Compositions suitable for skin care

Abstract

To provide a composition stable to several factors such as light, especially UV light without using EDTA or a salt thereof.SOLUTION: A composition comprising: (a) at least one polyglutamic acid or salts thereof; (b) at least one compound selected from vitamin B6, derivatives thereof, and mixtures thereof; and (c) at least one chelating agent other than EDTA or salts thereof.SELECTED DRAWING: None

Description

[Technical Field]

[0001] The present invention relates to compositions, preferably cosmetic compositions, more preferably dermocosmetic compositions, that are stable to several factors such as light, especially UV light. [Background technology]

[0002] There are a wide variety of skin care active ingredients used in the field of cosmetic and dermatological compositions. Hyaluronic acid ingredients, polyglutamic acid or its salts, vitamin B6 or its derivatives are examples of skin care active ingredients.

[0003] Cosmetic and dermatological compositions, especially those containing multiple skin care active ingredients, are preferably stable to several factors such as light, especially UV light.

[0004] EDTA (ethylenediaminetetraacetic acid) salts are commonly used as chelating agents to capture metal ions in compositions that may promote the oxidation of components in the composition. However, EDTA salts can be difficult for microorganisms to decompose.

[0005] Furthermore, it is important to develop new cosmetic compositions by promoting the use of renewable raw materials and / or materials with a good naturalness index and / or materials of natural origin and / or materials that can be more easily degraded by microorganisms in the environment. [Prior art documents] [Patent documents]

[0006] [Patent Document 1] EP-A-317542 [Patent Document 2] EP-A-399133 [Patent Document 3] EP-A-516102 [Patent Document 4] EP-A-509382

Patent Document 5

Patent Document 6

Patent Document 7

Patent Document 8

Non-Patent Document

[0007]

Non-Patent Document 1

Non-Patent Document 2

Non-Patent Document 3

Non-Patent Document 4

Non-Patent Document 5

Summary of the Invention

Problems to be Solved by the Invention

[0008] The object of the present invention is to provide a composition that is stable to several factors, such as light, especially UV light, without the use of EDTA or its salts. [Means for solving the problem]

[0009] The above object of the present invention is to (a) at least one polyglutamic acid or salt thereof; (b) at least one compound selected from vitamin B6, its derivatives, and mixtures thereof; and (c) at least one chelating agent other than EDTA or its salts This can be achieved by a composition, preferably a cosmetic composition, more preferably a dermocosmetic composition, comprising:

[0010] The amount of (a) polyglutamic acid or a salt thereof in the composition according to the present invention may be within the range of 0.001% by mass to 3% by mass, preferably 0.005% by mass to 1% by mass, and more preferably 0.01% by mass to 0.5% by mass, relative to the total mass of the composition.

[0011] The (b) compound may be selected from salts and esters of pyridoxine, preferably salts of pyridoxine, more preferably inorganic acid addition salts of pyridoxine, even more preferably pyridoxine hydrochloride.

[0012] The amount of the (b) compound in the composition according to the present invention may be in the range of 0.001% by mass to 1% by mass, preferably 0.005% by mass to 0.5% by mass, and more preferably 0.01% by mass to 0.1% by mass, relative to the total mass of the composition.

[0013] (c) The chelating agent is preferably selected from (poly)amino(poly)carboxylic acids.

[0014] More preferably, the (c) chelating agent is selected from the group consisting of trisodium ethylenediaminedisuccinate, trisodium NTA, pentasodium pentetate, and mixtures thereof.

[0015] The amount of (c) chelating agent in the composition according to the present invention may be within the range of 0.01% by mass to 5% by mass, preferably 0.05% by mass to 3% by mass, and more preferably 0.1% by mass to 1% by mass, relative to the total mass of the composition.

[0016] The composition according to the present invention may further comprise (d) at least one neutralized poly(meth)acrylic acid polymer.

[0017] The amount of (d) neutralized poly(meth)acrylic acid polymer in the composition according to the present invention can be in the range of 0.01% to 5% by weight, preferably 0.05% to 4% by weight, more preferably 0.1% to 3% by weight, relative to the total weight of the composition.

[0018] The composition according to the present invention may further comprise (e) at least one hydrophobic inorganic filler.

[0019] The amount of (e) hydrophobic inorganic filler in the composition according to the present invention can be in the range of 0.01% by mass to 3% by mass, preferably 0.05% by mass to 1% by mass, and more preferably 0.1% by mass to 0.5% by mass, relative to the total mass of the composition.

[0020] The composition according to the present invention may further comprise (f) at least one hyaluronic acid component selected from the group consisting of hyaluronic acid, hyaluronic acid salts, hyaluronic acid derivatives, hyaluronic acid derivative salts, and mixtures thereof.

[0021] The composition according to the present invention may further comprise (g) at least one polysaccharide.

[0022] The composition according to the invention may be oil-free or may comprise at least one oil in an amount of not more than 1% by weight, preferably not more than 0.5% by weight, more preferably not more than 0.1% by weight relative to the total weight of the composition.

[0023] The present invention also relates to a method for treating keratinous materials, comprising the step of applying a composition according to the present invention to the keratinous materials. DETAILED DESCRIPTION OF THE INVENTION

[0024] As a result of extensive research, the present inventors have discovered that it is possible to provide a composition that is stable against several factors such as light, particularly UV light.

[0025] Thus, one aspect of the present invention is (a) at least one polyglutamic acid or salt thereof; (b) at least one compound selected from vitamin B6, its derivatives, and mixtures thereof; and (c) at least one chelating agent other than EDTA or its salts A composition comprising:

[0026] The compositions according to the invention are stable to several factors such as light, especially UV light.

[0027] The compositions according to the invention are suitable for skin care.

[0028] The compositions according to the invention are stable to light, in particular UV light, so that no light-induced change in the appearance of the composition is observable.

[0029] The compositions according to the present invention are stable both immediately after preparation of the compositions and long after preparation of the compositions, so that the compositions according to the present invention are stable over time and can be stored for long periods of time, even in sunlight, for example in summer.

[0030] Furthermore, the composition according to the present invention allows vitamin B6 or a derivative thereof to penetrate the skin well.

[0031] By "good skin penetration" is meant herein that vitamin B6 or a derivative thereof can penetrate deeper into the skin, preferably into the epidermis, more preferably into the dermis. Therefore, the composition according to the present invention is preferred for use in skin cosmetics.

[0032] (a) Polyglutamic acid or a salt thereof can maintain water or moisture in the skin. Therefore, when applied to the skin, the composition according to the present invention comprising (a) polyglutamic acid or a salt thereof can maintain water or moisture in the skin.

[0033] However, (a) polyglutamic acid or a salt thereof may affect the stability of the composition of the present invention under light, and therefore the composition of the present invention contains (c) a chelating agent to enhance the stability of the composition of the present invention against light.

[0034] Compositions according to the present invention may also provide additional benefits.

[0035] The composition according to the present invention can provide a good feeling in use, in particular good spreadability during application and smoothness after application.

[0036] Good spreadability here means ease of spreading with less friction, i.e., smooth spreading.

[0037] Smoothness after application herein means a smooth feeling with no or little stickiness after application. The term "stickiness" refers to the property of providing a tacky feel to the skin.

[0038] (a) polyglutamic acid or a salt thereof is viscous, water-absorbent, and film-forming. Therefore, the composition according to the present invention containing (a) polyglutamic acid or a salt thereof can have good fluidity, which can contribute to good spreadability with little friction during application. Meanwhile, after application, (a) polyglutamic acid or a salt thereof can contribute to long-lasting moisturizing and smoothness.

[0039] When the composition according to the present invention contains (d) a neutralized poly(meth)acrylic acid polymer, (d) the neutralized poly(meth)acrylic acid polymer in the composition according to the present invention can contribute to improving the spreadability, moisturizing feeling, and / or smoothness after application of the composition.

[0040] When the composition according to the present invention contains (e) a hydrophobic inorganic filler, the (e) hydrophobic inorganic filler in the composition according to the present invention can contribute to improving the spreadability of the composition and / or smoothness after application. Furthermore, when the (e) hydrophobic inorganic filler can absorb oil or sebum, it can provide a matte finish.

[0041] When the composition according to the present invention contains the (f) hyaluronic acid component, the yield stress of the composition according to the present invention can be reduced, thereby enhancing the spreadability of the composition according to the present invention. In addition, the (f) hyaluronic acid component can further enhance the moisturizing effect.

[0042] The present invention will now be described in more detail.

[0043] [Composition] The composition according to the present invention comprises (a) at least one polyglutamic acid or salt thereof; (b) at least one compound selected from vitamin B6, its derivatives, and mixtures thereof; and (c) at least one chelating agent other than EDTA or its salts Includes.

[0044] (Polyglutamic acid or its salt) The composition according to the present invention comprises (a) at least one type of polyglutamic acid or a salt thereof. A single type of polyglutamic acid or a salt thereof may be used, or two or more different types of polyglutamic acid or a salt thereof may be used in combination.

