Method and apparatus for generating real-time respiratory gate signals and detecting body deformation using an implanted fiber Bragg grating.

Abstract

To provide a method of correcting body deformation during image acquisition.SOLUTION: A garment for real time detection of body deformation during an image scan includes a front portion, made of a compression material and having a plurality of fiber Bragg gratings (FBGs). The garment includes a plurality of light emitters, each light emitter configured to pulse light waves through a corresponding FBGs and a plurality of light sensors, each light sensor attached to a corresponding FBG and configured to receive pulsed light waves. A processor obtains data through a data acquisition module configured to receive from the light sensors peak wavelengths reflected by the FBG based on the effective shifts of the Bragg wavelengths of the FBGs aligned along the cartesian coordinate system, the processor may correct acquired image data or re-direct an external beam treatment to compensate for body deformation during an image scan.SELECTED DRAWING: Figure 2A

Description

Technical Field

[0001] (Related Application) This application is a continuation application of U.S. Application No. 16 / 723,352, filed on December 20, 2019. The entire disclosure of the above application is incorporated herein by reference.

Background Art

[0002] Anatomical and functional imaging methods such as computed tomography (CT), magnetic resonance imaging (MRI), positron emission tomography and single photon emission computed tomography (PET and SPECT) are subject to image degradation due to the respiratory motion of patients. Also, in some cases of CT scans, patients are required to hold their breath during image acquisition, but this is not always practical because not all patients can hold their breath due to age and / or physical condition . In addition, breath-hold CT scans require the scan to be completed quickly, which is typically achieved only by rapidly moving the table, so they are typically scans with a higher radiation dose . In external beam (photon and particle) radiation therapy, in order to minimize the dose delivered to surrounding healthy tissues while delivering the maximum dose to the tumor, the intensity and / or range is adjusted and the beam is raster scanned across the tumor . Since internal organs, as well as tumors, move with the human body due to respiratory motion, the effectiveness of intensity or range-adjusted external beam therapy is highly dependent on respiratory motion correction.

[0003] Currently, mainly two types of respiratory motion management devices are used. One of them, the "Anzai" method, has a wearable with an electrical strain sensor attached near the patient's diaphragm​​​​ A belt is used. The disadvantage of this method is that the movement is measured in only one plane, and the image And because it distorts the treatment area due to its high attenuation characteristics, imaging scans or treatment procedures This includes the fact that the device cannot be in the field of view in between. The second class of method is, Light signals are reflected, motion signals are induced, or structured light is mapped onto the patient. Optical techniques (V) are used, which involve either a physical marker or reflector on the patient. Use arian RPM, C-Rad, and GateCT, etc. Disadvantages of this method In this case, light reflection may be significantly altered by objects in the pathway, including the patient's clothing or covers. This means that these methods are more difficult to perform with imaging than with treatment. It contains facts. [Overview of the Initiative]

[0004] Embodiments consistent with the principle of the present invention compensate for body deformation during image acquisition. Includes methods and systems for compensating. In one embodiment, body image data Once acquired, the system deploys multiple fiber Bragg grates placed on the body. Peak wavelength data is acquired from fiber Bragg grating (FBG), and FBG is located on the body. They are aligned along the Cartesian coordinate system. Via FBG, the system is the body during image acquisition. The system detects the effective shift of the Bragg wavelength of the FBG caused by deformation. Based on the effective shift of the Bragg wavelength of FBG aligned along the Cartesian coordinate system, the image To correct for body deformation during scanning, image data acquired during image reconstruction (image d Modify ata.

[0005] In some embodiments, the system uses computed tomography (CT) scans and magnetic resonance imaging. Image (MRI) scan, positron emission tomography (PET) scan, or single-photon emission Used in relation to data acquired through type 1 computed tomography (SPECT) scans. It can be used.

[0006] In other embodiments, the system moves the body through the cavity of the scanning device, and the body This may include acquiring volumetric image data for each slice. The system is placed on the body. Peak wavelength data is acquired from multiple fiber Bragg gratings (FBGs). The system detects the Bragg wavelength of FBG caused by body deformation during image acquisition. It detects the effective shift and, based on the effective shift of the Bragg wavelength in the FBG, it prevents the body from moving. Furthermore, to prevent image data from being acquired during body deformation, the scan device was passed through a cavity. To control the movement of the body.

[0007] Another embodiment consistent with the principles of the present invention is a photon beam used in connection with the treatment of tumors. Systems to correct physical deformities during external beam therapy, such as radiotherapy or proton therapy. Includes a system. In one embodiment, a target area of ​​the body for external beam therapy is identified. Tem receives multiple fiber Bragg gratings (FBGs) placed on the body. The system acquires wavelength data, and the FBGs are aligned along the Cartesian coordinate system. External beam therapy is directed to the target area. FBG caused by body deformation during treatment. When an effective shift in the Bragg wavelength is detected, external beam therapy maintains focus on the target region. To achieve this, based on the effective shift of the Bragg wavelength of FBG aligned along the Cartesian coordinate system. Subsequently, it may be redirected to correct body deformations during image scanning.

