Medical tubular body transport device

Abstract

To provide a medical tubular body transport device capable of inserting easily, a guide wire into a lumen of a tip end tip, and suppressing deviation of the guide wire inserted into a lumen of the tip end tip, and achieving preferable operation property.SOLUTION: A medical tubular body transport device for transporting into a body, a medical tubular body, comprises: an outside tube in which the medical tubular body is arranged on the lumen; an inside tube provided in the lumen of the outside tube; and a tip end tip which is fixed to a distal end of the inside tube through an adhesive material. The tip end tip has a lumen extending in a long axis direction, the lumen is communicated with the lumen of the inside tube, the part of the adhesive material extends inward, relative to the inside surface of the tip end tip.SELECTED DRAWING: Figure 1

Description

[Technical Field]

[0001] The present invention relates to a medical tubular body delivery device. [Background technology]

[0002] In recent years, minimally invasive treatment techniques have been developed for delivering and positioning medical tubular objects within the body. Examples of medical tubular objects include stents, stent grafts, occluders, injection catheters, and prosthetic valves. Among these, stents are generally used to treat various diseases caused by narrowing or occlusion of a body lumen.

[0003] The medical tubular body is delivered into the body through a body lumen using a delivery device. The delivery device has an outer tube, and is inserted into the body lumen with the medical tubular body held in the lumen of the outer tube. Once delivered to a predetermined position inside the body, the medical tubular body is released from the lumen of the outer tube and placed (deposited) at the predetermined position inside the body.

[0004] When delivering a medical tubular object into the body using a delivery device, a guidewire is first passed through a lumen in the body, and then the medical tubular object located at the distal end of the medical tubular object delivery device is advanced along the guidewire until it reaches the lesion. However, even when the guidewire is advanced in this manner, the medical tubular object delivery device may be unable to advance due to a stent previously placed in the lumen in the body, a narrowed portion of the lumen in the body, or a sharp bend in the lumen in the body, resulting in poor tracking of the guidewire.

[0005] Patent Document 1 describes a catheter (delivery device) with improved followability relative to a guidewire. The catheter described in Patent Document 1 has a tapered tip end that narrows its inner diameter. This reduces the clearance between the inner periphery of the tip end and the outer periphery of the guidewire, preventing the guidewire from becoming eccentric at the tip end of the catheter and rattling. As a result, the followability of the catheter relative to the guidewire is improved. [Prior art documents] [Patent documents]

[0006] [Patent Document 1] Japanese Patent Application Laid-Open No. 2006-149442 Summary of the Invention [Problem to be solved by the invention]

[0007] As in Patent Document 1, narrowing the inner diameter of the catheter tip improves the catheter's ability to follow the guidewire, but narrowing the inner diameter of the catheter tip makes it difficult to insert the guidewire.

[0008] The present invention was made in consideration of the above circumstances, and its purpose is to provide a medical tubular body transport device that is easy to insert a guide wire into the lumen of the distal tip, suppresses vibration of the guide wire passed through the lumen of the distal tip, and is easy to operate. [Means for solving the problem]

