Intrauterine tissue sampling

Abstract

To provide an intrauterine tissue sampling implement capable of sampling target tissues more reliably.SOLUTION: An intrauterine tissue sampling implement 1 includes: a tissue sampling end 10; a shaft part 30 extending backward from a rear end of the tissue sampling end 10; and a grip part 50 provided at a rear end of the shaft part 30. The tissue sampling end 10 is provided with an oval annular frame 11 having a major diameter in a back and forth direction. The oval annular frame 11 is provided with an oval through hole 12 having a major diameter in the back and forth direction. An inner surface of a front end side part of at least the oval through hole 12 is a recessed surface 13 extending into the oval annular frame 11, and an inner edge of a front surface and a back surface of the oval annular frame 11 at a part having the recessed surface 13 are edge parts 14, 15 scraped inward. The intrauterine tissue sampling implement 1 is integrally formed of synthetic resin. The shaft part 30 can be bent by hand to form a curved part 31 in plastic deformation.SELECTED DRAWING: Figure 1

Description

[Technical field]

[0001] The present invention relates to an intrauterine tissue sampling device for insertion into a uterus to sample tissue (cells, etc.). [Background technology]

[0002] When collecting tissue (cells, etc.) from inside the body (inside a body cavity, organ, etc.) for diagnostic or therapeutic purposes (including collection for removal), a long, thin, spoon-shaped tissue collection tool (curette) with a sharp front end (tip) is used. For example, when sampling intrauterine tissue, a long, thin metal instrument (intrauterine tissue sampling tool) is conventionally inserted through the cervix, and the procedure is performed while taking care not to damage the normal endometrium. Patent Document 1 (JP Patent Publication No. 2001-522683) discloses a resin medical spatula that can be used as a spatula for exfoliated cytology for examining the cervix or uterine vagina (PAP test). Patent Document 2 (JP Patent Publication 52-044099A) discloses an intrauterine tissue sampling tool (intrauterine tissue sampling device) with a tissue sample sampling part including a spiral end, which is capable of sampling tissue from the endometrium. It also discloses that the tissue sample sampling part (spiral blade) is curved with a predetermined radius of curvature (e.g., so as to approximately coincide with the axis of the uterus relative to the vaginal canal). [Prior art documents] [Patent documents]

[0003] [Patent Document 1] Special Publication No. 2001-522683 [Patent Document 2] Japanese Patent Application Publication No. 52-044099 Summary of the Invention [Problem to be solved by the invention]

[0004] In a conventional intrauterine tissue collecting tool for collecting intrauterine tissue, the collected tissue may fall off from the intrauterine tissue collecting tool. In addition, in the case of the intrauterine tissue collecting tool disclosed in Patent Document 2, when bending the part (spiral blade) to be inserted into the body into a desired shape, the load required to bend the part varies depending on the part and direction to be bent, so that it is difficult to obtain the desired shape. Therefore, the present invention provides an intrauterine tissue sampling tool that can more reliably sample a target tissue. [Means for solving the problem]

[0005] The above objectives are achieved by the following: (1) An intrauterine tissue sampling device having a tissue sampling tip that can be inserted into a uterus, the intrauterine tissue sampling tool comprises the tissue sampling tip portion, a shaft portion extending rearward from a rear end of the tissue sampling tip portion, and a grip portion provided at a rear end of the shaft portion; The tissue sampling tip portion has an elliptical annular frame having a major axis in the front-rear direction of the intrauterine tissue sampling tool, and the elliptical annular frame has an elliptical through hole having a major axis in the front-rear direction of the intrauterine tissue sampling tool, and further At least an inner surface of a front end portion of the elliptical through hole is a concave surface extending into the elliptical annular frame, and inner edges of the front and back surfaces of the elliptical annular frame in the portion having the concave surface are edge portions cut inward, The outer peripheral surface of the elliptical annular frame is rounded without edges, The intrauterine tissue sampling tool is integrally formed from a synthetic resin, and the shaft portion can be manually bent to form a plastically deformed curved portion.