[0045] (a) Polyglutamic acid or a salt thereof has the following chemical formula (1): ROOC-CH2CH2-CH(-COOR)-NH-[CO-CH2CH2-CH(-COOR)-NH-] n -CO-CH2CH2-CH(-COOR)-NH2(1) (wherein R independently represents a hydrogen atom, an alkali metal atom such as a sodium atom or a potassium atom, or an ammonium group such as a tetramethylammonium group or a tetraethylammonium group; n is an integer of 2 or more, preferably 4 or more, and more preferably 6 or more. It may have a chemical structure represented by:

[0046] The polyglutamic acid or salt thereof represented by the above chemical formula (1) can be called γ-polyglutamic acid or a salt thereof because the carboxyl group at the γ position and the amino group at the α position form a peptide bond.

[0047] (a) It may be preferable that the molecular weight of polyglutamic acid or a salt thereof is 1000 or more and the degree of polymerization is 8 or more ("n" in the above chemical formula (1) is 6 or more).

[0048] (a) It may be more preferable that the molecular weight of polyglutamic acid or a salt thereof is 100,000 or more and the degree of polymerization is 770 or more ("n" in the above chemical formula (1) is 768 or more).

[0049] (a) It may be even more preferable that the molecular weight of polyglutamic acid or a salt thereof is 500,000 or more and the degree of polymerization is 3840 or more ("n" in the above chemical formula (1) is 3838 or more).

[0050] (a) There is no upper limit to the molecular weight of polyglutamic acid or its salt.

[0051] However, the molecular weight of (a) polyglutamic acid or a salt thereof may be 5,000,000 or less, and the degree of polymerization may be 38,500 or less ("n" in the above chemical formula (1) is 38,498 or less), and preferably, the molecular weight of (a) polyglutamic acid or a salt thereof may be 3,000,000 or less, and the degree of polymerization may be 23,080 or less ("n" in the above chemical formula (1) is 23,078 or less).

[0052] (a) Glutamic acid, which is a constituent amino acid of polyglutamic acid or its salts, may be in the D-form, the L-form, or the racemic form. However, considering market availability, biocompatibility, and biodegradability, it may be preferable to use polyglutamic acid composed only of L-glutamic acid or polyglutamic acid composed of a mixture of L- and D-glutamic acid. However, polyglutamic acid composed of D-glutamic acid, which has the same effect but is less degradable, may also be used.

[0053] The method for producing (a) polyglutamic acid or a salt thereof is not particularly limited. For example, organic synthesis using a peptide synthesizer, organic synthesis by polymerization of glutamic acid N-carboxyanhydride, or organic synthesis by polymerization of N-benzyloxycarbonylglutamic anhydride can be used. Alternatively, microorganisms belonging to the genus Bacillus capable of producing gamma-polyglutamic acid (particularly Bacillus subtilis, Bacillus anthracis, Bacillus licheniformis, and Bacillus megaterium capable of producing gamma-polyglutamic acid) can also be used in a fermentation method for producing (a) polyglutamic acid or a salt thereof.

[0054] As the medium used in the fermentation method, in addition to natural media composed of natural products, such as shochu stillage medium and soybean extract medium, any synthetic medium or any semi-synthetic medium composed of any one of the following components: carbon sources, such as glucose, fructose, galactose, sucrose, maltose, mannose, lactose, glycerol and starch; inorganic nitrogen sources, such as ammonium sulfate, ammonium phosphate, and ammonium chloride; Organic nitrogen sources, such as glutamic acid or a salt thereof, aspartic acid or a salt thereof, Major inorganic salts, such as sodium chloride, magnesium sulfate, monopotassium phosphate, phosphorus and disodium phosphate, trace inorganic salts containing atoms such as iron, copper, zinc, cobalt, nickel, boron, manganese, molybdenum, tin, selenium, silicon, arsenic, vanadium, chromium, and fluorine; Vitamins, such as biotin, nicotinamide, calcium pantothenate, thiamine, riboflavin, and pyridoxine hydrochloride; Organic acids, such as citric acid, tartaric acid, malic acid, and glycolic acid, and Natural product extracts, such as yeast extract, meat extract, potato extract, tomato extract, and soy peptides may be used in any concentration.

[0055] Regarding the culture conditions for the microorganisms, the temperature can be set within a range of 20° C. to 37° C., and may be further controlled during the microbial growth process and the polyglutamic acid production process. The pH can be set within a range of 5.0 to 8.0, and may be further controlled during the microbial growth process and the polyglutamic acid production process.

[0056] As a method for extracting and purifying (a) polyglutamic acid or a salt thereof from the culture solution after completion of the culture, known methods, such as acid precipitation, solution precipitation, and membrane purification, can be selected at will.

[0057] (a) As the polyglutamic acid or a salt thereof, it is preferable to use polyglutamic acid or an alkali metal salt thereof, such as sodium polyglutamate.

[0058] Commercially available products may be used as the (a) polyglutamic acid or a salt thereof. Examples of (a) polyglutamic acid or a salt thereof include Hyafactor™-PGA-HM sold by Bloomage Biotechnology Co., Ltd. in China, and Bio-PGA solutions HE, HB, LB, and LE, and Bio-PGA Na powder sold by Ichimaru Pharcos Co., Ltd. in Japan.

[0059] The amount of (a) polyglutamic acid or a salt thereof in the composition according to the present invention can be 0.001% by mass or more, preferably 0.005% by mass or more, more preferably 0.01% by mass or more, relative to the total mass of the composition.

[0060] On the other hand, the amount of (a) polyglutamic acid or a salt thereof in the composition according to the present invention may be 3% by mass or less, preferably 1% by mass or less, more preferably 0.5% by mass or less, relative to the total mass of the composition.

[0061] Therefore, the amount of (a) polyglutamic acid or a salt thereof in the composition according to the present invention can be within the range of 0.001% by mass to 3% by mass, preferably 0.005% by mass to 1% by mass, and more preferably 0.01% by mass to 0.5% by mass, relative to the total mass of the composition.

[0062] (Vitamin B6 and / or its derivatives) The composition according to the present invention comprises at least one compound selected from (b) vitamin B6, its derivatives, and mixtures thereof. A single type of (b) compound may be used, or two or more different types of (b) compounds may be used in combination.

[0063] Preferably, vitamin B6 is selected from pyridoxine, pyridoxal, pyridoxamine, and mixtures thereof. It is preferred to use pyridoxine as vitamin B6.

[0064] In a preferred embodiment, the vitamin B6 derivative is selected from vitamin B6 salts, preferably vitamin B6 acid addition salts, more preferably vitamin B6 inorganic acid addition salts. Examples of vitamin B6 salts include pyridoxine HCl, pyridoxal HCl, and pyridoxamine 2HCl. Pyridoxine HCl is particularly preferred.

[0065] In another preferred embodiment, the derivative of vitamin B6 is an ester of vitamin B6, preferably a fatty acid ester and a phosphate ester of vitamin B6, more preferably a C6-C 18 It can be selected from fatty acid monoesters, diesters, or triesters, and phosphate esters. Examples of vitamin B6 fatty acid esters include pyridoxine dilaurate, pyridoxine distearate, pyridoxine dipalmitate, pyridoxine trilaurate, pyridoxine tristearate, and pyridoxine tripalmitate. Examples of vitamin B6 phosphate esters include pyridoxine phosphate and pyridoxal phosphate.

[0066] Preferably, the (b) compound is selected from salts and esters of pyridoxine, preferably salts of pyridoxine, more preferably inorganic acid addition salts of pyridoxine, even more preferably pyridoxine hydrochloride (pyridoxine HCl).

[0067] The amount of (b) compound in the composition according to the present invention may be 0.001% by weight or more, preferably 0.005% by weight or more, more preferably 0.01% by weight or more, relative to the total weight of the composition.

[0068] On the other hand, the amount of the (b) compound in the composition according to the present invention may be 1% by weight or less, preferably 0.5% by weight or less, more preferably 0.1% by weight or less, relative to the total weight of the composition.

[0069] Therefore, the amount of the (b) compound in the composition according to the present invention can be in the range of 0.001% by mass to 1% by mass, preferably 0.005% by mass to 0.5% by mass, and more preferably 0.01% by mass to 0.1% by mass, relative to the total mass of the composition.

[0070] (chelating agent) The composition according to the present invention includes (c) at least one chelating agent other than EDTA or a salt thereof. A single type of such chelating agent may be used, or two or more different types of such chelating agents may be used in combination.

