Foamy oral products

Abstract

To provide a foamy oral product that foams well, the foam lasting longer, and exhibits better liquid stability at high temperatures.SOLUTION: A liquid oral composition contains component (A): a hydrophobic active ingredient, component (B): at least one selected from anionic surfactants and ampholytic surfactants, component (C): polyoxyethylene alkyl ether, and component (D): a water-soluble polymer having a hydroxy group. A foamy oral product has a foam dispenser that stores the liquid oral composition.SELECTED DRAWING: None

Description

[Technical Field]

[0001] The present invention relates to foam oral products. [Background technology]

[0002] Foam oral products, which are produced by using a discharge container having a foam-forming mechanism to turn a liquid oral composition into foam, are expected to be applicable to a variety of uses. For example, since elderly people who require nursing care have difficulty brushing their teeth, foam toothpaste is suitable because it spreads easily in the oral cavity even with light brushing and is easily washed away with a light rinse.

[0003] Liquid oral compositions used in foam oral products are required to have good foaming properties and foam durability, as well as liquid stability that prevents the formation of precipitates during storage. The examples in Patent Document 1 show that in a liquid oral composition comprising a mixture of an oil-soluble medicinal ingredient (glycyrrhetinic acid or isopropylmethylphenol), a nonionic surfactant polyoxyethylene hydrogenated castor oil, an anionic surfactant sodium lauryl sulfate, and water, by setting the ratio of polyoxyethylene hydrogenated castor oil to sodium lauryl sulfate within a specific range, the liquid stability when stored at low temperatures (-5°C) is improved. [Prior art documents] [Patent documents]

[0004] [Patent Document 1] Japanese Patent Application Publication No. 2018-123086 Summary of the Invention [Problem to be solved by the invention]

[0005] According to the findings of the present inventors, the liquid composition described in Patent Document 1 does not have sufficient liquid stability when stored at high temperatures. An object of the present invention is to provide a foam oral product that has good foaming and foam persistence and excellent liquid stability at high temperatures. [Means for solving the problem]

[0006] The present invention has the following aspects. [1] A foam oral product comprising: a liquid oral composition containing (A) component: a hydrophobic active ingredient; (B) component: one or more selected from anionic surfactants and amphoteric surfactants; (C) component: a polyoxyethylene alkyl ether; and (D) component: a water-soluble polymer having a hydroxy group; and a foam-dispensing container for containing the liquid oral composition. [2] The foam oral product according to [1], wherein the component (A) is one or more selected from isopropylmethylphenol, vitamin E, glycyrrhetinic acid, and hinokitiol. [3] The foam oral product according to [1] or [2], wherein the component (B) is one or more selected from alkyl sulfates, acyltaurine salts, and fatty acid amidopropyl betaines. [4] The foam oral product according to any one of [1] to [3], wherein the component (C) is a polyoxyethylene alkyl ether having an alkyl group having 16 to 22 carbon atoms. [5] The foam oral product according to any one of [1] to [4], wherein the component (D) is one or more selected from hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropyl methylcellulose, and xanthan gum. [6] The foam oral product according to any one of [1] to [5], wherein C / A, which represents the mass ratio of the content of the component (C) to the content of the component (A), is 0.5 to 100. [Effects of the Invention]

[0007] According to the present invention, a foam oral product can be obtained which has good foaming and foam persistence and excellent liquid stability at high temperatures (hereinafter also referred to as high-temperature stability). DETAILED DESCRIPTION OF THE INVENTION

[0008] The foam oral product comprises a liquid oral composition containing components (A), (B), (C), and (D) described below, and a foam-dispensing container for containing the liquid oral composition. In this specification, a numerical range expressed as "to" means a numerical range that includes the numbers before and after "to" as the lower and upper limits.

[0009] <Component (A)> Component (A) is a hydrophobic active ingredient. Component (A) is poorly soluble in water, with a solubility of 1 g / 30 mL or less in water at 25°C. Component (A) contributes to the medicinal effect of the liquid oral composition. As the component (A), isopropylmethylphenol (IPMP), vitamin E, glycyrrhetinic acid, and hinokitiol are preferred. Examples of vitamin E include tocopherol, tocopherol acetate, tocopherol nicotinate, and tocopherol succinate. The component (A) may be used alone or in appropriate combination of two or more types. The content of component (A) is preferably 0.01 to 1% by mass, more preferably 0.05 to 0.5% by mass, relative to the total mass of the liquid oral composition. Within the above range, it is easy to ensure an effective amount of component (A).