[0009] The present invention is as follows. [1] A medical tubular body delivery device for delivering a medical tubular body into the body, comprising: an outer tube in whose lumen the medical tubular body is disposed; an inner tube in whose lumen the outer tube is disposed; and a distal tip fixed to the distal end of the inner tube via an adhesive material, wherein the distal tip has an inner lumen extending in the longitudinal direction, the inner lumen communicating with the inner lumen of the inner tube, and a portion of the adhesive material extending inward beyond the inner surface of the distal tip. [2] The medical tubular body delivery device according to [1], wherein a portion of the adhesive material extends inward beyond the inner surface of the inner tube. [3] The medical tubular body delivery device according to [1] or [2], wherein a portion of the adhesive material extends onto a portion of the inner circumference of the distal tip. [4] A medical tubular body transport device according to any one of [1] to [3], wherein a portion of the adhesive material extends inward beyond the inner surface of the inner tube and extends onto a portion of the inner circumference of the inner tube. [5] A medical tubular body transport device according to any one of [1] to [4], wherein the void area S1 of the lumen of the distal tip in a cross section perpendicular to the longitudinal direction distal to the position where a portion of the adhesive material extends inward beyond the inner surface of the distal tip, the void area S2 of the lumen in a cross section perpendicular to the longitudinal direction at the position where a portion of the adhesive material extends inward beyond the inner surface of the distal tip, and the void area S3 of the lumen of the inner tube in a cross section perpendicular to the longitudinal direction proximal to the position where a portion of the adhesive material extends inward beyond the inner surface of the distal tip satisfy the relationship expressed by the following formula: S2 <S1≦S3 [6] The medical tubular body delivery device according to any one of [1] to [5], wherein the outside of the distal end of the inner tube is covered with the proximal end of the distal tip. [7] The medical tubular body delivery device according to any one of [1] to [5], wherein a radiopaque marker is provided at the distal end of the inner tube. [Effects of the Invention]

[0010] In the medical tubular body delivery device according to the present invention, a distal tip is fixed to the distal end of an inner tube via an adhesive material, and a portion of the adhesive material extends inward beyond the inner surface of the distal tip. Therefore, the extended adhesive material holds a guidewire passed through the lumen of the distal tip without narrowing the inner diameter of the distal tip, thereby suppressing guidewire wobble and improving operability of the medical tubular body delivery device. Furthermore, good guidewire insertion performance is maintained. Furthermore, by extending a portion of the adhesive material over a portion of the inner circumference of the distal tip, performance is improved in both suppressing guidewire wobble and ensuring smooth sliding. [Brief explanation of the drawings]

[0011] [Figure 1] FIG. 1 is a cross-sectional view showing one embodiment of a medical tubular body transport device according to the present invention. [Figure 2] FIG. 2 is a cross-sectional view showing a state in which a core material is inserted into the lumen of the inner tube. DETAILED DESCRIPTION OF THE INVENTION

[0012] The medical tubular body delivery device according to the present invention is a medical tubular body delivery device for delivering a medical tubular body into a body, and includes an outer tube in whose lumen the medical tubular body is disposed, an inner tube in the lumen of the outer tube, and a distal tip fixed to the distal end of the inner tube via an adhesive material. The distal tip has a lumen extending in the longitudinal direction and communicating with the lumen of the inner tube, and a portion of the adhesive material extends inward beyond the inner surface of the distal tip. The portion of the adhesive material extending inward beyond the inner surface of the distal tip locally reduces the lumen diameter of the distal tip. Therefore, when a guidewire is passed through the lumen of the distal tip, the guidewire is held in place by the adhesive material present in the area where the lumen diameter is locally reduced. As a result, wobble of the guidewire during sliding is suppressed without narrowing the inner diameter of the distal end of the distal tip. Therefore, according to the present invention, the insertion property of the guide wire can be maintained good, and the wobbling of the guide wire when it slides can also be suppressed.

[0013] The medical transport device according to the present invention will be described in more detail below based on the following embodiments. However, the present invention is not limited to these embodiments. Modifications and variations are possible within the scope of the above and below-described spirit and all such variations are within the technical scope of the present invention. For convenience, hatching and component symbols may be omitted in the drawings. In such cases, reference should be made to the specification and other drawings. The dimensions of various components in the drawings may differ from their actual dimensions, as they are intended to facilitate understanding of the features of the present invention. Hereinafter, the proximal side refers to the side closest to the user (operator), and the distal side refers to the side opposite the proximal side (i.e., the side to be treated). The direction from the proximal side to the distal side is referred to as the longitudinal axis direction or the distal direction.