[0071] (c) Chelating agents include: (i) (Poly)amino(poly)carboxylic acids, such as compounds with the following INCI names: diethylenetriaminepentaacetic acid (DTPA), ethylenediaminedisuccinic acid (EDDS) and trisodium ethylenediaminedisuccinate, e.g. Octaquest from Octel. E30, trisodium nitrilotriacetic acid (trisodium NTA), pentetic acid pentasodium, ethylenediamine-N,N'-diglutaric acid (EDDG), glycinamide-N,N'-disuccinic acid (GADS), 2-hydroxypropylenediamine-N,N'-disuccinic acid (HPDDS), ethylenediamine-N,N'-bis(ortho-hydroxyphenylacetic acid) (EDDHA), N,N'-bis(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid (HBED), nitrilotriacetic acid (NTA), methylglycine diacetic acid (MGDA), N-2-hydroxyethyl-N,N-diacetic acid and glyceryl iminodiacetic acid (reference EP-A-31754 2 and EP-A-399133), iminodiacetic acid-N-2-hydroxypropylsulfonic acid and aspartic acid N-carboxymethyl N-2-hydroxypropyl-3-sulfonic acid (as described in EP-A-516102), beta-alanine-N,N'-diacetic acid, aspartic acid-N,N'-diacetic acid and aspartic acid-N-monoacetic acid (as described in EP-A-509382), chelating agents based on iminodisuccinic acid (IDSA) (as described in EP-A-509382), ethanoldiglycinic acid, phosphonobutanetricarboxylic acids, for example the compound sold under the reference Bayhibit AM by Bayer, tetrasodium glutamate diacetate (GLDA), for example Dissolvine GL38 or 45S from Akzo Nobel, (ii) chelating agents based on mono- or polyphosphonic acids, such as compounds with the following INCI names: diethylenetriaminepenta(methylenephosphonic acid) (DTPMP), ethane-1-hydroxy-1,1,2-triphosphonic acid (E1HTP), ethane-2-hydroxy-1,1,2-triphosphonic acid (E2HTP), ethane-1-hydroxy-1,1-diphosphonic acid (EHDP), ethane-1,1,2-triphosphonic acid (ETP), ethylenediaminetetramethylenephosphonic acid (EDTMP), and hydroxyethane-1,1-diphosphonic acid (HEDP), and (iii) Chelating agents based on polyphosphates, such as compounds with the following INCI names: sodium tripolyphosphate (STP), tetrasodium diphosphate, hexametaphosphate, sodium metaphosphate, phytic acid, its salts and derivatives; and A mixture of these.

[0072] (c) The chelating agent is preferably chosen from (poly)amino(poly)carboxylic acids, ie aminocarboxylic acids having one or more amino moieties and / or one or more carboxy moieties.

[0073] More preferably, the (c) chelating agent is selected from the group consisting of trisodium ethylenediaminedisuccinate, trisodium NTA, pentasodium pentetate, and mixtures thereof.

[0074] Even more preferably, the (c) chelating agent is trisodium ethylenediaminedisuccinate.

[0075] The amount of (c) the chelating agent in the composition according to the present invention may be 0.01% by mass or more, preferably 0.05% by mass or more, more preferably 0.1% by mass or more, relative to the total mass of the composition.

[0076] On the other hand, the amount of (c) the chelating agent in the composition according to the present invention may be 5% by mass or less, preferably 3% by mass or less, and more preferably 1% by mass or less, relative to the total mass of the composition.

[0077] The amount of (c) chelating agent in the composition according to the present invention may be within the range of 0.01% by mass to 5% by mass, preferably 0.05% by mass to 3% by mass, and more preferably 0.1% by mass to 1% by mass, relative to the total mass of the composition.

[0078] (Neutralized poly(meth)acrylic acid polymer) The composition according to the present invention may comprise (d) at least one neutralized poly(meth)acrylic acid polymer. A single type of neutralized poly(meth)acrylic acid polymer may be used, or two or more different types of neutralized poly(meth)acrylic acid polymers may be used in combination.

[0079] The (d) neutralized poly(meth)acrylic acid polymer may have water-absorbing properties, and therefore, the (d) neutralized poly(meth)acrylic acid polymer may be a water-absorbing polymer.

[0080] In one particular embodiment of the present invention, (d) the neutralized poly(meth)acrylic acid polymer may have a water absorption capacity of 10 g or more, preferably 20 g or more, more preferably 50 g or more, and / or 2,000 g or less, preferably 1,500 g or less, more preferably 1,000 g or less, per gram of polymer at 25°C and 1 atm.

[0081] (d) The neutralized poly(meth)acrylic acid polymer may be provided in the form of particles, preferably spherical particles. 50 The average primary particle diameter of "D" is not particularly limited, but is generally 0.1 μm or more, preferably 0.5 μm or more, more preferably 1 μm or more, and / or 200 μm or less, preferably 100 μm or less, more preferably 50 μm or less. 50 " is used herein to mean that 50% by volume of the particles, based on the total volume of the particles, are D 50 50% by volume of the particles based on the total volume of the particles is D 50 The particle size is greater than D.50 The value can be determined by laser diffraction, for example using a laser diffraction particle size distribution analyzer, such as a Mastersizer 2000 from Malvern Corp.

[0082] The (d) neutralized poly(meth)acrylic acid polymer may be water-soluble, and therefore, the (d) neutralized poly(meth)acrylic acid polymer may be included in the aqueous phase of the composition according to the present invention when the composition according to the present invention includes (h) water.

[0083] The (d) neutralized poly(meth)acrylic acid polymer can be wholly or partially neutralized. Preferably, the (d) neutralized poly(meth)acrylic acid polymer is partially neutralized. The (d) neutralized poly(meth)acrylic acid polymer can be wholly or partially in the form of a salt, preferably a metal salt, more preferably an alkali metal salt, and even more preferably a sodium salt. The molar ratio of the neutralized portion to the non-neutralized portion is not particularly limited, but is generally 10 mol% or more, 20 mol% or more, 30 mol% or more, or 40 mol% or more, and / or 90 mol% or less, 80 mol% or less, 70 mol% or less, or 60 mol% or less.

[0084] The (d) neutralized poly(meth)acrylic acid polymer may be a homopolymer or a copolymer. Preferably, the (d) neutralized poly(meth)acrylic acid polymer is a homopolymer.

[0085] (d) The neutralized poly(meth)acrylic acid polymer has the following formula (I): -[CH(R 1 )-C(R 2 )(COO-M + )]- (I) (In the formula, R 1 and R 2 are the same or different and represent a hydrogen atom or a (C1-C6) alkyl group, such as methyl, and preferably R 1 and R 2 represents a hydrogen atom, M + is H + or a cationic counterion, preferably an alkali metal cation, an alkaline earth metal cation, or an ammonium ion, more preferably M + represents an alkali metal cation, e.g., a sodium cation) The compound may have a repeating unit represented by:

[0086] The repeat number of the above repeating unit according to formula (I) is 2 or more.

[0087] (d) Neutralized poly(meth)acrylic acid polymers having repeating units according to formula (I) are represented by formula (Ia): HC(R 1 )=C(R 2 )-COO - M + (Ia) (In the formula, R 1 , R 2 and M + is as defined above) can be derived by polymerizing several identical (in which case it is a homopolymer) or several different (in which case it is a copolymer) monomers selected from the following in the presence of at least one polymerization initiator (e.g., a UV initiator) to obtain a polymer of formula (I) as defined above.

[0088] (d) The neutralized poly(meth)acrylic acid polymer may be crosslinked.

[0089] Crosslinking of the (d) neutralized poly(meth)acrylic acid polymer can be carried out, for example, by applying at least one crosslinking agent to the (d) neutralized poly(meth)acrylic acid polymer by spraying.

[0090] In a preferred embodiment of the present invention, the (d) neutralized poly(meth)acrylic acid polymer is a crosslinked homopolymer. In particular, mention may be made of sodium polyacrylate sold under the name AQUPEC MG N40R, which is crosslinked and partially neutralized, also known as sodium carbomer.

[0091] The amount of (d) neutralized poly(meth)acrylic acid polymer in the composition according to the present invention may be 0.01% by weight or more, preferably 0.05% by weight or more, more preferably 0.1% by weight or more, based on the total weight of the composition.

[0092] On the other hand, the amount of (d) neutralized poly(meth)acrylic acid polymer in the composition according to the present invention may be 5% by weight or less, preferably 4% by weight or less, more preferably 3% by weight or less, based on the total weight of the composition.

[0093] Therefore, the amount of (d) neutralized poly(meth)acrylic acid polymer in the composition according to the present invention can be in the range of 0.01% to 5% by weight, preferably 0.05% to 4% by weight, more preferably 0.1% to 3% by weight, relative to the total weight of the composition.

[0094] (hydrophobic inorganic filler) The composition according to the present invention may contain (e) at least one hydrophobic inorganic filler. A single type of hydrophobic inorganic filler may be used, or two or more different types of hydrophobic inorganic fillers may be used in combination.

[0095] The term "mineral filler" here should be understood to mean colorless or white inorganic particles that are insoluble in the liquid components that may be present in the composition according to the invention, regardless of the temperature at which the composition is prepared.

