Medical systems and devices for lifting tissues

Abstract

The medical system includes an insertion device having a working channel, a first medical device configured to be positioned within the working channel of the insertion device, and a second medical device configured to be positioned within the working channel of the insertion device. The first medical device includes a handle, a control element extending from the handle, a removable portion, a helical coil coupled to the removable portion, and a loop. The removable portion is detachably coupled to the distal portion of the control element. A first portion of the loop is coupled to the removable portion, and a second portion of the loop extends radially away from the removable portion. The second medical device is configured to receive the second portion of the loop. The second medical device is configured to couple the second portion of the loop to a portion of the treatment site.

Description

Technical Field

[0001] The present disclosure generally relates to medical systems, devices, and related methods that can be used to treat a subject. More particularly, at least some embodiments of the present disclosure relate to systems, devices, and related methods for lifting tissue.

Background Art

[0002] The walls of organs often consist of several layers such as the mucosa (surface layer), submucosa, muscular layer (muscle layer), and serosa (connective tissue layer). In gastrointestinal cancer, colon cancer, and esophageal cancer, lesions or cancerous tumors may form along the mucosa and often spread into the lumen of the organ. Conventionally, this condition has been treated by excising a portion of the wall of the affected organ. However, this treatment can cause discomfort to the patient and / or pose a health risk.

[0003] Physicians have adopted minimally invasive techniques such as endoscopic procedures like endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD). The EMR method is typically used for the removal of small cancerous or abnormal tissues (e.g., polyps), and the ESD method is typically used for the en bloc removal of large cancerous or abnormal tissues (e.g., lesions). These procedures are generally performed using an endoscope and other instruments. During these procedures, the endoscope can be passed through a percutaneous incision, through the throat, or guided through the rectum to reach the tissue targeted for resection or incision, such tissue having an abnormality such as a lesion or cancerous tumor in the affected organ. The abnormality is usually identified and marked.

[0004] Next, the mucosal layer containing the abnormality is separated from the underlying tissue layer using a medical instrument extending through the working channel or lumen of the endoscope. The abnormality is then removed using the same or a different medical instrument. Conventionally, tissue is removed using a cutting device such as a wire loop or knife, which can be adapted for electrocautery. The excised tissue can then be extracted for examination or disposal using a tissue removal device such as a gripper or other device for holding the tissue. Both cutting and tissue removal devices often require applying a large tensile or lifting force to the tissue during the procedure, and such lifting force can be limited by conventional devices. With conventional tissue cutting and gripping devices, the limited lifting force can increase procedure time, cause injury to the patient, or lead to other procedural complications.

[0005] The systems, devices, and methods of this disclosure can correct some of the defects described above or address other aspects of the art. [Overview of the project]

[0006] Examples of this disclosure relate, in particular, to systems, devices, and methods for performing one or more medical procedures using medical devices. Specifically, this disclosure includes medical systems and devices comprising an end-effector, and methods of using the same (e.g., a method of delivering the end-effector to a patient's treatment site to, for example, lift tissue). Each of the examples disclosed herein may include one or more features described in relation to any of the other examples disclosed.

[0007] In one embodiment, the medical system may comprise an insertion device having a working channel, a first medical device, and a second medical device. The first medical device may be configured to be positioned within the working channel of the insertion device. The first medical device may have a handle, a control element extending from the handle, a removable portion, a helical coil coupled to the removable portion, and a loop. The removable portion may be detachably coupled to the distal portion of the control element. The helical coil may be coupled to the removable portion. The loop may include a first portion and a second portion. The first portion of the loop may be coupled to the removable portion. The second portion of the loop may extend radially away from the removable portion. The second medical device may be configured to be positioned within the working channel of the insertion device. The second medical device may be configured to receive the second portion of the loop. The second medical device may be configured to couple the second portion of the loop to a portion of the treatment site.

[0008] The medical system may include one or more of the following features: The first medical device may further include a coupler. The coupler may include a first part which is coupled to or is part of the distal portion of a control element. The coupler may include a second part which is coupled to or is part of the proximal portion of a removable portion. The first and second parts may be configured to releasably couple the removable portion to the control element. The first part of the coupler may be configured to overlap at least a portion of the second part of the coupler.

[0009] In some configurations, the first contact surface of the first part may be in contact with the second contact surface of the second part. The first contact surface of the first part may have a shape complementary to the contact surface of the second part. In some embodiments, a portion of the first part of the coupler may be magnetic. A portion of the second part of the coupler may have magnetism of the opposite polarity to that of the portion of the first part.

[0010] In some embodiments, a portion of the first part of the coupler may include an electromagnet, and a portion of the second part of the coupler may be made of a magnetic material. In some configurations, rotation of the helical coil in a first direction may be configured to connect the distal portion to the tissue wall. Rotation of the helical coil in a second direction may be configured to disconnect the helical coil from the tissue wall. The helical coil may include multiple windings. Adjacent windings of a first portion of the multiple windings may be separated by a first distance. Adjacent windings of a second portion of the multiple windings may be separated by a second distance. Adjacent windings of a third portion of the multiple windings may be separated by a third distance. In some embodiments, the third distance may be greater than the second distance, and the second distance may be greater than the first distance.

[0011] In some embodiments, the handle may include a stationary body, a first movable body, and a second movable body. The first movable body can control the axial movement of the distal portion of the control element. The second movable body can control the rotational movement of the distal portion of the control element. The stationary body may include a first indicator for identifying the axial movement of the helical coil. The second movable body may include a second indicator for identifying the rotational movement of the helical coil.

[0012] In some configurations, the second medical device may include a clip. The second portion of the loop may, in some configurations, be made of a resilient material. The medical system may further include, in some configurations, a third medical device configured to be positioned within the working channel of the insertion device. The third medical device may be configured to cut tissue.

[0013] In some configurations, the first and second parts of the coupler may be joined by an adhesive material. In the first configuration, the material may be located within a sheath extending from the handle. In the second configuration, the material may not be covered by a sheath. In the second configuration, the material may degrade, causing the bond between the first and second parts of the coupler to break.

[0014] According to an alternative embodiment, the medical device may include a handle, a control element, a removable part, a helical coil, and a loop. The control element may extend from the handle. The removable part may be detachably coupled to the distal part of the control element. The helical coil may be coupled to the removable part. The loop may have a first part and a second part. The first part of the loop may be coupled to the removable part. The second part of the loop may extend radially outward from the removable part.

[0015] The medical device may include one or more of the following features. In some configurations, the first medical device may further include a coupler. The coupler may include a first part which is coupled to or is part of the distal portion of a control element. The coupler may include a second part which is coupled to or is part of the proximal portion of a removable part. The first and second parts may be configured to releasably couple the removable part to the control element. Part of the first part of the coupler may be a magnet, and part of the second part of the coupler may be a magnetic material.

[0016] In another embodiment, the method may include delivering an insertion device and a first medical device to a treatment site through a lumen. The first medical device may be configured to be positioned within a working channel of the insertion device. The first medical device may include a handle, a control element, a removable portion, a helical coil, and a loop. The control element may extend from the handle. The removable portion may be detachably coupled to the distal portion of the control element. The helical coil may be coupled to the removable portion. A first portion of the loop may be coupled to the removable portion, and the second medical device may be configured to receive a second portion of the loop.