[0008] Clothing for real-time detection of body deformations during image scanning is made from a compression material and includes a front portion having a plurality of fiber Bragg gratings (FBGs). The front portion is disposed over the human body, and the FBGs are aligned along a Cartesian coordinate system. The clothing includes a plurality of light emitters, each configured to pulse light waves through a corresponding FBG and a plurality of light sensors. Each light sensor is attached to a corresponding FBG and is configured to receive the pulsed light waves. A processor acquires data through a data acquisition module configured to receive from the light sensors the peak wavelengths reflected by the FBGs. The processor may be embedded in the clothing or located in a remote device or terminal, and also includes a comparator configured to determine the effective shift of the Bragg wavelength due to axial strain on the FBG. n material), includes a front portion having a plurality of fiber Bragg gratings (FBGs), the front portion is disposed over the human body, and the FBGs are aligned along a Cartesian coordinate system. The clothing includes a plurality of light emitters, each configured to pulse light waves through a corresponding FBG and a plurality of light sensors. Each light sensor is attached to a corresponding FBG and is configured to receive the pulsed light waves. A processor acquires data through a data acquisition module configured to receive from the light sensors the peak wavelengths reflected by the FBGs. The processor may be embedded in the clothing or located in a remote device or terminal, and also includes a comparator configured to determine the effective shift of the Bragg wavelength due to axial strain on the FBG. The front portion is disposed over the human body, and the FBGs are aligned along a Cartesian coordinate system. The clothing includes a plurality of light emitters, each configured to pulse light waves through a corresponding FBG and a plurality of light sensors. Each light sensor is attached to a corresponding FBG and is configured to receive the pulsed light waves. A processor acquires data through a data acquisition module configured to receive from the light sensors the peak wavelengths reflected by the FBGs. The processor may be embedded in the clothing or located in a remote device or terminal, and also includes a comparator configured to determine the effective shift of the Bragg wavelength due to axial strain on the FBG. The clothing includes a plurality of light emitters, each configured to pulse light waves through a corresponding FBG and a plurality of light sensors. Each light sensor is attached to a corresponding FBG and is configured to receive the pulsed light waves. A processor acquires data through a data acquisition module configured to receive from the light sensors the peak wavelengths reflected by the FBGs. The processor may be embedded in the clothing or located in a remote device or terminal, and also includes a comparator configured to determine the effective shift of the Bragg wavelength due to axial strain on the FBG. Each light emitter is configured to pulse light waves through a corresponding FBG and a plurality of light sensors. Each light sensor is attached to a corresponding FBG and is configured to receive the pulsed light waves. A processor acquires data through a data acquisition module configured to receive from the light sensors the peak wavelengths reflected by the FBGs. The processor may be embedded in the clothing or located in a remote device or terminal, and also includes a comparator configured to determine the effective shift of the Bragg wavelength due to axial strain on the FBG. Each light sensor is attached to a corresponding FBG and is configured to receive the pulsed light waves. A processor acquires data through a data acquisition module configured to receive from the light sensors the peak wavelengths reflected by the FBGs. The processor may be embedded in the clothing or located in a remote device or terminal, and also includes a comparator configured to determine the effective shift of the Bragg wavelength due to axial strain on the FBG. A processor acquires data through a data acquisition module configured to receive from the light sensors the peak wavelengths reflected by the FBGs. The processor may be embedded in the clothing or located in a remote device or terminal, and also includes a comparator configured to determine the effective shift of the Bragg wavelength due to axial strain on the FBG. The processor may be embedded in the clothing or located in a remote device or terminal, and also includes a comparator configured to determine the effective shift of the Bragg wavelength due to axial strain on the FBG. However, it may be embedded in the clothing or located in a remote device or terminal, and also includes a comparator configured to determine the effective shift of the Bragg wavelength due to axial strain on the FBG. The processor also includes a comparator configured to determine the effective shift of the Bragg wavelength due to axial strain on the FBG.

[0009] The processor is configured to modify the acquired image data to correct body deformations during image scanning based on the effective shift of the Bragg wavelengths of the FBGs aligned along the Cartesian coordinate system, or is configured to redirect external beam therapy to correct body deformations during image scanning based on the effective shift of the Bragg wavelengths of the FBGs aligned along the Cartesian coordinate system to maintain focus on the target area. The processor may further include a modification module. Based on the effective shift of the Bragg wavelengths of the FBGs aligned along the Cartesian coordinate system, the processor is configured to modify the acquired image data to correct body deformations during image scanning. Or, based on the effective shift of the Bragg wavelengths of the FBGs aligned along the Cartesian coordinate system to maintain focus on the target area, the processor is configured to redirect external beam therapy to correct body deformations during image scanning. The processor may further include a modification module. Based on the effective shift of the Bragg wavelengths of the FBGs aligned along the Cartesian coordinate system, the processor is configured to redirect external beam therapy to correct body deformations during image scanning. The processor may further include a modification module configured to redirect external beam therapy to correct body deformations during image scanning based on the effective shift of the Bragg wavelengths of the FBGs aligned along the Cartesian coordinate system. The processor may further include a modification module. BRIEF DESCRIPTION OF THE DRAWINGS

[0010] As mentioned above, the same reference letters refer to the same part in the attached drawings. As will be apparent from the following more specific description of the exemplary embodiments, the drawings are The scale is not necessarily accurate; instead, the focus is on illustrating the embodiments.