[0006] (2) An intrauterine tissue sampling device as described in (1) above, wherein the inner surfaces of the front end portion and both sides in the minor axis direction of the elliptical through-hole are concave surfaces extending into the elliptical annular frame, and the inner edges of the front and back surfaces of the elliptical annular frame in the portions having the concave surfaces are edged inwardly. (3) An intrauterine tissue sampling device as described in (1) above, wherein the entire inner surface of the elliptical through-hole is a concave surface extending into the elliptical annular frame, and the entire inner edges of the front and back of the elliptical annular frame are formed into inwardly scraped edges. (4) The gripping portion has a cross-sectional outer shape of a substantially elongated rectangle, The shaft portion includes a front end side connecting portion whose cross section changes from a substantially circular shape to a substantially rectangular shape toward the front end, a central portion connected to the front end side connecting portion, and a grip portion connecting portion connected to the central portion, and the central portion includes a tapered portion whose cross section is substantially circular and whose diameter becomes smaller toward the front end. (5) An intrauterine tissue sampling tool as described in any of (1) to (4) above, wherein the gripping portion is formed in an elongated plate shape and has wide front and rear surfaces facing each other, the front surface of the gripping portion faces the same direction as the front surface of the elliptical annular frame of the tissue sampling tip portion, and the rear surface of the gripping portion faces the same direction as the rear surface of the elliptical annular frame of the tissue sampling tip portion. (6) The intrauterine tissue sampling tool according to the above (5), wherein the gripping portion has recesses formed in the front and rear portions. (7) The intrauterine tissue sampling tool according to any one of (1) to (6) above, wherein the gripping portion is provided with a plurality of annular anti-slip ribs provided perpendicular to the longitudinal direction. Effect of the Invention

[0007] The intrauterine tissue sampling tool of the present invention has a tissue sampling tip portion equipped with an elliptical annular frame having a major axis in the front-rear direction of the intrauterine tissue sampling tool, the elliptical annular frame having an elliptical through-hole having a major axis in the front-rear direction of the intrauterine tissue sampling tool, and further, at least the inner surface of the front end side portion of the elliptical through-hole is a concave surface extending into the elliptical annular frame, and the inner edges of the front and back surfaces of the elliptical annular frame in the portion having the concave surface are edge portions scraped inwardly. Therefore, the edge portions allow the target intrauterine tissue to be sampled more reliably, and the concave surface of the through-hole allows the intrauterine tissue once sampled to be held so as not to fall out.

[0008] In addition, the intrauterine tissue sampling tool of the present invention is integrally formed from synthetic resin, and the shaft portion can be bent by hand to form a curved portion through plastic deformation. Therefore, the shape of the intrauterine tissue sampling tool can be adjusted according to the shape of the uterus and the position of the intrauterine tissue to be sampled within the uterus, and the target intrauterine tissue can be sampled more reliably. [Brief description of the drawings]

[0009] [Figure 1] FIG. 1 is a perspective view showing an embodiment of an intrauterine tissue sampling device of the present invention. [Diagram 2] FIG. 2 is a front view of the intrauterine tissue sampling tool shown in FIG. 1 rotated 90 degrees to the left. [Diagram 3] FIG. 3 is a left side view of the intrauterine tissue sampling tool shown in FIG. 1 rotated 90 degrees to the left. [Figure 4] FIG. 4 is an enlarged explanatory view of a portion A in FIG. [Diagram 5] FIG. 5 is a cross-sectional view taken along line CC of FIG. [Figure 6] FIG. 6 is a cross-sectional view taken along line DD of FIG. [Figure 7] FIG. 7 is a cross-sectional view taken along line BB of FIG. [Figure 8] FIG. 8 is an explanatory diagram for explaining a state in which the intrauterine tissue collecting tool shown in FIG. 1 is used. [Figure 9]FIG. 9 is an explanatory diagram for explaining a state in which the intrauterine tissue collecting tool shown in FIG. 1 is used. [Figure 10] FIG. 10 is an explanatory cross-sectional view corresponding to FIG. 6, for explaining another embodiment of the intrauterine tissue sampling device of the present invention. [Figure 11] FIG. 11 is an explanatory cross-sectional view corresponding to FIG. 5, for explaining another embodiment of the intrauterine tissue sampling device of the present invention. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0010] The intrauterine tissue sampling device of the present invention will be described with reference to the embodiment shown in the drawings. In this embodiment, the left-right direction in Fig. 2 is taken as the front-rear direction.