[0017] The method may further include coupling a helical coil to the wall of a lumen, detaching a removable portion from a control element, and delivering a second medical device. The second medical device may be configured to be positioned within a working channel of the insertion device. The second medical device may include a removable clip. The method may further include attaching the removable clip to a loop, coupling the removable clip to the treatment site, delivering a third medical device, and using the third medical device to excise at least a portion of the treatment site. The third medical device may be configured to be positioned within a working channel of the insertion device.

[0018] After delivering a third medical device and partially excising the treatment site using the third medical device, the method may further include delivering a first medical device, connecting the first medical device to a removable portion including a helical coil, and repositioning the removable portion. The method may further include delivering a third medical device and excising at least a second portion of the treatment site using the third medical device.

[0019] Any of the examples described herein may have any combination of these features.

Brief Description of the Drawings

[0020] The accompanying drawings incorporated herein and constituting a part of this specification illustrate exemplary aspects of the present disclosure and serve to explain the principles of the present disclosure together with the description. [Figure 1A] FIG. 1A is a perspective view of a medical device including a distal portion in a first configuration or a combined configuration according to an aspect of the present disclosure. [Figure 1B] FIG. 1B is a perspective view of the distal portion of a medical device in a second configuration according to an aspect of the present disclosure. [Figure 2A] FIGS. 2A - 2E are perspective views of the distal portion of an exemplary medical system in various states during operation according to an aspect of the present disclosure. [Figure 2B] FIGS. 2A - 2E are perspective views of the distal portion of an exemplary medical system in various states during operation according to an aspect of the present disclosure. [Figure 2C] FIGS. 2A - 2E are perspective views of the distal portion of an exemplary medical system in various states during operation according to an aspect of the present disclosure. [Figure 2D] FIGS. 2A - 2E are perspective views of the distal portion of an exemplary medical system in various states during operation according to an aspect of the present disclosure. [Figure 2E] FIGS. 2A - 2E are perspective views of the distal portion of an exemplary medical system in various states during operation according to an aspect of the present disclosure. [Figure 3] FIG. 3 is a flowchart of an exemplary method according to an aspect of the present disclosure.

Modes for Carrying Out the Invention

[0021] Here, aspects of the present disclosure are referred to in detail, and examples thereof are shown in the accompanying drawings. As far as possible, the same or similar reference numerals are used throughout the drawings to refer to the same or similar parts. The term "distal" refers to the part that is furthest from the user when the device is introduced into a subject (e.g., a patient). In contrast, the term "proximal" refers to the part that is closest to the user when the device is placed on the subject.

[0022] Both the foregoing general description and the following detailed description are exemplary and explanatory only and do not limit the claimed features. As used herein, the terms "comprise," "comprising," "have," "including," or other variations thereof are intended to cover non-exclusive inclusion such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. In the present disclosure, relative terms such as "about," "substantially," "generally," and "approximately" are used to indicate possible variations of ±10% in the recited values or characteristics.

[0023] The treatment site is described herein as being within the gastrointestinal tract of the subject, but the present disclosure is not so limited, and the treatment site may be any internal lumen, organ, cavity, or other tissue within the subject. In addition, although an endoscope is referred to herein, any medical device having a working channel or lumen extending from the proximal end to the distal end, such as a ureteroscope, duodenoscope, gastroscope, endoscopic ultrasound ("EUS") scope, colonoscope, bronchoscope, laparoscope, arthroscope, cystoscope, aspiration scope, sheath, or catheter, is understood to be encompassed by the present disclosure.

[0024] Embodiments of this disclosure may address one or more limitations in the art. However, the scope of this disclosure is defined by the appended claims, not by the ability to solve a particular problem. This disclosure relates, among other things, to systems, devices, and related methods for medical devices for lifting tissue.

[0025] Figure 1A is a perspective view of a medical device 100 having a handle 101 and a distal portion 102 in a first configuration (e.g., coupled or attached). Figure 1B shows the distal portion 102 of the medical device 100 in a second configuration (e.g., uncoupled or detached). One or more portions of the handle 101 may be movable or operable to control various aspects of the distal portion 102. One or more portions of the distal portion 102 may be movable to facilitate, for example, coupling and / or detaching the distal portion 102 to tissue and / or detaching the distal portion 102 from the medical device 100. The distal portion 102 is shown in detail within circle A in Figure 1A.

[0026] Referring to Figure 1A, the handle 101 may include a stationary body 104 and a first movable body or first actuator 106. The movement of the first movable body 106 relative to the stationary body 104 can control the movement of a portion of the distal portion 102 (e.g., extension or retraction). For example, one or more control elements 108 may be coupled to the first movable body 106 and a portion of the distal portion 102, so that the first movable body 106 can control the movement of one or more portions of the distal portion 102 (e.g., axial movement such as extension or retraction). The control elements 108 may be made of any rigid or semi-rigid material, such as metal, polymer, or metal-polymer composite. The control elements 108 may be formed by a coil, braid, tube, sheath, etc. The control element 108 may be bonded (e.g., directly or indirectly) to the first movable body 106 (e.g., directly or indirectly) or otherwise connected by, for example, adhesive, mechanical fitting, snap fitting, press-fit, welding (e.g., laser welding), or any other bonding technique commonly known in the art. In some embodiments, multiple control elements 108 are used. In such embodiments, each of the multiple control elements 108 is formed of the same or different material and / or bonded to the distal portion 102 and the first movable body 106 or otherwise connected by the same or different bonding technique.

[0027] The outer sheath 110 may be bonded (e.g., directly or indirectly) to the stationary distal handle portion 111 of the handle 101 (e.g., directly or indirectly) or otherwise connected by, for example, adhesive, mechanical fitting, snap fitting, press-fit, welding (e.g., laser welding), or any other bonding technique commonly known in the art. The control element 108 may be movable within the outer sheath 110, for example, within the lumen 113. The proximal portion of the stationary body 104 may include, for example, a finger ring 112 for receiving the user's thumb.

[0028] The first movable body 106 may at least partially surround a portion of the stationary body 104, and a portion of the first movable body 106 may at least partially extend into the handle slot 114. The handle slot 114 may extend longitudinally through at least a portion of the stationary body 104 of the handle 101. In some embodiments, although not shown, the handle 101 may include one or more biasing elements (e.g., one or more springs) such that the proximal movement of the first movable body 106 relative to the stationary body 104 is biased distally. In these embodiments, when the user releases proximal pressure or force on the first movable body 106, one or more biasing elements can bias the first movable body 106 distally. Alternatively, one or more biasing elements (e.g., one or more springs) may bias the first movable body 106 proximal. In these embodiments, when the user releases distal pressure or force on the first movable body 106, one or more biasing elements can bias the first movable body 106 in the proximal direction.

[0029] The first movable body 106 may include, for example, one or more smaller diameter sections or grooves 106A between the proximal ridge 106B and the distal ridge 106C, which may help facilitate the user's grip of the first movable body 106. For example, the user may position the first movable body 106 between two fingers such that the user's fingers are positioned within the grooves 106A. Thus, the movement of the user's fingers (i.e., relative to the user's thumb in the ring 112) controls the position of the first movable body 106 relative to the stationary body 104, and therefore controls the movement of the control element 108 and / or one or more parts of the distal portion 102.

