Composition for improving fatigue and / or mood state

Abstract

To provide a highly versatile composition for improving fatigue and / or mood, which can be widely applied to food and beverages and other products. [Solution] The above problem can be solved by a composition for improving fatigue and / or mood, which contains inulin as an active ingredient.

Description

Technical Field

[0001] The present invention relates to a composition for improving fatigue and / or mood state.

Background Art

[0002] In recent years, due to the establishment of systems such as foods for specified health use and foods with functional claims, great attention has been paid to health functional foods and food materials having such functions. In the market, in addition to supplements, so-called health foods, many general foods displaying physiological functions have also come to be sold. Among such supplements or health food materials, there is dietary fiber. The Ministry of Health, Labour and Welfare has also recommended ingesting 20 g per day for adult men and 18 g per day for adult women of dietary fiber, and many general foods added with dietary fiber and described as being rich in dietary fiber, as well as foods displaying physiological functions, have been put on the market.

[0003] Dietary fiber is roughly classified into two types: insoluble dietary fiber and water-soluble dietary fiber. The typical physiological function of dietary fiber is an intestinal regulating action, but it has also been confirmed that water-soluble dietary fiber has other functions such as reduction of neutral fat and suppression of an increase in blood glucose level. It is considered that these functions contribute to the action of adjusting the intestinal environment, such as water-soluble dietary fiber serving as food for intestinal bacteria, increasing a group of bacteria called so-called good bacteria, and short-chain fatty acids being produced by these bacteria metabolizing water-soluble dietary fiber. …

[0004] Dietary fiber is roughly classified into two types: insoluble dietary fiber and water-soluble dietary fiber. The typical physiological function of dietary fiber is an intestinal regulating action, but it has also been confirmed that water-soluble dietary fiber has other functions such as reduction of neutral fat and suppression of an increase in blood glucose level. It is considered that these functions contribute to the action of adjusting the intestinal environment, such as water-soluble dietary fiber serving as food for intestinal bacteria, increasing a group of bacteria called so-called good bacteria, and short-chain fatty acids being produced by these bacteria metabolizing water-soluble dietary fiber.

[0005] In recent years, it has been gradually clarified that the brain and the intestine are related via the autonomic nervous system and humoral factors (such as hormones), and have been attracting attention. This relationship is called "brain-gut interaction". It is called the "gastrointestinal system," and information from the digestive tract is transmitted to the cerebrum via the nervous system, and abdominal discomfort can be associated with depression and anxiety. It has been suggested that it could potentially trigger any of these emotional changes.

[0006] However, much of the evidence for this is based on diseases such as irritable bowel syndrome and animals such as rats. This study demonstrated the possibility of a correlation between "gut bacteria-gut-brain" and the metabolism of gut bacteria. Various studies have been attempted to investigate the correlation between water-soluble dietary fiber and brain function, but no clear effect has been observed. No results have been obtained. For example, the short-chain fatty acids produced when dietary fiber is metabolized by intestinal bacteria Animal studies have shown that butyric acid, one of the compounds in the compound, has "antidepressant effects" (Patent Document 1). However, in human epidemiological studies, the amount of water-soluble dietary fiber intake and a self-assessment scale for depressive symptoms have been found to be related. No correlation has been found between CES-D and depressive mood. (Non-patent document 1)

[0007] Inulin, which is used worldwide as a water-soluble dietary fiber, is also related to mental health. The effect of this has been verified. For example, for obese women with mild to severe depression, 1 per day When subjects were given 0g of inulin and a placebo of maltodextrin, a significant difference was observed. In subjects whose weight decreased by more than 1.9 kg, regardless of whether they received inulin or placebo... An improvement in the HDRS score, a depression assessment scale, was observed. (Non-patent document 2) However, it contains 50% oligofructose, an inulin degradation product, and a chain length of 10 A fructan complex containing 50% inulin (~60) was administered to healthy individuals at a daily dose of 10g. It turns out that the HAD scale, which was developed to measure anxiety and depression in patients visiting the clinic, is a measure of anxiety and depression. Among the S indicators, anxiety was significantly increased, and HADS depression No improvement has been seen regarding ion. (Non-patent document 3) HDRS is Hamilton depression This refers to a disease assessment scale, and is not a diagnostic tool for depression, but rather a scale for evaluating the severity of depression. be.