[0096] The inorganic filler may include metal oxides, preferably silica, titanium oxide, zinc oxide, and mixtures thereof.

[0097] Inorganic fillers suitable for the present invention can be, for example, fillers with an average particle size of less than 100 μm, in particular between 1 μm and 50 μm, for example between 4 μm and 20 μm.

[0098] The term "hydrophobic" means that the inorganic filler can be dispersed individually in oil so that no agglomerates are formed.

[0099] (e) The hydrophobic inorganic filler may be porous or non-porous.

[0100] (e) The hydrophobic inorganic filler may or may not be capable of absorbing (and / or adsorbing) oil or liquid fatty substances, such as sebum (from the skin). (e) The hydrophobic inorganic filler is preferably capable of absorbing (and / or adsorbing) oil or liquid fatty substances, such as sebum (from the skin).

[0101] (e) The hydrophobic inorganic filler may have an oil absorption capacity of 100 ml / 100 g or more, preferably 150 ml / 100 g or more, and more preferably 200 ml / 100 g or more.

[0102] (e) The amount of oil absorbed (and / or adsorbed) by a hydrophobic inorganic filler can be determined as follows.

[0103] The amount of oil absorbed (and / or adsorbed) can be measured according to the method for determining the oil absorption of powders described in NF standard T 30-022. It corresponds to the amount of oil absorbed / adsorbed on the available surface of the powder by measuring the wetting point Wp, which corresponds to the amount of oil that needs to be added to 100 g of powder to obtain a homogeneous paste.

[0104] A quantity of m = 2 g of powder is placed on a glass plate, and then oil (such as ester oil or silicone oil) is added dropwise. After adding 4-5 drops of oil to the powder, mix using a spatula and continue adding oil until an agglomerate of oil and powder is formed. At this point, add the oil drop by drop, and then grind the mixture with the spatula. Stop adding oil when a firm, smooth paste is obtained. This paste should be able to be spread on the glass plate without cracking or forming lumps. The volume Vs (expressed in ml) of the oil used is then noted. The oil absorption corresponds to the Vs / m ratio.

[0105] Alternatively, oil absorption capacity can be measured according to JIS-K6217-4.

[0106] (e) The hydrophobic inorganic filler may have at least one inorganic core and at least one hydrophobic coating.

[0107] The inorganic core may comprise at least one material selected from the group consisting of silica, silicates, perlite, boron nitride, magnesium carbonate, magnesium hydroxide, titanium oxide, zinc oxide, kaolin, talc, and mixtures thereof.

[0108] The hydrophobic coating can be formed by a hydrophobic treating agent, which may be selected from, inter alia, fatty acids, such as stearic acid; metal soaps, such as aluminum dimyristate, aluminum salts of hydrogenated tallow glutamate; amino acids; N-acyl amino acids or salts thereof; lecithin, isopropyl triisostearyl titanate, mineral waxes, and mixtures thereof.

[0109] The N-acylamino acid may contain an acyl group containing 8 to 22 carbon atoms, such as 2-ethylhexanoyl, caproyl, lauroyl, myristoyl, palmitoyl, stearoyl, or cocoyl. Salts of these compounds may be aluminum, magnesium, calcium, zirconium, zinc, sodium, or potassium salts. The amino acid may be, for example, lysine, glutamic acid, or alanine.

[0110] The term "alkyl" referred to in the compounds listed above denotes, inter alia, alkyl groups containing from 1 to 30 carbon atoms, preferably from 5 to 16 carbon atoms.

[0111] Preferably, (e) the hydrophobic inorganic filler is selected from hydrophobically modified metal oxides, more preferably from hydrophobically modified silica, titanium oxide, zinc oxide, and mixtures thereof. The hydrophobically modified metal oxide may have at least one hydrophobic coating on the metal oxide particles.

[0112] Preferably, (e) the hydrophobic inorganic filler can be selected from hydrophobic silica, especially silica silylate.

[0113] The term "hydrophobic silica" is understood to mean any silica particle whose surface has been treated to make it hydrophobic. Hydrophobic silica or hydrophobic silica particles may have at least one hydrophobic coating on the silica particle.

[0114] (e) The hydrophobic inorganic filler is preferably selected from hydrophobic silica aerogel particles, more preferably hydrophobic silica silylate aerogel.

[0115] Hydrophobic silica, especially silica silylate, can be based on silica aerogel, a porous material obtained by replacing the liquid component of silica gel with air (by drying).

[0116] They are generally synthesized via the sol-gel method in a liquid medium and then dried, usually by extraction with a supercritical fluid, the most commonly used supercritical fluid being supercritical CO2. This type of drying makes it possible to avoid pore and material shrinkage. The sol-gel method and various drying procedures are described in detail in Brinker CJ and Scherer GW, Sol-Gel Science, New York, Academic Press, 1990.

[0117] Aerogels are highly porous materials. Herein, silica aerogel generally refers to solid silica with a porous structure obtained by drying wet silica gel while maintaining the solid silica network, thereby replacing the media contained in wet silica gel with air. Porosity is the amount of air contained in the apparent volume of the material, expressed as a volume percentage. The hydrophobic silica aerogel of the present invention can have a porosity of 60% or more, preferably 70% or more, and more preferably 80% or more.

[0118] Hydrophobic silica aerogel particles are 500~1,500m 2 / g, preferably 600 to 1,200m 2 / g, more preferably 600 to 800m 2 Specific surface area (SW) per unit mass in the range of / g, and / or A size expressed as a volume average diameter (D[0.5]) in the range of 1 to 1500 μm, preferably 1 to 1000 μm, more preferably 1 to 100 μm, particularly 1 to 30 μm, even more preferably 5 to 25 μm, even more preferably 5 to 20 μm, and even more preferably 5 to 15 μm. may present.

[0119] The specific surface area per unit mass can be determined by a nitrogen absorption method known as the BET (Brunauer-Emmett-Teller) method, which is described in The Journal of the American Chemical Society, Vol. 60, p. 309, February 1938, and corresponds to the international standard ISO 5794 / 1 (Annex D). The BET specific surface area corresponds to the total specific surface area of ​​the particles under consideration.

[0120] The size of hydrophobic silica aerogel particles can be measured by static light scattering using a commercially available particle size analyzer, the Malvern MasterSizer 2000. The data are processed based on the Mie scattering theory. This theory, which is rigorous for isotropic particles, allows the determination of the "effective" particle size for non-spherical particles. This theory is described, inter alia, in the publication "Light Scattering by Small Particles" by Van de Hulst, H.C., Chapters 9 and 10, Wiley, New York, 1957.

[0121] The hydrophobic silica aerogel particles are advantageously 0.04 g / cm 3 ~0.10g / cm 3 , preferably 0.05 g / cm 3 ~0.08g / cm 3 The packing density (r) can be in the range of

[0122] In the context of the present invention, this density, known as packing density, can be assessed according to the following protocol: 40g of powder was poured into a graduated measuring cylinder. The measuring cylinder was then placed in a Stampf Volumeter Stav 2003 instrument. The graduated cylinder is then subjected to a series of 2500 filling operations (this operation is repeated until the volume difference between two consecutive tests is less than 2%), The final volume Vf of the packed powder is then measured directly in the measuring cylinder. The packing density is determined by the w / Vf ratio (Vf is in cm 3 where w is expressed in g), which in this case is 40 / Vf.

[0123] For the preparation of hydrophobic silica aerogel particles surface-modified by silylation, reference may be made to document US Pat. No. 7,470,725.

[0124] In particular, hydrophobic silica aerogel particles that are surface-modified with trimethylsilyl groups are used.

[0125] (e) Hydrophobic inorganic fillers that may be mentioned include polydimethylsiloxane-coated amorphous silica microspheres, especially those sold under the names Sunsphere® H33 and Sunsphere® H53 (oil absorption equal to 400 ml / 100 g), precipitated silica powders surface-treated with mineral waxes, such as precipitated silica treated with polyethylene waxes, especially those sold under the name Acematt OR 412 by Evonik-Degussa (oil absorption equal to 398 ml / 100 g), and silica silylate sold under the name VM-2270 by Dow (oil absorption equal to 1,040 ml / 100 g).

[0126] (e) As hydrophobic inorganic filler, it is preferred to use silica silylate sold by Dow under the name VM-2270, the particles of which have an average size in the range of 5 to 15 μm and a viscosity of 600 to 800 μm. 2 / g.

[0127] The hydrophobic silica aerogel particles can be characterized by the spherical shape of each particle. Due to this spherical shape, the hydrophobic silica aerogel particles can provide good smoothness to cosmetic compositions. The sphericity of the hydrophobic silica aerogel can be determined by the average circularity.