[0014] 1 is a cross-sectional view showing one embodiment of a medical tubular body delivery device according to the present invention, showing only the distal portion of the medical tubular body delivery device. In FIG. 1, the right side of the arrow x is the proximal side, and the left side of the arrow x is the distal side.

[0015] The medical tubular body delivery device 1 comprises an outer tube 2 having a medical tubular body (not shown) disposed in its lumen, an inner tube 3 disposed in the lumen of the outer tube 2, and a distal tip 4 fixed to the distal end of the inner tube 3 via an adhesive material 5. The distal tip 4 has a lumen extending in the longitudinal axis direction x, and this lumen communicates with the lumen of the inner tube 3.

[0016] A portion of the adhesive material 5 extends inward beyond the inner surface 4a of the distal tip 4. As a result, a guidewire inserted into the lumen of the distal tip 4 is held by the adhesive material 5 extending inward beyond the inner surface 4a of the distal tip 4, thereby suppressing vibration and improving the operability of the medical tubular body delivery device 1. Furthermore, according to the present invention, the adhesive material 5 disposed at the fixing position between the inner tube 3 and the distal tip 4 extends inward beyond the inner surface 4a of the distal tip 4, so that vibration of the guidewire can be suppressed while maintaining good insertability of the guidewire without having to narrow the inner diameter of the distal end of the distal tip 4.

[0017] The adhesive material 5 only needs to extend inward beyond the inner surface 4a of the distal tip 4. The adhesive material 5 may extend over the entire inner circumference of the distal tip 4, but preferably extends over a portion of the inner circumference of the distal tip 4. By having a portion of the adhesive material 5 extend over a portion of the inner circumference of the distal tip 4, performance is improved in both suppressing guidewire wobble and ensuring slidability.

[0018] When the adhesive material 5 extends onto a portion of the inner circumference of the distal tip 4, it may extend to one location or to two or more locations, but it is preferable that it extend to two or more locations. By extending to two or more locations, vibration of the guidewire can be further suppressed.

[0019] When the adhesive material 5 extends from two or more locations on the inner circumference of the distal tip 4, the positions from which the adhesive material 5 extends may be equally or unequally spaced in the circumferential direction, but equally spaced positions are preferred, as the guidewire can be held at the center of its axis more easily.

[0020] For example, an organic adhesive can be used as the adhesive material 5, and specifically, a resin adhesive such as a urethane resin adhesive, an epoxy resin adhesive, an olefin adhesive, a cyanoacrylate adhesive, or a silicone adhesive can be used. Among these, it is preferable to use a urethane resin adhesive.

[0021] The distal tip 4 extends in the distal-proximal direction and has an inner lumen. The distal tip 4 makes it easier for the medical tubular body delivery device 1 to pass through a narrowed portion of a lumen in the body. The outer shape of the cross section of the distal tip 4 perpendicular to the longitudinal axis direction x may be, for example, a circle, a C-shape, an ellipse, a polygon, or the like. The maximum inner diameter of the distal tip 4 is preferably larger than the outer diameter of the inner tube 3.

[0022] The distal tip 4 is preferably made of a flexible material.

[0023] Examples of materials constituting the distal tip 4 include synthetic resins such as polyolefin resins such as polyethylene and polypropylene; polyamide resins such as nylon; polyester resins such as polyethylene terephthalate (PET); aromatic polyether ketone resins such as polyether ether ketone resin (PEEK); polyether polyamide resins; polyurethane resins; polyimide resins; fluorine-based resins such as polytetrafluoroethylene (PTFE), perfluoroalkoxyalkane (PFA), and ethylene tetrafluoroethylene copolymer (ETFE); polyvinyl chloride resins; and silicone resins. These materials may be used alone or in combination. Among these, polyamide resins are preferred, and polyamide elastomers are more preferred. By configuring the distal tip 4 in this manner, the medical tubular body transport device 1 can be configured to achieve both the ability of the distal tip 4 to follow the guidewire and safety at the distal end.

