51 results about "Gymnemic acid" patented technology

The present invention relates to a composition for promoting eye health in a companion animal. The composition comprising: at least one polyphenol selected from the group consisting of rosemary, rosemary extract, coffeic acid, coffee extract, turmeric extract, cucurmin, blueberry extract, grapeseed extract, rosemarinic acid, tea extract, and mixtures thereof.

The invention provides a method for extracting compound from kidney tea stalks and leaves, crushing the stalks and leaves, successively adopting water extraction, alcohol extraction, and ethyl acetate to extract water soluble, alcohol soluble and fat soluble compounds, which are rosemary acid, caffeic acid, bear fruit acid, Yuan er tea acid, isoflavone, rosemary acid acetate and other phenolic compounds and flavone compounds. The invention is a kidney tea compound extracting method, effective and applied to industrial production.

An extract of prunella spike for treating rheumatoid arthritis and improving immune suppression contains phenolic acid (60-70%) and rosemaric acid (14-21%). Its preparing process is also disclosed.

The invention relates to a method for extracting and separating rosemary essential oil, rosemary acid, ursolic acid and carnosic acid from rosemary leaves. The method mainly comprises the following steps that rosemary dry leaves are crushed and are then put into a water solution; temperature rise distillation is performed for 0.5h; distillates are collected to obtain the rosemary essential oil; after the distillation is completed, eight times of volume of 75-percent ethanol solution is added; extraction is performed for 2h at 60 DEG C; filtering is performed to obtain filtering liquid A; six times of volume of 75-percent ethanol solution is added into filtering slag; extraction is performed for 1h at 60 DEG C; filtering is performed to obtain filtering liquid B; the filtering liquid A andthe filtering liquid B are merged; concentration and centrifugation are performed to obtain a solid part and a water phase part; the water phase part is subjected to concentration spray treatment to obtain the rosemary acid; 60-percent ethanol solution is added into the solid part; after the dissolution, centrifugation is continuously performed and is repeated for three times to obtain the ursolicacid; the liquid part is subjected to concentration drying treatment to obtain the carnosic acid. The extracting method has the advantages that the process is simple; green and environment-friendly effects are achieved; the operation is convenient; the cost is low; the yield is high; the method is suitable for industrial production.

Botanical extracts and derivative compositions are described for activating or inhibiting the formation and development of bacterial biofilms. Gymnemic acids and other associated saponins are isolated from botanical extractions of the Gymnema sylvestre plant and are used to modulate bacterial biofilm virulence, especially biofilms associated with Staphylococcus aureus. Gurmarin, a polypeptide isolated from botanical extractions of the Gymnema sylvestre plant are used to inhibit biofilm formation, especially biofilms associated with Staphylococcus aureus. Methods for isolating gurmarin (as well as other peptides from botanical extracts) are described using isoelectric focusing separation techniques. Various uses for both research and health care concerns are described for the biofilm activators (modulators) and for the biofilm inhibitor.

The invention relates to a strawberry anti-staling agent. The strawberry anti-staling agent is characterized by comprising the main components: 0.1-0.5 g / L malic acid, 0.01-0.05 g / L rosemary acid, 0.1-0.5 g / L lentinan, 5-10 g / L chitosan, and the balance of water. The preparation method includes the steps that firstly, the malic acid and the rosemary acid are dissolved into water, then, the lentinan and the chitosan are added sequentially, the balance of water is supplemented, and strawberries are soaked or coated with the anti-staling agent for 1-3min. After the anti-staling agent is dried, the good anti-staling effect of the strawberries is achieved, the storage period and the shelf life are prolonged, and the strawberry anti-staling agent has good application prospects.

The invention discloses a chocolate and an industrialized production method thereof. The chocolate comprises the following raw materials in percent by weight: 5 percent-10 percent of flavor components, 5 percent-15 percent of cocoa butter, 10 percent-20 percent of milk powder, 50 percent-70 percent of cane sugar, 0.5 percent-1.0 percent of emulsifying agent and 0.01 percent -0.05 percent of sweetness inhibitor. The sweetness inhibitor is terpene ene indicant and / or gymnemic acid; and the dosage of the cocoa butter is replaced by the dosage of the properly-added sugar so as to properly reduce the dosage of the cocoa butter to reduce the production cost of the chocolate. About the problem that the sweetness of the chocolate is increased due to the dosage of the sugar, the invention reduces the sweetness of the chocolate by using the sweetness inhibitor and enables the product to have a healthcare function. In the invention, because of having the characteristics of low cost, low sweetness and low energy, the chocolate is the food which benefits the health.

