Skin cosmetic composition

Abstract

To provide a skin cosmetic composition having improved stability of dl-α-tocopherol-2-L-ascorbic acid phosphoric diester and / or a salt thereof.SOLUTION: A skin cosmetic composition contains dl-α-tocopherol-2-L-ascorbic acid phosphoric diester and / or a salt thereof, two or more selected from oxyalkylene-added polymers of glycerol (where the average number of added moles of the oxyalkylene is 2-20), and water.SELECTED DRAWING: None

Description

[Technical Field]

[0001] The present invention relates to a skin cosmetic composition. [Background technology]

[0002] Conventionally, dl-α-tocopheryl 2-L-ascorbic acid phosphate diester and / or its salt have been blended into cosmetic compositions for the purpose of improving antioxidant activity and moisturizing effect, but dl-α-tocopheryl 2-L-ascorbic acid phosphate diester and / or its salt are chemically unstable and easily decompose under the influence of temperature, sunlight, etc. Patent Document 1 discloses a cosmetic composition stably blended with dl-α-tocopheryl 2-L-ascorbic acid phosphate diester and / or its salt, but there is still room for improvement in terms of stability. [Prior art documents] [Patent documents]

[0003] [Patent Document 1] Japanese Patent Application Publication No. 08-12568 Summary of the Invention [Problem to be solved by the invention]

[0004] An object of the present invention is to provide a skin cosmetic composition containing dl-α-tocopheryl 2-L-ascorbyl phosphate diester and / or a salt thereof with improved stability. [Means for solving the problem]

[0005] As a result of extensive research, the present inventors have found that the stability of dl-α-tocopherol-2-L-ascorbic acid phosphate diester and / or its salt is improved by containing two or more members selected from dl-α-tocopherol-2-L-ascorbic acid phosphate diester and / or its salt, an oxyalkylene addition polymer of glycerin (wherein the average number of moles of oxyalkylene added is 2 to 20), and water, and have completed the present invention.

[0006] That is, the present invention [1] A skin cosmetic composition containing the following component (A), the following component (B), and the following component (C): Component (A): dl-α-tocopheryl 2-L-ascorbic acid phosphate diester and / or its salt Component (B): two or more selected from oxyalkylene addition polymers of glycerin (wherein the average number of moles of oxyalkylene added is 2 to 20) Ingredient (C): Water [2] The skin cosmetic composition according to [1], wherein the component (B) comprises the following component (B1) and the following component (B2): Component (B1): An oxyalkylene addition polymer of glycerin, in which the average number of oxyalkylene moles added is 2 or more but less than 10 Component (B2): An oxyalkylene addition polymer of glycerin, in which the average number of moles of oxyalkylene added is 10 to 20 [3] The skin cosmetic composition according to [2], wherein the content of component (B1) is 2.0 to 20.0 mass% and the content of component (B2) is 2.0 to 20.0 mass%. [4] The skin cosmetic composition according to any one of [1] to [3], wherein the content of component (C) is 59.0 to 95.0% by mass. [Effects of the Invention]

[0007] The skin cosmetic composition of this embodiment has the property of improving the stability of dl-α-tocopheryl 2-L-ascorbyl phosphate diester and / or its salt. DETAILED DESCRIPTION OF THE INVENTION

[0008] The skin cosmetic composition of this embodiment contains, as essential components, two or more selected from dl-α-tocopherol-2-L-ascorbic acid phosphate diester and / or its salt, and oxyalkylene addition polymers of glycerin (wherein the average number of moles of oxyalkylene added is 2 to 20), and water. In this specification, when a numerical range is indicated using "to" it is intended to include both ends of the range.

[0009] In this specification, the above-mentioned dl-α-tocopherol-2-L-ascorbic acid phosphate diester and / or its salt may be referred to as "component (A)"; two or more selected from the above-mentioned oxyalkylene addition polymers of glycerin (wherein the average number of moles of oxyalkylene added is 2 to 20) may be referred to as "component (B)"; and the above-mentioned water may be referred to as "component (C)".