[0024] The distal tip 4 may be made up of one member or two or more members. The distal tip 4 is preferably made up of two or more members (particularly, two members). The distal tip 4 preferably has a taper in which the outer diameter decreases from the proximal side to the distal side. This can improve the passability of the medical tubular body delivery device 1 into a biological lumen.

[0025] The tip 4 is fixed to the distal end of the inner tube 3 via an adhesive material 5 .

[0026] The material for the inner tube 3 can be a known resin, such as a polyolefin resin (e.g., polyethylene, polypropylene, etc.); a polyamide resin (e.g., nylon); a polyester resin (e.g., polyethylene terephthalate (PET)); an aromatic polyether ketone resin (e.g., polyether ether ketone resin (PEEK)); a polyether polyamide resin; a polyurethane resin; a polyimide resin; a fluorine-containing resin (e.g., polytetrafluoroethylene (PTFE), perfluoroalkoxyalkane (PFA), ethylene tetrafluoroethylene copolymer (ETFE)); a polyvinyl chloride resin; a silicone resin; or a synthetic resin, such as natural rubber. These materials may be used alone or in combination. Of these, polyolefin resins, polyamide resins, aromatic polyether ketone resins, polyurethane resins, and fluorine-containing resins are preferred for the material for the inner tube 3. By containing at least one of polyolefin resin, polyamide resin, aromatic polyether ketone resin, polyurethane resin, and fluorine resin, the slipperiness of the inner surface of the inner tube 3 is improved, making it easier to insert a guide wire into the lumen of the inner tube 3 and feed the medical tubular body transport device 1 into the body along the guide wire.

[0027] The inner tube 3 may have a single layer structure or a multi-layer structure. In the case of a multi-layer structure, for example, a structure in which a braided layer such as a metal braid is provided as an intermediate layer of the inner tube 3 can be mentioned. The multi-layer structure can improve the tensile strength of the inner tube 3, as well as the slipperiness and kink resistance of the inner tube 3. Examples of metal braids include stainless steel, carbon steel, and nickel-titanium alloy. Of these, stainless steel is preferred.

[0028] The rigidity of the inner tube 3 on the distal side is preferably lower than the rigidity of the inner tube 3 on the proximal side. Increasing the rigidity of the inner tube 3 on the proximal side can improve the pushability of the medical tubular object delivery device 1. In order to reduce the rigidity of the inner tube 3 on the distal side, the inner tube 3 can be configured to include a distal inner tube and a proximal inner tube, with the rigidity of the distal inner tube being lower than the rigidity of the proximal inner tube. For example, the distal inner tube can have a single-layer structure made of synthetic resin, and the proximal inner tube can have a multi-layer structure with the above-mentioned metal braid as an intermediate synthetic resin layer.

[0029] It is preferable that a portion of the adhesive material 5 further extends inward beyond the inner surface 3a of the inner tube 3. By having the adhesive material 5 further extend inward beyond the inner surface 3a of the inner tube 3, it is possible to prevent the guide wire from wobbling.

[0030] The adhesive material 5 only needs to extend inward beyond the inner surface 3a of the inner tube 3. The adhesive material 5 may extend over the entire inner circumference of the inner tube 3, but preferably extends over part of the inner circumference of the inner tube 3. By having part of the adhesive material extend over part of the inner circumference of the inner tube 3, performance is improved in both suppressing guidewire wobble and ensuring slidability.

[0031] When the adhesive material 5 extends onto a portion of the inner circumference of the inner tube 3, it may extend to one location or to two or more locations, but it preferably extends to two or more locations, which can further suppress vibration of the guidewire.

[0032] When the adhesive material 5 extends from two or more locations on the inner circumference of the inner tube 3, the positions from which the adhesive material 5 extends may be equally or unequally spaced in the circumferential direction, but equally spaced positions are preferred, as the guidewire can be held at its axial center position more easily.