[0008] Furthermore, in an epidemiological survey conducted by the Ministry of Health and Welfare in 1999, the percentage of people who felt fatigued was Approximately 60% of the working population suffers from chronic fatigue that lasts for more than six months. It was believed to exist and attracted attention. In recent years, research on brain function, neural mechanisms, and fatigue has progressed. The effects of food ingredients on fatigue have also been evaluated, for example, vitamin C and coenzyme Q1 Anti-fatigue effects have been demonstrated with substances such as 0, citrate, and imidazole dipeptide.

[0009] Regarding the anti-fatigue effects of dietary fiber, glucans from oats and polysaccharides from maca have been shown in animal studies. Therefore, it has been shown that it may be effective in reducing fatigue or improving muscular endurance, but this has not been demonstrated in humans. It's not like that. [Prior art documents] [Patent Documents]

[0010] [Patent Document 1] Japanese Patent Publication No. 2018-184366 [Non-patent literature]

[0011] [Non-Patent Document 1] Nutrition Volume 32, Issue 5, May 2016, Pages 584-589 "Dietary fiber intake and depressive symptoms in Japanese employees: The Furukawa Nutrition and Health Study" [Non-Patent Document 2] Nutritional Neuroscience Jun 26; Pages 1-15,2019「Calorie restriction in combination with prebiotic supplementation in obese women with depression: effects on metabolic and clinical response」

Non-Patent Document 3

Summary of the Invention

Problems to be Solved by the Invention

[0012] Water-soluble dietary fiber has a low possibility of laxative effect and has an intestinal regulating effect, and is furthermore easy to use in general foods. If water-soluble dietary fiber has a function of improving fatigue and / or mood state, it can contribute to the improvement of the QOL of general consumers. As a result of intensive research, the inventors have discovered an action of reducing fatigue and / or mood state by ingestion of inulin and have completed the present invention.

Means for Solving the Problems

[0013] <2>The composition for improving fatigue and / or mood state according to <1>, wherein the dose of inulin is 4.0 g to 20 g per day. <3>The composition for improving fatigue and / or mood state according to <1> or <2>, wherein the administration or ingestion subject is a healthy subject. ​​​​​​<4> Fatigue improvement is reflected in the VAS scores for "overall fatigue," "mental fatigue," and "physical fatigue." Selected from a group consisting of "feeling of fatigue," "perceived stress," "level of tension," and "irritability." This involves lowering at least one score. In POMS2, improvement in mood state is associated with "Total Mood State" (TMD). This is to lower the score of (od Disturbance). <1> ~ <3> Noi A composition for improving fatigue and / or mood state as described below. <5> The ratio of fructooligosaccharides with a chain length of 5 or less to the total amount of inulin contained in the composition is , less than 50% by weight, <1> ~ <4> Fatigue and / or mood changes described in any of the following: Composition for good use. <6> It has the effect of improving both fatigue and mood. <1> ~ <5> Note in one of the following: A composition for improving fatigue and / or mood. <7> It is a food composition. <1> ~ <6> Fatigue and / or mood changes described in any of the following: Composition for good use. [Effects of the Invention]

[0014] The functional food of this invention uses inulin as an active ingredient and is applicable to food and beverages in general. It is a highly versatile substance with a wide range of applications. Furthermore, the inulin's intestinal regulating effect helps alleviate fatigue. In addition to improving mood, it can also be expected to maintain health and prevent disease. Inulin, a beneficial compound, is found in wheat and plants of the Asteraceae family, and has a long history of being consumed as food. Furthermore, it is highly safe for the human body, there is no need to worry about side effects, and it can be taken continuously over a long period of time. Cut. [Brief explanation of the drawing]

