Skin Brightening Composition

Abstract

The present invention relates to a personal care composition that lightens the skin. More particularly, the present invention relates to a topical composition that is effective against hyperpigmentation. This is accomplished by including in the topical composition: (i) a retinoic acid precursor; (ii) a carboxylic acid functionalized heteroaromatic compound selected from one or more of nicotinic acid, picolinic acid, nicotinate, niacinamide, and picolinamide; (iii) an alkylresorcinol; (iv) inulin; and (v) a cosmetically acceptable vehicle.

Description

[Technical field]

[0001] The present invention relates to personal care compositions that lighten the skin. More particularly, the present invention relates to topical compositions that are effective against hyperpigmentation, especially hyperpigmentation caused by exposure to the sun. [Background technology]

[0002] Most people consider the appearance of their skin, especially the appearance of the skin on their face, as one of the important indicators of their own beauty and health. Thus, having a light, blemish-free, even skin tone is desired by many people. The degree and evenness of skin pigmentation is affected by factors such as age, hormonal changes, acne development, and exposure to sunlight and environmental pollution. These can lead to age spots or freckles, hyperpigmentation in certain localized areas of the skin, and even dark circles under the eyes. Many people believe that certain lifestyle factors, such as hydration (amount of water consumed), type of diet, and amount and quality of sleep, also affect the appearance of the skin, including dark circles under the eyes. People are aware that changes such as living a healthier lifestyle can take a long time to even out the appearance of the skin, so they turn to cosmetics that provide a temporary solution to skin blemishes. They also want products to reduce the darkening of the skin caused by exposure to sunlight. To meet this need, many attempts have been made to develop products that reduce pigment production in melanocytes.

[0003] The inventors have been working in this field for a long time and have filed several patent applications and produced various cosmetic products on the market. In the present invention, they were specifically looking for a highly effective solution to this problem, which could also be used as a general cosmetic product to provide a uniform and light skin tone, especially on exposed skin surfaces.

[0004] They want to ensure that the product they develop is equal to or better than the most effective products on the market. After screening a large number of actives, they found that one or more of the skin care actives known for providing an even skin tone, such as alkylresorcinols or carboxylic acid functionalized heteroaromatic compounds, or retinoic acid compounds known for their anti-aging benefits, when combined with inulin, provide enhanced skin brightness and even skin tone. To the best of the inventors' knowledge, no combination of actives that provide such benefits has been known so far. Furthermore, it is generally desirable for conventional skin care actives known for this benefit, such as alkylresorcinols or carboxylic acid functionalized heteroaromatic compounds or retinoic acid compounds, to be included in lower amounts, which not only reduces costs but also ensures better compatibility with other ingredients in the formulation, thereby resulting in better formulation stability. The inventors were looking for a solution to identify additives that exhibit synergy with the above conventional skin care actives, allowing the additives to be included at very low concentrations, thereby providing all of the above benefits. Summary of the Invention [Problem to be solved by the invention]

[0005] It is therefore an object of the present invention to provide a solution to the problem of hyperpigmentation and uneven skin appearance, thereby resulting in a brighter skin appearance.

[0006] Another object of the present invention is to provide such a solution that allows the inclusion of lower amounts of skin care actives, thereby ensuring better formulation stability. [Means for solving the problem]

[0007] A first aspect of the present invention relates to a personal care composition comprising: (i) a retinoic acid precursor selected from one or more of retinyl esters, retinol, retinal, and retinoic acid; (ii) a carboxylic acid functionalized heteroaromatic compound selected from one or more of nicotinic acid, picolinic acid, nicotinate, niacinamide, and picolinamide; and, (iii) an alkylresorcinol; (iv) inulin; and, (v) a cosmetically acceptable vehicle.

[0008] Another aspect of the invention relates to a method of providing lightness to the skin, the method comprising the step of applying to the skin a composition of the first aspect. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0009] These and other aspects, features and advantages will become apparent to those skilled in the art upon reading the following detailed description and the appended claims. For the avoidance of doubt, any feature of one aspect of the present invention may be utilized in any other aspect of the present invention. The word "comprising" is intended to mean "including" but not necessarily "consisting of" or "composed of". That is, the listed steps or options need not be exhaustive. It should be noted that the examples set forth in the following description are intended to clarify the invention and are not intended to limit the invention to those examples themselves. Similarly, all percentages are weight / weight percents unless otherwise indicated. Except in the examples and comparative examples or where otherwise expressly indicated, all numerical values ​​given for amounts of materials or reaction conditions, physical properties and / or uses of materials in the present specification and claims should be understood as being modified by the word "about". Numerical ranges expressed in the format "from x to y" are understood to include x and y. When multiple preferred ranges for a particular feature are described in the format "from x to y," it is understood that all ranges combining the different endpoints are also contemplated.

