Pyrimidon derivatives containing two fused bicyclic rings

Abstract

The present invention relates to compounds of formula (I), wherein the variables are as defined in the specification. The invention also relates to pesticidal mixtures comprising compounds of formula (I), the use of compounds of formula (I) as agricultural pesticides, methods for combating or controlling invertebrate pests, methods for protecting growing plants from attack or infestation by invertebrate pests, seeds comprising compounds of formula (I), the use of compounds of formula (I) to protect growing plants from attack or infestation by invertebrate pests, and methods for treating or protecting animals from infestation or infection by invertebrate pests. [Formula 1] TIFF2023502705000054.tif24142

Description

Technical Field

[0001] The present invention relates to a compound of formula (I), or an agriculturally or veterinarily acceptable salt, stereoisomer, tautomer or N-oxide thereof:

[0002]

Chemical Formula

Background Art

[0003] Invertebrate pests, particularly insects, arachnids and nematodes, damage growing and harvested crops, attack wooden houses and commercial buildings, thereby causing significant economic losses to food supplies and possessions. Therefore, there is a continuing need for new agents for controlling invertebrate pests.

[0004] EP3257853 discloses a condensed heterocyclic compound and its use as a pesticidal agent, and this compound has two condensed bicyclic moieties. WO2017 / 167832 discloses a bicyclic pyrimidinone compound and its pesticidal activity.

[0005] Since target pests can develop resistance to pesticidal agents, there is a continuing need to identify further compounds that are suitable for controlling invertebrate pests such as insects, arachnids and nematodes. Furthermore, there is a need for new compounds that have high pesticidal activity and exhibit a broad spectrum of activity against a number of different invertebrate pests, particularly insects, arachnids and nematodes which are difficult to control. SUMMARY OF THE INVENTION

[0006] Accordingly, it is an object of the present invention to identify and provide compounds that exhibit high pesticidal activity and have a broad spectrum of activity against invertebrate pests.

[0007] These objects have been found to be achievable by substituted bicyclic compounds of formula (I) as shown and defined below, including their stereoisomers, their salts, in particular their agrochemically or veterinarily acceptable salts, their tautomers and their N-oxides.

[0008] In a first aspect, the present invention provides a compound of formula (I):

[0009]

Chemical formula

[0010]

Chemical formula

[0011] The compounds of formula (I), and their agriculturally acceptable salts, are highly active against animal pests, namely harmful arthropods and nematodes, especially insects and mites which are difficult to control by other means.

[0012] Furthermore, the present invention relates to and encompasses the following embodiments: - A composition comprising at least one compound of formula (I) as defined above and a liquid or solid carrier; - An agricultural and veterinary composition comprising an amount of at least one compound of formula (I) as defined above, or their enantiomers, diastereomers or salts; - A method for controlling invertebrate pests, an attack or an infection by invertebrate pests, comprising contacting the pest or its food supply, habitat or breeding ground with a pesticidally effective amount of at least one compound of formula (I) as defined above, or a composition thereof; - A method for controlling invertebrate pests, an attack or an infection by invertebrate pests, comprising contacting the pest or its food supply, habitat or breeding ground with a pesticidally effective amount of at least one compound of formula (I) as defined above, or a composition comprising at least one compound of formula (I); - A method for preventing or protecting against invertebrate pests, comprising contacting an invertebrate pest, or its food supply, habitat or breeding ground, with a substituted imidazolium compound of general formula (I) as defined above, or a composition comprising at least one compound of formula (I) as defined above, or a composition comprising at least one compound of formula (I); - A method for protecting a crop, a plant, a plant propagation material and / or a growing plant from an attack or an infection by invertebrate pests, comprising contacting or treating the crop, the plant, the plant propagation material and the growing plant, or the soil, material, surface, space, area or water in which the crop, the plant, the plant propagation material is stored or in which the plant is growing, with a pesticidally effective amount of at least one compound of formula (I) as defined above, or a composition comprising at least one compound of formula (I); - A non-therapeutic method for treating an animal infested or infected with a parasite, or for preventing an animal that is about to be infected or attacked by a parasite, or for protecting an animal from an attack or an infection by a parasite, comprising administering or applying orally, topically or parenterally to the animal a parasitocidally effective amount of a compound of formula (I) as defined above, or a composition comprising at least one compound of formula (I); - A method for treating, controlling, preventing or protecting an animal from an infestation or infection by a parasite by orally, topically or parenterally administering or applying to the animal a compound of general formula (I) as defined above, or a composition comprising at least one compound of formula (I); - Seeds containing a compound of formula (I) as defined above in an amount of 0.1 g to 10 kg per 100 kg of seeds; - Use of a compound of formula (I) as defined above for protecting a growing plant or plant propagation material from an attack or infestation by an invertebrate pest; - Use of a compound of formula (I), or their enantiomers, diastereomers or veterinarily acceptable salts thereof, for controlling parasites in and on animals; - A method for preparing a veterinary composition for treating, controlling, preventing or protecting an animal from an infestation or infection by a parasite, comprising adding a parasiticidally effective amount of a compound of formula (I), or their enantiomers, diastereomers and / or veterinarily acceptable salts thereof, to a carrier composition suitable for veterinary use; - Use of a compound of formula (I), or their enantiomers, diastereomers and / or veterinarily acceptable salts thereof, for the preparation of a medicament for treating, controlling, preventing or protecting an animal from an infestation or infection by a parasite.

[0013] All compounds of formula (I) and, where applicable, their stereoisomers, their tautomers, their salts or their N-oxides and their compositions are particularly useful for controlling invertebrate pests, especially for controlling arthropods and nematodes, particularly insects. Accordingly, the present invention relates to the use of a compound of formula (I) as an agrochemical pesticidal agent for controlling preferably invertebrate pests, particularly invertebrate pests of the group of insects, arachnids or nematodes.

[0014] As used herein, the term "compound(s) according to the invention" or "compound(s) of formula (I)" refers to and includes the compound(s) defined herein, and / or their stereoisomer(s), salt(s), tautomer(s), or N-oxide(s). The term "compound(s) of the invention" is understood to be equivalent to the term "compound(s) according to the invention" and thus also includes the stereoisomer(s), salt(s), tautomer(s), or N-oxide(s) of the compound of formula (I).

[0015] The term "composition(s) according to the invention" or "composition(s) of the invention" encompasses a composition(s) comprising at least one compound of formula (I) according to the invention as defined above and thus also includes the stereoisomers, agriculturally or veterinarily acceptable salts, tautomers or N-oxides of the compound of formula (I).

[0016] The compounds of the invention may be amorphous or may exist in one or more different crystalline forms (polymorphs) or variants which may have different macroscopic properties (such as stability) or may exhibit different biological properties (such as activity). The invention includes both amorphous and crystalline compounds of formula (I), mixtures of each compound I in different crystalline forms or variants, and their amorphous or crystalline salts.

[0017] The compounds of formula (I) may have one or, depending on the substitution pattern, two or more chiral centers, in which case these compounds exist as mixtures of enantiomers or diastereomers. The present invention provides both the single pure enantiomers or pure diastereomers of the compounds of formula (I), and mixtures thereof, and the use according to the invention of the pure enantiomers or pure diastereomers of the compounds of formula (I), or mixtures thereof. Suitable compounds of formula (I) also include all possible geometric stereoisomers (cis / trans isomers) and mixtures thereof. Cis / trans isomers may exist with respect to alkenes, carbon-nitrogen double bonds or amide groups. The term "stereoisomer(s)" encompasses both optical isomers such as enantiomers or diastereomers (the latter being present due to two or more chiral centers in the molecule) and geometric isomers (cis / trans isomers). The present invention relates to all possible stereoisomers of the compounds of formula (I), i.e., single enantiomers or diastereomers, and mixtures thereof.

[0018] Depending on the substitution pattern, the compounds of formula (I) may exist in their tautomeric forms. Accordingly, the present invention also relates to the tautomers of formula (I), and to the stereoisomers, salts, tautomers and N-oxides of said tautomers.

[0019] The salts of the compounds of formula (I) are preferably agriculturally and / or veterinarily acceptable salts. These can be formed in conventional manner, for example, by reacting the compound of formula (I) with an acid of the appropriate anion when the compound has a basic functional group, or by reacting an acidic compound of formula (I) with a suitable base.

[0020] Suitable agriculturally or veterinarily useful salts are, inter alia, salts of these cations or acid addition salts of these acids, in which their cations and anions, respectively, have no adverse effects on the action of the compounds according to the invention. Suitable cations are, in particular, ions of alkali metals (preferably lithium, sodium and potassium), ions of alkaline earth metals (preferably calcium, magnesium and barium), and ions of transition metals (preferably manganese, copper, zinc and iron), and also ammonium (NH4 + ) and substituted ammonium, where 1 to 4 hydrogen atoms are substituted by C1-C4-alkyl, C1-C4-hydroxyalkyl, C1-C4-alkoxy, C1-C4-alkoxy-C1-C4-alkyl, hydroxy-C1-C4-alkoxy-C1-C4-alkyl, phenyl or benzyl. Examples of substituted ammonium ions are methylammonium, isopropylammonium, dimethylammonium, diisopropylammonium, trimethylammonium, tetramethylammonium, tetraethylammonium, tetrabutylammonium, 2-hydroxyethylammonium, 2-(2-hydroxyethoxy)ethyl-ammonium, bis(2-hydroxyethyl)ammonium, benzyltrimethylammonium and benzyltriethylammonium, and also phosphonium ions, sulfonium ions, preferably tri(C1-C4-alkyl)sulfonium, and sulfoxonium ions, preferably tri(C1-C4-alkyl)sulfoxonium.

[0021] Anions of useful acid addition salts are mainly chloride ions, bromide ions, fluoride ions, hydrogen sulfate ions, sulfate ions, dihydrogen phosphate ions, hydrogen phosphate ions, phosphate ions, nitrate ions, hydrogen carbonate ions, carbonate ions, hexafluorosilicate ions, hexafluorophosphate ions, benzoate ions, and anions of C1-C4-alkanoic acids, preferably formate ions, acetate ions, propionate ions and butyrate ions. They can be formed by reacting the compound of formula I with an acid of the corresponding anion, preferably hydrochloric acid, hydrobromic acid, sulfuric acid, phosphoric acid or nitric acid.

[0022] The term "N-oxide" encompasses any compound of the invention having at least one tertiary nitrogen atom oxidized in the N-oxide moiety.

[0023] The groups of the organic moieties referred to in the definitions of the above variable elements are, like the term "halogen", a collective term for the individual lists of the individual radicals. The prefix C n -C m in each case indicates the possible number of carbon atoms in the group. "Halogen" is understood to mean F, Cl, Br, and I, preferably F.

[0024] For example, the term "substituted with" as used in "substituted in part or completely with" means that one or more (e.g., 1, 2, 3, 4, or 5) or all of the hydrogen atoms of a given group are substituted with one or more of the same or different substituents, such as halogen, especially F. Thus, in a substituted cyclic moiety, such as 1-cyanocyclopropyl, one or more of the hydrogen atoms of the cyclic moiety may be substituted with one or more of the same or different substituents.

[0025] The term "C n -C m -alkyl" (as well as C n -C m -alkylamino, di-C n -C m -alkylamino, C n -C m -alkylaminocarbonyl, di-(C n -C m -alkylamino)carbonyl, C n -C m -alkylthio, C n -C m -alkylsulfinyl and C n -C m- The same applies to -alkylsulfonyl), which has n to m, for example 1 to 10, preferably 1 to 6 carbon atoms, and is a branched or unbranched saturated hydrocarbon group such as methyl, ethyl, propyl, 1-methylethyl, butyl, 1-methylpropyl, 2-methylpropyl, 1,1-dimethylethyl, pentyl, 1-methylbutyl, 2-methylbutyl, 3-methylbutyl, 2,2-dimethylpropyl, 1-ethylpropyl, hexyl, 1,1-dimethylpropyl, 1,2-dimethylpropyl, 1-methylpentyl, 2-methylpentyl, 3-methylpentyl, 4-methylpentyl, 1,1-dimethylbutyl, 1,2-dimethylbutyl, 1,3-dimethylbutyl, 2,2-dimethylbutyl, 2,3-dimethylbutyl, 3,3-dimethylbutyl, 1-ethylbutyl, 2-ethylbutyl, 1,1,2-trimethylpropyl, 1,2,2-trimethylpropyl, 1-ethyl-1-methylpropyl, 1-ethyl-2-methylpropyl, heptyl, octyl, 2-ethylhexyl, nonyl and decyl and their isomers. C1-C4-alkyl means, for example, methyl, ethyl, propyl, 1-methylethyl, butyl, 1-methylpropyl, 2-methylpropyl, or 1,1-dimethylethyl.

[0026] As used herein, the term "C n -C m -haloalkyl" (as well as C n -C m -haloalkylsulfinyl and C n -C m-The same applies to haloalkylsulfonyl) is a linear or branched alkyl group having n to m carbon atoms, for example 1 to 10 carbon atoms, especially 1 to 6 carbon atoms (as described above), wherein some or all of the hydrogen atoms in these groups may be substituted with the above halogen atoms, for example C1-C4-haloalkyl, such as chloromethyl, bromomethyl, dichloromethyl, trichloromethyl, fluoromethyl, difluoromethyl, trifluoromethyl, chlorofluoromethyl, dichlorofluoromethyl, chlorodifluoromethyl, 1-chloroethyl, 1-bromoethyl, 1-fluoroethyl, 2-fluoroethyl, 2,2-difluoroethyl, 2,2,2-trifluoroethyl, 2-chloro-2-fluoroethyl, 2-chloro-2,2-difluoroethyl, 2,2-dichloro-2-fluoroethyl, 2,2,2-trichloroethyl, pentafluoroethyl and the like. The term "C1-C 10 -haloalkyl" particularly includes C1-C2-fluoroalkyl (which is synonymous with methyl or ethyl in which 1, 2, 3, 4 or 5 hydrogen atoms are substituted with fluorine atoms), such as fluoromethyl, difluoromethyl, trifluoromethyl, 1-fluoroethyl, 2-fluoroethyl, 2,2-difluoroethyl, 2,2,2-trifluoroethyl and pentafluoroethyl.

[0027] Similarly, "C n -C m -alkoxy" and "C n -C m -alkylthio" (or C n -C m -alkylsulfenyl, respectively) refers to a linear or branched alkyl group having n to m carbon atoms, for example 1 to 10 carbon atoms, especially 1 to 6 or 1 to 4 carbon atoms (as described above) bonded through an oxygen (or sulfur bond, respectively) at any bond in the alkyl group. Examples include C1-C4-alkoxy, such as methoxy, ethoxy, propoxy, isopropoxy, butoxy, sec-butoxy, isobutoxy and tert-butoxy, and further C1-C4-alkylthio, such as methylthio, ethylthio, propylthio, isopropylthio, and n-butylthio and the like.

[0028] Thus, the term "C" n -C m -haloalkoxy" and "C" n -C m -haloalkylthio" (or C n -C m- Haloalkylsulfenyl, respectively) is a straight-chain or branched alkyl group having n to m carbon atoms, for example 1 to 10 carbon atoms, particularly 1 to 6 carbon atoms or 1 to 4 carbon atoms, bonded through an oxygen or sulfur bond, respectively, at any bond in the alkyl group (as described above), and some or all of the hydrogen atoms in these groups may be substituted with the above halogen atoms, for example, C1-C2-haloalkoxy, such as chloromethoxy, bromomethoxy, dichloromethoxy, trichloromethoxy, fluoromethoxy, difluoromethoxy, trifluoromethoxy, chlorofluoromethoxy, dichlorofluoromethoxy, chlorodifluoromethoxy, 1-chloroethoxy, 1-bromoethoxy, 1-fluoroethoxy, 2-fluoroethoxy, 2,2-difluoroethoxy, 2,2,2-trifluoroethoxy, 2-chloro-2-fluoroethoxy, 2-chloro-2,2-difluoroethoxy, 2,2-dichloro-2-fluoroethoxy, 2,2,2-trichloroethoxy and pentafluoroethoxy, and further C1-C2-haloalkylthio, such as chloromethylthio, bromomethylthio, dichloromethylthio, trichloromethylthio, fluoromethylthio, difluoromethylthio, trifluoromethylthio, chlorofluoromethylthio, dichlorofluoromethylthio, chlorodifluoromethylthio, 1-chloroethylthio, 1-bromoethylthio, 1-fluoroethylthio, 2-fluoroethylthio, 2,2-difluoroethylthio, 2,2,2-trifluoroethylthio, 2-chloro-2-fluoroethylthio, 2-chloro-2,2-difluoroethylthio, 2,2-dichloro-2-fluoroethylthio, 2,2,2-trichloroethylthio and pentafluoroethylthio, etc. Similarly, the terms "C1-C2-fluoroalkoxy" and "C1-C2-fluoroalkylthio" refer to C1-C2-fluoroalkyl bonded through an oxygen atom or a sulfur atom, respectively, to the rest of the molecule.

[0029] The term "C2-C m"-alkenyl" means a branched or unbranched unsaturated hydrocarbon group having 2 to m, for example 2 to 10 or 2 to 6 carbon atoms and a double bond at any position, such as ethenyl, 1-propenyl, 2-propenyl, 1-methyl-ethenyl, 1-butenyl, 2-butenyl, 3-butenyl, 1-methyl-1-propenyl, 2-methyl-1-propenyl, 1-methyl-2-propenyl, 2-methyl-2-propenyl, 1-pentenyl, 2-pentenyl, 3-pentenyl, 4-pentenyl, 1-methyl-1-butenyl, 2-methyl-1-butenyl, 3-methyl-1-butenyl, 1-methyl-2-butenyl, 2-methyl-2-butenyl, 3-methyl-2-butenyl, 1-methyl-3-butenyl, 2-methyl-3-butenyl, 3-methyl-3-butenyl, 1,1-dimethyl-2-propenyl, 1,2-dimethyl-1-propenyl, 1,2-dimethyl-2-propenyl, 1-ethyl-1-propenyl, 1-ethyl-2-propenyl, 1-hexenyl, 2-hexenyl, 3-hexenyl, 4-hexenyl, 5-hexenyl, 1-methyl-1-pentenyl, 2-methyl-1-pentenyl, 3-methyl-1-pentenyl, 4-methyl-1-pentenyl, 1-methyl-2-pentenyl, 2-methyl-2-pentenyl, 3-methyl-2-pentenyl, 4-methyl-2-pentenyl, 1-methyl-3-pentenyl, 2-methyl-3-pentenyl, 3-methyl-3-pentenyl, 4-methyl-3-pentenyl, 1-methyl-4-pentenyl, 2-methyl-4-pentenyl, 3-methyl-4-pentenyl, 4-methyl-4-pentenyl, 1,1-dimethyl-2-butenyl, 1,1-dimethyl-3-butenyl, 1,2-dimethyl-1-butenyl, 1,2-dimethyl-2-butenyl, 1,2-dimethyl-3-butenyl, 1,3-dimethyl-1-butenyl, 1,3-dimethyl-2-butenyl, 1,3-dimethyl-3-butenyl, 2,2-dimethyl-3-butenyl, 2,3-dimethyl-1-butenyl, 2,3-dimethyl-2-butenyl, 2,3-dimethyl-3-butenyl, 3,3-dimethyl-1-butenyl, 3,3-dimethyl-2-butenyl, 1-ethyl-1-butenyl, 1-ethyl-2-butenyl, 1-ethyl-3-butenyl, 2-ethyl-1-butenyl, 2-ethyl-2-butenyl, 2-ethyl-3-butenyl, 1,1,2-trimethyl-2-propenyl, 1-ethyl-1-methyl-2-propenyl, 1-ethyl-2-methyl-1-propenyl and 1-ethyl-2-methyl-2-propenyl are intended.,

[0030] As used herein, the term "C2-C m -alkynyl" refers to a branched or unbranched unsaturated hydrocarbon group having 2 to m, for example 2 to 10 or 2 to 6 carbon atoms and containing at least one triple bond, such as ethynyl, propynyl, 1-butynyl, 2-butynyl, etc.

[0031] As used herein, the term "C n -C m -alkoxy-C n -C m -alkyl" refers to an alkyl having n to m carbon atoms, such as those in the above specific examples, wherein one hydrogen atom of the alkyl group is replaced by a C n -C m -alkoxy group, and the values of n and m of the alkoxy group are independently selected from the values of n and m of the alkyl group.

[0032] The suffix "-carbonyl" or "C(=O)" in the group indicates in each case that the group is attached to the remainder of the molecule via a carbonyl C=O group. This is the case, for example, for alkylcarbonyl, haloalkylcarbonyl, aminocarbonyl, alkylaminocarbonyl, dialkylaminocarbonyl, alkoxycarbonyl, haloalkoxycarbonyl.

[0033] As used herein, the term "aryl" refers to a monocyclic, bicyclic or tricyclic aromatic hydrocarbon group, such as phenyl or naphthyl, particularly phenyl (also referred to as C6H5 as a substituent).

[0034] As used herein, the term "C3-C m"-Cycloalkyl" refers to a monocyclic ring of a 3- to m-membered saturated alicyclic group, for example, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, cycloheptyl, cyclooctyl, and cyclodecyl.

[0035] The term "alkylcycloalkyl" indicates an alkyl group substituted with a cycloalkyl ring, similar to the term "alkyl optionally substituted with cycloalkyl" (alkyl and cycloalkyl are as defined herein).

[0036] The term "cycloalkylalkyl" indicates a cycloalkyl ring substituted with an alkyl group, similar to the term "cycloalkyl optionally substituted with alkyl" (alkyl and cycloalkyl are as defined herein).

[0037] The term "alkylcycloalkylalkyl" indicates an alkylcycloalkyl group substituted with an alkyl group, similar to the term "alkylcycloalkyl optionally substituted with alkyl" (alkyl and alkylcycloalkyl are as defined herein).

[0038] The term "C3-C m -cycloalkenyl" used herein refers to a monocyclic ring of a 3- to m-membered partially unsaturated alicyclic group.

[0039] The term "cycloalkylcycloalkyl" is, like the term "cycloalkyl optionally substituted with cycloalkyl", a cycloalkyl substituent on another cycloalkyl ring, where each cycloalkyl ring independently has ring members of 3 to 7 carbon atoms, and the cycloalkyls are bonded via one single bond or have one common carbon atom. Examples of cycloalkylcycloalkyl include cyclopropylcyclopropyl (e.g., 1,1'-bicyclopropyl-2-yl), cyclohexylcyclohexyl where the two rings are linked through one common carbon atom (e.g., 1,1'-bicyclohexyl-2-yl), cyclohexylcyclopentyl where the two rings are linked through one single bond (e.g., 4-cyclopentylcyclohexyl), and their different stereoisomers, such as (1R,2S)-1,1'-bicyclopropyl-2-yl and (1R,2R)-1,1'-bicyclopropyl-2-yl. The term "carbocyclic" or "carbocyclic ring" generally includes, unless otherwise indicated, a 3- to 12-membered, preferably 3- to 8-membered or 5- to 8-membered, more preferably 5- or 6-membered monocyclic ring containing 3 to 12, preferably 3 to 8 or 5 to 8, more preferably 5 or 6 carbon atoms.

[0040] The carbocyclic group may be saturated, partially unsaturated, or fully unsaturated. Preferably, the term "carbocyclic ring" includes the cycloalkyl groups and cycloalkenyl groups defined above, such as cyclopropane, cyclobutane, cyclopentane, and cyclohexane rings. When referring to a "fully unsaturated" carbocyclic ring, this term also includes an "aromatic" carbocyclic ring. In certain preferred embodiments, the fully unsaturated carbocyclic ring is an aromatic carbocyclic ring as defined below, preferably a 6-membered aromatic carbocyclic ring.