[0010] <(B) component> Component (B) is one or more selected from anionic surfactants and amphoteric surfactants. Two or more types may be combined. Component (B) contributes to foaming (foamability) when the liquid oral composition is discharged from a foam-dispensing container.

[0011] The anionic surfactant serving as component (B) is preferably an anionic surfactant having a hydrocarbon group with a carbon chain length of 10 to 18 carbon atoms. Specific examples of anionic surfactants include alkyl sulfates, alkyl ether sulfates, alkyl benzene sulfonates, N-acyl amino acid salts, N-methyl taurine salts, and alkyl ether acetates. As the salt, alkali metal salts are preferred, and sodium salts are particularly preferred.

[0012] The amphoteric surfactant of component (B) is preferably an acetic acid betaine type amphoteric surfactant such as alkyl betaine or fatty acid amidopropyl betaine; or an imidazolinium betaine (alkylimidazole) type amphoteric surfactant such as alkylimidazolinium betaine or 2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine.

[0013] As component (B), alkyl sulfates, acyltaurine salts, and fatty acid amidopropyl betaines are preferred because they have moderate foaming properties and little bitterness. The alkyl sulfate is preferably sodium lauryl sulfate. The acyltaurine salt is preferably sodium lauroylmethyl taurate. As the fatty acid amidopropyl betaine, coconut oil fatty acid amidopropyl betaine and lauroyl amidopropyl betaine are preferred.

[0014] The content of component (B) is preferably 0.1 to 3% by mass, more preferably 0.2 to 2% by mass, and even more preferably 0.3 to 1% by mass, based on the total mass of the liquid oral composition. When the content of component (B) is 0.1% by mass or more, the foaming property is improved, and when it is 3% by mass or less, irritation (stinging sensation) of the oral mucosa is easily suppressed.

[0015] <(C) component> Component (C) is a polyoxyethylene alkyl ether, a so-called nonionic surfactant. Component (C) contributes to foaming (foaming ability) and inhibits foam breakage, and contributes to high-temperature stability by being less likely to precipitate even at high temperatures. Component (C) may be used alone or in combination of two or more.

[0016] Component (C) preferably has an alkyl group having 10 to 22 carbon atoms, more preferably has an alkyl group having 14 to 22 carbon atoms, even more preferably has an alkyl group having 16 to 22 carbon atoms, and particularly preferably has an alkyl group having 18 to 22 carbon atoms. The average number of moles of ethylene oxide added per mole of component (C) (hereinafter also referred to as "number of moles of EO added") is preferably 10-50, and more preferably 15-30.

[0017] The component (C) is preferably polyoxyethylene (hereinafter also referred to as "POE") lauryl ether, POE cetyl ether, POE stearyl ether, POE oleyl ether, or POE behenyl ether, more preferably POE behenyl ether, POE cetyl ether, or POE stearyl ether, and even more preferably POE behenyl ether. It is preferred that component (C) contains at least POE behenyl ether. Of the total mass of component (C), the proportion of POE behenyl ether is preferably 50 mass% or more, more preferably 60 mass% or more, even more preferably 70 mass% or more, and particularly preferably 80 mass% or more. It may even be 100 mass%.

[0018] The content of the component (C) is preferably 0.5 to 5 mass %, more preferably 1 to 3 mass %, and even more preferably 1.5 to 2.5 mass %, relative to the total mass of the liquid oral composition. When the content of component (C) is 0.5% by mass or more, the effect of improving high-temperature stability is excellent. In addition, the liquid oral composition foams well when discharged from a foam-dispensing container. When the content of component (C) is 5% by mass or less, the flavor is well-developed. In addition, when the liquid oral composition is discharged from a foam-dispensing container, there is not too much foam, making it easy to use.

[0019] <(D) component> Component (D) is a water-soluble polymer having a hydroxy group, preferably a hydroxyalkyl cellulose or a polymeric polysaccharide. Component (D) contributes to the persistence of foam. In addition, it contributes to improving rinsing properties. Good rinsing properties mean that foam is less likely to remain when rinsing the oral cavity with water. Component (D) may be used alone or in combination of two or more.

