Cosmetic composition containing sucrose ester and solvent

Abstract

The present invention relates to a cosmetic composition comprising: (a) one or more esters of sucrose and fatty acids, wherein the fatty acids are selected from those having from about 12 to about 24 carbon atoms, and the sucrose esters are selected from the group consisting of mono-esters, di-esters, triesters, tetra-esters, and mixtures thereof; and (b) one or more solvents having a viscosity of from about 23 to about 31.5 (J / cm). 3 ) 1 / 2 Hildebrand solubility parameters of about 4.5 to about 10.5 (J / cm 3 ) 1 / 2 and one or more solvents selected from those having a polar component with a Hansen solubility parameter of 0.05 to 0.05. The cosmetic composition of the present invention dissolves sucrose esters in the cosmetic composition even when the sucrose esters are contained at higher levels in the composition and / or when the sucrose esters are contained in the aqueous phase of the cosmetic composition.

Description

Technical Field

[0001] The present invention relates to a cosmetic composition comprising: (a) one or more esters of sucrose and a fatty acid, wherein the fatty acid is selected from those having about 12 to about 24 carbon atoms, and the sucrose ester is selected from the group consisting of mono-esters, di-esters, tri-esters, tetra-esters, and mixtures thereof; and (b) one or more solvents having a Hildebrand solubility parameter of about 23 to about 31.5 (J / cm 3 ) 1 / 2 and a Hansen solubility parameter polar component of about 4.5 to about 10.5 (J / cm 3 ) 1 / 2 . The cosmetic composition of the present invention dissolves the sucrose ester in the cosmetic composition even when the sucrose ester is contained at a higher level in the composition and / or when the sucrose ester is contained in the aqueous phase of the cosmetic composition.

Background Art

[0002] Keratinous tissues of mammals, particularly human skin, are subject to various damages caused by both exogenous and endogenous factors. Such exogenous factors include ultraviolet rays, environmental pollution, wind, heat, infrared rays, low humidity, strong surfactants, abrasives, and the like. On the other hand, endogenous factors include aging over time and other biochemical changes within the skin. Whether exogenous or endogenous, these factors result in visible signs of skin damage. Typical skin damages in aged or damaged skin include fine wrinkles, wrinkles, hyperpigmentation, yellowing, sagging, dark circles under the eyes, puffy eyes, enlarged pores, reduced turnover rate, and abnormal flaking or peeling. Additional damages resulting from both exogenous and endogenous factors include visible necrotic skin, i.e., peeling, scaling, dryness, and roughness.

[0003] Currently, there are several personal care products available to consumers that aim to improve the health and physical appearance of keratinous tissues such as skin, hair, and nails. Most of these products are aimed at delaying, minimizing, or even eliminating skin wrinkles, stains, and other histological changes typically associated with skin aging or environmental damage to human skin. Consumers prefer products that are applied topically because they are not only effective but also safe and comfortable to use.

[0004] Various ingredients are used in such products to deliver the above benefits. One such ingredient, namely sucrose ester, has been found by the inventors to be difficult to dissolve in the product composition, especially when the sucrose ester is contained at a higher level in the product composition and / or especially when the sucrose ester is contained in the aqueous phase of the product composition. It has also been found that it may be preferable to dissolve the sucrose ester in the aqueous phase of the product composition rather than the oil phase from the perspective of providing a fresh / light feel from the composition while providing the benefits from the sucrose ester. SUMMARY OF THE INVENTION PROBLEMS TO BE SOLVED BY THE INVENTION

[0005] Based on the above, there is a need for a cosmetic composition that dissolves sucrose ester in the cosmetic composition, especially when the sucrose ester is contained at a higher level in the composition and / or especially when the sucrose ester is contained in the aqueous phase of the cosmetic composition. There may also be a need for a cosmetic composition that provides the benefits from the sucrose ester while providing a fresh / light feel from the composition. MEANS FOR SOLVING THE PROBLEMS

[0006] The present invention is a cosmetic composition comprising (a) About 0.01% to about 50% of one or more esters of sucrose and fatty acids, wherein the fatty acid is selected from those having about 12 to about 24 carbon atoms, and the sucrose ester is selected from the group consisting of mono - esters, di - esters, tri - esters, tetra - esters, and mixtures thereof, one or more esters; (b) About 0.01% to about 90% of one or more solvents, wherein the one or more solvents have a Hildebrand solubility parameter of about 23 to about 31.5 (J / cm 3 ) 1 / 2 and a Hansen solubility parameter polar component of about 4.5 to about 10.5 (J / cm 3 ) 1 / 2 and are selected from those having the above properties, one or more solvents; and the composition satisfies at least one of the following conditions: The composition has the following conditions: The weight ratio between the sucrose ester and the solvent is about 2.5:1 to 1:10, and The solvent is pentylene glycol.