[0010] Without intending to be bound by theory, it is believed that the skin cosmetic composition of this embodiment contains two or more oxyalkylene addition polymers of glycerin (wherein the average number of moles of oxyalkylene added is 2 to 20), which strongly inhibits the formation of micelles in component (A) and improves the stability of component (A).

[0011] <Component (A): dl-α-tocopheryl 2-L-ascorbic acid phosphate diester and / or its salt> dl-α-Tocopheryl-2-L-ascorbic acid phosphate diester is a water-soluble vitamin that combines vitamin C and vitamin E via phosphoric acid.

[0012] dl-α-Tocopheryl 2-L-ascorbic acid phosphate diester may be a salt thereof. Examples of the salt of dl-α-tocopheryl 2-L-ascorbic acid phosphate diester include inorganic salts such as sodium salt, potassium salt, magnesium salt, and ammonium salt; organic amine salts such as monoethanolammonium salt, diethanolammonium salt, and triethanolammonium salt; and basic amino acid salts such as arginine salt. From the viewpoints of safety, cost, and stability, sodium salt and potassium salt are preferred, and potassium salt is more preferred.

[0013] As the component (A), a commercially available product may be used, or a product obtained by appropriate production may be used.

[0014] The content of component (A) relative to 100% by mass of the skin cosmetic composition is preferably 0.03% by mass or more, more preferably 0.05% by mass or more, even more preferably 0.10% by mass or more, even more preferably 0.12% by mass or more, and particularly preferably 0.15% by mass or more, from the viewpoint of effects such as rough skin prevention, anti-dandruff, antibacterial, antioxidant, hair growth, hair care, blood flow promotion, moisturizing, etc. Furthermore, the content of component (A) relative to 100% by mass of the skin cosmetic composition is preferably 1.0% by mass or less, more preferably 0.8% by mass or less, even more preferably 0.5% by mass or less, and particularly preferably 0.4% by mass or less, from the viewpoint of formulation stability.

[0015] <Component (B): Two or more selected from oxyalkylene addition polymers of glycerin (wherein the average number of moles of oxyalkylene added is 2 to 20)> The skin cosmetic composition according to this embodiment can improve the stability of component (A) by containing two or more types of oxyalkylene addition polymers of glycerin (wherein the average number of moles of oxyalkylene added is 2 to 20).

[0016] In this embodiment, examples of the oxyalkylene addition polymer of glycerin include an oxyalkylene addition polymer of monoglycerin (polyoxyalkylene monoglyceryl ether) and an oxyalkylene addition polymer of polyglycerin (polyoxyalkylene polyglyceryl ether). That is, the glycerin constituting the oxyalkylene addition polymer of glycerin may be a polyglycerin in which two or more glycerins are polymerized.

[0017] Component (B) preferably contains at least one oxyalkylene addition polymer of polyglycerin, more preferably contains one or more oxyalkylene addition polymer of diglycerin (polyoxyalkylene diglyceryl ether), and even more preferably contains two or more.

[0018] The degree of polymerization of polyglycerol is not particularly limited, but is preferably 2 to 10, more preferably 2 to 5, and even more preferably 2.

[0019] The content of the oxyalkylene addition polymer of polyglycerin in component (B) is preferably 10% by mass or more, more preferably 30% by mass or more, and even more preferably 50% by mass or more. There is no particular upper limit to the content of the oxyalkylene addition polymer of polyglycerin, and it can be 100% by mass.

[0020] The average number of moles of oxyalkylene added in component (B) is 2 or more, preferably 3 or more, more preferably 4 or more, even more preferably 5 or more, and even more preferably 6 or more. The average number of moles of oxyalkylene added in component (B) is 20 or less, more preferably 18 or less, and even more preferably 16 or less.

[0021] Component (B) preferably contains an oxyalkylene addition polymer of glycerin having an average number of oxyalkylene molar additions of 2 or more but less than 10 (hereinafter sometimes referred to as "component (B1)") and an oxyalkylene addition polymer of glycerin having an average number of oxyalkylene molar additions of 10 to 20 (hereinafter sometimes referred to as "component (B2)").