[0041] The term "heteraryl" or "aromatic heterocyclic ring" or "aromatic heterocyclic ring system" includes monocyclic 5- or 6-membered heteroaromatic groups containing 1, 2, 3 or 4 heteroatoms selected from N, O and S as ring members. Examples of 5- or 6-membered heteroaromatic groups include pyridyl (i.e., 2-, 3- or 4-pyridyl), pyrimidinyl (i.e., 2-, 4- or 5-pyrimidinyl), pyrazinyl, pyridazinyl (i.e., 3- or 4-pyridazinyl), thienyl (i.e., 2- or 3-thienyl), furyl (i.e., 2- or 3-furyl), pyrrolyl (i.e., 2- or 3-pyrrolyl), oxazolyl (i.e., 2-, 3- or 5-oxazolyl), isoxazolyl (i.e., 3-, 4- or 5-isoxazolyl), thiazolyl (i.e., 2-, 3- or 5-thiazolyl), isothiazolyl (i.e., 3-, 4- or 5-isothiazolyl), pyrazolyl (i.e., 1-, 3-, 4- or 5-pyrazolyl), (i.e., 1-, 2-, 4- or 5-imidazolyl), oxadiazolyl, for example 2- or 5-[1,3,4]oxadiazolyl, 4- or 5-(1,2,3-oxadiazol)yl, 3- or 5-(1,2,4-oxadiazol)yl, 2- or 5-(1,3,4-thiadiazol)yl, thiadiazolyl, for example 2- or 5-(1,3,4-thiadiazol)yl, 4- or 5-(1,2,3-thiadiazol)yl, 3- or 5-(1,2,4-thiadiazol)yl, triazolyl, for example 1H-, 2H- or 3H-1,2,3-triazol-4-yl, 2H-triazol-3-yl, 1H, 2H or 4H-1,2,4-triazolyl and tetrazolyl (i.e., 1H- or 2H-tetrazolyl). Further, the term "heteraryl" is a bicyclic 8- to 10-membered heteroaromatic group containing 1, 2 or 3 heteroatoms selected from N, O and S as ring members, and includes those in which a 5- or 6-membered heteroaromatic ring is condensed with a phenyl ring or a 5- or 6-membered heteroaromatic group. Examples of the 5- or 6-membered heteroaromatic ring condensed with a phenyl ring or a 5- or 6-membered heteroaromatic group include benzofuranyl, benzothienyl, indolyl, indazolyl, benzimidazolyl, benzoxathiazolyl, benzoxadiazolyl, benzothiadiazolyl, benzoxazinyl, quinolinyl, isoquinolinyl, purinyl, 1,8-naphthyridyl, pteridyl, pyrido Examples include 3,2-d]pyrimidyl or pyridoimidazolyl. These fused heteroaryl groups may be attached to the remainder of the molecule via any ring atom of a 5- or 6-membered heteroaromatic ring or via a carbon atom of the fused phenyl moiety.

[0042] The terms "heterocyclic ring", "heterocyclyl" or "heterocyclic ring system", unless otherwise indicated, generally include monocyclic heterocyclic ring groups having 3 to 12 members, preferably 3 to 8 members, 3 to 7 members, or 5 to 8 members, more preferably 5 or 6 members, and particularly 6 members. The heterocyclic ring group may be saturated, partially unsaturated, or fully unsaturated. The term "fully unsaturated" as used in this context includes "aromatic". In a preferred embodiment, the fully unsaturated heterocyclic ring is thus an aromatic heterocyclic ring, preferably a 5- or 6-membered aromatic heterocyclic ring containing one or more, for example 1, 2, 3 or 4, preferably 1, 2 or 3, heteroatoms selected from N, O and S as ring members. Examples of aromatic heterocyclic rings are listed above in connection with the definition of "heteroaryl". Thus, unless otherwise indicated, "heteroaryl" is included in the term "heterocyclic ring". Heterocyclic non-aromatic groups usually contain 1, 2, 3, 4 or 5, preferably 1, 2 or 3, heteroatoms selected from N, O and S as ring members, and the S atom as a ring member may be present as S, SO or SO2. Examples of 5- or 6-membered heterocyclic ring groups include saturated or unsaturated non-aromatic heterocyclic rings, such as oxiranyl, oxetanyl, thietanyl, thietanyl-S-oxide (S-oxothietanyl), thietanyl-S-dioxide (S-dioxothietanyl), pyrrolidinyl, pyrrolinyl, pyrazolinyl, tetrahydrofuranyl, dihydrofuranyl, 1,3-dioxolanyl, thiolanyl, S-oxothiolanyl, S-dioxothiolanyl, dihydrothienyl, S-oxodihydrothienyl, S-dioxodihydrothienyl, oxazolidinyl, oxazolinyl, thiazolinyl, oxathiolanyl, piperidinyl, piperazinyl, pyranyl, dihydropyranyl, tetrahydropyranyl, 1,3- and 1,4-dioxanyl, thiopyranyl, S-oxothiopyranyl, S-dioxothiopyranyl, dihydrothiopyranyl, S-oxodihydrothiopyranyl, S-dioxodihydrothiopyranyl, tetrahydrothiopyranyl, S-oxotetrahydrothiopyranyl, S-dioxotetrahydrothiopyranyl, morpholinyl, thiomorpholinyl, S-oxothiomorpholinyl, S-dioxothiomorpholinyl, thiazinyl, etc.Examples of heterocyclic rings containing also one or two carbonyl groups as ring members include pyrrolidin-2-yl, pyrrolidine-2,5-dione, imidazolidin-2-yl, oxazolidin-2-yl, thiazolidin-2-yl and the like.

[0043] The terms "alkylene", "alkenylene" and "alkynylene" refer to alkyl, alkenyl and alkynyl as defined above, respectively, which represent a linker between two parts of a molecule by being bonded to the remainder of the molecule through two atoms of each group, preferably through two carbon atoms. In particular, the term "alkylene" may refer to alkyl chains such as CH2CH2, -CH(CH3)-, CH2CH2CH2, CH(CH3)CH2, CH2CH(CH3), CH2CH2CH2CH2, CH2CH2CH2CH2CH2, CH2CH2CH2CH2CH2CH2, and CH2CH2CH2CH2CH2CH2CH2. Similarly, "alkenylene" and "alkynylene" may refer to alkenyl chains and alkynyl chains, respectively.

[0044] As used herein, the term "5- to 6-membered carbocyclic ring" refers to a cyclopentane ring and a cyclohexane ring.

[0045] Examples of 5- or 6-membered saturated heterocyclic rings include 2-tetrahydrofuranyl, 3-tetrahydrofuranyl, 2-tetrahydrothienyl, 3-tetrahydrothienyl, 2-pyrrolidinyl, 3-pyrrolidinyl, 3-pyrazolidinyl, 4-pyrazolidinyl, 5-pyrazolidinyl, 2-imidazolidinyl, 4-imidazolidinyl, 2-oxazolidinyl, 4-oxazolidinyl, 5-oxazolidinyl, 3-isoxazolidinyl, 4-isoxazolidinyl, 5-isoxazolidinyl, 2-thiazolidinyl, 4-thiazolidinyl, 5-thiazolidinyl, 3-isothiazolidinyl, 4-isothiazolidinyl, 5-isothiazolidinyl, 1,2,4-oxadiazolidin-3-yl, 1,2,4-oxadiazolidin-5-yl, 1,2,4-thiadiazolidin-3-yl, 1,2,4-thiadiazolidin-5-yl, 1,2,4-triazolidin-3-yl, -1,3,4-oxadiazolidin-2-yl, 1,3,4-thiadiazolidin-2-yl, 1,3,4-triazolidin-2-yl, 2-tetrahydropyranyl, 4-tetrahydropyranyl, 1,3-dioxan-5-yl, 1,4-dioxan-2-yl, 2-piperidinyl, 3-piperidinyl, 4-piperidinyl, 3-hexahydropyridazinyl, 4-hexahydropyridazinyl, 2-hexahydropyrimidinyl, 4-hexahydropyrimidinyl, 5-hexahydropyrimidinyl, 2-piperazinyl, 1,3,5-hexahydrotriazin-2-yl and 1,2,4-hexahydrotriazin-3-yl, 2-morpholinyl, 3-morpholinyl, 2-thiomorpholinyl, 3-thiomorpholinyl, 1-oxothiomorpholin-2-yl, 1-oxothiomorpholin-3-yl, 1,1-dioxothiomorpholin-2-yl, 1,1-dioxothiomorpholin-3-yl.

[0046] Examples of 5- or 6-membered partially unsaturated heterocyclyl or heteroaryl rings include: 2,3-dihydrofuran-2-yl, 2,3-dihydrofuran-3-yl, 2,4-dihydrofuran-2-yl, 2,4-dihydrofuran-3-yl, 2,3-dihydrothien-2-yl, 2,3-dihydrothien-3-yl, 2,4-dihydrothien-2-yl, 2,4-dihydrothien-3-yl, 2-pyrrolin-2-yl, 2-pyrrolin-3-yl, 3-pyrrolin-2-yl, 3-pyrrolin-3-yl, 2-isoxazolin-3-yl, 3-isoxazolin-3-yl, 4-isoxazolin-3-yl, 2-isoxazolin-4-yl, 3-isoxazolin-4-yl, 4-isoxazolin-4-yl, 2-isoxazolin-5-yl, 3-isoxazolin-5-yl, 4-isoxazolin-5-yl, 2-isothiazolin-3-yl, 3-isothiazolin-3-yl, 4-isothiazolin-3-yl, 2-isothiazolin-4-yl, 3-isothiazolin-4-yl, 4-isothiazolin-4-yl, 2-isothiazolin-5-yl, 3-isothiazolin-5-yl, 4-isothiazolin-5-yl, 2,3-dihydropyrazol-1-yl, 2,3-dihydropyrazol-2-yl, 2,3-dihydropyrazol-3-yl, 2,3-dihydropyrazol-4-yl, 2,3-dihydropyrazol-5-yl, 3,4-dihydropyrazol-1-yl, 3,4-dihydropyrazol-3-yl, 3,4-dihydropyrazol-4-yl, 3,4-dihydropyrazol-5-yl, 4,5-dihydropyrazol-1-yl, 4,5-dihydropyrazol-3-yl, 4,5-dihydropyrazol-4-yl, 4,5-dihydropyrazol-5-yl, 2,3-dihydrooxazol-2-yl, 2,3-dihydrooxazol-3-yl, 2,3-dihydrooxazol-4-yl, 2,3-dihydrooxazol-5-yl, 3,4-dihydrooxazol-2-yl, 3,4-dihydrooxazol-3-yl, 3,4-dihydrooxazol-4-yl, 3,4-dihydrooxazol-5-yl, 3,4-dihydrooxazol-2-yl, 3,4-dihydrooxazol-3-yl, 3,4-dihydrooxazol-4-yl, 2-, 3-, 4-, 5- or 6-di- or tetrahydropyridinyl, 3-di- or tetrahydropyridazinyl, 4-di- or tetrahydropyridazinyl, 2-di- or tetrahydropyrimidinyl, 4-di- or tetrahydropyrimidinyl, 5-di- or tetrahydropyrimidinyl, di- or tetrahydropyrazinyl, 1,3,5-di- or tetrahydrotriazin-2-yl and the like can be mentioned.,

[0047] Examples of 5- or 6-membered fully unsaturated heterocyclic (heteroaryl) or heteroaromatic rings are: 2-furyl, 3-furyl, 2-thienyl, 3-thienyl, 2-pyrrolyl, 3-pyrrolyl, 3-pyrazolyl, 4-pyrazolyl, 5-pyrazolyl, 2-oxazolyl, 4-oxazolyl, 5-oxazolyl, 2-thiazolyl, 4-thiazolyl, 5-thiazolyl, 2-imidazolyl, 4-imidazolyl, 1,3,4-triazol-2-yl, 2-pyridinyl, 3-pyridinyl, 4-pyridinyl, 3-pyridazinyl, 4-pyridazinyl, 2-pyrimidinyl, 4-pyrimidinyl, 5-pyrimidinyl and 2-pyrazinyl.

[0048] “C2-C m -alkylene” is a divalent branched or preferably unbranched saturated aliphatic chain having 2 to m carbon atoms, for example 2 to 7 carbon atoms, such as CH2CH2, -CH(CH3)-, CH2CH2CH2, CH(CH3)CH2, CH2CH(CH3), CH2CH2CH2CH2, CH2CH2CH2CH2CH2, CH2CH2CH2CH2CH2CH2, and CH2CH2CH2CH2CH2CH2CH2.

[0049] As used herein, the term “alkylamino” refers to a straight-chain or branched saturated alkyl group having 1 to 10 carbon atoms, preferably 1 to 4 carbon atoms, more preferably 1 to 3 carbon atoms, bonded through a nitrogen atom, such as an -NH- group.

[0050] As used herein, the term "dialkylamino" refers to a straight-chain or branched saturated alkyl group having 1 to 10 carbon atoms, preferably 1 to 4 carbon atoms, more preferably 1 to 3 carbon atoms, which is substituted by another straight-chain or branched saturated alkyl group having 1 to 10 carbon atoms, preferably 1 to 4 carbon atoms, more preferably 1 to 3 carbon atoms, and is bonded through a nitrogen atom, such as a methylamino group or an ethylamino group.

[0051] As used herein, the term "alkylthio" (alkylsulfanyl: alkyl-S-) refers to a straight-chain or branched saturated alkyl group having 1 to 10 carbon atoms, preferably 1 to 4 carbon atoms (=C1-C4-alkylthio), more preferably 1 to 3 carbon atoms, which is bonded through a sulfur atom. Examples include methylthio, ethylthio, propylthio, isopropylthio, and n-butylthio.

[0052] As used herein, the term "haloalkylthio" refers to the above alkylthio group in which a hydrogen atom is partially or completely substituted by fluorine, chlorine, bromine, and / or iodine. Examples include chloromethylthio, bromomethylthio, dichloromethylthio, trichloromethylthio, fluoromethylthio, difluoromethylthio, trifluoromethylthio, chlorofluoromethylthio, dichlorofluoromethylthio, chlorodifluoromethylthio, 1-chloroethylthio, 1-bromoethylthio, 1-fluoroethylthio, 2-fluoroethylthio, 2,2-difluoroethylthio, 2,2,2-trifluoroethylthio, 2-chloro-2-fluoroethylthio, 2-chloro-2,2-difluoroethylthio, 2,2-dichloro-2-fluoroethylthio, 2,2,2-trichloroethylthio, and pentafluoroethylthio.

[0053] As used herein, the term "alkylsulfinyl" (alkylsulfoxyl: C1-C6-alkyl-S(=O)-) refers to a straight-chain or branched saturated alkyl group having 1 to 10 carbon atoms, preferably 1 to 4 carbon atoms (=C1-C4-alkylsulfinyl), more preferably 1 to 3 carbon atoms, which is bonded via the sulfur atom of the sulfinyl group at any position in the alkyl group.

[0054] As used herein, the term "alkylsulfonyl" (alkyl-S(=O)2-) refers to a straight-chain or branched saturated alkyl group having 1 to 10 carbon atoms, preferably 1 to 4 carbon atoms (=C1-C4-alkylsulfonyl), preferably 1 to 3 carbon atoms, which is bonded via the sulfur atom of the sulfonyl group at any position in the alkyl group.

[0055] The term "alkylcarbonyl" (C1-C6-C(=O)-) refers to a straight-chain or branched alkyl group as defined above, which is bonded to the remainder of the molecule via the carbon atom of the carbonyl group (C=O).

[0056] The term "alkoxycarbonyl" refers to an alkoxy group as defined above, which is bonded to the remainder of the molecule via the carbon atom of the carbonyl group (C=O).

[0057] The term "alkylaminocarbonyl" (C1-C6-NH-C(=O)-) refers to a straight-chain or branched alkylamino group as defined above, which is bonded to the remainder of the molecule via the carbon atom of the carbonyl group (C=O). Similarly, the term "dialkylaminocarbonyl" refers to a straight-chain or branched saturated alkyl group as defined above, which is bonded to the nitrogen atom and is substituted by another straight-chain or branched saturated alkyl group as defined above, and then the nitrogen atom is bonded to the remainder of the molecule via the carbonyl group (C=O).

[0058] Preparation method The compounds of formula (I) can be prepared by standard methods of organic chemistry. If certain derivatives cannot be prepared by the methods outlined below, they can be obtained by derivatization of other compounds of formula (I) available by these methods.

[0059] Preparation methods that are generally useful for the preparation of the compounds of formula (I) are disclosed in EP3257853A1, particularly pages 33 - 57 and the experimental section, and WO2017 / 167832A1, particularly pages 4 - 6 and the experimental section.

[0060] Compounds of formula (II) corresponding to compounds of formula (I) where Q is C(R 6 ) can be prepared by reacting a compound of formula (1) with a compound of formula (2) as shown in Process 1.

[0061]

Chemical formula

[0062] All variable elements in formulas (1), (2), and (II) have the meanings defined for formula (I). The compounds of formula (1) and the compounds of formula (2) are typically reacted with each other in equimolar amounts. In terms of yield, it may be advantageous to use an excess of the compound of formula (2). This type of reaction is described in EP3257853A1, pages 33 - 34. The reaction is typically carried out at a high temperature of 50 - 160 °C in an inert solvent. Suitable solvents are aliphatic hydrocarbons such as pentane, hexane, cyclohexane, or petroleum ether; aromatic hydrocarbons such as benzene, toluene, o -, m -, and p - xylene; halogenated hydrocarbons, or halogenated aromatic C6 - C 10Hydrocarbons such as CH2Cl2, CHCl3, CCl4, CH2ClCH2Cl, CCl3CH3, CHCl2CH2Cl, CCl2CCl2, or chlorobenzene; ethers such as CH3CH2OCH2CH3, (CH3)2CHOCH(CH3)2, CH3OC(CH3)3 (MTBE), CH3OCH3 (DME), CH3OCH2CH2OCH3, CH3OC(CH3)2CH2CH3, dioxane, anisole, 2-methyltetrahydrofuran, tetrahydrofuran (THF), and diethylene glycol; nitriles such as CH3CN and CH3CH2CN; alcohols such as CH3OH, CH3CH2OH, CH3CH2CH2OH, CH3CH(OH)CH3, CH3(CH2)3OH, and C(CH3)3OH, CH2(OH)CH2(OH), CH3CH(OH)CH2OH; amides and urea derivatives such as dimethylformamide (DMF), N-methyl-2-pyrrolidone (NMP), dimethylacetamide (DMA), 1,3-dimethyl-2-imidazolidinone (DMI), 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone (DMPU), hexamethylphosphoramide (HMPA); and further dimethyl sulfoxide (DMSO), sulfolane, and water. Mixtures of the above solvents are also possible.

[0063] The reaction may be carried out in the presence of a catalyst, such as an acid or a base, preferably a base. Suitable bases generally include inorganic bases such as LiOH, NaOH, KOH, and Ca(OH)₂; alkali metal and alkaline earth metal oxides such as Li₂O, Na₂O, CaO, and MgO; alkali metal and alkaline earth metal hydrides such as LiH, NaH, KH, and CaH₂; alkali metal and alkaline earth metal carbonates such as Li₂CO₃, K₂CO₃, and CaCO₃; alkali metal bicarbonates such as NaHCO₃; organic bases such as pyrrolidine; tertiary amines such as diisopropylethylamine, trimethylamine, triethylamine, triisopropylamine, and N-methylpiperidine, imidazole, pyridine; substituted pyridines such as collidine, lutidine, and 4-dimethylaminopyridine, and polycyclic amides and amidines such as 1,8-diazabicycloundec-7-ene (DBU), 1,4-diazabicyclo[2.2.2]octane (DABCO); alkali metal salts of secondary amines such as alkyldiisopropylamide, alkali bis(trimethylsilyl)amide, alkali tetramethylpiperidine; alcoholates such as alkali methoxide, alkali ethoxide, alkali isopropanolate, alkali tert-butoxide; alkali metal-alkyl, and alkali metal-aryl salts such as n-butyllithium, tert-butyllithium, phenyllithium. Mixtures of the above-mentioned bases are also possible. The base is generally used in a catalytic amount, but may also be used in an equimolar amount, in an excess amount, or, if appropriate, as a solvent.

[0064] The compound of formula (2) can be prepared as described in WO2017 / 167832A1, for example in Example C-1.

[0065] The compound of formula (1) is commercially available or can be prepared as described in EP3257853A1, for example on page 51, Reaction Scheme 1.

[0066] Therefore, the compound of formula (1a) (wherein all variable elements have the same definitions as in formula (I) and correspond to the definitions of formula (1)) can be prepared, for example, as follows.

[0067]

Chemical formula

[0068] In the first step shown in Process 2, 1-bromobutane-2,3-dione is reacted with the compound of formula (1b) at a high temperature to obtain an imidazole derivative of formula (1c).

[0069]

Chemical formula

[0070] In subsequent process 3, the compound of formula (1c) is then halogenated to obtain the compound of formula (1d)

[0071]

Chemical formula

[0072] Halogenating agents are well known to those skilled in the art. Typical examples include 2-chloro-1,3-bis(methoxycarbonyl)guanidine, N-iodosuccinimide, N-bromosuccinimide, and N-chlorosuccinimide. The reactants are typically applied in equimolar amounts. However, the molar ratio of the halogenating agent to the compound of formula (Ic) may be greater than 1:1, for example, 2.1 or 3:1.

[0073] Thereafter, in Process 4, the compound of formula (Id) is reacted with a thiolate agent R W -S - (which can be applied in the form of its sodium salt Na[R W -S]) to obtain a compound of formula (1e).

[0074]

Chemical formula

[0075] When m > 0, the compound of formula (1e) can be oxidized by the addition of an oxidizing agent as shown in Process 5 to obtain the compound of formula (1f).

[0076]

Chemical formula

[0077] Suitable inert solvents are aliphatic hydrocarbons, preferably aliphatic C5-C 16 -hydrocarbons, more preferably C5-C 16 -alkanes, or C5-C 16 -cycloalkanes, such as pentane, hexane, cyclohexane, or petroleum ether; aromatic hydrocarbons, preferably aromatic C6-C 10 -hydrocarbons, such as benzene, toluene, o-, m-, and p-xylene; halogenated hydrocarbons, preferably halogenated aliphatic C1-C6-alkanes, or halogenated aromatic C6-C 10 -hydrocarbons, such as CH2Cl2, CHCl3, CCl4, CH2ClCH2Cl, CCl3CH3, CHCl2CH2Cl, CCl2CCl2, or chlorobenzene; ethers, preferably C1-C6-cycloalkyl ethers, C1-C6-alkyl-C1-C6-alkyl ethers, and C1-C6-alkyl-C6-C 10 -aryl ethers, such as CH3CH2OCH2CH3, (CH3)2CHOCH(CH3)2, CH3OC(CH3)3 (MTBE), CH3OCH3 (DME), CH3OCH2CH2OCH3, dioxane, anisole, and tetrahydrofuran (THF); esters, preferably esters of aliphatic C1-C6-alcohols and aliphatic C1-C6-carboxylic acids, aromatic C6-C 10 -alcohols and aromatic C6-C 10- esters with carboxylic acids, cyclic esters of ω-hydroxy-C1-C6-carboxylic acids, such as CH3C(O)OCH2CH3, CH3C(O)OCH3, CH3C(O)OCH2CH2CH2CH3, CH3C(O)OCH(CH3)CH2CH3, CH3C(O)OC(CH3), CH3CH2CH2C(O)OCH2CH3, CH3CH(OH)C(O)OCH2CH3, CH3CH(OH)C(O)OCH3, CH3C(O)OCH2CH(CH3)2, CH3C(O)OCH(CH3)2, CH3CH2C(O)OCH3, benzyl benzoate, and γ-butyrolactone; carbonates, such as ethylene carbonate, propylene carbonate, CH3CH2OC(O)OCH2CH3, and CH3OC(O)OCH3; nitriles, preferably C1-C6-nitriles, such as CH3CN and CH3CH2CN; ketones, preferably C1-C6-alkyl-C1-C6-alkyl ketones, such as CH3C(O)CH3, CH3C(O)CH2CH3, CH3CH2C(O)CH2CH3, and CH3C(O)C(CH3)3 (MTBK). Typically, the oxidizing agent is used in an excess, for example, in a ratio greater than 2, such as greater than 3, compared to the compound of formula (1e).