[0015] [Figure 1]This graph shows the changes in mood (anger and hostility) due to POMS in test subjects who ingested 15g of inulin or placebo per day. [Figure 2] This graph shows the changes in mood (tension / anxiety) due to POMS in test subjects who ingested 15g of inulin or placebo per day. [Figure 3] This graph shows the changes in mood state (TMD score) as measured by POMS in test subjects who ingested 15g of inulin or placebo per day. [Figure 4] This graph shows the changes in mood state (fatigue and lethargy) due to POMS in test subjects who ingested 5.0g of inulin or placebo per day. [Figure 5] This graph shows the changes in mood (tension / anxiety) due to POMS in test subjects who ingested 5.0g of inulin or placebo per day. [Figure 6] This graph shows the changes in mood state (vitality-energy) due to POMS in test subjects who ingested 5.0g of inulin or placebo per day. [Figure 7] This graph shows the changes in mood state (TMD score) as measured by POMS in test subjects who ingested 5.0g of inulin or placebo per day. [Figure 8] This graph shows the results of an examination of physical and mental fatigue, as measured by a Visual Analog Scale (VAS), in test subjects who ingested 5.0g of inulin or placebo per day. [Figure 9] This graph shows the results of an examination of physical and mental fatigue, as measured by a Visual Analog Scale (VAS), in test subjects who ingested 5.0g of inulin or placebo per day. [Modes for carrying out the invention]

[0016] (Inulin) In this specification, inulin is defined as GFn(G: glucose, F: fructose, n: fructose). It is a polymer of fructan represented by the number of luctose molecules (n≧2), and is a polymer of sucrose fructan. The tose side has a structure in which two or more D-fructose molecules are dehydrated polymerized via β-(2→1) bonds. It means something that does something. Inulin is usually sold as aggregates with different degrees of polymerization. For example However, inulin derived from plants, although there are some differences depending on the type of plant, has a degree of polymerization The distribution is known to be in the range of approximately 8 to 60, with an average degree of polymerization of around 30. The inulin used in this invention preferably has an average degree of polymerization of 5 to 30. The inulin used in this invention has a low polymer content (inulin with a degree of polymerization of 4 or less). The amount is small, specifically, the proportion of inulin used is 10% or less of the total amount used. This is preferable. The inulin used in this invention is preferable to sugar in terms of solubility and flavor. It is preferable to use a product purified by enzyme treatment. Also, fractal with a chain length of 5 or less. Oligosaccharides and / or oligofructose, which are breakdown products of inulin, in the entire inulin From the viewpoint of maintaining flavor and keeping hygroscopicity low, the proportion should be less than 50% by weight, preferably. 40% by weight or less, more preferably 30% by weight or less, even more preferably 20% by weight or less, Most preferably, it is 10% by weight or less.

[0017] In the present invention, the fructooligosaccharide component with a chain length of 5 or less in the total dose of inulin The dosage is preferably 5.0g or less per day, more preferably 4.5g or less, and 4.0g or less. The lower the value, the more preferably the 3.6g or less, and the most preferably the 3.0g or less.

[0018] The inulin used in this invention is extracted from plants, chemically synthesized, or fermented. It is not particularly limited to those produced by a specific agent, and is not limited to those of any origin. It can exert an effect of improving intestinal function. When focusing on the degree of polymerization of inulin, The properties differ depending on the size; low polymers (especially those with a degree of polymerization of 4 or less) exhibit a sweet taste, while high polymers ( In particular, those with a polymerization degree of 30 or higher have the characteristic of being poorly soluble in water. Therefore, the distribution of the degree of polymerization is a characteristic of processing. It affects the properties, taste, and texture. Therefore, it is preferable that the average degree of polymerization is 5 to 30. The low polymer content is low, specifically, 5% by weight or less based on the inulin used. It is desirable to do so.