[0011] The intrauterine tissue collection tool 1 of the present invention is an intrauterine tissue collection tool 1 having a tissue collection tip portion 10 that can be inserted into a uterus, and the intrauterine tissue collection tool 1 comprises the tissue collection tip portion 10, a shaft portion 30 that extends rearward from the rear end of the tissue collection tip portion 10, and a grip portion 50 provided at the rear end of the shaft portion 30. The tissue collection tip portion 10 comprises an elliptical annular frame 11 having a major axis in the front-rear direction of the intrauterine tissue collection tool 1, and the elliptical annular frame 11 has an elliptical through hole 1 having a major axis in the front-rear direction of the intrauterine tissue collection tool 1. 2, further comprising at least an inner surface of a front end portion of the elliptical through-hole 12 which forms a concave surface 13 extending into the elliptical annular frame 11, and the inner edges of the front and back surfaces of the elliptical annular frame 11 in the portion having the concave surface 13 form inwardly scraped edge portions 14, 15, and the outer circumferential surface of the elliptical annular frame 11 is rounded and has no edges, the intrauterine tissue sampling tool 1 is integrally formed from a synthetic resin, and the shaft portion 30 can be manually bent to form a plastically deformed curved portion 31.

[0012] Specifically, as shown in Figures 1 to 3, the intrauterine tissue collecting tool 1 has a tissue collecting tip 10 at its front end. As shown in Figure 2, the tissue collecting tip 10 has an elliptical annular frame 11 having a major axis in the front-rear direction of the intrauterine tissue collecting tool 1 when viewed from the front. The outer peripheral surface of the elliptical annular frame 11 (specifically, the outer surface and the front-side outer edge and the back-side outer edge when the elliptical annular frame 11 is viewed from the front) is rounded without edges. This prevents the outer peripheral surface of the tissue collecting tip 10 from damaging the inside of the uterus.

[0013] As shown in Fig. 6, the cross section of the tissue-collecting tip 10 (a cross section in a plane perpendicular to the front-rear direction of the intrauterine tissue collecting tool 1) has a substantially rectangular outer shape. Both side surfaces in the width direction (left-right direction in Fig. 6) of the tissue-collecting tip 10 are designed to have no edges. In addition, as shown in Fig. 5, the front end side surface of the tissue-collecting tip 10 is also designed to have no edges. This prevents the outer peripheral side surface of the tissue-collecting tip 10 from damaging the inside of the uterus.

[0014] The elliptical annular frame 11 of the tissue sampling tip 10 has an elliptical through hole 12 with a major axis in the front-rear direction of the intrauterine tissue sampling tool 1. In other words, the tissue sampling tip 10 has an elliptical annular shape with the elliptical through hole 12 formed in the center. As shown in Figures 5 and 6, the elliptical through hole 12 penetrates the tissue sampling tip 10 (elliptical annular frame 11) in the thickness direction (from the front to the back).

[0015] As shown in FIG. 5, the inner surface of the front end portion of the elliptical through hole 12 is a concave surface 13 extending into the elliptical annular frame 11. Specifically, the inner surface of the front end portion of the elliptical through hole 12 is concave (the hole diameter becomes larger) from both ends (front end and back end) of the elliptical through hole 12 toward the center portion. The bottom (the most recessed portion) of the concave surface 13 is preferably located near the center of the inner surface of the elliptical through hole 12. The depth of the bottom (the most recessed portion) of the concave surface 13 (the difference in height between the bottom of the concave surface 13 and the upper edge of the concave surface) is preferably about 0.2 to 2 mm, and particularly preferably 0.3 to 1.5 mm. The depth of the concave surface may not be uniform over the entire concave surface, but may vary depending on the location. The inner surface of the elliptical through hole 12 is a smooth surface or a rough surface.

[0016] In the front end portion of the elliptical annular frame 11 having the concave surface 13, the inner edges of the front and back surfaces are formed as edge portions 14, 15 that are cut inward. Specifically, as shown in FIG. 5, the connecting portions between the front portion 16 and the back portion 17 of the elliptical annular frame 11 and the concave surface 13 are formed as acute edge portions 14, 15, respectively. The angle of the edge portion (angle between the front portion 16 and the tangent line of the concave surface 13 at the edge portion 14 in FIG. 5: θ) is preferably 75° or less, and particularly preferably 30 to 65°. In this embodiment, the angles (θ) of the edge portions 14, 15 are approximately the same, but may be different angles. In that case, the edge portions 14, 15 can be used differently when collecting intrauterine tissue.