[0033] In the medical tubular body delivery device 1 of the present invention, it is preferable that the void area S2 of the lumen in a cross section perpendicular to the longitudinal axis direction x at position s2 where a portion of the adhesive material 5 extends inward beyond the inner surface 4a of the distal tip 4, the void area S1 of the lumen of the distal tip 4 in a cross section perpendicular to the longitudinal axis direction x at position s1 distal to position s2 where a portion of the adhesive material 5 extends inward beyond the inner surface 4a of the distal tip 4, and the void area S3 of the lumen of the inner tube 3 in a cross section perpendicular to the longitudinal axis direction x at position s3 proximal to position s2 where a portion of the adhesive material 5 extends inward beyond the inner surface 4a of the distal tip 4 satisfy the relationship represented by the following formula. S2 <S1≦S3

[0034] When the gap area S1, the gap area S2, and the gap area S3 satisfy the relationship expressed by the above formula, vibration of the guide wire can be prevented.

[0035] The void area S2 of the lumen in a cross section perpendicular to the longitudinal axis direction x at position s2 where a portion of the adhesive material 5 extends inward beyond the inner surface 4a of the tip 4 is smaller than the void area S1 of the lumen of the tip 4 in a cross section perpendicular to the longitudinal axis direction x at position s1 distal to position s2 where a portion of the adhesive material 5 extends inward beyond the inner surface 4a of the tip 4, and the void area S2 is preferably 99% or less, more preferably 98% or less, and even more preferably 97% or less, of the void area S1 taken as 100%. There is no particular lower limit to the ratio of the void area S2 to the void area S1, but the void area S2 is preferably 95% or more, more preferably 96% or more, and even more preferably 97% or more, of the void area S1 taken as 100%.

[0036] The void area S3 of the lumen of the inner tube 3 in a cross section perpendicular to the longitudinal axis direction x at position s3 proximal to position s2 where a portion of the adhesive material 5 extends inward beyond the inner surface 4a of the distal tip 4 is preferably the same as or larger than the void area S1 of the lumen of the distal tip 4 in a cross section perpendicular to the longitudinal axis direction x at position s1 distal to position s2 where a portion of the adhesive material 5 extends inward beyond the inner surface 4a of the distal tip 4, and more preferably the void area S3 is the same as the void area S1. When the void area S1 is taken as 100%, the void area S3 is preferably 110% or less, more preferably 108% or less, even more preferably 107% or less, and most preferably 100%. That is, it is preferable that the lumen diameter d3 of the inner tube 3 at position s3 proximal to position s2 where a portion of the adhesive material 5 extends inward beyond the inner surface 4a of the tip 4 is the same as or larger than the lumen diameter d1 of the tip 4 at position s1 distal to position s2 where a portion of the adhesive material 5 extends inward beyond the inner surface 4a of the tip 4, and it is more preferable that the lumen diameter d3 is the same as the lumen diameter d1.

[0037] The void area S1, the void area S2, and the void area S3 may be calculated, for example, by photographing a cross section at each position and analyzing the image.

[0038] The distal end of the inner tube 3 and the proximal end of the tip 4 may be butted against each other, but as shown in Figure 1, it is preferable that the outside of the distal end of the inner tube 3 is covered by the proximal end of the tip 4. This firmly fixes the tip 4 to the inner tube 3, making it difficult for the tip 4 to come off.

[0039] The ratio of the length L2 of the inner tube 3 covered by the distal tip 4 in the longitudinal direction x to the length L1 of the distal tip 4 in the longitudinal direction x is preferably 10% or more, more preferably 15% or more, and even more preferably 20% or more. The ratio of the length L2 to the length L1 is preferably 65% ​​or less, more preferably 60% or less, and even more preferably 55% or less.