[0007] Surprisingly, the cosmetic composition of the present invention can now dissolve sucrose esters in the cosmetic composition even when the sucrose esters are contained at a higher level in the composition and / or when the sucrose esters are contained in the aqueous phase of the cosmetic composition.

[0008] Without being limited to theory, in this composition, most of the sucrose esters are considered to be contained in the aqueous phase of the composition when the composition contains an aqueous carrier. Without being limited to theory, such a composition is considered to provide a light, non - sticky, and / or fresh - feeling sensory touch while providing the benefits of sucrose esters.

Embodiments for Carrying Out the Invention

[0009] References to "embodiments" and the like in this specification mean that the specific materials, features, structures, and / or characteristics described in connection with those embodiments are included in at least one embodiment, optionally in a number of embodiments, but do not mean that the described materials, features, structures, and / or characteristics are incorporated into all embodiments. Further, the materials, features, structures, and / or characteristics may be combined in any suitable manner across different embodiments, and the materials, features, structures, and / or characteristics may be excluded from or substituted for those described. Thus, the embodiments and aspects described herein may include or be combined with elements or components of other embodiments and / or aspects even if not explicitly exemplified in combination, unless otherwise specified or incompatibility is explicitly indicated.

[0010] In all embodiments, unless otherwise stated, all percentages of components are based on the weight of the cosmetic composition. Unless otherwise specified, all ratios are by weight. The number of significant digits does not represent a limitation on the quantity shown or on the accuracy of the measured value. Unless otherwise specifically stated, all quantities are understood to be modified by the word "about". Unless otherwise stated, all measurements are understood to have been made under ambient conditions of approximately 25 °C, and "ambient conditions" means conditions of about 1 atmosphere and about 50% relative humidity. All numerical ranges are inclusive and may be combined to form sub-ranges not explicitly disclosed. For example, the upper and lower range limits separated are compatible in creating further ranges.

[0011] The compositions of the present invention can include, consist essentially of, or consist of the essential and optional components described herein. As used herein, "consisting essentially of" means that a composition or component can include only additional components that do not substantially alter the basic and novel characteristics of the claimed composition or method. As used in this specification and the appended claims, the singular forms "a", "an", and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise.

[0012] Definitions "About" refers to a range equal to plus or minus 20 percent (±20%) or a lower value (e.g., 15%, less than 10%, or even less than 5%) of the recited value, and modifies a particular value.

[0013] "Applying" or "application" as used in connection with a composition means applying or spreading the composition of the present invention onto the surface of human skin, such as the epidermis.

[0014] As used herein, "derivative" means an amide, ether, ester, amino, carboxyl, acetyl, and / or alcohol derivative of a given compound.

[0015] "Effective amount" means an amount of a compound and composition sufficient to significantly induce a positive effect on keratinous tissue over the course of a treatment period. The positive effect can be an effect on health, appearance, and / or feel, including, independently or in combination, the effects disclosed herein.

[0016] "Cosmetic agent" means any substance and any of its components intended to be rubbed, poured, sprinkled, sprayed, introduced, or otherwise applied to the body of a mammal or any part thereof for the purpose of bringing about a cosmetic effect. Cosmetic agents can include substances generally recognized as safe (GRAS) by the US Food and Drug Administration, food additives, and materials used in non-cosmetic consumer products such as over-the-counter drugs.

[0017] "Cosmetic composition" means a composition containing a cosmetic agent. Examples of cosmetic compositions include color cosmetics (e.g., foundation, lipstick, concealer, and mascara), skin care compositions (e.g., moisturizers and sunscreens), personal care compositions (e.g., rinse-off and non-rinse-off body soaps and bar soaps), and hair care compositions (e.g., shampoos and conditioners).

[0018] "Skin care" means to regulate and / or improve the skin condition (e.g., the health, appearance, or texture / feel of the skin). Some non-limiting examples of improving the skin condition include improving the appearance and / or feel of the skin by providing a smooth and more uniform appearance and / or feel, increasing the thickness of one or more layers of the skin, improving the elasticity or resilience of the skin, improving the firmness of the skin, and reducing the greasy, shiny, and / or dull appearance of the skin, improving the moisture content or hydration of the skin, improving the appearance of fine lines and / or wrinkles, improving skin exfoliation or flaking, plumping the skin, improving skin barrier properties, improving the skin color, reducing the appearance of redness or skin discoloration, and / or improving the brightness, gloss, or transparency of the skin.

