Compositions incorporating (-)-hydroxycitric acid, chromium, and gymnemic acid, and related methods for promoting healthy body weight and improving related health factors

Abstract

Methods for promoting healthy body weight and improving a variety of related physiological factors, including serum serotonin levels, serum leptin levels, fat oxidation, cholesterol levels, and body mass index, in persons or other mammals, include administering to those persons or other mammals effective amounts of hydroxycitric acid or a combination of hydroxycitric acid, chromium and gymnemic acid, which work synergistically to further to promote healthy body weight and improve these physiological factors.

Description

The present invention relates generally to compositions and related methods for promoting healthy body weight, including reducing excess body weight or maintaining healthy body weight, and improving related health factors, such as cholesterol levels and body mass index, in persons and other mammals. Excess body weight is becoming more prevalent worldwide at an alarming rate, both in developing and developed countries. Approximately 61 percent of adults in the U.S. are overweight (i.e., having a body mass index (BMI) of greater than 25 kg / m2), while more than 26 percent of U.S. adults are obese (i.e., having a BMI of greater than 30 kg / m2). Obesity is the second leading cause of premature death in the U.S. Approximately 300,000 Americans die each year from complications caused by obesity. According to the World Health Organization, there are over 300 million obese adults worldwide. Environmental and behavioral changes brought about by economic development, modernization and urbaniz...

Examples

example

The effects of administering compositions within the scope of the methods of the present invention were tested. A double-blind, placebo-controlled human clinical trial was conducted using a composition incorporating: the HCA-SX extract described above (Super CitriMax™, supplied by InterHealth Nutraceuticals of Benicia, Calif.); and HCA-SX extract in combination with chromium (ChromeMate®, supplied by InterHealth), and Gymnema sylvestre extract (also supplied by InterHealth).

82 moderately obese human subjects completed the study. All subjects were placed on a daily diet of 2,000 kcal. All food was prepared and delivered to the subjects, and all food intake was strictly supervised by trained dieticians. All subjects also underwent a 30 minute walking exercise program, five times a week, which was supervised by a trained exercise specialist. The subjects were randomly divided into three groups. The subjects in the first group were given a placebo. The subjects in the second group wa...

The present invention relates generally to compositions and related methods for promoting healthy body weight, including reducing excess body weight or maintaining healthy body weight, and improving related health factors, such as cholesterol levels and body mass index, in persons and other mammals. Excess body weight is becoming more prevalent worldwide at an alarming rate, both in developing and developed countries. Approximately 61 percent of adults in the U.S. are overweight (i.e., having a body mass index (BMI) of greater than 25 kg / m2), while more than 26 percent of U.S. adults are obese (i.e., having a BMI of greater than 30 kg / m2). Obesity is the second leading cause of premature death in the U.S. Approximately 300,000 Americans die each year from complications caused by obesity. According to the World Health Organization, there are over 300 million obese adults worldwide. Environmental and behavioral changes brought about by economic development, modernization and urbaniz...

Examples

example

The effects of administering compositions within the scope of the methods of the present invention were tested. A double-blind, placebo-controlled human clinical trial was conducted using a composition incorporating: the HCA-SX extract described above (Super CitriMax™, supplied by InterHealth Nutraceuticals of Benicia, Calif.); and HCA-SX extract in combination with chromium (ChromeMate®, supplied by InterHealth), and Gymnema sylvestre extract (also supplied by InterHealth).

82 moderately obese human subjects completed the study. All subjects were placed on a daily diet of 2,000 kcal. All food was prepared and delivered to the subjects, and all food intake was strictly supervised by trained dieticians. All subjects also underwent a 30 minute walking exercise program, five times a week, which was supervised by a trained exercise specialist. The subjects were randomly divided into three groups. The subjects in the first group were given a placebo. The subjects in the second group wa...