Aerosol for controlling creeping pests

Abstract

To provide a method for controlling creeping pests, which can effectively control creeping pests, particularly bedbugs, which have the habit of hiding in gaps, by using a constant-amount spray type aerosol. [Solution] This is a method for controlling crawling pests using a metered-dose aerosol, which is obtained by filling an aerosol container equipped with a metered-dose valve with crawling pest control ingredients including a 2,3,5,6-tetrafluorobenzyl ester compound (component A) and a 3-phenoxybenzyl ester compound (component B), an aerosol concentrate containing a solvent, and a propellant. When the content of component A in the aerosol concentrate is a, the content of component B is b, and the content of the solvent is c, δ, defined as δ = b / (a + c), satisfies 0.45 to 4.00, and when the filling volume of the aerosol concentrate is L and the filling volume of the propellant is G, 0.1≦L / (L + G)≦0.5 is satisfied. This is a method for controlling crawling pests, in which the aerosol is sprayed indoors into an open space.

Description

[Technical Field]

[0001] The present invention relates to a method for controlling crawling pests such as bedbugs using a constant-dose aerosol, and to an aerosol for controlling crawling pests such as bedbugs. [Background technology]

[0002] In recent years, the spread of bed bugs in some hotels and lodgings has become a social problem, and urgent countermeasures are required. Targeting bed bugs that roam floors and walls and hide in gaps, insecticides that are applied to places where bed bugs live or pass through have traditionally been (1) fumigants, (2) total-amount aerosol sprays, and (3) topical aerosol sprays, each with its own formulation characteristics.

[0003] (1) Fumigants and (2) total-discharge aerosols fall into the category of pharmaceuticals because they instantly diffuse the chemicals throughout a room, sealing the room for a specified period of time to increase the chemical concentration, and prohibit people from entering the room during that time. These formulations are characterized by their spatial treatment, in that the diffused chemicals are highly effective in eliminating bed bugs throughout the entire treatment space. However, these formulations require time and effort, such as preserving electrical appliances and tableware before treatment and cleaning up the sprayed sediment after treatment. Furthermore, special attention must be paid to the safety of the chemicals, making them difficult to say that they are formulations that can be easily and frequently adopted.

[0004] On the other hand, (3) topical aerosols, which are used for localized treatment, are mostly quasi-drugs with mild effects on the human body, and are valued for their ease of use. For example, topical aerosols that combine pest control ingredients with specific saturated aliphatic hydrocarbons are known to be able to control bedbugs (see, for example, Patent Document 1).

[0005] Furthermore, as a method for exterminating crawling pests with a smaller amount of chemical than (1) fumigants or (2) total-amount spray aerosols, a crawling pest extermination method is known in which an insecticide liquid containing an insecticidal component and a solvent is dispersed little by little over time using a piezoelectric sprayer (see, for example, Patent Document 2). The pest extermination method of Patent Document 2 is said to be able to exterminate crawling pests by continuously suspending small particles of insecticide liquid in a space such as an indoor space or a storage space. [Prior art documents] [Patent documents]

[0006] [Patent Document 1] Japanese Patent Application Laid-Open No. 2013-170140 [Patent Document 2] Japanese Patent Application Laid-Open No. 2009-143868 Summary of the Invention [Problem to be solved by the invention]

[0007] However, the application-type aerosol of Patent Document 1 is not a spatial treatment like (1) fumigants or (2) total-volume spray aerosols, but is a so-called local treatment that has an extermination effect on bed bugs only at the location where the chemical is applied. Therefore, the contact efficiency between the chemical and bed bugs is inferior to (1) fumigants or (2) total-volume spray aerosols, and it does not necessarily provide an efficient extermination method.

[0008] The crawling pest extermination method of Patent Document 2 proposes to exterminate cockroaches by continuously diffusing a small amount of chemical into the air over a long period of time, like a liquid electric mosquito repellent, but since it targets cockroaches that are resistant to chemicals, it is necessary to use a strong insecticidal ingredient, which inevitably raises concerns about safety to humans.In addition, bedbugs have different ecology and habits from cockroaches, so the method of Patent Document 2 may not necessarily be able to exterminate bedbugs effectively.

[0009] Thus, there is a need for the development of a crawling pest control agent that is an easy-to-use quasi-drug that provides spatial treatment with excellent contact efficiency between the agent and bedbugs, but none of these has yet been put into practical use.

[0010] The present invention has been made in consideration of the above-mentioned problems, and aims to provide a method for controlling creeping pests, which can effectively control creeping pests that have the habit of hiding in gaps, particularly bedbugs, using a fixed-dose aerosol, and an aerosol for controlling creeping pests. [Means for solving the problem]

[0011] The characteristic configuration of the crawling pest control method according to the present invention for solving the above problems is as follows: A method for controlling crawling pests using a constant-dose aerosol, which is obtained by filling an aerosol concentrate containing a crawling pest control component and a solvent, and a propellant into an aerosol container equipped with a constant-dose injection valve, The creeping pest control component is represented by the general formula (I): [ka] [wherein X represents a hydrogen atom, a methyl group, or a methoxymethyl group; R 1 and R 2 and each represent a hydrogen atom, a halogen atom, an alkyl group having 1 to 3 carbon atoms, a haloalkyl group having 1 to 3 carbon atoms, or a cyano group.], and a 2,3,5,6-tetrafluorobenzyl ester compound represented by the general formula (II): [ka] [wherein Y represents a hydrogen atom or a cyano group, Z represents a hydrogen atom or a fluorine atom, and R 3 and R 4 and each represent a hydrogen atom, a halogen atom, an alkyl group having 1 to 3 carbon atoms, or a haloalkyl group having 1 to 3 carbon atoms. The aerosol can be prepared by weight as follows: a) the content of the 2,3,5,6-tetrafluorobenzyl ester compound in the aerosol concentrate; b) the content of the 3-phenoxybenzyl ester compound; and c) the content of the solvent in the aerosol concentrate. δ = b / (a+c) (1) δ, defined as 0.45 to 4.00, When the filling volume of the aerosol concentrate is L and the filling volume of the propellant is G, the following formula (2) is used: 0.1 ≦ L / (L+G) ≦ 0.5 (2) It is configured to satisfy The aerosol is sprayed indoors into a space.