[0010] The compositions of the present invention are intended for personal care or cosmetic use and may also be referred to as personal care or cosmetic compositions. As used herein, "personal care compositions" are intended to include compositions for topical application, i.e., compositions for the external surface of human skin. Such compositions may be classified as leave-on or rinse-off and include any product applied to the human body for improving appearance, cleansing, odor control or general aesthetics. The compositions are preferably leave-on compositions. The compositions of the present invention may be in the form of a liquid, lotion, cream, foam, stick, serum, essence or gel. Preferred compositions include leave-on gels, lotions, serums or creams, preferably in the form of a serum or cream.

[0011] "Skin" as used herein is intended to include the skin of the face and body (e.g., the neck, chest, back, arms, armpits, hands, legs and scalp), particularly those exposed areas thereof.

[0012] The present invention provides personal care compositions comprising: (i) a retinoic acid precursor; (ii) a carboxylic acid functionalized heteroaromatic compound selected from one or more of nicotinic acid, picolinic acid, nicotinate, niacinamide, and picolinamide; (iii) an alkylresorcinol; (iv) inulin; and (v) a cosmetically acceptable vehicle.

[0013] Retinoic acid precursors according to the present invention may be selected from one or more of retinyl esters, retinol, retinal and retinoic acid, preferably retinal or retinyl esters. Examples of retinyl esters suitable for use in the present invention include, but are not limited to, retinyl palmitate, retinyl formate, retinyl acetate, retinyl propionate, retinyl butyrate, retinyl valerate, retinyl isovalerate, retinyl hexanoate, retinyl heptanoate, retinyl octanoate, retinyl nonanoate, retinyl decanoate, retinyl undecanoate, retinyl taurate, retinyl tridecanoate, retinyl myristate, retinyl pentadecanoate, retinyl heptadecanoate, retinyl stearate, retinyl isostearate, retinyl nonadecanoate, retinyl arachidonate, retinyl behenate, retinyl linoleate, and retinyl oleate. Preferred esters for use in the present invention are selected from retinyl palmitate, retinyl acetate, retinyl propionate and mixtures thereof. Also preferred are retinyl linoleate and retinyl oleate. The most preferred retinoic acid precursor is retinyl propionate. The retinoic acid precursor is used in the present composition in an amount of 0.001-10%, preferably 0.01-1%, most preferably 0.01-0.5%.

[0014] The composition of the present invention may include a carboxylic acid functionalized heteroaromatic compound. The carboxylic acid functionalized heteroaromatic compound may be selected from one or more of nicotinic acid, picolinic acid, nicotinate, niacinamide and picolinamide. It is preferably one or both of niacinamide and picolinamide, and most preferably niacinamide. The carboxylic acid functionalized heteroaromatic compound is typically included in an amount of 0.01-10% by weight of the cosmetic composition, preferably 0.05-7% by weight, more preferably 0.1-5% by weight, including all ranges contained therein.

[0015] Resorcinol is a dihydroxyphenolic compound (i.e., 1,3-dihydroxybenzene) characterized by having alcohol groups (-OH) at the 1- and 3-positions. The chemical structure of resorcinol can be modified to obtain substituted resorcinols characterized by having at least one substituent at the 2-, 4-, 5-, or 6-positions. The resorcinol preferably contains at least one substituent containing 2 to 11 carbon atoms (preferably 2 to 8 carbon atoms, most preferably 2 to 6 carbon atoms). Particularly preferably, the at least one substituent contains an alkyl group, and more preferably an unsaturated alkyl group. The resorcinol compound contained in the cosmetic composition of the present invention is an oil-soluble alkylresorcinol.