[0017] In the intrauterine tissue collecting tool 1, the front part 16 and the back part 17 of the elliptical annular frame 11 of the tissue collecting tip part 10 are provided with annular flat parts (flat surfaces approximately parallel to the front-rear direction of the intrauterine tissue collecting tool 1) formed on the periphery of the elliptical through-hole 12. In addition, by moving the intrauterine tissue collecting tool 1 toward the hand with only a part having an edge of the annular flat part [for example, the tip part (edge ​​parts 14, 15)] in contact with the inner surface of the uterus, tissue can be collected inside the tip part. In addition, by moving the intrauterine tissue collecting tool 1 laterally with only a part having an edge of the annular flat part [for example, one side part (the connecting part between the annular flat part and the elliptical through-hole 12)] in contact with the inner surface of the uterus, tissue can be collected inside the side part.

[0018] The size of the tissue sampling tip 10 (elliptical annular frame 11) and the elliptical through-hole 12 are appropriately set depending on the size and amount of the tissue to be sampled, the location of the tissue in the uterus, etc. For example, as shown in Figures 4 and 5, the front-rear dimension (long axis: La) of the elliptical through-hole 12 is preferably 10 to 25 mm, more preferably 13 to 22 mm, and more preferably 15 to 20 mm. The width dimension (short axis: Wa) of the elliptical through-hole 12 is preferably 1.5 to 6.0 mm, more preferably 1.8 to 3.5 mm, and more preferably 2.0 to 3.0 mm.

[0019] In addition, the ratio (La / Lb) of the front-rear dimension (long diameter: Lb) of the tissue sampling tip 10 (elliptical annular frame 11) to the front-rear dimension (long diameter: La) of the elliptical through-hole 12 is preferably 4 / 10 to 8 / 10, and more preferably 5 / 10 to 7 / 10. The ratio (Wa / Wb) of the width direction dimension (short diameter: Wb) of the tissue sampling tip 10 (elliptical annular frame 11) to the width direction dimension (short diameter: Wa) of the elliptical through-hole 12 is preferably 4 / 10 to 8 / 10, and more preferably 5 / 10 to 7 / 10, and more preferably 3 to 8 mm, and more preferably 4 to 7 mm. The thickness direction dimension (Tb) of the tissue sampling tip 10 (elliptical annular frame 11) is preferably 1.5 to 6.0 mm, and more preferably 2 to 5 mm.

[0020] In the intrauterine tissue sampling tool 1, as shown in Figs. 1 to 3, a shaft portion 30 extends rearward from the rear end of the tissue sampling tip portion 10.

[0021] The shaft portion 30 comprises a front end side connecting portion 32 whose cross section changes from approximately circular to approximately rectangular toward the front end, a central portion 33 connected to the front end side connecting portion 32, and a grip portion connecting portion 34 connected to the central portion 33. The central portion 33 comprises a tapered portion 35 whose cross section has an approximately circular outer shape and whose diameter decreases toward the front end.

[0022] Specifically, the front end side (tissue-collecting tip portion 10 side) of the shaft portion 30 is a front end side connecting portion 32 that is continuous with the tissue-collecting tip portion 10. The front end of the front end side connecting portion 32 and the rear end of the tissue-collecting tip portion 10 are smoothly continuous with each other.

[0023] The central portion 33 of the shaft portion 30 includes a tapered portion 35. In this embodiment, the entire central portion 33 is the tapered portion 35. Note that only a portion of the central portion may be the tapered portion (in other words, the portion of the central portion excluding the tapered portion does not have to be tapered). The front end of the central portion 33 (tapered portion 35) and the rear end of the front end side connecting portion 32 are smoothly continuous.

[0024] In this embodiment, the tapered portion 35 (central portion 33) has a substantially circular cross-sectional outer shape, with a front end having a diameter of about 2.5 mm and a rear end having a diameter of about 4.5 mm. It is preferable that the tapered portion has a front end diameter of 2 to 4 mm, a rear end diameter of 3 to 6 mm, and a difference between the front end diameter and the rear end diameter of 1 to 4 mm.

[0025] The rear end side (grip 50 side) of the shaft portion 30 is a grip portion connecting portion 34 that is continuous with the grip portion 50. The front end of the grip portion connecting portion 34 and the rear end of the central portion 33 (tapered portion 35) are smoothly continuous.