[0128] The spherical hydrophobic silica aerogel particles may have an average circularity of 0.8 or more, preferably 0.82 or more. The spherical hydrophobic silica aerogel may have an average circularity of less than 1, preferably 0.99 or less, more preferably 0.98 or less, even more preferably 0.97 or less, even more preferably 0.96 or less, and most preferably 0.95 or less.

[0129] The "average circularity" can be determined by image analysis. In particular, the "average circularity" can be the arithmetic mean of the circularities obtained by image analysis of scanning electron microscope (SEM) images of 2,000 or more aerogel particles observed at 1,000x magnification by secondary electron detection using a scanning electron microscope (SEM).

[0130] The "roundness" of each aerogel particle is calculated using the following formula: C=4πS / L 2 (In the formula, C represents the circularity, S represents the area (projected area) of the aerogel particle in the image, and L represents the perimeter (outer perimeter) of the aerogel particle in the image.) The closer the average circularity is to 1, the more spherical the shape of each particle becomes.

[0131] The hydrophobic silica aerogel particles that can be used as the hydrophobic inorganic filler (e) according to the present invention are preferably silylated silica aerogel particles (INCI name: silica silylate).Preferably, the hydrophobic silica aerogel particles may be those described in JP 2014-088307, JP 2014-218433, or JP 2018-177620.

[0132] As the inorganic hydrophobic oil-absorbing powder, it is preferred to use hydrophobic aerogel of silica silylate.

[0133] The hydrophobicity of the silica silylated hydrophobic aerogel is determined by adding a hydrophobizing agent having the following formula to the surface of the silica: ≡Si-OH (wherein the symbol "≡" represents the remaining three valences of the Si atom) by reacting the silanol groups with silanol groups represented by the formula: (≡Si-O-) (4-n) SiR n (wherein n is an integer of 1 to 3, each R is independently a hydrocarbyl group, and when n is 2 or more, two or more R may be the same or different.) can be obtained by converting the aryl group into a group represented by

[0134] The hydrophobizing agent may be a silylating agent. Therefore, according to a preferred embodiment, in the hydrophobic aerogel of silylated silica, the silica particles may be surface-modified by silylation. Examples of the silylating agent include a treatment agent having one of the following formulas (1) to (3):

[0135] Formula (1): R n Six (4-n) (wherein n represents an integer of 1 to 3, R represents a hydrocarbyl group, and X represents a group that can be eliminated from the molecule by cleaving the bond to the Si atom during reaction with a compound having a hydroxyl group (i.e., a leaving group); when n is 2 or more, each R may be different, and when n is 2 or less, each X may be different).

[0136] Formula (2):

[0137] [ka]

[0138] (In the formula, R 1 represents an alkylene group, and R 2 and R 3 each independently represents a hydrocarbyl group; R 4 and R 5 independently represent a hydrogen atom or a hydrocarbyl group).

[0139] Formula (3):

[0140] [ka]

[0141] (In the formula, R 6 and R 7 each independently represents a hydrocarbyl group, m represents an integer of 3 to 6, and R 6 If there are two or more R 6 may be different, R 7 If there are two or more R 7 may be different).

[0142] In the above formula (1), R is a hydrocarbyl group, preferably a hydrocarbyl group having 1 to 10 carbon atoms, more preferably a hydrocarbyl group having 1 to 4 carbon atoms, and particularly preferably a methyl group.

[0143] Examples of the leaving group represented by X include halogen atoms such as chlorine and bromine, alkoxy groups such as methoxy and ethoxy, and groups represented by -NH-SiR3 (wherein R is defined as R in formula (1)).

[0144] Specific examples of the hydrophobizing agent represented by the above formula (1) include chlorotrimethylsilane, dichlorodimethylsilane, trichloromethylsilane, monomethyltrimethoxysilane, monomethyltriethoxysilane, and hexamethyldisilazane.

[0145] Most preferably, from the standpoint of favorable reactivity, chlorotrimethylsilane, dichlorodimethylsilane, trichloromethylsilane, and / or hexamethyldisilazane may be used.

[0146] The number of bonds between the Si atom and the silanol groups on the silica backbone varies depending on the number of leaving groups X (4-n). For example, when n is 2, the following bonds are formed: (≡Si-O-)2SiR2

[0147] When n is 3, the following combination occurs: ≡Si-O-SiR3

[0148] In this way, the silanol groups can be silylated, thereby rendering them hydrophobic.

[0149] In the above formula (2), R 1 may be an alkylene group, preferably an alkylene group having 2 to 8 carbon atoms, particularly preferably an alkylene group having 2 to 3 carbon atoms.

[0150] In the above formula (2), R 2 and R 3 are independently hydrocarbyl groups, and the same preferred groups as those of R in formula (1) can be mentioned. 4 represents a hydrogen atom or a hydrocarbyl group, and when it is a hydrocarbyl group, the same preferred groups as those for R in formula (1) can be mentioned. When silica gel is treated with a compound represented by formula (2) (cyclic silazane), the reaction with the silanol groups causes cleavage of the Si-N bond, resulting in the formation of the following bond on the surface of the silica skeleton in the gel: (≡Si-O-)2SiR 2 R 3

[0151] In this way, the silanol groups can be silylated with the cyclic silazane of the above formula (2), thereby making them hydrophobic.

[0152] Specific examples of the cyclic silazane represented by the above formula (3) include hexamethylcyclotrisilazane and octamethylcyclotetrasilazane.

[0153] In the above formula (3), R 6 and R 7are independently hydrocarbyl groups, and the same preferred groups as those represented by R in formula (2) can be mentioned. m represents an integer of 3 to 6. When silica gel is treated with a compound represented by formula (3) (cyclic siloxane), the following bond is formed on the surface of the silica skeleton in the gel. (≡Si-O-)2SiR 6 R 7

[0154] In this way, the silanol groups can be silylated with the cyclic siloxane of the above formula (3), thereby making them hydrophobic.

[0155] Specific examples of the cyclic siloxane represented by the above formula (3) include hexamethylcyclotrisiloxane, octamethylcyclotetrasiloxane, and decamethylcyclopentasiloxane.

[0156] Hydrophobic aerogels of silica silylate can be prepared by producing a silica sol, converting the sol to a gel, aging the gel, washing the aged gel, replacing the water in the washed gel with a solvent, treating the gel with a hydrophobizing agent, and drying the hydrophobized silica.

[0157] Silica silylate hydrophobic aerogel is 200m 2 / g or more, preferably 400m 2 / g or more, more preferably 500m 2 / g or more, as determined by the BET method, 2 / g or less, preferably 1000m 2 / g or less, more preferably 800m 2 / g or less, as determined by the BET method.

[0158] The hydrophobic silica aerogel of silica silylate may have a pore volume, as determined by the BJH method, of 1 ml / g or more, preferably 2 ml / g or more, more preferably 3 ml / g or more, or a pore volume, as determined by the BJH method, of 10 ml / g or less, preferably 8 ml / g or less, more preferably 7 ml / g or less. The hydrophobic silica aerogel of silica silylate may have a peak pore radius, as determined by the BJH method, of 5 nm or more, preferably 10 nm or more, more preferably 12 nm or more, or a peak pore radius, as determined by the BJH method, of 50 nm or less, preferably 40 nm or less, more preferably 30 nm or less.

[0159] "Pore volume determined by the BJH method" refers to the pore volume derived from pores having a pore radius of 1 nm to 100 nm, obtained by analyzing the nitrogen adsorption isotherm obtained by the same method as described above in "Specific surface area determined by the BET method" using the BJH method (Barrett, EP, Joyner, LG, Halenda, PP, J. Am. Chem. Soc. 73, 373 (1951)). "Peak pore radius determined by the BJH method" refers to the value of the pore radius that gives a peak in the pore distribution curve (volume distribution curve), obtained by analyzing the nitrogen adsorption isotherm obtained by the same method as above using the BJH method, plotting the differential of the cumulative pore volume with respect to the logarithm of the pore radius on the vertical axis and the pore radius on the horizontal axis.

[0160] The silica silylate hydrophobic aerogel may have an average particle size of 0.5 μm or more, preferably 1 μm or more, more preferably 2 μm or more, and may have an average particle size of 30 μm or less, preferably 20 μm or less, more preferably 15 μm or less, as determined by image analysis.

[0161] The "average particle size" here can be measured by image analysis. Specifically, the "average particle size" value is the arithmetic mean of the equivalent circular diameters obtained by image analysis of scanning electron microscope (SEM) images of, for example, 2,000 or more aerogel particles observed at 1,000x magnification by secondary electron detection using a scanning electron microscope (SEM). The "equivalent circular diameter" of each aerogel particle is the diameter of a circle having an area equal to the area (projected area) of the aerogel particle in the image.

[0162] Preferably, the silica silylate hydrophobic aerogel, as explained above, may have an oil absorption capacity, measured at the wet point, of 2 ml / g or more, preferably 3 ml / g or more, more preferably 4 ml / g or more, and most preferably 5 ml / g or more, and may have an oil absorption capacity, measured at the wet point, of 12 ml / g or less, preferably 10 ml / g or less, more preferably 8 ml / g or less, and most preferably 7 ml / g or less.

