Compositions incorporating (-)-hydroxycitric acid, chromium, and gymnemic acid, and related methods for promoting healthy body weight and improving related health factors

Abstract

Methods for promoting healthy body weight and improving a variety of related physiological factors, including serum serotonin levels, serum leptin levels, fat oxidation, cholesterol levels, and body mass index, in persons or other mammals, include administering to those persons or other mammals effective amounts of hydroxycitric acid or a combination of hydroxycitric acid, chromium and gymnemic acid, which work synergistically to further to promote healthy body weight and improve these physiological factors.

Description

The present invention relates generally to compositions and related methods for promoting healthy body weight, including reducing excess body weight or maintaining healthy body weight, and improving related health factors, such as cholesterol levels and body mass index, in persons and other mammals. Excess body weight is becoming more prevalent worldwide at an alarming rate, both in developing and developed countries. Approximately 61 percent of adults in the U.S. are overweight (i.e., having a body mass index (BMI) of greater than 25 kg / m2), while more than 26 percent of U.S. adults are obese (i.e., having a BMI of greater than 30 kg / m2). Obesity is the second leading cause of premature death in the U.S. Approximately 300,000 Americans die each year from complications caused by obesity. According to the World Health Organization, there are over 300 million obese adults worldwide. Environmental and behavioral changes brought about by economic development, modernization and urbaniz...

AI Technical Summary

Benefits of technology

The present invention resides in a composition comprising hydroxycitric acid, chromium, and gymnemic acid. In preferred aspects of the invention, the hydroxycitric acid is bound to calcium and potassium. The hydroxycitric acid in the composition preferably is derived from a plant of the genus Garcinia, most preferably Garcinia Cambogia. The chromium in the composition preferably is niacin-bound chromium, and more preferably oxygen-coordinated niacin-bound chromium. The gymnemic acid in the composition preferably is derived from a plant of the genus Gymnema, most preferably Gymnema sylvestre. The composition may be in the form of a pill, tablet, capsule, lozenge, gum, liquid, powder, food, beverage or other orally administered form.

The present invention also resides in related methods for increasing serotonin level, decreasing leptin level, or increasing fat oxidation in a person or other mammal, incorporating identifying a person or other mammal that can benefit from increased serotonin level, decreased leptin level and/or increased fat oxidation, and administering to the person or other mammal a composition comprising hydroxycitric acid in an amount sufficient to provide the required effect. Preferred aspects of the method incorporate administration of hydroxycitric acid in forms as described above. The method preferably incorporates administering approximately 100 milligrams to approximately 5,000 milligrams of hydroxycitric acid daily, and more preferably approximately 2,700 milligrams to approximately 2,800 milligrams. In the method, the composition preferably is administered daily in three substantially equally divided doses, approximately 30 to 60 minutes before meals, preferably orally. In preferred aspects of the method, the composition also incorporates chromium and gymnemic acid in forms as described above. Preferably, the method incorporates admini...

Problems solved by technology

Increase in body weight results from an imbalance between energy intake and expenditure in a person, manifested by excessive expansion of adipose tissue mass in the person.

Obesity leads to a number of poor health factors.

In particular, obesity increases the risk of high blood pressure, hypertension, type II diabetes, arthritis, elevated cholesterol, and cancer.

Although 30-40% of obese people claim they are trying to lose or maintain body weight, their success rate is low.

Dietary approaches for the management of excess body weight have been unsuccessful due to improper caloric restriction and/or lack of physical exercise.

Low calorie diets can provide for temporary weight loss, but they have not proven themselves as long-term solutions for people trying to lose or maintain weight.

Unfortunately, these also frequently are accompanied by adverse side effects, some of which are life threatening.

These conditions are exacerbated by many factors, including poor diet, lack of exercise and obesity.

Overweight pets are at higher risk of developing health problems such as heart disease, skeletal problems, breathing problems, diabetes and arthritis.

These, however, have not been entirely effective treatments.

Diet modification and increased exercise can be difficult for some individuals to maintain for an extended period, and medications introduce the possibility of negative side effects.

Increased glycogen leve...