[0020] Component (D) is preferably one that provides a clear 0.1% by mass aqueous solution or swelling liquid at 20° C. Specific examples include hydroxyalkyl celluloses such as hydroxyethyl cellulose, hydroxypropyl cellulose, and hydroxypropylmethyl cellulose; and polysaccharides such as xanthan gum, guar gum, and carrageenan. Component (D) is preferably hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropylmethyl cellulose, or xanthan gum, more preferably hydroxyethyl cellulose or xanthan gum, and even more preferably hydroxyethyl cellulose.

[0021] The content of the component (D) is preferably 0.01 to 0.5% by mass, more preferably 0.02 to 0.1% by mass, relative to the total mass of the liquid oral composition. If the content of component (D) is 0.01% by mass or more, the effect of improving foam persistence is excellent, and if it is 0.5% by mass or less, the dischargeability from the foam discharge container is excellent. Specifically, regarding ejection properties, if the content of component (D) is too high, the liquid oral composition becomes highly viscous, making it difficult to eject, and the nozzle of the foam ejection container is likely to become clogged, which can cause other inconveniences.

[0022] <Mixing ratio> When component (A) is added to a liquid oral composition, it tends to be difficult to foam and the bubbles tend to break easily, but by combining it with component (C), which has the effect of inhibiting bubble breakage, good foaming and foam retention can be achieved. C / A, which represents the mass ratio of the content of the component (C) to the content of the component (A), is preferably 0.5-100, more preferably 5-50, and even more preferably 10-50. When C / A is 0.5 or more, good foaming and foam persistence are likely to be achieved, and when it is 100 or less, the medicinal effects of component (A) are likely to be fully achieved.

[0023] <Solvent> It is preferable that the liquid oral composition contain a solvent. The solvent preferably contains purified water and may further contain a lower monohydric alcohol having 2 to 4 carbon atoms. Based on the total mass of the liquid oral composition, the content of lower monohydric alcohol is preferably 5% by mass or less, more preferably 3% by mass or less, even more preferably 1% by mass or less, and particularly preferably substantially none, from the standpoints of irritation and foam performance. In this specification, "substantially free of lower monohydric alcohols" means that lower monohydric alcohols are not added alone. For example, lower monohydric alcohols derived from added ingredients, such as ethanol contained in fragrances, may be included. In this specification, if the content of lower monohydric alcohols is 0.01% by mass or less relative to the total mass of the liquid oral composition, it is considered to be substantially free of lower monohydric alcohols.

[0024] <Other optional ingredients> In addition to the above components (A) to (D) and the solvent, the liquid oral composition may contain optional components known in liquid oral compositions, as long as the effects of the present invention are not impaired. Examples of optional components include humectants, thickeners, pH adjusters, preservatives, sweeteners, flavorings, water-soluble active ingredients, and colorants.

[0025] Examples of humectants include glycerin; glycols such as propylene glycol, ethylene glycol, and polyethylene glycol; and sugar alcohols such as sorbitol, xylitol, erythritol, maltitol, and lactitol.

[0026] Examples of thickeners include anionic polymers such as sodium alginate, sodium carboxymethyl cellulose, and sodium polyacrylate.

[0027] Examples of pH adjusters include organic acids such as citric acid, malic acid, succinic acid, tartaric acid, phthalic acid, acetic acid, and fumaric acid; inorganic acids such as phosphoric acid; and water-soluble salts thereof (sodium salts, potassium salts, and ammonium salts).

[0028] Examples of preservatives include parahydroxybenzoic acid esters such as methylparaben, ethylparaben, propylparaben, and butylparaben; benzoic acid or a salt thereof such as sodium benzoate; alkyldiaminoethylglycine hydrochloride; and potassium sorbate.

[0029] Examples of sweeteners include saccharin sodium, stevioside, sucralose, and reduced palatinose.