[0012] According to the method for controlling creeping pests of this configuration, spatial treatment is performed using a metered-amount aerosol, allowing for highly safe treatment for controlling creeping pests even in situations where people are present. Furthermore, by using a combination of a 2,3,5,6-tetrafluorobenzyl ester compound, which has relatively high volatility, and a 3-phenoxybenzyl ester compound, which is less volatile, as the creeping pest control component, the creeping pest control component adheres to floors and walls, thereby enhancing the control effect against creeping pests such as bedbugs that roam floors and walls. Furthermore, by combining the above-mentioned specific crawling pest control components and solvents so that δ calculated from the above formula (1), which uses the content of each component of the aerosol concentrate as a parameter, falls within the above range, and by setting the value of the above formula (2), which uses the filling volume of the aerosol concentrate and propellant as parameters, within the above range, an unexpected synergistic effect can be achieved, which not only provides excellent control effects against crawling pests such as bed bugs that roam floors and walls, but also makes it possible to effectively control crawling pests such as bed bugs that hide in crevices.

[0013] In the creeping pest control method according to the present invention, The solvent is preferably a lower alcohol having 2 to 3 carbon atoms or a higher fatty acid ester having 16 to 20 carbon atoms.

[0014] According to the crawling pest control method of this configuration, the solvent is a lower alcohol having 2 to 3 carbon atoms or a higher fatty acid ester having 16 to 20 carbon atoms, which makes it easier for the spray particles to enter gaps, thereby providing excellent control effects against crawling pests such as bed bugs that hide in gaps.

[0015] In the creeping pest control method according to the present invention, The creeping pest is preferably a bedbug.

[0016] According to the method for controlling creeping pests of this configuration, an excellent control effect can be exhibited against creeping pests, particularly bedbugs.

[0017] The characteristic configuration of the aerosol spray for controlling crawling pests according to the present invention to solve the above problems is as follows: General formula (I): [ka] [wherein X represents a hydrogen atom, a methyl group, or a methoxymethyl group; R 1 and R 2 and each represent a hydrogen atom, a halogen atom, an alkyl group having 1 to 3 carbon atoms, a haloalkyl group having 1 to 3 carbon atoms, or a cyano group.], and a 2,3,5,6-tetrafluorobenzyl ester compound represented by the general formula (II): [ka] [wherein Y represents a hydrogen atom or a cyano group, Z represents a hydrogen atom or a fluorine atom, and R 3 and R 4 and each represent a hydrogen atom, a halogen atom, an alkyl group having 1 to 3 carbon atoms, or a haloalkyl group having 1 to 3 carbon atoms.], and an aerosol concentrate containing a solvent and a propellant are filled in an aerosol container equipped with a metered injection valve, When the weight of the content of the 2,3,5,6-tetrafluorobenzyl ester compound in the aerosol concentrate is a, the weight of the content of the 3-phenoxybenzyl ester compound is b, and the weight of the content of the solvent in the aerosol concentrate is c, the following formula (1) is satisfied: δ = b / (a+c) (1) δ, defined as 0.45 to 4.00, When the filling volume of the aerosol concentrate is L and the filling volume of the propellant is G, the following formula (2) is used: 0.1 ≦ L / (L+G) ≦ 0.5 (2) The object of the present invention is to provide a method for manufacturing a semiconductor device using the above-mentioned semiconductor device.

[0018] According to the aerosol for controlling crawling pests of this configuration, by using a combination of a 2,3,5,6-tetrafluorobenzyl ester compound, which has relatively high volatility, and a 3-phenoxybenzyl ester compound, which is difficult to volatilize, as the crawling pest control component, the crawling pest control component adheres to floors and walls, thereby enhancing the control effect against crawling pests such as bedbugs that roam floors and walls. Furthermore, by combining the above-mentioned specific crawling pest control components and solvents so that δ calculated from the above formula (1), which uses the content of each component of the aerosol concentrate as a parameter, falls within the above range, and by setting the value of the above formula (2), which uses the filling volume of the aerosol concentrate and propellant as parameters, within the above range, an unexpected synergistic effect can be achieved, which not only provides excellent control effects against crawling pests such as bed bugs that roam floors and walls, but also makes it possible to effectively control crawling pests such as bed bugs that hide in crevices.

[0019] In the aerosol for controlling creeping pests according to the present invention, The solvent is preferably a lower alcohol having 2 to 3 carbon atoms or a higher fatty acid ester having 16 to 20 carbon atoms.

[0020] According to the aerosol for controlling crawling pests of this configuration, the solvent is a lower alcohol having 2 to 3 carbon atoms or a higher fatty acid ester having 16 to 20 carbon atoms, which makes it easier for the spray particles to enter gaps, and it can exert an excellent control effect against crawling pests such as bed bugs that hide in gaps.

[0021] In the aerosol for controlling creeping pests according to the present invention, The spray force at a spray distance of 5 cm is preferably set to 3 to 50 gf.

[0022] With this type of aerosol for controlling creeping pests, by setting the spray force at a spray distance of 5 cm to 3 to 50 gf, a sufficient amount of creeping pest control ingredients will adhere to the floor and wall surfaces, and the creeping pest control ingredients will reach the gaps in the treatment space, thereby providing a practically sufficient control effect against both creeping pests such as bed bugs that wander on the floor and those that hide in gaps.

[0023] In the aerosol for controlling creeping pests according to the present invention, The creeping pest is preferably a bedbug.

[0024] The aerosol for controlling creeping pests having this configuration can exert an excellent control effect against creeping pests, particularly bedbugs. DETAILED DESCRIPTION OF THE INVENTION

[0025] The method for controlling creeping pests and the aerosol for controlling creeping pests of the present invention will be described below, although it is not intended that the present invention be limited to the configurations described below.