[0011] [Figure 1] This figure shows a typical fiberglass core (FBG). [Figure 2A] This figure shows one embodiment of clothing that can be used during image scanning for real-time detection of body deformation according to the principles of the present invention. [Figure 2B] This figure shows another embodiment of clothing that can be used during image scanning for real-time detection of body deformation according to the principles of the present invention. [Figure 3] This figure shows yet another embodiment of clothing that can be used during image scanning for real-time detection of body deformation according to the principles of the present invention. [Figure 4] This figure shows an exemplary medical imaging system that may use embodiments consistent with the present invention. [Figure 5A] These are cross-sectional images that can be acquired by a medical imaging system. [Figure 5B] These are cross-sectional images that can be acquired by a medical imaging system. [Figure 6] This flowchart shows how to correct body deformation during image acquisition. [Figure 7] This figure shows an exemplary medical device for external beam therapy, which may use embodiments consistent with the present invention. [Figure 8] Figure 7 is a cross-sectional view of the body showing external beam therapy using the medical device. [Figure 9] This flowchart shows methods for correcting physical deformities during external beam therapy. [Figure 10] This figure shows an exemplary patient handling system, including embodiments consistent with the principles of the present invention. [Modes for carrying out the invention]

[0012] An exemplary embodiment is described below.

[0013] As shown in Figure 1, the fiber Bragg grating (FBG) 100 is refraction A small optical fiber with multiple reflection points 130a~n that generate periodic fluctuations in the rate This is bar 120. The FBG reflects a specific wavelength (λB) around a bandwidth ΔλB. The periodicity A of the grating is related to the Bragg wavelength λB.

number

[0014]

number

[0015] One or more FBs in wearable material that can enclose anatomically relevant parts of the human body. By implanting one or more optical fibers having G, physiological processes such as respiration It can be used to sense the deformation of that part resulting from the material. In a particular embodiment, the deformation data is caused by deformation during image acquisition. It can be used to correct constant strain. In other embodiments, deformation data is due to respiration. By modifying delivery to compensate for the movement induced by this, certain medical treatments It can be used to support targeted releases.

[0016] Before using embedded FBGs as strain gauges, load the response function and linearity of the FBGs. It needs to be characterized as a function of FBG. Therefore, using an electrical strain gauge, the applied tensile load is measured in Cartesian terms for a three-dimensional object. The FBG can be calibrated to approximate the displacement readings of the body within the coordinate system. For BG to function as a reliable strain gauge, when FBG is stretched under tensile load... The change in the reflected wavelength must linearly track the electrical strain gauge data. When calibrated, the FBG response uses embedded strain gauges to detect surface deformation of an object. It can be used with confidence as a gauge. This is also true within reasonable limits of the gauge's elasticity, for objects. It can be used to detect the degree of surface displacement. Pressure is compared to strain or wavelength. Based on the calibration curve, the degree of displacement is detected along with strain data from the sensor. It is possible.

[0017] Figures 2A and 2B illustrate the principle of the present invention for real-time detection of body deformation. These are embodiments of garments 200 and 250 that can be used during image scanning. In garment 200, Multiple FBG fibers 210a~n are embedded laterally along the garment, It extends in a direction parallel to the canvas plane A. In garment 250, there are multiple FBG fibers 210a ~n is embedded vertically along the clothing and extends perpendicular to the scanning plane A. In both embodiments, garments 200 and 250 pass through FBG fibers 210a-n. Each FBG 210a~ may have an input 220 of a laser or light source that is transmitted. n is connected to a light sensor (not shown) that receives pulsed light waves from a light source. In addition Clothing 200 and 250 may also include output 230, and the light sensor is used for light transmission. The data related to this was passed through FBG 210a to n, and the refraction of FBG 210a to n was measured. An external processor that can identify rate shifts and suggest deformation of the surface of an object within the clothing. It may also be provided to. In other embodiments, the processor is located inside the garment and also WiFi or It may transmit data via wireless transmission such as Bluetooth. Multiple FBG 210a~n each provide a different major axis marker along the Cartesian coordinate system. Therefore, it can be helpful in identifying where a particular movement is occurring in the cross-sectional scanning plane. Given its low attenuation characteristics, it can be used both during imaging and during treatment.

[0018] In addition, the wavelengths measured over time for free-breathing patients wearing these garments The changes represent patient-specific respiratory signals. Respiratory signals are measured today using Anzai belts and RPM. Breathing gates for devices, etc. Used as a gate signal for imaging and therapy, in a manner similar to that used in the device. Yes. In this case, the additional benefit is that the gating device does not induce imaging artifacts or therapeutic interference. It means being able to be within the imaging or therapeutic field without being guided.