[0078] Then, as shown in Process 6, the compound of formula (1f) or the compound of formula (1e) can be brominated to obtain the compound of formula (1a).

[0079]

Chemical formula

[0080] As another example, a compound of formula (1g) corresponding to the definition of formula (1) can be prepared, for example, as follows.

[0081]

Chemical formula

[0082] In the first step shown in Process 7, dimethyl but-2-ynedioate is reacted with a compound of formula (1h) to obtain an imidazole derivative of formula (1k)

[0083]

Chemical formula

[0084] Suitable solvents are aliphatic hydrocarbons, preferably aliphatic C5-C 16 -hydrocarbons, more preferably C5-C 16 -alkanes, or C5-C 16- Cycloalkanes, such as pentane, hexane, cyclohexane, or petroleum ether; aromatic hydrocarbons, preferably aromatic C6-C 10 - Hydrocarbons, such as benzene, toluene, o-, m-, and p-xylene; halogenated hydrocarbons, preferably halogenated aliphatic C1-C6-alkanes, or halogenated aromatic C6-C 10 - Hydrocarbons, such as CH2Cl2, CHCl3, CCl4, CH2ClCH2Cl, CCl3CH3, CHCl2CH2Cl, CCl2CCl2, or chlorobenzene; ethers, preferably C1-C6-cycloalkyl ethers, C1-C6-alkyl-C1-C6-alkyl ethers and C1-C6-alkyl-C6-C 10 - Aryl ethers, such as CH3CH2OCH2CH3, (CH3)2CHOCH(CH3)2, CH3OC(CH3)3 (MTBE), CH3OCH3 (DME), CH3OCH2CH2OCH3, dioxane, anisole, and tetrahydrofuran (THF); esters, preferably esters of aliphatic C1-C6-alcohols and aliphatic C1-C6-carboxylic acids, aromatic C6-C 10 - Alcohols and aromatic C6-C 10- esters with carboxylic acids, cyclic esters of ω-hydroxy-C1-C6-carboxylic acids, such as CH3C(O)OCH2CH3, CH3C(O)OCH3, CH3C(O)OCH2CH2CH2CH3, CH3C(O)OCH(CH3)CH2CH3, CH3C(O)OC(CH3), CH3CH2CH2C(O)OCH2CH3, CH3CH(OH)C(O)OCH2CH3, CH3CH(OH)C(O)OCH3, CH3C(O)OCH2CH(CH3)2, CH3C(O)OCH(CH3)2, CH3CH2C(O)OCH3, benzyl benzoate, and γ-butyrolactone; carbonates, such as ethylene carbonate, propylene carbonate, CH3CH2OC(O)OCH2CH3, and CH3OC(O)OCH3; nitriles, preferably C1-C6-nitriles, such as CH3CN and CH3CH2CN; ketones, preferably C1-C6-alkyl-C1-C6-alkyl ketones, such as CH3C(O)CH3, CH3C(O)CH2CH3, CH3CH2C(O)CH2CH3, and CH3C(O)C(CH3)3 (MTBK); alcohols, preferably C1-C4-alcohols, such as CH3OH, CH3CH2OH, CH3CH2CH2OH, CH3CH(OH)CH3, CH3(CH2)3OH, and C(CH3)3OH; amides and urea derivatives, preferably dimethylformamide (DMF), N-methyl-2-pyrrolidone (NMP), dimethylacetamide (DMA), 1,3-dimethyl-2-imidazolidinone (DMI), 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone (DMPU), hexamethylphosphoramide (HMPA); and further dimethyl sulfoxide (DMSO), sulfolane, and mixtures thereof. Suitable bases are generally inorganic bases, such as alkali metal and alkaline earth metal hydroxides, such as LiOH, NaOH, KOH, and Ca(OH)2; alkali metal and alkaline earth metal oxides, such as Li2O, Na2O, CaO, and MgO; alkali metal and alkaline earth metal hydrides, such as LiH, NaH, KH, and CaH2; alkali metal and alkaline earth metal carbonates, such as Li2CO3, K2CO3, and CaCO3; and alkali metal bicarbonates, such as NaHCO3.

[0085] The compound of formula (1h) and dimethyl but-2-ynedioate can usually be applied in equimolar amounts, i.e., in a molar ratio of about 1:1. However, in order to optimize the yield, one of the two compounds may be used in excess.

[0086] Then, as shown in Process 8, the compound of formula (1k) can be converted to the compound of formula (1m).

[0087]

Chemical formula

[0088] Next, as described in the same manner as in the above processes 3, 4 and optionally 5 when m > 0, the compound of formula (1m) can be halogenated and reacted with a thiolate agent to obtain the compound of formula (1n).

[0089]

Chemical formula

[0090] Next, the compound of formula (1n) can be converted to the compound of formula (1g) by a series of steps which are standard operations in organic chemistry. First, as shown in process 9, the compound of formula (1n) is saponified under the catalysis of a base to obtain the compound of formula (1o).

[0091]

Chemical formula

[0092] Typical bases that can be used are inorganic bases as described in process 1. Typical solvents are water and aqueous compositions containing water and additional inert solvents. The reaction is typically carried out at a temperature of 0°C to 150°C, preferably 60 to 120°C.

[0093] Thereafter, as shown in Process 10, the carboxylic acid compound of formula (1o) is converted to its corresponding Weinreb amide of formula (1p).

[0094]

Chemical formula

[0095] Then, as shown in Process 11, the Weinreb amide of formula (1p) is reacted with a Grignard reagent to obtain a ketone of formula (1q).

[0096]

Chemical formula

[0097] Finally, the compound of formula 1q in process 12 can be brominated to obtain the compound of formula (1g).

[0098]

Chemical formula

[0099] Q is N(R 5 ) The compound of formula (III) corresponding to the compound of formula (I) can be prepared by reacting the compound of formula (3) with the compound of formula (4) as shown in the following process 13.

[0100]

Chemical formula

[0101] Suitable acids are generally inorganic acids such as HF, HCl, HBr, H2SO4 and HClO4; Lewis acids such as BF3, AlCl3, FeCl3, SnCl4, TiCl4 and ZnCl2, and furthermore organic acids such as HCOOH, CH3COOH, CH3CH2COOH, oxalic acid, toluenesulfonic acid, benzenesulfonic acid, camphorsulfonic acid, citric acid, and CF3COOH.

[0102] Suitable coupling agents are selected from carbodiimides such as DCC (dicyclohexylcarbodiimide) and DIC (diisopropylcarbodiimide), benzotriazole derivatives such as HATU (O-(7-azabenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate), HBTU ((O-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate) and HCTU (1H-benzotriazolium-1-[bis(dimethylamino)methylene]-5-chlorotetrafluoroborate) and phosphonium activating agents such as BOP ((benzotriazol-1-yloxy)-tris(dimethylamino)phosphonium hexafluorophosphate), PyBOP ((benzotriazol-1-yloxy)-tripyrrolidinophosphonium hexafluorophosphate) and PyBrOP (bromotripyrrolidinophosphonium hexafluorophosphate).

[0103] Alternatively, the compound of formula (3) may be substituted with its corresponding carbonyl halide, such as an acid chloride. In this case, the reaction is typically carried out in the presence of a base. Suitable bases are those listed for Process 1 above.

[0104] The compound of formula (3) and the compound of formula (4) are typically reacted with each other in equimolar amounts. It may be advantageous to use an excess of the compound of formula (3) in terms of yield.

[0105] The compound of formula (3) can be prepared as described in EP3257853A1, pages 51 - 53. The compound of formula (4) can be prepared as described in WO2017 / 167832A1, Example C-4, or Bashandy et al. Journal of Enzyme Inhibition and Medicinal Chemistry, 29(5), 619 - 627, 2014.

[0106] Compounds of formulas (1) and (3) other than those described in EP3257853A1 are available by conventional methods of organic chemistry or are commercially available.

[0107] Alternatively, the compound of formula (III) can be prepared by a two-step reaction, including reacting the compound of formula (5) with the compound of formula (2) to obtain the compound of formula (6), as shown in Process 14.

[0108]

Chemical formula

[0109] All variable elements in formulas (2), (5) and (6) have the meanings defined for formula (I). This reaction may be carried out under the same conditions as described for Process 13 above. The compound of formula (5) is commercially available or can be prepared as described in EP3257853A1,

[0247] -

[0266] .

[0110] Then, in the second step, as shown in Process 15, the compound of formula (6) is reacted with the compound of formula (7) to obtain the compound of formula (III) corresponding to the definition of the compound of formula (I).

[0111]

Chemical formula

[0112] All variable elements in formulas (6), (7), and (III) have the meanings defined for formula (I). This type of reaction is described on page 89 of WO2016162318A1. The reaction is typically carried out at a temperature of 15 - 60 °C in an inert solvent in the presence of a base. Suitable solvents are aliphatic hydrocarbons such as pentane, hexane, cyclohexane, or petroleum ether; or aromatic hydrocarbons such as benzene, toluene, o-, m-, and p-xylene. Mixtures of the above solvents are also possible. Suitable bases are generally inorganic bases, preferably alkali metal and alkaline earth metal hydrides such as LiH, NaH, KH, and CaH2; organic bases, preferably secondary amines such as pyrrolidine; or tertiary amines such as diisopropylethylamine, trimethylamine, triethylamine, triisopropylamine, and N-methylpiperidine, imidazole, pyridine; substituted pyridines such as collidine, lutidine, and 4-dimethylaminopyridine, and polycyclic amides and amidines such as 1,8-diazabicycloundec-7-ene (DBU), 1,4-diazabicyclo[2.2.2]octane (DABCO); or alkali metal salts of secondary amines such as alkyldiisopropylamide, alkali bis(trimethylsilyl)amide, alkali tetramethylpiperidine; alcoholates such as alkali methoxide, alkali ethoxide, alkali isopropanolate, alkali tert-butoxide; alkali metal-alkyl, and alkali metal-aryl salts such as n-butyllithium, tert-butyllithium, phenyllithium. Typically, the base is reacted with the compound of formula (7) and then the compound of formula (6) is added to form the thiolate anion.

[0113] The base is generally used in a catalytic amount, but may also be used in an equimolar amount, in excess, or, if appropriate, as a solvent.

[0114] Alternatively, the compound of formula (III) can also be prepared in the Dimroth rearrangement of the compound of formula (8) as shown in Process 16

[0115] [Chemistry] (All variable elements in Formulas (8) and (III) have the meanings defined for Formula (I)). This type of reaction is described in Potts K.T., Surapaneni C.R., 1970, Journal of Heterocyclic Chemistry, or Nagamatsu T., Fujita T., 2002, Heterocycles, 57(4), 631 - 636. The reaction is typically carried out at a temperature of 0 - 80°C, in an inert organic solvent or water, in the presence of a catalyst, usually an acid or a base, such as NaOH or formic acid. If no catalyst is used, the reaction may be carried out at a high temperature, such as 30 - 100°C.)

[0116] The compound of Formula (8) can be prepared by reacting the hydrazine compound of Formula (9) with an orthoester as shown in Process 17.

[0117] [Chemistry] (All variable elements in Formulas (8) and (9) have the meanings defined for Formula (I)). This type of reaction is described by Glushkov V.A. et al., 1998, Pharmaceutical Chemistry Journal, vol.32(5), p.29 - 32 or WO2012148808, page 143. The reaction is typically carried out in an inert organic solvent at a high temperature of 50 - 150°C, in the presence of a Lewis acid, such as FeCl3 or AlCl3. The reaction may be carried out in the presence of an oxidizing agent, such as H2O2 or CuCl2.)

[0118] The compound of Formula (9) can be obtained by reacting the hydrazine compound of Formula (10) with the aldehyde compound of Formula (11) as shown in Process 18.

[0119] [Chemistry] (The variable elements in formulas (9), (10), and (11) have the meanings defined for formula (I)). The reaction is typically carried out in an inert organic solvent in the presence of an acid catalyst, such as toluenesulfonic acid. Suitable solvents are aliphatic hydrocarbons such as pentane, hexane, cyclohexane, or petroleum ether; or aromatic hydrocarbons such as benzene, toluene, o-, m-, and p-xylene. Mixtures of the above solvents are also possible.

[0120] The hydrazine derivatives of formula (10) are commercially available or can be derived from commercially available compounds. Alternatively, the compounds of formula (10) can be prepared by reacting hydrazine with the compounds of formula (12) as shown in Process 19.

[0121]

Chemical formula

[0122] The reaction mixture is worked up in a conventional manner, for example by mixing with water, separating the phases, and, if appropriate, purifying the crude product by chromatography. Some of the intermediates and final products are obtained in the form of colorless or slightly brown viscous oils, which are purified from volatile components under reduced pressure and at a moderately high temperature, or the volatile components are removed. If the intermediates and final products are obtained as solids, purification may also be carried out by recrystallization or digestion.

[0123] The N-oxides can be prepared from the compounds of the invention according to conventional oxidation methods, for example by treating compound 1 with an organic peracid, such as metachloroperbenzoic acid (see WO03 / 64572 or J. Med. Chem. 38(11), 1892-903, 1995); or by treating with an inorganic oxidant, such as hydrogen peroxide (see J. Heterocyc. Chem. 18(7), 1305-8, 1981) or Oxone (see J. Am. Chem. Soc. 123(25), 5962-5973, 2001). The oxidation can result in a pure mono-N-oxide or a mixture of various N-oxides, and the mixture can be separated by conventional methods such as chromatography.

[0124] When the synthesis produces a mixture of isomers, in some cases separation is generally not necessarily required because the individual isomers can interconvert during work-up for use or during application (e.g., under the action of light, acid or base). Such conversions can also occur after use, for example in the treated plant or in the harmful fungi to be controlled, in the treatment of plants.

[0125] It will be readily understood by those skilled in the art that the preferences for the substituents described herein in connection with compound I, and in particular those described in the following table for each substituent, are also applicable mutatis mutandis to the intermediates. Thus, the substituents have the meanings defined herein, in each case independently of one another or, more preferably, in combination.

[0126] Preference The variable elements have the following preferred meanings, each alone and in combination.

[0127] In one embodiment, X is O. In another embodiment of the compound of formula (I), X is S.

[0128] In one embodiment of the compound of formula (I), P is NR 3 and Q is CR6 is. In another embodiment of the compound of formula (I), P is CR 4 is, and Q is NR 5 is.

[0129] In one embodiment of the present invention, the compound of formula (I) is a compound of formula (I.A), a compound of formula (I.B) or a compound of formula (I.C).

[0130]

Chemical formula

[0131] In one embodiment, the compound of formula (I) is a compound of formula (I.A). In another embodiment, the compound of formula (I) is a compound of formula (I.B). In another embodiment, the compound of formula (I) is a compound of formula (I.C).

[0132] R 1 is H, halogen, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C1-C6-alkoxy, C1-C6-alkoxy-C1-C6-alkyl, C3-C6-cycloalkyl, C3-C6-cycloalkoxy, C1-C6-sulfenyl, C1-C6-sulfinyl, or C1-C6-sulfonyl (these groups are unsubstituted or halogenated). In one embodiment, R 1 is H, C1-C3-alkyl, C2-C3-alkenyl, C2-C3-alkynyl, C1-C3-alkoxy, C1-C3-alkoxy-C1-C3-alkyl, C3-C5-cycloalkyl, C3-C5-cycloalkoxy (these groups are unsubstituted or halogenated). In one embodiment, R 1 is H, C1-C3-alkyl, or C1-C3-alkoxy (these groups are unsubstituted or halogenated). In another embodiment, R 1is H, C1-C3-alkyl, C2-C3-alkenyl, C2-C3-alkynyl, C1-C3-alkoxy (these groups being unsubstituted or halogenated). In another embodiment, R 1 is C1-C3-alkyl, C1-C3-alkoxy (these groups being unsubstituted or halogenated). In another embodiment, R 1 is C1-C3-haloalkyl, preferably CF3.

[0133] R 2 , R 4 , R 6 are independently H, halogen, N3, CN, NO2, SCN, SF5; C1-C6-alkyl, C1-C6-alkoxy, C2-C6-alkenyl, tri-C1-C6-alkylsilyl, C2-C6-alkynyl, C1-C6-alkoxy-C1-C4-alkyl, C1-C6-alkoxy-C1-C4-alkoxy, C3-C6-cycloalkyl, C3-C6-cycloalkoxy, C3-C6-cycloalkyl-C1-C4-alkyl, C3-C6-cycloalkoxy-C1-C4-alkyl (these groups being unsubstituted or substituted with halogen); C(=O)OR A , NR B R C , NOR A , ONR B R C , C1-C6-alkylene-NR B R C , O-C1-C6-alkylene-NR B R C , C1-C6-alkylene-CN, NH-C1-C6-alkylene-NR B R C , C(=O)NR B R C , C(=O)R D , C(=S)R D , SO2NR B R C , S(=O) n R E ; phenyl or benzyl (the phenyl ring being unsubstituted or having one or more of the same or different substituents R Fis replaced with).

[0134] In one embodiment, R 2 is H, halogen; C1-C3-alkyl, C1-C3-alkoxy, C2-C3-alkenyl, tri-C1-C6-alkylsilyl, C2-C6-alkynyl, C1-C3-alkoxy-C1-C2-alkyl, C1-C3-alkoxy-C1-C2-alkoxy, C3-C5-cycloalkyl, C3-C5-cycloalkoxy, C3-C5-cycloalkyl-C1-C2-alkyl, C3-C5-cycloalkoxy-C1-C2-alkyl (these groups are unsubstituted or substituted with halogen). In another embodiment, R 2 is H, halogen; C1-C3-alkyl, C1-C3-alkoxy, C2-C3-alkenyl, C2-C6-alkynyl (these groups are unsubstituted or substituted with halogen). In another embodiment, R 2 is H, halogen; C1-C3-alkyl, C1-C3-alkoxy (these groups are unsubstituted or substituted with halogen). In another embodiment, R 2 is H, or C1-C3-alkyl.

[0135] In one embodiment, R 4 is H, halogen; C1-C3-alkyl, C1-C3-alkoxy, C2-C3-alkenyl, tri-C1-C6-alkylsilyl, C2-C6-alkynyl, C1-C3-alkoxy-C1-C2-alkyl, C1-C3-alkoxy-C1-C2-alkoxy, C3-C5-cycloalkyl, C3-C5-cycloalkoxy, C3-C5-cycloalkyl-C1-C2-alkyl, C3-C5-cycloalkoxy-C1-C2-alkyl (these groups are unsubstituted or substituted with halogen). In another embodiment, R 4 is H, halogen; C1-C3-alkyl, C1-C3-alkoxy, C2-C3-alkenyl, C2-C6-alkynyl (these groups are unsubstituted or substituted with halogen). In another embodiment, R 4is H, halogen; C1-C3-alkyl, C1-C3-alkoxy (these groups are unsubstituted or substituted with halogen). In another embodiment, R 4 is H; C1-C3-alkyl, or C1-C3-haloalkyl. In another embodiment, R 4 is H, or C1-C3-alkyl. In another embodiment, R 4 is H.

[0136] In one embodiment, R 6 is H, halogen; C1-C3-alkyl, C1-C3-alkoxy, C2-C3-alkenyl, tri-C1-C6-alkylsilyl, C2-C6-alkynyl, C1-C3-alkoxy-C1-C2-alkyl, C1-C3-alkoxy-C1-C2-alkoxy, C3-C5-cycloalkyl, C3-C5-cycloalkoxy, C3-C5-cycloalkyl-C1-C2-alkyl, C3-C5-cycloalkoxy-C1-C2-alkyl (these groups are unsubstituted or substituted with halogen). In another embodiment, R 6 is H, halogen; C1-C3-alkyl, C1-C3-alkoxy, C2-C3-alkenyl, C2-C6-alkynyl (these groups are unsubstituted or substituted with halogen). In another embodiment, R 6 is H, halogen; C1-C3-alkyl, C1-C3-alkoxy (these groups are unsubstituted or substituted with halogen). In another embodiment, R 6 is H, C1-C3-alkyl, C1-C3-haloalkyl. In another embodiment, R 6 is H, or C1-C3-alkyl.

[0137] R 3 、R 5is, independently, C1-C6-alkyl, C1-C6-alkoxy, C2-C6-alkenyl, C2-C6-alkynyl, C1-C6-alkoxy-C1-C4-alkyl, C1-C6-alkoxy-C1-C4-alkoxy, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C4-alkyl, or C3-C6-cycloalkoxy-C1-C4-alkyl (these are unsubstituted or halogenated); C(=O)OR A , NR B R C , C1-C6-alkylene-NR B R C , O-C1-C6-alkylene-NR B R C , C1-C6-alkylene-CN, NH-C1-C6-alkylene-NR B R C , C(=O)NR B R C , C(=O)R D , C(=S)R D , SO2NR B R C , S(=O) n R E ; phenyl or benzyl (the phenyl ring is unsubstituted or substituted with one or more identical or different substituents R F ).

[0138] In one embodiment, R 3 is C1-C6-alkyl, C1-C6-alkoxy, C2-C6-alkenyl, C2-C6-alkynyl, C1-C6-alkoxy-C1-C4-alkyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C4-alkyl, C3-C6-cycloalkoxy-C1-C4-alkyl, or C1-C3-alkoxy-C1-C3-alkyl (these are unsubstituted or halogenated); phenyl or benzyl (the phenyl ring is unsubstituted or substituted with one or more identical or different substituents R F ). In another embodiment, R 3is C1-C4-alkyl, C2-C4-alkenyl, C2-C4-alkynyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C2-alkyl, or C1-C3-alkoxy-C1-C3-alkyl (these are unsubstituted or halogenated); phenyl or benzyl (the phenyl ring is unsubstituted or substituted with one or more identical or different substituents R F wherein). In another embodiment, R 3 is C1-C4-alkyl, C2-C4-alkenyl, C2-C4-alkynyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C2-alkyl (these are unsubstituted or halogenated); phenyl or benzyl (the phenyl ring is unsubstituted or halogenated). In another embodiment, R 3 is C1-C3-alkyl, C2-C3-alkenyl, C2-C3-alkynyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C2-alkyl (these are unsubstituted or halogenated). In another embodiment, R 3 is C1-C3-alkyl, C2-C3-alkynyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C2-alkyl (these are unsubstituted or halogenated). In another embodiment, R 3 is C1-C3-alkyl, preferably methyl (these are unsubstituted or halogenated).