[0019] "Skin care active substance" means a compound or combination of compounds that, when applied to the skin, has an acute effect and / or a chronic effect on the skin or a type of cell normally found in the skin. A skin care active substance can regulate and / or improve the skin or cells related thereto (for example, improve skin elasticity, skin moisture content, skin barrier function, and / or cell metabolism).

[0020] "Skin care composition" means a composition that contains a skin care active substance and regulates and / or improves the condition of the skin.

[0021] "Synergism" and its variations mean that the effect provided by the combination of two or more materials is greater than the additive effect expected for these materials.

[0022] As used herein, "treatment period" means the length and / or frequency of time that a material or composition is applied to the target skin surface.

[0023] Sucrose ester The sucrose esters useful herein are esters of sucrose and fatty acids, and the fatty acids are selected from those having about 12 to about 24 carbon atoms, preferably about 12 to about 22 carbon atoms, more preferably about 12 to about 18 carbon atoms, and the sucrose esters are selected from the group consisting of mono-esters, di-esters, tri-esters, tetra-esters, and mixtures thereof. Preferably, the fatty acids are selected from those having a saturated alkyl group with the above number of carbon atoms.

[0024] Preferably, the sucrose ester is included in the cosmetic composition at a level of about 0.01% to about 50%, preferably about 0.1% to about 35%, more preferably about 0.5% to about 25%, still more preferably about 1% to about 20%.

[0025] Preferably, the sucrose esters useful herein contain from about 10% to about 100%, preferably from about 20% to about 100%, more preferably from about 50% to about 90% higher esters, and the higher esters are selected from the group consisting of di-esters, tri-esters, tetra-esters, and mixtures thereof.

[0026] In some cases, the sucrose ester can be a blend of two or more sucrose esters, and the two or more sucrose esters are present in a ratio of any one sucrose ester to another sucrose ester of 1:10 to 1:1 (e.g., 1:7, 1:5, 1:3, or 1:2). In some cases, the sucrose ester can be a blend of sucrose laurate and sucrose dilaurate, where sucrose laurate is present at 50 wt% to 80 wt% of the sucrose ester and sucrose dilaurate is present at 20 wt% to 45 wt% of the sucrose ester. Alternatively, the sucrose ester can be a blend of sucrose laurate, sucrose dilaurate, and sucrose trilaurate, where sucrose dilaurate is present at 35 wt% or more of the sucrose ester. An example of a sucrose ester particularly suitable for use herein is sucrose dilaurate BC10034 available from BASF.

[0027] Solvent The solvents useful herein are selected from those having a Hildebrand solubility parameter of about 23 to about 31.5, preferably about 23 to about 29 (J / cm 3 ) 1 / 2 and a Hansen solubility parameter polar component of about 4.5 to about 10.5, preferably about 5 to about 9, more preferably about 5.5 to about 8 (J / cm 3 ) 1 / 2 from the perspective of solubilizing the sucrose ester.

[0028] As long as each solvent meets the above parameters, one or a mixture of several of the above solvents can be used. Such solvents include, for example, the following materials in the following table.

[0029]

Table 1

[0030] Among these, from the perspective of the balance between the improved solubility of sucrose esters and the minimization of the potential for skin irritation, pentylene glycol is highly preferred. In one embodiment, the solvent is pentylene glycol.

[0031] The solvent is contained in the cosmetic composition at a level of about 0.01% to about 90%, preferably about 0.1% to about 50%, more preferably about 0.5% to about 30%.

[0032] In one embodiment, the weight ratio between the sucrose ester and the solvent can be from about 1:1000 to about 1000:1, preferably from about 1:100 to about 100:1, more preferably from about 10:1 to about 1:10, still more preferably from about 5:1 to 1:10, even more preferably from about 2.5:1 to about 1:10, and even more preferably from about 2.5:1 to about 1:5, from the perspective of solubilizing the sucrose ester.

[0033] In another embodiment, the weight ratio between the sucrose ester and the solvent is from about 2.5:1 to about 1:10, preferably from about 2.5:1 to about 1:5, from the perspective of solubilizing the sucrose ester.

[0034] The following is only for the purpose of reference of the Hildebrand solubility parameter and the polar component of the Hansen solubility parameter of the components often used in cosmetic compositions, and is not the solvent defined in this specification.