[0163] (e) The hydrophobic inorganic filler is preferably selected from hydrophobically modified metal oxides, more preferably hydrophobic silica, and even more preferably silica silylate.

[0164] The amount of (e) hydrophobic inorganic filler in the composition according to the present invention can be 0.01% by weight or more, preferably 0.05% by weight or more, more preferably 0.1% by weight or more, relative to the total weight of the composition.

[0165] On the other hand, the amount of (e) hydrophobic inorganic filler in the composition according to the present invention may be 3% by mass or less, preferably 1% by mass or less, more preferably 0.5% by mass or less, relative to the total mass of the composition.

[0166] Therefore, the amount of (e) hydrophobic inorganic filler in the composition according to the present invention can be in the range of 0.01% by mass to 3% by mass, preferably 0.05% by mass to 1% by mass, and more preferably 0.1% by mass to 0.5% by mass, relative to the total mass of the composition.

[0167] (Hyaluronic acid ingredient) The composition according to the present invention may comprise (f) at least one hyaluronic acid component selected from the group consisting of hyaluronic acid, hyaluronic acid salts, hyaluronic acid derivatives, hyaluronic acid derivative salts, and mixtures thereof. A single type of hyaluronic acid component may be used, or two or more different types of hyaluronic acid components may be used in combination.

[0168] Hyaluronic acid is the predominant glycosaminoglycan found in the skin. Thus, fibroblasts predominantly synthesize collagen, non-collagen matrix glycoproteins (fibronectin, laminin), proteoglycans, and elastin. Keratinocytes, for their part, predominantly synthesize sulfated glycosaminoglycans and hyaluronic acid. Hyaluronic acid is also called hyaluronan.

[0169] Hyaluronic acid exists in free state in epidermis and dermis, and it is responsible for the turgor of skin.This polysaccharide can actually hold a large volume of water, up to 1000 times its mass.In this sense, hyaluronic acid plays an important role in increasing the amount of water bound in tissue, and also in the mechanical properties and wrinkle formation of skin.

[0170] Hyaluronic acid has the following chemical formula:

[0171] [ka]

[0172] It can be expressed as:

[0173] In the context of the present invention, the term "hyaluronic acid" refers in particular to the basic unit of hyaluronic acid of the formula:

[0174] [ka]

[0175] It is the smallest part of hyaluronic acid, containing a disaccharide dimer, namely D-glucuronic acid and N-acetylglucosamine.

[0176] The term "hyaluronic acid", in the context of the present invention, includes linear polymers comprising the polymer units described above linked together in chains via alternating β(1,4) and β(1,3) glycosidic bonds, with molecular weights (MW) that can range between 380 and 13,000,000 daltons, depending primarily on the source and / or preparation method from which the hyaluronic acid is obtained.

[0177] The term "hyaluronic acid" in the context of the present invention also includes hydrolyzed hyaluronic acid.

[0178] The term "hyaluronic acid derivatives" in the context of the present invention includes hyaluronic acid esters, in particular those in which all or part of the carboxylic acid groups of the acid function are esterified with oxyethylenated alkyls or alcohols, containing 1 to 20 carbon atoms, and in particular the degree of substitution of hyaluronic acid at the level of D-glucuronic acid is in the range of 0.5% to 50%.

[0179] Mention may in particular be made of the methyl, ethyl, n-propyl, n-pentyl, benzyl and dodecyl esters of hyaluronic acid, which are described in particular by D. Campoccia et al., "Semisynthetic resorbable materials from hyaluronan esterification", Biomaterials 19 (1998) pp. 2101-2127.

[0180] In one embodiment, the hyaluronic acid derivative may be, for example, acetylated hyaluronic acid.

[0181] The term "hyaluronic acid derivatives" also includes, in the context of the present invention, cationic hyaluronic acid.

[0182] Cationic hyaluronic acid contains at least one cationic moiety. The cationic moiety is a trialkylammonium group, e.g., -N + (CH3)3. The cationic moiety may include at least one hydroxyl group. An example of a cationic group is -CH2-CH(OH)-CH2-N + (CH3)3 is an example.

[0183] An example of a cationic hyaluronic acid is hydroxypropyltrimonium hyaluronate.

[0184] Hyaluronic acid salts or hyaluronic acid derivative salts can include alkali metal salts such as sodium salts and potassium salts, alkaline earth metal salts such as magnesium salts, ammonium salts, and mixtures thereof.

[0185] The molecular weight of the (f) hyaluronic acid component is not limited. The molecular weight of the (f) hyaluronic acid component can be 5 kDa or more, preferably 20 kDa or more, and more preferably 100 kDa or more. The molecular weight of the (f) hyaluronic acid component can be 20 MDa or less, preferably 10 MDa or less, and more preferably 2,000 kDa or less. Therefore, the molecular weight of the (f) hyaluronic acid component can be 5 kDa to 20 MDa, preferably 20 kDa to 10 MDa, and more preferably 100 kDa to 2,000 kDa.

[0186] Unless otherwise defined in the description, "molecular weight" may mean weight average molecular weight.

[0187] (f) Hyaluronic acid components are in particular sold under the trade names HyActive™ (MW: 10-150 kDa) by Centipro, Cristalhyal® (MW: 1-1.4 MDa) by Givaudan, Nutra™ HA (MW: 907,600 Da) by Bioland, Nutra™ HAF (MW: 74,600 Da) by Bioland, Oligo™ HA (MW: 0.5-10.1 kDa) by Bioland, D-Factor™ (MW: 380 Da) by Res Pharma or Hybloom™ Sodium Hyaluronate (HA-T) (MW: The hyaluronic acid may be hyaluronic acid supplied under the trade name of 1,000 kDa to 1,800 kDa.

[0188] A single hyaluronic acid component having a single molecular weight or a combination of two or more hyaluronic acid components having different molecular weights can be used as the (f) hyaluronic acid component.

[0189] (f) The hyaluronic acid component is preferably a hyaluronate, more preferably an alkali metal hyaluronate, such as sodium hyaluronate.

[0190] The amount of the (f) hyaluronic acid component in the composition according to the present invention can be 0.001% by weight or more, preferably 0.005% by weight or more, and more preferably 0.01% by weight or more, relative to the total weight of the composition.

[0191] On the other hand, the amount of the (f) hyaluronic acid component in the composition according to the present invention may be 3% by mass or less, preferably 1% by mass or less, more preferably 0.5% by mass or less, relative to the total mass of the composition.

[0192] Therefore, the amount of the (f) hyaluronic acid component in the composition according to the present invention can be within the range of 0.001% to 3% by mass, preferably 0.005% to 1% by mass, and more preferably 0.01% to 0.5% by mass, relative to the total mass of the composition.

[0193] (polysaccharide) The composition according to the present invention may comprise (g) at least one polysaccharide. When two or more polysaccharides are used, they may be the same or different.

[0194] When the composition according to the present invention contains (h) water, the (g) polysaccharide may be present in the aqueous phase of the composition according to the present invention. The (g) polysaccharide may function as a hydrophilic thickener that can thicken the aqueous phase of the composition according to the present invention.

[0195] (g) The polysaccharide is preferably derived from a microorganism or a plant.

[0196] (g) Polysaccharides derived from microorganisms refer to polysaccharides produced by microorganisms such as bacteria.

[0197] Examples of (g) polysaccharides derived from microorganisms include cardulan, xanthan gum, gellan gum, dextran, pullulan, sclerotium gum, and mixtures thereof.

[0198] The (g) polysaccharide derived from a microorganism may preferably be selected from the group consisting of sclerotium gum, xanthan gum, and mixtures thereof. Fermented polysaccharides, such as biosaccharide gum-1, biosaccharide gum-2, and biosaccharide-4, may also be used.

[0199] On the other hand, (g) polysaccharides derived from plants refer to polysaccharides obtained from plants or algae.