[0026] In this embodiment, the shaft portion 30 (front end connecting portion 32, central portion 33, grip connecting portion 34) has an overall front-to-rear dimension Lc (see FIG. 2) of about 125 mm. The front-to-rear dimension (Lc) of the shaft portion is preferably 100 to 150 mm. A plurality of markers (not shown) for checking the insertion depth may be provided on the outer surface of the shaft portion 30.

[0027] 1 to 3, the intrauterine tissue sampling tool 1 includes a gripping portion 50 provided at the rear end of the shaft portion 30 (grip connecting portion 34). The front end of the gripping portion 50 and the rear end of the gripping portion connecting portion 34 are smoothly connected to each other.

[0028] The gripping part 50 is formed in a long and narrow plate shape (extending in the front-rear direction of the intrauterine tissue collecting tool 1, and as shown in FIG. 7, the outer shape of the cross section is a substantially elongated rectangle) and has a front part 51 and a back part 52 which face each other and have large areas, the front part 51 of the gripping part 50 facing the same direction as the front (front part 16) of the elliptical annular frame 11 of the tissue collecting tip part 10, and the back part 52 of the gripping part 50 facing the same direction as the back (back part 17) of the elliptical annular frame 11 of the tissue collecting tip part 10. This allows an operator (doctor, etc.) handling the intrauterine tissue collecting tool 1 to know the direction of the tissue collecting tip part 10 from the direction of the gripping part 50.

[0029] The gripping portion 50 has recesses 53, 54 formed on the front portion 51 and the back portion 52, respectively. More specifically, as shown in Fig. 7, the front portion 51 and the back portion 52 have recesses 53, 54 formed toward the widthwise center, respectively. The gripping portion 50 also has a plurality of non-slip annular ribs 55 provided perpendicular to the longitudinal direction. The recesses 53, 54 and the annular ribs 55 improve the operability of the intrauterine tissue collecting tool 1.

[0030] The intrauterine tissue collecting tool 1, which includes the above-mentioned tissue collecting tip 10, shaft 30, and grip 50, is integrally formed from synthetic resin, and is formed from a material that allows the shaft to be bent by hand to form a curved section through plastic deformation. Examples of synthetic resin materials that can be used to form the intrauterine tissue collecting tool 1 include polyolefins such as polypropylene and polyethylene, fluororesins such as PTFE and ETFE, polyamide, polyesters such as PET, semi-rigid polyvinyl chloride resins, and polycarbonates. The intrauterine tissue collecting tool 1 is integrally formed as a whole, for example, by injection molding.

[0031] The intrauterine tissue collecting tool 1 of this embodiment has an overall front-rear dimension (length: L) of about 270 mm, as shown in Fig. 2. The length (L) of the intrauterine tissue collecting tool is 150 to 400 mm, preferably 220 to 350 mm.

[0032] The intrauterine tissue collecting tool 1 can be plastically deformed by manually bending the shaft portion 30 to form the curved portion 31. More specifically, as shown in Figures 8 and 9, the shaft portion 30 can be curved three-dimensionally in the width direction, thickness direction, or a suitable combination of the width direction and thickness direction, and the shape can be maintained. This allows the shape of the intrauterine tissue collecting tool 1 to be adjusted according to the shape of the uterus and the position of the intrauterine tissue to be collected within the uterus, so that the desired intrauterine tissue can be collected more reliably.

[0033] In the intrauterine tissue collecting tool 1, the cross-sectional outer shape of the central portion 33 (tapered portion 35) of the shaft portion 30 is made substantially circular. This makes it easy to bend the shaft portion 30 in any direction and into a desired shape.

[0034] In addition, the diameter of the tapered portion 35 (central portion 33) of the shaft portion 30 becomes smaller toward the front end (conversely, the diameter becomes larger toward the rear end). This allows the rear end portion of the shaft portion 30 to form and maintain a relatively gentle curved shape, while allowing the front end portion to form a relatively steep curved shape. In other words, the shape of the front end portion of the intrauterine tissue collection tool 1 (the tissue collection tip portion 10 and the shaft portion 30) to be inserted into the uterus can be formed and maintained as a whole, while the shape of the front end portion (the orientation of the tissue collection tip portion 10) of the intrauterine tissue collection tool 1 can be more finely adjusted.

[0035] Examples of intrauterine tissue to be collected using the intrauterine tissue collecting tool 1 include endometrial tissue, endometrial cells, intrauterine cells, and uterine vaginal tissue.