[0019] The inulin used in this invention can be analyzed by known methods. For example, it can be measured as fructan. One method is the AOAC999.03 method, which involves treating food with enzymes and measuring the spectral photometric value. This is a method for measuring fructan inside. Additionally, the AOAC997.08 method uses yeast to measure inulin. By processing the food and analyzing it using cation exchange chromatography, fructans in the food are detected. This is a method for measuring [something]. When measuring as water-soluble dietary fiber, in addition, enzyme HPLC is used. The law can also be used. Furthermore, the degree of polymerization of inulin can also be analyzed using known methods. For example, A In the OAC997.03 method, glucose and fructose are measured before and after enzymatic treatment. The average degree of polymerization can be obtained by measuring the quantitative ratio. GPC method (Gel Permeation Chromatography) GFP, also known as SEC or GFP, is widely used as a method for measuring the molecular weight of polymers. It is included. This method can also be used to measure the molecular weight of inulin, i.e., the degree of polymerization. Furthermore, methods using light scattering, nuclear magnetic resonance (NMR), viscosity, vapor pressure, and freezing point depression are also used. The degree of polymerization can be measured using various methods, including those employing physical phenomena.

[0020] The fatigue and / or mood improvement composition of the present invention is provided within the limits that do not impair the effects of the present invention. It contains dietary fiber other than inulin, such as indigestible dextrin and polydextrose. It can be included, but it is not necessary to include it.

[0021] (Daily dose) In the present invention, the daily dose or intake of inulin is such that the effects of the present invention can be obtained. While not strictly limited, it is preferably 4.0g or more and 20g or less. Lower limit and upper limit For example, 5.0g, 6.0g, 7.0g, 8.0g, 9.0g, 10g, 11g, 12 Choose one of the following amounts: g, 13g, 14g, 15g, 16g, 17g, or 18g. They can be hired. The above dosage is the daily dose, and it can be taken in several doses, for example, in the morning, noon, and evening. While this is also acceptable, it is preferable to ingest or administer it in a single dose. The duration of administration or ingestion is not particularly limited. It is not strictly necessary, but preferably it should be 4 weeks or longer.

[0022] (subject) The fatigue and / or mood improvement composition of the present invention is administered to mammals, particularly humans, or It is intended to be ingested. Target groups include, for example, minors under 20 years old, adults, and those 65 years of age and older. It can be administered to the elderly, those under 65 years of age, etc. The target population includes healthy individuals and The subject may also be someone suffering from a disease (for example, a mental illness such as depression, or obesity), It is preferable that the subjects be healthy. Healthy subjects are those with mental illnesses or obesity, etc. This refers to individuals who do not have chronic illnesses affecting their mental or physical health.

[0023] (Fatigue relief) Fatigue is a sign that the body needs rest to maintain homeostasis, and is a sign of excessive activity. This is important to prevent exhaustion and illness caused by these factors. In this specification, "fatigue" is defined in accordance with the definition established by the Japanese Society for Fatigue Research. That is, "Fatigue" is defined as "a unique feeling of discomfort and rest caused by excessive physical and mental activity or illness." It means "a state of reduced physical activity accompanied by a desire for nourishment." Therefore, in this specification, "fatigue" This includes "physical fatigue," which is a type of fatigue where fatigue gradually accumulates in the body and the condition progresses, and Psychological stress from interpersonal relationships and the environment can cause mental fatigue, accompanied by mental distress and physical symptoms. This also includes "mental fatigue," which is a form of mental exhaustion.