[0200] Examples of (g) polysaccharides of plant origin that can be used according to the invention include, inter alia: a) algae extracts, such as alginates, carrageenans and agar-agar, and mixtures thereof. Examples of carrageenans that may be mentioned include Satiagum UTC30® and UTC10® from the company Degussa, and an alginate that may be mentioned is sodium alginate sold under the name Kelcosol® by the company ISP; b) gums, such as guar gum and its non-ionic derivatives (hydroxypropyl guar), gum arabic, konjac gum or mannan gum, tragacanth gum, ghatti gum, karaya gum or locust bean gum; examples that may be mentioned include the guar gum sold under the name Jaguar HP105® by the company Rhodia, the mannan sold by the company GfN and konjac gum® (1% gluconomannan), c) modified or unmodified starches, such as those obtained from cereals such as wheat, corn or rice, from legumes such as blonde pea, from tubers such as potato or cassava, and tapioca starch; dextrins, such as corn dextrin; examples that may be mentioned in particular include rice starch Remy DR I® sold by the company Remy; corn starch B® from the company Rockete; potato starch modified with 2-chloroethylaminodipropionic acid and neutralized with sodium hydroxide, sold under the name Structure Solanace® by the company National Starch; and native tapioca starch powder sold under the name Tapioca pure® by the company National Starch. d) dextrins, such as those extracted from corn and sold under the trademark Index® by National Starch; e) cellulose and its derivatives, in particular alkylcelluloses, hydroxyalkylcelluloses, and alkylhydroxyalkylcelluloses; in particular methylcellulose, hydroxyethylcellulose, ethylhydroxyethylcellulose, and carboxymethylcellulose. Examples that may be mentioned include stearyl and cetyl hydroxyethylcellulose. Examples of cetyl hydroxyethylcellulose that may be mentioned include Polysurf 67CS® and Natrosol Plus 330® from Aqualon. and mixtures thereof.

[0201] Preferably, the plant-derived polysaccharide (g) can be selected from algae extracts, gums and cellulose derivatives, and mixtures thereof. More preferably, agar, locust bean gum, mannan konjac gum, cetyl or stearyl hydroxyethyl cellulose, and tapioca starch can be used.

[0202] The (g) polysaccharide derived from a plant may be an algae extract selected from alginate, carrageenan, agar, and mixtures thereof. Preferably, alginate or agar, or mixtures thereof, are used.

[0203] (g) The plant-derived polysaccharides may be selected from gums such as guar gum, gum arabic, mannan, and konjac gum, and locust bean gum, and mixtures thereof.

[0204] The (g) polysaccharide derived from a plant may be a modified or unmodified starch selected from wheat starch, corn starch, rice starch, potato starch, and tapioca starch, and mixtures thereof.

[0205] The (g) polysaccharide derived from a plant may be dextrin, such as corn dextrin.

[0206] The plant-derived polysaccharide (g) may be a cellulose derivative. The cellulose derivative may in particular be a (C1-C3) hydroxyalkylcellulose, especially a (C1-C3) hydroxyalkylcellulose modified with a hydrophobic chain, in particular with a hydrophobic group containing 8 to 30 carbon atoms. According to one embodiment, the hydrophobic substituent used is a C8-C 30 , preferably C 10 ~C 22 It may be an alkyl, arylalkyl or alkylaryl group. Preferably, the hydrophobic substituent according to the present invention is a saturated C 10 ~C 22 , preferably C 16 ~C 20 Alkyl chains, such as cetyl (C 16 ), stearyl (C 18 ) and behenyl (C 20 ) groups. According to a preferred embodiment, the hydrophobic substituent according to the invention may be a cetyl group. These cellulose derivatives containing a hydrophobic substituent according to the invention may have a viscosity, measured in a solution containing 1% by weight of polymer in water at 25°C, preferably between 100 and 100,000 mPas, preferably between 200 and 20,000 mPas, as conventionally determined at 6 rpm using a Brookfield LVT type viscometer with a No. 3 spindle. Among the cellulose derivatives containing a hydrophobic substituent that can be used in the compositions according to the invention, preferred mention may be made of cetyl hydroxyethylcellulose sold by Aqualon / Hercules under the names Natrosol Plus Grade 330 CS and Polysurf 67 CS (INCI name: cetyl hydroxyethylcellulose).

[0207] Preferably, the (g) plant-derived polysaccharide is selected from non-cellulosic polysaccharides.

[0208] Preferably, (g) the polysaccharide is selected from the group consisting of polysaccharides derived from plants, polysaccharides derived from microorganisms, and mixtures thereof.

[0209] More preferably, (g) the polysaccharide is selected from the group consisting of algae extracts, gums and cellulose derivatives, sclerotium gum, xanthan gum, fermented polysaccharides such as biosaccharide gum-1, biosaccharide gum-2 and biosaccharide-4, and mixtures thereof.

[0210] Even more preferably, (g) the polysaccharide is selected from the group consisting of sclerotium gum, xanthan gum, fermented polysaccharides such as biosaccharide gum-1, biosaccharide gum-2, and biosaccharide-4, and mixtures thereof.

[0211] The amount of (g) polysaccharide in the composition according to the present invention can be 0.001% by mass or more, preferably 0.005% by mass or more, and more preferably 0.01% by mass or more, relative to the total mass of the composition.

[0212] On the other hand, the amount of (g) polysaccharide in the composition according to the present invention may be 3% by mass or less, preferably 2% by mass or less, and more preferably 1% by mass or less, relative to the total mass of the composition.

[0213] The amount of (g) polysaccharide in the composition according to the present invention can be within the range of 0.001% by mass to 3% by mass, preferably 0.005% by mass to 2% by mass, and more preferably 0.01% by mass to 1% by mass, relative to the total mass of the composition.

[0214] (water) The composition according to the present invention may also comprise (h) water.

[0215] The amount of (h) water in the composition according to the present invention can be 50% by mass or more, preferably 60% by mass or more, and more preferably 70% by mass or more, based on the total mass of the composition.

[0216] On the other hand, the amount of (h) water in the composition according to the present invention may be 95% by mass or less, preferably 90% by mass or less, more preferably 85% by mass or less, based on the total mass of the composition.

[0217] The amount of (h) water in the composition according to the present invention can be within the range of 50% by mass to 95% by mass, preferably 60% by mass to 90% by mass, and more preferably 70% by mass to 85% by mass, relative to the total mass of the composition.

[0218] (Polyol) The composition according to the present invention may comprise at least one polyol. A single type of polyol may be used, but two or more different types of polyols may also be used in combination.

[0219] The term "polyol" as used herein refers to an alcohol having two or more hydroxy groups and does not include sugars or their derivatives. Sugar derivatives include sugar alcohols obtained by reducing one or more carbonyl groups of a sugar, and sugars or sugar alcohols in which the hydrogen atom in one or more hydroxy groups has been replaced with at least one substituent, such as an alkyl group, a hydroxyalkyl group, an alkoxy group, an acyl group, or a carbonyl group.

[0220] The polyol is a C2-C hydroxyl group containing at least two hydroxyl groups, preferably 2 to 5 hydroxyl groups. 12 It may be a polyol, preferably a C2 to C9 polyol.

[0221] The polyol may be a natural or synthetic polyol. The polyol may have a linear, branched or cyclic molecular structure.

[0222] The polyol may be selected from glycerin and its derivatives, and glycol and its derivatives, and preferably from the group consisting of glycerin, diglycerin, polyglycerin, ethylene glycol, diethylene glycol, propylene glycol, dipropylene glycol, butylene glycol, pentylene glycol, hexylene glycol, 1,3-propanediol, 1,5-pentanediol, and polyethylene glycol (5 to 50 ethylene oxide groups).

[0223] The polyol may be present in an amount ranging from 0.01% to 25% by weight, preferably from 0.1% to 20% by weight, for example from 1% to 15% by weight, relative to the total weight of the composition according to the invention.

[0224] (Other optional ingredients) The compositions according to the invention may also contain effective amounts of other optional ingredients previously known elsewhere in cosmetic compositions, such as preservatives and co-preservatives, vitamins or provitamins other than vitamin B6, fragrances, plant extracts, etc.

[0225] The composition according to the present invention may further comprise at least one organic solvent, preferably miscible with water. Examples of organic solvents include C1-C4 alkanols such as ethanol and isopropanol, aromatic alcohols such as benzyl alcohol and phenoxyethanol, similar products, and mixtures thereof.

[0226] The organic solvent may be present in an amount in the range of 0.01% by weight or more, preferably 0.1% by weight or more, more preferably 1% by weight or more, relative to the total weight of the composition according to the invention.

[0227] The organic solvent may be present in an amount ranging from 15% by weight or less, preferably from 10% by weight or less, more preferably from 5% by weight or less, relative to the total weight of the composition according to the invention.

[0228] The organic solvent may be present in an amount ranging from 0.01% to 15% by weight, preferably from 0.1% to 10% by weight, more preferably from 1% to 5% by weight, relative to the total weight of the composition according to the invention.

[0229] The composition according to the present invention may contain limited amounts of oil.

[0230] The amount of oil in the composition according to the invention may be at most 1% by weight, preferably at most 0.5% by weight, more preferably at most 0.1% by weight, relative to the total weight of the composition. It may be particularly preferred that the composition according to the invention is oil-free.

[0231] Preferably, the composition according to the invention contains very limited amounts of silicone.

[0232] Preferably, the amount of silicone, such as organopolysiloxane, in the composition according to the present invention is 1% by weight or less, preferably 0.1% by weight or less, more preferably 0.01% by weight or less, based on the total weight of the composition. It is particularly preferred that the composition according to the present invention is free of silicone.