[0035]

Table 2

[0036] Aqueous carrier The aqueous carriers useful herein are those other than the solvents defined above. Preferably, the aqueous carrier is substantially water. Preferably, deionized water is used. Depending on the desired properties of the product, water from natural sources containing mineral cations can also be used.

[0037] In one embodiment, the aqueous carrier can be present at a level of about 50% to about 99% by weight, preferably about 60% to about 98% by weight, more preferably about 70% to about 98% by weight, still more preferably about 80% to about 95% by weight of the composition.

[0038] Cosmetic composition The cosmetic compositions herein are intended for topical application to human skin and contain sucrose esters and a solvent, and preferably further contain an aqueous carrier. The compositions herein can optionally contain one or more additional skin actives or other ingredients of the types normally included in topical cosmetic compositions.

[0039] The cosmetic compositions herein can be cosmetic compositions, pharmaceutical compositions, or cosmeceutical compositions, and can be provided in various product forms including, but not limited to, solutions, suspensions, lotions, creams, gels, toners, sticks, sprays, aerosols, ointments, cleansing liquid washes and solid bars, pastes, foams, mousses, shaving creams, wipes, strips, patches, electric patches, hydrogels, film-forming products, facial and skin masks (with and without insoluble sheets); makeup such as foundations, eyeliners, and eyeshadows. In some cases, the form of the composition can follow a particular dermatologically acceptable carrier selected. For example, the composition (and carrier) can be provided in the form of an emulsion (e.g., oil-in-water, water-in-oil, or water-in-oil-in-water) or an aqueous dispersion. Preferably, the cosmetic composition of the present invention is in the form of a water-in-oil emulsion.

[0040] Dermatologically acceptable carrier The compositions disclosed herein may include a dermatologically acceptable carrier (which may be referred to as the "carrier"). The phrase "dermatologically acceptable carrier" means that the carrier is suitable for topical application to keratinous tissues, has good aesthetic properties, is compatible with the active substances in the composition, and does not give rise to any undue concerns regarding safety or toxicity. In one embodiment, the carrier is present at a level of about 50 wt% to about 99 wt%, about 60 wt% to about 98 wt%, about 70 wt% to about 98 wt%, or alternatively about 80 wt% to about 95 wt%.

[0041] The carrier may be in a wide variety of forms. In some cases, the form and characteristics of the carrier may be determined by the solubility or dispersibility of the components (e.g., extracts, sunscreen active substances, additional components). Non-limiting examples include simple solutions (e.g., aqueous or anhydrous), dispersions, emulsions, and solid forms (e.g., gels, sticks, flowable solids, or amorphous materials). In some cases, the dermatologically acceptable carrier is in the form of an emulsion. The emulsion may have a continuous aqueous phase (e.g., oil-in-water or water-in-oil-in-water emulsion) or a continuous oil phase (e.g., water-in-oil or oil-in-water-in-oil emulsion). The oil phase of the present invention may include silicone oils, hydrocarbon oils, esters, non-silicone oils such as ethers, and mixtures thereof. The aqueous phase typically includes water and water-soluble components (e.g., water-soluble humectants, conditioning agents, antibacterial agents, wetting agents, and / or other skin care active substances). However, in some cases, the aqueous phase may include components other than water, such as water-soluble humectants, conditioning agents, antibacterial agents, wetting agents, and / or other water-soluble skin care active substances, although not limited thereto. In some cases, the non-aqueous components of the composition include wetting agents such as glycerin and / or other polyols.

[0042] In some cases, the compositions herein are in the form of an oil-in-water (“O / W”) emulsion that provides a light and non-greasy sensory feel. Suitable O / W emulsions herein can comprise a continuous aqueous phase of greater than 50% by weight of the composition, with the balance being a dispersed oil phase. The aqueous phase can contain from 1% to 99% water, based on the weight of the aqueous phase, along with any water-soluble and / or water-miscible components. In these cases, the dispersed oil phase is typically present at less than 30% by weight of the composition (e.g., 1% - 20%, 2% - 15%, 3% - 12%, 4% - 10%, or even 5% - 8%) to help avoid some of the undesirable tactile effects of the oily composition. The oil phase can include one or more volatile and / or non-volatile oils (e.g., vegetable oils, silicone oils, and / or hydrocarbon oils).