[0030] The stationary body 104 may include one or more visual or physical indicators 116. The indicators 116 can physically or visually indicate the operation or extension of one or more parts of the distal portion 102. For example, when the first movable body 106 is advanced distally relative to the stationary body 104 within the handle slot 114, and thus acts on one or more parts of the distal portion 102, the first movable body 106 may have to, for example, go over the indicators 116. The indicators 116 can inform the user (for example, via tactile signals or feedback, or via visual signals, etc.) that the distal portion 102 is in an actuated or extended position. The indicators 116 may be on one side of the handle 101, or on two opposing sides of the handle 101 (for example, on the opposite side of the indicators 116 as shown in Figure 1A). The indicators 116 may be bumps, cantilevered projections, recesses, ridges, or any combination thereof. For example, the indicator 116 on one side of the handle 101 may be a bump, and the indicator 116 on the opposite side of the handle 101 may be a cantilevered projection. Many other combinations are possible. Additionally or alternatively, the user can use one or more markings or other visual indicators on the handle 101 (e.g., on the stationary body 104 and / or the first movable body 106) to determine the status, position, operating state, etc., of one or more parts of the distal portion 102.

[0031] The handle 101 may further include a second movable body or a second actuator 118. For example, the movement of the second movable body 118 can control the movement (e.g., rotation) of the control element 108, and thus control one or more parts of the distal portion 102. For example, the control element 108 can be directly or indirectly coupled to the second movable body 118 by means of adhesive, mechanical fitting, snap fitting, press fitting, welding (e.g., laser welding), or any other bonding technique commonly known in the art.

[0032] The second movable body 118 may be positioned on the distal portion of the handle 101. For example, the second movable body 118 may be positioned distally on the stationary body 104 relative to the first movable body 106. Additionally or alternatively, the second movable body 118 may be located between the stationary body 104 and the distal handle portion 111 of the handle 101. The distal handle portion 111 and / or the second movable body 118 may include, for example, one or more ridges or indentations to facilitate the user's grip on each portion of the handle 101.

[0033] The distal handle portion 111 and / or the second movable body 118 may additionally or alternatively include one or more visual or physical indicators, for example, two visual or physical indicators 120A and 120B. For example, indicator 120A may be located on the second movable body 118, and indicator 120B may be located on the distal handle portion 111. Indicators 120A and / or indicator 120B may include one or more of the features of the indicator 116 described above.

[0034] Indicators 120A and 120B can identify or indicate the amount and / or direction of rotational movement of a part of the distal portion 102, such as a helical coil 130. For example, the distance or spacing between indicator 120A on the distal handle portion 111 and indicator 120B on the second movable body 118 may indicate the rotational movement of the helical coil 130. For example, when indicator 120A on the distal handle portion 111 and indicator 120B on the second movable body 118 are aligned, the helical coil 130 is not rotating. Similarly, if indicator 120A on the distal handle portion 111 and indicator 120B on the second movable body 118 are not aligned or are misaligned, the helical coil 130 is rotating (e.g., clockwise or counterclockwise). For example, when rotated clockwise, the helical coil 130 is screwed into the tissue, and when rotated counterclockwise, the helical coil 130 is screwed out of the tissue, and vice versa.

[0035] Although not shown, the handle 101 may include one or more locks so that, for example, the first movable body 106 and / or the second movable body 118 can be locked in place. For example, the indicator 116 may include one or more indentations and / or projections so that when the first movable body 106 is advanced distally beyond the indicator 116, the first movable body 106 is locked in place and / or cannot be retracted proximally without again going over the indicator 116. The second movable body 118 may additionally or alternatively include a lock or locking mechanism (not shown) for, for example, preventing rotational movement of the second movable body 118. The lock or locking mechanism may include, for example, a ratchet mechanism having a ratchet and a pawl, or any other lock or locking mechanism commonly known in the art. The locking or fixing mechanism may, alternatively or additionally, include one or more biasing features to assist in controlling, for example, the movement or rotation of the first movable body 106 and / or the second movable body 118.

[0036] Although not shown, in some embodiments, the handle 101 may not include a first movable body 106 and / or a second movable body 118. In such embodiments, the medical device 100 may not include an external sheath 110. Thus, the control element 108 may be fixedly coupled to the handle 101 (e.g., directly or indirectly). In this configuration, the distal portion 102 may be rotated, for example, by rotating the entire handle 101. Rotation of the handle 101 then rotates the control element 108 and the distal portion 102, which includes the helical coil 130. For example, rotating the handle 101 clockwise causes the helical coil 130 to screw into the tissue, and rotating the handle 101 counterclockwise causes the helical coil 130 to screw out of the tissue, and vice versa.

[0037] The distal portion 102, shown in detail by circle A in Figure 1A, includes a removable portion 124 and a coupler 126. The removable portion 124 is configured to be coupled to or attached to the distal portion 108D of the control element 108, and / or discoupled from or detached from the distal portion 108D of the control element 108, for example, via the coupler 126. The coupler 126 is configured so that the removable portion 124 can be coupled to and / or discoupled from the control element 108, for example, once or more times throughout the entire procedure. Thus, in some embodiments, the removable portion 124 may be used two or more times throughout the entire procedure.

[0038] In an alternative configuration, the procedure may require two or more removable parts 124. In such a configuration, two or more removable parts 124 may be used with the same coupler 126. For example, a first removable part 124 may be coupled to the coupler 126. Once the first removable part 124 is coupled to the target tissue and discoupled from the coupler 126, a second removable part 124 may then be coupled to the coupler 126. Thus, multiple removable parts 124 may be used with the same coupler 126. In this way, the medical device 100 may be reloadable.

[0039] The removable portion 124 may have a cross-sectional diameter that is larger than, smaller than, or equal to the cross-sectional diameter of the control element 108. For example, the removable portion 124 may have a cross-sectional diameter of 0.05 inches to 0.25 inches (approximately 1.27 mm to approximately 6.35 mm), for example, 0.10 inches to 0.21 inches (approximately 2.54 mm to approximately 5.334 mm). Similarly, the control element 108 may have a cross-sectional diameter of 0.05 inches to 0.25 inches (approximately 1.27 mm to approximately 6.35 mm), for example, 0.10 inches to 0.21 inches (approximately 2.54 mm to approximately 5.334 mm). Thus, in some configurations, the control element 108 has a cross-sectional diameter of approximately 0.10 inches (approximately 2.54 mm) and the removable portion 124 has a cross-sectional diameter of approximately 0.05 inches (approximately 1.27 mm), or vice versa. The control element 108 and the removable portion 124 may, alternatively, have the same cross-sectional diameter.

[0040] The cross-section of the control element 108 may be circular (as shown), oval, elliptical, square, rectangular, hexagonal, or any other shape commonly used in the art. Similarly, the cross-section of the coupler 126 may be circular, semicircular, oval, elliptical, square, rectangular, hexagonal, or any other shape commonly used in the art. The control element 108 and the coupler 126 may have the same cross-sectional shape or different cross-sectional shapes. For example, the control element 108 may have a circular cross-sectional shape, and the coupler 126 may have a rectangular or square cross-sectional shape. Many other combinations are possible.