[0019] Figure 3 shows the principle of the present invention for real-time detection of body deformation during image scanning. Another embodiment of the garment 300 that can be used. In this garment, multiple FBG fibers 310a~n are embedded along the long axis of the garment and are connected to multiple other FBG fibers. -350a~n are embedded horizontally along the garment. In addition, garment 300 is Furthermore, it may include output 330, and the light sensor provides data related to light transmission to FBG 310. Through a~n and FBG 350a~n respectively, FBG 310a~n and F Identifying the refractive index shift of BG 350a~n suggests deformation of the surface of an object within the clothing. It may be provided to an external processor capable of doing so. In another embodiment, the processor is a garment It is located inside and transmits data via wireless transmission such as WiFi or Bluetooth. It is also possible to have multiple F FBGs 210a~n similar to those of garments 200 and 250. BG 310a~n each provides different major axis markers along the Cartesian coordinate system. Therefore, it can be useful in identifying where a particular movement is occurring in the cross-sectional scanning plane. FB The addition of G 350a~n provides additional data sensitive to the movement of objects within clothing in different planes. It provides data and gives more accurate information about the location and intensity of the movement.

[0020] Clothing with an embedded FBG for real-time measurement of patient body deformation under respiratory conditions In the implementation method, a predetermined coordinate system such as the Cartesian coordinate system or the polar coordinate system is used, and several FBGs can be embedded. In addition, a given coordinate system can also use the minimum number of embedded FBGs. While using this method, the number of embedded FBGs is minimized while maximizing the fidelity of the measured deformation map. This may be decided to balance the competing interests of using it. The FBG is aligned with the patient's body along the coordinate system, or otherwise, the patient This means that it can be positioned for pseudo-random sampling of the body. In some embodiments This is because the accumulation of embedded FBGs aligns in a higher density distribution within one region, and other regions This means that FBGs can be distributed in a scattered manner within that region. Depending on the nature of the garment, a belt or shirt will fit around the body differently than a blanket. Because it may contain multiple FBGs, the distribution of FBGs within clothing can change. In addition, multiple FBGs These can be engraved inside a single-mode optical fiber, and they are at a predetermined optimal distance from one another. They are far apart, and each of these FBGs has a unique and distinct Bragg wavelength, Using a single optical fiber, a single broadband light source and a single wavelength division multiplexing detection system can be used. The stem can be used to measure the strain along its length. It has clear advantages over electrical strain gauge-based systems, but the latter is This is because each strain gauge requires its own electrical connection.

[0021] Figure 4 shows an exemplary medical imaging system 400 that may use embodiments consistent with the present invention. The system 400 includes an X-ray control device 411 and a system supplied from the X-ray control device 411. A high-voltage generator 413 for generating high voltage according to a Shot signal, and a subject placed on it. With E in place, a table 412 that can be displaced in the direction indicated by arrow L, and high-voltage In order to apply X-rays (photons) to subject E according to the high voltage supplied from the pressure generator 13 The X-ray source 414 and the X-ray detector 416 for detecting photons that have passed through subject E, and X-ray Data for collecting subject transmission data based on photons detected by detector 416 The data acquisition device 418 and the subject transmission data collected by the data acquisition device 418 Computed tomography includes an image reconstruction apparatus 420 for reconstructing the tomographic image of test subject E. It can be used as a layered imaging scanner. The X-ray source 414 and X-ray detector 416 are indicated by arrow A. It is rotatable in the direction. The above-mentioned components constitute a CT (computed tomography) scanner. The X-ray source 414 and X-ray detector 416 rotate around the subject E, creating an image. The image data provides cross-sectional image scans or "slice" images. The subject is positioned along the L-direction. As the device passes through the stem, multiple image "slices" are captured, providing a volumetric scan of the subject. The system displays the reconstructed tomographic images on a CRT (cathode ray tube) or similar device. The system may further include an image display device 422 for displaying images.

[0022] In a typical system, the rotation of the CT scanner 400 should not be too slow. The movement of Bull 412 must not be too slow, otherwise the respiratory movements during scanning will be affected. Image arches appear in body scans (e.g., abdominal or thoracic) and are reconstructed into CT volumes. It brings about image artifacts. Scanner 400 rotation speed and table 41 As the translational speed increases, in order to obtain appropriate data for sufficient image resolution, The intensity of X-ray source 414 must be higher. However, photons and atoms in biological tissue and Collisions with molecules can cause serious tissue damage. Measured as a bundle, X The more photons that arrive from source 414 per second, the greater the likelihood of tissue damage.

[0023] Some embodiments consistent with the principles of the present invention are embedded for real-time detection of respiratory movement. This includes devices such as wearable clothing having an integrated FBG. In one embodiment, the device collects data acquired at various stages of the respiratory cycle, and By separating the physical condition at that stage, the movement of the CT scanner and X-rays It may also be used as a breathing gate device that simultaneously controls the dose, thereby enabling breath-holding. The need for averaging over the respiratory cycle is reduced. The device detects respiratory movement. The CT scanner then pauses its operation and resumes when the body returns to its initial breathing state. Therefore, if the patient can be scanned together with the respiratory gate device, the X-ray dose to the patient is low. It can be done.

[0024] In other embodiments, deformation data is used for image reconstruction to correct deformation, and image data is used. However, so that it can be acquired without interruption or pause, the wearable clothing device is designed to allow voice The system may be configured to continuously detect the degree of deformation resulting from inhalation and respiratory displacement. .