[0139] In one embodiment, R 5 is C1-C6-alkyl, C1-C6-alkoxy, C2-C6-alkenyl, C2-C6-alkynyl, C1-C6-alkoxy-C1-C4-alkyl, C1-C6-alkoxy-C1-C4-alkoxy, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C4-alkyl, or C3-C6-cycloalkoxy-C1-C4-alkyl (these are unsubstituted or halogenated). In another embodiment, R 5is C1-C3-alkyl, C1-C3-alkoxy, C2-C3-alkenyl, C2-C3-alkynyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C2-alkyl (these are unsubstituted or halogenated). In another embodiment, R 5 is C1-C3-alkyl, C2-C3-alkenyl, C2-C3-alkynyl (these are unsubstituted or halogenated). In another embodiment, R 5 is C1-C3-alkyl, or C1-C3-haloalkyl. In another embodiment, R 5 is C1-C3-alkyl, preferably methyl (these are unsubstituted or halogenated).

[0140] The variable element D is a fused bicyclic ring of the following formula,

[0141]

Chemical formula

[0142] The variable element A is N, S, O, CR 7 , or NR 8 . In one embodiment, A is N, S, or NR 8 . In another embodiment, A is N. In another embodiment, A is S. In another embodiment, A is NR B . In another embodiment, A is O.

[0143] The variable elements E, J are independently C or N, and at least one of the variable elements selected from E and J is C. In one embodiment, E is N and J is C. In another embodiment, E is C and J is N.

[0144] Thus, in one embodiment, E and A are N, and J is C. In another embodiment, J and A are N, and E is C.

[0145] R 7 is H, halogen, OH, CN, NC, NO2, N3, SCN, NCS, NCO, SF5; C1-C6-alkyl, C3-C6-cycloalkyl, C2-C6-alkenyl, C3-C6-cycloalkenyl, C2-C6-alkynyl (these groups are unsubstituted or substituted with one or more identical or different substituents R G ; a 3- to 12-membered saturated, partially unsaturated or fully unsaturated heterocyclic ring or ring system (the heterocyclic ring or ring system contains one or more identical or different heteroatoms O, N, or S, and is unsubstituted or substituted with one or more identical or different substituents R H ; the N and S atoms are independently oxidized or unoxidized); phenyl (which is unsubstituted or substituted with one or more identical or different substituents R J ); OR K , SR K , OC(=O)R K , OC(=O)OR K , OC(=O)NR L R M , OC(=O)SR K , OC(=S)NR L R M , OC(=S)SR K , OS(=O) m R K , OS(=O) m NR L R M , ONR L R M , ON=CR N R O , NR L R M , NOR K , ONR L R M , N=CR N R O , NNR L , N(R L )C(=O)RK , N(R L )C(=O)OR K , S(=O) n R V , SC(=O)SR K , SC(=O)NR L R M , S(=O) m NR L R M , C(=O)R P , C(=S)R P , C(=O)NR L R M , C(=O)OR K , C(=S)NR L R M , C(=S)OR K , C(=S)SR K , C(=NR L )R M , C(=NR L )NR M R R , or Si(R S )2R T .

[0146] In one embodiment, R 7 is H, halogen, OH, CN, NC, NO2, N3, SF5; C1-C3-alkyl, C1-C3-alkoxy, C3-C6-cycloalkyl, C2-C3-alkenyl, C3-C6-cycloalkenyl, C2-C3-alkynyl (these groups are unsubstituted or halogenated). In another embodiment, R 7 is H, halogen; C1-C3-alkyl, C1-C3-alkoxy (these groups are unsubstituted or halogenated).

[0147] R 8 is H, halogen, CN; C1-C6-alkyl, C3-C6-cycloalkyl, C2-C6-alkenyl, C3-C6-cycloalkenyl, C2-C6-alkynyl (these groups are unsubstituted or substituted with one or more of the same or different substituents R G ); A saturated, partially unsaturated or fully unsaturated heterocyclic ring or ring system having 3 to 12 members (said heterocyclic ring or ring system contains one or more identical or different heteroatoms O, N or S, and is unsubstituted or substituted with one or more identical or different substituents R H and the N and S atoms are independently oxidized or unoxidized); phenyl (which is unsubstituted or substituted with one or more identical or different substituents R J ); OR K SR K OC(=O)R K OC(=O)OR K OC(=O)NR L R M OC(=O)SR K OC(=S)NR L R M OC(=S)SR K OS(=O) m R K OS(=O) m NR L R M ONR L R M ON=CR N R O NR L R M NOR K ONR L R M N=CR N R O NNR L N(R L )C(=O)R K N(R L )C(=O)OR K S(=O) n R V SC(=O)SR K SC(=O)NR L R M S(=O) m NR L R M C(=O)R P C(=S)R P C(=O)NR L R M C(=O)OR K, C(=S)NR L R M , C(=S)OR K , C(=S)SR K , C(=NR L )R M , C(=NR L )NR M R R , or Si(R S )2R T is.

[0148] In one embodiment, R 8 is H, halogen, OH, CN, NC, NO2, N3, SF5; C1-C3-alkyl, C1-C3-alkoxy, C3-C6-cycloalkyl, C2-C3-alkenyl, C3-C6-cycloalkenyl, C2-C3-alkynyl (these groups are unsubstituted or halogenated). In another embodiment, R 8 is H, halogen; C1-C3-alkyl, C1-C3-alkoxy (these groups are unsubstituted or halogenated).

[0149] Each R 9 is independently H, halogen, OH, CN, NC, NO2, N3, SCN, NCS, NCO, SF5; C1-C6-alkyl, C3-C6-cycloalkyl, C2-C6-alkenyl, C3-C6-cycloalkenyl, C2-C6-alkynyl, C3-C6-cycloalkyl-C1-C3-alkyl (these groups are unsubstituted or substituted with one or more of the same or different substituents R G ); a 3- to 12-membered saturated, partially unsaturated or fully unsaturated heterocyclic ring or ring system (the heterocyclic ring or ring system contains one or more of the same or different heteroatoms O, N, or S, is unsubstituted or substituted with one or more of the same or different substituents R H and the N and S atoms are independently oxidized or unoxidized); phenyl (which is unsubstituted or substituted with one or more of the same or different substituents R J ); OR K , SR K , OC(=O)R K, OC(=O)OR K , OC(=O)NR L R M , OC(=O)SR K , OC(=S)NR L R M , OC(=S)SR K , OS(=O) m R K , OS(=O) m NR L R M , ONR L R M , ON=CR N R O , NR L R M , NOR K , ONR L R M , N=CR N R O , NNR L , N(R L )C(=O)R K , N(R L )C(=O)OR K , S(=O) n R V , SC(=O)SR K , SC(=O)NR L R M , S(=O) m NR L R M , C(=O)R P , C(=S)R P , C(=O)NR L R M , C(=O)OR K , C(=S)NR L R M , C(=S)OR K , C(=S)SR K , C(=NR L )R M , C(=NR L )NR M R R , Si(R S )2R T or; alternatively, two substituents R 9together with the ring members of the ring G to which they are attached to form a 5- or 6-membered saturated, partially unsaturated or fully unsaturated carbocyclic or heterocyclic ring, which carbocyclic or heterocyclic ring is unsubstituted or has one or more of the same or different substituents R J and is substituted, and the heterocyclic ring contains one or more of the same or different heteroatoms O, N or S.

[0150] In one embodiment, each R 9 is independently H, halogen, OH, CN, NO2, SF5; C1-C3-alkyl, C3-C6-cycloalkyl, C2-C3-alkenyl, C3-C6-cycloalkenyl, C2-C3-alkynyl, C3-C6-cycloalkyl-C1-C2-alkyl (these groups being unsubstituted or having one or more of the same or different substituents R G substituting); a 5- to 6-membered saturated, partially unsaturated or fully unsaturated heterocyclic ring or ring system (said heterocyclic ring or ring system containing one or more of the same or different heteroatoms O, N, or S and being unsubstituted or having one or more of the same or different substituents R H substituting, and said N and S atoms being independently oxidized or unoxidized); phenyl (which is unsubstituted or has one or more of the same or different substituents R J substituting); OR K , SR K , OC(=O)R K , OC(=O)OR K , OC(=O)NR L R M , ONR L R M , ON=CR N R O , NR L R M , NOR K , ONR L R M , N=CR N R O , NNR L , N(R L )C(=O)R K , N(R L )C(=O)OR K , S(=O) nR V 、 C(=O)R P 、 C(=O)NR L R M 、 C(=O)OR K or; alternatively, two substituents R 9 together with the ring members of the ring G to which they are attached form a 5- or 6-membered saturated, partially unsaturated or fully unsaturated carbocyclic or heterocyclic ring, which carbocyclic or heterocyclic ring is unsubstituted or substituted with one or more identical or different substituents R J and the heterocyclic ring contains one or more identical or different heteroatoms O, N or S.

[0151] In another embodiment, each R 9 is independently H, halogen, OH, CN; C1-C3-alkyl, C3-C6-cycloalkyl, C2-C3-alkenyl, C3-C6-cycloalkenyl, C2-C3-alkynyl, C3-C6-cycloalkyl-C1-C2-alkyl (these groups being unsubstituted or substituted with one or more identical or different substituents R G ); phenyl (which is unsubstituted or substituted with one or more identical or different substituents R J ); OR K 、 SR K 、 OC(=O)R K 、 OC(=O)OR K 、 OC(=O)NR L R M 、 ONR L R M 、 ON=CR N R O 、 NR L R M 、 NOR K 、 ONR L R M 、 N=CR N R O 、 NNR L 、 N(R L )C(=O)R K 、 N(R L )C(=O)OR K 、 S(=O) n R V 、 C(=O)R P 、 C(=O)NRL R M 、 or C(=O)OR K is.

[0152] In another embodiment, each R 9 is independently H, halogen, OH, CN; C1-C3-alkyl, C1-C3-alkoxy, C2-C3-alkenyl, or C2-C3-alkynyl (these groups are unsubstituted or halogenated).

[0153] In another embodiment, each R 9 is independently H, halogen, OH, CN; C1-C3-alkyl, C1-C3-alkoxy, C2-C3-alkenyl, or C2-C3-alkynyl (these groups are unsubstituted or halogenated), and at least one substituent R 9 is C1-C3-alkyl, or C3-C6-cycloalkyl (these groups are substituted with CN), such as 1-cyano-cyclopropyl and 1-cyanoisopropyl. In another embodiment, R 9 is H, C1-C3-alkyl, or C1-C3-haloalkyl.

[0154] In another embodiment, each R 9 is independently H, halogen, OH, CN; C1-C3-alkyl, C1-C3-alkoxy, C2-C3-alkenyl, or C2-C3-alkynyl (these groups are unsubstituted or halogenated), and at least one substituent R 9 is -C(CN)R 91 R 92 ; or C3-C6-cycloalkyl (which is substituted with CN and has no further substituents or is further substituted with one or more of the same or different substituents R 93 ).

[0155] In another embodiment, at least one R 9 is -C(CN)R 91 R 92; or C3-C6-cycloalkyl which is substituted with CN and has no further substituents or is further substituted with one or more identical or different substituents R 93 ).

[0156] R 91 and each R 92 is independently halogen, CN, C1-C6-alkyl, C1-C6-haloalkyl, C3-C6-cycloalkyl, C1-C3-alkoxy, C1-C4-alkoxy-C1-C4-alkyl, C1-C4-alkylsulfanyl, or C1-C4-alkoxycarbonyl. In one embodiment, each of R 91 and R 92 is independently halogen, CN, C1-C6-alkyl, or C1-C6-haloalkyl. Typically, neither R 91 nor R 92 is H. Preferably, R 91 and R 92 are independently selected from C1-C6-alkyl, C1-C6-haloalkyl, C3-C6-cycloalkyl, C1-C4-alkoxy, and C1-C4-alkoxy-C1-C4-alkyl, most preferably from C1-C6-alkyl, C1-C6-haloalkyl, C3-C6-cycloalkyl, and C1-C4-alkoxy, particularly preferably from C1-C6-alkyl and C1-C6-haloalkyl, especially from C1-C3-alkyl and C1-C3-haloalkyl, for example from C1-C3-alkyl. In a particularly preferred embodiment, both R 91 and R 92 are CH3.

[0157] Each R 93is, independently, halogen, CN, C(=O)H, OH, C3-C6-cycloalkyl, C(=O)OH, C(=O)NH2, C1-C4-haloalkoxy, C1-C4-alkoxy, C1-C4-haloalkylsulfanyl, C1-C4-haloalkylsulfinyl, C1-C4-haloalkylsulfonyl, C1-C4-alkoxycarbonyl, C1-C4-haloalkoxycarbonyl, C1-C4-alkylcarbonyl, C1-C4-haloalkylcarbonyl, di-(C1-C4)alkylaminocarbonyl, C1-C4-alkylaminocarbonyl, C1-C4-alkylcarbonylamino, di-(C1-C4)alkylcarbonylamino, C1-C4-alkoxycarbonylamino, C1-C4-alkyl (which is unsubstituted or halogenated). In one embodiment, R 93 is halogen, CN, C1-C3-alkyl, or C1-C3-cyanoalkyl.

[0158] In another embodiment, two substituents R 9 together with the ring members of the ring G to which they are attached form a 5- or 6-membered saturated, partially unsaturated or fully unsaturated carbocyclic or heterocyclic ring, which carbocyclic or heterocyclic ring is unsubstituted or substituted with one or more of the same or different substituents R J and the heterocyclic ring contains one or more of the same or different heteroatoms O, N or S.

[0159] Each R A is, independently, H; C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C1-C6-alkoxy-C1-C4-alkyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C4-alkyl, C3-C6-cycloalkoxy-C1-C4-alkyl (these groups are unsubstituted or substituted with halogen); C1-C6-alkylene-NR b R c , C1-C6-alkylene-CN; or phenyl or benzyl (the phenyl ring is unsubstituted or substituted with one or more of the same or different substituents R F ).

[0160] In one embodiment, each R A is independently H; C1-C3-alkyl, C2-C3-alkenyl, C2-C3-alkynyl, C1-C3-alkoxy-C1-C2-alkyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C2-alkyl, C3-C6-cycloalkoxy-C1-C2-alkyl (these groups are unsubstituted or substituted with halogen); or phenyl or benzyl (the phenyl ring is unsubstituted or substituted with one or more identical or different substituents R F .

[0161] In one embodiment, each R A is independently H; C1-C3-alkyl, C2-C3-alkenyl, C2-C3-alkynyl, C3-C6-cycloalkyl (these groups are unsubstituted or substituted with halogen); or phenyl or benzyl (the phenyl ring is unsubstituted or substituted with one or more identical or different substituents selected from halogen, C1-C3-alkyl, C1-C3-alkoxy, C1-C3-haloalkoxy, and C1-C3-haloalkyl).

[0162] Each R B is independently H; C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C1-C6-alkoxy-C1-C4-alkyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C4-alkyl, C3-C6-cycloalkoxy-C1-C4-alkyl (these groups are unsubstituted or substituted with halogen); C1-C6-alkylene-CN; phenyl and benzyl (these groups are unsubstituted or substituted with one or more identical or different substituents R F .

[0163] In one embodiment, each R Bis, independently, H; C1-C3-alkyl, C2-C3-alkenyl, C2-C3-alkynyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C4-alkyl (these groups are unsubstituted or substituted with halogen); phenyl or benzyl (these groups are unsubstituted or substituted with one or more identical or different substituents R F and is substituted).

[0164] In another embodiment, each R B is, independently, H; C1-C3-alkyl, C2-C3-alkenyl, C2-C3-alkynyl, C3-C6-cycloalkyl (these groups are unsubstituted or substituted with halogen); phenyl or benzyl (these groups are unsubstituted or substituted with one or more identical or different substituents selected from halogen, C1-C3-alkyl, C1-C3-alkoxy, C1-C3-haloalkoxy, and C1-C3-haloalkyl).

[0165] Each R C is, independently, H; C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C1-C6-alkoxy-C1-C4-alkyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C4-alkyl, C3-C6-cycloalkoxy-C1-C4-alkyl (these groups are unsubstituted or substituted with halogen); C1-C6-alkylene-CN; or phenyl or benzyl (the phenyl ring is unsubstituted or substituted with one or more identical or different substituents R F and is substituted).

[0166] In one embodiment, each R C is, independently, H; C1-C3-alkyl, C2-C3-alkenyl, C2-C3-alkynyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C4-alkyl (these groups are unsubstituted or substituted with halogen); phenyl or benzyl (these groups are unsubstituted or substituted with one or more identical or different substituents R Fis replaced by).

[0167] In another embodiment, each R C is independently H; C1-C3-alkyl, C2-C3-alkenyl, C2-C3-alkynyl, C3-C6-cycloalkyl (these groups are unsubstituted or substituted with halogen); phenyl or benzyl (these groups are unsubstituted or substituted with one or more same or different substituents selected from halogen, C1-C3-alkyl, C1-C3-alkoxy, C1-C3-haloalkoxy, and C1-C3-haloalkyl).

[0168] Alternatively, each moiety NR B R C may also form a saturated 5- to 8-membered heterocyclic ring bonded to N, which heterocyclic ring may have one or two additional heteroatoms or heteroatom moieties selected from O, S(=O) m and N-R', where R' is H or C1-C6-alkyl, and the heterocyclic ring bonded to N is unsubstituted or substituted with one or more same or different substituents selected from halogen, C1-C4-alkyl, C1-C4-haloalkyl, C1-C4-alkoxy and C1-C4-haloalkoxy. In one embodiment, each moiety NR B R C may also form a saturated 5- to 6-membered heterocyclic ring bonded to N, and the heterocyclic ring bonded to N is unsubstituted or substituted with one or more same or different substituents selected from halogen, C1-C3-alkyl, C1-C3-haloalkyl, C1-C3-alkoxy and C1-C3-haloalkoxy.

[0169] Each R Dis, independently, H; C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C1-C6-alkoxy-C1-C4-alkyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C4-alkyl, C3-C6-cycloalkoxy-C1-C4-alkyl (these groups are unsubstituted or substituted with halogen); phenyl or benzyl (the phenyl ring is unsubstituted or substituted with one or more identical or different substituents R F and is substituted).

[0170] In one embodiment, each R D is, independently, C1-C3-alkyl, C2-C3-alkenyl, C2-C3-alkynyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C4-alkyl (these groups are unsubstituted or substituted with halogen); phenyl or benzyl (these groups are unsubstituted or substituted with one or more identical or different substituents R F and is substituted). In another embodiment, each R D is, independently, C1-C3-alkyl, C2-C3-alkenyl, C2-C3-alkynyl, C3-C6-cycloalkyl (these groups are unsubstituted or substituted with halogen); phenyl or benzyl (these groups are unsubstituted or substituted with one or more identical or different substituents selected from halogen, C1-C3-alkyl, C1-C3-alkoxy, C1-C3-haloalkoxy, and C1-C3-haloalkyl).

[0171] Each R E is, independently, C1-C6-alkyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C4-alkyl (these are unsubstituted or substituted with halogen); or phenyl or benzyl (the phenyl ring is unsubstituted or substituted with R F and is substituted).

[0172] In one embodiment, each R Eis, independently, C1-C3-alkyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C2-alkyl (these are unsubstituted or substituted with halogen); or phenyl or benzyl (the phenyl ring is unsubstituted or substituted with one or more same or different substituents selected from halogen, C1-C3-alkyl, C1-C3-alkoxy, C1-C3-haloalkoxy, and C1-C3-haloalkyl). In one embodiment, each R E is, independently, C1-C3-alkyl, or C1-C3-haloalkyl.

[0173] Each R F is, independently, halogen, N3, OH, CN, NO2, SCN, SF5; C1-C6 alkyl, C1-C6 alkoxy, C2-C6 alkenyl, C2-C6 alkynyl, C1-C6 alkoxy-C1-C4 alkyl, C1-C6 alkoxy-C1-C4 alkoxy, C3-C6 cycloalkyl, C3-C6 cycloalkoxy, C3-C6 cycloalkyl-C1-C4 alkyl, C3-C6 cycloalkoxy-C1-C4 alkyl (these groups are unsubstituted or substituted with halogen). In one embodiment, each R F is, independently, halogen, OH, CN, NO2; C1-C3-alkyl, C1-C3-alkoxy, C2-C3 alkenyl, C2-C3-alkynyl, C3-C6-cycloalkyl (these groups are unsubstituted or substituted with halogen). In another embodiment, each R F is, independently, halogen; C1-C3-alkyl, C1-C3-alkoxy, C2-C3-alkenyl, C2-C3-alkynyl (these groups are unsubstituted or substituted with halogen). In another embodiment, each R F is, independently, halogen, C1-C3-alkyl, or C1-C3-haloalkyl.

[0174] Each R Gis, independently, halogen, OH, CN, NC, NO2; C1-C6-alkyl, C3-C6-cycloalkyl, C3-C6-cycloalkenyl (these groups are unsubstituted or substituted with one or more same or different substituents selected from halogen, OH, CN, C1-C3-alkoxy, C1-C3-haloalkoxy, and C1-C3-alkyl-carbonyl); a 3- to 12-membered saturated, partially unsaturated or fully unsaturated heterocyclic ring or ring system (the heterocyclic ring or ring system contains one or more same or different heteroatoms O, N or S, is unsubstituted or substituted with one or more same or different substituents selected from halogen, OH, CN, C1-C3-alkoxy, C1-C3-haloalkoxy, and C1-C3-alkyl-carbonyl, and the N and S atoms are independently oxidized or not oxidized); phenyl (which is unsubstituted or substituted with one or more same or different substituents selected from halogen, OH, CN, NO2, C1-C3-alkyl, C1-C3-haloalkyl, C1-C3-alkoxy, C1-C3-haloalkoxy, and C1-C3-alkyl-carbonyl); OR K , SR K , OC(=O)R K , OC(=O)OR K , OC(=O)NR L R M , OC(=O)SR K , OC(=S)NR L R M , OC(=S)SR K , OS(=O) m R K , OS(=O) m NR L R M , ONR L R M , ON=CR N R O , NR L R M , NOR K , ONR L R M , N=CR N R O , NNR L , N(R L )C(=O)RK , N(R L )C(=O)OR K , S(=O) n R V , SC(=O)SR K , SC(=O)NR L R M , S(=O) m , NR L R M , C(=O)R P , C(=S)R P , C(=O)NR L R M , C(=O)OR K , C(=S)NR L R M , C(=S)OR K , C(=S)SR K , C(=NR L )R M , C(=NR L )NR M R R , Si(R S )2R T is.

[0175] In one embodiment, each R Gis, independently, halogen, OH, CN; C1-C3-alkyl, C3-C6-cycloalkyl, C3-C6-cycloalkenyl (these groups being unsubstituted or substituted by one or more identical or different substituents selected from halogen, OH, CN, C1-C3-alkoxy, C1-C3-haloalkoxy, and C1-C3-alkyl-carbonyl); a 5- to 6-membered saturated, partially unsaturated or fully unsaturated heterocyclic ring or ring system (said heterocyclic ring or ring system containing one or more identical or different heteroatoms O, N or S, being unsubstituted or substituted by one or more identical or different substituents selected from halogen, OH, CN, C1-C3-alkoxy, C1-C3-haloalkoxy, and C1-C3-alkyl-carbonyl, the N and S atoms being independently oxidized or unoxidized); phenyl (which is unsubstituted or substituted by one or more identical or different substituents selected from halogen, OH, CN, NO2, C1-C3-alkyl, C1-C3-haloalkyl, C1-C3-alkoxy, C1-C3-haloalkoxy, and C1-C3-alkyl-carbonyl); OR K , SR K , OC(=O)R K , OC(=O)OR K , OC(=O)NR L R M , ONR L R M , ON=CR N R O , NR L R M , NOR K , ONR L R M , NNR L , N(R L )C(=O)R K , N(R L )C(=O)OR K , C(=O)R P , C(=S)R P , C(=O)NR L R M , C(=O)OR K is. In one embodiment, each R Gis independently halogen, CN; C1-C3-alkyl, C1-C3-alkoxy, C1-C3-haloalkyl, C1-C3-haloalkoxy, or phenyl. In another embodiment, each R G is independently halogen, C1-C3-alkyl, C1-C3-alkoxy, C1-C3-haloalkyl, or C1-C3-haloalkoxy. In another embodiment, each R G is independently halogen.