[0022] In another embodiment, the component (B) may contain two or more types of component (B1) and two or more types of component (B2).

[0023] The average number of moles of oxyalkylene added in component (B1) is at least 2, preferably at least 4, and more preferably at least 6. The average number of moles of oxyalkylene added in component (B1) is less than 10, and preferably 9 or less.

[0024] Examples of component (B1) include PPG-3 glyceryl, PPG-6 glyceryl, PPG-8 glyceryl, PPG-9 glyceryl, and PPG-9 diglyceryl. Among these, from the viewpoint of improving the stability of component (A), it is preferable to contain either PPG-8 glyceryl or PPG-9 diglyceryl. In addition, a preferred embodiment includes an oxyalkylene addition polymer of diglycerin as component (B1).

[0025] The average number of moles of oxyalkylene added in component (B2) is 10 or more, preferably 11 or more, and more preferably 12 or more. The average number of moles of oxyalkylene added in component (B2) is 20 or less, more preferably 18 or less, still more preferably 17 or less, and particularly preferably 16 or less.

[0026] Component (B2) is not particularly limited, but examples thereof include PPG-10 glyceryl, PPG-16 glyceryl, PPG-14 polyglyceryl-2 ether, etc. Among these, from the viewpoint of improving the stability of component (A), component (B2) preferably contains an oxyalkylene addition polymer of diglycerin, and more preferably contains PPG-14 polyglyceryl-2 ether.

[0027] As component (B), commercially available products may be used, or those obtained by appropriate manufacturing may be used. Examples of commercially available products of component (B) that can be used include those sold by New Japan Chemical Co., Ltd., Sanyo Chemical Industries, Ltd., NOF Corporation, and Sakamoto Pharmaceutical Industries Co., Ltd.

[0028] The total content of component (B) relative to 100% by mass of the skin cosmetic composition is preferably 4.0% by mass or more, more preferably 5.0% by mass or more, even more preferably 7.0% by mass or more, and particularly preferably 10.0% by mass or more, from the viewpoint of the stability of component (A). Also, the content of component (B) relative to 100% by mass of the skin cosmetic composition is preferably 40.0% by mass or less, more preferably 35.0% by mass or less, even more preferably 30.0% by mass or less, and particularly preferably 25.0% by mass or less, from the viewpoint of the solubility of component (B) and the feel upon application (lightness of touch).

[0029] The total content of component (B1) (total of all components (B1) when two or more types are blended) relative to 100% by mass of the skin cosmetic composition is preferably 2.0% by mass or more, more preferably 3.0% by mass or more, even more preferably 4.0% by mass or more, and particularly preferably 5.0% by mass or more, from the viewpoint of the stability of component (A). Furthermore, from the viewpoint of the solubility of component (B1) and the feel upon application (lightness of application), it is preferably 20.0% by mass or less, more preferably 18.0% by mass or less, and even more preferably 15.0% by mass or less.

[0030] The total content of component (B2) (total of all components (B2) when two or more types are blended) relative to 100% by mass of the skin cosmetic composition is preferably 2.0% by mass or more, more preferably 3.0% by mass or more, even more preferably 4.0% by mass or more, and particularly preferably 5.0% by mass or more, from the viewpoint of the stability of component (A). Furthermore, from the viewpoints of the solubility of component (B2) and the feel upon application (lightness of application), it is preferably 20.0% by mass or less, more preferably 18.0% by mass or less, and even more preferably 15.0% by mass or less.

[0031] <Ingredient (C): Water> Examples of water used in this embodiment include pure water such as ion-exchanged water, ultrafiltered water, reverse osmosis water, and distilled water, and ultrapure water.

