ANALYTICAL SYSTEM AND METHOD FOR DETERMINING HEMOGLOBIN PARAMETERS IN TOTAL BLOOD.

Abstract

A system (10) and method for measuring hemoglobin and bilirubin parameters in a whole blood sample using optical absorbance. The system (10) includes an optical sample module (20), a spectrometer module (100), an optical fiber assembly (90) optically connecting the optical sample module (20) to the spectrometer module (100), and a processor module (150). The optical sample module (20) has a light-emitting module (22) with an LED light source (28), a cuvette assembly (40), and a calibration light module (60). The processor module (150) receives and processes an electrical signal from the spectrometer module (100) and transforms the electrical signal into an output signal usable for displaying and reporting hemoglobin and / or total bilirubin parameter values ​​for the whole blood sample.

Claims

1. An optical component assembly (120) for use in a spectrometer module (100) of a system for measuring whole blood hemoglobin parameters or whole blood bilirubin parameters, wherein the system includes an optical path (21), the optical component assembly (120) comprising: a light-scattering element (130); and an achromatic lens assembly (121) disposed between the light-scattering element (130) and a light inlet port (109) of the spectrometer module (100), wherein the achromatic lens assembly (121) comprises: a fixed mounting end (122a); and a lens mount (122) with a lens mounting groove (122c) that is thermally compensated by permitting thermal expansion and contraction of the achromatic lens assembly (121) in a linear direction along the lens mounting groove (122c) toward or away from the fixed mounting end (122a);wherein the linear direction is also transverse to a beam of light from the light inlet port (109); and wherein the beam of light travels through the achromatic lens assembly (121) to the light dispersion element (130) and then back through the achromatic lens assembly (121).; 2. The optical component group (120) according to claim 1, wherein the light dispersion element (130) is a grating or a Littrow prism.

3. The optical component assembly (120) according to claim 1, wherein the fixed mounting end (122a) is permanently connected to a spectrometer base (104) or base plate (104a) and a non-fixed mounting end (122b) permits thermal expansion and contraction of the lens mount (122) in the linear direction toward or away from the fixed mounting end (122a). bQQonn / eznz / e / Yi 4. The optical component group (120) according to claim 3, wherein the achromatic lens assembly (121) includes an achromatic lens (124) fixedly attached to the lens mount (122).

5. The optical component group (120) according to claim 4, wherein the achromatic lens (124) is a spherical achromatic lens.

6. The optical component group (120) according to claim 3, wherein the unfixed mounting end (122b) has a fastener (126) extending through the lens mounting slot (122c).

7. The optical component group (120) according to claim 6, wherein the fastener (126) has a head, wherein the head (126a) of the fastener is spaced from the lens mounting slot (122c).

8. The optical component group (120) according to claim 3, wherein the lens mount (122) has an expansion coefficient that is greater than the expansion coefficient of the spectrometer base (104) or base plate (104a).

9. The optical component group (120) according to claim 7 further comprising a clamping spring (128) arranged between the head (126a) of the clamp (126) and the lens assembly (122).

Images