[0016] Preferably, the resorcinol of the cosmetic composition is substituted with an alkyl group only at the 4-position. That is, the resorcinol is an alkylresorcinol, more preferably a 4-substituted alkylresorcinol. Illustrative non-limiting examples of 4-substituted alkylresorcinols include 4-ethylresorcinol, 4-hexylresorcinol, 4-phenylethylresorcinol, 4-cyclopentylresorcinol, 4-cyclohexylresorcinol, 4-octylresorcinol, and mixtures thereof. More preferred alkylresorcinols for use in the present invention are one or both of 4-ethylresorcinol and 4-hexylresorcinol; most preferred is 4-hexylresorcinol. The composition comprises 0.001-10%, preferably 0.01-5%, most preferably 0.01-1% by weight of the cosmetic composition of an alkylresorcinol, including all ranges therein.

[0017] Inulin is a polysaccharide composed of 2-60 fructose units with one terminal glucose molecule. Inulin is a generic term that encompasses all β-(2,1) fructans. The general structure of inulin is depicted below:

[0018] [ka]

[0019] Inulin occurs naturally in many common plants such as chicory, Jerusalem artichoke, onion, garlic, barley, rye and wheat. Inulin is abundant in chicory and is commonly extracted from chicory for commercial production. Inulin is a well-known prebiotic and has antibacterial and anticancer activity. Inulin is recognized in most countries as a food ingredient that can be used without restrictions in food formulations. Inulin has been present in skin care compositions as a humectant and moisturizing agent. Inulin has the CAS number 9005-80-5. Its IUPAC name is fructosan. Inulin is preferably present in the compositions of the present invention at 0.01-10% by weight of the composition, more preferably 0.01-5% by weight, and most preferably 0.01-1% by weight. For use in the present invention, inulin was obtained from Sigma Aldrich, USA.

[0020] The composition preferably comprises an oil having a Hansen total solubility parameter (δt) value in the range of 16.5 to 22. Preferred oils may be selected from one or more of isopropyl myristate, isopropyl palmitate, caprylic / capric triglyceride and benzyl alcohol. These oils are preferably comprised in an amount of 8 to 25% by weight of the composition.

[0021] The composition of the present invention preferably contains an emulsifying polymer, which is preferably a swellable polymer powder made of pure acrylic acid monomers or a mixture of acrylic acid monomers and methacrylic acid monomers, and preferably an acrylate / C 10-30The polymer may be a polymer having the chemical name of alkyl acrylate crosspolymer, carbomer, or a mixture thereof. In one embodiment, the polymer is a crosslinked homopolymer or a non-crosslinked homopolymer. In another embodiment, the polymer is a crosslinked copolymer or a non-crosslinked copolymer. The emulsifying polymer is multifunctional and can emulsify the composition, stabilize the composition, and / or build the viscosity of the composition. It is within the scope of the present invention to use the polymeric emulsifier alone or in combination with other additional polymeric emulsifiers. Exemplary non-limiting acrylate / C for use in the cosmetic composition of the present invention are: 10-30 Alkyl acrylate crosspolymer is PEMULEN TM TR-1, PEMULEN TM TR-2, PEMULEN TM Carbomers are commercially available under the trade names EZ-4U, CARBOPOL® Ultrez 20, CARBOPOL® Ultrez 21, CARBOPOL® 1382, and CARBOPOL® ETD 2020 from the supplier The Lubrizol Corporation. Preferred carbomers for use in the compositions of the present invention include CARBOPOL® Ultrez 10 and CARBOPOL® 980, both of which are commercially available from The Lubrizol Corporation. The emulsifying polymer is present in the cosmetic composition in an amount of 0.01-5% by weight of the cosmetic composition, preferably 0.02-4% by weight, and more preferably 0.03-3% by weight. More preferably, the polymer is present in the cosmetic composition in an amount of 0.04-2% by weight, and most preferably 0.05-1% by weight, of the cosmetic composition, including all ranges therein.

[0022] The compositions of the present invention may further comprise one or more of a sunscreen, a light stabilizer, a skin brightening agent, a wrinkle reducing agent, and a colorant.

[0023] The composition may further comprise an organic sunscreen selected from one or both of UVA and UVB sunscreens. Sunscreens include materials commonly employed to block ultraviolet light. Exemplary compounds are derivatives of PABA, cinnamate and salicylate. For example, avobenzophenone (Parsol 1789®), octyl methoxycinnamate and 2-hydroxy-4-methoxybenzophenone (also known as oxybenzone) can be used. Octyl methoxycinnamate and 2-hydroxy-4-methoxybenzophenone are commercially available under the trade names Parsol MCX and Benzophenone-3, respectively. The exact amount of sunscreen used in the composition can vary depending on the degree of protection desired from the sun's ultraviolet rays. Additives that reflect or scatter the sun's rays can also be used. These additives include oxides such as zinc oxide and titanium dioxide.