[0025] In yet another embodiment, as shown in Figure 10, the patient handling system 1000 is, Pads having fibers containing embedded FBG, such as the garments shown in 2A, 2B, and 3. It may include 1080. As shown in Figure 10, multiple FBG fibers 1010a~n It is embedded along the long axis of the pad 1080, and another multiple FBG fiber 1050a-n are embedded horizontally along the pad. Consistent with the teachings of this specification. In an alternative embodiment, data related to body movement or displacement on the pad is provided. Therefore, the pad 1080 may have FBG embedded in other configurations. Furthermore, the patient handling systems (patient beds) for medical imaging and radiotherapy equipment are also used. It can be directly embedded. Similar to the garments shown in Figures 2A, 2B, and 3, the pad is output (illustrated) It may include (and the optical sensor may provide data to an external processor. FBG is , bed deflection under patient-specific loads, and respiratory signals from the patient in contact with the bed. They can be used to obtain both. Both of these parameters optimize patient image acquisition. It can be used for this purpose and for delivering treatment to patients.

[0026] Figure 5A is a cross-sectional image 500A of subject E that can be acquired by a medical imaging system. Figure 5B shows the effects of respiratory movement (e.g., expansion of body cavities during inhalation) on subject E. Cross-sectional image 500B is shown. Scanners such as the CT scanner 400 in Figure 4 use multiple image slides. To photograph the chair, deformation can cause deformation during volumetric scanning. Figure 5A, image 500A. In this case, the height of the cross-section of subject E's body is X1. In image 500B of Figure 5B, inspiration Therefore, the height of the cross-section of subject E's body is slightly higher, X2. CT scanner 400 Therefore, multiple slices are taken along the subject E and along direction L, between slices (for example) The sudden movement of 500A and 500B) causes significant fluctuations, which are within the Cartesian plane. This results in a distorted volumetric image. In both cross-sectional images 500A and 500B, the mass M It may be located within the scan, and its relative position within the volumetric scan can be detected.

[0027] Referring again to Figure 4, Subject E is wearing clothing 450 consistent with the principle of the present invention. This may also be done. Such garments 450 may have FBGs embedded within the garments 450 (not shown in Figure 4). Subject E may be communicating with the optical emitter 460 that transmits light through the scanner. As 400 passes along the L direction, the process including the data acquisition module 472 SA470 receives data from an optical sensor (not shown in Figure 4) attached to the FBG. The comparator 475 of the processor 470, due to the axial strain on the FBG, This allows us to identify the effective shift in refractive index and suggest deformation of the surface of an object within the clothing. When deformation is detected, the processor 470 sends deformation correction information to the image reconstruction module 4 It can be transmitted to 20 to enable image correction for arbitrary motion. In other embodiments, FB The processor 470, which includes a G data acquisition module 472 and a comparator 475, The data acquisition device 418 and the image reconstruction device 420 may be included in the same apparatus.

[0028] Figure 6 is a flowchart showing a method for correcting body deformation during image acquisition of subjects. Once the subject's image data is acquired in step 610, multiple images placed on the subject's body are taken. From the fiber Bragg grating (FBG), the peak wavelength data is obtained in step 62. It is acquired as 0. The Bragg wavelength of FBG caused by body deformation during image acquisition. An effective shift is detected in step 630. If a shift is detected, the Cartesian coordinate system is used. Based on the effective shift of the Bragg wavelength of the FBG aligned along the line, the body during image scanning To correct the deformation, the acquired image data is modified in step 640 during image reconstruction. It will be done.

[0029] Another embodiment consistent with the principles of the present invention involves embedding for real-time detection of respiratory movement. Devices such as wearable clothing with integrated FBGs are used for targeting, such as in external beam radiotherapy. To support automated delivery, body movements (for example, movements induced by breathing, etc.) It may also be used to detect muscle spasms. By detecting body movements, The therapy adjusts positioning to deliver the maximum dose to the tumor and the minimum dose to the surrounding healthy tissue. It can be delivered.

[0030] Figure 7 shows an exemplary medical device for external beam therapy that may use embodiments consistent with the present invention. Medical equipment 700. Medical linear accelerator (LINAC) is used for external beam radiation to cancer patients. It is a device commonly used for radiation therapy. Linear accelerators typically use high radio frequencies. Using radio frequency (RF) electromagnetic waves, a tube-like structure called an accelerator waveguide (not shown in Figure 7) is created. A gantry that accelerates charged particles (i.e., electrons) to high energies along a straight path inside the structure. Includes 710. In alternative embodiments, the medical device may include multiple emitters. The Ta715 emits high-energy X-rays (725) from the machine, directed at the patient's tumor. The patient lies on a movable treatment table 712. The patient is positioned, and these positions are It may be monitored using laser or mechanical means (not shown in Figure 7). Treatment table The L moves in and out of the gantry in direction L. In some alternative medical devices, the table Also, the patient is positioned from left to right (perpendicular to direction L) and / or up and down (emitter 715 or It can be moved (closer or further away). The gantry can rotate around the patient. Often, in radiation therapy, the gantry is rotated to move the treatment couch. This allows the substance to be delivered to the tumor within the patient from multiple angles.