[0040] A radiopaque marker is preferably provided at the distal end of the inner tube 3. This makes it easier to grasp the position of the distal tip 4. When the distal end of the inner tube 3 and the proximal end of the distal tip 4 are butted against each other, the radiopaque marker is preferably provided at the distal end of the inner tube 3; when the outside of the distal end of the inner tube 3 is covered by the proximal end of the distal tip 4, the radiopaque marker is preferably provided in the region of the distal end of the inner tube 3 that is covered by the distal tip 4 or at a position corresponding to the proximal end of the distal tip 4.

[0041] The shape of the radiopaque marker is not particularly limited, and may be cylindrical, or may be a tube whose cross section perpendicular to the long axis direction x has a C-shape.

[0042] The radiopaque marker contains a radiopaque substance, and examples of the radiopaque substance include lead, barium, iodine, tungsten, gold, platinum, iridium, stainless steel, titanium, cobalt-chromium alloy, etc. Among these, it is preferable that the radiopaque marker contains platinum.

[0043] An outer tube 2 is disposed on the outside of the inner tube 3, and a medical tubular body (not shown) is disposed in the lumen of the outer tube 2.

[0044] The material for the outer tube 2 can be a known resin, and examples thereof include synthetic resins such as polyolefin resins such as polyethylene and polypropylene; polyamide resins such as nylon; polyester resins such as PET; aromatic polyether ketone resins such as PEEK; polyether polyamide resins; polyurethane resins; polyimide resins; fluorine-based resins such as PTFE, PFA, and ETFE; and polyvinyl chloride resins. Among these, the material for the outer tube 2 is preferably a polyamide resin such as nylon or a polyether polyamide resin. Use of a polyamide resin or a polyether polyamide resin provides high strength, good wear resistance, a low coefficient of friction, and improved processability.

[0045] The outer tube 2 may have a single-layer structure or a multi-layer structure. Examples of multi-layer structures include a structure in which a braided layer such as a metal braid is provided as an intermediate layer of the outer tube 2, and a structure in which a fluororesin is provided as an inner layer and a polyamide resin is provided as an outer layer. The multi-layer structure can improve the tensile strength of the outer tube 2, as well as the slipperiness and kink resistance of the outer tube 2. Examples of metal braids include stainless steel, carbon steel, and nickel-titanium alloys. Of these, stainless steel is preferred.

[0046] The outer diameter of the outer tube 2 is, for example, preferably 0.5 mm or more, more preferably 0.7 mm or more, and even more preferably 1.0 mm or more. When the inner diameter of the outer tube 2 is constant, increasing the outer diameter of the outer tube 2 allows the wall thickness of the outer tube 2 to be increased, thereby increasing the tensile strength of the outer tube 2. The outer diameter of the outer tube 2 is, for example, preferably 3.5 mm or less, more preferably 3.3 mm or less, and even more preferably 3.0 mm or less. By setting the outer diameter of the outer tube 2 within this range, the outer diameter of the medical tubular body delivery device 1 on the distal side can be prevented from becoming too large, thereby improving the minimally invasive nature of the medical tubular body delivery device 1. Furthermore, the rigidity of the medical tubular body delivery device 1 on the distal side can be prevented from becoming too large, thereby improving operability during delivery into the body.

[0047] The wall thickness of the outer tube 2 is, for example, preferably 10 μm or more, more preferably 30 μm or more, and even more preferably 50 μm or more. By setting the wall thickness of the outer tube 2 within this range, the tensile strength of the outer tube 2 can be increased, and the safety of the medical tubular body transport device 1 can be improved. The wall thickness of the outer tube 2 is, for example, preferably 350 μm or less, more preferably 300 μm or less, and even more preferably 250 μm or less. By setting the wall thickness of the outer tube 2 within this range, the lumen of the outer tube 2 can be widened, thereby increasing the variety of diameters of medical tubular bodies that can be housed in the lumen of the outer tube 2, and enabling a variety of medical tubular bodies to be transported by the medical tubular body transport device 1.