[0026] [Formulation of aerosol for controlling creeping pests] The aerosol for controlling creeping pests of the present invention is a metered-dose type aerosol used to control creeping pests such as bed bugs by spatial treatment, and is configured by filling an aerosol concentrate containing a creeping pest control component and a solvent, and a propellant, into an aerosol container equipped with a metered-dose valve. Here, "spatial treatment" in the present invention refers to a treatment in which the creeping pest control component is widely dispersed throughout the treatment space, thereby controlling creeping pests such as bed bugs throughout the entire treatment space. Compared to local treatment in which the control component is applied locally and creeping pests are controlled only in the area where the control component is applied, spatial treatment has superior contact efficiency with creeping pests, and therefore can be expected to have a high control effect, but attention must be paid to the safety of people in the treatment space. In the crawling pest control method of the present invention, a metered-amount aerosol is sprayed indoors into the air, which allows for practically sufficient control of crawling pests such as bedbugs, while the amount of agent is less than that of fumigants or total-amount aerosols, resulting in a milder effect on the human body. In this specification, the term "control effect" refers to the control effect based on the knockdown effect and lethal effect, as well as the repellent effect. Even if the control effect is low, sufficient repellent effect can often achieve practical control.

[0027] <Concentrated aerosol> The crawling pest control component, which is one of the main components of the aerosol concentrate, is represented by the general formula (I): [ka] [wherein X represents a hydrogen atom, a methyl group, or a methoxymethyl group; R 1 and R 2 and each represent a hydrogen atom, a halogen atom, an alkyl group having 1 to 3 carbon atoms, a haloalkyl group having 1 to 3 carbon atoms, or a cyano group.] and a 2,3,5,6-tetrafluorobenzyl ester compound having a common skeleton represented by the general formula (II): [ka] [wherein Y represents a hydrogen atom or a cyano group, Z represents a hydrogen atom or a fluorine atom, and R 3 and R4 and each represent a hydrogen atom, a halogen atom, an alkyl group having 1 to 3 carbon atoms, or a haloalkyl group having 1 to 3 carbon atoms.] When a certain amount of the aerosol for controlling crawling pests of the present invention is sprayed into an indoor treatment space, the spray particles mainly settle on the floor surface as adhesive particles, but by using a combination of compounds with different common skeletons, namely, a 2,3,5,6-tetrafluorobenzyl ester compound represented by general formula (I) and a 3-phenoxybenzyl ester compound represented by general formula (II), as crawling pest control ingredients, the control effect against crawling pests such as bed bugs that crawl on floors and walls can be improved.

[0028] Examples of 2,3,5,6-tetrafluorobenzyl ester compounds represented by general formula (I) include metofluthrin, transfluthrin, profluthrin, momfluorothrin, dimefluthrin, tefluthrin, heptafluthrin, and mepafluthrin. Among these, metofluthrin, transfluthrin, and profluthrin are preferred in consideration of volatility (vapor pressure), stability, basic insecticidal efficacy, and the like. The above-mentioned 2,3,5,6-tetrafluorobenzyl ester compounds can be used alone or in combination. In addition, when optical isomers based on asymmetric carbons or geometric isomers based on double bonds exist in the acid moiety or alcohol moiety of a 2,3,5,6-tetrafluorobenzyl ester compound, each of these isomers and any mixture thereof are also encompassed in the present invention.

[0029] Examples of the 3-phenoxybenzyl ester compound represented by general formula (II) include fenothrin, cyphenothrin, permethrin, cypermethrin, deltamethrin, cyhalothrin, and cyfluthrin. Among these, fenothrin, permethrin, and cyphenothrin are preferred. The above 3-phenoxybenzyl ester compounds can be used alone or in combination. In addition, when optical isomers based on asymmetric carbons or geometric isomers based on double bonds exist in the acid moiety or alcohol moiety of the 3-phenoxybenzyl ester compound, each of these isomers and any mixture thereof are also encompassed in the present invention.

[0030] The total content of the crawling pest control component in the aerosol concentrate, which is the 2,3,5,6-tetrafluorobenzyl ester compound and the 3-phenoxybenzyl ester compound, is preferably 30 to 75 w / v%. If the content of the crawling pest control component in the aerosol concentrate is within the above range, when the aerosol is sprayed, the spray particles are formed in an optimal state for controlling crawling pests such as bedbugs, and an appropriate control effect can be obtained. If the content of the crawling pest control component in the aerosol concentrate is less than 30 w / v%, there is a risk that the crawling pest control component released into the treatment space will be insufficient, and sufficient control effect will not be obtained. If the content of crawling pest control ingredients in the aerosol concentrate exceeds 75 w / v%, there is a risk that when the aerosol is sprayed, the spray particles will not be formed in an optimal state for controlling crawling pests such as bedbugs.

[0031] Examples of solvents, which are one of the main components of aerosol concentrates, include lower alcohols having 2 to 3 carbon atoms, hydrocarbon solvents (such as normal paraffin solvents and isoparaffin solvents), higher fatty acid esters having 16 to 20 carbon atoms, glycol ether solvents having 3 to 10 carbon atoms, and ketone solvents. Lower alcohols having 2 to 3 carbon atoms or higher fatty acid esters having 16 to 20 carbon atoms are preferred. The use of these solvents makes it easier for spray particles to enter gaps after spraying, thereby providing excellent control effects against crawling pests such as bed bugs that lurk in gaps. Examples of lower alcohols having 2 to 3 carbon atoms include ethanol, 1-propanol, and 2-propanol. Examples of higher fatty acid esters having 16 to 20 carbon atoms include isopropyl myristate, butyl myristate, and hexyl laurate. Among these, ethanol or isopropyl myristate is preferred from the viewpoint of ease of penetration into gaps, and ethanol is more preferred from the viewpoint of ease of penetration into gaps due to evaporation after spraying and a small particle size.