[0024] (VAS) The Japanese Society for Fatigue Research states in its "Guidelines for Clinical Evaluation of Fatigue" that "methods for evaluating fatigue" It has been indicated that "VAS testing is useful for this purpose." Therefore, in this embodiment, the main fatigue Observational evaluation is based on the fatigue sensation indicated in the Japanese Society for Fatigue Research's Clinical Evaluation Guidelines for Anti-Fatigue. The VAS (Visual Analogue Scale) was used. Specifically, A On sheet 4, a 100mm line is drawn horizontally, with "None at all" at the left end and "Most present" at the right end. In this case, for each item, indicate where the current state is located by drawing a "|" on the line, and from the starting point... The distance (mm) to the "|" was used as the score for that item. For items related to the body and fatigue, "All "Physical fatigue," "Mental fatigue," "Physical exhaustion," "Perceived stress," "Level of tension" "Sleepiness", "Boredom", "Motivation", "Hunger", "Thirst", "Irritability", They rated the "refreshing feeling" highly. In this invention, fatigue improvement is achieved by measuring "overall fatigue" before and after administration of the composition using a VAS test. "Feeling," "mental fatigue," "physical fatigue," "perceived stress," "tension level," "sleepiness" "Boring level," "Motivation," "Hunger," "Thirst," "Irritability," and "Refreshment" The evaluation is based on whether or not at least one score selected from the group consisting of "feeling" improves. It is possible. In this specification, "fatigue improvement" preferably means "overall fatigue" before and after administration of the composition. "Feeling," "mental fatigue," "physical fatigue," "perceived stress," "level of tension," and " This involves reducing the score of at least one item selected from the group consisting of "irritability." More preferably, "overall fatigue," "mental fatigue," "physical fatigue," "perceived fatigue" The goal is to reduce all scores related to "stress," "tension," and "irritability."

[0025] (Improvement of mood) In this specification, "mood state" refers to the AH score in the Affect Profile Scale (POMS). (Anger-Hostility), CB (Confusion-Bewilderment), DD (Depression-Depression), FI (Fatigue-Apathy) ), TA (Tension-Anxiety), VA (Vitality-Energy), F (Friendliness) - each of 7 subscales with 5 items. It consists of a total of 35 items on a 5-point rating scale (score range 0-4 points), and includes a negative scale (AH). The score obtained is calculated by subtracting the score of VA (a positive measure) from the total score of CB, DD, FI, TA. The "Total Mood Disturbance" (TMD) is a comprehensive mood state. It can be evaluated using a score.

[0026] (POMS2) In this embodiment, the Japanese version of the POMS, consisting of 65 questions, is used to measure mood state. (Profile of mood states) was used. The Profile of Affectiveness (POMS) is a useful tool for understanding the emotional functioning of adults. This is a test that covers a wide range of mood states. This study includes the Japanese version of Profile of Mo The abbreviated version of od States (hereinafter referred to as POMS2) was used. Specifically, AH (Anger-Hostiles) ), CB (Confusion-Bewilderment), DD (Depression-Depression), FI (Fatigue-Apathy), TA (Tension) The assessment consists of 7 subscales: Zhang (anxiety), VA (vitality), and F (friendliness), each with 5 items, for a total of 35 items. It consists of a 5-point rating scale (score range 0-4 points), and includes negative scales (AH, CB, DD). The score for VA, a positive measure, is subtracted from the total score of FI, TA, and the score for negative measures. "Total Mood Distension" (TMD) is a term used to describe a state of mind. The score is being calculated. In this invention, improvement in mood state is defined as an improvement in the TMD (Total Mood Disorder) score. It can be evaluated based on whether or not it occurs. In other words, in this specification, "improvement of mood state" means Preferably, before and after administration of the composition, AH (anger-hostility), CB (confusion-embarrassment), and DD (suppression) are observed. Depression (downcast), FI (fatigue-apathy), TA (tension-anxiety), VA (vitality-energy), By lowering the score of at least one selected from the group consisting of F (friendly) Yes, and more preferably, "Total Mood Disorder" (TMD). It is about lowering the mood score, which is represented by a score of (rbance).

[0027] The present invention's composition for improving fatigue and / or mood state preferably improves fatigue and mood state. It has both beneficial and detrimental effects.