Appetite control compositions comprise Gymnema sylvestre and an expectorant. In some embodiments, the appetite control compositions contain from about 3 mg to about 50 mg of gymnemic acid (an extract of Gymnema sylvestre), from about 10 mg to about 80 mg of glycyrrhizin (an extract of Glycyrrhiza glabra), high impact flavor, and a sweetening agent in a non-traditional dosage form. A non-traditional dosage form provides for the topical application of medicaments to the tissues of the mouth and tongue, more specifically, to the sweetness taste receptors of the tongue. By delivering gymnemic acid to the sweetness receptors of the tongue, the sensation of sweetness is blocked, thereby providing appetite control.

The invention provides a radix salivae miltiorrhizae hairy root SmHr1 with high-content phenolic compounds and a method for cultivating the same. The radix salivae miltiorrhizae hairy root contains salvianolic acid B, salvianolic acid K and a salvianolic acid and rosmarinci acid compounds; and the content of the radix salivae miltiorrhizae hairy root is higher than that of unileaf sage root. The cultivation method is applied and can remarkably improve the accumulated growth amount of the radix salivae miltiorrhizae hairy root and the content of the salvianolic acid compounds as medical compositions, thereby proving a high-yield strain for large-scale production of the compounds, reducing the production cost and promoting industrialized production.

The invention relates to a detergent containing a tulsi extract. The content of the tulsi extract is 0.01wt%-10wt%. The detergent contains high-concentration optimization active matter with anti-inflammatory and skin relieving functions, such as ursolic acid, rosmarinic acid and other triterpenoid compounds due to the contained tulsi extract, has better anti-inflammatory and relieving functions, has no irritation to skin and can be used as a detergent directly contacted with the skin.

The invention provides a sarcandra glabra extract with anti-influenza virus activity. Counted by the total weight of the sarcandra glabra extract, the sarcandra glabra extract comprises 0.020-0.040wt%of chlorogenic acid, 0.000-0.008wt% of isofraxidin, 0.025-0.060wt% of quercetin-3-O-beta-D-glucuronide and 0.083-0.158wt% of rosmarinic acid. The invention further provides a preparation method of the sarcandra glabra extract with the anti-influenza virus activity. The preparation method comprises the following steps: performing reflux extraction on sarcandra glabra for two times with deionized water, performing alcohol precipitation to obtain a dry sarcandra glabra water extract, then preparing the dry extract into a sample with a certain concentration, injecting the sample into macroporousadsorption resin, then eluting with an ethanol solution with the concentration of 20%, and collecting an eluate to obtain the sarcandra glabra extract with the anti-influenza virus activity. The sarcandra glabra extract and the preparation method have the advantages as follows: a help is provided for application of the sarcandra glabra extract to fighting against influenza; by the preparation method, the steps are simple and convenient, the operation is easy, quantification can be achieved, the repeatability is high; the preparation method is suitable for application of the extract to the large-scale industrial production process of a medicine in the later stage.

The invention belongs to the technical field of textile materials, and particularly relates to an efficient environment-friendly textile dye. The efficient environment-friendly textile dye mainly comprises acrylic emulsion, rosmarinic acid, sodium polymethacrylate, polyether siloxane, fatty alcohol-polyoxyethylene ether, ginseng-stem-leaf total saponin, Chinese hawthorn leaf extract and patchouli oil. The rosmarinic acid has the bacteriostatic effect, the anti-inflammatory effect, the antiviral effect, the anti-tumor effect, the anti-allergic effect, the antioxidant effect, the anti-thrombus and anti-platelet-aggregation effects, the radiation protection effect and the immunosuppressive effect, and has quite good stability. The polyether siloxane has the foam-eliminating and foam-suppressing effects, is free of toxic and side effects and is good in stability. Meanwhile, the ginseng-stem-leaf total saponin has high moisture absorption performance, and the Chinese hawthorn leaf extract has high moisture guiding performance. The patchouli oil has specific aromatic odor, the specific smell of the ginseng-stem-leaf total saponin and the specific smell of the Chinese hawthorn leaf extract can be covered, certain potential safety hazards of the health of the human body can be avoided, and the environment can be protected.

Disclosed is a toxic- and side effect-free externally-applied health-care cream for removing wrinkle, caring skin and keeping fitness, wherein the components include alpha-amyin palmitate, serine, vitamin E, praline, vinblastine, lycine, involucratolactone and vitamin B2. The body building and weight reducing components comprise haw lipase, vitamin B12, gamma-leukotriene, vitamin C, mesoinositol, gymnemic acid and m-nitro benzoic acid. The oil phase substance in other components include glycerin monostearate, stearic acid, propylene glycol, glycerin, dimethyl silicon oil, liquid paraffin wax and lanolin. The aqueous phase substance in other components include flavoring agents, non-ionic surface active agent and deionized soft water.