[0032] The aerosol concentrate has a mass expressed by the following formula (1): a represents the content of the 2,3,5,6-tetrafluorobenzyl ester compound, b represents the content of the 3-phenoxybenzyl ester compound, and c represents the content of the solvent. δ = b / (a+c) (1) The composition is prepared so that δ, as defined by the following formula (1), satisfies 0.45 to 4.00, and preferably satisfies 0.45 to 3.20. δ calculated from the above formula (1) is a parameter indicating the weight ratio of the hardly volatile component (3-phenoxybenzyl ester compound) to the highly volatile components (2,3,5,6-tetrafluorobenzyl ester compound and solvent) in the aerosol concentrate, and by combining the above-mentioned specific crawling pest control component and solvent so that the value of δ is 0.45 to 4.00, an unexpected synergistic effect can be achieved, making it possible to effectively control crawling pests such as bed bugs that crawl on floors and walls, as well as crawling pests such as bed bugs that hide in crevices.

[0033] In addition to the above components, the aerosol concentrate may also contain, as appropriate, antifungal agents, antibacterial agents, disinfectants, antiviral agents, fragrances, deodorizers, stabilizers, antistatic agents, antifoaming agents, excipients, etc. that target molds, fungi, viruses, etc. Examples of antifungal agents, antibacterial agents, disinfectants, and antiviral agents include hinokitiol, 2-mercaptobenzothiazole, 2-(4-thiazolyl)benzimidazole, 5-chloro-2-methyl-4-isothiazolin-3-one, triforine, 3-methyl-4-isopropylphenol, and ortho-phenylphenol. Further, examples of fragrances include aromatic components such as orange oil, lemon oil, lavender oil, peppermint oil, eucalyptus oil, citronella oil, lime oil, yuzu oil, jasmine oil, cypress oil, green tea essential oil, limonene, α-pinene, linalool, geraniol, phenylethyl alcohol, amyl cinnamic aldehyde, cumin aldehyde, and benzyl acetate, as well as fragrance components containing leaf alcohol and leaf aldehyde, known as "green scents."

[0034] The aerosol for controlling crawling pests of the present invention can also be formulated as a water-based formulation. In this case, the amount of water contained in the aerosol concentrate is preferably about 5 to 50 v / v %, and a small amount of a nonionic surfactant may be added as a solubilizing aid, as long as it does not affect the spray pattern of the spray particles. Examples of nonionic surfactants include ethers such as polyoxyethylene alkyl ethers, polyoxyethylene alkylphenyl ethers, polyoxyethylene polyoxypropylene alkyl ethers, and polyoxyethylene alkylamino ethers; fatty acid esters such as polyethylene glycol fatty acid esters, polyoxyethylene sorbitan fatty acid esters, and polyoxyethylene glycerin fatty acid esters; polyoxyethylene styrenated phenol; and polyalkalolamides of fatty acids. Among these, ethers are preferred.

[0035] <Propellant> Examples of propellants used in the aerosol spray for controlling creeping pests of the present invention include liquefied gases such as liquefied petroleum gas (LPG), dimethyl ether (DME), and hydrofluoroolefins, as well as nitrogen gas, carbon dioxide gas, nitrous oxide, and compressed air. Of these, liquefied gases are preferred. The above propellants can be used alone or in a mixture, but propellants containing LPG as the main component are easy to use.

[0036] The aerosol for controlling creeping pests of the present invention has a filling volume of the aerosol concentrate filled in the aerosol container defined as L and a filling volume of the propellant defined as G, and the filling volume of the aerosol for controlling creeping pests of the present invention is expressed as follows: 0.1 ≦ L / (L+G) ≦ 0.5 (2)

[0044] The formula (2) is configured to satisfy the following. By satisfying the above formula (2), a sufficient amount of the crawling pest control ingredient can be uniformly diffused throughout the floor, wall, and gaps within the treatment space. If [L / (L+G)] is less than 0.1, i.e., if a large amount of propellant is enclosed in the aerosol container, the spray particles formed from the sprayed aerosol concentrate may be unnecessarily fine, and there is a risk that the amount of crawling pest control ingredient adhering to the floor and wall may be insufficient. If [L / (L+G)] is greater than 0.5, i.e., if a small amount of propellant is enclosed in the aerosol container, the spray particles may become too large, and there is a risk that the crawling pest control ingredient will not reach the gaps sufficiently.

[0037] [Aerosol nozzle for controlling creeping pests] The shape (cross-sectional shape) of the nozzle of the aerosol for controlling creeping insect pests of the present invention is not particularly limited, but examples include circle, polygon such as square, ellipse, etc., and circle is preferable. Here, the nozzle diameter means the major axis of the ellipse when the nozzle shape is elliptical, and means the diameter of the circumscribed circle of the polygon when the nozzle shape is polygonal. The opening area of ​​the nozzle is 0.05 to 8.0 mm 2 It is preferable that the thickness is 0.1 to 4.0 mm. 2 More preferably, it is 0.2 to 3.0 mm 2It is more preferable that the nozzle diameter is 0.2 mm or more. For example, when there is one nozzle and the nozzle shape is circular, the nozzle size (nozzle diameter) is preferably 0.2 mm or more, more preferably 0.3 mm or more, and even more preferably 0.5 mm or more. The nozzle diameter is preferably 3.0 mm or less, more preferably 2.0 mm or less, and even more preferably 1.8 mm or less. If the nozzle diameter is 0.2 to 3.0 mm, the size of the spray particles is appropriate, and a sufficient amount of the crawling pest control component reaches gaps, making it possible to effectively control crawling pests such as bed bugs that lurk in gaps.

[0038] The number of nozzles in the aerosol for controlling crawling pests of the present invention may be one or two or more, but from the viewpoint of simple and low-cost production, it is preferable that the number of nozzles is one.