[0041] Furthermore, the cross-section of the removable portion 124 may be circular (as shown), oval, elliptical, square, rectangular, hexagonal, or any other shape commonly used in the art. The removable portion 124 may have the same or similar cross-sectional shape as the control element 108 and / or the coupler 126. For example, the removable portion 124, the coupler 126, and / or the control element 108 may each have a circular cross-sectional shape. Alternatively, the removable portion 124 may have a hexagonal cross-sectional shape, the coupler 126 may have a rectangular cross-sectional shape, and / or the control element 108 may have a circular cross-sectional shape. Many other combinations are possible. As shown in Figures 1A and 1B, the first portion 126A of the coupler 126 extends distally from the distal portion 108D of the control element 108. The first portion 126A may be coupled (directly or indirectly) to the distal portion 108D of the control element 108. For example, the first portion 126A may be coupled to the distal portion 108D of the control element 108 by, for example, adhesive, welding (e.g., laser welding), swaging, crimping, or any other bonding technique commonly known in the art. In an alternative configuration, the first portion 126A is integrally formed with the distal portion 108D of the control element 108. The first portion 126A and the second portion 126B may be removed or discoupled as described above. Thus, the removable portion 124 may be coupled to and / or discoupled from the control element 108.

[0042] Although not shown, in further alternative configurations, the first portion 126A of the coupler 126 may be coupled to one or more secondary control elements enclosed within the control element 108 or otherwise arranged. In such configurations, each control element 108 may be a sheath having a lumen. Secondary control elements (not shown) may be housed within the lumen of the control element 108 or otherwise arranged. Thus, the secondary control elements may be configured to be movable independently of the control element 108. In such configurations, the first portion 126A and the second portion 126B may be removed or discoupled as described above. In this way, the removable portion 124 may be coupled to and / or discoupled from secondary control elements (not shown).

[0043] As shown in Figure 1B, the cross-sections of the first portion 126A and / or the second portion 126B (for example, perpendicular to the longitudinal axis of the medical device 100 shown in Figure 1A) may be rectangular, triangular, semicircular, semielliptical, circular, oval, or any other shape commonly used in the art. In some configurations, the cross-sections of the first portion 126A and the second portion 126B may be similar or different in shape. For example, the cross-sections of the first portion 126A and the second portion 126B may be semicircular or rectangular. Alternatively, the cross-section of the first portion 126A may be semicircular and the cross-section of the second portion 126B may be rectangular.

[0044] The second portion 126B of the coupler 126 extends proximal to the proximal portion 124A of the removable portion 124. The second portion 126B may be coupled (directly or indirectly) to the proximal portion 124A of the removable portion 124. For example, the second portion 126B may be coupled to the proximal portion 124A of the removable portion 124 by, for example, adhesive, welding (e.g., laser welding), swaging, crimping, or any other bonding technique commonly known in the art. In an alternative configuration, the second portion 126B is formed integrally with the proximal portion 124A of the removable portion 124.

[0045] In these embodiments, the first portion 126A and the second portion 126B can help maintain the connection between the control element 108 and the removable portion 124. The first portion 126A and the second portion 126B also allow the user to separate the first portion 126A and the second portion 126B, and thus separate the control element 108 from the removable portion 124. For example, the first portion 126A and the second portion 126B can be separated by pulling them apart with a force sufficient to overcome the bonding force between them.

[0046] The first portion 126A and the second portion 126B may be detachably coupled. For example, the first portion 126A may comprise a magnet, one or more magnetic materials (e.g., steel, iron, cobalt, nickel, neodymium, etc.) or a magnetic alloy, and the second portion 126B may comprise one or more magnetic materials (e.g., steel, iron, cobalt, nickel, neodymium, etc.) or a magnetic alloy. In these embodiments, the first portion 126A and the second portion 126B have opposite polarities. In further embodiments, the magnet, magnetic material, or magnetic alloy comprising the first portion 126A and / or the magnetic material or magnetic alloy comprising the second portion 126B may be surrounded by an insulating material (e.g., partially or completely sealed). The insulating material can help prevent the magnet or one or more magnetic materials or magnetic alloy from coupling to undesirable components. For example, insulating materials can help prevent magnets or one or more magnetic materials or magnetic alloys from bonding to other medical devices or tools, external magnets, external magnetic materials, etc.

[0047] An insulating material partially or completely surrounding the magnet, magnetic material, or magnetic alloy constituting the first portion 126A and / or the magnetic material or magnetic alloy constituting the second portion 126B can help facilitate local bonding between the first portion 126A and the second portion 126B. For example, partially or completely surrounding the magnet, magnetic material, or magnetic alloy constituting the first portion 126A and / or the magnetic material or magnetic alloy constituting the second portion 126B can help ensure that each time the first portion 126A and the second portion 126B are bonded together, they are bonded in the same orientation.

[0048] The first part 126A and the second part 126B may, additionally or alternatively, be detachably coupled by other mechanisms. For example, the first part 126A and the second part 126B may be detachably coupled via latches, screws, bayonet mounts, snap fits, sliding fits, peelable adhesives, friction fits, or any combination thereof. The first part 126A and the second part 126B may, additionally or alternatively, include one or more keyed features, such as slots, notches, or any combination thereof. Thus, one or more keyed features can enable the first part 126A and the second part 126B to be securely coupled and / or enable the first part 126A and the second part 126B to be repeatedly coupled or uncoupled in the same manner.

[0049] The first portion 126A and the second portion 126B may be disjointed, for example, by breaking, tearing, or otherwise separating the first portion 126A from the second portion 126B. For example, a removable portion 124, not shown, may include one or more tabs and / or one or more perforations between the first portion 126A and the second portion 126B. Thus, the first portion 126A and the second portion 126B may be separated by breaking one or more tabs and / or tearing one or more perforations.

[0050] Additionally or alternatively, the first portion 126A and the second portion 126B may be bonded together by an adhesive or material that degrades when exposed to the patient's gastrointestinal tract. The adhesive material may be located on a portion 127 of the surface 126E of the first portion 126A of the coupler 126, which is in contact with or abuts the surface 126F of the second portion 126B. The portion 127 may comprise part or all of the surface 126E of the first portion 126A. Although not shown, the surface 126F of the second portion 126B of the coupler 126 may additionally or alternatively include a similar portion on the surface 126F of the second portion 126B that is in contact with or abuts the surface 126E of the first portion 126A. For example, the adhesive or material may degrade or decompose due to exposure to the moisture, humidity, temperature, etc., of the body. The adhesive or material may begin to degrade, for example, when portion 127 is not at least partially covered by the outer sheath 110. The adhesive or material may degrade over time, for example, to allow for the placement of the distal portion 102 to or near the treatment site. For example, the distal portion 102, including the first portion 126A and the second portion 126B, may be at least partially covered (for example, by the outer sheath 110) during the delivery of the distal portion 102 to the treatment site. Because the distal portion 102 is at least partially covered by the outer sheath 110, the first portion 126A and the second portion 126B may be shielded from elements of the body so that the degradation of the adhesive or material is prevented or slowed.

[0051] Once the desired position is reached, the distal portion 102 can be extended via the first movable body 106 of the handle 101. The distal portion 102 may be stretched so that the first portion 126A and the second portion 126B are exposed to the moisture, humidity, temperature, etc. of the body, and the adhesive or material begins to decompose or deteriorate. In this way, the first portion 126A and the second portion 126B can be disconnected.