[0043] Skin conditioning agent Optionally, the compositions of the present invention can further comprise a skin conditioning agent. These agents can be selected from humectants and emollients. The amount of the skin conditioning agent can be from about 1% to about 50% by weight of the composition, preferably from about 2% to about 40% by weight, more preferably from about 5% to about 30% by weight.

[0044] A humectant is a polyhydric alcohol intended to moisturize, reduce flaking, and stimulate the removal of accumulated flakes from the skin. Typical polyhydric alcohols include polyalkylene glycols, more preferably alkylene polyols and their derivatives. Exemplary ones are propylene glycol, dipropylene glycol, polypropylene glycol, polyethylene glycol, sorbitol, hydroxypropyl sorbitol, hexylene glycol, 1,3-butylene glycol, 1,2,6-hexanetriol, ethoxylated glycerin, propoxylated glycerin, and mixtures thereof. Most preferably, the humectant is glycerin.

[0045] When the conditioning agent is an emollient, it can be selected from hydrocarbons, fatty acids, fatty alcohols, and esters.

[0046] Aliphatic alcohol The compositions herein may contain an aliphatic alcohol. The aliphatic alcohol refers to a high molecular weight linear primary alcohol having the following general structure,

[0047] [Chemical formula] wherein n = 8 - 32.

[0048] The aliphatic alcohol can be natural or synthetic, saturated or unsaturated, branched or linear. Some non-limiting examples of fatty alcohols commonly used in cosmetic compositions include capric, capryl, lauryl, myristyl, cetyl, stearyl, and behenyl alcohol. The aliphatic alcohols herein can be generically referred to by the number of carbon atoms in the molecule. For example, "C12 alcohol" refers to an alcohol having 12 carbon atoms in its chain (i.e., dodecanol).

[0049] The aliphatic alcohol can be included in the compositions herein at 0.0001 wt% - 15 wt% (e.g., 0.0002 wt% - 10 wt%, 0.001 wt% - 15 wt%, 0.025 wt% - 10 wt%, 0.05 wt% - 7 wt%, 0.05 wt% - 5 wt%, or even 0.1 wt% - 3 wt%) of the compositions herein.

[0050] Whitening agent The compositions herein may contain a whitening agent. The whitening agents useful herein refer to active ingredients that not only change the appearance of the skin but also further improve hyperpigmentation compared to before treatment. Whitening agents useful herein include ascorbic acid compounds, vitamin B3 compounds, azelaic acid, butylhydroxyanisole, gallic acid and its derivatives, hydroquinone, kojic acid, arbutin, mulberry extract, tetrahydrocurcumin, and mixtures thereof. The use of a combination of whitening agents is considered advantageous in that they can provide the benefit of whitening by different mechanisms.

[0051] When used, the composition preferably contains from about 0.1% to about 10% by weight, more preferably from about 0.2% to about 5% by weight, of a brightening agent based on the composition.

[0052] Ascorbic acid compounds are useful brightening agents, and ascorbyl glucoside is a preferred derivative of ascorbic acid compounds.

[0053] Conditioning agent The compositions herein may contain from 0.1% to 50% by weight of a conditioning agent (e.g., 0.5% to 30%, 1% to 20%, or even 2% to 15%). Adding a conditioning agent can help provide a composition with desirable tactile properties (e.g., a silk-like smooth feel upon application). Some non-limiting examples of conditioning agents include hydrocarbon oils and waxes, silicones, fatty acid derivatives, cholesterol, cholesterol derivatives, diglycerides, triglycerides, vegetable oils, vegetable oil derivatives, acetoglyceride esters, alkyl esters, alkenyl esters, lanolin, wax esters, beeswax derivatives, sterols and phospholipids, salts, isomers, and derivatives thereof, and combinations thereof. Particularly preferred examples of conditioning agents include volatile or non-volatile silicone fluids such as dimethicone copolyol, dimethylpolysiloxane, diethylpolysiloxane, mixed C1-30 alkylpolysiloxane, phenyl dimethicone, dimethiconol, dimethicone, dimethiconol, silicone crosspolymer, and combinations thereof. Dimethicone can be particularly preferred, as some consumers associate the tactile properties provided by certain dimethicone fluids with good moisturization. Other examples of silicone fluids suitable for use as conditioning agents are described in U.S. Patent No. 5,011,681.

[0054] Thickening agent In some embodiments, the compositions of the present invention may further comprise one or more thickening agents.

[0055] Non-limiting classes of thickeners include those selected from the following carboxylic acid polymers, crosslinked polyacrylate polymers, polyacrylamide polymers, polysaccharides, and gums.