[0039] The nozzle of the aerosol for controlling crawling pests of the present invention has an elevation angle of the nozzle relative to the horizontal plane that is typically set to 0 to 60°, preferably 10 to 60°, and more preferably 15 to 50°. If the elevation angle of the nozzle relative to the horizontal plane is within the above range, poor spraying is unlikely to occur and the aerosol concentrate can be stably sprayed. The elevation angle of the nozzle relative to the horizontal plane of a nozzle or actuator having two nozzles is the elevation angle relative to the horizontal plane of the perpendicular bisector of the line segment connecting the centers of each nozzle. For nozzles or actuators having three or more nozzles, the elevation angle of the nozzle relative to the horizontal plane is defined as follows: For nozzles or actuators having a nozzle in the center of the nozzle's nozzle section, the elevation angle is the elevation angle relative to the horizontal plane of an orthogonal line passing through the center of the central nozzle. For nozzles or actuators having no nozzle in the center of the nozzle's nozzle section, the elevation angle is the elevation angle relative to the horizontal plane of an orthogonal line passing through the center of the circumscribing circle of a polygon connecting the centers of each nozzle.

[0040] The aerosol spray for controlling crawling pests of the present invention preferably has a spray force of 3 to 50 gf at a point 5 cm away from the nozzle, and more preferably 10 to 30 gf. A spray force of 3 to 50 gf ensures that a sufficient amount of crawling pest control component adheres to floor and wall surfaces, and that the crawling pest control component reaches gaps in the treatment space, providing a practically sufficient control effect against both crawling pests such as bed bugs that roam the floor and those that hide in gaps. In this embodiment, the spray force of the pest control aerosol was measured using a digital force gauge (FGC-0.5, manufactured by Nidec-Shimpo Corporation).

[0041] The aerosol for controlling creeping pests of the present invention preferably has a spray volume per spray from a metered spray valve of 0.1 to 5.0 mL, more preferably 0.2 to 3.0 mL, and even more preferably 0.2 to 1.0 mL. If the spray volume per spray is 0.1 to 5.0 mL, the aerosol can be sprayed in an amount of 18.8 to 33.3 m, for example, which corresponds to a room of 4.5 to 8 tatami mats in size. 3 (Area 7.5~13.3m 2 By spraying the aerosol for controlling creeping pests once or several times in a treatment space (a height of 2.2 to 3.0 m), the amount of creeping pest control ingredient released becomes appropriate, and a practically sufficient control effect against creeping pests can be obtained in the treatment space, and an excellent control effect against bed bugs in particular can be obtained. Furthermore, if the spray volume per spray is 0.1 to 5.0 mL, a treatment frequency of once every 1 to 7 days is sufficient.

[0042] In the aerosol sprayer for controlling crawling pests of the present invention, the shapes of the nozzle, container, etc. can be appropriately selected depending on the application, purpose of use, etc. For example, it can be a tabletop type with a button that is pressed from above and a nozzle that faces diagonally upward, or it can be designed as a small, portable container. Furthermore, the actuator for activating the aerosol sprayer for controlling crawling pests may or may not have a nozzle. If it has a nozzle, it may have a protruding nozzle or a non-protruding nozzle, but a protruding nozzle is preferred. In the case of an actuator with a nozzle, the length of the nozzle is not particularly limited, but is preferably 2.0 to 80 mm, more preferably 3.0 to 70 mm, and particularly preferably 4.0 to 60 mm. The operating button on the actuator can be a push-down type or a trigger type button.

[0043] [Crawling pest control method] The crawling pest control method of the present invention involves spraying a metered-dose aerosol containing a specific crawling pest control component and a solvent, such as the crawling pest control aerosol of the present invention, into a treatment space. When using fumigants or total-dose aerosols, people are not allowed to enter the treatment space during the chemical treatment, and the treatment space must be closed for 2 to 3 hours. In addition, electrical appliances and tableware must be cured before treatment, and sprayed sediment must be cleaned up after treatment. In contrast, the crawling pest control method of the present invention uses a metered-dose aerosol, which allows for a small amount of crawling pest control component to be sprayed into the treatment space. Therefore, the crawling pest control method of the present invention eliminates the pre-treatment preparation procedures and post-treatment cleanup required for fumigants and total-dose aerosols. Furthermore, since the creeping pest control method of the present invention uses a fixed-amount spray type aerosol to perform spatial treatment, treatment for crawling pest control can be safely carried out without leaving the indoor space that is the treatment space. In this way, the creeping pest control method of the present invention employs a spatial treatment method that is more effective than local treatment methods, while providing convenience that cannot be expected from spatial treatment using conventional fumigants or total-amount spray type aerosols.

[0044] In the method for controlling creeping pests of the present invention, when the aerosol for controlling creeping pests is sprayed indoors, the amount of the creeping pest control component released into the air is 0.1 to 50 mg / m 3 is preferably 0.5 to 50 mg / m 3 It is more preferable that the amount of the creeping pest control ingredient released into the air is within the above range, and it is possible to obtain an excellent control effect against creeping pests, particularly bed bugs, while maintaining high safety even in situations where people are present. When an aerosol for controlling creeping pests equipped with a metered injection valve with a single injection volume of 1.0 to 5.0 mL is used, it is possible to spray an aerosol for controlling creeping pests in an area of ​​18.8 to 33.3 m, which corresponds to a room of 4.5 to 8 tatami mats. 3 (Area 7.5~13.3m 2 When the method for controlling creeping pests of the present invention is carried out in an indoor treatment space (2.2 to 3.0 m in height), the amount of the creeping pest control component released into the air by one spray is usually 0.1 to 50 mg / m 3 In larger indoor treatment spaces, the amount of crawling insect control component released into the air is set to 0.1 to 50 mg / m according to the volume of the treatment space. 3 By spraying multiple times so as to obtain the same control effect regardless of the size of the treatment space, it is possible to obtain the same control effect regardless of the size of the treatment space. Even when an aerosol with a metered injection valve with a single injection volume of less than 1.0 mL, for example, 0.1 to 0.9 mL, is used, the amount of the crawling pest control component released into the air is 0.1 to 50 mg / m 3 By appropriately adjusting the number of sprays so that the number of sprays is equal to or greater than the number of sprays per minute, an excellent control effect against crawling pests, particularly bedbugs, can be obtained.