[0024] The compositions of the present invention comprise a cosmetically acceptable vehicle, which may act as a diluent, dispersant and / or carrier for the active agents used in the composition to facilitate their distribution when the composition is applied to the skin. The cosmetically acceptable vehicles suitable for use in the present invention may be aqueous, anhydrous or emulsion; preferably, they are aqueous or emulsion, where the emulsion is a water-in-oil emulsion or an oil-in-water emulsion, the latter being most preferred. Water, when present, usually constitutes the balance of the composition. Preferably, water is present at a concentration of 5-99% by weight of the composition, more preferably at a concentration of 20-80% by weight, even more preferably at a concentration of 40-80% by weight.

[0025] The composition of the present invention can be delivered in the form of a serum, cream, lotion or gel, preferably in the form of a cream. A preferred form of the solid form of the composition is a cream, more preferably a cream having a vanishing cream base. The vanishing cream base contains 3-25% by weight of a fatty acid. Optionally, the composition can contain 0.1-10% by weight of a soap. If contained, the fatty acid is preferably a C10-C22 fatty acid, more preferably a C16-C18 fatty acid. Most preferably, the fatty acid is stearic acid or palmitic acid or a mixture thereof, and the soap is preferably a potassium salt of the fatty acid mixture. The fatty acid is often hystric acid, which is essentially (generally about 90-95%) a mixture of 45% stearic acid and 55% palmitic acid. The most preferred cream is a cream having 3-25% by weight of a fatty acid and 0.1-10% by weight of a soap.

[0026] Preferably, the composition includes an emollient. Examples of emollients that may be used in the leave-on composition include stearyl alcohol, glyceryl monoricinoleate, mink oil, isopropyl isostearate, isobutyl palmitate, isocetyl stearate, oleyl alcohol, isopropyl laurate, hexyl laurate, decyl oleate, octadecane-2-ol, isocetyl alcohol, eicosanyl alcohol, behenyl alcohol, cetyl palmitate, silicone oils such as dimethylpolysiloxane, dibutyl sebacate, isopropyl myristate, palmitate, oleyl alcohol, isocetyl alcohol, eicosanyl alcohol, behenyl alcohol, cetyl palmitate, silicone oils such as dimethylpolysiloxane, dibutyl sebacate, isopropyl myristate, palmitate, oleyl alcohol, isocetyl alcohol, eicosanyl alcohol, behenyl alcohol, isocetyl palmitate, silicone oils such as dimethylpolysiloxane, dibutyl sebacate, isopropyl myristate, palmitate, oleyl alcohol, isocetyl alcohol, eicosanyl alcohol, behenyl alcohol, isocetyl palmitate, oleyl alcohol, isocetyl alcohol, eicosanyl alcohol, behenyl alcohol, isocetyl palmitate, silicone oils such as dimethylpolysiloxane, dibutyl sebacate, isopropyl myristate, palmitate, oleyl alcohol, isocet ... Isopropyl myristate, isopropyl stearate, butyl stearate, polyethylene glycol, triethylene glycol, lanolin, cocoa butter, corn oil, cottonseed oil, olive oil, palm kernel oil, rapeseed oil, safflower seed oil, evening primrose oil, soybean oil, sunflower seed oil, avocado oil, sesame seed oil, coconut oil, peanut oil, castor oil, acetylated lanolin alcohol, petrolatum, mineral oil, butyl myristate, isopropyl linoleate, lauryl lactate, myristyl lactate, decyl oleate, myristyl myristate, and mixtures thereof.

[0027] Preferably, the composition includes a solvent. Examples of solvents that can be used in the composition include ethyl alcohol, isopropanol, acetone, ethylene glycol monoethyl ether, diethylene glycol monobutyl ether, diethylene glycol monoethyl ether, and mixtures thereof. The composition can include a polyhydric alcohol that can be selected from one or more of glycerin, 1,3-butylene glycol, propylene glycol, 1,3-propanediol, pentylene glycol, hexylene glycol, and sorbitol.

[0028] Preferably, the composition comprises a powder. Examples of powders that may be used in the composition include chalk, talc, Fuller's earth, kaolin, starch, gum, colloidal silica, sodium polyacrylate, tetraalkyl and / or trialkylaryl ammonium smectites, chemically modified magnesium aluminum silicate, organically modified montmorillonite clay, hydrated aluminum silicate, fumed silica, carboxyvinyl polymer, sodium carboxymethylcellulose, ethylene glycol monostearate, and mixtures thereof.