[0052] Additionally or alternatively, the first portion 126A and the second portion 126B may be coupled via an electromagnetic principle. For example, the first portion 126A may include an electromagnet, and the second portion 126B may be composed of a magnetic material. Thus, the first portion 126A can be magnetized and demagnetized to be selectively coupled to and / or uncoupled from the second portion 126B. In this configuration, the control element 108 may include one or more lumens (not shown) for housing the wires or cables necessary to power the electromagnet of the first portion 126A. Additionally, the handle 101 may include one or more ports or plugs (not shown) so that the medical device 100 can be coupled to a power source, for example, to provide energy to the electromagnet of the first portion 126A. In an alternative embodiment, the handle 101 includes an internal power source configured to magnetize and / or demagnetize the electromagnet of the first portion 126A.

[0053] In some configurations, the first portion 126A and the second portion 126B may overlap at least partially when joined, as shown in Figure 1A. For example, the distal surface 126C of the first portion 126A may be distal to the proximal surface 126D of the second portion 126B, and the proximal surface 126D of the second portion 126B may be proximal to the distal surface 126C of the first portion 126A. In an alternative configuration, the distal surface of the first portion 126A and the proximal surface of the second portion 126B are detachably joined so that neither portion of the first portion 126A nor the second portion 126B overlaps.

[0054] The first portion 126A may have a shape that is at least partially complementary to the second portion 126B, or vice versa. For example, the surface 126F of the second portion 126B may be concave. Thus, the surface 126E of the first portion 126A that contacts or abuts the surface 126F of the second portion 126B may be convex, for example, so that the surface 126E of the first portion 126A is in partial or complete contact with the surface 126F of the second portion 126B. Similarly, the surface 126F of the second portion 126B may include one or more protrusions, projections, ridges, depressions, cavities, etc. Thus, the surface 126E of the first portion 126A may have a complementary shape, for example, so that the surface 126E of the first portion 126A is in partial or complete contact with the surface 126F of the second portion 126B.

[0055] The loop 128 is connected to the removable portion 124. For example, at least a portion of the loop 128 may be located proximal to the most distal portion 124C of the removable portion 124 and distal to the proximal portion 124A of the removable portion 124. The first portion 128A of the loop 128 may extend at least partially around the outer surface of the removable portion 124.

[0056] The first portion 128A of the loop 128 may be bonded to the outer surface of the removable portion 124 by means of, for example, adhesive, welding (e.g., laser welding), swaging, crimping, or any other bonding technique commonly known in the art. Additionally or alternatively, the outer surface of the removable portion 124 may include grooves (not shown) so that the first portion 128A of the loop 128 may be bonded to the outer surface of the removable portion 124 by, for example, mechanical fitting, snap fitting, press-fitting, or any other bonding technique commonly known in the art. In some embodiments, the first portion 128A of the loop 128 may be made of one or more resilient materials, such as, for example, an elastic polymer or rubber material, or any other material commonly used in the art. The first portion 128A of the loop 128 may additionally or alternatively be made of Teflon® or nylon filament (e.g., similar to dental floss), or one or more suture materials (e.g., surgical steel, silk, cotton, and / or linen).

[0057] In alternative embodiments, the first portion 128A of the loop 128 is made of one or more rigid or semi-rigid materials, such as metal, polymer, or metal-polymer composite material. In some embodiments, the first portion 128A of the loop 128 forms a continuous loop. In alternative embodiments (not shown), the first portion 128A is C-shaped or forms a discontinuous loop. The cross-section of the first portion 128A of the loop 128 may be circular, oval, elliptical, square, rectangular, hexagonal, or any other shape commonly used in the art.

[0058] The second portion 128B of the loop 128 may extend radially outward from the removable portion 124. In some embodiments, the second portion 128B forms a continuous loop. The second portion 128B of the loop 128 may be composed of one or more resilient materials, such as an elastic polymer or rubber material, or any other material commonly used in the art. The second portion 128B of the loop 128 may additionally or alternatively be composed of Teflon® or nylon filament (e.g., similar to dental floss), or one or more suture materials (e.g., surgical steel, silk, cotton, and / or linen). The second portion 128B may be composed of the same material as the first portion 128A or a different material. For example, the second portion 128B may be composed of the first rubber material, and the first portion 128A may be composed of a second rubber material different from the first rubber material. Various other combinations of materials are also possible. The cross-section of the second portion 128B may be circular, oval, elliptical, square, rectangular, hexagonal, or any other shape commonly used in the art. In some configurations, the second portion 128B is larger than the first portion 128A. For example, the second portion 128B may have a larger circumference and / or diameter than the first portion 128A.

[0059] The distal portion 102 further includes a helical coil 130. The helical coil 130 is configured to be bonded to and detached from tissue. The helical coil 130 may be located at least partially within a cavity or lumen 132 of the removable portion 124. At least a portion of the helical coil 130 may be distal to the most distal end 124D of the removable portion 124. The helical coil 130 may consist of a plurality of windings bonded (directly or indirectly) to the removable portion 124. The helical coil 130 may be bonded (directly or indirectly) to the removable portion 124 by, for example, welding (e.g., laser welding), adhesive, mechanical fitting, snap fitting, crimping, swaging, or other mechanisms commonly known in the art. In an alternative configuration, the helical coil 130 is formed integrally with the removable portion 124. For example, the wire or coil forming the helical coil 130 may have or be formed a removable portion 124. In such a configuration, the helical coil 130 forms at least the most distal portion 124C of the removable portion 124.

[0060] The helical coil 130 may include, for example, 1 to 10 complete helical windings or windings, or 3 to 5 complete helical windings. In some configurations, the windings forming the helical coil 130 may be evenly spaced apart. In alternative configurations, the spacing between each of the windings forming the helical coil 130 may vary. For example, in the proximal region 130A of the helical coil 130, one or more adjacent windings may be spaced a first distance apart. For example, the windings forming the helical coil 130 within the proximal region 130A may be in contact with each other. In the distal region 130C of the helical coil 130, adjacent windings may be spaced a second distance apart. For example, in the intermediate region 130B between the proximal region 130A and the distal region 130C, adjacent windings may be spaced a third distance apart. In some configurations, the second distance may be greater than the third distance, and the third distance may be greater than the first distance. Many other configurations are possible. In a further configuration, the second distance is equal to the third distance such that the intermediate region 130B and the distal region 130C are similarly separated.

[0061] In a further configuration, the windings forming the intermediate region 130B may have a non-constant pitch, resulting in a gradual increase in spacing. For example, the windings within the intermediate region 130B may transition from adjacent windings in contact with each other in the proximal region 130A to windings separated in the distal region 130C.