[0045] The creeping pest control method of the present invention is preferably carried out once every 1 to 7 days. As described above, the creeping pest control method of the present invention uses a creeping pest control component containing a 2,3,5,6-tetrafluorobenzyl ester compound and a 3-phenoxybenzyl ester compound in combination with a solvent (preferably a lower alcohol having 2 to 3 carbon atoms or a higher fatty acid ester having 16 to 20 carbon atoms) in combination, thereby achieving a synergistic effect that further improves the control effect against creeping pests, particularly bed bugs. Therefore, even if the method is carried out once every 1 to 7 days, a practically sufficient control effect against creeping pests can be expected, and excellent control effect against bed bugs in particular can be achieved. In this way, the creeping pest control method of the present invention can reduce the frequency of application of a creeping pest control aerosol.

[0046] In the method for controlling creeping pests of the present invention, the aerosol for controlling creeping pests is preferably sprayed so that the spray direction angle with respect to the horizontal plane is 0 to 60°, more preferably 30 to 60°. When the spray direction angle of the aerosol is within the above range, excellent diffusion uniformity is achieved.

[0047] The type of creeping pest that the creeping pest control method of the present invention is effective against is not particularly limited. Examples of creeping pests include spiders, cockroaches, centipedes, ants, house centipedes, millipedes, pill bugs, woodlice, termites, caterpillars, mites, lice, ticks, and bedbugs. Among these, the method can exert an excellent control effect against spiders, cockroaches, and bedbugs, and particularly effective against bedbugs such as bedbugs (Cimex lectularius) and Taiwanese bedbugs (Nettites). [Example]

[0048] In order to verify the effectiveness of the present invention, aerosols for controlling crawling pests (Examples 1 to 17) having the characteristic configuration of the present invention were prepared, and the extermination effect on bed bugs that roam the floor and bed bugs that hide in gaps was examined. For comparison, aerosols for controlling crawling pests (Comparative Examples 1 to 8) not having the characteristic configuration of the present invention were prepared, and the same examination was carried out.

[0049] Example 1 An aerosol concentrate was prepared by dissolving 0.168 g (0.56 w / v%) of metofluthrin as compound A, a 2,3,5,6-tetrafluorobenzyl ester compound, and 13.20 g (44 w / v%) of fenothrin as compound B, a 3-phenoxybenzyl ester compound, in 13.76 g of ethanol as a solvent. This aerosol concentrate had a δ value of 0.948, calculated using the aforementioned formula (1). 30 mL of this aerosol concentrate and 70 mL of liquefied petroleum gas were pressurized and filled into an aerosol container equipped with a metered dose valve (spray volume per shot: 0.4 mL), to obtain the aerosol for controlling crawling pests used in Example 1. This aerosol for controlling crawling pests had a volume ratio [L / (L+G)] of 0.3, calculated from the fill volume L of the aerosol concentrate and the fill volume G of the propellant, and had a spray force of 14 gf at a spray distance of 5 cm.

[0050] Example 2 An aerosol concentrate was prepared by dissolving 0.168 g (0.56 w / v%) of metofluthrin as compound A, a 2,3,5,6-tetrafluorobenzyl ester compound, and 13.20 g (44 w / v%) of fenothrin as compound B, a 3-phenoxybenzyl ester compound, in 13.76 g of ethanol as a solvent. This aerosol concentrate had a δ value of 0.948, calculated using the aforementioned formula (1). 30 mL of this aerosol concentrate and 70 mL of liquefied petroleum gas were pressurized and filled into an aerosol container equipped with a metered injection valve (0.2 mL per injection), to obtain the aerosol for controlling crawling pests used in Example 2. This aerosol for controlling crawling pests had a volume ratio [L / (L+G)] of 0.3, calculated from the aerosol concentrate's fill volume L and the propellant's fill volume G, and had a spray force of 5 gf at a spray distance of 5 cm.

[0051] Example 3 An aerosol concentrate was prepared by dissolving 0.168 g (0.56 w / v%) of metofluthrin as compound A, a 2,3,5,6-tetrafluorobenzyl ester compound, and 13.20 g (44 w / v%) of fenothrin as compound B, a 3-phenoxybenzyl ester compound, in 13.76 g of ethanol as a solvent. This aerosol concentrate had a δ value of 0.948, calculated using the aforementioned formula (1). 30 mL of this aerosol concentrate and 70 mL of liquefied petroleum gas were pressurized and filled into an aerosol container equipped with a metered injection valve (spray volume per injection: 1.0 mL), to obtain the aerosol for controlling crawling pests used in Example 3. This aerosol for controlling crawling pests had a volume ratio [L / (L+G)] of 0.3, calculated from the fill volume L of the aerosol concentrate and the fill volume G of the propellant, and had a spray force of 27 gf at a spray distance of 5 cm.

[0052] [Examples 4 to 17, Comparative Examples 1 to 8] Various aerosols for controlling crawling pests were prepared using the formulations shown in Tables 1 and 2 according to the procedure of Example 1. Each aerosol for controlling crawling pests was prepared so that the spray force at a spray distance of 5 cm was 14 gf.

[0053] [Table 1]

[0054] [Table 2]

[0055] Tests were conducted to confirm (1) the extermination effect on bed bugs that roam the floor, and (2) the extermination effect on bed bugs that hide in crevices for Examples 1 to 17 and Comparative Examples 1 to 8. The test results are shown in Table 3.

[0056] (1) Effectiveness in eliminating bed bugs that roam the floor A total of four 20x20cm glass panels are enclosed, with a volume of 25m 3 room (equivalent to a 6-tatami room, area 10m 2) were placed at the four corners of a room. A plastic ring approximately 10 cm in diameter coated with Vaseline was placed on each glass plate to prevent escape, and five test insects (bed bugs) were released into each ring and allowed to roam freely. In Examples 1, 4-17, and Comparative Examples 1-8, 0.4 mL of the test aerosol was sprayed four times in the center of the room, directed slightly upward at the four corners. In Example 2, 0.2 mL of the test aerosol was sprayed six times in the center of the room, directed slightly upward at the four corners. In Example 3, 1.0 mL of the test aerosol was sprayed one time in the center of the room, directed slightly upward at an angle. After 24 hours of exposure to the insecticide, the glass plate and the ring containing the test insects were moved to another room, where they were fed. The mortality rate of the test insects was determined after another 24 hours.