[0029] Preferably, the composition includes a preservative to protect against the growth of potentially harmful microorganisms. Examples of ingredients that can be used as preservatives in the composition include alkyl esters of parahydroxybenzoic acid, hydantoin derivatives, propionate salts, and various quaternary ammonium compounds. More preferably, ingredients that can be used as preservatives in the composition are sodium benzoate, iodopropynyl butylcarbamate, methylisothiazolinone, iodopropynyl butylcarbamate, phenoxyethanol, methylparaben, propylparaben, imidazolidinyl urea, sodium dehydroacetate, ethylhexylglycerin, benzyl alcohol, alkanediols, and mixtures thereof. When present in the composition, the preservative is preferably added in an amount of 0.001-5% by weight, more preferably 0.01-3% by weight, most preferably 0.02-2% by weight, and most preferably 0.25-1.5% by weight.

[0030] Preferably, the composition contains a range of other optional ingredients including antioxidants, binders, buffers, colorants, astringents, fragrances, opacifiers, conditioners, exfoliants, pH adjusters, skin sensates, skin soothing agents and skin healing agents.

[0031] It is within the scope of the present invention that the compositions claimed herein are environmentally friendly and therefore free of certain ingredients that are increasingly implicated in long-term environmental harm. Thus, one aspect of the present invention relates to compositions that are free of sulfate surfactants. Another aspect relates to compositions herein that are free of preservatives. Yet another aspect relates to compositions that are free of acrylate polymers. Also within the scope of the present invention are compositions that are free of titanium dioxide. Green (i.e., biodegradable chelating agents) are preferred for use in such compositions, i.e., the compositions are preferably free of traditional chelating agents such as EDTA. "Free" of a particular ingredient according to the present invention means that the composition contains less than 0.1% by weight of the composition, preferably less than 0.05% by weight, and more preferably less than 0.01% by weight of the composition. They are optimally absent in the composition.

[0032] The packaging of the compositions of the present invention may be a patch, a bottle, a tube, a roll-ball applicator, a propellant-driven aerosol device, a squeeze container, or a jar with a lid.

[0033] In an alternative embodiment, the present invention relates to the use of a composition according to the invention for lightening the skin.

[0034] In yet another aspect, the present invention relates to a method of lightening human skin, the method comprising the step of applying to the skin a composition according to the present invention.

[0035] In yet another aspect of the present invention there is provided a method of providing microbiome benefit to the skin, said method comprising the step of applying to the skin a composition according to the present invention.

[0036] Inulin is known as a prebiotic that has beneficial effects on the gut microbiome. Inulin stimulates the growth and activity of health-promoting microorganisms while simultaneously inhibiting pathogenic gut bacteria. Beneficial microorganisms ferment inulin, producing acids including short-chain fatty acids, lowering the pH in the large intestine and inhibiting pathogenic bacteria. The inventors have found that including inulin in the topical compositions of the present invention aids in the production of beneficial metabolites that promote skin health. For example, S. epidermidis fermented inulin can provide depigmentation benefits.

[0037] The invention will now be illustrated with the following non-limiting examples. EXAMPLES

[0038] Examples A-F, Example 1, Example 2: % Cellular Melanin Content of Various Combinations of Actives vs. Control

[0039] Various samples containing actives were prepared and the % cellular melanin content was measured. The protocol for measuring cellular melanin is summarized below.

[0040] Cell culture:

[0041] Primary neonatal human epidermal melanocytes were obtained from Life Technologies. Melanocytes were maintained in Medium 254 supplemented with human melanocyte growth supplement (MGM). HaCaT keratinocytes were maintained in DMEM medium containing 10% heat-inactivated FBS. All media were also supplemented with 10 U / mL penicillin G and 0.1 mg / mL streptomycin sulfate. Both cell types were maintained at 37°C in a humidified incubator with a 5% CO2 atmosphere. Cell maintenance and subculture were performed according to the manufacturer's instructions.

[0042] To set up the co-cultures, 40,000 cells each of HaCaT keratinocytes and melanocytes were mixed in 1 mL of a 1:1 mixture of MGM:KGM (KGM: Epilife medium supplemented with human keratinocyte growth supplement) and directly seeded per well into a 12-well Nunc plate.