[0056] When present, the composition preferably contains from about 0.01 wt% to about 5 wt%, more preferably from about 0.1 wt% to about 4 wt%, and still more preferably from about 0.1 wt% to about 3 wt% of a thickener, based on the weight of the composition.

[0057] Emulsifying agent When the composition is in the form of an emulsion, it may contain an emulsifying agent. The emulsifying agent can be nonionic, anionic, cationic, or zwitterionic. Some non-limiting examples of emulsifying agents are disclosed in U.S. Patent Nos. 3,755,560, 4,421,769, U.S. Patent Application Publication No. 2006 / 0275237, and McCutcheon’s Detergents and Emulsifiers, North American Edition, pages 317 - 324 (1986).

[0058] Suitable examples of emulsifying agents include nonionic emulsifying agents such as polysorbate 20, polysorbate 80, polyglyceryl-4 caprate, and glyceryl-25 pyrrolidone carboxylic acid isostearate. A particularly suitable example of an emulsifying agent for use in the compositions described herein is polysorbate 20.

[0059] Other optional components The compositions of the present specification may include one or more optional components known for use in topical cosmetic compositions, provided that the optional components do not modify the desired benefits of the present composition in an unacceptable manner. In some cases, it may be desirable to select cosmetic active substances that function by different biological pathways so that the active substances do not interfere with each other. If the present composition is in the form of an emulsion, the additional components should not introduce instability (e.g., syneresis) into the emulsion. For example, it may be desirable to select optional components that do not form complexes with other components in the present composition, particularly pH-sensitive components such as vitamin B3 compounds, salicylates, and peptides.

[0060] The additional components should be suitable for use in contact with human skin tissue without excessive toxicity, incompatibility, instability, allergic response, etc. If present, the optional components may be included in an amount of about 0.001 wt% to 50 wt% (e.g., 0.01 wt% to 40 wt%, 0.1 wt% to 30 wt%, 0.5 wt% to 20 wt%, or 1 wt% to 10 wt%) of the composition. Some non-limiting examples of additional components include vitamins, minerals, peptides and peptide derivatives, sugar amines, sunscreens, oil control agents, microparticles, flavonoid compounds, hair growth regulators, antioxidants and / or antioxidant precursors, preservatives, protease inhibitors, tyrosinase inhibitors, anti-inflammatory agents, humectants, keratolytic agents, skin whitening agents, sunburn preventives, sunless tanning agents, lubricants, anti-acne agents, anti-cellulite agents, chelating agents, anti-wrinkle active substances, anti-atrophy active substances, phytosterols and / or phytohormones, N-acyl amino acid compounds, antibacterial agents, and antifungal agents. Some particularly preferred examples of additional components include one or more skin care active substances selected from the group consisting of vitamin B3 compounds (e.g., niacinamide), n-acyl amino acids (e.g., undecylenoyl phenylalanine), vitamin E compounds (e.g., tocopheryl acetate), palmitoylated dipeptides (e.g., palmitoyl-lysine-threonine), palmitoylated pentapeptides (e.g., palmitoyl-lysine-threonine-threonine-lysine-serine), vitamin A compounds (e.g., retinol propionate and retinyl propionate), and combinations thereof.Other non-limiting examples of optional components and / or skin care actives that may be suitable for use herein are disclosed in U.S. Patent Application Publication Nos. 2002 / 0022040, 2003 / 0049212, 2004 / 0175347, 2006 / 0275237, 2007 / 0196344, 2008 / 0181956, 2008 / 0206373, 2010 / 0092408, 2008 / 0206373, 2010 / 0239510, 2010 / 0189669, 2010 / 0272667, 2011 / 0262025, 2011 / 0097286, 2012 / 0197016, 2012 / 0128683, 2012 / 0148515, 2012 / 0156146, and 2013 / 0022557, and U.S. Patents Nos. 5,939,082, 5,872,112, 6,492,326, 6,696,049, 6,524,598, 5,972,359, and 6,174,533.

[0061] Method of using a cosmetic composition The method of use herein includes identifying a target portion of the skin in a human in need of treatment and applying the composition to the target portion of the skin during a treatment period. The target portion of the skin may be on the skin surface of the face (such as the forehead, around the mouth, jaw, around the eye sockets, nose, and / or cheeks), or on another part of the body (e.g., hands, arms, legs, back, chest). The human in need of treatment is a human whose skin exhibits signs of oxidative stress such as fine lines, wrinkles, hyperpigmentation, uneven skin tone, and / or other visible skin characteristics typically associated with aging. In some cases, the target portion of the skin may not show visible signs of skin aging, but if it is typically the kind that develops such problems with human aging, the user may still wish to target such skin areas. In this way, the method can be used as a preventive means for delaying the onset of visible signs of skin aging.