[0032] The water content of the topical skin preparation according to this embodiment, relative to 100% by mass, is not particularly limited, and can be the remainder excluding component (A), component (B), and other components. From the viewpoint of the solubility of component (A) and component (B), the water content is preferably 55.0% by mass or more, more preferably 59.0% by mass or more, even more preferably 65.0% by mass or more, even more preferably 70.0% by mass or more, even more preferably 75.0% by mass or more, and particularly preferably 80.0% by mass or more. In addition, the water content is preferably 95.0% by mass or less, more preferably 92.0% by mass or less, and even more preferably 89.0% by mass or less.

[0033] <Other ingredients> The topical skin preparation according to this embodiment may contain ingredients other than component (A), component (B), and component (C). Examples of other ingredients include active ingredients other than component (A), surfactants other than component (B), moisturizers such as lower alcohols and polyhydric alcohols, cooling agents, thickeners, fragrances, colorants, antioxidants, vitamins, animal and plant extracts, sequestering agents (chelating agents), pH adjusters, etc.

[0034] The active ingredient other than the above-mentioned ingredient (A) is not particularly limited, but examples thereof include dipotassium glycyrrhizinate, L-ascorbic acid 2-glucoside, tranexamic acid, and the like.

[0035] The surfactant other than component (B) is not particularly limited, but examples thereof include nonionic surfactants such as sorbitan isostearate, polyoxyalkylene hydrogenated castor oil, glycerin fatty acid esters, glycol fatty acid esters, sorbitan fatty acid esters, polyoxyalkylene sorbitan fatty acid esters, and silicone surfactants; anionic surfactants such as alkyl sulfate ester salts, polyoxyethylene alkyl ether sulfate salts, acyl N-methyl taurine salts, alkyl ether phosphate ester salts, and N-acyl amino acid salts; cationic surfactants such as alkyltrimethylammonium chloride and dialkyldimethylammonium chloride; and amphoteric surfactants such as alkyldimethylaminoacetic acid betaine and alkylamidopropyldimethylaminoacetic acid betaine.

[0036] When surfactants other than component (B) are contained, the total content relative to 100% by mass of the skin cosmetic composition is not particularly limited, but is preferably 0.01% by mass or more, more preferably 0.05% by mass or more, even more preferably 0.1% by mass or more, even more preferably 0.5% by mass or more, even more preferably 1.0% by mass or more, even more preferably 1.5% by mass or more, and particularly preferably 2.0% by mass or more. Furthermore, when surfactants are contained, the total content relative to 100% by mass of the skin cosmetic composition is preferably 10.0% by mass or less, more preferably 5.0% by mass or less.

[0037] The topical skin preparation according to this embodiment may contain a lower alcohol as a component other than components (A), (B), and (C). Examples of lower alcohols include linear or branched alcohols having 1 to 4 carbon atoms. Specific examples include ethanol and isopropanol, with ethanol being preferred.

[0038] When a lower alcohol is contained, its content relative to 100% by mass of the skin cosmetic composition is not particularly limited, and since the composition can be used on sensitive skin or skin with alcohol hypersensitivity, it does not need to contain a lower alcohol, but from the viewpoint of the feel when used, it is preferably 0.5% by mass or more, more preferably 1.0% by mass or more, even more preferably 2.0% by mass or more, even more preferably 2.5% by mass or more, even more preferably 3.0% by mass or more, and particularly preferably 5.0% by mass or more. Furthermore, when a lower alcohol is contained, its content relative to 100% by mass of the skin cosmetic composition is preferably 25.0% by mass or less, more preferably 20.0% by mass or less, and even more preferably 15.0% by mass or less, from the viewpoint of suppressing irritation and effectively exerting the effects of the present invention.

[0039] The polyhydric alcohol is not particularly limited, but examples thereof include glycerin, diglycerin, dipropylene glycol, 1,3-butanediol, 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol, and 1,2-decanediol.

[0040] The above-mentioned refreshing agents are not particularly limited, but examples thereof include 1-menthol, menthyl glyceryl ether, menthyl lactate, peppermint oil, camphor, icilin, etc. The above-mentioned antioxidants are not particularly limited, but examples thereof include tocopherol and derivatives thereof, ascorbic acid and derivatives thereof, etc.