[0043] Addition of active substances:

[0044] The active substances were prepared in culture medium and the test concentrations were added to the cells along with the relevant controls 24 hours after seeding. After 72 hours of treatment with the active substances, measurements of cell viability (using the calcein method) and cellular melanin content were performed as described below.

[0045] Cell viability assay:

[0046] Briefly, spent medium was removed and cells were washed once with 0.4 mL of phosphate-buffered saline. Fresh 1 μM calcein-acetoxymethyl in phosphate-buffered saline was added to each well. Plates were incubated at 37°C in a 5% CO2 incubator for 30 min. Calcein fluorescence was measured using a TECAN M1000 plate reader (excitation wavelength 490 nm, emission wavelength 520 nm).

[0047] Melanin Content Assay:

[0048] After calcein fluorescence measurements were obtained, cells were drained and 0.15 mL of fresh 1N NaOH (in 10% DMSO) was added per well. Cells were lysed by resuspension and incubation (60°C, 1 h). 0.1 mL of this lysate was then transferred to a new 384-well plate and the OD at 405 nm was measured on a TECAN M1000 plate reader. Melanin content was calculated as % cellular melanin relative to control.

[0049] The following samples were prepared as listed in Table 1 and the % melanin content of each was measured as listed in Table 1.

[0050] [Table 1]

[0051] COM1 represents a combination of niacinamide (0.0122%) + 4-hexylresorcinol (0.00002%) + retinyl propionate (0.00003%)

[0052] * indicates p<0.05 vs. Example D # indicates p<0.05 vs. Example F $ indicates p<0.05 vs. Example C

[0053] The data in Table 1 above show that the compositions according to the present invention (Examples 1 and 2) provide significantly better reduction in cellular melanin content compared to each individual component. The results of Example 2 are comparable to the highly effective positive control (Example E).

[0054] It should be understood that the above experiments were performed in an in vitro assay to evaluate the % melanin at the cellular level. The concentrations actually used to prepare the compositions for topical use are expected to vary widely. The concentrations are generally orders of magnitude higher due to the following reasons that affect the difference in bulk concentration compared to the cellular concentration: The compositions may be formulated as emulsions or gels that contain numerous additional ingredients. The concentrations of the desired actives in the oil phase and the water phase are expected to be very different. They may also have very different physical and hydrodynamic properties such as partition coefficients, diffusion rates, convective transport rates, rheological properties, etc. Thus, the concentrations used when formulating the compositions are expected to be significantly different, often orders of magnitude higher, than the cellular concentration at which the experiments were performed.

Claims

1. 1. A personal care composition comprising: (a) a retinoic acid precursor selected from one or more of retinyl ester, retinol, retinal, and retinoic acid; (b) a carboxylic acid functionalized heteroaromatic compound selected from one or more of nicotinic acid, picolinic acid, nicotinate, niacinamide, and picolinamide; (c) alkylresorcinols; (d) inulin; and (e) a cosmetically acceptable vehicle; A composition comprising:

2. The composition of claim 1, comprising 0.001 to 10% by weight of a retinoic acid precursor.

3. The composition of claim 1 comprising from 0.01 to 10 weight percent of a carboxylic acid functionalized heteroaromatic compound.

4. 2. The composition of claim 1, wherein the alkylresorcinol comprises one or more of 4-hexylresorcinol, 4-ethylresorcinol, 4-phenylethylresorcinol, 4-cyclopentylresorcinol, 4-cyclohexylresorcinol, and 4-octylresorcinol.

5. The composition of claim 1 comprising from 0.001 to 10 weight percent of an alkylresorcinol.

6. The composition of claim 1 comprising 0.01 to 10% inulin.

7. 10. The composition of claim 1, further comprising an oil preferably selected from one or more of isopropyl myristate, isopropyl palmitate, caprylic / capric triglyceride and benzyl alcohol.

8. Acrylate / C １０－３０ The composition of claim 1 further comprising an emulsifying polymer selected from one or more of an alkyl acrylate crosspolymer and a carbomer, preferably at 0.01 to 5% by weight of the composition.

9. 2. The composition according to claim 1, in the form of a serum, cream, lotion or gel, preferably in the form of a serum or cream.

10. A method for providing luminosity with an even skin tone to the skin, said method comprising the step of applying to the skin a composition according to any one of claims 1 to 9.

11. 10. A method of providing microbiome benefits to skin, comprising the step of applying to the skin a composition according to any one of claims 1 to 9.

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