[0176] Each R H is independently halogen, CN, NC, NO2, SCN, NCS, NCO; C1-C6-alkyl, C3-C6-cycloalkyl, C3-C6-cycloalkenyl (these groups are unsubstituted or substituted with one or more identical or different substituents selected from halogen, OH, CN, C1-C 10 -alkoxy, C1-C3-haloalkoxy, and C1-C3-alkyl-carbonyl); phenyl (which is unsubstituted or substituted with halogen, OH, CN, NO2, C1-C3-alkyl, C1-C3-haloalkyl, OR K 、SR K 、OC(=O)R K 、OC(=O)OR K 、OC(=O)NR L R M 、OC(=O)SR K 、OC(=S)NR L R M 、OC(=S)SR K 、OS(=O) m R K 、OS(=O) m NR L R M 、ONR L R M 、ON=CR N R O 、NR L R M 、NOR K 、ONR L R M 、N=CR N R O 、NNR L 、N(RL )C(=O)R K 、N(R L )C(=O)OR K 、S(=O) n R V 、SC(=O)SR K 、SC(=O)NR L R M 、S(=O) m NR L R M 、C(=O)R P 、C(=S)R P 、C(=O)NR L R M 、C(=O)OR K 、C(=S)NR L R M 、C(=S)OR K 、C(=S)SR K 、C(=NR L )R M 、C(=NR L )NR M R R 、Si(R S )2R T is substituted with one or more identical or different substituents selected from); or two geminal substituents R H together with the atom to which they are attached form a =O, =S, or =NR L group. In one embodiment, each R H is independently halogen, CN; C1-C3-alkyl, C1-C3-haloalkyl, C1-C3-alkoxy, or C1-C3-haloalkoxy.

[0177] Each R J is independently halogen, CN, NC, NO2, SCN, NCS, NCO; C1-C6-alkyl, C3-C6-cycloalkyl, C3-C6-cycloalkenyl (these groups are unsubstituted or halogen, OH, CN, C1-C 10-alkoxy, C1-C3-haloalkoxy, and one or more identical or different substituents selected from C1-C3-alkyl-carbonyl); phenyl (which is unsubstituted or halogen, OH, CN, NO2, C1-C3-alkyl, C1-C3-haloalkyl, OR K 、SR K 、OC(=O)R K 、OC(=O)OR K 、OC(=O)NR L R M 、OC(=O)SR K 、OC(=S)NR L R M 、OC(=S)SR K 、OS(=O) m R K 、OS(=O) m NR L R M 、ONR L R M 、ON=CR N R O 、NR L R M 、NOR K 、ONR L R M 、N=CR N R O 、NNR L 、N(R L )C(=O)R K 、N(R L )C(=O)OR K 、S(=O) n R V 、SC(=O)SR K 、SC(=O)NR L R M 、S(=O) m NR L R M 、C(=O)R P 、C(=S)R P 、C(=O)NR L R M 、C(=O)OR K 、C(=S)NR L R M 、C(=S)OR K 、C(=S)SR K 、C(=NR L)R M 、C(=NR L )NR M R R 、 or Si(R S )2R T and is substituted with one or more identical or different substituents selected therefrom). In one embodiment, each R J is independently halogen, CN; C1-C3-alkyl, C1-C3-haloalkyl, C1-C3-alkoxy, or C1-C3-haloalkoxy.

[0178] Each R K is independently H; C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C1-C6-alkoxy-C1-C4-alkyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C4-alkyl, C3-C6-cycloalkoxy-C1-C4-alkyl (these groups are unsubstituted or substituted with halogen, CN, NR M R N ; C(=O)NR M R N , C(=O)R T and is substituted with one or more identical or different substituents selected therefrom); or phenyl or benzyl (the phenyl ring is unsubstituted or substituted with one or more identical or different substituents R X ).

[0179] In one embodiment, each R K is independently C1-C3-alkyl, C2-C3-alkenyl, C2-C3-alkynyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C4-alkyl (these groups are unsubstituted or substituted with halogen); phenyl or benzyl (these groups are unsubstituted or substituted with one or more identical or different substituents R X ). In another embodiment, each R Kis independently C1-C3-alkyl, C2-C3-alkenyl, C2-C3-alkynyl, C3-C6-cycloalkyl (these groups being unsubstituted or substituted by halogen); phenyl or benzyl (these groups being unsubstituted or substituted by one or more identical or different substituents selected from halogen, C1-C3-alkyl, C1-C3-alkoxy, C1-C3-haloalkoxy, and C1-C3-haloalkyl).

[0180] Each R L is independently H; C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C1-C6-alkoxy-C1-C4-alkyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C4-alkyl, C3-C6-cycloalkoxy-C1-C4-alkyl (these groups being unsubstituted or substituted by halogen); C1-C6-alkylene-CN; phenyl and benzyl (these groups being unsubstituted or substituted by one or more identical or different substituents R X ).

[0181] In one embodiment, each R L is independently H; C1-C3-alkyl, C2-C3-alkenyl, C2-C3-alkynyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C4-alkyl (these groups being unsubstituted or substituted by halogen); phenyl or benzyl (these groups being unsubstituted or substituted by one or more identical or different substituents R X ). In another embodiment, each R L is independently H; C1-C3-alkyl, C2-C3-alkenyl, C2-C3-alkynyl, C3-C6-cycloalkyl (these groups being unsubstituted or substituted by halogen); phenyl or benzyl (these groups being unsubstituted or substituted by one or more identical or different substituents selected from halogen, C1-C3-alkyl, C1-C3-alkoxy, C1-C3-haloalkoxy, and C1-C3-haloalkyl).

[0182] each R M and R R are each, independently, H; C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C1-C6-alkoxy-C1-C4-alkyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C4-alkyl, C3-C6-cycloalkoxy-C1-C4-alkyl (these groups being unsubstituted or substituted by halogen); C1-C6-alkylene-CN; or phenyl or benzyl (the phenyl ring being unsubstituted or substituted by one or more identical or different substituents R X ).

[0183] In one embodiment, each R M and R R are each, independently, H; C1-C3-alkyl, C2-C3-alkenyl, C2-C3-alkynyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C4-alkyl (these groups being unsubstituted or substituted by halogen); phenyl or benzyl (these groups being unsubstituted or substituted by one or more identical or different substituents R X ). In another embodiment, each R M and R R are each, independently, H; C1-C3-alkyl, C2-C3-alkenyl, C2-C3-alkynyl, C3-C6-cycloalkyl (these groups being unsubstituted or substituted by halogen); phenyl or benzyl (these groups being unsubstituted or substituted by one or more identical or different substituents selected from halogen, C1-C3-alkyl, C1-C3-alkoxy, C1-C3-haloalkoxy, and C1-C3-haloalkyl).

[0184] Alternatively, each moiety NR M R R or NR L R M may also form a saturated 5- to 8-membered heterocycle attached to N, which heterocycle, in addition to the nitrogen atom, contains O, S(=O) mand may have one or two further heteroatoms or heteroatom moieties selected from N-R', where R' is H or C1-C6-alkyl, and the heterocyclic ring attached to N is unsubstituted or substituted with one or more identical or different substituents selected from halogen, C1-C4-alkyl, C1-C4-haloalkyl, C1-C4-alkoxy and C1-C4-haloalkoxy. In one embodiment, each moiety NR M R R , or NR L R M may also form a saturated 5- to 6-membered heterocyclic ring attached to N, and the heterocyclic ring attached to N is unsubstituted or substituted with one or more identical or different substituents selected from halogen, C1-C3-alkyl, C1-C3-haloalkyl, C1-C3-alkoxy and C1-C3-haloalkoxy.

[0185] Each R N is independently H, halogen, CN, NO2, SCN; C1-C 10 -alkyl, C3-C8-cycloalkyl, C2-C 10 -alkenyl, C3-C8-cycloalkenyl, C2-C 10 -alkynyl (these groups being unsubstituted or substituted with one or more identical or different substituents selected from halogen, C1-C6-alkyl, C1-C6-alkoxy, C1-C6-haloalkyl, and C1-C6-haloalkoxy); a 3- to 12-membered saturated, partially unsaturated or fully unsaturated heterocyclic ring or ring system (said heterocyclic ring or ring system containing one or more identical or different heteroatoms O, N or S, unsubstituted or substituted with one or more identical or different substituents selected from halogen, C1-C3-alkyl, C1-C3-alkoxy, C1-C3-haloalkyl, and C1-C3-haloalkoxy, said N and S atoms being independently oxidized or unoxidized); phenyl (which is unsubstituted or substituted with one or more identical or different substituents selected from halogen, C1-C3-alkyl, C1-C3-alkoxy, C1-C3-haloalkyl, and C1-C3-haloalkoxy).

[0186] In one embodiment, each R N is independently C1-C3-alkyl, C2-C3-alkenyl, C2-C3-alkynyl, C3-C6-cycloalkyl (these groups being unsubstituted or substituted with halogen); phenyl (which is unsubstituted or substituted with one or more identical or different substituents selected from halogen, C1-C3-alkyl, C1-C3-alkoxy, C1-C3-haloalkyl, and C1-C3-haloalkoxy). In another embodiment, each R N is independently C1-C3-alkyl, C2-C3-alkenyl, C2-C3-alkynyl, C3-C6-cycloalkyl (these groups being unsubstituted or substituted with halogen); phenyl (which is unsubstituted or substituted with one or more identical or different substituents selected from halogen, C1-C3-alkyl, C1-C3-alkoxy, C1-C3-haloalkyl, and C1-C3-haloalkoxy).

[0187] Each R O is independently H, C1-C4-alkyl, C1-C6-cycloalkyl, C1-C2-alkoxy-C1-C2-alkyl, phenyl, or benzyl.

[0188] In one embodiment, each R O is independently H, or C1-C3-alkyl.

[0189] Each R P is independently H; C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C1-C6-alkoxy-C1-C4-alkyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C4-alkyl, C3-C6-cycloalkoxy-C1-C4-alkyl (these groups being unsubstituted or substituted with halogen); phenyl or benzyl (the phenyl ring being unsubstituted or substituted with one or more identical or different substituents R X ).

[0190] In one embodiment, each R P is independently C1-C3-alkyl, C2-C3-alkenyl, C2-C3-alkynyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C4-alkyl (these groups are unsubstituted or substituted with halogen); phenyl or benzyl (these groups are unsubstituted or substituted with one or more of the same or different substituents R X ). In another embodiment, each R P is independently C1-C3-alkyl, C2-C3-alkenyl, C2-C3-alkynyl, C3-C6-cycloalkyl (these groups are unsubstituted or substituted with halogen); phenyl or benzyl (these groups are unsubstituted or substituted with one or more of the same or different substituents selected from halogen, C1-C3-alkyl, C1-C3-alkoxy, C1-C3-haloalkoxy, and C1-C3-haloalkyl).

[0191] Each R S , R T is independently H, C1-C 10 -alkyl, C1-C6-haloalkyl, C1-C 10 -alkoxy, C1-C4-alkoxy-C1-C4-alkyl, C3-C8-cycloalkyl, C3-C8-halocycloalkyl, C1-C4-haloalkoxy-C1-C4-alkyl, or phenyl. In one embodiment, each R S , R T is independently H, C1-C3-alkyl, or C1-C3-haloalkyl.

[0192] Each R V is independently C1-C6-alkyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C4-alkyl (these are unsubstituted or substituted with halogen); or phenyl or benzyl (the phenyl ring is unsubstituted or substituted with R X ). In one embodiment, each R Vis independently C1-C3-alkyl, C1-C3-haloalkyl; or phenyl or benzyl (the phenyl ring is unsubstituted or halogenated).

[0193] R W is independently C1-C6-alkyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C4-alkyl (these are unsubstituted or substituted with halogen); or phenyl or benzyl (the phenyl ring is unsubstituted or substituted with one or more of the same or different substituents R X . In one embodiment, each R W is independently C1-C3-alkyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C2-alkyl (these are unsubstituted or substituted with halogen); or phenyl or benzyl (the phenyl ring is unsubstituted or substituted with one or more of the same or different substituents selected from halogen, C1-C3-alkyl, C1-C3-alkoxy, C1-C3-haloalkoxy, and C1-C3-haloalkyl). In one embodiment, each R W is independently C1-C3-alkyl, or C1-C3-haloalkyl.

[0194] Each R X is independently halogen, N3, OH, CN, NO2, SCN, SF5; C1-C6 alkyl, C1-C6 alkoxy, C2-C6 alkenyl, C2-C6 alkynyl, C1-C6 alkoxy-C1-C4 alkyl, C1-C6 alkoxy-C1-C4 alkoxy, C3-C6 cycloalkyl, C3-C6 cycloalkoxy, C3-C6 cycloalkyl-C1-C4 alkyl, C3-C6 cycloalkoxy-C1-C4 alkyl (these groups are unsubstituted or substituted with halogen). In one embodiment, each R Xis, independently, halogen, OH, CN, NO2; C1-C3-alkyl, C1-C3-alkoxy, C2-C3 alkenyl, C2-C3-alkynyl, C3-C6-cycloalkyl (these groups are unsubstituted or substituted with halogen). In another embodiment, each R X is, independently, halogen; C1-C3-alkyl, C1-C3-alkoxy, C2-C3 alkenyl, C2-C3-alkynyl (these groups are unsubstituted or substituted with halogen). In another embodiment, each R X is, independently, halogen, C1-C3-alkyl, or C1-C3-haloalkyl.

[0195] The exponent m is 0, 1, or 2. In one embodiment, the exponent m is 2. In another embodiment, the exponent m is 0. The exponent n is 0, 1, 2, or 3. In one embodiment, the exponent n is 2. In another embodiment, the exponent n is 3.

[0196] The variable element G represents a 5-membered or 6-membered saturated, partially unsaturated or fully unsaturated carbocyclic or heterocyclic ring, which carbocyclic or heterocyclic ring contains atoms E and J as ring members and is unsubstituted or substituted with one or more identical or different substituents R 9 and the heterocyclic ring contains, in addition to those which may be present as ring members E and J, zero, one or more identical or different heteroatoms O, N or S as ring members.

[0197] In one embodiment, the variable element G represents a 6-membered saturated, partially unsaturated or fully unsaturated carbocyclic or heterocyclic ring, which carbocyclic or heterocyclic ring contains atoms E and J as ring members and is unsubstituted or substituted with one or more identical or different substituents R 9 and the heterocyclic ring contains, in addition to those which may be present as ring members E and J, zero, one or more identical or different heteroatoms O, N or S as ring members. In one embodiment, the variable element G represents a 6-membered saturated, partially unsaturated or fully unsaturated carbocyclic or heterocyclic ring, which carbocyclic or heterocyclic ring contains atoms E and J as ring members and is unsubstituted or substituted with one or more identical or different substituents R9 is replaced, and in addition to those that can exist as ring members E and J, the heterocyclic ring contains 0, 1 or more N atoms as ring members.

[0198] In one embodiment, the variable element G represents a 6-membered saturated, partially unsaturated or fully unsaturated carbocyclic or heterocyclic ring, which carbocyclic or heterocyclic ring contains atoms E and J as ring members and is unsubstituted or substituted with 0, 1 or more of the same or different substituents R 9 is replaced, and in addition to those that can exist as ring members E and J, the heterocyclic ring contains 0, 1 or more N atoms as ring members.

[0199] In another embodiment, the variable element G represents a 6-membered partially or fully unsaturated carbocyclic ring, which carbocyclic ring contains atoms E and J as ring members and is unsubstituted or substituted with one or more of the same or different substituents R 9 is substituted.

[0200] In another embodiment, the variable element G represents a 6-membered partially or fully unsaturated heterocyclic ring, which heterocyclic ring contains atoms E and J as ring members and is unsubstituted or substituted with one or more of the same or different substituents R 9 is replaced, and in addition to those that can exist as ring members E and J, the heterocyclic ring contains 0, 1 or more of the same or different heteroatoms O, N or S as ring members.

[0201] In one embodiment, the variable element G represents a 5-membered saturated, partially unsaturated or fully unsaturated carbocyclic or heterocyclic ring, which carbocyclic or heterocyclic ring contains atoms E and J as ring members and is unsubstituted or substituted with one or more of the same or different substituents R 9 is replaced, and in addition to those that can exist as ring members E and J, the heterocyclic ring contains 0, 1 or more of the same or different heteroatoms O, N or S. In another embodiment, the variable element G represents a 5-membered partially or fully unsaturated carbocyclic ring, which carbocyclic ring contains atoms E and J as ring members and is unsubstituted or substituted with one or more of the same or different substituents R 9It is replaced by. In another embodiment, the variable element G represents a 5-membered partial or fully unsaturated heterocyclic ring, which heterocyclic ring contains atoms E and J as ring members and is unsubstituted or substituted with one or more of the same or different substituents R 9 and is substituted, and in addition to those that can exist as ring members E and J, the heterocyclic ring contains zero, one or more of the same or different heteroatoms O, N or S.

[0202] The variable element A is N, S, O, CR 7 , or NR 8 . In one embodiment, the variable element A is N. In another embodiment, the variable element A is NR 8 . In another embodiment, the variable element A is O. In another embodiment, the variable element A is S.

[0203] The variable elements E, J are independently C or N, and at least one of the variable elements selected from E and J is C. In one embodiment, E is N and J is C. In another embodiment, J is N and E is C.

[0204] In another embodiment, A and E are N and J is C. In another embodiment, A and J are N and E is C.

[0205] Accordingly, the fused bicyclic ring D can be represented by Formulas D1 to D51

[0206]

Chemical formula

[0207] R 9 The position of can be illustrated by the following scheme. Formulas (D.A) and (D.B) show alternative examples of ring G which is a 6-membered ring or a 5-membered ring, respectively

[0208]

Chemical formula

[0209] Therefore, for the substituent R of rings D1 to D51 9 the position x is indicated by the subscript ".x", for example D1.1, D1.2, D1.3, or D1.4.

[0210] For example, a fused bicyclic ring D1 having one substituent R at the 2-position 9 corresponds to ring (D1.2).

[0211]

Chemical formula

[0212] The following Tables 1 to 266 correspond to specific ring systems as combinations of the bicyclic fused ring D and the bicyclic fused ring (I-A) or (I-B).