[0062] The distal tip 130D of the helical coil 130 may be narrowed or sharpened, for example, to more easily puncture or penetrate the target tissue. In some embodiments, the distal tip 130D of the helical coil 130 is oriented in a bent or curved configuration, for example, so that the distal tip 130D of the helical coil 130 is parallel or substantially parallel to the windings forming the helical coil 130. In such configurations, the distal tip 130D may be less likely to puncture or penetrate the surrounding tissue of the target area. The helical coil 130 may be formed from a solid circular wire or multiple wires. In some configurations, the helical coil 130 may be configured to have a diameter less than the inner diameter of the removable portion 124. For example, the helical coil 130 may have an outer cross-sectional diameter of 0.002 inches to 0.200 inches (approximately 0.0508 mm to approximately 5.08 mm), for example, 0.005 inches to 0.020 inches (approximately 0.127 mm to approximately 0.508 mm). The helical coil 130 may have an inner cross-sectional diameter of 0.001 inches to 0.190 inches (approximately 0.0254 mm to approximately 4.826 mm), for example, 0.002 inches to 0.015 inches (approximately 0.0508 mm to approximately 0.381 mm). In some configurations, the wires forming the helical coil 130 may have a cross-sectional diameter greater than or equal to the wires forming the removable portion 124. In alternative configurations, the wires forming the helical coil 130 may have a cross-sectional diameter smaller than the wires forming the removable portion 124. For example, the wire forming the helical coil 130 may have a cross-sectional diameter of 0.0005 inches to 0.100 inches (approximately 0.0127 mm to approximately 2.54 mm), for example, 0.005 inches to 0.015 inches (approximately 0.127 mm to approximately 0.381 mm).

[0063] Although not shown in the figures, the helical coil 130 may include one or more markers, such as radiopaque markers and ultrasonic markers, to help the user determine the state, position, and operating state of the helical coil 130. For example, the windings or parts of the windings in the proximal region 130A and / or intermediate region 130B may include markers to inform the user how deep the helical coil 130 is in the tissue, how many windings of the helical coil 130 have been inserted into the tissue, etc.

[0064] Still referring to Figure 1A, the control element 108 may extend from one or more portions of the handle 101 of the medical device 100 (e.g., from the distal portion of the first movable body 106) to one or more portions of the distal portion 102. Each control element 108 may be formed from a wire, coil, tube, etc. Additionally, the outer sheath 110 may extend from one or more portions of the handle 101 (e.g., from the distal portion of the distal handle portion 111) to one or more portions of the distal portion 102. The outer sheath 110 may be formed from a coil, braid, tube, sheath, etc., and the lumen 113 may extend longitudinally within the outer sheath 110 to receive, for example, a portion of the control element 108. In these embodiments, the control element 108 may be located radially inward of the outer sheath 110. For example, the control element 108 is movable longitudinally and / or rotatably relative to the outer sheath 110 and may be at least partially positioned within the lumen 113 of the outer sheath 110.

[0065] For example, in some configurations, such as when the medical device 100 is in a retracted or closed configuration, at least a portion of the distal portion 102 is also located within the lumen 113 of the outer sheath 110. For example, the helical coil 130 may be located within the most distal end 110A of the outer sheath 110, or it may be located proximal to the most distal end 110A. In such configurations, the first movable body 106 may be located proximal, for example, within the handle slot 114.

[0066] In an alternative configuration, the medical device 100 may not include the external sheath 110, the first movable body 106, and / or the second movable body 118. In such a configuration, the medical device 100 may simply include a gripping portion for the user to grasp the medical device 100, for example, a proximal portion of the medical device 100, and a distal portion 102 with a removable portion 124. The distal portion 102 may be directly or indirectly coupled to the gripping portion, for example, by a control element 108. In such an embodiment, the helical coil 130 of the removable portion 124 can be advanced into the tissue by rotating the gripping portion, and thus rotating the control element 108 and the helical coil 130. The removable portion 124 can be disengaged, for example, by pulling or biasing the gripping portion proximal to overcome any connecting force between the removable portion 124 and the rest of the medical device 100. In this configuration, the medical device 100 may contain fewer components and therefore be easier to manufacture or produce and / or less expensive.

[0067] Figure 1B shows the distal portion 102 in a second configuration or a detached configuration. For example, in the detached configuration, the first portion 126A of the coupler 126 is detached or discoupled from the second portion 126B of the coupler 126. The first portion 126A and the second portion 126B can be detached or discoupled as described above. Thus, the detachable portion 124 is discoupled or detached from the control element 108.

[0068] The cross-sections of the first portion 126A and / or the second portion 126B (for example, perpendicular to the longitudinal axis of the medical device 100 shown in Figure 1A) may be rectangular, triangular, semicircular, semielliptical, circular, oval, or any other shape commonly used in the art. In some configurations, the cross-sections of the first portion 126A and the second portion 126B may be similar or different. For example, the cross-sections of the first portion 126A and the second portion 126B may be semicircular or rectangular. Alternatively, the cross-section of the first portion 126A may be semicircular and the cross-section of the second portion 126B may be rectangular.

[0069] Referring here to Figure 2A, a medical system 200 is shown. The medical system 200 includes a medical device 100 (described above and shown in Figures 1A and 1B) and an endoscope 252. The medical device 100 may be located within the working channel or lumen 254 of the endoscope 252. In an alternative configuration (not shown), the medical device 100 may extend outside the endoscope 252 (e.g., along the outer surface of the endoscope 252) without extending, for example, through the working channel 254. Alternatively, one or more parts of the medical system 200 may be inserted, and / or surrounded by, for example, an insertion sheath (not shown) surrounding the endoscope 252. Additionally, Figure 3 shows an exemplary method or process 300 that one or more users may perform using any of the medical systems, devices, or parts of the system described herein, e.g., medical system 200.

[0070] Although not shown, one or more portions of the endoscope 252 (e.g., the distal portion 252A) may be flexible, for example, via one or more knobs, levers, buttons, or other control units on the proximal handle (not shown) of the endoscope 252. In these embodiments, the distal portion 252A of the endoscope 252 may be operated while being delivered to the treatment site through the body lumen and / or positioned in a retroflex position relative to the treatment site, for example, when the treatment site is in the esophagus, stomach, duodenum, colon, or other part of the gastrointestinal tract. Thus, at least a portion of the medical device 100 may be flexible or semi-flexible, for example, to be operated together with the endoscope 252.

[0071] Additionally, the distal surface 252D of the endoscope 252 may include one or more visualization devices 256 (e.g., one or more cameras, light-emitting diodes (LEDs), one or more image sensors, an endoscope viewing element, an optical assembly including one or more image sensors and one or more lenses). The distal surface 252D of the endoscope 252 may additionally or alternatively include one or more openings 258 configured to supply liquid, gas, and / or suction to a body lumen or treatment site.

[0072] Referring to Figures 2A and 3, in step 302, the medical system 200 (e.g., the distal portion of the medical system 200) may be inserted into the body lumen 260 of the subject, for example, through a natural opening or incision, up to the treatment site 262. Before or after the medical system 200 reaches the treatment site 262, the first movable body 106 (shown in Figure 1A) may be actuated distally within the handle slot 114 of the handle 101 so that the control element 108 is actuated distally, extended, pushed, or biased, and so that at least a portion of the distal portion 102 is distal to the most distal end 110A of the outer sheath 110.

[0073] The endoscope 252 and / or medical device 100 may then be operated to position the helical coil 130 of the medical device 100 in contact with the wall 261 of the lumen 260, for example, from the treatment site 262 to the opposite side of the lumen 260, or across the lumen 260. The endoscope 252 may be operated, for example, by bending the distal portion 252A, advancing the endoscope 252 distally, and / or retracting the endoscope 252 proximally. Additionally or alternatively, a visualization device 256 may be used to operate and / or reposition the endoscope 252. Similarly, the medical device 100 may be operated, for example, by advancing the medical device 100 distally, and / or retracting the medical device 100 proximally.