[0062] The composition can be applied daily to the target portion of the skin and, if desired, to the surrounding skin at least once a day, twice a day, or more frequently. When applying twice a day, leave an interval of at least 1 to 12 hours between the first and second applications. The composition is typically applied in the morning and / or before bedtime at night. The treatment period can last for at least one week (e.g., about two weeks, four weeks, eight weeks, or even twelve weeks). In some cases, the treatment period will extend over several months (i.e., 3 to 12 months). In some cases, during a treatment period of at least two weeks, four weeks, eight weeks, or twelve weeks, the composition can be applied at least once a day, or even twice a day, for most days of the week (e.g., at least four days, five days, or six days per week).

[0063] The step of applying the composition can be carried out by topical application. With respect to the application of the present composition, the terms "topical", "topically", or "locally" mean that the composition is delivered to the target area (e.g., wrinkles or lines) while minimizing delivery to skin surfaces where treatment is not desired. The present composition can be applied to a skin area and gently rubbed in. The form of the composition or the dermatologically acceptable carrier should be selected to facilitate topical application. While certain embodiments herein contemplate topical application of the present composition to an area, it will be understood that the compositions herein can be applied extensively to one or more skin surfaces. In certain embodiments, the compositions herein may be used as part of a multi-step beauty method, in which the present composition may be applied before and / or after one or more other compositions.

[0064] Manufacturing method The cosmetic composition of the present invention is preferably (a) prepared by a manufacturing method comprising the step of preparing a mixture of a sucrose ester and (b) a solvent.

[0065] From the perspective of solubilizing sucrose esters, the mixture preferably contains from about 70% to about 100% by weight, more preferably from about 80% to about 100% by weight, and even more preferably from about 90% to about 100% by weight of the total of sucrose esters and the solvent.

[0066] In the mixture, the weight ratio between the sucrose ester and the solvent is preferably from about 1:1000 to about 1000:1, more preferably from about 1:100 to about 100:1, even more preferably from about 10:1 to about 1:10, still more preferably from about 5:1 to 1:5, and even more preferably from about 2.5:1 to 1:2.5 from the perspective of solubilizing sucrose esters. In another embodiment, the weight ratio between the sucrose ester and the solvent is from about 2.5:1 to about 1:10, preferably from about 2.5:1 to about 1:5 from the perspective of solubilizing sucrose esters.

[0067] The method preferably further includes a step of mixing the mixture and an aqueous carrier. The weight ratio between the aqueous carrier and the mixture is preferably from about 1000:1 to about 1:1000, more preferably from about 1:100 to about 100:1, even more preferably from about 1:10 to about 10:1, still more preferably from about 5:1 to about 1:5, and even more preferably from about 2:1 to about 1:5. The addition of the aqueous carrier to the mixture can provide improved solubility of the sucrose ester. If there is too much aqueous carrier, it may cause a reduction in transparency / translucency and / or a reduction in the solubility of the sucrose ester. If there is too little aqueous carrier, such an improvement in the solubility of the sucrose ester may not be observed.

[0068] The step of mixing the mixture with the aqueous carrier may include two sub-steps, namely, a first dilution and a second dilution. The first dilution is the dilution of the mixture with the aqueous carrier. The second dilution is the dilution of the diluted mixture obtained from the first dilution to prepare the final product formulation of the cosmetic composition. In the second dilution, the diluent can be any one contained in the cosmetic composition, including but not limited to the aqueous carrier. In the first dilution, the weight ratio between the aqueous carrier and the mixture is preferably from about 1:10 to about 10:1, more preferably from about 5:1 to about 1:5, and even more preferably from about 2:1 to about 1:5. In the second dilution for preparing the final cosmetic composition, the diluent and any other components are added in appropriate amounts up to 100% of the cosmetic composition. In the second dilution, when other components are included, for example, thickeners, wetting agents, surfactants, pigments, powders, oils are added simultaneously and subsequently.