[0030] Fragrances include natural essential oils such as peppermint oil, spearmint oil, peppermint oil, eucalyptus oil, wintergreen oil, clove oil, thyme oil, sage oil, cardamom oil, rosemary oil, marjoram oil, lemon oil, orange oil, nutmeg oil, lavender oil, and paracles oil; fragrance components contained in the above natural essential oils such as L-menthol, L-carvone, 1,8-cineole, methyl salicylate, eugenol, thymol, linalool, limonene, menthone, menthyl acetate, citral, camphor, borneol, pinene, and spilanthol; and ethyl acetate, ethyl butyrate, isoamyl acetate, hexanal, hexenal, methyl ... Examples of flavor compounds include single flavoring ingredients such as thyl anthranilate, ethyl methylphenylglycidate, benzaldehyde, vanillin, ethyl vanillin, furaneol, maltol, ethyl maltol, gamma / delta decalactone, gamma / delta decalactone, N-ethyl-p-menthane-3-carboxamide, menthyl lactate, and ethylene glycol-L-menthyl carbonate; and blended flavors such as apple, banana, strawberry, blueberry, melon, peach, pineapple, grape, muscat, wine, cherry, squash, coffee, brandy, and yogurt, which are made by combining several flavoring ingredients and natural essential oils.

[0031] Examples of water-soluble active ingredients include fluorine compounds such as sodium fluoride, sodium monofluorophosphate, and stannous fluoride; anti-inflammatory agents such as dipotassium glycyrrhizinate, ε-aminocaproic acid, allantoin, and tranexamic acid; disinfectants such as cetylpyridinium chloride and benzalkonium chloride; hypersensitivity improvers such as potassium nitrate and aluminum lactate; and stain removers such as sodium tripolyphosphate, sodium pyrophosphate, and sodium metaphosphate.

[0032] <Physical properties> The pH of the liquid oral composition at 25°C is preferably 5 to 8, and a pH adjuster in this range may be added, such as a combination of sodium dihydrogen phosphate and sodium monohydrogen phosphate, or a combination of citric acid and sodium citrate.

[0033] The viscosity of the liquid oral composition may be any viscosity that allows it to be easily dispensed from a foam dispenser. For example, the viscosity at 25°C is preferably 0.7 Pa·s or less, particularly 0.005 to 0.1 Pa·s. Within this range, good foaming (foam formation) and foam shape retention can be achieved. If the viscosity is higher than 0.7 Pa·s, good foam formation may not be achieved, and if the viscosity is too low, the foam shape retention may be poor. The viscosity in this specification refers to a value measured at 25°C using a BL type viscometer.

[0034] <Container> The foam oral product of the present invention has a foam-dispensing container that contains a liquid oral composition. The foam-dispensing container may have any structure as long as it has a foam-forming mechanism and can dispense the liquid oral composition contained therein in foam form, and any known structure may be adopted as appropriate. The foam-dispensing container is preferably a non-aerosol, non-gas, atmospheric pressure container that has a structure in which the contents are mixed with air and sprayed in foam form from a nozzle by applying pressure to the contents. Such foam-dispensing containers can be well-known squeeze-type or pump-dispenser-type containers. For example, foam-dispensing containers with the structures described in Japanese Utility Model Publication No. 7-6108, Japanese Utility Model Publication No. 7-8251, and Japanese Utility Model Publication No. 4-102666 can be used, and various commercially available products can also be used.

[0035] <How to use> With the liquid oral composition contained in the foam-dispensing container, an external force is applied to the foam-dispensing container to discharge foam, and the discharged foam is applied to the oral cavity. For example, an appropriate amount of foam is discharged onto a toothbrush for use in brushing teeth. [Example]

[0036] The present invention will be described in detail below with reference to examples, but the present invention is not limited to the following description.