[0213] Table 1: Compounds of formula (I.A) wherein variable element D is of formula (D1.1). Table 2: Compounds of formula (I.A) wherein variable element D is of formula (D1.2). Table 3: Compounds of formula (I.A) wherein variable element D is of formula (D1.3). Table 4: Compounds of formula (I.A) wherein variable element D is of formula (D1.4). Table 5: Compounds of formula (I.A) wherein variable element D is of formula (D2.1). Table 6: Compounds of formula (I.A) wherein variable element D is of formula (D2.2). Table 7: Compounds of formula (I.A) wherein variable element D is of formula (D2.3). Table 8: Compounds of formula (I.A) wherein variable element D is of formula (D2.4). Table 9: Compounds of formula (I.A) wherein variable element D is of formula (D3.1). Table 10: Compounds of formula (I.A) wherein variable element D is of formula (D3.2). Table 11: Compounds of formula (I.A) wherein variable element D is of formula (D3.3). Table 12: Compounds of formula (I.A) wherein variable element D is of formula (D3.4). Table 13: Compounds of formula (I.A) wherein variable element D is of formula (D4.1). Table 14: Compounds of formula (I.A) wherein variable element D is of formula (D4.2). Table 15: Compounds of formula (I.A) wherein variable element D is of formula (D4.3). Table 16: Compounds of formula (I.A) wherein variable element D is of formula (D4.4). Table 17: Compounds of formula (I.A) wherein variable element D is of formula (D5.1). Table 18: Compounds of formula (I.A) wherein variable element D is of formula (D5.2). Table 19: Compounds of formula (I.A) wherein variable element D is of formula (D5.3). Table 20: Compounds of formula (I.A) wherein variable element D is of formula (D5.4). Table 21: Compounds of formula (I.A) in which variable element D is of formula (D6.1). Table 22: Compounds of formula (I.A) in which variable element D is of formula (D6.2). Table 23: Compounds of formula (I.A) in which variable element D is of formula (D6.3). Table 24: Compounds of formula (I.A) in which variable element D is of formula (D6.4). Table 25: Compounds of formula (I.A) in which variable element D is of formula (D7.1). Table 26: Compounds of formula (I.A) in which variable element D is of formula (D7.2). Table 27: Compounds of formula (I.A) in which variable element D is of formula (D7.3). Table 28: Compounds of formula (I.A) in which variable element D is of formula (D7.4). Table 29: Compounds of formula (I.A) in which variable element D is of formula (D8.1). Table 30: Compounds of formula (I.A) in which variable element D is of formula (D8.2). Table 31: Compounds of formula (I.A) in which variable element D is of formula (D8.3). Table 32: Compounds of formula (I.A) in which variable element D is of formula (D9.1). Table 33: Compounds of formula (I.A) in which variable element D is of formula (D9.2). Table 34: Compounds of formula (I.A) in which variable element D is of formula (D9.3). Table 35: Compounds of formula (I.A) in which variable element D is of formula (D10.1). Table 36: Compounds of formula (I.A) in which variable element D is of formula (D10.2). Table 37: Compounds of formula (I.A) in which variable element D is of formula (D10.3). Table 38: Compounds of formula (I.A) in which variable element D is of formula (D11.1). Table 39: Compounds of formula (I.A) in which variable element D is of formula (D11.2). Table 40: Compounds of formula (I.A) in which variable element D is of formula (D11.3). Table 41: Compounds of formula (I.A) in which variable element D is of formula (D11.4). Table 42: Compounds of formula (I.A) in which variable element D is of formula (D12.1). Table 43: Compounds of formula (I.A) in which variable element D is of formula (D12.2). Table 44: Compounds of formula (I.A) in which variable element D is of formula (D12.3). Table 45: Compounds of formula (I.A) in which variable element D is of formula (D13.1). Table 46: Compounds of formula (I.A) in which variable element D is of formula (D13.2). Table 47: Compounds of formula (I.A) in which variable element D is of formula (D13.3). Table 48: Compounds of formula (I.A) in which variable element D is of formula (D14.1). Table 49: Compounds of formula (I.A) in which variable element D is of formula (D14.2). Table 50: Compounds of formula (I.A) in which variable element D is of formula (D14.3). Table 51: Compounds of formula (I.A) in which variable element D is of formula (D15.1). Table 52: Compounds of formula (I.A) in which variable element D is of formula (D15.2). Table 53: Compounds of formula (I.A) in which variable element D is of formula (D15.4). Table 54: Compounds of formula (I.A) in which variable element D is of formula (D16.1). Table 55: Compounds of formula (I.A) in which variable element D is of formula (D16.2). Table 56: Compounds of formula (I.A) in which variable element D is of formula (D16.4). Table 57: Compounds of formula (I.A) in which variable element D is of formula (D17.1). Table 58: Compounds of formula (I.A) in which variable element D is of formula (D17.2). Table 59: Compounds of formula (I.A) in which variable element D is of formula (D17.4). Table 60: Compounds of formula (I.A) in which variable element D is of formula (D18.1). Table 61: Compounds of formula (I.A) in which variable element D is of formula (D18.2). Table 62: Compounds of formula (I.A) in which variable element D is of formula (D18.3). Table 63: Compounds of formula (I.A) in which variable element D is of formula (D18.4). Table 64: Compounds of formula (I.A) in which variable element D is of formula (D19.1). Table 65: Compounds of formula (I.A) in which variable element D is of formula (D19.2). Table 66: Compounds of formula (I.A) in which variable element D is of formula (D19.3). Table 67: Compounds of formula (I.A) in which variable element D is of formula (D19.4). Table 68: Compounds of formula (I.A) in which variable element D is of formula (D20.1). Table 69: Compounds of formula (I.A) in which variable element D is of formula (D20.2). Table 70: Compounds of formula (I.A) in which variable element D is of formula (D20.3). Table 71: Compounds of formula (I.A) in which variable element D is of formula (D20.4). Table 72: Compounds of formula (I.A) in which variable element D is of formula (D21.1). Table 73: Compounds of formula (I.A) in which variable element D is of formula (D21.2). Table 74: Compounds of formula (I.A) in which variable element D is of formula (D21.4). Table 75: Compounds of formula (I.A) in which variable element D is of formula (D22.1). Table 76: Compounds of formula (I.A) in which variable element D is of formula (D22.3). Table 77: Compounds of formula (I.A) in which variable element D is of formula (D22.4). Table 78: Compounds of formula (I.A) in which variable element D is of formula (D23.1). Table 79: Compounds of formula (I.A) in which variable element D is of formula (D23.3). Table 80: Compounds of formula (I.A) in which variable element D is of formula (D23.4). Table 81: Compounds of formula (I.A) in which variable element D is of formula (D24.1). Table 82: Compounds of formula (I.A) in which variable element D is of formula (D24.3). Table 83: Compounds of formula (I.A) in which variable element D is of formula (D24.4). Table 84: Compounds of formula (I.A) in which variable element D is of formula (D25.1). Table 85: Compounds of formula (I.A) in which variable element D is of formula (D25.2). Table 86: Compounds of formula (I.A) in which variable element D is of formula (D25.3). Table 87: Compounds of formula (I.A) in which variable element D is of formula (D25.4). Table 88: Compounds of formula (I.A) in which variable element D is of formula (D26.1). Table 89: Compounds of formula (I.A) in which variable element D is of formula (D26.3). Table 90: Compounds of formula (I.A) in which variable element D is of formula (D26.4). Table 91: Compounds of formula (I.A) in which variable element D is of formula (D27.1). Table 92: Compounds of formula (I.A) in which variable element D is of formula (D27.3). Table 93: Compounds of formula (I.A) in which variable element D is of formula (D27.4). Table 94: Compounds of formula (I.A) in which variable element D is of formula (D28.1). Table 95: Compounds of formula (I.A) in which variable element D is of formula (D28.3). Table 96: Compounds of formula (I.A) in which variable element D is of formula (D28.4). Table 97: Compounds of formula (I.A) in which variable element D is of formula (D29.2). Table 98: Compounds of formula (I.A) in which variable element D is of formula (D29.3). Table 99: Compounds of formula (I.A) in which variable element D is of formula (D29.4). Table 100: Compounds of formula (I.A) in which variable element D is of formula (D30.2). Table 101: Compounds of formula (I.A) in which variable element D is of formula (D30.3). Table 102: Compounds of formula (I.A) in which variable element D is of formula (D30.4). Table 103: Compounds of formula (I.A) in which variable element D is of formula (D31.2). Table 104: Compounds of formula (I.A) in which variable element D is of formula (D31.3). Table 105: Compounds of formula (I.A) in which variable element D is of formula (D31.4). Table 106: Compounds of formula (I.A) in which variable element D is of formula (D32.1). Table 107: Compounds of formula (I.A) in which variable element D is of formula (D32.2). Table 108: Compounds of formula (I.A) in which variable element D is of formula (D32.3). Table 109: Compounds of formula (I.A) in which variable element D is of formula (D32.4). Table 110: Compounds of formula (I.A) in which variable element D is of formula (D33.2). Table 111: Compounds of formula (I.A) in which variable element D is of formula (D33.3). Table 112: Compounds of formula (I.A) in which variable element D is of formula (D33.4). Table 113: Compounds of formula (I.A) in which variable element D is of formula (D34.2). Table 114: Compounds of formula (I.A) in which variable element D is of formula (D34.3). Table 115: Compounds of formula (I.A) in which variable element D is of formula (D34.4). Table 116: Compounds of formula (I.A) in which variable element D is of formula (D35.2). Table 117: Compounds of formula (I.A) in which variable element D is of formula (D35.3). Table 118: Compounds of formula (I.A) in which variable element D is of formula (D35.4). Table 119: Compounds of formula (I.A) in which variable element D is of formula (D36.1). Table 120: Compounds of formula (I.A) in which variable element D is of formula (D36.2). Table 121: Compounds of formula (I.A) in which variable element D is of formula (D37.1). Table 122: Compounds of formula (I.A) in which variable element D is of formula (D37.2). Table 123: Compounds of formula (I.A) in which variable element D is of formula (D38.2). Table 124: Compounds of formula (I.A) in which variable element D is of formula (D39.2). Table 125: Compounds of formula (I.A) in which variable element D is of formula (D40.1). Table 126: Compounds of formula (I.A) in which variable element D is of formula (D40.2). Table 127: Compounds of formula (I.A) in which variable element D is of formula (D41.1). Table 128: Compounds of formula (I.A) in which variable element D is of formula (D41.2). Table 129: Compounds of formula (I.A) in which variable element D is of formula (D42.2). Table 130: Compounds of formula (I.A) in which variable element D is of formula (D43.2). Table 131: Compounds of formula (I.A) in which variable element D is of formula (D44.2). Table 132: Compounds of formula (I.A) in which variable element D is of formula (D45.2). Table 133: Compounds of formula (I.A) in which variable element D is of formula (D46.2). Table 134: Compounds of formula (I.A) in which variable element D is of formula (D47.2). Table 135: Compounds of formula (I.A) in which variable element D is of formula (D48.2). Table 136: Compounds of formula (I.A) in which variable element D is of formula (D49.2). Table 137: Compounds of formula (I.A) in which variable element D is of formula (D50). Table 138: Compounds of formula (I.A) in which variable element D is of formula (D51.1). Table 139: Compounds of formula (I.A) in which variable element D is of formula (D51.2). Table 140: Compounds of formula (I.A) in which variable element D is of formula (D51.3). Table 141: Compounds of formula (I.A) in which variable element D is of formula (D51.4). Table 142: Compounds of formula (I.B) in which variable element D is of formula (D1.1). Table 143: Compounds of formula (I.B) in which variable element D is of formula (D1.2). Table 144: Compounds of formula (I.B) in which variable element D is of formula (D1.3). Table 145: Compounds of formula (I.B) in which variable element D is of formula (D1.4). Table 146: Compounds of formula (I.B) in which variable element D is of formula (D2.1). Table 147: Compounds of formula (I.B) in which variable element D is of formula (D2.2). Table 148: Compounds of formula (I.B) in which variable element D is of formula (D2.3). Table 149: Compounds of formula (I.B) in which variable element D is of formula (D2.4). Table 150: Compounds of formula (I.B) in which variable element D is of formula (D3.1). Table 151: Compounds of formula (I.B) in which variable element D is of formula (D3.2). Table 152: Compounds of formula (I.B) in which variable element D is of formula (D3.3). Table 153: Compounds of formula (I.B) in which variable element D is of formula (D3.4). Table 154: Compounds of formula (I.B) in which variable element D is of formula (D4.1). Table 155: Compounds of formula (I.B) in which variable element D is of formula (D4.2). Table 156: Compounds of formula (I.B) in which variable element D is of formula (D4.3). Table 157: Compounds of formula (I.B) in which variable element D is of formula (D4.4). Table 158: Compounds of formula (I.B) in which variable element D is of formula (D5.1). Table 159: Compounds of formula (I.B) in which variable element D is of formula (D5.2). Table 160: Compounds of formula (I.B) in which variable element D is of formula (D5.3). Table 161: Compounds of formula (I.B) in which variable element D is of formula (D5.4). Table 162: Compounds of formula (I.B) in which variable element D is of formula (D6.1). Table 163: Compounds of formula (I.B) in which variable element D is of formula (D6.2). Table 164: Compounds of formula (I.B) in which variable element D is of formula (D6.3). Table 165: Compounds of formula (I.B) in which variable element D is of formula (D6.4). Table 166: Compounds of formula (I.B) in which variable element D is of formula (D7.1). Table 167: Compounds of formula (I.B) in which variable element D is of formula (D7.2). Table 168: Compounds of formula (I.B) in which variable element D is of formula (D7.3). Table 169: Compounds of formula (I.B) in which variable element D is of formula (D7.4). Table 170: Compounds of formula (I.B) in which variable element D is of formula (D8.1). Table 171: Compounds of formula (I.B) in which variable element D is of formula (D8.2). Table 172: Compounds of formula (I.B) in which variable element D is of formula (D8.3). Table 173: Compounds of formula (I.B) in which variable element D is of formula (D9.1). Table 174: Compounds of formula (I.B) in which variable element D is of formula (D9.2). Table 175: Compounds of formula (I.B) in which variable element D is of formula (D9.3). Table 176: Compounds of formula (I.B) in which variable element D is of formula (D10.1). Table 177: Compounds of formula (I.B) in which variable element D is of formula (D10.2). Table 178: Compounds of formula (I.B) in which variable element D is of formula (D10.3). Table 179: Compounds of formula (I.B) wherein variable element D is of formula (D11.1). Table 180: Compounds of formula (I.B) wherein variable element D is of formula (D11.2). Table 181: Compounds of formula (I.B) wherein variable element D is of formula (D11.3). Table 182: Compounds of formula (I.B) wherein variable element D is of formula (D11.4). Table 183: Compounds of formula (I.B) wherein variable element D is of formula (D12.1). Table 184: Compounds of formula (I.B) wherein variable element D is of formula (D12.2). Table 185: Compounds of formula (I.B) wherein variable element D is of formula (D12.3). Table 186: Compounds of formula (I.B) wherein variable element D is of formula (D13.1). Table 187: Compounds of formula (I.B) wherein variable element D is of formula (D13.2). Table 188: Compounds of formula (I.B) wherein variable element D is of formula (D13.3). Table 189: Compounds of formula (I.B) wherein variable element D is of formula (D14.1). Table 190: Compounds of formula (I.B) wherein variable element D is of formula (D14.2). Table 191: Compounds of formula (I.B) wherein variable element D is of formula (D14.3). Table 192: Compounds of formula (I.B) wherein variable element D is of formula (D15.1). Table 193: Compounds of formula (I.B) wherein variable element D is of formula (D15.2). Table 194: Compounds of formula (I.B) wherein variable element D is of formula (D15.4). Table 195: Compounds of formula (I.B) wherein variable element D is of formula (D16.1). Table 196: Compounds of formula (I.B) wherein variable element D is of formula (D16.2). Table 197: Compounds of formula (I.B) wherein variable element D is of formula (D16.4). Table 198: Compounds of formula (I.B) wherein variable element D is of formula (D17.1). Table 199: Compounds of formula (I.B) wherein variable element D is of formula (D17.2). Table 200: Compounds of formula (I.B) wherein variable element D is of formula (D17.4). Table 201: Compounds of formula (I.B) wherein variable element D is of formula (D18.1). Table 202: Compounds of formula (I.B) wherein variable element D is of formula (D18.2). Table 203: Compounds of formula (I.B) wherein variable element D is of formula (D18.3). Table 204: Compounds of formula (I.B) wherein variable element D is of formula (D18.4). Table 205: Compounds of formula (I.B) wherein variable element D is of formula (D19.1). Table 206: Compounds of formula (I.B) wherein variable element D is of formula (D19.2). Table 207: Compounds of formula (I.B) wherein variable element D is of formula (D19.3). Table 208: Compounds of formula (I.B) wherein variable element D is of formula (D19.4). Table 209: Compounds of formula (I.B) wherein variable element D is of formula (D20.1). Table 210: Compounds of formula (I.B) wherein variable element D is of formula (D20.2). Table 211: Compounds of formula (I.B) wherein variable element D is of formula (D20.3). Table 212: Compounds of formula (I.B) wherein variable element D is of formula (D20.4). Table 213: Compounds of formula (I.B) wherein variable element D is of formula (D21.1). Table 214: Compounds of formula (I.B) wherein variable element D is of formula (D21.2). Table 215: Compounds of formula (I.B) wherein variable element D is of formula (D21.4). Table 216: Compounds of formula (I.B) wherein variable element D is of formula (D22.1). Table 217: Compounds of formula (I.B) in which variable element D is of formula (D22.3). Table 218: Compounds of formula (I.B) in which variable element D is of formula (D22.4). Table 219: Compounds of formula (I.B) in which variable element D is of formula (D23.1). Table 220: Compounds of formula (I.B) in which variable element D is of formula (D23.3). Table 221: Compounds of formula (I.B) in which variable element D is of formula (D23.4). Table 222: Compounds of formula (I.B) in which variable element D is of formula (D24.1). Table 223: Compounds of formula (I.B) in which variable element D is of formula (D24.3). Table 224: Compounds of formula (I.B) in which variable element D is of formula (D24.4). Table 225: Compounds of formula (I.B) in which variable element D is of formula (D25.1). Table 226: Compounds of formula (I.B) in which variable element D is of formula (D25.2). Table 227: Compounds of formula (I.B) in which variable element D is of formula (D25.3). Table 228: Compounds of formula (I.B) in which variable element D is of formula (D25.4). Table 229: Compounds of formula (I.B) in which variable element D is of formula (D26.1). Table 230: Compounds of formula (I.B) in which variable element D is of formula (D26.3). Table 231: Compounds of formula (I.B) in which variable element D is of formula (D26.4). Table 232: Compounds of formula (I.B) in which variable element D is of formula (D27.1). Table 333: Compounds of formula (I.B) in which variable element D is of formula (D27.3). Table 234: Compounds of formula (I.B) in which variable element D is of formula (D27.4). Table 235: Compounds of formula (I.B) in which variable element D is of formula (D28.1). Table 236: Compounds of formula (I.B) in which variable element D is of formula (D28.3). Table 237: Compounds of formula (I.B) in which variable element D is of formula (D28.4). Table 238: Compounds of formula (I.B) in which variable element D is of formula (D29.2). Table 239: Compounds of formula (I.B) in which variable element D is of formula (D29.3). Table 240: Compounds of formula (I.B) in which variable element D is of formula (D29.4). Table 241: Compounds of formula (I.B) in which variable element D is of formula (D30.2). Table 242: Compounds of formula (I.B) in which variable element D is of formula (D30.3). Table 243: Compounds of formula (I.B) in which variable element D is of formula (D30.4). Table 244: Compounds of formula (I.B) in which variable element D is of formula (D31.2). Table 245: Compounds of formula (I.B) in which variable element D is of formula (D31.3). Table 246: Compounds of formula (I.B) in which variable element D is of formula (D31.4). Table 247: Compounds of formula (I.B) in which variable element D is of formula (D32.1). Table 248: Compounds of formula (I.B) in which variable element D is of formula (D32.2). Table 249: Compounds of formula (I.B) in which variable element D is of formula (D32.3). Table 250: Compounds of formula (I.B) in which variable element D is of formula (D32.4). Table 251: Compounds of formula (I.B) in which variable element D is of formula (D33.2). Table 252: Compounds of formula (I.B) in which variable element D is of formula (D33.3). Table 253: Compounds of formula (I.B) in which variable element D is of formula (D33.4). Table 254: Compounds of formula (I.B) in which variable element D is of formula (D34.2). Table 255: Compounds of formula (I.B) where the variable element D is of formula (D34.3). Table 256: Compounds of formula (I.B) where the variable element D is of formula (D34.4). Table 257: Compounds of formula (I.B) where the variable element D is of formula (D35.2). Table 258: Compounds of formula (I.B) where the variable element D is of formula (D35.3). Table 259: Compounds of formula (I.B) where the variable element D is of formula (D35.4). Table 260: Compounds of formula (I.B) where the variable element D is of formula (D36.1). Table 261: Compounds of formula (I.B) where the variable element D is of formula (D36.2). Table 262: Compounds of formula (I.B) where the variable element D is of formula (D37.1). Table 263: Compounds of formula (I.B) where the variable element D is of formula (D37.2). Table 264: Compounds of formula (I.B) where the variable element D is of formula (D38.2). Table 265: Compounds of formula (I.B) where the variable element D is of formula (D39.2). Table 266: Compounds of formula (I.B) where the variable element D is of formula (D40.1). Table 267: Compounds of formula (I.B) where the variable element D is of formula (D40.2). Table 268: Compounds of formula (I.B) where the variable element D is of formula (D41.1). Table 269: Compounds of formula (I.B) where the variable element D is of formula (D41.2). Table 270: Compounds of formula (I.B) where the variable element D is of formula (D42.2). Table 271: Compounds of formula (I.B) where the variable element D is of formula (D43.2). Table 272: Compounds of formula (I.B) where the variable element D is of formula (D44.2). Table 273: Compounds of formula (I.B) where the variable element D is of formula (D45.2). Table 274: Compounds of formula (I.B) in which variable element D is of formula (D46.2). Table 275: Compounds of formula (I.B) in which variable element D is of formula (D47.2). Table 276: Compounds of formula (I.B) in which variable element D is of formula (D48.2). Table 277: Compounds of formula (I.B) in which variable element D is of formula (D49.2). Table 278: Compounds of formula (I.B) in which variable element D is of formula (D50). Table 279: Compounds of formula (I.B) in which variable element D is of formula (D51.1). Table 280: Compounds of formula (I.B) in which variable element D is of formula (D51.2). Table 281: Compounds of formula (I.B) in which variable element D is of formula (D51.3). Table 282: Compounds of formula (I.B) in which variable element D is of formula (D51.4). Table 283: Compounds of formula (I.C) in which variable element D is of formula (D1.1). Table 284: Compounds of formula (I.C) in which variable element D is of formula (D1.2). Table 285: Compounds of formula (I.C) in which variable element D is of formula (D1.3). Table 286: Compounds of formula (I.C) in which variable element D is of formula (D1.4). Table 287: Compounds of formula (I.C) in which variable element D is of formula (D2.1). Table 288: Compounds of formula (I.C) in which variable element D is of formula (D2.2). Table 289: Compounds of formula (I.C) in which variable element D is of formula (D2.3). Table 290: Compounds of formula (I.C) in which variable element D is of formula (D2.4). Table 291: Compounds of formula (I.C) in which variable element D is of formula (D3.1). Table 292: Compounds of formula (I.C) in which variable element D is of formula (D3.2). Table 293: Compounds of formula (I.C) in which variable element D is of formula (D3.3). Table 294: Compounds of formula (I.C) in which variable element D is of formula (D3.4). Table 295: Compounds of formula (I.C) in which variable element D is of formula (D4.1). Table 296: Compounds of formula (I.C) in which variable element D is of formula (D4.2). Table 297: Compounds of formula (I.C) in which variable element D is of formula (D4.3). Table 298: Compounds of formula (I.C) in which variable element D is of formula (D4.4). Table 299: Compounds of formula (I.C) in which variable element D is of formula (D5.1). Table 300: Compounds of formula (I.C) in which variable element D is of formula (D5.2). Table 301: Compounds of formula (I.C) in which variable element D is of formula (D5.3). Table 302: Compounds of formula (I.C) in which variable element D is of formula (D5.4). Table 303: Compounds of formula (I.C) in which variable element D is of formula (D6.1). Table 304: Compounds of formula (I.C) in which variable element D is of formula (D6.2). Table 305: Compounds of formula (I.C) in which variable element D is of formula (D6.3). Table 306: Compounds of formula (I.C) in which variable element D is of formula (D6.4). Table 307: Compounds of formula (I.C) in which variable element D is of formula (D7.1). Table 308: Compounds of formula (I.C) in which variable element D is of formula (D7.2). Table 309: Compounds of formula (I.C) in which variable element D is of formula (D7.3). Table 310: Compounds of formula (I.C) in which variable element D is of formula (D7.4). Table 311: Compounds of formula (I.C) in which variable element D is of formula (D8.1). Table 312: Compounds of formula (I.C) in which variable element D is of formula (D8.2). Table 313: Compounds of formula (I.C) in which variable element D is of formula (D8.3). Table 314: Compounds of formula (I.C) in which variable element D is of formula (D9.1). Table 315: Compounds of formula (I.C) in which variable element D is of formula (D9.2). Table 316: Compounds of formula (I.C) in which variable element D is of formula (D9.3). Table 317: Compounds of formula (I.C) in which variable element D is of formula (D10.1). Table 318: Compounds of formula (I.C) in which variable element D is of formula (D10.2). Table 319: Compounds of formula (I.C) in which variable element D is of formula (D10.3). Table 320: Compounds of formula (I.C) in which variable element D is of formula (D11.1). Table 321: Compounds of formula (I.C) in which variable element D is of formula (D11.2). Table 322: Compounds of formula (I.C) in which variable element D is of formula (D11.3). Table 323: Compounds of formula (I.C) in which variable element D is of formula (D11.4). Table 324: Compounds of formula (I.C) in which variable element D is of formula (D12.1). Table 325: Compounds of formula (I.C) in which variable element D is of formula (D12.2). Table 326: Compounds of formula (I.C) in which variable element D is of formula (D12.3). Table 327: Compounds of formula (I.C) in which variable element D is of formula (D13.1). Table 328: Compounds of formula (I.C) in which variable element D is of formula (D13.2). Table 329: Compounds of formula (I.C) in which variable element D is of formula (D13.3). Table 330: Compounds of formula (I.C) in which variable element D is of formula (D14.1). Table 331: Compounds of formula (I.C) in which variable element D is of formula (D14.2). Table 332: Compounds of formula (I.C) in which variable element D is of formula (D14.3). Table 333: Compounds of formula (I.C) in which variable element D is of formula (D15.1). Table 334: Compounds of formula (I.C) in which variable element D is of formula (D15.2). Table 335: Compounds of formula (I.C) in which variable element D is of formula (D15.4). Table 336: Compounds of formula (I.C) in which variable element D is of formula (D16.1). Table 337: Compounds of formula (I.C) in which variable element D is of formula (D16.2). Table 338: Compounds of formula (I.C) in which variable element D is of formula (D16.4). Table 339: Compounds of formula (I.C) in which variable element D is of formula (D17.1). Table 340: Compounds of formula (I.C) in which variable element D is of formula (D17.2). Table 341: Compounds of formula (I.C) in which variable element D is of formula (D17.4). Table 342: Compounds of formula (I.C) in which variable element D is of formula (D18.1). Table 343: Compounds of formula (I.C) in which variable element D is of formula (D18.2). Table 344: Compounds of formula (I.C) in which variable element D is of formula (D18.3). Table 345: Compounds of formula (I.C) in which variable element D is of formula (D18.4). Table 346: Compounds of formula (I.C) in which variable element D is of formula (D19.1). Table 347: Compounds of formula (I.C) in which variable element D is of formula (D19.2). Table 348: Compounds of formula (I.C) in which variable element D is of formula (D19.3). Table 349: Compounds of formula (I.C) in which variable element D is of formula (D19.4). Table 350: Compounds of formula (I.C) in which variable element D is of formula (D20.1). Table 351: Compounds of formula (I.C) in which variable element D is of formula (D20.2). Table 352: Compounds of formula (I.C) in which variable element D is of formula (D20.3). Table 353: Compounds of formula (I.C) in which variable element D is of formula (D20.4). Table 354: Compounds of formula (I.C) in which variable element D is of formula (D21.1). Table 355: Compounds of formula (I.C) in which variable element D is of formula (D21.2). Table 356: Compounds of formula (I.C) in which variable element D is of formula (D21.4). Table 357: Compounds of formula (I.C) in which variable element D is of formula (D22.1). Table 358: Compounds of formula (I.C) in which variable element D is of formula (D22.3). Table 359: Compounds of formula (I.C) in which variable element D is of formula (D22.4). Table 360: Compounds of formula (I.C) in which variable element D is of formula (D23.1). Table 361: Compounds of formula (I.C) in which variable element D is of formula (D23.3). Table 362: Compounds of formula (I.C) in which variable element D is of formula (D23.4). Table 363: Compounds of formula (I.C) in which variable element D is of formula (D24.1). Table 364: Compounds of formula (I.C) in which variable element D is of formula (D24.3). Table 365: Compounds of formula (I.C) in which variable element D is of formula (D24.4). Table 366: Compounds of formula (I.C) in which variable element D is of formula (D25.1). Table 367: Compounds of formula (I.C) in which variable element D is of formula (D25.2). Table 368: Compounds of formula (I.C) in which variable element D is of formula (D25.3). Table 369: Compounds of formula (I.C) in which variable element D is of formula (D25.4). Table 370: Compounds of formula (I.C) in which variable element D is of formula (D26.1). Table 371: Compounds of formula (I.C) where variable element D is of formula (D26.3). Table 372: Compounds of formula (I.C) where variable element D is of formula (D26.4). Table 373: Compounds of formula (I.C) where variable element D is of formula (D27.1). Table 374: Compounds of formula (I.C) where variable element D is of formula (D27.3). Table 375: Compounds of formula (I.C) where variable element D is of formula (D27.4). Table 376: Compounds of formula (I.C) where variable element D is of formula (D28.1). Table 377: Compounds of formula (I.C) where variable element D is of formula (D28.3). Table 378: Compounds of formula (I.C) where variable element D is of formula (D28.4). Table 379: Compounds of formula (I.C) where variable element D is of formula (D29.2). Table 380: Compounds of formula (I.C) where variable element D is of formula (D29.3). Table 381: Compounds of formula (I.C) where variable element D is of formula (D29.4). Table 382: Compounds of formula (I.C) where variable element D is of formula (D30.2). Table 383: Compounds of formula (I.C) where variable element D is of formula (D30.3). Table 384: Compounds of formula (I.C) where variable element D is of formula (D30.4). Table 385: Compounds of formula (I.C) where variable element D is of formula (D31.2). Table 386: Compounds of formula (I.C) where variable element D is of formula (D31.3). Table 387: Compounds of formula (I.C) where variable element D is of formula (D31.4). Table 388: Compounds of formula (I.C) where variable element D is of formula (D32.1). Table 389: Compounds of formula (I.C) where variable element D is of formula (D32.2). Table 390: Compounds of formula (I.C) in which variable element D is of formula (D32.3). Table 391: Compounds of formula (I.C) in which variable element D is of formula (D32.4). Table 392: Compounds of formula (I.C) in which variable element D is of formula (D33.2). Table 393: Compounds of formula (I.C) in which variable element D is of formula (D33.3). Table 394: Compounds of formula (I.C) in which variable element D is of formula (D33.4). Table 395: Compounds of formula (I.C) in which variable element D is of formula (D34.2). Table 396: Compounds of formula (I.C) in which variable element D is of formula (D34.3). Table 397: Compounds of formula (I.C) in which variable element D is of formula (D34.4). Table 398: Compounds of formula (I.C) in which variable element D is of formula (D35.2). Table 399: Compounds of formula (I.C) in which variable element D is of formula (D35.3). Table 400: Compounds of formula (I.C) in which variable element D is of formula (D35.4). Table 401: Compounds of formula (I.C) in which variable element D is of formula (D36.1). Table 402: Compounds of formula (I.C) in which variable element D is of formula (D36.2). Table 403: Compounds of formula (I.C) in which variable element D is of formula (D37.1). Table 404: Compounds of formula (I.C) in which variable element D is of formula (D37.2). Table 405: Compounds of formula (I.C) in which variable element D is of formula (D38.2). Table 406: Compounds of formula (I.C) in which variable element D is of formula (D39.2). Table 407: Compounds of formula (I.C) in which variable element D is of formula (D40.1). Table 408: Compounds of formula (I.C) in which variable element D is of formula (D40.2). Table 409: Compounds of formula (I.C) in which variable element D is of formula (D41.1). Table 410: Compounds of formula (I.C) in which variable element D is of formula (D41.2). Table 411: Compounds of formula (I.C) in which variable element D is of formula (D42.2). Table 412: Compounds of formula (I.C) in which variable element D is of formula (D43.2). Table 413: Compounds of formula (I.C) in which variable element D is of formula (D44.2). Table 414: Compounds of formula (I.C) in which variable element D is of formula (D45.2). Table 415: Compounds of formula (I.C) in which variable element D is of formula (D46.2). Table 416: Compounds of formula (I.C) in which variable element D is of formula (D47.2). Table 417: Compounds of formula (I.C) in which variable element D is of formula (D48.2). Table 418: Compounds of formula (I.C) in which variable element D is of formula (D49.2). Table 419: Compounds of formula (I.C) in which variable element D is of formula (D50). Table 420: Compounds of formula (I.C) in which variable element D is of formula (D50.1). Table 421: Compounds of formula (I.C) in which variable element D is of formula (D50.2). Table 422: Compounds of formula (I.C) in which variable element D is of formula (D50.3). Table 423: Compounds of formula (I.C) in which variable element D is of formula (D50.4).