[0069] Combination A. A cosmetic composition, (a) from about 0.01% to about 50% by weight, preferably from about 0.1% to about 35% by weight, more preferably from about 0.5% to about 25% by weight, still more preferably from about 1% to about 20% by weight of one or more esters of sucrose and fatty acids, wherein the fatty acid is selected from those having from about 12 to about 24 carbon atoms, preferably from about 12 to about 22 carbon atoms, more preferably from about 12 to about 18 carbon atoms, and the sucrose ester is selected from the group consisting of mono-esters, di-esters, tri-esters, tetra-esters, and mixtures thereof, one or more esters; (b) from about 0.01% to about 90% by weight, preferably from about 0.1% to about 50% by weight, more preferably from about 0.5% to about 30% by weight of one or more solvents, wherein the one or more solvents have a Hildebrand solubility parameter of from about 23 to about 31.5, preferably from about 23 to about 29 (J / cm 3 ) 1 / 2 and from about 4.5 to about 10.5, preferably from about 5 to about 9, more preferably from about 5.5 to about 8 (J / cm 3 ) 1 / 2One or more solvents selected from those having a polar component of the Hansen solubility parameter, The composition satisfies the following conditions: The weight ratio between the sucrose ester and the solvent is about 2.5:1 to 1:10, and The solvent is pentylene glycol, A cosmetic composition that satisfies at least one of the above. B. The mixture contains about 70% to about 100%, preferably about 80% to about 100%, more preferably about 90% to about 100% of the total of the sucrose ester and the solvent, and has the composition of the above-mentioned characteristics. C. The fatty acid is selected from those having a saturated alkyl group having about 12 to about 24 carbon atoms, and has the composition of any of the above-mentioned characteristics. D. The weight ratio between the sucrose ester and the solvent is about 1:1000 to about 1000:1, preferably about 1:100 to about 100:1, more preferably about 10:1 to about 1:10, still more preferably about 5:1 to 1:10, and even more preferably about 2.5:1 to 1:5, and has the composition of any of the above-mentioned characteristics. E. The composition further contains an aqueous carrier and has the composition of any of the above-mentioned characteristics. F. The sucrose ester contains about 10% to about 100%, preferably about 20% to about 100%, more preferably about 50% to about 90% of higher esters, and the higher esters are selected from the group consisting of di-esters, tri-esters, tetra-esters, and mixtures thereof, and has the composition of any of the above-mentioned characteristics.

Example

[0070]

Table 3

[0071]

Table 4

[0072]

Table 5

[0073] Component

[0074]

Table 6

[0075] The second dilution Examples 1 to 5 are the skin care compositions of the present invention. The second dilution Comparative Example i is a skin care composition provided as a comparative example. As shown in the above table, the composition of the present invention can dissolve sucrose esters in the skin care composition, while the comparative example cannot dissolve sucrose esters.

[0076] The dimensions and values disclosed in this specification should not be understood as being strictly limited to the exact numerical values recited. Instead, unless otherwise indicated, each such dimension is intended to mean both the recited value and the functionally equivalent range surrounding that value. For example, a dimension disclosed as "40 mm" is intended to mean "about 40 mm".

[0077] All documents cited herein, including any patents or patent applications that are cross-referenced or related, and any patent application or patent for which this application claims priority or the benefit thereof, are hereby incorporated by reference in their entirety, unless expressly excluded or limited. No citation of any document is to be construed as an admission that it is prior art with respect to any invention disclosed or claimed herein, or that it alone, or in combination with any other reference(s), teaches, suggests, or discloses any such invention. Further, if any meaning or definition of a term in this document conflicts with any meaning or definition of the same term in a document incorporated by reference, the meaning or definition given to the term in this document shall apply.

[0078] Although specific embodiments of the invention have been illustrated and described, it will be apparent to those skilled in the art that various other changes and modifications can be made without departing from the spirit and scope of the invention. Accordingly, it is intended that all such changes and modifications within the scope of the invention be covered by the appended claims.

Claims

1. A cosmetic composition comprising a sucrose ester, wherein the sucrose ester is dissolved in the continuous aqueous phase of the composition, and the composition 0.5% to 25% by weight of the composition of one or more esters of sucrose and lauric acid, 0.5% to 30% by weight of the composition of a solvent and, the sucrose ester contains 20% to 100% by weight of a higher ester based on the weight of the sucrose ester, the higher ester is selected from the group consisting of dilauric acid ester, trilauric acid ester, tetralauric acid ester, and mixtures thereof, sucrose dilaurate is present in an amount of 35% by weight or more based on the weight of the sucrose ester, the weight ratio between the sucrose ester and the solvent is 2.5:1 to 1:10, the solvent is pentylene glycol, a cosmetic composition.

2. The composition according to claim 1, further comprising an aqueous carrier.

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