[0031] Figure 8 is a cross-sectional view of patient P (Figure 800) showing external beam therapy using a medical device (Figure 7). This shows the emitter at various positions 810a~e as it rotates around patient P. First position In 810a, emitter 810 transmits to mass M through the patient, and in this radiotherapy, there is no such thing as The beam treatment is oriented in that form. As the gantry rotates through the second position 810b The beam continues to pass through the patient from different angles, but it continues to target mass M. The treatment passes through healthy tissue, but because the emitter continues to rotate, radiation to the healthy tissue is affected. Exposure is minimized. In accordance with the principle of the present invention, patient P has an FBG implanted in his clothing. Clothing 880, including (not shown in Figure 8), may be worn. (Regarding Figures 2 and 3) As mentioned above, these garments 880 are transmitted through FBG embedded within the garment 880. It may also be communicating with an optical emitter that transmits light (not shown in Figure 8). Patient P is medical After passing through the medical device and receiving treatment, the data acquisition module, as described in relation to Figure 4, is included. A processor similar to the one described above receives data from an optical sensor attached to the FBG. The effective shift in the refractive index of the FBG due to axial strain on the FBG is the change in the surface of the object inside the clothing. This suggests a specific shape, allowing for better targeting of mass M and minimizing dose to non-target tissues. This allows medical devices to shift the positioning of the patient or emitter.

[0032] Figure 9 is a flowchart showing methods for correcting body deformation during external beam therapy. When the medical device identifies a target area of ​​the body for external beam therapy with the TEP910, the subject From multiple fiber Bragg gratings (FBGs) placed on the person's body, Wavelength data is acquired in step 920. In step 930, external beam therapy is targeted. It is directed towards the region. The Bragg wavelength of FBG caused by physical deformation during treatment The effective shift is detected in step 940. In step 950, any shift is detected. Then, in order to maintain focus on the target region, the FBG is aligned along the Cartesian coordinate system. Based on the effective shift of the vignetting wavelength, an external beam is used to correct for body deformation during image scanning. The treatment may be shifted. The patient's relative position to the gantry emitter during radiation therapy. Alternatively, it can be adjusted by moving one of the positions of the treatment table.

[0033] The low attenuation characteristics of garments with embedded FBGs allow for little to no interference. This will enable the provision of more accurate medical imaging and radiotherapy. In addition, it will improve the patient's comfort. It can also improve suitability and reduce radiation dose. These devices can also image body deformation. Because it is done as a function, it opens up the possibility of creating a new class of low-cost scanners, Making these imaging diagnostic methods more widely accessible to the most cost-sensitive populations is important. can.

[0034] Exemplary embodiments have been shown and described in particular, but do not deviate from the scope of the attached claims. Those skilled in the art will understand that various changes in form and detail can be made therein without any exception. It will probably happen.

[0035] It should be understood that the exemplary embodiments described above can be implemented in many different ways. Yes. In some embodiments, the various methods and machines described herein include a central processor. Memory, disk or other mass storage device, communication interface(s), input / A physical, virtual, or otherwise equipped output (I / O) device(s) and other peripherals. Alternatively, these may be implemented by hybrid general-purpose computers. For example, a data processor loads software instructions into the data processor, and then executes the instructions. The above method is performed by ensuring that the functions described herein are executed. It is converted into a machine.

[0036] As is well known in the art, such computers may include a system bus, In this context, the bus is used for data transfer between components of a computer or processing system. It is a complete hardware line. A bus is a different computer system. Elements, for example, processor, disk storage, memory, input / output ports, network Essentially, it's a shared conduit that connects things like network ports, and this is how information is transferred between elements. This enables one or more central processor units to be mounted on the system bus. It provides the execution of computer commands. The system bus also typically handles various inputs and and output devices, such as keyboards, mice, displays, printers, speakers, etc. An I / O device interface for connecting it to a computer is installed. A network interface is a computer that connects to a network. It enables connection to various other devices. The memory is used for the implementation of the embodiment. It provides volatile storage for computer software instructions and data. Disks or other mass storage devices can perform, for example, the various procedures described herein. Non-volatile computer software instructions and data used for implementation. Provide storage.

[0037] Therefore, embodiments typically include hardware, firmware, software, and Or they may be carried out in any combination thereof.

[0038] In certain embodiments, the procedures, apparatus and processes described herein are non-transient. Computer-readable media, for example, software instructions for systems. It also provides one or more DVD-ROMs, CD-ROMs, diskettes, tapes, etc. This constitutes a computer program product that includes any removable storage medium. Computer program products install any suitable software known in the art. It can be installed by a manual procedure. In another embodiment, software instructions At least a portion of it is downloaded via cable, communication, and / or wireless connection. It's okay.

[0039] Furthermore, firmware, software, routines, or instructions are used in the data processor. It may be described herein as performing specific actions and / or functions of However, naturally, such descriptions in this specification are merely for convenience, and The operation described is actually performed by the computing device, processor, controller, or file These are derived from other devices that execute homeware, software, routines, instructions, etc.