The invention discloses a novel tannase. An amino acid sequence of the tannase is shown as SEQ ID NO.3. The invention further discloses a cDNA of the novel tannase, and a nucleotide sequence of the cDNA is shown as SEQ ID NO.1. The invention further discloses an expression vector containing the novel tannase cDNA, recombinant tannase, a preparation method of the recombinant tannase and degradation application of the recombinant tannase by taking propyl gallate, tannic acid, epicatechin gallate, epigallocatechin-3-gallate, chlorogenic acid, rosmarinic acid and ethyl ferulate as substrates. The novel tannase and recombinant tannase have soluble expression in an escherichia coli expression system with high efficiency, and the recombinant tannase has efficient degradation effect on tannic acid, epicatechin gallate, epigallocatechin-3-gallate, chlorogenic acid, rosmarinic acid and ethyl ferulate.

The present invention is directed to a composition for sweetening an edible product, comprising at least a rebaudioside, characterized in that it further comprises gymnemic acid.

Methods for promoting healthy body weight and improving a variety of related physiological factors, including serum serotonin levels, serum leptin levels, fat oxidation, cholesterol levels, and body mass index, in persons or other mammals, include administering to those persons or other mammals effective amounts of hydroxycitric acid or a combination of hydroxycitric acid, chromium and gymnemic acid, which work synergistically to further to promote healthy body weight and improve these physiological factors.

The invention relates to a preparation method for three phenolic acid monomeric compounds in salvia prattii hemsl. The method comprises the steps of: (1) performing heat reflux extraction on the crushed roots of salvia prattii hemsl. with alcohol and combining the mixture to obtain an extraction liquid; (2) evaporating the extraction liquid at a reduced pressure to dryness to a constant weight to obtain salvia prattii hemsl.extract; (3) after dissolving the salvia prattii hemsl. extract with deionized water, extracting the extract by using petroleum ether, ethyl acetate and n-butanol sequentially to obtain four parts of extract; (4) dissolving the n-butanol extract in water and eluting the n-butanol extract by a D101 macroporous resin column to obtain an eluant containing phenolic acid substances; (6) evaporating the eluant to dryness to a constant weight to obtain coarse phenolic acid extract; and (7) separating the coarse phenolic acid extract in a n-hexane-ethyl acetate-methanol-water system by adopting high-speed counter-current chromatographic equipment to separately obtain monomeric compounds of three active phenolic acid substances: caffeic acid, rosmarinic acid and rosmarinic acid. The preparation method provided by the invention is simple and convenient, fast, effect and low in cost.

The invention belongs to the field of natural medicinal chemistry, and discloses a method for extracting gymnemic acid from gymnema sylvestre. The method comprises the steps that: a gymnema sylvestre raw material is crushed; 6-10 times of 30-90% ethanol is added for soak extraction 2-3 times; an extraction liquid is filtered and is subjected to ultrafiltration in an ultrafiltration membrane system; ethanol in a permeate is recovered, and the filtrate is subjected to absorption in anion exchange resin; the material is washed by using deionized water, until the material is colorless; the material is eluted by using 3-6BV 50-80% ethanol solution; active carbon is added fro reflux decolorization; an elution liquid is subjected to reduced-pressure standing crystallization; the material is filtered and dried, such that gymnemic acid is obtained. With the gymnemic acid production method provided by the invention, the process operation is simple, energy consumption is low, product purity is high, and the method is suitable for industrialized productions.

The invention relates to a medicinal composition for auxiliary treatment of diabetic coronary artery disease, which comprises the following components by weight (namely daily dosage): 1 to 50g of astragalus mongholicus, 1 to 50g of folium gymnemae, 1 to 20g of green tea extract, and 400 to 2,000IU of vitamin D, wherein the astragalus mongholicus and the folium gymnemae are subjected to alcohol heat extraction to obtain astragalus mongholicus and folium gymnemae extracts, and the contents of astragaloside and gymnemic acid can be detected; and the green tea extract and the vitamin D are mixed, and an excipient is added to prepare various oral preparations. The astragaloside can be used for reducing blood sugar; the green tea extract can be used for increasing HDL-C (high-density lipoproteincholesterol), reducing LDL-C (low-density lipoprotein cholesterol), and improving the blood situation of a patient; the astragaloside has the function of protecting heart and blood vessels; and the vitamin D has the effect of strengthening the curative effect of the Chinese medicament. Clinical applications prove that the medicinal composition can be used for assisting treatment of the patient with diabetic coronary artery disease, and remarkable effects can be obtained.