[0041] Examples of the thickener include hydroxymethyl cellulose, hydroxypropyl methyl cellulose, and xanthan gum.

[0042] The sequestering agent (chelating agent) is not particularly limited, but examples thereof include edetic acid, edetate salts, phosphoric acid, sodium polyphosphate, etc. The pH adjuster is not particularly limited, but examples thereof include citric acid, tartaric acid, etc.

[0043] The site to which the skin cosmetic composition according to this embodiment is applied is not particularly limited, and examples include the face (for example, the forehead, around the eyes, under the eyes, cheeks, around the mouth, etc.), arms, elbows, backs of hands, fingertips, feet, knees, heels, neck, sides, back, etc.

[0044] The skin cosmetic composition according to this embodiment is used, for example, as cosmetics, quasi-drugs, pharmaceuticals, miscellaneous goods, etc. More specifically, for example, it is used as skin care cosmetics (moisturizing cosmetics, whitening cosmetics, acne care cosmetics, anti-aging cosmetics). In this specification, the "anti-aging cosmetics" refers to skin care cosmetics aimed at suppressing wrinkles and sagging.

[0045] The formulation of the skin cosmetic composition according to this embodiment can be carried out by a generally known production method. For example, a method of mixing the above components and stirring them using a known stirring device such as a disperser or a paddle mixer can be mentioned.

Examples

[0046] Hereinafter, this embodiment will be described in more detail based on examples, but this embodiment is not limited only to these examples. The blending amount is the blending amount of the active ingredient, unless otherwise specified, and is expressed as "mass%".

[0047] Each component shown in Table 1 was mixed according to a conventional method, and each skin cosmetic composition of the examples and comparative examples was prepared. For each of the obtained skin cosmetic compositions, the residual rate of dl-α-tocopherol-2-L-ascorbic acid phosphate diester potassium salt was evaluated as follows. The evaluation results are shown in Table 1.

[0048] <Residual rate of dl-α-tocopherol-2-L-ascorbic acid phosphate diester potassium salt> The obtained skin cosmetic compositions were filled to capacity into 50 mL airtight glass containers and stored at 40°C in a light-shielded, sealed container for 6 months. The content of dl-α-tocopheryl 2-L-ascorbic acid phosphate potassium salt in each skin cosmetic composition was measured before and after storage to determine the residual rate of dl-α-tocopheryl 2-L-ascorbic acid phosphate potassium salt. Residual rate (%) = (content of dl-α-tocopheryl 2-L-ascorbic acid phosphate diester potassium salt after storage) / (content of dl-α-tocopheryl 2-L-ascorbic acid phosphate diester potassium salt before storage) × 100

[0049] [Table 1]

[0050] The results in Table 1 show that the skin cosmetic composition according to this embodiment has improved stability of dl-α-tocopherol-2-L-ascorbic acid phosphate diester and / or its salt.

[0051] An example of the formulation is shown in Table 2. The blending amounts are expressed in "mass %."

[0052] [Table 2]

Claims

1. A skin cosmetic composition comprising the following components (A), (B) and (C): Component (A): dl-α-tocopherol-2-L-ascorbic acid phosphate diester and / or its salt Component (B): two or more selected from oxyalkylene addition polymers of glycerin (wherein the average number of moles of oxyalkylene added is 2 to 20) Component (C): water

2. 2. The skin cosmetic composition according to claim 1, wherein component (B) comprises the following component (B1) and the following component (B2): Component (B1): An oxyalkylene addition polymer of glycerin, in which the average number of moles of oxyalkylene added is 2 or more but less than 10 Component (B2): An oxyalkylene addition polymer of glycerin, in which the average number of moles of oxyalkylene added is 10 to 20

3. The skin cosmetic composition according to claim 2, wherein the content of component (B1) is 2.0 to 20.0 mass % and the content of component (B2) is 2.0 to 20.0 mass %.

4. The skin cosmetic composition according to any one of claims 1 to 3, wherein the content of component (C) is 59.0 to 95.0 mass%.

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