[0214] The following Table A shows specific combinations of the definitions of the substituents X, R 2 , R 3 , and R 9 in columns A1 to A480. Each combination individually, and all combinations collectively, represent preferred embodiments.

[0215] [Table 1] TIFF0007692906000033.tif255158TIFF0007692906000034.tif254160TIFF0007692906000035.tif254158TIFF0007692906000036.tif254162TIFF0007692906000037.tif254160TIFF0007692906000038.tif255160TIFF0007692906000039.tif255162TIFF0007692906000040.tif254161TIFF0007692906000041.tif59168

[0216] The following Embodiments 1 to 574 represent specific combinations of all substituents and table definitions. Each combination individually, and all combinations collectively, represent preferred embodiments.

[0217] Embodiment 1: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 1, and R 2 , R 3 , X, and R 9 have the meanings defined in rows A1 to A480 of Table A. Embodiment 2: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 2, and R 2 , R 3 , X, and R 9 have the meanings defined in rows A1 to A480 of Table A. Embodiment 3: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7and R 8 is, when present, H, the ring system is represented by Table 3, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 4: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 4, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 5: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 5, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 6: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 6, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 7: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 7, and R 2 , R 3 , X and R9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 8: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is H, if present, the ring system is represented by Table 8, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 9: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is H, if present, the ring system is represented by Table 9, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 10: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is H, if present, the ring system is represented by Table 10, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 11: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is H, if present, the ring system is represented by Table 11, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 12: R 1is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is H, if present, the ring system is represented by Table 12, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 13: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is H, if present, the ring system is represented by Table 13, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 14: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is H, if present, the ring system is represented by Table 14, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 15: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is H, if present, the ring system is represented by Table 15, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 16: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R7 and R 8 is, when present, H, the ring system is represented by Table 16, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 17: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 17, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 18: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 18, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 19: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 19, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 20: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 20, and R 2 , R3 、 X, and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 21: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 21, and R 2 、 R 3 、 X, and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 22: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 22, and R 2 、 R 3 、 X, and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 23: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 23, and R 2 、 R 3 、 X, and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 24: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 24, and R 2 、 R 3 、 X, and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 25: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 25, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 26: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 26, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 27: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 27, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 28: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 28, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 29: R 1 is CF3, and R 6 is CH3; R Wis CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 29, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 30: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 30, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 31: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 31, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 32: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 32, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 33: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8is, when present, H, the ring system is represented by Table 33, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 34: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 34, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 35: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 35, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 36: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 36, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 37: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 37, and R 2 , R 3 , X and R9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 38: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 38, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 39: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 39, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 40: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 40, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 41: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 41, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 42: R 1is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, the ring system is represented by Table 42, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 43: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, the ring system is represented by Table 43, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 44: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, the ring system is represented by Table 44, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 45: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, the ring system is represented by Table 45, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 46: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R7 and R 8 is, when present, H, the ring system is represented by Table 46, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 47: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 47, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 48: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 48, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 49: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 49, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 50: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 50, and R 2 , R3 , X, and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 51: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 51, and R 2 , R 3 , X, and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 52: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 52, and R 2 , R 3 , X, and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 53: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 53, and R 2 , R 3 , X, and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 54: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 54, and R 2 , R 3 , X, and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 55: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 55, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 56: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 56, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 57: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 57, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 58: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 58, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 59: R 1 is CF3, and R 6 is CH3; R Wis CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, the ring system is represented by Table 59, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 60: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, the ring system is represented by Table 60, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 61: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, the ring system is represented by Table 61, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 62: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, the ring system is represented by Table 62, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 63: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8is, when present, H, the ring system is represented by Table 63, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 64: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 64, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 65: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 65, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 66: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 66, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 67: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 67, and R 2 , R 3 , X and R9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 68: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is H, if present, the ring system is represented by Table 68, and R 2 、R 3 、X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 69: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is H, if present, the ring system is represented by Table 69, and R 2 、R 3 、X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 70: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is H, if present, the ring system is represented by Table 70, and R 2 、R 3 、X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 71: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is H, if present, the ring system is represented by Table 71, and R 2 、R 3 、X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 72: R 1is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, the ring system is represented by Table 72, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 73: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, the ring system is represented by Table 73, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 74: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, the ring system is represented by Table 74, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 75: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, the ring system is represented by Table 75, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 76: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R7 and R 8 is, when present, H, the ring system is represented by Table 76, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 77: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 77, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 78: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 78, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 79: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 79, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 80: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 80, and R 2 , R3 、 X, and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 81: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 81, and R 2 、 R 3 、 X, and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 82: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 82, and R 2 、 R 3 、 X, and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 83: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 83, and R 2 、 R 3 、 X, and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 84: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 84, and R 2 、 R 3 、 X, and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 85: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 85, and R 2 , R 3 , X, and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 86: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 86, and R 2 , R 3 , X, and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 87: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 87, and R 2 , R 3 , X, and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 88: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 88, and R 2 , R 3 , X, and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 89: R 1 is CF3, and R 6 is CH3; R Wis CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, the ring system is represented by Table 89, and R 2 and R 3 and X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 90: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, the ring system is represented by Table 90, and R 2 and R 3 and X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 91: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, the ring system is represented by Table 91, and R 2 and R 3 and X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 92: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, the ring system is represented by Table 92, and R 2 and R 3 and X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 93: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8is, when present, H, the ring system is represented by Table 93, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 94: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 94, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 95: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 95, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 96: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 96, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 97: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 97, and R 2 , R 3 , X and R9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 98: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, the ring system is represented by Table 98, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 99: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, the ring system is represented by Table 99, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 100: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, the ring system is represented by Table 100, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 101: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, the ring system is represented by Table 101, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 102: R1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 102, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 103: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 103, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 104: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 104, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 105: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 105, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 106: R 1 is CF3, and R 6 is CH3; R Wis CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 106, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 107: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 107, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 108: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 108, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 109: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 109, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 110: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8is, when present, H, the ring system is represented by Table 110, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 111: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 111, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 112: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 112, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 113: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 113, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 114: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 114, and R 2 , R 3 , X and R9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 115: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, the ring system is represented by Table 115, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 116: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, the ring system is represented by Table 116, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 117: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, the ring system is represented by Table 117, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 118: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, the ring system is represented by Table 118, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 119: R1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 119, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 120: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 120, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 121: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 121, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 122: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 122, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 123: R 1 is CF3, and R 6 is CH3; R Wis CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 123, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 124: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 124, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 125: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 125, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 126: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 126, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 127: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8is, when present, H, the ring system is represented by Table 127, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 128: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 128, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 129: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 129, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 130: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 130, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 131: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 131, and R 2 , R 3 , X and R9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 132: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 132, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 133: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 133, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 134: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 134, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 135: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 135, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 136: R1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 136, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 137: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 137, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 138: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 138, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 139: R 1 is CF3, and R 6 is CH3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 139, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 140: R 1 is CF3, and R 6 is CH3; R Wis CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 140, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 141: R 1 is CF3, R 6 is CH3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 141, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 142: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 1, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 143: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 2, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 144: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8is, when present, H, the ring system is represented by Table 3, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 145: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 4, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 146: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 5, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 147: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 6, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 148: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 7, and R 2 , R 3 , X and R 9has the meaning defined in rows A1 - A480 of Table A. Embodiment 149: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 8, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 150: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 9, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 151: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 10, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 152: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 11, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 153: R 1 is CF3, R6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 12, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 154: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 13, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 155: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 14, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 156: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 15, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 157: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R8 is, when present, H, the ring system is represented by Table 16, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 158: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 17, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 159: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 18, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 160: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 19, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 161: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 20, and R 2 , R 3 , X and R9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 162: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 21, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 163: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 22, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 164: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 23, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 165: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 24, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 166: R 1is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 25, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 167: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 26, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 168: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 27, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 169: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 28, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 170: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7and R 8 is, when present, H, the ring system is represented by Table 29, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 171: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 30, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 172: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 31, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 173: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 32, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 174: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 33, and R 2 , R 3, X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 175: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, the ring system is represented by Table 34, and R 2 , R 3 , X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 176: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, the ring system is represented by Table 35, and R 2 , R 3 , X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 177: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, the ring system is represented by Table 36, and R 2 , R 3 , X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 178: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, the ring system is represented by Table 37, and R 2 , R 3 , X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 179: R 1is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, the ring system is represented by Table 38, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 180: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, the ring system is represented by Table 39, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 181: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, the ring system is represented by Table 40, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 182: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, the ring system is represented by Table 41, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 183: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7and R 8 is, when present, H, the ring system is represented by Table 42, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 184: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 43, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 185: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 44, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 186: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 45, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 187: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 46, and R 2 , R 3, X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 188: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is H, if present, the ring system is represented by Table 47, and R 2 , R 3 , X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 189: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is H, if present, the ring system is represented by Table 48, and R 2 , R 3 , X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 190: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is H, if present, the ring system is represented by Table 49, and R 2 , R 3 , X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 191: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is H, if present, the ring system is represented by Table 50, and R 2 , R 3 , X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 192: R 1is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 51, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 193: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 52, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 194: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 53, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 195: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 54, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 196: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7and R 8 is, when present, H, the ring system is represented by Table 55, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 197: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 56, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 198: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 57, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 199: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 58, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 200: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 59, and R 2 , R 3, X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 201: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is H if present, the ring system is represented by Table 60, and R 2 , R 3 , X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 202: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is H if present, the ring system is represented by Table 61, and R 2 , R 3 , X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 203: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is H if present, the ring system is represented by Table 62, and R 2 , R 3 , X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 204: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is H if present, the ring system is represented by Table 63, and R 2 , R 3 , X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 205: R 1is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 64, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 206: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 65, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 207: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 66, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 208: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 67, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 209: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7and R 8 is, when present, H, the ring system is represented by Table 68, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 210: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 69, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 211: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 70, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 212: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 71, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 213: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 72, and R 2 , R 3, X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 214: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, the ring system is represented by Table 73, and R 2 , R 3 , X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 215: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, the ring system is represented by Table 74, and R 2 , R 3 , X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 216: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, the ring system is represented by Table 75, and R 2 , R 3 , X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 217: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, the ring system is represented by Table 76, and R 2 , R 3 , X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 218: R 1is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 are, when present, H, the ring system is represented by Table 77, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 219: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 are, when present, H, the ring system is represented by Table 78, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 220: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 are, when present, H, the ring system is represented by Table 79, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 221: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 are, when present, H, the ring system is represented by Table 80, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 222: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7and R 8 is H, if present, the ring system is represented by Table 81, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 223: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is H, if present, the ring system is represented by Table 82, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 224: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is H, if present, the ring system is represented by Table 83, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 225: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is H, if present, the ring system is represented by Table 84, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 226: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is H, if present, the ring system is represented by Table 85, and R 2 , R 3, X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 227: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, the ring system is represented by Table 86, and R 2 , R 3 , X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 228: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, the ring system is represented by Table 87, and R 2 , R 3 , X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 229: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, the ring system is represented by Table 88, and R 2 , R 3 , X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 230: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, the ring system is represented by Table 89, and R 2 , R 3 , X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 231: R 1is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 90, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 232: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 91, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 233: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 92, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 234: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 93, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 235: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7and R 8 is, when present, H, the ring system is represented by Table 94, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 236: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 95, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 237: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 96, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 238: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 97, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 239: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 98, and R 2 , R 3, X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 240: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is H, if present, the ring system is represented by Table 99, and R 2 , R 3 , X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 241: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is H, if present, the ring system is represented by Table 100, and R 2 , R 3 , X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 242: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is H, if present, the ring system is represented by Table 101, and R 2 , R 3 , X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 243: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is H, if present, the ring system is represented by Table 102, and R 2 , R 3 , X, and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 244: R1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 103, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 245: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 104, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 246: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 105, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 247: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 106, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 248: R 1 is CF3, and R 6 is H; R Wis CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 107, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 249: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 108, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 250: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 109, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 251: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 110, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 252: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8is, when present, H, the ring system is represented by Table 111, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 253: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 112, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 254: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 113, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 255: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 114, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 256: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 115, and R 2 , R 3 , X and R9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 257: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 116, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 258: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 117, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 259: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 118, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 260: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 119, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 261: R 1is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 120, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 262: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 121, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 263: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 122, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 264: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 123, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 265: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R7 and R 8 is, when present, H, the ring system is represented by Table 124, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 266: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 125, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 267: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 126, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 268: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 127, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 269: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 128, and R 2, R 3 , X, and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 270: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, the ring system is represented by Table 129, and R 2 , R 3 , X, and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 271: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, the ring system is represented by Table 130, and R 2 , R 3 , X, and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 272: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, the ring system is represented by Table 131, and R 2 , R 3 , X, and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 273: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, the ring system is represented by Table 132, and R 2 , R 3 , X, and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 274: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 133, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 275: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 134, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 276: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 135, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 277: R 1 is CF3, and R 6 is H; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 136, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 278: R 1 is CF3, and R 6 is H; R Wis CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 137, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 279: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 138, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 280: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 139, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 281: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 140, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 282: R 1 is CF3, R 6 is H; R W is CH2CH3, the exponent m is 2, R 7 and R 8is, when present, H, the ring system is represented by Table 141, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 283: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is CH3, and the ring system is represented by Tables 142 - 282. Embodiment 284: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is CH3, and the ring system is represented by Tables 142 - 282. Embodiment 285: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is CH3, and the ring system is represented by Tables 142 - 282. Embodiment 286: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R9 is CH3, and the ring system is represented by Tables 142 - 282. Embodiment 287: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is CH3, and the ring system is represented by Tables 142 - 282. Embodiment 288: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is CH3, and the ring system is represented by Tables 142 - 282. Embodiment 289: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is CH3, and the ring system is represented by Tables 142 - 282. Embodiment 290: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is CH3, and the ring system is represented by Tables 142 - 282. Embodiment 291: R1 is CF3, and R 2 is H, and R 4 is H, and R 5 is H, X is O, and R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, and R 9 is CF3, and the ring system is represented by Tables 142 - 282. Embodiment 292: R 1 is CF3, and R 2 is CH3, and R 4 is H, and R 5 is H, X is O, and R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, and R 9 is CF3, and the ring system is represented by Tables 142 - 282. Embodiment 293: R 1 is CF3, and R 2 is H, and R 4 is H, and R 5 is CH3, X is O, and R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, and R 9 is CF3, and the ring system is represented by Tables 142 - 282. Embodiment 294: R 1 is CF3, and R 2 is CH3, and R 4 is H, and R 5 is CH3, X is O, and R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, and R 9 is CF3, and the ring system is represented by Tables 142 - 282. Embodiment 295: R 1 is CF3, and R 2 is H, and R 4 is H, and R5 is H, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is FH3, and the ring system is represented by Tables 142 - 282. Embodiment 296: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is CF3, and the ring system is represented by Tables 142 - 282. Embodiment 297: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is CF3, and the ring system is represented by Tables 142 - 282. Embodiment 298: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is CF3, and the ring system is represented by Tables 142 - 282. Embodiment 299: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R7 and R 8 is, when present, H, and R 9 is F, and the ring system is represented by Tables 142 - 282. Embodiment 