[0036] The intrauterine tissue collecting tool 1 has a tissue collecting tip 10 equipped with an elliptical annular frame 11 having a major axis in the front-rear direction of the intrauterine tissue collecting tool 1, the elliptical annular frame 11 equipped with an elliptical through-hole 12 having a major axis in the front-rear direction of the intrauterine tissue collecting tool 1, and further, at least the inner surface of the front end portion of the elliptical through-hole 12 is a concave surface 13 extending into the elliptical annular frame 11, and the inner edges of the front (front portion 16 side) and back (back portion 17 side) of the elliptical annular frame 11 in the portion having the concave surface 13 are edge portions 14, 15 scraped inward. As a result, the edge portions 14, 15 at the front end portion of the tissue collecting tip 10 (elliptical annular frame 11) can reliably collect the target intrauterine tissue, and the concave surface 13 in the elliptical through-hole 12 can hold the collected intrauterine tissue so that it does not fall off.

[0037] The intrauterine tissue collecting tool 1 of this embodiment is a relatively inexpensive one integrally formed from synthetic resin. Such an intrauterine tissue collecting tool 1 is sterilized and used as a disposable product. In other words, the intrauterine tissue collecting tool 1 is discarded after use and is not used by multiple patients, so there is no risk of infection between patients.

[0038] Another embodiment of the intrauterine tissue collecting tool of the present invention is shown in Figure 10. Intrauterine tissue collecting tool 1a, the shape of the tissue collecting tip is different from that of the intrauterine tissue collecting tool 1 described above. Unless otherwise specified, intrauterine tissue collecting tool 1a has substantially the same configuration as the intrauterine tissue collecting tool 1 described above, and such configuration will be given the same names and symbols (sometimes with the suffix "a" added) and detailed explanations will be omitted.

[0039] The inner surfaces of the front end portion and both sides in the minor axis direction of the elliptical through-hole 12a of the intrauterine tissue sampling device 1a are formed as concave surfaces 13, 18, 19 extending into the elliptical annular frame 11a, and the inner edges of the front and back surfaces of the elliptical annular frame 11a in the portions having the concave surfaces 13, 18, 19 are formed as inwardly scraped edges 14, 15, 21, 22, 23, 24. In other words, in the tissue-collecting tip portion 10a of the intrauterine tissue-collecting tool 1a, in addition to the front end portion of the elliptical through-hole 12a, as shown in FIG. 10, both side portions in the short diameter direction of the elliptical through-hole 12a form concave surfaces 18, 19 extending into the elliptical annular frame 11a, and the inner edges of the front and back surfaces of the elliptical annular frame 11a in the portion having the concave surface 18 form inwardly scraped edge portions 21, 22, and the inner edges of the front and back surfaces of the elliptical annular frame 11a in the portion having the concave surface 19 form inwardly scraped edge portions 23, 24.

[0040] In the intrauterine tissue collecting tool 1a, the edges 14, 15, 21, 22, 23, 24 at the front end and both short diameter sides of the tissue collecting tip 10a (elliptical ring-shaped frame 11a) allow the target intrauterine tissue to be collected more reliably, and the concave surfaces 13, 18, 19 in the elliptical through-hole 12a hold the collected intrauterine tissue so that it does not fall out. Also, compared to the intrauterine tissue collecting tool 1 described above, it is possible to collect more intrauterine tissue.

[0041] Another embodiment of the intrauterine tissue collecting tool of the present invention is shown in Fig. 11. The intrauterine tissue collecting tool 1b has a different shape of the tissue collecting tip from the intrauterine tissue collecting tools 1 and 1a described above. Unless otherwise specified, the intrauterine tissue collecting tool 1b has substantially the same configuration as the intrauterine tissue collecting tools 1 and 1a described above, and the same names and symbols (sometimes with the suffix b) are used for such configurations, and detailed explanations are omitted.

[0042] The entire inner surface of the elliptical through-hole 12b of the intrauterine tissue collecting tool 1b is a concave surface 20 extending into the elliptical annular frame 11b, and the entire inner periphery of the front and back of the elliptical annular frame 11b is an inwardly scraped edge portion 25, 26. In other words, in the tissue collecting tip portion 10b of the intrauterine tissue collecting tool 1b, in addition to the front end portion and both sides in the short diameter direction of the elliptical through-hole 12b, as shown in Fig. 11, the rear end portion of the elliptical through-hole 12b is a concave surface extending into the elliptical annular frame 11b, so that the entire inner surface of the elliptical through-hole 12b is a series of concave surfaces 20 extending into the elliptical annular frame 11b. And the entire inner periphery of the front and back of the elliptical annular frame 11b is an inwardly scraped annular edge portion 25 and 26. The angle of the edge portion (angle θ between the front portion and the tangent to the concave surface in all of the edges 14, 15, 25, and 26 in FIG. 11) is preferably 75° or less, and particularly preferably 30 to 65°.