[0040] Naturally, flow diagrams, block diagrams, and network diagrams are more or It may contain fewer elements, be arranged in a different way, or be represented in a different way. That's good. However, certain implementations use block diagrams and network diagrams, as well as block diagrams and The number of network diagrams may affect the implementation of the embodiment, and the execution of the embodiment may be implemented in a specific way. This should be understood more clearly.

[0041] Therefore, further embodiments also include various computer architectures, physical Computers, virtual computers, cloud computers, and / or several of them It may be implemented in several combinations, and therefore the data processor described herein These are illustrative examples only and do not limit the embodiments.

[0042] The present invention has been particularly shown and described with reference to its exemplary embodiments, but the present invention is also described in part. Various modifications in form and detail may be made therein without departing from the scope of the attached claims. This will be understood by those skilled in the art.

Claims

1. A method for correcting body movements during image scanning, The steps include: acquiring wavelength data from multiple fiber Bragg gratings (FBGs) placed on the body using a processor; The processor detects an effective shift of the Bragg wavelength in the wavelength data caused by the movement of the body during image acquisition. The step of sending an instruction from the processor to the scanning device, wherein the instruction is: (i) the relative movement between the body and the scanning device during the image scan, (ii) Acquisition of image data while the body is moving, The steps include sending an instruction that controls each of the above in coordination based on the effective shift of the Bragg wavelength of the FBG, A method comprising the step of modifying the acquired image data during image reconstruction in the processor in order to correct the body movement based on the effective shift of the Bragg wavelength of the FBG.

2. The method according to claim 1, wherein the image data is obtained from a computed tomography (CT) scan, a magnetic resonance imaging (MRI) scan, a positron emission tomography (PET) scan, or a single-photon emission computed tomography (SPECT) scan.

3. The method according to claim 1, further comprising the step of arranging a single-mode optical fiber on the body, wherein the single-mode optical fiber includes the FBG.

4. The method according to claim 1, wherein the FBG is aligned along a Cartesian coordinate system.

5. The method according to claim 4, wherein the effective shift of the Bragg wavelength with respect to the FBG measures strain along at least one axis of the Cartesian coordinate system.

6. The method according to claim 1, wherein the step of sending the command to control the acquisition of the image data includes the step of sending a command to acquire image data of a target region while correcting the relative movement between the body and the scanning device.

7. The steps include identifying an object for external beam therapy in the target region, The method according to claim 6, further comprising the step of estimating the motion of the object by correlating the acquired image data with the effective shift of the Bragg wavelength in the wavelength data.

8. The method according to claim 7, further comprising the step of sending a command from the processor to control the external beam therapy device based on at least a portion of the estimated motion in order to maintain focus on the target region during the external beam therapy.

9. A wearable device for real-time detection of body movement during image scanning, A front section having multiple fiber Bragg gratings (FBGs) aligned along a coordinate system, An optical emitter configured to emit light wave pulses through the aforementioned FBG, A light sensor configured to receive pulsed light waves, It is a processor, A data acquisition module configured to receive the Bragg wavelength reflected by the FBG from the optical sensor, A comparator configured to determine the effective shift of the Bragg wavelength by the strain along the FBG, A controller configured to define instructions, wherein the instructions are (i) relative movement between the body and the scanning device during image scanning, (ii) Acquisition of image data while the body is moving, A wearable device comprising a processor including a controller, which is a controller that provides instructions for controlling each of the Bragg wavelengths in coordination based on the effective shift of the FBG.

10. The wearable device according to claim 9, wherein the coordinate system is a Cartesian coordinate system.

11. The wearable device according to claim 10, wherein the FBG is aligned along the Cartesian coordinate system and measures strain along at least one axis.

12. The wearable device according to claim 9, further comprising a correction module configured to modify acquired image data to correct body movement during the image scan based on the effective shift of the Bragg wavelength of the FBG.

13. The wearable device according to claim 9, wherein the processor further includes an image acquisition module configured to acquire the image data from the scanning device, and the scanning device is a device that performs computed tomography (CT) scans, magnetic resonance imaging (MRI) scans, positron emission tomography (PET) scans, or single-photon emission computed tomography (SPECT) scans.

14. A method for correcting body movements during external beam therapy, The process involves a processor acquiring wavelength data from multiple fiber Bragg gratings (FBGs) placed on the body, and The steps include: detecting the effective shift of the Bragg wavelength of the FBG caused by body movement using a processor; The step of sending an instruction from the processor to the scanning device, wherein the instruction is: (i) relative movement between the body and the scanning device during image scanning, (ii) Acquisition of image data while the body is moving, The steps include sending a command, which is a command for controlling each of the Bragg wavelengths in coordination based on the effective shift of the FBG, A method comprising the step of sending a command from the processor to control the external beam therapy apparatus in order to compensate for the movement of the body based on the effective shift of the Bragg wavelength of the FBG during external beam therapy, thereby maintaining focus on a target region of the body receiving the external beam therapy.

15. The method according to claim 14, wherein the external beam therapy apparatus is an external beam radiotherapy apparatus or a proton beam therapy apparatus.

16. The method according to claim 14, wherein the effective shift of the Bragg wavelength with respect to the FBG measures strain along at least one axis of a Cartesian coordinate system.