300: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is F, and the ring system is represented by Tables 142 - 282. Embodiment 301: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is F, and the ring system is represented by Tables 142 - 282. Embodiment 302: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is F, and the ring system is represented by Tables 142 - 282. Embodiment 303: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9is F, and the ring system is represented by Tables 142 - 282. Embodiment 304: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is F, and the ring system is represented by Tables 142 - 282. Embodiment 305: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is F, and the ring system is represented by Tables 142 - 282. Embodiment 306: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is F, and the ring system is represented by Tables 142 - 282. Embodiment 307: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is Cl, and the ring system is represented by Tables 142 - 282. Embodiment 308: R 1 is CF3, R2 is CH3, and R 4 is H, and R 5 is H, X is O, and R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, and R 9 is Cl, and the ring system is represented by Tables 142 - 282. Embodiment 309: R 1 is CF3, and R 2 is H, and R 4 is H, and R 5 is CH3, X is O, and R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, and R 9 is Cl, and the ring system is represented by Tables 142 - 282. Embodiment 310: R 1 is CF3, and R 2 is CH3, and R 4 is H, and R 5 is CH3, X is O, and R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, and R 9 is Cl, and the ring system is represented by Tables 142 - 282. Embodiment 311: R 1 is CF3, and R 2 is H, and R 4 is H, and R 5 is H, X is S, and R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, and R 9 is Cl, and the ring system is represented by Tables 142 - 282. Embodiment 312: R 1 is CF3, and R 2 is CH3, and R 4 is H, and R 5 is H, X is S, and RW is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is Cl, and the ring system is represented by Tables 142 - 282. Embodiment 313: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is Cl, and the ring system is represented by Tables 142 - 282. Embodiment 314: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is Cl, and the ring system is represented by Tables 142 - 282. Embodiment 315: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is Br, and the ring system is represented by Tables 142 - 282. Embodiment 316: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8is, when present, H, R 9 is Br, and the ring system is represented by Tables 142 - 282. Embodiment 317: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is Br, and the ring system is represented by Tables 142 - 282. Embodiment 318: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is Br, and the ring system is represented by Tables 142 - 282. Embodiment 319: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is Br, and the ring system is represented by Tables 142 - 282. Embodiment 320: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is Br, and the ring system is represented by Tables 142 - 282. Embodiment 321: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, R 9 is Br, and the ring system is represented by Tables 142 - 282. Embodiment 322: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, R 9 is Br, and the ring system is represented by Tables 142 - 282. Embodiment 323: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, R 9 is 1 - cyanocyclopropyl, and the ring system is represented by Tables 142 - 282. Embodiment 324: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, R 9 is 1 - cyanocyclopropyl, and the ring system is represented by Tables 142 - 282. Embodiment 325: R 1 is CF3, R 2is H, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is 1 - cyanocyclopropyl, and the ring system is represented by Tables 142 - 282. Embodiment 326: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is 1 - cyanocyclopropyl, and the ring system is represented by Tables 142 - 282. Embodiment 327: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is 1 - cyanocyclopropyl, and the ring system is represented by Tables 142 - 282. Embodiment 328: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is 1 - cyanocyclopropyl, and the ring system is represented by Tables 142 - 282. Embodiment 329: R 1 is CF3, R 2 is H, R 4 is H, R5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is 1 - cyanocyclopropyl, and the ring system is represented by Tables 142 - 282. Embodiment 330: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is 1 - cyanocyclopropyl, and the ring system is represented by Tables 142 - 282. Embodiment 331: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is 1 - cyanoisopropyl, and the ring system is represented by Tables 142 - 282. Embodiment 332: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is 1 - cyanoisopropyl, and the ring system is represented by Tables 142 - 282. Embodiment 333: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is O, RW is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, and R 9 is 1 - cyanoisopropyl, and the ring system is represented by Tables 142 - 282. Embodiment 334: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, and R 9 is 1 - cyanoisopropyl, and the ring system is represented by Tables 142 - 282. Embodiment 335: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, and R 9 is 1 - cyanoisopropyl, and the ring system is represented by Tables 142 - 282. Embodiment 336: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, and R 9 is 1 - cyanoisopropyl, and the ring system is represented by Tables 142 - 282. Embodiment 337: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, and R7 and R 8 is, when present, H, and R 9 is 1 - cyanoisopropyl, and the ring system is represented by Tables 142 - 282. Embodiment 338: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is 1 - cyanoisopropyl, and the ring system is represented by Tables 142 - 282. Embodiment 339: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is CH2CH3, and the ring system is represented by Tables 142 - 282. Embodiment 340: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is CH2CH3, and the ring system is represented by Tables 142 - 282. Embodiment 341: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R9 is CH2CH3, and the ring system is represented by Tables 142 - 282. Embodiment 342: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is CH2CH3, and the ring system is represented by Tables 142 - 282. Embodiment 343: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is CH2CH3, and the ring system is represented by Tables 142 - 282. Embodiment 344: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is CH2CH3, and the ring system is represented by Tables 142 - 282. Embodiment 345: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is CH2CH3, and the ring system is represented by Tables 142 - 282. Embodiment 346: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is CH2CH3, and the ring system is represented by Tables 142 - 282. Embodiment 347: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is cPr, and the ring system is represented by Tables 142 - 282. Embodiment 348: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is cPr, and the ring system is represented by Tables 142 - 282. Embodiment 349: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is cPr, and the ring system is represented by Tables 142 - 282. Embodiment 350: R 1 is CF3, R 2is CH3, and R 4 is H, and R 5 is CH3, X is O, and R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, and R 9 is cPr, and the ring system is represented by Tables 142 - 282. Embodiment 351: R 1 is CF3, and R 2 is H, and R 4 is H, and R 5 is H, X is S, and R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, and R 9 is cPr, and the ring system is represented by Tables 142 - 282. Embodiment 352: R 1 is CF3, and R 2 is CH3, and R 4 is H, and R 5 is H, X is S, and R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, and R 9 is cPr, and the ring system is represented by Tables 142 - 282. Embodiment 353: R 1 is CF3, and R 2 is H, and R 4 is H, and R 5 is CH3, X is S, and R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, and R 9 is cPr, and the ring system is represented by Tables 142 - 282. Embodiment 354: R 1 is CF3, and R 2 is CH3, and R 4 is H, and R 5 is CH3, X is S, and RW is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, R 9 is cPr, and the ring system is represented by Tables 142 - 282. Embodiment 355: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, R 9 is benzyl, and the ring system is represented by Tables 142 - 282. Embodiment 356: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, R 9 is benzyl, and the ring system is represented by Tables 142 - 282. Embodiment 357: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, R 9 is benzyl, and the ring system is represented by Tables 142 - 282. Embodiment 358: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8is, when present, H, R 9 is benzyl, and the ring system is represented by Tables 142 - 282. Embodiment 359: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is benzyl, and the ring system is represented by Tables 142 - 282. Embodiment 360: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is benzyl, and the ring system is represented by Tables 142 - 282. Embodiment 361: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is benzyl, and the ring system is represented by Tables 142 - 282. Embodiment 362: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is benzyl, and the ring system is represented by Tables 142 - 282. Embodiment 363: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is cyclopropylmethyl, and the ring system is represented by Tables 142 - 282. Embodiment 364: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is cyclopropylmethyl, and the ring system is represented by Tables 142 - 282. Embodiment 365: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is cyclopropylmethyl, and the ring system is represented by Tables 142 - 282. Embodiment 366: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is cyclopropylmethyl, and the ring system is represented by Tables 142 - 282. Embodiment 367: R 1is CF3, R 2 is H, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is cyclopropylmethyl, and the ring system is represented by Tables 142 - 282. Embodiment 368: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is cyclopropylmethyl, and the ring system is represented by Tables 142 - 282. Embodiment 369: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is cyclopropylmethyl, and the ring system is represented by Tables 142 - 282. Embodiment 370: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is cyclopropylmethyl, and the ring system is represented by Tables 142 - 282. Embodiment 371: R 1 is CF3, R 2 is H, R4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is 2-propynyl, and the ring system is represented by Tables 142 - 282. Embodiment 372: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is 2-propynyl, and the ring system is represented by Tables 142 - 282. Embodiment 373: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is 2-propynyl, and the ring system is represented by Tables 142 - 282. Embodiment 374: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is 2-propynyl, and the ring system is represented by Tables 142 - 282. Embodiment 375: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is S, RW is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, R 9 is 2-propynyl, and the ring system is represented by Tables 142 - 282. Embodiment 376: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, R 9 is 2-propynyl, and the ring system is represented by Tables 142 - 282. Embodiment 377: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, R 9 is 2-propynyl, and the ring system is represented by Tables 142 - 282. Embodiment 378: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , if present, is H, R 9 is 2-propynyl, and the ring system is represented by Tables 142 - 282. Embodiment 379: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R8 is, when present, H, R 9 is isobutyl, and the ring system is represented by Tables 142 - 282. Embodiment 380: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is isobutyl, and the ring system is represented by Tables 142 - 282. Embodiment 381: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is isobutyl, and the ring system is represented by Tables 142 - 282. Embodiment 382: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is isobutyl, and the ring system is represented by Tables 142 - 282. Embodiment 383: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9is isobutyl, and the ring system is represented by Tables 142 to 282. Embodiment 384: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is isobutyl, and the ring system is represented by Tables 142 to 282. Embodiment 385: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is isobutyl, and the ring system is represented by Tables 142 to 282. Embodiment 386: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is isobutyl, and the ring system is represented by Tables 142 to 282. Embodiment 387: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is cyclohexylmethyl, and the ring system is represented by Tables 142 to 282. Embodiment 388: R 1 is CF3, and R 2 is CH3, and R 4 is H, and R 5 is H, X is O, and R W is CH2CH3, the exponent m is 2, and R 7 and R 8 are, when present, H, and R 9 is cyclohexylmethyl, and the ring system is represented by Tables 142 to 282. Embodiment 389: R 1 is CF3, and R 2 is H, and R 4 is H, and R 5 is CH3, X is O, and R W is CH2CH3, the exponent m is 2, and R 7 and R 8 are, when present, H, and R 9 is cyclohexylmethyl, and the ring system is represented by Tables 142 to 282. Embodiment 390: R 1 is CF3, and R 2 is CH3, and R 4 is H, and R 5 is CH3, X is O, and R W is CH2CH3, the exponent m is 2, and R 7 and R 8 are, when present, H, and R 9 is cyclohexylmethyl, and the ring system is represented by Tables 142 to 282. Embodiment 391: R 1 is CF3, and R 2 is H, and R 4 is H, and R 5 is H, X is S, and R W is CH2CH3, the exponent m is 2, and R 7 and R 8 are, when present, H, and R 9 is cyclohexylmethyl, and the ring system is represented by Tables 142 to 282. Embodiment 392: R 1 is CF3, and R2 is CH3, and R 4 is H, and R 5 is H, X is S, and R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, and R 9 is cyclohexylmethyl, and the ring system is represented by Tables 142 - 282. Embodiment 393: R 1 is CF3, and R 2 is H, and R 4 is H, and R 5 is CH3, X is S, and R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, and R 9 is cyclohexylmethyl, and the ring system is represented by Tables 142 - 282. Embodiment 394: R 1 is CF3, and R 2 is CH3, and R 4 is H, and R 5 is CH3, X is S, and R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, and R 9 is cyclohexylmethyl, and the ring system is represented by Tables 142 - 282. Embodiment 395: R 1 is CF3, and R 2 is H, and R 4 is H, and R 5 is H, X is O, and R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, and R 9 is 2 - propenyl, and the ring system is represented by Tables 142 - 282. Embodiment 396: R 1 is CF3, and R 2 is CH3, and R 4is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is 2-propenyl, and the ring system is represented by Tables 142 to 282. Embodiment 397: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is 2-propenyl, and the ring system is represented by Tables 142 to 282. Embodiment 398: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is 2-propenyl, and the ring system is represented by Tables 142 to 282. Embodiment 399: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is 2-propenyl, and the ring system is represented by Tables 142 to 282. Embodiment 400: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is S, R Wis CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, and R 9 is 2-propenyl, and the ring system is represented by Tables 142 to 282. Embodiment 401: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, and R 9 is 2-propenyl, and the ring system is represented by Tables 142 to 282. Embodiment 402: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, and R 9 is 2-propenyl, and the ring system is represented by Tables 142 to 282. Embodiment 403: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, and R 9 is CH2CF3, and the ring system is represented by Tables 142 to 282. Embodiment 404: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, and R 7 and R 8is, when present, H, and R 9 is CH2CF3, and the ring system is represented by Tables 142 - 282. Embodiment 405: R 1 is CF3, and R 2 is H, and R 4 is H, and R 5 is CH3, X is O, and R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, and R 9 is CH2CF3, and the ring system is represented by Tables 142 - 282. Embodiment 406: R 1 is CF3, and R 2 is CH3, and R 4 is H, and R 5 is CH3, X is O, and R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, and R 9 is CH2CF3, and the ring system is represented by Tables 142 - 282. Embodiment 407: R 1 is CF3, and R 2 is H, and R 4 is H, and R 5 is H, X is S, and R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, and R 9 is CH2CF3, and the ring system is represented by Tables 142 - 282. Embodiment 408: R 1 is CF3, and R 2 is CH3, and R 4 is H, and R 5 is H, X is S, and R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is, when present, H, and R 9is CH2CF3, and the ring system is represented by Tables 142 to 282. Embodiment 409: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is CH2CF3, and the ring system is represented by Tables 142 to 282. Embodiment 410: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is CH2CF3, and the ring system is represented by Tables 142 to 282. Embodiment 411: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is CH2CH2OCH3, and the ring system is represented by Tables 142 to 282. Embodiment 412: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is CH2CH2OCH3, and the ring system is represented by Tables 142 to 282. Embodiment 413: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, R 9 is CH2CH2OCH3, and the ring system is represented by Tables 142 - 282. Embodiment 414: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, R 9 is CH2CH2OCH3, and the ring system is represented by Tables 142 - 282. Embodiment 415: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, R 9 is CH2CH2OCH3, and the ring system is represented by Tables 142 - 282. Embodiment 416: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, R 9 is CH2CH2OCH3, and the ring system is represented by Tables 142 - 282. Embodiment 417: R 1 is CF3, R2 is H, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is CH2CH2OCH3, and the ring system is represented by Tables 142 - 282. Embodiment 418: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is CH2CH2OCH3, and the ring system is represented by Tables 142 - 282. Embodiment 419: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is cyclobutylmethyl, and the ring system is represented by Tables 142 - 282. Embodiment 420: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is cyclobutylmethyl, and the ring system is represented by Tables 142 - 282. Embodiment 421: R 1 is CF3, R 2 is H, R 4 is H, R5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is cyclobutylmethyl, and the ring system is represented by Tables 142 - 282. Embodiment 422: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is cyclobutylmethyl, and the ring system is represented by Tables 142 - 282. Embodiment 423: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is cyclobutylmethyl, and the ring system is represented by Tables 142 - 282. Embodiment 424: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is cyclobutylmethyl, and the ring system is represented by Tables 142 - 282. Embodiment 425: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is S, R Wis CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is cyclobutylmethyl, and the ring system is represented by Tables 142 - 282. Embodiment 426: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is cyclobutylmethyl, and the ring system is represented by Tables 142 - 282. Embodiment 427: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is H, and the ring system is represented by Tables 142 - 282. Embodiment 428: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, R 9 is H, and the ring system is represented by Tables 142 - 282. Embodiment 429: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8is, when present, H, R 9 is H, and the ring system is represented by Tables 142 - 282. Embodiment 430: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is CH3, X is O, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is H, and the ring system is represented by Tables 142 - 282. Embodiment 431: R 1 is CF3, R 2 is H, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is H, and the ring system is represented by Tables 142 - 282. Embodiment 432: R 1 is CF3, R 2 is CH3, R 4 is H, R 5 is H, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is H, and the ring system is represented by Tables 142 - 282. Embodiment 433: R 1 is CF3, R 2 is H, R 4 is H, R 5 is CH3, X is S, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, R 9 is H, and the ring system is represented by Tables 142 - 282. Embodiment 434: R 1 is CF3, and R 2 is CH3, and R 4 is H, and R 5 is CH3, X is S, and R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is H, if present, and R 9 is H, and the ring system is represented by Tables 142 to 282. Embodiment 435: R 1 is CF3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is H, if present, the ring system is represented by Table 283, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 to A480 of Table A. Embodiment 436: R 1 is CF3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is H, if present, the ring system is represented by Table 284, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 to A480 of Table A. Embodiment 437: R 1 is CF3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is H, if present, the ring system is represented by Table 285, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 to A480 of Table A. Embodiment 438: R 1 is CF3; R W is CH2CH3, the exponent m is 2, and R 7 and R 8 is H, if present, the ring system is represented by Table 286, and R2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 439: R 1 is CF3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 and R, if present, are H, the ring system is represented by Table 287, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 440: R 1 is CF3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 and R, if present, are H, the ring system is represented by Table 288, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 441: R 1 is CF3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 and R, if present, are H, the ring system is represented by Table 289, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 442: R 1 is CF3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 and R, if present, are H, the ring system is represented by Table 290, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 443: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R7 and R 8 is, when present, H, the ring system is represented by Table 291, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 444: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 292, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 445: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 293, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 446: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 294, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 447: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 295, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 448: R1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 296, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 449: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 297, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 450: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 298, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 451: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 299, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 452: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 300, and R 2 , R 3 , X and R9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 453: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 301, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 454: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 302, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 455: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 303, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 456: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 304, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 457: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8is, when present, H, the ring system is represented by Table 305, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 458: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 306, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 459: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 307, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 460: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 308, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 461: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 309, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 462: R 1 is CF3, RW is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 310, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 463: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 311, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 464: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 312, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 465: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 313, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 466: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 314, and R 2 , R 3 , X and R 9has the meaning defined in rows A1 - A480 of Table A. Embodiment 467: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 315, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 468: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 316, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 469: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 317, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 470: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 318, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 471: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8is, when present, H, the ring system is represented by Table 319, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 472: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 320, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 473: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 321, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 474: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 322, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 475: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 323, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 476: R 1 is CF3, RW is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 324, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 477: R 1 is CF3, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 325, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 478: R 1 is CF3, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 326, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 479: R 1 is CF3, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 327, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 480: R 1 is CF3, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 328, and R 2 , R 3 , X and R 9has the meaning defined in rows A1 - A480 of Table A. Embodiment 481: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 when present, is H, the ring system is represented by Table 329, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 482: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 when present, is H, the ring system is represented by Table 330, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 483: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 when present, is H, the ring system is represented by Table 331, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 484: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 when present, is H, the ring system is represented by Table 332, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 485: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8is, when present, H, the ring system is represented by Table 333, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 486: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 334, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 487: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 335, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 488: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 336, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 489: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 338, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 490: R 1 is CF3, RW is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 339, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 491: R 1 is CF3, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 340, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 492: R 1 is CF3, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 341, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 493: R 1 is CF3, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 342, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 494: R 1 is CF3, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 343, and R 2 , R 3 , X and R 9has the meaning defined in rows A1 - A480 of Table A. Embodiment 495: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 344, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 496: R 1 is CF3; R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 345, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 497: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 346, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 498: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 347, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 499: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8is, when present, H, the ring system is represented by Table 348, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 500: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 349, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 501: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 350, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 502: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 351, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 503: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 352, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 504: R 1 is CF3, RW is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 353, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 505: R 1 is CF3, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 354, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 506: R 1 is CF3, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 355, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 507: R 1 is CF3, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 356, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 508: R 1 is CF3, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 357, and R 2 , R 3 , X and R 9has the meaning defined in rows A1 - A480 of Table A. Embodiment 509: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 358, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 510: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 359, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 511: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 360, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 512: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 361, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 513: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8is, when present, H, the ring system is represented by Table 362, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 514: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 363, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 515: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 364, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 516: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 365, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 517: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 366, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 518: R 1 is CF3, RW is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 367, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 519: R 1 is CF3, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 368, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 520: R 1 is CF3, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 369, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 521: R 1 is CF3, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 370, and R 2 , R 3 , X and R 9 has the meanings defined in rows A1 - A480 of Table A. Embodiment 522: R 1 is CF3, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 371, and R 2 , R 3 , X and R 9has the meaning defined in rows A1 - A480 of Table A. Embodiment 523: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 372, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 524: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 373, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 525: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 374, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 526: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 375, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 527: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8is, when present, H, the ring system is represented by Table 376, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 528: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 377, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 529: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 378, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 530: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 379, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 531: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 380, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 532: R 1 is CF3, RW is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 381, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 533: R 1 is CF3, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 382, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 534: R 1 is CF3, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 383, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 535: R 1 is CF3, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 384, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 536: R 1 is CF3, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , if present, is H, the ring system is represented by Table 385, and R 2 , R 3 , X and R 9has the meaning defined in rows A1 - A480 of Table A. Embodiment 537: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 386, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 538: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 387, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 539: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 388, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 540: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 , when present, is H, the ring system is represented by Table 389, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 541: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8is, when present, H, the ring system is represented by Table 390, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 542: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 391, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 543: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 392, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 544: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 393, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 545: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 394, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 546: R 1 is CF3, RW is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 395, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 547: R 1 is CF3, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 396, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 548: R 1 is CF3, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 397, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 549: R 1 is CF3, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 398, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 550: R 1 is CF3, R W is CH2CH3, the exponent m is 2, and R 7 and R 8 , when present, is H, the ring system is represented by Table 399, and R 2 , R 3 , X and R 9has the meaning defined in rows A1 - A480 of Table A. Embodiment 551: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 400, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 552: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 401, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 553: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 402, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 554: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 is, when present, H, the ring system is represented by Table 403, and R 2 , R 3 , X and R 9 has the meaning defined in rows A1 - A480 of Table A. Embodiment 555: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8is, when present, H, the ring system is represented by Table 404, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 556: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 405, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 557: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 406, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 558: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ring system is represented by Table 407, and R 2 , R 3 , X and R 9 have the meanings defined in rows A1 - A480 of Table A. Embodiment 559: R 1 is CF3, R W is CH2CH3, the exponent m is 2, R 7 and R 8 are, when present, H, the ri...

Claims

1. Formula (I) 【Chemical Formula 1】 (In the formula,[[]] The circle within the ring represents that the ring is completely unsaturated; Y is C=X, and X is O; P is N(R 3 ); Q is C(R 6 ); R 1 is unsubstituted or halogenated C 1 -C 6 -alkyl; R3 is C 1 -C 6 -alkyl, C 2 -C 6 -alkenyl, C 2 -C 6 -alkynyl, C 3 -C 6 -cycloalkyl, or C 3 -C 6 -cycloalkyl-C 1 -C 4 -alkyl (these are unsubstituted or halogenated); R 2 , R 6 are H; D is a fused bicyclic ring of the following formula, 【Chemical Formula 2】 The "&" symbol means connection to the remainder of formula (I), and the dotted circle in the 5-membered ring means that the 5-membered ring is completely unsaturated; A is N; E and J are independently C or N, and at least one of the variable elements selected from E and J is C; G is a 5- or 6-membered saturated, partially unsaturated or completely unsaturated heterocyclic ring, which heterocyclic ring contains atoms E and J as ring members and is unsubstituted or substituted with one or more of the same or different substituents R 9 and, in addition to those that may exist as ring members E and J, does not contain heteroatoms; Each R 9 is, independently, H, halogen; C which is unsubstituted or substituted with one or more identical or different substituents RG 1 -C 6 -alkyl; Each R G is, independently, halogen, CN, NC; unsubstituted C 1 -C 6 -alkyl; Each R W is unsubstituted or substituted with halogen C 1 -C 6 -alkyl; m is 2) of the compounds, and their agriculturally acceptable salts.

2. R 1 is unsubstituted or halogenated C 1 -C 3 -alkyl; R 2 is H, The compound of formula (I) according to claim 1.

3. Formula (I.A) 【Chemical Formula 3】 (wherein all variable elements have the meanings defined for formula (I)) The compound of formula (I) according to claim 1 or 2, which is a compound of.

4. R 3 is C 1 -C 4 -alkyl, C 2 -C 4 alkenyl, C 2 -C 4 alkynyl, C 3 -C 6 cycloalkyl, C 3 -C 6 cycloalkyl-C 1 -C 2-alkyl (these groups are unsubstituted or halogenated); R 6 is H, A compound of formula (I-A) according to claim 3.

5. The variable element D represents a fused bicyclic ring of the following formula (D1), (D3), or (D51), 【Chemical formula 4】 The exponent z is 0, 1, 2, 3, or 4 for (D1), (D3), (D51), and the other variable elements are as defined for formula (I), and the "&" symbol means connection to the remainder of formula (I). A compound of formula (I) according to any one of claims 1 to 4.

6. Each R 9 is independently H, halogen; and C which is unsubstituted or halogenated 1 -C 3 -alkyl selected from A compound of formula (I) according to any one of claims 1 to 5.

7. R W is C 1 -C 3 -alkyl or C 1 -C 3 -haloalkyl, m is 2, A compound of formula (I) according to any one of claims 1 to 6.

8. A pesticidal mixture comprising a compound of formula (I) according to any one of claims 1 to 7 or an agriculturally acceptable salt thereof, and a further pesticidal ingredient.

9. Use of a compound of formula (I) according to any one of claims 1 to 7 as an agricultural pesticidal agent.

10. A method for controlling or preventing invertebrate pests, which comprises contacting the pest or its food supply source, habitat or breeding ground with a pesticidally effective amount of at least one compound of formula (I) according to any one of claims 1 to 7, or the mixture according to claim 8 (however, excluding methods for treating humans).

11. A method for protecting a growing plant from attack or infestation by invertebrate pests, which comprises contacting the plant, or the soil or water in which the plant is growing, with a pesticidally effective amount of at least one compound of formula (I) according to any one of claims 1 to 7, or the mixture according to claim 8.

12. Seeds containing a compound of formula (I) according to any one of claims 1 to 7, or the mixture according to claim 8, in an amount of 0.1 g to 10 kg per 100 kg of seeds.

13. Use of a compound of formula (I) according to any one of claims 1 to 7, or the mixture according to claim 8, for protecting a growing plant from attack or infestation by invertebrate pests.

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