[0043] In the intrauterine tissue collecting tool 1b, the edge portions 25, 26 ensure that the target intrauterine tissue can be collected from the entire tissue collecting tip portion 10b (elliptical annular frame 11b) (front end portion, both sides in the short diameter direction, and rear end portion), and the concave surface 20 in the elliptical through-hole 12b holds the collected intrauterine tissue so that it does not fall out. Also, compared to the intrauterine tissue collecting tools 1, 1a described above, it is possible to collect more intrauterine tissue. [Explanation of symbols]

[0044] 1,1a,1b Intrauterine tissue sampling device 10,10a,10b Tip for tissue collection 11,11a,11b Elliptical ring frame 12, 12a, 12b Elliptical through hole 13,18,19,20 concave surface 41,15,21,22,23,24,25,26 Edge section 30 Shaft section 31 Curved section 32 Front end side connection part 33 Central part 34 Grip connection part 35 Tapered section 50 Gripping part 51 Front 52 Back section 53,54 Recess 55 Circular rib

Claims

1. An intrauterine tissue sampling device having a tissue sampling tip that can be inserted into a uterus, the intrauterine tissue sampling tool comprises the tissue sampling tip portion, a shaft portion extending rearward from a rear end of the tissue sampling tip portion, and a grip portion provided at a rear end of the shaft portion; The tissue sampling tip portion has an elliptical annular frame having a major axis in the front-rear direction of the intrauterine tissue sampling tool, and the elliptical annular frame has an elliptical through hole having a major axis in the front-rear direction of the intrauterine tissue sampling tool, and further At least an inner surface of a front end portion of the elliptical through hole is a concave surface extending into the elliptical annular frame, and inner edges of the front and back surfaces of the elliptical annular frame in the portion having the concave surface are edge portions cut inward, The outer peripheral surface of the elliptical annular frame is rounded without edges, 1. The intrauterine tissue sampling tool, wherein the intrauterine tissue sampling tool is integrally formed from a synthetic resin, and the shaft portion can be manually bent to form a plastically deformed curved portion.

2. 2. The intrauterine tissue sampling device according to claim 1, wherein the inner surfaces of the front end portion and both sides in the minor axis direction of the elliptical through-hole are concave surfaces extending into the elliptical annular frame, and the inner edges of the front and back surfaces of the elliptical annular frame in the portions having the concave surfaces are formed as inwardly scraped edges.

3. 2. The intrauterine tissue sampling device according to claim 1, wherein the entire inner surface of the elliptical through hole is a concave surface extending into the elliptical annular frame, and the entire inner edges of the front and back surfaces of the elliptical annular frame are formed into inwardly scraped edges.

4. The gripping portion has a cross-sectional outer shape of a substantially elongated rectangle, 4. The intrauterine tissue sampling device according to claim 1, wherein the shaft portion comprises a front end side connecting portion whose cross section changes from a substantially circular shape to a substantially rectangular shape toward the front end, a central portion continuous with the front end side connecting portion, and a grip portion connecting portion continuous with the central portion, and the central portion comprises a tapered portion whose cross section is substantially circular and whose diameter decreases toward the front end.

5. 5. The intrauterine tissue sampling device according to claim 1, wherein the gripping portion is formed in an elongated plate shape and has a front portion and a rear portion which face each other and have a large area, the front portion of the gripping portion faces the same direction as the front of the elliptical annular frame of the tissue sampling tip portion, and the rear portion of the gripping portion faces the same direction as the rear of the elliptical annular frame of the tissue sampling tip portion.

6. 6. The intrauterine tissue sampling tool according to claim 5, wherein the gripping portion has recesses formed in the front and rear portions.

7. 7. The intrauterine tissue sampling tool according to claim 1, wherein the gripping portion is provided with a plurality of annular anti-slip ribs arranged perpendicular to the longitudinal direction.

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