[0037] <Raw materials used> [Component (A)] IPMP: Isopropylmethylphenol (Osaka Chemical Industry Co., Ltd., product name: Isopropylmethylphenol) Hinokitiol (manufactured by Takasago Chemical Co., Ltd., product name: Hinokitiol) Tocopherol acetate (vitamin E) (manufactured by DSM Nutrition Japan, product name: Tocopherol acetate) Glycyrrhetinic acid (Maruzen Pharmaceutical Co., Ltd., product name: Glycyrrhetinic acid) [(B) Component] Sodium lauryl sulfate: Sodium lauryl sulfate (manufactured by BASF, trade name: Texapon OC-P) Sodium Lauroyl Methyl Taurate: Sodium Lauroyl Methyl Taurate Coconut oil fatty acid amidopropyl betaine (manufactured by Degussa, product name: TEGO BETAINCK-OK) 2-Alkyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine (manufactured by Ipposha Oil Industries Co., Ltd., trade name: Energical C-40H) Lauroylamidopropyl betaine (manufactured by Kawaken Fine Chemicals Co., Ltd., trade name: Softazoline LPB) [(C) component] POE (30) behenyl ether: polyoxyethylene behenyl ether, EO addition mole number 30 (manufactured by Nippon Emulsion Co., Ltd., trade name: EMALEX BHA-30) POE (20) stearyl ether: Polyoxyethylene stearyl ether, EO addition mole number 20 (manufactured by Nippon Emulsion Co., Ltd., trade name: EMALEX 625) POE (15) cetyl ether: polyoxyethylene cetyl ether, EO addition mole number 15 (manufactured by Nippon Emulsion Co., Ltd., trade name: EMALEX 115) [(C') component: Comparative example] POE hydrogenated castor oil 60: Polyoxyethylene hydrogenated castor oil, EO addition mole number 60. (Nikko Chemicals Co., Ltd., product name: Nikkol HCO-60M) [(D) component] Hydroxyethyl cellulose (manufactured by Daicel Miraize Co., Ltd., product name: HEC Daicel) Hydroxypropyl methylcellulose (manufactured by Shin-Etsu Chemical Co., Ltd., trade name: METOLOSE 90SH-4000SR) Xanthan gum (manufactured by CP Kelco, product name: Monart Gum DA) [(D') component: Comparative example] CMC-Na: Carboxymethylcellulose sodium (manufactured by Daicel Miraize Co., Ltd., trade name: Daicel CMC1380) [Optional ingredients] Sodium fluoride (manufactured by Stella Chemifa Corporation, product name: Sodium fluoride) Cetylpyridinium chloride (manufactured by Fujifilm Wako Pure Chemical Industries, Ltd., product name: Cetylpyridinium chloride) Allantoin (manufactured by PermaChem Asia Co., Ltd., product name: Allantoin) Glycerin (manufactured by Sakamoto Pharmaceutical Co., Ltd., product name: 85% cosmetic glycerin) Propylene glycol (ADEKA Corporation, product name: Propylene glycol) Sorbitol (Mitsubishi Corporation Life Sciences, product name: 70% Sorbitol Solution) Xylitol (manufactured by Rocket Fleuret, product name: XYLISORB) Sodium citrate: Sodium citrate (manufactured by Komatsuya Co., Ltd., trade name: trisodium citrate) Citric acid (manufactured by Komatsuya Co., Ltd., product name: citric acid) Sodium benzoate: Sodium benzoate (manufactured by Fushimi Pharmaceutical Co., Ltd., trade name: Sodium Benzoate) Methylparaben (manufactured by Ueno Pharmaceutical Co., Ltd., trade name: methyl parahydroxybenzoate) ·Fragrance ·Water: Purified water

[0038] (Examples 1 to 20, Comparative Examples 1 to 5) According to the formulations shown in Tables 1 to 3, liquid oral compositions were prepared by a conventional method. In the following table, the numerical values ​​indicating the blending amount are the content (unit: mass%) relative to the total mass of the liquid oral composition. Unless otherwise specified, the blending amount is a pure equivalent value. Components for which the blending amount is not listed in the table are not blended. The "balance" indicating the water content means the remainder added so that the total blending amount (mass%) of all blended components contained in the liquid oral composition becomes 100 mass%. The liquid oral compositions of Examples 1 to 20 and Comparative Examples 1 to 5 all had a pH value of 5.5 to 6.5 at 25°C. The liquid oral compositions of Examples 1 to 20 also had a viscosity value of 0.005 to 0.1 Pa s at 25°C. The resulting liquid oral composition was filled into a foaming container to produce a foaming oral product. The foaming container was a non-aerosol, non-gas, atmospheric pressure container that applies pressure to the contents to mix them with air and discharge them in the form of foam from its outlet.

[0039] <Evaluation method> Each foam oral product was evaluated for foaming, foam persistence, irritation, and high-temperature stability as follows. The results are shown in Tables 1 to 3.