[0074] When the helical coil 130 comes into contact with the wall 261 of the lumen 260, the control element 108, and therefore the distal portion 102 and the helical coil 130, can be rotated in a first direction (e.g., clockwise or counterclockwise). The control element 108 can be rotated, for example, by rotating the second movable body 118 (shown in Figure 1A) in the first direction. Thus, when the helical coil 130 is rotated in the first direction, the distal tip 130D of the helical coil 130 can puncture the wall 261 of the lumen 260. Continued rotation of the helical coil 130 in the first direction allows the distal tip 130D to advance deeper into the tissue of the wall 261, for example, in a corkscrew manner.

[0075] Therefore, as shown in Figure 2A and described in step 304, the helical coil 130 may be fixed or coupled to the wall 261 of the lumen 260, for example, from the treatment site 262 to the opposite side of the lumen 260, or across the lumen 260. One or more windings of the helical coil 130 may be embedded in the wall 261 of the lumen 260, for example, so that the helical coil 130 is securely fixed, coupled, or attached to the wall 261 of the lumen 260. The markers mentioned above in Figure 1A may be used, for example, to determine how many windings are inside the wall 261 of the lumen 260, or which part of the helical coil 130 is inside.

[0076] As shown in Figure 2B, in step 306, the removable part 124 is then discoupled or removed from the control element 108 (Figure 1B). The removable part 124 can be discoupled from the control element 108, for example, by pulling or retracting the control element 108 so that a pulling or retracting force overcomes the connecting force between the first part 126A (shown in Figures 1A, 1B, and 2A) and the second part 126B of the coupler 126. In this way, the removable part 124 remains attached to or coupled to the wall 261, while the rest of the medical device 100 is pulled and / or retracted in the proximal direction.

[0077] Referring further to Figure 2B, the medical system 200 may further include a device 264 having a clip 266. Additionally, the medical system 200 may include a cutting tool 268 (shown in Figures 2C and 2E). The device 264 and the cutting tool 268 will be described in more detail below. Each of the device 264 and the cutting tool 268 may be configured to be positioned within the working channel 254 of the endoscope 252. For example, the device 264 may be inserted into the working channel 254 of the endoscope 252. The cutting tool 268 may be inserted into the working channel 254 before the device 264 is removed from the working channel 254, while the device 264 is being removed from the working channel 254, or after the device 264 has been removed from the working channel 254. As shown in Figures 2B to 2E, the clip 266 may be any clip commonly used in the art, for example, the clip 266 may be a hemoclip or an endoclip. The clip 266 may include a first leg portion 266A and a second leg portion 266B.

[0078] Still referring to Figure 2B, after the removable portion 124 of the medical device 100 is fixed to the wall 261 of the lumen 260, the device 264 may be inserted through the working channel 254 of the endoscope 252 such that the distal portion of the device 264 is distal to the distal surface 252D of the endoscope 252. A portion of the second portion 128B of the loop 128 may be positioned within the clip 266, for example, between the first leg 266A and the second leg 266B. To position the second portion 128B of the loop 128 between the first leg 266A and the second leg 266B, the endoscope 252 may be pushed distally, pulled proximal, rotated or bent within the lumen 260, and / or the device 264 may be pushed distally, pulled proximal or rotated within the working channel 254 of the endoscope 252.

[0079] In some configurations, the endoscope 252 may be oriented so that the working channel 254 is positioned closer to the second portion 128B in order to assist in positioning the second portion 128B between, for example, the first leg 266A and the second leg 266B. For example, the endoscope 252 may be oriented so that the working channel 254 is at the 6 o'clock position relative to the visualization device 256 and / or the opening 258, as shown. In alternative configurations, the endoscope 252 may be oriented so that the working channel 254 is at the 3 o'clock, 9 o'clock, or 12 o'clock position relative to the visualization device 256 and / or the opening 258. In this way, the endoscope 252 may be rotated so that the working channel 254 is properly positioned and / or oriented in order to connect the device 264 to the second portion 128B of the loop 128. Many other configurations are possible, for example, to assist in positioning the second portion 128B between the first leg 266A and the second leg 266B of the clip 266.

[0080] Referring to Figures 2B and 3, in step 308, the clip 266 may be joined to or secured to the treatment site 262. The clip 266 is then released from the rest of the device 264. Thus, the second portion 128B of the loop 128 may be secured to the treatment site 262, for example, between the clip 266 and the treatment site 262. In this way, the second portion 128B may be secured to the treatment site 262 between the first leg 266A and the second leg 266B of the clip 266. With the removable portion 124 secured to the wall 261 of the lumen 260 and the second portion 128B of the loop 128 secured to the treatment site 262, the second portion 128B of the loop 128 is subjected to tension, and the tissue of the treatment site 262 may be lifted at least partially or similarly subjected to tension.

[0081] As shown in Figure 2C, once the device 264 is removed from the working channel 254, a cutting tool 268, such as a knife, scissors, blade, electrocautery knife, or any other excision or cutting device, can be introduced through the working channel 254 of the endoscope 252. In step 309, the cutting tool 268 can be used to cut or excise tissue at least partially from the treatment site 262. The tension of the second portion 128B can help lift the excised tissue of the treatment site 262, for example, when the treatment site 262 is cut or excised. Thus, once the excised tissue of the treatment site 262 is lifted, the tension of the second portion 128B decreases, and the second portion 128B can return to its original position.

[0082] As shown in Figure 2D and described in the optional step 310, the removable portion 124 may be reattached to or mounted to the medical device 100 as described below. Then, in the optional step 312, the helical coil 130 may be repositioned within the lumen 260. Thus, the second portion 128B of the loop 128 may be tensioned again, for example, with respect to the treatment site 262, for example, by repositioning the helical coil 130.

[0083] To reposition the helical coil 130 and then re-tension the second portion 128B, the medical device 100 (without the removable portion 124) can be reinserted through the working channel 254 of the endoscope 252. The medical device 100 can be reinserted through the working channel 254 of the endoscope 252, for example, when the cutting tool 268 is removed from the working channel 254 of the endoscope 252. Using the endoscope 252, the medical device 100 can be manipulated so that the first portion 126A of the coupler 126 contacts the second portion 126B of the coupler 126. The first portion 126A and the second portion 126B can then be rejoined or reattached according to the mounting mechanism described above. In this way, the removable portion 124 can be attached to or coupled to the control element 108.

[0084] When the removable part 124 is coupled to the control element 108, the control element 108 can then be rotated in a second direction opposite to the first direction (for example, counterclockwise or clockwise). Thus, when the control element 108 is rotated in the second direction, the helical coil 130 is also rotated in the second direction, and as a result, for example, the helical coil 130 can be disengaged from or withdrawn from the wall 261 of the lumen 260.

[0085] When released from or withdrawn from the wall 261 of the lumen 260, the removable portion 124 and the helical coil 130 may be repositioned, for example, distal to the treatment site 262, so that the second portion 128B of the loop 128 is again subjected to tension. For example, the endoscope 252 and / or medical device 100 may then be operated to reposition the helical coil 130 of the medical device 100, for example, to the opposite side of the lumen 260 from the treatment site 262, or across the lumen 260, so that it is in contact with the wall 261 of the lumen 260. The endoscope 252 may be operated, for example, by bending the distal portion 252A, advancing the endoscope 252 distally, and / or retracting the endoscope 252 proximally. The medical device 100, including the removable portion 124 and the helical coil 130, may be operated, for example, by advancing the medical device 100 distally and / or retracting the medical device 100 proximal to the other.