[0028] (Food composition) When the present invention is a composition for improving fatigue and / or mood, it is a food composition (hereinafter referred to as the present invention). The food composition of the present invention (sometimes referred to as the food composition of the present invention) is, for example, a carbonated beverage. This includes various fruit juices, fruit juice beverages and fruit juice-containing soft drinks, fruit pulp beverages and fruit juice beverages with fruit pieces, and various vegetables. Vegetable-based beverages, soy milk and soy milk drinks, coffee beverages, tea beverages, powdered beverages, concentrated beverages, sports General beverages such as sodas and nutritional drinks, as well as alcoholic beverages containing the aforementioned beverages; instant noodles Cup noodles, retort pouches and prepared foods, canned prepared foods, microwaveable foods, instant miso soup and clear soups Instant foods such as canned soups and freeze-dried foods; confectionery items; bread, macaroni, etc. Wheat flour products such as pagent, noodles, cake mix, fried chicken batter, breadcrumbs, and dumpling wrappers. Caramel candy, chewing gum, chocolate, cookies and biscuits Cakes and pies, snacks and crackers, Japanese sweets, rice crackers and bean snacks, dessert sweets, etc. Confectionery; soy sauce, miso, sauces, tomato-based seasonings, mirin, vinegars, sweeteners, etc. Basic seasonings; flavorings, cooking mixes, curry bases, sauces, dressings, etc. Mixed seasonings and foods such as noodle soup bases and spices; butter, margarine, and mayonnaise. Oils and fats such as vegetable oils; milk and processed milk, milk beverages, yogurts, lactic acid bacteria beverages, cheese, etc. Milk creams, powdered milk, creams and other dairy products; frozen raw materials, semi-prepared frozen foods Products, frozen foods such as pre-cooked frozen foods, canned seafood, canned fruits and pastes, fish ham • Processed seafood products such as sausages, fish paste products, seafood delicacies, dried seafood products, and preserved seafood; livestock Canned goods and pastes, canned meat, canned fruit, jams and marmalades, pickles and boiled beans Dried agricultural products, processed agricultural products such as cereals (grain products); baby food, furikake (rice seasoning) Examples include commercially available foods such as instant rice seasoning; liquid preparations; tablets; capsules; granules; powders; and fine granules. It is possible.

[0029] The food composition of the present invention optionally contains antioxidants, flavorings, acidulants, colorings, emulsifiers, and preservatives. Preservatives, seasonings, sweeteners, spices, pH adjusters, stabilizers, vegetable oils, animal oils, sugars and sugar alcohols Acids, vitamins, organic acids, fruit extracts, vegetable extracts, grains, legumes, vegetables, meat, Additives and ingredients such as seafood can be blended individually or in combination of two or more types. The proportions of these materials and additives should be determined appropriately within a range that does not impair the purpose of the present invention. It is possible.

[0030] The food composition of the present invention is a molded container (PET) mainly composed of polyethylene terephthalate. Bottles, metal cans, paper containers combined with metal foil or plastic film, aluminum pouches Pouches, plastic containers, vinyl containers, PTP (Press-Through Packaging), etc. ) can be provided in packaging, and filled into ordinary packaging containers such as glass bottles and other bottles, There are no particular limitations regarding capacity.

[0031] The food compositions of the present invention include functional foods (beverages) and health foods (beverages). In the detailed document, "health food (beverage)" means something that has some effect on health, or something that has some effect on health. It means food or beverages that can be expected to produce the above-mentioned "Functional Food (Beverage)" Among "health foods (beverages)," the various biological regulatory functions mentioned above (i.e., the digestive system, the circulatory system) The regulatory functions of physiological systems such as the autonomic nervous system, endocrine system, immune system, or nervous system are fully expressed. This refers to food or beverages that are designed and processed to be used in this way.

[0032] The amount of inulin to be incorporated into the food composition is within a range that does not impair the effects of the present invention. There are no restrictions, and according to food composition standards, it is usually 1-20% by weight, 1-10% by weight, or 3-7% by weight. It is a percentage.