[0048] The wall thickness of the inner tube 3 may be smaller or larger than that of the outer tube 2, but is preferably the same as that of the outer tube 2.

[0049] Examples of medical tubular bodies disposed within the lumen of the outer tube 2 include stents, stent grafts, occluders, injection catheters, and prosthetic valves. Stents are generally used to treat various diseases caused by narrowing or obstruction of lumens within the body, such as the digestive tract (e.g., the bile duct) or blood vessels. Examples of stents include coil-shaped stents made from a single metal wire, stents cut out of a metal tube with a laser, stents assembled by laser welding linear members, stents woven from multiple metal wires, and stents of the same shape as these metal stents but made from a polymeric material. A self-expanding stent is preferably used. A self-expanding stent is a stent that can expand by itself by removing the outer tube 2 that inhibits the stent's expansion.

[0050] Next, an example of a method for manufacturing the medical tubular body transport device according to the present invention will be described.

[0051] The medical tubular body delivery device according to the present invention can be manufactured by a method including the steps of inserting a core into the lumen of an inner tube (hereinafter sometimes referred to as a core inserting step), applying an adhesive material to the outside of the distal end of the inner tube (hereinafter sometimes referred to as an adhesive material applying step), applying a distal tip to the outside of the distal end of the inner tube (hereinafter sometimes referred to as a distal tip applying step), and fixing the distal end of the inner tube and the distal tip (hereinafter sometimes referred to as a distal tip fixing step). Each step will be described below.

[0052] [Core material insertion process] In the core insertion step, the core 6 is inserted into the lumen of the inner tube 3. Figure 2 is a cross-sectional view showing the state in which the core has been inserted into the lumen of the inner tube 3. In Figure 2, the right side of the arrow x is the proximal side, and the left side of the arrow x is the distal side. The same members as in Figure 1 are given the same reference numerals to avoid redundant explanation.

[0053] The inner tube 3 extends in the distal and proximal directions, and a core material 6 is inserted into the lumen at least at the distal end of the inner tube 3. By disposing the core material 6 in the lumen of the inner tube 3, it is possible to prevent the lumen of the inner tube 3 from decreasing.

[0054] The core material 6 inserted into the lumen of the inner tube 3 may have a butting member 6a disposed at its distal end. When the butting member 6a is disposed at the distal end of the core material 6, it is preferable that the core material 6 is inserted into the distal end of the inner tube 3 in a state in which the proximal end face of the butting member 6a does not contact the distal end face of the inner tube 3, and a gap is left between the proximal end face of the butting member 6a and the distal end face of the inner tube 3. By leaving a gap between the proximal end face of the butting member 6a and the distal end face of the inner tube 3, in a later step, a portion of the adhesive material 5 can extend inward beyond the inner surface 4a of the distal tip 4. This reduces vibration of the guidewire.

[0055] When a butting member 6a is arranged at the distal end of the core material 6, the gap distance between the proximal end face of the butting member 6a and the distal end face of the inner tube 3 is, for example, preferably 0.05 mm to 5 mm, more preferably 0.08 mm or more, even more preferably 0.1 mm or more, more preferably 3 mm or less, and even more preferably 1 mm or less.

[0056] The material of the core member 6 and the abutting member 6a is not particularly limited, but for example, metal materials such as copper, silver, aluminum, stainless steel, etc. can be used.

[0057] [Adhesive material placement process] In the adhesive material placement step, adhesive material 5 is placed on the outside of the distal end of inner tube 3 .

[0058] The shape of the adhesive material 5 is not particularly limited, and various shapes can be used, such as a film, belt, sheet, powder, thread, net, ring, cylinder, liquid, etc. Among these, a film, belt, sheet, ring, cylinder, or liquid shape is preferred.

[0059] When the adhesive material 5 has a cylindrical shape, for example, it is preferable that when the cylindrical adhesive material 5 is placed on the outside of the distal end of the inner tube 3, the cylindrical adhesive material 5 covers at least a portion of the tip surface of the inner tube 3 so that a portion of the adhesive material 5 extends inward beyond the inner surface 4a of the tip tip 4.