The invention discloses hair-blackening shampoo. By adding active ingredients of rosmarinic acid, a Chinese angelica extract product, a polyghace seche extract product and a curcuma tuber extract product into the shampoo, the shampoo is natural, safe and effective. The rosmarinic acid can promote expression of tyrosinase and induce generation of melanin; the Chinese angelica extract product can improve scalp microcirculation and promote scalp to absorb nutrients and also can provide the hair with rich trace elements; the polyghace seche extract product can activate tyrosinase activity and promote generation of melanin; and the curcuma tuber extract product has effects of invigorating blood circulation and promoting qi circulation and relieving depression. With synergism of the active ingredients, the shampoo can promote and activate blood circulation, promote transdermal absorption, improve scalp health, help effective active ingredients to rapidly reach the hair core, hair root and hair follicle, supplement effective ingredients essential to hair, activate tyrosinase activity, promote generation of melanin grains, blacken the hair and make the hair to be glossy.

The invention relates to use of danshinolic acid A composition in preparing ischemic penumbra treatment medicaments. The composition is composed of danshinolic acid A, alkannic acid, rosmarinic acid, danshinolic acid B and danshinolic acid C, wherein the composition is prepared in the following weight ratios: 90-99% of danshinolic acid A, 0.1-3% of alkannic acid, 0.1-3% of rosmarinic acid, 0.1-3% of danshinolic acid B and 0.1-5% of danshinolic acid C.

Methods for promoting healthy body weight and improving a variety of related physiological factors, including serum serotonin levels, serum leptin levels, fat oxidation, cholesterol levels, and body mass index, in persons or other mammals, include administering to those persons or other mammals effective amounts of hydroxycitric acid or a combination of hydroxycitric acid, chromium and gymnemic acid, which work synergistically to further to promote healthy body weight and improve these physiological factors.

The invention discloses a method for preparing rosemary acid and belongs to the technical field of plant extraction. The method includes: taking waste liquor produced by the process of producing rosemary lipid soluble antioxidants as raw material; preparing a rosemary acid feed solution, rosemary acid extraction phase, rosemary acid reextraction phase, rosemary acid film concentrate, rosemary acidpowder and purified extract by preparing N503 extract liquor to obtain rosemary acid powder containing more than 65-80% o f rosemary acid. The obtained rosemary acid powder is high in rosemary acid,good in separation effect and high in yield; the N503 extract liquor can be reused after purified, no pollution is caused to environment, and typical green production technology is achieved; standardequipment conforming to GMP (good manufacturing practice) specification is used, standard operation, moderate condition and low production cost are achieved, and the prepared rosemary acid powder is widely applicable to the fields of food, healthcare products, medicine and the like.

A disclosed gluconolactone-containing preservative comprises the following compositions in parts by weight: 40-70 parts of gluconolactone, 10-40 parts of one of sorbic acid and sorbates or a mixture thereof, and 10-30 parts of one of dehydroacetic acid and dehydroacetates or a mixture thereof. The gluconolactone-containing preservative is added with the natural safe raw materials rosmarinic acid and xanthyletin which have synergistic effect, and the gluconolactone-containing preservative is good in stability, can be stored at a shaded place for a long time, is not influenced by temperature and pH, and is substantially prolonged in shelf life and improved in food safety.

The invention relates to silibinin rosmarinate shown in a formula (I) specified in the description as well as pharmaceutical salts or solvates thereof. The invention further relates to a preparation method for a compound shown in the formula (I) as well as a medicine composition and medical application thereof. The compound shown in the formula (I) disclosed by the invention has a function of protecting liver cells, and can be used as a medicine for treating liver injuries and hepatic fibrosis diseases.

The invention relates to a medicinal composition for auxiliary treatment of diabetic coronary artery disease, which comprises the following components by weight (namely daily dosage): 1 to 50g of astragalus mongholicus, 1 to 50g of folium gymnemae, 1 to 20g of green tea extract, and 400 to 2,000IU of vitamin D, wherein the astragalus mongholicus and the folium gymnemae are subjected to alcohol heat extraction to obtain astragalus mongholicus and folium gymnemae extracts, and the contents of astragaloside and gymnemic acid can be detected; and the green tea extract and the vitamin D are mixed, and an excipient is added to prepare various oral preparations. The astragaloside can be used for reducing blood sugar; the green tea extract can be used for increasing HDL-C (high-density lipoproteincholesterol), reducing LDL-C (low-density lipoprotein cholesterol), and improving the blood situation of a patient; the astragaloside has the function of protecting heart and blood vessels; and the vitamin D has the effect of strengthening the curative effect of the Chinese medicament. Clinical applications prove that the medicinal composition can be used for assisting treatment of the patient with diabetic coronary artery disease, and remarkable effects can be obtained.

The present disclosure relates to compositions comprising gymnemic acid, together with a form of zinc to block the unpleasant bitter taste of gymnemic acid as well as to extend the sweet taste blocking properties of gymnemic acid, resulting in palatable compositions for delivery to the oral cavity to block sweet taste receptors located therein. The present disclosure also relates to methods of reducing sugar consumption and reducing calorie intake via administration of such compositions to a subject.