising:

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