[0086] Through the optional steps 310 and 312, the second portion 128B of the loop 128 may remain fixed to the treatment site 262, for example, between the first leg 266A and the second leg 266B of the clip 266.

[0087] As shown in Figure 2E, the removable portion 124 can again be removed from or disconnected from the control element 108, as previously described. For example, once the medical device 100 is removed from the working channel 254 of the endoscope 252, the cutting tool 268 can be reintroduced, for example, through the working channel 254 of the endoscope 252. The cutting tool 268 can then be used in an optional step 314 to continue cutting or excising tissue from the treatment site 262. Optional steps 310, 312, and / or 314 may be repeated, for example, until the treatment site 262 is excised to the desired amount, so that the helical coil 130 is repositioned and / or the second portion 128B of the loop 128 can be tensioned again and again. Additionally or alternatively, optional steps 310 and 312 may be performed, for example, after the helical coil 130 has been joined to the wall 261 of the lumen 260, if the second portion 128B does not have the desired tension, or if the placement of the removable portion 124 is inappropriate, before tissue is excised from the treatment site 262 in step 309.

[0088] If the tissue is properly excised from the treatment site 262 in step 309 or the optional step 314, in step 316, the removable portion 124, and therefore the helical coil 130, may be removed from the wall 261, as described above. For example, if the cutting tool 268 is removed from the working channel 254 of the endoscope 252, the medical device 100 may be reintroduced through the working channel 254 of the endoscope 252. The medical device 100 may be manipulated (for example, by manipulating the medical device 100 and / or the endoscope 252) such that the first portion 126A of the coupler 126 is again in contact with the second portion 126B of the coupler 126. The first portion 126A and the second portion 126B may then be rejoined or reattached according to the attachment mechanism described above. In this way, the removable portion 124 may be reattached or rejoined to the control element 108, retracted proximal, or removed. One or more parts of the medical system 200 may then be retracted proximally or removed. For example, the medical device 100, the cutting tool 268, and / or the endoscope 252 may be retracted proximally or removed. Thus, tissue excised from the treatment site 262 attached to the medical device 100 and / or clip 266 may then be removed from the lumen 260.

[0089] In an alternative embodiment, the helical coil 130 may be biodegradable. For example, the wires forming the helical coil 130 may disintegrate or break down so that the removable portion 124 can be removed from the wall 261. The removable portion 124 can then be removed using a basket, gripper, net, cage, suction, or other gripping tool or method. Alternatively, the removable portion 124 may be allowed to pass through naturally by the object. In this way, the removable portion 124 can be removed from the wall 261 without the need to reattach or reassemble the removable portion 124 to the medical device 100.

[0090] In some embodiments, the cutting tool 268 is used to remove the second portion 128B of the loop 128 from the medical device 100, and as a result, for example, the tissue excised from the treatment site 262 can be removed through the working channel 254 of the endoscope 252, either by being allowed to pass naturally by the subject or by applying, for example, suction. Not shown, in some embodiments, the tissue excised from the treatment site 262 can be removed through the working channel 254 of the endoscope 252, for example, by using one or more grippers, nets, cages, suction, or any other device or method commonly used in the art to remove objects or substances from a subject.

[0091] Each embodiment described herein may allow a user to apply tension to tissue in order to lift the tissue so that it can be more easily cut, excised, removed, or otherwise treated. Each embodiment may help reduce treatment time, the possibility of patient injury, and / or other treatment complications.

[0092] It will be apparent to those skilled in the art that various modifications and variations can be made to the disclosed devices without departing from the scope of this disclosure. Other embodiments of this disclosure will be apparent to those skilled in the art from the examination of this specification and the practice of the invention disclosed herein. This specification and the examples are for illustrative purposes only, and the true scope and technical idea of ​​the invention are intended to be shown by the following claims.

Claims

1. It is a medical system, An insertion device having a work channel, A first medical device configured to be positioned within the working channel of the insertion device, The handlebars and A control element extending from the handle, A removable portion is detachably coupled to the distal portion of the control element, A spiral coil connected to the aforementioned removable part, A loop, wherein a first portion of the loop is connected to the removable portion, and a second portion of the loop extends radially away from the removable portion, and A first medical device including, A second medical device configured to be positioned within the working channel of the insertion device, A medical system comprising, wherein the second medical device is configured to receive the second portion of the loop, and the second medical device is configured to connect the second portion of the loop to a part of the treatment site.

2. The medical system according to claim 1, wherein the first medical device further includes a coupler, the coupler including a first portion which is coupled to the distal portion of the control element or is a part of the distal portion of the control element, the coupler including a second portion which is coupled to the proximal portion of the removable portion or is a part of the proximal portion of the removable portion, and the first portion and the second portion are configured to releasably couple the removable portion to the control element.

3. The medical system according to claim 2, wherein the first portion of the coupler is configured to overlap with at least a portion of the second portion of the coupler.

4. The medical system according to claim 2 or 3, wherein the first contact surface of the first portion abuts against the second contact surface of the second portion, and the first contact surface of the first portion has a shape complementary to the second contact surface of the second portion.

5. A medical system according to any one of claims 2 to 4, wherein a portion of the first part of the coupler is magnetic, and a portion of the second part of the coupler is magnetic with the opposite polarity to that of the portion of the first part.

6. A medical system according to any one of claims 2 to 5, wherein a portion of the first part of the coupler is equipped with an electromagnet, and a portion of the second part of the coupler is made of a magnetic material.

7. The medical system according to any one of claims 1 to 6, wherein rotation of the helical coil in a first direction is configured to connect the distal portion to the tissue wall, and rotation of the helical coil in a second direction is configured to disconnect the helical coil from the tissue wall.

8. The medical system according to any one of claims 1 to 7, wherein the helical coil includes a plurality of windings, adjacent windings of a first portion of the plurality of windings are separated by a first distance, adjacent windings of a second portion of the plurality of windings are separated by a second distance, and adjacent windings of a third portion of the plurality of windings are separated by a third distance.

9. The medical system according to claim 8, wherein the third distance is greater than the second distance, and the second distance is greater than the first distance.

10. The medical system according to any one of claims 1 to 9, wherein the handle includes a stationary body, a first movable body, and a second movable body, the first movable body controls the axial movement of the distal portion of the control element, and the second movable body controls the rotational movement of the distal portion of the control element.

11. The medical system according to claim 10, wherein the stationary body includes a first indicator for identifying the axial movement of the helical coil, and the second movable body includes a second indicator for identifying the rotational movement of the helical coil.

12. The medical system according to any one of claims 1 to 11, wherein the second medical device includes a clip.

13. The medical system according to any one of claims 1 to 12, wherein the second portion of the loop is made of an elastic material.

14. The medical system according to any one of claims 1 to 13, comprising a third medical device configured to be positioned within the working channel of the insertion device, wherein the third medical device is configured to cut tissue.

15. The first part of the coupler and the second part of the coupler are joined together by an adhesive material. In the first configuration, the adhesive material is placed within a sheath extending from the handle. In the second configuration, the adhesive material is not covered by the sheath. The medical system according to any one of claims 2 to 6, wherein the adhesive material deteriorates, and the connection between the first part of the coupler and the second part of the coupler is released.

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