[0057] (2) Effective against bed bugs hiding in crevices A closed tub (35cm wide, 28cm deep, 6cm high) coated with Vaseline to prevent escape has a volume of 25m 3 room (equivalent to a 6-tatami room, area 10m 2 ) were placed in the four corners of a room, and five bed bugs were released into each bat. A wooden shelter (20 cm wide, 10 cm deep, 1 cm high, open only at the front) was then placed in place to allow the bed bugs to hide. In Examples 1, 4 to 17, and Comparative Examples 1 to 8, 0.4 mL of the test aerosol was sprayed four times in the center of the room, slightly diagonally upward toward the four corners. In Example 2, 0.2 mL of the test aerosol was sprayed six times in the center of the room, slightly diagonally upward toward the four corners. In Example 3, 1.0 mL of the test aerosol was sprayed one time in the center of the room, slightly diagonally upward. After 30 minutes of spraying, the bats were left to be exposed to the insecticide, and the wooden shelters containing the test insects were moved to another room, where they were fed. Five days later, the mortality rate of the test insects was determined.

[0058] [Table 3]

[0059] As a result of the test, in all of Examples 1 to 17, the mortality rate of bed bugs crawling on floors was 85% or more, and the mortality rate of bed bugs hiding in crevices was 80% or more. This confirmed that by implementing the crawling pest control method of the present invention, it is possible to obtain high levels of control effectiveness against both bed bugs crawling on floors and bed bugs hiding in crevices. The crawling pest control aerosol used in Examples 1 and 4 to 17 was effective for approximately 60 treatments, assuming that 1.6 mL (0.4 mL x 4) was used per treatment. The crawling pest control aerosol used in Example 2 was effective for approximately 80 treatments, assuming that 1.2 mL (0.2 mL x 6) was used per treatment. The aerosol for controlling creeping pests used in Example 3 was effective for about 100 treatments, assuming that 1.0 mL was used per treatment.

[0060] In contrast, in the cases of Comparative Examples 1 and 2 in which the value of δ calculated by the above formula (1) was outside the range of 0.45 to 4.00, sufficient control effects were not obtained against both bed bugs that roam the floor and bed bugs that hide in crevices. From this, it is thought that when the value of δ is outside the range of 0.45 to 4.00, the synergistic effect of using in combination a 2,3,5,6-tetrafluorobenzyl ester compound, a 3-phenoxybenzyl ester compound, and a solvent that is a lower alcohol having 2 to 3 carbon atoms or a higher fatty acid ester having 16 to 20 carbon atoms is not fully exerted.

[0061] In Comparative Example 3, in which empenthrin, which is different from a 2,3,5,6-tetrafluorobenzyl ester compound, was used as compound A, the control effect against bed bugs hiding in crevices was particularly insufficient. In Comparative Example 4, in which imiprothrin, which is different from a 3-phenoxybenzyl ester compound, was used as compound B, almost no control effect was observed against either bed bugs crawling on the floor or bed bugs hiding in crevices. Furthermore, in Comparative Example 5, in which only a 3-phenoxybenzyl ester compound, compound B, was blended as the crawling pest control ingredient, the control effect against bed bugs hiding in crevices was particularly insufficient. In Comparative Example 6, in which only a 2,3,5,6-tetrafluorobenzyl ester compound, compound A, was blended as the crawling pest control ingredient, almost no control effect was observed against either bed bugs crawling on the floor or bed bugs hiding in crevices. From this, it is believed that in order to obtain sufficient control effects against both bed bugs that roam the floor and those that hide in crevices, it is effective to use multiple types of crawling pest control ingredients in combination, but simply using multiple types of crawling pest control ingredients in combination is not sufficient, and it is necessary to use a combination of the specific 2,3,5,6-tetrafluorobenzyl ester compound and 3-phenoxybenzyl ester compound specified in the present invention.

[0062] The volume ratio [L / (L+G)] calculated from the fill volume L of the aerosol concentrate and the fill volume G of the propellant was 0.6. Comparative Example 7, in which the fill volume of the aerosol concentrate was excessively large, exhibited a high control effect against bed bugs roaming the floor, but was insufficient in its control effect against bed bugs hiding in crevices. This is thought to be because the large fill volume of the aerosol concentrate resulted in large spray particles, which settled too quickly on the floor surface, preventing the spray particles from reaching the crevices insufficiently, resulting in a reduced control effect against bed bugs hiding in crevices. On the other hand, Comparative Example 8, in which the volume ratio [L / (L+G)] was 0.05 and the fill volume of the propellant was excessively large, exhibited a control effect against bed bugs hiding in crevices, but was insufficient in its control effect against bed bugs roaming the floor. This is thought to be because the spray particles are too small due to the large filling volume of the propellant, making it easier for them to reach gaps, but the spray particles that do not reach the gaps remain in the air for a long time without settling on the floor, resulting in a shortage of crawling pest control ingredients adhering to the floor surface.

[0063] [Reference example 1] To confirm the effect of using a solvent other than the solvents used in the examples (ethanol, 2-propanol, isopropyl myristate) in the aerosol for controlling crawling pests of the present invention, an aerosol for controlling crawling pests (Reference Example 1) was prepared by using Isopar M, an isoparaffinic solvent, instead of 2-propanol as the solvent in the formulation of Example 7. The aerosol for controlling crawling pests of Reference Example 1 had a δ value calculated by the above-mentioned formula (1) of 2.28, a volume ratio [L / (L+G)] calculated from the filling volume L of the aerosol concentrate and the filling volume G of the propellant of 0.3, and a spray force of 14 gf at a spray distance of 5 cm.