[0060] [Tip placement process] In the tip arrangement step, the tip 4 is arranged on the outside of the distal end of the inner tube 3. When the adhesive material 5 is in a liquid form, for example, by arranging the tip 4 on the outside of the distal end of the inner tube 3, the liquid adhesive material 5 will ooze out from the abutting portion between the tip 4 and the inner tube 3 to a position inside the inner surface 4a of the tip 4.

[0061] [Tip fixing process] In the tip fixing step, the tip 4 is fixed to the distal end of the inner tube 3. The tip 4 is fixed to the distal end of the inner tube 3 via the adhesive material 5.

[0062] After the distal tip 4 is fixed, the outer tube 2 can be placed on the outside of the inner tube 3 in accordance with a known method, and a medical tubular body can be placed in the lumen of the outer tube 2. When placing the outer tube 2 on the outside of the inner tube 3, a medical tubular body can be placed in the lumen of the outer tube 2 in advance, and the outer tube 2 with this medical tubular body placed in the lumen can be placed on the outside of the inner tube 3.

[0063] In the adhesive material placement step, after the adhesive material 5 is placed on the outside of the distal end of the inner tube 3, the core material 6 may be left in place in the lumen of the inner tube 3, or the core material 6 may be removed from the lumen of the inner tube 3. If the core material 6 has been removed from the lumen of the inner tube 3, the core material 6 may be placed again on the distal tip 4 and the distal end of the inner tube 3 when the distal end of the inner tube 3 and the distal tip 4 are fixed in the distal tip fixing step. [Explanation of symbols]

[0064] 1 Medical tubular body transport device 2 outer tubes 3 Inner Tube 3a Inner surface of inner tube 4 Tip 4a Inner surface of tip 5 Adhesive materials 6 Core material 6a Stopper x Long axis direction

Claims

1. A medical tubular body delivery device for delivering a medical tubular body into a body, comprising: an outer tube disposed in the lumen of the medical tubular body; an inner tube disposed within the lumen of the outer tube; a distal tip fixed to the distal end of the inner tube via an adhesive material; It has the distal tip has a lumen extending in a longitudinal direction, the lumen communicating with the lumen of the inner tube; A medical tubular body delivery device, wherein a portion of the adhesive material extends inward beyond the inner surface of the distal tip.

2. 2. The medical tubular body delivery device according to claim 1, wherein a portion of the adhesive material extends inward beyond the inner surface of the inner tube.

3. 3. The medical tubular body delivery device according to claim 1, wherein a portion of the adhesive material extends onto a portion of the inner periphery of the distal tip.

4. 4. The medical tubular body delivery device according to claim 1, wherein a portion of the adhesive material extends inward beyond the inner surface of the inner tube and extends onto a portion of the inner circumference of the inner tube.

5. a gap area S1 of the lumen of the distal tip in a cross section perpendicular to the longitudinal axis direction at a position distal to a position where a portion of the adhesive material extends inward beyond the inner surface of the distal tip; a gap area S2 of the lumen in a cross section perpendicular to the longitudinal axis direction at a position where a portion of the adhesive material extends inward beyond the inner surface of the distal tip; A medical tubular body transport device as described in any one of claims 1 to 4, wherein the void area S3 of the inner tube lumen in a cross section perpendicular to the longitudinal axis direction proximal to the position where a portion of the adhesive material extends inward beyond the inner surface of the distal tip satisfies the relationship expressed by the following formula. S2<S1≦S3

6. 6. The medical tubular body delivery device according to claim 1, wherein the outside of the distal end of the inner tube is covered with the proximal end of the distal tip.

7. 7. The medical tubular body delivery device according to claim 1, wherein an X-ray opaque marker is provided at the distal end of said inner tube.

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