Inertial interfacial manipulation method and geometries

Abstract

The invention provides a system (1) for fluid manipulation, wherein the system (1) comprises a first liquid supply (10), a second liquid supply (20), a microfiuidic device (100), a cavitation induction system (200), and a control system (300), Wherein: the first liquid supply (10) is configured to provide a first liquid (15) to the microfiuidic device (100), the second liquid supply (20) is configured to provide a second liquid (25) to the microfiuidic 10 device (100), the microfluidic device (100) comprises a hosting chamber (110), wherein the hosting chamber (110) has a chamber length (L) defined by a first chamber end (111) and a second chamber end (112), Wherein the hosting chamber (110) has an average equivalent circular diameter (D) perpendicular to the length (L), Wherein L Z 3 >“D, Wherein the cavitation induction system (200) is selected from the group comprising a laser-based heating system, an 15 electric discharge system, and a heater, and wherein the control system (300) is configured to control the first liquid supply (10), the second liquid supply (20), and the heating system (200), and wherein the control system (300) has an operational mode wherein: in a preparation stage the first liquid supply (10) and the second liquid supply (20) are configured to provide a liquid multilayer (400) in the hosting chamber (110), wherein the liquid multilayer (400) comprises 11 layers (450) sequentially arranged along the chamber length (L), wherein n Z 2, wherein adjacent layers (450) are distinct phases, and wherein the layers (450) comprise a first liquid layer (415) comprising the first liquid (15) arranged adjacent to a second liquid layer (425) comprising the second liquid (25), and in a cavitation stage the cavitation induction system (200) is configured to induce cavitation of the first liquid (15) at a first location (41), wherein 25 the first location (41) is arranged in the first liquid layer (415).