17. The method according to claim 14, further comprising the step of sending a command from the processor to control the scanning device to acquire image data of the target region while correcting the movement of the body based on the effective shift of the Bragg wavelength.

18. The process involves the processor identifying an object located within the target region that is to be treated with the external beam therapy. The method according to claim 17, further comprising the step of estimating the motion of the object by correlating the acquired data with the effective shift of the Bragg wavelength in the wavelength data.

19. The method according to claim 18, wherein the sending step of sending a command to control the external beam therapy device in order to correct the movement of the body includes a command to control the external beam therapy device based on at least a portion of the estimated movement of the object.

20. A wearable device for real-time detection of body movement during external beam therapy, A front section having multiple fiber Bragg gratings (FBGs) aligned along a coordinate system, An optical emitter configured to emit light wave pulses through the aforementioned FBG, A light sensor configured to receive pulsed light waves, It is a processor, A data acquisition module configured to receive wavelengths reflected by the FBG from the optical sensor, A comparator configured to determine the effective shift of the Bragg wavelength by the strain along the FBG, A controller configured to define instructions, wherein the instructions are (i) relative movement between the body and the scanning device during image scanning, (ii) The external beam therapy device while the body is moving, A wearable device comprising a processor including a controller, which is a controller that provides instructions for controlling each of the Bragg wavelengths in coordination based on the effective shift of the FBG.

21. The wearable device according to claim 20, wherein the coordinate system is a Cartesian coordinate system.

22. The wearable device according to claim 21, wherein the FBG is aligned along the Cartesian coordinate system and measures strain along at least one axis.

23. The wearable device according to claim 20, wherein the external beam therapy device is an external photon beam radiotherapy device or a proton beam therapy device.

24. The wearable device according to claim 20, wherein the processor further includes an image acquisition module configured to acquire image data from a scanning device, and the scanning device is a device that performs computed tomography (CT) scans, magnetic resonance imaging (MRI) scans, positron emission tomography (PET) scans, or single-photon emission computed tomography (SPECT) scans.

25. The wearable device according to claim 20, further comprising a modification module configured to define commands for controlling the external beam therapy device to correct body deformation based on the effective shift of the Bragg wavelength of the FBG, thereby maintaining focus on a target region of the body.

26. A system for real-time detection of body movement during image scanning, A single-mode optical fiber having multiple fiber Bragg gratings (FBGs) aligned along a coordinate system, An optical emitter configured to pulse light waves through the first end of the single-mode optical fiber, An optical sensor attached to the single-mode optical fiber and configured to receive pulsed light waves through the plurality of FBGs, A computing device comprising at least one processor, wherein the processor is A data acquisition module configured to receive wavelength data from the optical sensor, A comparator configured to determine the effective shift of the Bragg wavelength in the wavelength data based on the strain along the FBG, A controller configured to define instructions, wherein the instructions are (i) relative movement between the body and the scanning device during image scanning, (ii) Acquisition of image data while the body is moving, A system comprising a computing device including a controller, which is a controller for controlling each of the Bragg wavelengths in coordination based on the effective shift of the FBG.

27. The system according to claim 26, further comprising a correction module configured to modify image data acquired from the scanning device to correct body movement during the image scan based on the effective shift of the Bragg wavelength of the FBG.

28. The system according to claim 26, wherein the processor further includes an image acquisition module configured to acquire image data acquired from the scanning device, and the scanning device is a device that performs computed tomography (CT) scans, magnetic resonance imaging (MRI) scans, positron emission tomography (PET) scans, or single-photon emission computed tomography (SPECT).

29. The system according to claim 26, wherein the coordinate system is a Cartesian coordinate system.

30. The method according to claim 29, wherein the FBG measures strain along at least one axis of the Cartesian coordinate system.

31. A system for real-time detection of body movement during external beam therapy, A single-mode optical fiber having multiple fiber Bragg gratings (FBGs) aligned along a coordinate system, An optical emitter configured to pulse light waves through the first end of the single-mode optical fiber, An optical sensor attached to the single-mode optical fiber and configured to receive pulsed light waves through the plurality of FBGs, A computing device comprising at least one processor, wherein the processor is A data acquisition module configured to receive wavelength data from the optical sensor, A comparator configured to determine the effective shift of the Bragg wavelength in the wavelength data based on the strain along the FBG, A controller configured to define instructions, wherein the instructions are (i) relative movement between the body and the scanning device during image scanning, (ii) The external beam therapy device while the body is moving, A system comprising a computing device, including a controller, which is a set of commands for controlling the other devices in coordination.

32. The system according to claim 31, further comprising a modification module configured to define commands for controlling the external beam therapy device to compensate for body movement based on the effective shift of the Bragg wavelength of the FBG, thereby maintaining focus on a target region.

33. The system according to claim 31, wherein the processor further includes an image acquisition module configured to acquire image data acquired from the scanning device, and the scanning device is a device that performs computed tomography (CT) scans, magnetic resonance imaging (MRI) scans, positron emission tomography (PET) scans, or single-photon emission computed tomography (SPECT) scans.

34. The system according to claim 31, wherein the coordinate system is a Cartesian coordinate system.

35. The system according to claim 34, wherein the FBG measures strain along at least one axis of the Cartesian coordinate system.

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