[0040] [Foaming] Foam was dispensed from the foam dispenser onto the toothbrush, and the uniformity of the foam immediately afterwards was visually evaluated based on the size of the bubbles, and the proportion of large, uneven bubbles was evaluated according to the following criteria. The fewer uneven parts and the more fine, uniform bubbles there were, the better the foaming. A rating of △ or higher was considered a pass. ◎: The bubbles present on the surface of the foam are uniform overall, with uneven areas of less than 10%. ○: 10% or more and less than 25% of the foam surface is uneven. △: 25% or more but less than 50% of the foam surface is uneven. ×: 50% or more of the surface of the foam is uneven.

[0041] [Foam durability and irritation] Immediately after production, the foam oral product was subjected to a usability test by five expert panelists as follows. The foam (approximately 0.2 mL) was applied to a toothbrush (Lion Corporation product name: Clinica Advantage Toothbrush, 4-row compact, regular type) and teeth were brushed for 3 minutes. The sensation of irritation during use and the state of foam remaining in the mouth at the end of brushing (foam persistence) were scored using the following criteria. The average score of the five subjects was calculated and evaluated using the following criteria. (Scoring criteria for foam persistence) 5 points: sufficient bubbles are observed. 4 points: Bubbles are observed. 3 points: Some bubbles are observed. 2 points: Almost no bubbles are observed. 1 point: No bubbles observed. (Scoring criteria for irritation sensation) 5 points: No irritation felt. 4 points: Almost no stimulation felt. 3 points: Slight irritation. 2 points: Feels quite irritated. 1 point: Very irritating. [Evaluation criteria for foam durability and irritation (above △ is considered a pass)] ◎: The average score of the 5 people is 4.5 points or higher. ○: The average score of the 5 people is 4 points or more but less than 4.5 points. △: The average score of the 5 people is 3 or more but less than 4 points. ×: The average score of the 5 people is less than 3 points.

[0042] [High temperature stability] The foam oral product immediately after production was stored in an environment of 50°C for one month, and then the liquid oral composition in the container was visually observed and evaluated according to the following criteria. ⊚: No precipitates were observed. ◯: A small amount of precipitate was observed. ×: A large amount of precipitates was observed.

[0043] [Table 1]

[0044] [Table 2]

[0045] [Table 3]

[0046] As shown in Tables 1 to 3, the foam oral products of Examples 1 to 20 had good foaming and foam persistence, and also had excellent high-temperature stability. In addition, the irritating sensation of the foam was mild and reduced. In contrast, Comparative Example 1, which did not contain component (B), was inferior in lathering and lather persistence. Comparative Example 2, which did not contain component (C), was inferior in lathering and lather persistence, and the lather was also very irritating. Comparative Example 3, which did not contain component (C) but contained component (C'), had poor high-temperature stability. Comparative Example 4, which did not contain component (D), had poor foam persistence. Comparative Example 5, which did not contain component (D) but contained component (D'), had poor foam persistence.

[0047] <Production Examples 1 to 4> According to the compositions of Formulation Examples 1 to 4 shown in Table 4, foam oral products were produced in the same manner as in Example 1.

[0048] [Table 4]

Claims

1. (A) component: a hydrophobic active ingredient; Component (B): one or more surfactants selected from anionic surfactants and amphoteric surfactants; (C) component: polyoxyethylene alkyl ether, Component (D): a water-soluble polymer selected from hydroxyalkyl cellulose and xanthan gum; The foam oral product comprises a liquid oral composition containing the above components, wherein the content of the (D) component is 0.01 to 0.5 mass %, and C / A, which represents the mass ratio of the content of the (C) component to the content of the (A) component, is 0.5 to 100, and a foam-dispensing container that contains the liquid oral composition.

2. 2. The foam oral product according to claim 1, wherein the component (A) is one or more selected from the group consisting of isopropylmethylphenol, vitamin E, glycyrrhetinic acid, and hinokitiol.

3. 3. The foam oral product according to claim 1, wherein the component (B) is at least one selected from the group consisting of alkyl sulfates, acyltaurine salts, and fatty acid amidopropyl betaines.

4. The foam oral product according to any one of claims 1 to 3, wherein the component (C) is a polyoxyethylene alkyl ether having an alkyl group having 16 to 22 carbon atoms.

5. The foam oral product according to any one of claims 1 to 4, wherein the component (D) is one or more selected from the group consisting of hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropyl methylcellulose, and xanthan gum.

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