[0064] When the aerosol for controlling crawling pests of Reference Example 1 was subjected to a test for confirming the extermination effect in the same manner as in the above Examples, the mortality rate (after 1 day) of bed bugs crawling on the floor was 80%, but the mortality rate (after 5 days) of bed bugs hiding in crevices was only 15%, and the control effect against bed bugs hiding in crevices was lower than that against bed bugs crawling on the floor. This is thought to be because the spray particles did not reach the crevices sufficiently after spraying, and the control effect (synergistic effect) of the specific 2,3,5,6-tetrafluorobenzyl ester compound and the 3-phenoxybenzyl ester compound specified in the present invention against bed bugs hiding in crevices was not as strong as in the Examples.

[0065] (3) Spider extermination effect 1 A total of four 20x20cm glass plates (for the house spider) are enclosed, giving a volume of 25m 3 room (equivalent to a 6-tatami room, area 10m 2 ) were placed at the four corners of a room, and a plastic ring approximately 20 cm in diameter was placed on each glass plate. A designated test insect (Theridiidae: one spider) was released into each ring and allowed to roam freely. The crawling pest control aerosol of Example 9 was sprayed in the center of the room (1.5 m above the floor) at a rate of 0.4 mL each, with the direction slightly shifted upward. After 30 minutes of spraying, the test insects were exposed to the agent. After that, the glass plate and the ring containing the test insects were moved to another room, where they were fed. After a further 24 hours, the mortality rate of the test insects was determined; the mortality rate was 100%.

[0066] (4) Spider control effect 2 A total of four 20x20cm glass plates (for the house spider) are enclosed, giving a volume of 25m 3 room (equivalent to a 6-tatami room, area 10m 2) were placed at the four corners of a room, and a plastic ring approximately 20 cm in diameter was placed on each glass plate. A designated test insect (Theridiidae: one spider) was released into each ring and allowed to roam freely. The crawling pest control aerosol of Example 12 was sprayed in the center of the room (1.5 m above the floor) at a rate of 0.4 mL each, with the direction slightly shifted upward. After 30 minutes of spraying, the test insects were exposed to the agent. The glass plate, along with the ring containing the test insects, was then moved to another room, where they were fed. After a further 24 hours, the mortality rate of the test insects was determined; the mortality rate was 100%.

[0067] (5) Cockroach extermination effect 1 A total of four 20 x 20 cm glass plates (for American cockroaches) are enclosed to create a volume of 25 m 3 room (equivalent to a 6-tatami room, area 10m 2 ) were placed at the four corners of a room, and a plastic ring approximately 20 cm in diameter was placed on each glass plate. A designated test insect (American cockroach: five larvae) was released into each ring and allowed to roam freely. The crawling pest control aerosol of Example 9 was sprayed in the center of the room (1.5 m above the floor) at a rate of 0.4 mL each, with the direction slightly shifted upward. After 30 minutes of spraying, the test insects were exposed to the agent. The glass plate, along with the rings containing the test insects, was then moved to another room, where they were fed. After a further 24 hours, the mortality rate of the test insects was determined, which was 100%.

[0068] (6) Cockroach extermination effect 2 A total of four 20 x 20 cm glass plates (for American cockroaches) are enclosed to create a volume of 25 m 3 room (equivalent to a 6-tatami room, area 10m 2) were placed at the four corners of a room, and a plastic ring approximately 20 cm in diameter was placed on each glass plate. A designated test insect (American cockroach: five larvae) was released into each ring and allowed to roam freely. The crawling pest control aerosol of Example 12 was sprayed in the center of the room (1.5 m above the floor) at a rate of 0.4 mL each, with the direction slightly shifted upward. After 30 minutes of spraying, the test insects were exposed to the agent. The glass plate, along with the rings containing the test insects, was then moved to another room, where they were fed. After a further 24 hours, the mortality rate of the test insects was determined, which was 95%. [Industrial Applicability]

[0069] The method for controlling creeping pests and the aerosol for controlling creeping pests of the present invention can be used for the purpose of controlling creeping pests, particularly bedbugs, in ordinary houses, accommodation facilities, etc.

Claims

1. General formula (I): 【Chemistry 1】 [wherein X represents a hydrogen atom, a methyl group, or a methoxymethyl group; R １ and R ２ and each represent a hydrogen atom, a halogen atom, an alkyl group having 1 to 3 carbon atoms, a haloalkyl group having 1 to 3 carbon atoms, or a cyano group.], and a 2,3,5,6-tetrafluorobenzyl ester compound represented by the general formula (II): 【Chemistry 2】 [wherein Y represents a hydrogen atom or a cyano group, Z represents a hydrogen atom or a fluorine atom, and R 3 and R 4 and each represent a hydrogen atom, a halogen atom, an alkyl group having 1 to 3 carbon atoms, or a haloalkyl group having 1 to 3 carbon atoms.], and an aerosol concentrate containing a solvent and a propellant are filled into an aerosol container equipped with a metered dose injection valve, When the content by weight of the 2,3,5,6-tetrafluorobenzyl ester compound in the aerosol concentrate is a, the content by weight of the 3-phenoxybenzyl ester compound is b, and the content by weight of the solvent in the aerosol concentrate is c, the following formula (1) can be obtained: δ = b / (a+c)...(1) δ defined as follows is between 0.522 and 2.52; When the filling volume of the aerosol concentrate is L and the filling volume of the propellant is G, the following formula (2) is obtained: 0.1 ≦ L / (L+G) ≦ 0.5 (2) It is configured to satisfy The spray force at a spray distance of 5 cm is set to 10 to 50 gf. the 2,3,5,6-tetrafluorobenzyl ester compound is at least one selected from the group consisting of metofluthrin, transfluthrin, and profluthrin, the 3-phenoxybenzyl ester compound is at least one selected from the group consisting of fenothrin, permethrin, and cyphenothrin; the solvent is ethanol, The amount of the metered injection valve per injection is 0.2 to 1.0 mL; The aerosol for controlling creeping pests, wherein the creeping pests are bedbugs.

2. 2. The aerosol spray for controlling crawling pests according to claim 1, which is sprayed indoors into a space to control bedbugs hiding in gaps within the space.

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