[0033] The present invention's composition for improving fatigue and / or mood states includes, for example, "anxiety, depression, "to reduce feelings of confusion," "to reduce the decline in vitality and energy," "to reduce the decline in vitality and energy" "Increase," "Alleviate mental stress," "Improve a depressed mood," "Relieves temporary mental stress and fatigue," "Makes you feel more energetic," "Fatigue "To reduce the feeling of fatigue," "To reduce the feeling of physical fatigue that occurs in daily life," "To reduce fatigue upon waking up" "To reduce," "To reduce work stress and fatigue caused by desk work," "To reduce daily life and It can display a function that "reduces fatigue after exercise" or a function that can be considered equivalent to this. The above "display" includes everything that informs consumers of the aforementioned functions, and the display is for the following: , the composition itself for improving fatigue and / or mood, packaging, containers, catalogs, brochures, and This applies regardless of the medium, such as an internet homepage. [Examples]

[0034] The present invention will be further described below with reference to manufacturing examples and embodiments. However, the present invention is... This is not limited to the above. Unless otherwise specified in this specification, % refers to weight %. This shows that the inulin used in the examples has an average degree of polymerization of 5 to 30 and is low in weight. The content of the compound (inulin with a degree of polymerization of 4 or less) is 10% or less of the total amount of inulin used. These are oligo-fructooligosaccharides with a chain length of 5 or less, and / or oligo-fructooligosaccharides that are degradation products of inulin. The proportion of lactose in the total inulin is 10% by weight or less, based on the total amount of inulin used. It is below.

[0035] Manufacturing Example 1: Green Juice with Inulin A mixture of 50% young barley grass, 48.9% inulin, 0.1% lactic acid bacteria, and 1.0% wild grass fermentation extract. This yielded inulin-containing green juice powder. 8g of inulin-containing green juice powder was dissolved in 150ml of cold water. By dispersing it, it becomes a green juice containing 3.9g of inulin. The inulin content reduces bitterness and astringency. This can mask the unique taste of green juice, making it easier to drink. It has been shown that this may improve mental health, and the effects of taking it together with inulin are also shown. Results can be expected.

[0036] Manufacturing Example 2: Cocoa Beverage Milk protein 49%, inulin 23%, cocoa powder 14%, skim milk powder 11.5%, emulsified A mixture of 1.1% of an ingredient, 0.6% of thickening polysaccharides, 0.6% of flavoring, and 0.3% of sweeteners, containing inulin. I obtained cocoa drink powder. I added 25g of this inulin-containing cocoa drink powder to 150ml of hot water. By dissolving and dispersing it, it becomes a cocoa beverage containing 5.75g of inulin. As a result, even with less sugar, the body is improved, the texture becomes smoother, and there is a milky flavor. Furthermore, by reducing the protein odor, it became a beverage with a clean aftertaste. Theobromine is thought to be related to serotonin, and is believed to have a relaxing effect. It has been shown that simultaneous administration with inulin can be expected to improve mental health.

[0037] Manufacturing Example 3: Yogurt Sauce Powder Powdered sugar 47-48%, inulin 41-42%, citric acid 1-1.2%, fruit juice powder 6-9% By mixing 1.8% of the ingredients, 1.8% of the flavoring, and 0-1.2% of the coloring, an inulin-containing fruit-flavored sauce is created. I got some Uda. I added about 10g of this inulin-containing fruit-flavored sauce powder to commercially available yogurt. By sprinkling it on, you can enjoy fruit-flavored yogurt while also consuming inulin. Yes, it's possible. Adding inulin improves the body and makes the yogurt richer. By changing the type of uder and adjusting the formula accordingly, various flavored powders can be obtained. It is possible. Studies have shown that consuming certain lactic acid bacteria may improve mental health. Therefore, by combining it with yogurt made with specific lactic acid bacteria, inulin can be consumed simultaneously. The effects of taking it can be expected.

[0038] Manufacturing Example 4: Inulin-containing cheese powder Cheese extract powder 5.8%, inulin 75.4%, milk protein or skim milk powder 18.8% By mixing % of the ingredients, we obtained a cheese-flavored powder containing inulin. This powder is ideal for foods like pasta that are low in fiber. Even in meals where you tend to add extra ingredients, you can consume dietary fiber without compromising the taste or texture. Furthermore, by changing the extract powder to butter extract or other ingredients, it can be adapted to a variety of dishes. Adding nurin masks off-flavors and enhances the richness of the flavor.