[0233] According to a preferred embodiment, the composition according to the invention comprises, relative to the total weight of the composition: As component (a), 0.001% by mass to 3% by mass of polyglutamic acid or sodium polyglutamate; As component (b), 0.001% by mass to 1% by mass of vitamin B6 and / or a salt of vitamin B6, and As component (c), 0.01% by mass to 5% by mass of a (poly)amino(poly)carboxylic acid Includes.

[0234] According to a more preferred embodiment, the composition according to the invention comprises, relative to the total weight of the composition: As component (a), 0.01% by mass to 0.5% by mass of sodium polyglutamate; 0.01% to 0.1% by weight of pyridoxine HCl as component (b), and As component (c), 0.1% by mass to 1% by mass of trisodium ethylenediamine disuccinate, trisodium NTA, pentasodium pentetate, and mixtures thereof, more preferably trisodium ethylenediamine disuccinate. Includes.

[0235] (preparation) The composition according to the present invention can be prepared by mixing the essential components described above and, if necessary, the optional components described above.

[0236] The method and means for mixing the above essential components and optional components are not limited. Any conventional method and means can be used to mix the above essential components and optional components to prepare the composition according to the present invention. Conventional methods and means include a homogenizer, such as a turbine mixer.

[0237] (form) Compositions according to the invention may be in a variety of forms.

[0238] The composition according to the invention can be in the form of a fluid, for example a viscous liquid, at room temperature (25° C.) and atmospheric pressure (760 mm Hg).

[0239] When the composition according to the present invention comprises (d) a neutralized poly(meth)acrylic acid polymer and (h) water, the composition can be in the form of an aqueous gel because the (d) neutralized poly(meth)acrylic acid polymer can function as a hydrophilic thickener.

[0240] The compositions according to the invention may be transparent or translucent.

[0241] (pH) The pH of the compositions according to the present invention may be less than 7.0, preferably less than 6.5, more preferably less than 6.0.

[0242] The pH of the composition according to the present invention may be 3.0 or higher, preferably 3.5 or higher, more preferably 4.0 or higher.

[0243] For example, the pH of the composition according to the present invention may be from 3.0 to less than 7.0, preferably from 3.5 to less than 6.5, and more preferably from 4.0 to less than 6.0.

[0244] The pH of the composition according to the invention can be adjusted by adding at least one alkaline agent and / or at least one acid, or a salt thereof. The pH of the composition according to the invention can also be adjusted by adding at least one buffering agent.

[0245] [Method and Use] The composition according to the present invention is preferably a cosmetic composition, more preferably a cosmetic composition for keratinous materials such as the skin.

[0246] The composition according to the invention is suitable as a cosmetic skin care composition, for example, it can be used to moisturize the skin.

[0247] The composition according to the present invention is preferably a leave-on type. In other words, the composition according to the present invention is preferably applied to keratinous materials such as the skin without rinsing. Therefore, the composition according to the present invention is preferably not a cleansing composition.

[0248] The present invention also relates to a method, preferably a cosmetic method, for keratinous materials such as the skin, comprising the step of applying a composition according to the invention to the keratinous materials.

[0249] Cosmetic method here means a non-therapeutic beautifying method for caring for and / or making up the surfaces of keratinous materials such as the skin, preferably a non-therapeutic beautifying method for caring for the skin.

[0250] The method according to the invention is preferably not a cleansing method, and therefore preferably does not include a step of rinsing the composition according to the invention from keratinous materials such as the skin.

[0251] The present invention also relates to the use of a composition as defined above for caring for and / or making up the surfaces of keratinous materials such as the skin.

[0252] The present invention also provides (a) at least one polyglutamic acid or a salt thereof, and (b) at least one compound selected from vitamin B6, its derivatives, and mixtures thereof; for improving the stability of a composition to light, particularly UV light, in a composition comprising (c) It may involve the use of at least one chelating agent other than EDTA or its salts.

[0253] With respect to the composition according to the present invention, the above explanations regarding (a) polyglutamic acid or a salt thereof, (b) a compound selected from vitamin B6, a derivative thereof, and a mixture thereof, and (c) a chelating agent other than EDTA or a salt thereof can be applied to the above explanations regarding use.

[0254] The compositions cited in the above uses may include any of the optional components described above, such as components (d) to (h). [Example]

[0255] The present invention will now be described in more detail by way of examples, which should not be construed as limiting the scope of the invention.

[0256] (Example 1 and Comparative Example 1) [Preparation] The following compositions according to Example 1 and Comparative Example 1 shown in Table 1 were prepared by mixing the components shown in Table 1. The numerical values ​​of the amounts of the components shown in Table 1 are all based on "mass %" of the raw materials. Symbols such as (a) in Table 1 correspond to those in the claims.

[0257] [Table 1]

[0258] [evaluation] (UV stability) Each of the compositions according to Example 1 and Comparative Example 1 was filled into a glass bottle. UV light covering a wavelength range of 300 nm to 800 nm was irradiated onto the glass bottle for 24 hours at room temperature using an ATLAS SUNTEST CPS+ supplied by Toyo Seiki Seisakusho, Ltd. of Japan. Each composition was then inspected for changes in the appearance of the composition and evaluated according to the following criteria: Good: No difference after UV exposure Bad: Water separation observed after UV irradiation

[0259] The results are shown in Table 1.

[0260] (summary) The composition according to Example 1 was stable under UV light, while the composition according to Comparative Example 1 was unstable under UV light.

Claims

1. (a) at least one polyglutamic acid or salt thereof; (b) at least one compound selected from vitamin B6, its derivatives, and mixtures thereof; and (c) at least one chelating agent other than EDTA or its salts A composition, preferably a cosmetic composition, more preferably a dermocosmetic composition, comprising:

2. The composition according to claim 1, wherein the amount of (a) polyglutamic acid or a salt thereof in the composition is within the range of 0.001% by mass to 3% by mass, preferably 0.005% by mass to 1% by mass, and more preferably 0.01% by mass to 0.5% by mass, relative to the total mass of the composition.

3. 3. The composition according to claim 1 or 2, wherein the (b) compound is selected from salts and esters of pyridoxine, preferably salts of pyridoxine, more preferably inorganic acid addition salts of pyridoxine, even more preferably pyridoxine hydrochloride.

4. 4. The composition according to claim 1, wherein the amount of the (b) compound in the composition is within the range of 0.001% to 1% by weight, preferably 0.005% to 0.5% by weight, and more preferably 0.01% to 0.1% by weight, relative to the total weight of the composition.

5. 5. The composition according to claim 1, wherein the (c) chelating agent is selected from (poly)amino(poly)carboxylic acids.

6. 6. The composition of claim 1, wherein the (c) chelating agent is selected from the group consisting of trisodium ethylenediaminedisuccinate, trisodium NTA, pentasodium pentetate, and mixtures thereof.

7. The composition according to any one of claims 1 to 6, wherein the amount of (c) chelating agent in the composition is within the range of 0.01% to 5% by weight, preferably 0.05% to 3% by weight, and more preferably 0.1% to 1% by weight, relative to the total weight of the composition.

8. 8. The composition of claim 1, further comprising (d) at least one neutralized poly(meth)acrylic acid polymer, preferably selected from sodium carbomer.

9. 9. The composition according to claim 8, wherein the amount of (d) neutralized poly(meth)acrylic acid polymer in the composition is within the range of 0.01% to 5% by weight, preferably 0.05% to 4% by weight, and more preferably 0.1% to 3% by weight, relative to the total weight of the composition.

10. 10. The composition according to any one of claims 1 to 9, further comprising (e) at least one hydrophobic inorganic filler, preferably selected from hydrophobic silicas, in particular silica silylate.

11. The composition according to claim 10, wherein the amount of (e) the hydrophobic inorganic filler in the composition is within the range of 0.01% by weight to 3% by weight, preferably 0.05% by weight to 1% by weight, and more preferably 0.1% by weight to 0.5% by weight, relative to the total weight of the composition.

12. 12. The composition of claim 1, further comprising (f) at least one hyaluronic acid component selected from the group consisting of hyaluronic acid, hyaluronic acid salts, hyaluronic acid derivatives, hyaluronic acid derivative salts, and mixtures thereof.

13. 13. The composition of any one of claims 1 to 12, further comprising (g) at least one polysaccharide, preferably selected from the group consisting of algae extracts, gums and cellulose derivatives, sclerotium gum, xanthan gum, fermented polysaccharides such as biosaccharide gum-1, biosaccharide gum-2 and biosaccharide-4, and mixtures thereof.

14. 14. The composition according to any one of claims 1 to 13, which is oil-free or comprises at least one oil in an amount of at most 1% by weight, preferably at most 0.5% by weight, more preferably at most 0.1% by weight, relative to the total weight of the composition.

15. A method for treating keratinous materials, comprising the step of applying a composition according to any one of claims 1 to 14 to the keratinous materials.

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