[0039] [Example 1. Verification of Function] This study will investigate the effects of inulin intake on physical and mental fatigue and mucosal immunity in healthy adults. Therefore, a randomized placebo-versus-pattern study was conducted targeting approximately 30-50 men and women who are generally considered healthy. A double-blind, parallel-group comparative study was conducted. Participants received either inulin or placebo (maltodex). Trin) was taken in the prescribed amount daily. VAS and POMS were measured before intake and 4-6 weeks after intake. Which questionnaire tests were administered?

[0040] (Test 1) Of the 30 test subjects who were given 15g of inulin or placebo per day for 6 weeks, The analysis included 27 participants who had a consumption rate of 80% or higher and who completed measurements of all items before and after the experiment. Regarding the comparison between the test group (12 people) and the placebo group (15 people), mood states were assessed using POMS. We investigated this matter. The results are shown in Figures 1-3.

[0041] In the group that ingested inulin, AH (anger-hostility), TA (tension-anxiety), and TM were observed. A significant decrease in the D score was observed when comparing the scores before and after the study.

[0042] (Exam 2) Fifty test subjects were given either inulin or placebo at a daily dose of 5.0g for four weeks. The analysis included 48 participants who had a consumption rate of 80% or higher and who completed measurements of all items before and after the experiment. The comparison between the test group (25 people) and the placebo group (23 people) was conducted using the POMS (Prescription of Mood State). We investigated this matter. The results are shown in Figures 4-7.

[0043] In the test sample group, FI (Fatigue-Apathy), TA (Tension-Anxiety), and TMD (Total Disorder) were observed. A significant decrease in mood and a significant increase in VA (vitality - energy) were observed. Furthermore, intergroup comparisons were also performed. Compared to the placebo group, the test group showed significantly higher VA (vitality - energy) scores.

[0044] (Exam 3) In the subjects of Study 2, we examined mental and physical fatigue as measured by a Visual Analog Scale (VAS). The results are shown in Figures 8-9. This will be shown.

[0045] In the group comparison using before-and-after differences, the test group showed "overall fatigue" and " "Mental fatigue," "physical fatigue," "perceived stress," "level of tension," and "irritability." A significantly low value was observed for "feeling." [Industrial applicability]

[0046] The food product having the function of improving fatigue and / or mood state in this invention contains inulin as an active ingredient. This makes it a highly versatile substance that can be widely applied to food and beverages in general. Due to its intestinal regulating effect, it helps maintain health and prevent disease, in addition to improving fatigue and / or mood. It's promising.

Claims

1. A composition for improving fatigue and / or mood, comprising inulin as an active ingredient, Fatigue improvement is defined as a decrease in at least one score selected from the group consisting of "overall fatigue," "mental fatigue," "physical fatigue," "perceived stress," "tension," and "irritability" on the VAS. The fatigue and / or mood-improving composition wherein the improvement of mood state is a reduction in at least one score selected from the group consisting of AH (anger-hostility), CB (confusion-embarrassment), DD (depression-dejection), FI (fatigue-apathy), TA (tension-anxiety), VA (vitality-energy), and F (friendliness) in the POMS2.

2. The composition for improving fatigue and / or mood state according to claim 1, wherein the dose of inulin is 4.0 g to 20 g per day.

3. The fatigue and / or mood improvement composition according to claim 1 or 2, wherein the target of administration or intake is a healthy subject.

4. A composition for improving fatigue and / or mood state according to any one of claims 1 to 3, wherein the ratio of fructooligosaccharides with a chain length of 5 or less to the total amount of inulin contained in the composition is less than 50% by weight.

5. A composition for improving fatigue and / or mood, according to any one of claims 1 to 4, which has the effect of improving both fatigue and mood.

6. It is a food composition. A composition for improving fatigue and / or mood state according to any one of claims 1 to 5.

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